2018 2018 4 ............................................................................................................................................. 1 ...................................................................................................................................... 2 .............................................................................................................................................. 7 ............................................................................................................................................ 13 .................................................................................................................................... 27 2018 ( ) 1 2018 284,615,012.67 229,539,932.98 23.99% 42,789,001.00 75,549,674.60 -43.36% 39,006,399.78 49,252,805.86 -20.80% 73,389,657.57 70,119,683.98 4.66% / 0.11 0.19 -42.11% / 0.11 0.19 -42.11% 2.07% 3.85% -1.78% 2,787,233,759.01 2,773,013,798.83 0.51% 2,085,360,506.41 2,051,962,363.07 1.63% 401,000,000 -25,692.68 2,291,563.18 2 2018 1,762,083.23 421,227.44 666,579.95 3,782,601.22 -- 1 —— 1 4 2016 5 20 2016 515 2017 2 2017 7 19 36 EGFR 1 6 171 100 400 2018 CSCO 3 2018 EGFR BRAIN EGFR NSCLC EGFR 2 3 EGFR-TKI 2 1 2 3 “ ” 1 10 4 2018 20,241 0 10 19.97% 80,064,000 80,064,000 3,357,300 14.33% 57,456,000 57,456,000 32,292,260 9.61% 38,520,000 38,520,000 0 6.73% 27,000,000 27,000,000 18,900,000 WANG YINXIANG 5.84% 23,425,560 23,425,560 10,000,000 BETA PHARMA, INC. 5.55% 22,236,335 0 0 4.57% 18,309,029 0 0 LAV Equity (Hong Kong) Co., 2.69% 10,800,000 0 0 Limited ZHANG HANCHENG 2.32% 9,317,200 0 0 Sequoia Capital China GFII 2.26% 9,068,209 0 0 (HK) Limited 10 BETA PHARMA, INC. 22,236,335 22,236,335 18,309,029 18,309,029 LAV Equity (Hong Kong) Co., Limited 10,800,000 10,800,000 ZHANG HANCHENG 9,317,200 9,317,200 Sequoia Capital China GFII (HK) Limited 9,068,209 9,068,209 5,757,388 5,757,388 5,718,000 5,718,000 ( ) 2,780,098 2,780,098 2,296,439 2,296,439 1,723,960 1,723,960 5 2018 26.6993% 680,784 0.1698% WANG YINXIANG 5.84% WANG YINXIANG TAN FENLAI 1.08% TAN FENLAI WANG YINXIANG WANG YINXIANG 33.7891% 10 10 2 10 3 6 2018 5,636,172.21 3,638,455.38 54.91% 38,710,678.52 74,562,478.28 -48.08% 20,741,016.69 15,151,111.10 36.89% -24,564,496.38 -15,173,638.73 61.89% 12,684,022.39 9,440,352.37 34.36% 93,046,343.98 61,587,396.84 51.08% -3,810.52 5,070,038.81 -136,639.48 % 41,631,547.76 75,329,956.59 -44.73% 350,979,601.51 267,444,411.30 31.23% 3,904,186.51 27,201,625.95 -85.65% 139,482,514.68 97,005,811.87 43.79% 56,867,808.22 439,133,644.44 -87.05% 148,535,877.45 108,394,019.72 37.03% 57,156,368.00 149,994,000.00 -61.89% 50,000,000.00 - 2018 40.35% 28,461.50 23.99% 4,278.90 43.36% 3,900.64 20.80% 1 1,925.89 2 2,441.02 7 2018 3 1043.83 5 5 5 1 40.35% 2 2018 4 Ensartinib 2018 2-3 IND BPI-16350 3 8 2018 1 2014 10 25 Xcovery Holding Company LLC Xcovery Holdings, Inc. X-396 2017 3 27 Xcovery Holding Company LLC 300 Xcovery Holding Company LLC 2017 Xcovery D Xcovery 86.24% Xcovery Holding Company LLC 2 GUOJIAN XIE BETA BETA PHARMA SCIENTIFIC INC. DON ZHANG 2016 10 26 2017 SHANSHAN SHAO HONGLIANG CHU QIAN LIU SONG LU 2016 10 26 2017 GUOJIAN XIE 2017 08 08 2017-061 2017 2018-002 BPI-16350 2018 02 01 BPI-16350 Xcovery D-3 2018-008 2018 03 12 Equinox 65,735 0 882.98 9 2018 0 59,183.42 0.00% ( (3) (1) (2) (2)/(1) ) 2023 24,000 24,000 794.01 19,545.24 81.44% 12 31 2017 38,000 38,000 0 38,010.83 100.03% 09 30 13,618.25 32,189.63 2017 1,300 1,300 69.91 1,287.02 99.00% 07 31 2018 2,435 2,435 19.06 340.33 13.98% 12 31 -- 65,735 65,735 882.98 59,183.42 -- -- 13,618.25 32,189.63 -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- 65,735 65,735 882.98 59,183.42 -- -- 13,618.25 32,189.63 -- -- 10 2018 2016 11 2 46,003.50 2016 11 12 46,003.50 2016 11 22 2014 2015 11 2018 20% 2016 12 8 2016 2016-014 2016 12 21 2016-017 2017 257,727,409.55 322,266,228.64 10% 32,226,622.86 290,039,605.78 805,328,847.70 2016 72,180,000.00 1,023,188,453.48 2018 4 4 2017 401,000,000 10 1.5 60,150,000.00 12 2018 1 182,774,004.88 213,272,623.49 74,405,988.38 91,973,343.11 30,124,516.88 23,324,380.69 5,636,172.21 3,638,455.38 116,128,555.52 99,756,076.06 38,710,678.52 74,562,478.28 447,779,916.39 506,527,357.01 134,077,218.94 136,992,499.61 13 2018 15,269,416.56 15,269,416.56 449,233,604.22 454,770,238.29 460,766,771.89 408,379,933.28 547,299,785.92 545,670,165.84 306,205,762.51 277,813,121.15 413,584,000.09 413,584,000.09 1,919,602.18 2,094,111.46 6,343,933.31 7,159,208.54 4,753,747.00 4,753,747.00 2,339,453,842.62 2,266,486,441.82 2,787,233,759.01 2,773,013,798.83 250,000,000.00 200,000,000.00 10,000,000.00 10,000,000.00 93,444,621.64 121,788,288.43 396,438.00 75,304.80 35,278,939.93 57,335,849.62 20,741,016.69 15,151,111.10 216,672.76 422,430.55 14 2018 90,221,629.67 112,418,561.92 500,299,318.69 517,191,546.42 100,000,000.00 100,000,000.00 33,825,752.56 34,648,615.74 55,236,025.48 54,642,544.31 189,061,778.04 189,291,160.05 689,361,096.73 706,482,706.47 401,000,000.00 401,000,000.00 600,132,530.29 600,132,530.29 -24,564,496.38 -15,173,638.73 144,023,847.49 144,023,847.49 15 2018 964,768,625.01 921,979,624.02 2,085,360,506.41 2,051,962,363.07 12,512,155.87 14,568,729.29 2,097,872,662.28 2,066,531,092.36 2,787,233,759.01 2,773,013,798.83 2 156,884,135.92 154,033,483.24 74,405,988.38 91,973,343.11 8,560,038.95 1,513,038.95 527,248,473.73 480,760,730.33 116,128,555.52 99,756,076.06 20,000,000.00 55,000,000.00 903,227,192.50 883,036,671.69 59,588,895.68 59,588,895.68 1,023,605,106.56 1,023,605,106.56 433,311,134.72 438,255,509.24 16 2018 151,988,657.62 118,624,899.16 120,374,186.83 104,268,550.92 112,482,738.77 82,454,429.58 6,573,733.86 7,389,009.09 4,753,747.00 4,753,747.00 1,912,678,201.04 1,838,940,147.23 2,815,905,393.54 2,721,976,818.92 250,000,000.00 200,000,000.00 10,000,000.00 10,000,000.00 37,887,061.97 37,915,556.37 396,438.00 75,304.80 34,304,852.02 54,735,146.16 23,486,330.37 14,837,190.94 216,672.76 422,430.55 59,516,105.59 72,888,537.39 415,807,460.71 390,874,166.21 100,000,000.00 100,000,000.00 17 2018 33,825,752.56 34,648,615.74 1,835,731.71 1,242,250.54 135,661,484.27 135,890,866.28 551,468,944.98 526,765,032.49 401,000,000.00 401,000,000.00 626,999,485.46 626,999,485.46 144,023,847.49 144,023,847.49 1,092,413,115.61 1,023,188,453.48 2,264,436,448.56 2,195,211,786.43 2,815,905,393.54 2,721,976,818.92 3 284,615,012.67 229,539,932.98 284,615,012.67 229,539,932.98 235,537,155.06 168,882,396.90 12,684,022.39 9,440,352.37 18 2018 5,329,050.60 4,571,251.33 119,386,544.36 93,400,871.21 93,046,343.98 61,587,396.84 5,070,038.81 -136,639.48 21,154.92 19,164.63 “ ” “ ” 1,762,083.23 1,518,586.68 -2,381,077.89 “-” “-” -25,692.68 -102,757.05 791,463.18 “ ” 51,605,711.34 62,073,365.71 2,124,265.66 27,320,585.12 202,938.22 180,000.00 “ ” 53,527,038.78 89,213,950.83 11,895,491.02 13,883,994.24 “ ” 41,631,547.76 75,329,956.59 41,631,547.76 75,329,956.59 “ ” “ ” 42,789,001.00 75,549,674.60 -1,157,453.24 -219,718.01 -9,390,857.65 -926,349.25 -9,390,857.65 -926,349.25 19 2018 1. 2. -9,390,857.65 -926,349.25 1. 2. 3. 4. 5. -9,390,857.65 -926,349.25 6. 32,240,690.11 74,403,607.34 33,398,143.35 74,623,325.35 -1,157,453.24 -219,718.01 0.11 0.19 0.11 0.19 20 2018 4 284,615,012.67 229,370,121.66 12,684,022.39 9,440,352.37 5,315,973.16 4,571,251.33 119,386,544.36 93,400,871.21 67,422,898.58 60,094,050.58 3,108,132.42 -177,613.71 21,154.92 19,164.63 “ ” “ ” 1,762,083.23 3,810,403.47 -89,261.10 “-” -25,692.68 -102,757.05 791,463.18 “ ” 79,204,140.57 65,729,691.67 2,118,950.80 27,320,585.12 202,938.22 180,000.00 “ ” 81,120,153.15 92,870,276.79 11,895,491.02 13,883,994.24 “ ” 69,224,662.13 78,986,282.55 69,224,662.13 78,986,282.55 “ ” “ ” 1. 2. 21 2018 1. 2. 3. 4. 5. 6. 69,224,662.13 78,986,282.55 0.17 0.20 0.17 0.20 5 350,979,601.51 267,444,411.30 22 2018 3,909,501.37 27,201,625.95 354,889,102.88 294,646,037.25 17,325,371.63 15,093,270.13 83,958,260.46 75,582,563.55 40,733,298.54 36,844,707.72 139,482,514.68 97,005,811.87 281,499,445.31 224,526,353.27 73,389,657.57 70,119,683.98 56,867,808.22 439,133,644.44 8,718.00 120,300.00 56,876,526.22 439,253,944.44 148,535,877.45 108,394,019.72 57,156,368.00 149,994,000.00 23 2018 205,692,245.45 258,388,019.72 -148,815,719.23 180,865,924.72 50,000,000.00 50,000,000.00 3,758,361.12 10,383,446.50 3,758,361.12 10,383,446.50 46,241,638.88 -10,383,446.50 -1,314,195.83 -41,560.28 -30,498,618.61 240,560,601.92 213,272,623.49 153,921,641.42 182,774,004.88 394,482,243.34 6 350,979,601.51 267,264,411.30 1,929,999.77 27,094,861.24 24 2018 352,909,601.28 294,359,272.54 34,997,250.70 15,093,270.13 80,155,988.98 74,310,922.78 40,382,343.38 36,580,423.62 107,025,552.16 96,375,768.20 262,561,135.22 222,360,384.73 90,348,466.06 71,998,887.81 56,867,808.22 439,133,644.44 8,718.00 120,300.00 56,876,526.22 439,253,944.44 88,779,602.88 70,623,522.32 57,156,368.00 161,073,160.00 145,935,970.88 231,696,682.32 -89,059,444.66 207,557,262.12 50,000,000.00 50,000,000.00 100,000,000.00 25 2018 3,758,361.12 94,680,000.00 38,210,000.00 98,438,361.12 38,210,000.00 1,561,638.88 -38,210,000.00 -7.60 -1.18 2,850,652.68 241,346,148.75 154,033,483.24 135,110,121.16 156,884,135.92 376,456,269.91 26 贝达药业股份有限公司董事、高级管理人员 关于《2018 年第一季度报告》的书面确认意见 根据《证券法》第六十八条的规定,以及《创业板信息披露业务备忘录第 10 号:定期报告披露相关事项(2018 年 2 月修订)》等法律法规和交易所规则的相关 要求,作为贝达药业股份有限公司的董事、高级管理人员,我们在全面审核公司 《2018 年第一季度报告》后认为: 公司严格按照公司财务制度规范运作,公司《2018 年第一季度报告》包含的 信息公允、全面、真实地反映了公司本报告期的财务状况和经营成果等事项。 我们保证公司《2018 年第一季度报告》所披露的信息真实、准确、完整,承 诺本报告所载资料不存在任何虚假记载、误导性陈述或者重大遗漏,并对其内容 的真实性、准确性和完整性承担个别及连带责任。 (以下无正文)