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公司公告

健康元:健康元药业集团股份有限公司2021年年度报告(英文版)2022-03-31  

                              Important
      Notice

 I     The Board of Directors (the“Board”), the Board of Supervisors and directors, supervisors and senior management of the
       Company hereby warrant the truthfulness, accuracy and completeness of the contents of this annual report (the“Report”), and
       that there are no false representations, misleading statements or material omissions contained in the Report, and severally and
       jointly accept responsibility.

 II    All directors of the company have attended the Board meeting.

III    Grant Thornton (Special General Partnership) Issued a standard unqualied audit report for the Company.

IV     Mr. Zhu Baoguo ( 朱 保 国 ), the person-in-charge of the Company, and Mr. Qiu Qingfeng ( 邱 庆 丰 ), the person-in-charge of
       accounting work and the person-in-charge of the accounting department (the head of the accounting department) declare that
       they hereby warrant the truthfulness, accuracy and completeness of the nancial statements contained in the Report.

 V     Profit distribution plan or plan for conversion of capital reserve to share capital approved by the Board resolution during the
       Reporting Period
       Based on the audit conducted by Grant Thornton (Special General Partnership), the Parent Company generated net profit of
       RMB 1,248,797,138.93, 10% of which was contributed to the statutory surplus reserve, namely RMB 124,879,713.89, the
       remainder of which, together with undistributed profits from last year RMB 564,932,141.19, subtracting cash dividends from
       last year RMB 288,675,388.05, is the current year Profits available for distribution to shareholders RMB 1,400,174,178.18.
       The Company plans to distribute cash dividends for the fiscal year 2021, based on the total number of shares for dividend
       distribution, which is dened by the total shares of Company, minus the shares in the Share Repurchase Account, on the equity
       registration date designated by the annual prot distribution plan. The Company plans to distribute cash dividend of RMB 1.50
       (tax inclusive) for every 10 shares of to all shareholders of the Company, and the remaining undistributed profits to be carried
       forward to the following year.

VI     Risk declaration for the forward-looking statements
       √ Applicable □ N/A
       The Report contains forward-looking statements which involve the future plans, development strategies, etc. of the Company,
       yet do not constitute substantive undertakings of the Company to investors. Investors should exercise caution prior to making
       investment decisions.

VII Whether there is non-operating use of funds by the controlling shareholder and their related parties
    No

VIII Whether there is a violation of the prescribed decision-making procedures to provide external guarantees
     No

IX     Whether more than half of directors cannot warrant the truthfulness, accuracy and completeness of the Report disclosed by the
       Company
       No

 X      Signicant risk warnings
        There is no exceptionally significant risk that will have a material impact on the production and operation of the Company
        during the Reporting Period. In this report, the Company has elaborated on the risks and countermeasures that the Company may
        face in the course of production and operation, including industry policy risks, market risks, environmental risks, risk in price
        and supply of raw materials, R&D risks, risk of the normalization of Covid-19 pandemic. For more information, please refer to
      “Possible risks”part in Chapter III Management Discussion and Analysis.

XI     Others
       □ Applicable √ N/A

XII The Report is prepared in both Chinese and English. In case of any ambiguity in the understanding of the Chinese and English
    texts, the Chinese version shall prevail.

                                                                                                                                       1
     Table of
     Contents

Chairman's Statement .........................................................................................................................................................3
Financial Highlights ............................................................................................................................................................6
Chapter 1 Denitions ..........................................................................................................................................................8
Chapter 2 Company Prole and Major Financial Indicators ............................................................................................10
Chapter 3 Management Discussion and Analysis .............................................................................................................15
Chapter 4 Corporate Governance ......................................................................................................................................60
Chapter 5 Environmental and Social Responsibility ........................................................................................................85
Chapter 6 Major Events .................................................................................................................................................. 110
Chapter 7 Changes in Equity and Shareholders ..............................................................................................................124
Chapter 8 Information on Preferred Shares ....................................................................................................................130
Chapter 9 Information on Bonds .....................................................................................................................................131
Chapter 10 Financial Statements ....................................................................................................................................132



                         The Financial Statements signed and sealed by the person-in-charge of the Company, the person-in-charge of the
                         Company's accounting work and the person-in-charge of the accounting department (the head of the accounting
                         department)
 List of lings           The original document of the auditors’report sealed by the accounting firm and signed and sealed by the
                         certied public accountants.
                         The original copies of all documents and announcements of the Company which have been disclosed to the
                         public on the website designated by CSRC during the Reporting Period




2
    Chairman's
    Statement

Dear shareholders,

The year 2021, marking the opening year of the 14th Five-Year Plan, was a critical year for China to deepen the reforms of the
pharmaceutical and health systems. Starting there, the reform of the“three-med”linkage covering medicine, medical care, and
medical insurance headed towards a deeper level. For the healthcare industry, the past year was full of unprecedented opportunities
and challenges. The year 2021 was a year when COVID-19 pandemic continued to spread around the world. The pandemic changed
the habits and order of human society, regardless of national boundaries. We are experiencing a pandemic, a turnaround and a change
unseen in a hundred years.

Faced with the industry-wide“big test”, Joincare adheres to, as it always does, the mission of“For the health, For the future”and
the vision of“Attentively developing high-quality medicines and innovative medicines”. Centered on medicine development, we
were firmly implementing the dual-drive strategy of developing platforms of both innovative medicines and high-barrier complex
preparations. Oriented by the three-in-one goal of innovative transformation, integrated operation, and sustainable growth, we
gave full play to the advantages of production-research integration and “APIs-preparations integration” across the
entire industry. We sought “opportunities” from “crisis” and pursued growth while ensuring stability. We united as one,
worked hard, and finally successfully achieved our annual business goals and targets, achieving double-digit growth in both
revenues and profits given that we have been continuously increasing investments in R&D.

In 2021, Joincare realized total revenues of RMB 15,904 million, representing a year-on-year increase of approximately 17.62%;
realized a net profit attributable to shareholders of listed companies of RMB 1,328 million, representing a year-on-year increase of
approximately 18.57%; and realized a net prot attributable to shareholders of listed companies after deduction of the extraordinary
gains and losses of RMB 1,225 million, representing a year-on-year increase of approximately 26.72%.

Robust financial performance builds a solid foundation for us to generate higher returns for our shareholders.

We attach great importance to our shareholder returns. In addition to completing the first share repurchase mandate with a total
amount of RMB700 million in the secondary market in September 2021, we launched a new share buyback plan in the secondary
market with a mandate of total amount of RMB 300 million to RMB600 million at the end of the reporing period; those share
buyback mandtes illustrate the sincere confidence of the Borad and the management level in the intrinsic vaule of Joincare. Based
on our operating results and overall financial position in 2021, the Board of Directors propose that we continue to adopt a stable
prot distribution scheme. Specically, a cash dividend of RMB 1.50 (tax inclusive) will be distributed to all shareholders for every
10 shares, based on the total number of shares for dividend distribution, which is dened by the total shares of Company, minus the
shares in the Share Repurchase Account, on the equity registration date designated by the annual profit distribution plan.The profit
distribution scheme for 2021 is yet to be reviewed and approved at the Company's 2021 Annual General Meeting.

In 2021, our main business structure and product matrix have been continuously optimizing, making the Group's
advantages of endogenous growth much more significant.

We achieved an obvious sales growth in the segment of chemical drug preparations, and an especially rapid year-on-year sales
growth in key advantageous fields, such as respiratory, gastroenterology and gonadotropic hormones. In the segment of APIs,
our high-end characteristic APIs steadily gained more market shares and profits. We have been continuing doing great jobs in
pipeline commercialization and recording increased sales volumes in our inhalation preparations segment, reconfirming the
growth momentum and our status as a leader of the inhalation medicine market niche in China.The Sale Volumes of The Ilaprazole
series, one of our innovative medicines, and of Leuprorelin Acetate Microspheres for Injection, one of our high-barrier complex
preparations continue to grow rapidly, providing a strong engine for the rapid development for Joincare.

In terms of product innovation, In the innovation development in line with the trend of the times, we gradually worked out
a set of mature system, and continuously polished and optimized along each dimension, not letting go of any opportunity
for leapfrog development under the tone of progressive innovation.

We continued to signicantly increase our R&D investment for several years, from RMB 609 million in 2016 to RMB1,850 million


                                                                                                                                   3
 in 2021, more than tripling in ve years.“Taking the needs of patients as our responsibility and being ambitious to be the pioneer”,
 we have developed innovative R&D technology platforms for high-barrier complex preparations, including inhalation administration,
 antibody, and sustained-release microspheres. In 2021, the R&D of many innovative medicine products in the Group's pipeline made
 signicant progress.

 We are expanding our business territory at a steady pace. In 2021, Recombinant SARS-CoV-2 Fusion Protein Vaccine (V-01), jointly
 developed by the Institute of Biophysics of the Chinese Academy of Sciences and Joincare, achieved milestones in terms of both
 R&D and commercialization. Currently, we are actively promoting the launch of V-01 to the market, hoping to contribute to the
 world-wide fight against the COVID-19 epidemic at the earliest possible time. As Joincare's first product to conduct the phase III
 global multi-center clinical trials, the smooth progress of V-01's phase III clinical trials have also accumulated richer resources and
 experience in organizational management, partnerships, team capabilities and registration applications for the internationalization of
 our innovative medicines.

 In 2021, Joincare Biopharmaceutical Research Institute was established. We successively built 6 R&D platforms of industrial strain
 improvement, synthetic biology, biocatalysis, fermentation scale-up, product extraction, and biochemical APIs. In addition, we
 signed a strategic cooperation agreement with Tencent Quantum Lab to joint our eorts in establishing a system enabled by quantum
 computing and AI for research on microbial synthetic biology and R&D of relevant drugs. We will apply AI technology to better
 serve the Group's R&D and innovation, and boost the development and upgrading of China's medical and healthcare industry.

 In 2021, in terms of business model innovation, we strive to embrace a digital marketing mode.

 Our“Healthy Lung”Challenge for the World COPD Day launched on TikTok was a precedent for digital marketing in the industry. In
 China, the rate of awareness and rate of standardized diagnosis and treatment of Chronic obstructive pulmonary disease (COPD) and
 similar chronic respiratory diseases are low, but the patient population is quite large. Joincare has bravely stepped out of the“comfort
 zone”, create a“friend zone”and build an“ecosphere”. With the clear principle of“patient-centered”, We strive to empower
 all links including education, screening, diagnosis, treatment, and medication monitoring, form a closed-loop consisting of doctors,
 hospitals, patients and drug companies, and explore the external huge market of chronic disease management with private trac, so as to
 realize real-time interaction between consumers and brands, and inject new vitality to commercialization of the Company.

 Only when we share the same frequency can we resonate. While focusing on our own development, the Group always
 persists in contributing to the social welfare business and actively undertakes social responsibilities We pay great attention
 to our sustainable development, and actively focus on the internal regulatory environment and external policy guidance.
 Considering China's 14th Five-Year Plan and the local government's development plan, the Group has formulated a CSR
 strategy and goals adapting to its current business situation. We adhere to social welfare undertakings and strive to make
 achievement in both enterprise profits and social benefits.

The inhalation medicine products are the best and most effective therapy methods for respiratory diseases, such as asthma and
  COPD, and the R&D investments in this market niche are highly recommended by the Chinese government. However, due to
the high barriers to the R&D and production of inhalation medicine products, the market shares have been dominated by foreign
  manufacturers for a long time. In March 2021, the National Drug Reimbursement List (2020) was ocially implemented. Joincare's
  blockbuster product, Levosalbutamol Hydrochloride Nebuliser Solution, as the only made-in-China inhalation preparation
  included in the List for negotiation led by National Health Security Administration, started to benet more patients with respiratory
  diseases. In June 2021, Joincare's three inhalation preparation products, including“Budesonide Suspension for Inhalation” 雾 舒 ),
“Compound Ipratropium Bromide Solution for Inhalation” 舒坦琳 ), and“Ipratropium Bromide Solution for Inhalation” 丽雾安 ),
  were listed in the fifth round of the national centralized drug procurement program. This enabled more Chinese people to get high-
  quality inhalation preparations at a more aordable price.

 In 2021, our footprint for public welfare for chronic diseases prevention and treatment further expanded. Since the end of 2018 until
 today, the“Access to Public Welfare for Chronic Diseases Prevention and Treatment Program”, established jointly by the us and
 the Livzon Group, has been implemented in various regions, including Sichuan Province, Shanxi Province, Gansu Province, Jilin
 Province, Tibet, Henan Province, Anhui Province, Hunan Province and Jiangxi Province, and delivered pharmaceuticals needed
 urgently by middle and elder age patients with chronic diseases.

 In 2021, Henan was hit by a flood and drew nation-wide concerns. To help the flood-stricken areas, Joincare and Livzon Group


 4
                                                                                                                Annual Report
                                                                                                                        2021


quickly joined hands to donate a total of RMB 10 million in cash and RMB 10 million in medicines to boost related medical
assistance and post-disaster reconstruction.

The year 2022 will be the 30th anniversary of Joincare. Looking back, we have seized opportunities given by the times again and
again, especially in the context of the“Healthy China”development strategy officially proposed in the report of the 19th National
Congress of the Communist Party of China. We have been chorusing with the times and produced triumphs in terms of innovation,
transformation and development. There are full of uncertainties in the current global macro and economic environments.

For Joincare, an enterprise with revenues of tens of billions and a history of three decades, achieving continuous innovation and
growth call for arduous efforts. Looking into 2022, we will continue to take the courage of“starting from the scratch”and work
hard together to accelerate the progress of R&D, innovation, and commercialization of new products. We will also thoroughly plan
the next-generation product matrix to further strengthen the Company's competitiveness. We are full of confidence in fulfilling our
business goals for 2022 and realizing our future strategic vision.

On behalf of the Board of the Company, I would like to take this opportunity to express my sincere thanks to all Shareholders, all
sta of the Group and business partners for their long-lasting care, companion and support.




                                                                                                      Chairman: Zhu Baoguo
                                                                                                         29 March 2022




                                                                                                                                 5
    Financial
    Highlights




6
7
      Chapter 1
      Definitions


    I Definitions

      In this Report, unless the context otherwise requires, the following expressions shall have the following meanings:


       Denitions of common terms
       CSRC                             Refers to China Securities Regulatory Commission
       Baiyeyuan or the Controlling
                                        Refers to Shenzhen Baiyeyuan Investment Co., Ltd. * ( 深圳市百业源投资有限公司 )
       Shareholder
                                                    Joincare Pharmaceutical Group Industry Co., Ltd. *
       Company or the Company           Refers to
                                                    ( 健康元药业集团股份有限公司 )
       GMP                              Refers to Good Manufacturing Practice
       GSP                              Refers to Good Supply Practice
       BE                               Refers to Bioequivalence
       BLA                              Refers to Biologics License Application
       IND                              Refers to Investigational New Drug Application
       WHO                              Refers to World Health Organazation
       Livzon Group                     Refers to Livzon Pharmaceutical Group Inc.* ( 丽珠医药集团股份有限公司 )
       Haibin Pharma                    Refers to Shenzhen Haibin Pharmaceutical Co., Ltd.* ( 深圳市海滨制药有限公司 )
       Joincare Haibin                  Refers to Joincare Haibin Pharmaceutical Co., Ltd.* ( 健康元海滨药业有限公司 )
       Xinxiang Haibin                  Refers to Xinxiang Haibin Pharmaceutical Co., Ltd. * ( 新乡海滨药业有限公司 )
       Taitai Pharmaceutical            Refers to Shenzhen Taitai Pharmaceutical Co., Ltd. * ( 深圳太太药业有限公司 )
       Taitai Genomics                  Refers to Shenzhen Taitai Genomics Inc.Co.,Ltd. * ( 深圳太太基因工程有限公司 )
       Joincare Biopharmaceutical                   Henan Province Joincare Biopharmaceutical Research Institute Co., Ltd. *
                                        Refers to
       Research Institute                           ( 河南省健康元生物医药研究院有限公司 )
                                                    Jiaozuo Joincare Bio Technological Co., Ltd.*
       Jiaozuo Joincare                 Refers to
                                                    ( 焦作健康元生物制品有限公司 )
       Joincare Daily-Use               Refers to Joincare Daily-Use & Health Care Co., Ltd. * ( 健康元日用保健品有限公司 )
       Topsino                          Refers to Topsino Industries Limited * ( 天诚实业有限公司 )
                                                    Shenzhen Fenglei Electric Power Investment Co., Ltd. *
       Fenglei Electric Power           Refers to
                                                    ( 深圳市风雷电力投资有限公司 )
                                                    Zhuhai Jiankangyuan Biology Medicine Co.,Ltd. *
       Zhuhai Jiankangyuan              Refers to
                                                    ( 珠海健康元生物医药有限公司 )
       Health Pharmaceutical            Refers to Health Pharmaceutical (China) Co., Ltd. * ( 健康药业(中国)有限公司 )
       Hiyeah Industry                  Refers to Shenzhen Hiyeah Industry Co., Ltd. * ( 深圳市喜悦实业有限公司 )
                                                    Shanghai Frontier Health Pharmaceutical Technology Co., Ltd. *
       Shanghai Frontier                Refers to
                                                    ( 上海方予健康医药科技有限公司 )
       Joincare Special Medicine                    Joincare (Guangdong) Special Medicine Food Co., Ltd. *
                                        Refers to
       Food                                         ( 健康元(广东)特医食品有限公司 )
       Joincare BVI                     Refers to Joincare Pharmaceutical Group Industry Co., Ltd
       Livzon MAB                       Refers to Livzon MABPharm Inc. * ( 珠海市丽珠单抗生物技术有限公司 )
       Livzon Diagnostics               Refers to Zhuhai Livzon Diagnostics Inc. * ( 珠海丽珠试剂股份有限公司 )
                                                    Livzon Group Fuzhou Fuxing Pharmaceutical Co., Ltd.*
       Fuzhou Fuxing                    Refers to
                                                    ( 丽珠集团福州福兴医药有限公司 )
                                                    Livzon Group Xinbeijiang Pharmaceutical Manufacturing Inc.*
       Xinbeijiang Pharmaceutical       Refers to
                                                    ( 丽珠集团新北江制药股份有限公司 )




8
                                                                                                       Annual Report
                                                                                                               2021


Denitions of common terms
                                          Livzon Group (Ningxia) Pharmaceutical Manufacturing Co., Ltd.*
Ningxia Pharmaceutical        Refers to
                                          ( 丽珠集团(宁夏)制药有限公司 )
Gutian Fuxing                 Refers to Gutian Fuxing Pharmaceutical Co., Ltd. * ( 古田福兴医药有限公司 )
                                          Zhuhai FTZ Livzon Hecheng Pharmaceutical Manufacturing Co., Ltd. *
Livzon Hecheng                Refers to
                                          ( 珠海保税区丽珠合成制药有限公司 )
                                          Livzon Group Limin Pharmaceutical Manufacturing Factory *
Livzon Limin                  Refers to
                                          ( 丽珠集团利民制药厂 )
Livzon Pharmaceutical Factory Refers to Livzon Group Livzon Pharmaceutical Factory * ( 丽珠集团丽珠制药厂 )
                                          Jiaozuo Livzon Hecheng Pharmaceutical Manufacturing Co., Ltd.*
Jiaozuo Hecheng               Refers to
                                          ( 焦作丽珠合成制药有限公司 )
                                          Shanghai Livzon Pharmaceutical Manufacturing Co., Ltd. *
Shanghai Livzon               Refers to
                                          ( 上海丽珠制药有限公司 )
                                          Sichuan Guangda Pharmaceutical Manufacturing Co., Ltd. *
Sichuan Guangda               Refers to
                                          ( 四川光大制药有限公司 )
                                          Jiaozuo Jinguan Jiahua Electric Power Co., Ltd. *
Jinguan Electric Power        Refers to
                                          ( 焦作金冠嘉华电力有限公司 )
                                          Tianjin Tasly Healthcare Industry Investment Partnership (Limited Partnership)*
Tianjin Tasly                 Refers to
                                          ( 天津天士力健康产业投资合伙企业(有限合伙))
Tianjin Tongrentang           Refers to Tianjin Tongrentang Group Co., Ltd. * ( 天津同仁堂集团股份有限公司 )
Sanmed Biotech                Refers to Zhuhai Sanmed Biotech Inc. * ( 珠海圣美生物诊断技术有限公司 )
Livzon Biologics or Livzon
                              Refers to Livzon Biologics Limited
Cayman
Livzon International          Refers to Livzon International Limited
YF                            Refers to YF Pharmab Limited
Kadi Biotechnology            Refers to Zhuhai Kadi Medical Biotechnology Inc. * ( 珠海市卡迪生物医药有限公司 )
                                          Hainan Lisheng Juyuan Investment Partnership (Limited Partnership) *
Lisheng Juyuan                Refers to
                                          ( 海南丽生聚源投资合伙企业(有限合伙))
Livzon HK                     Refers to Livzon Biologics Hong Kong Limited * ( 丽珠生物科技香港有限公司 )
                                          Zhuhai Livzon Biotechnology Co., Ltd.*
LivzonBio                     Refers to
                                          ( 珠海市丽珠生物医药科技有限公司 )
COVID-19                      Refers to A new coronavirus (SARS-CoV-2)
COVID-19 pandemic or
                              Refers to The outbreak of the disease caused by a new coronavirus called SARS-CoV-2
pandemic
Ruihua Certied Public
                              Refers to Ruihua Certied Public Accountants (Special General Partnership)
Accountants
Grant Thornton                Refers to Grant Thornton (Special General Partnership)
Reporting Period              Refers to From 1 January 2021 to 31 December 2021
End of the Reporting Period   Refers to 31 December 2021
Currency or unit              Refers to RMB unless otherwise specied




                                                                                                                        9
     Chapter 2
     Company Profile and Major Financial Indicators


 I Company profile

     Chinese name of the Company                                   健康元药业集团股份有限公司
     Abbreviation of the Chinese name                              健康元
     English name                                                  Joincare Pharmaceutical Group Industry Co., Ltd.
     Abbreviation of the English name                              Joincare
     Legal representative of the Company                           Zhu Baoguo


 II Contact persons and contact information

                      Board Secretary                                         Representatives of Securities Aairs
     Name             Zhao Fengguang ( 赵凤光 )                               Li Hongtao( 李洪涛 ) Luo Xiao( 罗逍 )
                      Joincare Pharmaceutical Group Building, No. 17,         Joincare Pharmaceutical Group Building, No. 17,
     Address          Langshan Road, North District, Hi-tech Zone,            Langshan Road, North District, Hi-tech Zone,
                      Nanshan District, Shenzhen                              Nanshan District, Shenzhen
     Telephone        0755-86252656, 0755-86252388                            0755-86252656, 0755-86252388
     Fax              0755-86252165                                           0755-86252165
     E-mail           zhaofengguang@joincare.com                              lihongtao@joincare.com luoxiao@joincare.com


III Introduction of the Company's basic information

                                   Joincare Pharmaceutical Group Building, No. 17, Langshan Road, North District, Hi-tech
     Registered address
                                   Zone, Nanshan District, Shenzhen
                                   Registered at B5, Hengfeng Industrial City, Hezhou Community, Huangtian Village, Xin’an
                                   Town, Bao’an County on 18 December 1992
                                   Changed its registered address to 4-5/F, Dongpeng Building, Shangmeilin Industrial Area,
                                   Futian District, Shenzhen on 25 May 1994
                                   Changed its registered address to 24/F, Block B, Fujian Building, Caitian South Road, Futian
                                   District, Shenzhen on 4 July 1995
                                   Changed its registered address to 23/F, Diwang Building, Shun Hing Square, No. 333,
     Historical changes in         Shennan East Road, Shenzhen on 20 June 1997
     registered address            Changed its registered address to Taitai Pharmaceutical Industrial Building, the 5th Industrial
                                   Area, Nanshan District, Shenzhen on 22 September 2000
                                   Changed its registered address to 23/F, Diwang Building, Shun Hing Square, No. 5002,
                                   Shennan East Road, Luohu District, Shenzhen on 4 June 2003
                                   Changed its registered address to Joincare Pharmaceutical Group Building, No. 17, Langshan
                                   Road, North District, Hi-tech Zone, Nanshan District, Shenzhen on 29 January 2008
                                   Changed its registered address to Joincare Pharmaceutical Group Building, No. 17, Langshan
                                   Road, North District, Hi-tech Zone, Nanshan District, Shenzhen on 27 November 2012
                                   Joincare Pharmaceutical Group Building, No. 17, Langshan Road, North District, Hi-tech
     Oce address
                                   Zone, Nanshan District, Shenzhen
     Postal code of Oce address    518057
     Website                       www.joincare.com
     E-mail                        joincare@joincare.com




10
                                                                                                                   Annual Report
                                                                                                                           2021


IV Information disclosure and place of reports prepared for inquiry

                                                                       China Securities Journal, Securities Times, Securities Daily,
    Designated media and website for disclosing annual report
                                                                       and Shanghai Securities News
    Stock exchange website for disclosing annual report                www.sse.com.cn
    The place for inspection of annual report                          Oce address of the Company


V Company Stock Profile

                                                         Company Stock Prole
    Class of stock             Listed on               Stock Abbreviation       Stock code       Stock abbreviation prior to change
    A Share            Shanghai Stock Exchange              健康元               600380                太太药业、S 健康元


VI Other relevant information

                                                Name                         Grant Thornton (Special General Partnership)
                                                                             5th Floor, Scitech Palace, 22 Jianguomen Wai Avenue,
    Accounting rm appointed by the              Oce address
                                                                             Chaoyang District, Beijing
    Company (domestic)
                                                Name of the signing
                                                                             Wang Ying ( 王莹 ) and Wang Qilai ( 王其来 )
                                                accountants
                                                Name                         Minsheng Securities Co., Ltd.
                                                                             17th Floor, Block D, Minsheng Financial Centre, 28
                                                Oce address
    Sponsor appointed for performing                                         Jianguomen Nei Avenue, Dongcheng District, Beijing
    the duty of continuous supervisory          Name of sponsor
    responsibilities during the Reporting       representatives signing      Yu Chunyu( 于春宇 ) and Ma Chujin ( 马初进 )
    Period                                      the report
                                                Period of continuous
                                                                             From 24 October 2018 to 31 December 2019
                                                supervision


   Note: According to Article 29 of Measures for the Administration of the Sponsorship Business for the Offering and Listing
   of Securities, for offering of new stocks or convertible corporate bonds by a company listed on the main board, the period
   of continuous supervision and guidance shall be the remaining time of the current year of the listing of securities and the
   following one full accounting year. As the Company issued shares to the public by allotment on 24 October 2018, the period
   of continuous supervision should start from the completion of this issuance and end on 31 December 2019. Furthermore,
   according to Article 13 of the Guidelines of Shanghai Stock Exchange for Self-Regulation Rules for Listed Companies No.
   11 - Continuous Supervision, the sponsor shall continue to perform the obligations of continuous supervision if the funds
   raised have not been fully utilized upon the expiration of the continuous supervision period. During the Reporting Period,
   funds raised in this issuance have not yet been fully utilized, so the sponsor, Minsheng Securities, shall continue to perform its
   continuous supervision obligations in respect of the deposit and utilization of the funds raised.




                                                                                                                                       11
VII Major accounting data and financial indicators in the last three years

 1) Major accounting data
                                                                                                         Unit:Yuan Currency: RMB
     Major accounting data                                    2021                2020     YoY Change (%)                    2019
     Revenues                                     15,903,688,266.59 13,521,605,768.20                 17.62 11,980,153,109.49
     Net prot attributable to shareholders of
                                                   1,328,499,432.05   1,120,439,799.25                18.57      894,346,741.25
     the listed company
     Net prot attributable to shareholders
     of the listed company after deduction of      1,224,997,371.57    966,680,220.14                 26.72      828,859,988.18
     extraordinary gains and losses
     Net cash ow from operating activities         2,563,089,045.24   3,024,999,592.24                -15.27   2,312,447,687.11
                                                                                      Increase or decrease
                                                                                        at the end over the
                                                       End of 2021        End of 2020                                  End of 2019
                                                                                       same period of last
                                                                                                  year (%)
     Net assets attributable to shareholders of
                                                  11,820,293,656.69 11,096,125,890.51                   6.53 10,355,964,661.31
     the listed company
     Total assets                                 31,103,900,389.29 28,156,977,599.07                 10.47 25,437,613,001.39


 2) Major financial indicators

     Major nancial indicators                                2021       2020                       YoY Change (%)            2019
     Basic earnings per share (RMB/share)                   0.6864     0.5753                                  19.31       0.4615
     Diluted earnings per share (RMB/share)                 0.6858     0.5728                                  19.73       0.4607
     Basic earnings per share after deduction of
                                                            0.6329     0.4964                                  27.50       0.4277
     extraordinary gains and losses (RMB/share)
     Weighted average return on net assets (%)               11.50      10.41    Increased by 1.09 percentage points          8.98
     Weighted average return on net assets after
                                                             10.60       8.98    Increased by 1.62 percentage points          8.32
     deduction of extraordinary gains and losses (%)


     Statement on major accounting data and nancial indicators within three years before the end of the Reporting Period
     □ Applicable √ N/A


VIII Differences in accounting data under domestic and foreign accounting standards

 1) Differences in net profit and net assets attributable to shareholders of the listed company disclosed in the financial
    statements according to international accounting standards (IFRS) and Chinese accounting standards (Chinese
    GAAP)
     □ Applicable √ N/A


 2) Differences in net profit and net assets attributable to shareholders of the listed company disclosed in the financial
    statements according to foreign accounting standards and Chinese accounting standards
     □ Applicable √ N/A


 3) Explanations on differences under domestic and foreign accounting standards:
     □ Applicable √ N/A




12
                                                                                                                             Annual Report
                                                                                                                                     2021


IX Major financial indicators in 2021 by quarter
                                                                                                                  Unit: Yuan Currency: RMB
                                                           1st quarter          2nd quarter               3rd quarter             4th quarter
                                                         (Jan. - Mar.)          (Apr.- Jun.)            (Jul. - Sept.)           (Oct. - Dec.)
    Revenues                                         4,144,871,763.27    3,690,500,511.39        4,098,276,714.19            3,970,039,277.74
    Net prot attributable to shareholders of
                                                      366,890,019.20      320,457,475.33              321,327,690.20          319,824,247.32
    the listed company
    Net prot attributable to Shareholders of
    the listed company after deducting the            335,022,033.02      262,870,294.41              321,676,905.90          305,428,138.24
    extraordinary gains or losses
    Net cash ow from operating activities             494,649,514.25      251,137,999.11              875,382,191.22          941,919,340.66


   Statement on dierences between quarterly data and the data disclosed in previous periodic reports
   □ Applicable √ N/A


X Items and amounts of extraordinary gains and losses
   √ Applicable □ N/A
                                                                                                                  Unit: Yuan Currency: RMB
    Item of extraordinary gains and losses                                                     2021                2020                 2019
    Gain or loss on disposal of non-current assets                                14,492,047.24         102,634,566.25           1,492,371.91
    Government grants recognized in prot or loss for the current period
    (excluding government grants that are closely related to the business
    of the Company and are provided in xed amount or quantity                    245,335,140.69         246,707,925.30        178,577,544.79
    continuously according to the applicable polices and standards of the
    country)
    Prot or loss on debt restructuring                                                         0.00        -298,617.11                   0.00
    Gains and losses on fair value changes incurred from nancial assets
    held for trading, derivative nancial assets, nancial liabilities held for
    trading and derivative nancial liabilities, and investment income on
    disposal of nancial assets held for trading, derivative nancial assets,
                                                                                   8,110,644.25          48,458,672.96         -12,515,352.16
    nancial liabilities held for trading, derivative nancial liabilities and
    other debt investments, except for
    eective hedging activities related to the ordinary operating business
    of the Company
    Reversal of impairment loss on accounts receivable and contract assets
                                                                                   1,013,650.67                          0        468,558.26
    tested for impairment individually
    Other non-operating income and expenses apart from the above items           -30,737,442.83         -22,794,516.25          -9,119,451.05
    Less: Eect of income tax                                                      39,580,260.30          51,541,134.41         22,788,289.61
    Eect of minority equity (after tax)                                           95,131,719.24         169,407,317.63         70,628,629.07
    Total                                                                        103,502,060.48         153,759,579.11         65,486,753.07


   explanations for classifying items of extraordinary gains and losses dened in the Explanatory Announcement No. 1 for Public
   Company Information Disclosures –Non-recurring Profits and Losses - Extraordinary gains and losses as items of recurring
   prot or loss
   □ Applicable √ N/A




                                                                                                                                            13
XI Items measured at fair value
     √ Applicable □ N/A
                                                                                                    Unit: Yuan Currency: RMB
                                                                                     Change during the     Eect on current
     Item                                     Beginning balance    Ending balance
                                                                                                period      Prots & losses
     Financial assets held for trading           28,328,748.72     184,638,344.31      156,309,595.59        10,674,950.50
     Other equity instrument investments       1,576,391,663.13   1,408,882,377.42    -167,509,285.71        37,114,395.95
     Financial liabilities held for trading             212.07         143,302.24          143,090.17          -143,090.17
     Total                                     1,604,720,623.92   1,593,664,023.97      -11,056,599.95       47,646,256.28


XII Others
     □ Applicable √ N/A




14
   Chapter 3
   Management Discussion and Analysis


I Discussion and analysis of business operation

   In 2021, the rst year of the 14th Five-Year Plan period, the ght against COVID-19 on the global scale remained challenging,
   and the external environment was becoming increasingly complicated and uncertain. In this context, China pursued economic
   development while ensuring stability and deepened reform of the medical and health care systems. The pharmaceutical
   industry was accelerating its pace in upgrading and innovation, and yielded new results in pursuing high quality development.
   Facing the complex and volatile market environment, and guided by the vision of“Attentively developing high-quality
   medicines and innovative medicines”and the core values of“Putting People First, Valuing Workmanship and Quality,
   Pursuing Innovation and Truth, Promoting Cooperation and Sharing”, the Company achieved sustained and stable growth
   by focusing on its principal business, fully leveraging its comprehensive strength, increasing input in R&D to improve its
   innovative capability, and adjusting the product structure in a quicker pace to adapt to the in-depth reform and innovation of
   the marketing system.


(1) Focusing on innovative medicines and high-barrier complex preparations to promote innovation and upgrading for
    sustainable development
   Driven by technical innovation, the Company has been concentrating on developing innovative medicines and high-barrier
   complex preparations to meet the needs of patients. While continuing to promote original inhalation drugs, sustained-release
   microspheres, antibodies technology and other platforms with technical strength, the Company has been committed to
   developing technical platforms for new complex injections represented by micro/nano injection, and has entered a new stage
   of product structure optimization. During the Reporting Period, the Company made a major headway in developing multiple
   innovative medicines, and sped up the innovation process. It completed phase III clinical study and production application for
   Tobramycin Solution for Inhalation ( 妥 布 霉 素 吸 入 溶 液 ) and Triptorelin Acetate Microspheres for Injection ( 注 射 用 醋 酸
   曲 普 瑞 林 微 球 ) (1-month sustained release). Overseas phase III clinical study of Recombinant SARS-CoV-2 Fusion Protein
   Vaccine ( 重组新型冠状病毒融合蛋白疫苗 ) (“V-01”) was advancing smoothly. Formoterol Fumarate Inhalation Aerosol
   ( 富马酸福莫特罗吸入气雾剂 ), Mometasone Furoate and Formoterol Fumarate Dihydrate Inhalation Aerosol ( 莫米松福莫
   特罗吸入气雾剂 ), Aripiprazole Microspheres for Injection ( 注射用阿立哌唑微球 ), and Recombinant Anti-human IL-17A/
   F Humanized Monoclonal Antibody Injection ( 重组抗人 IL-17A/F 人源化单克隆抗体注射液 ) were currently under clinical
   study, and an approval for clinical study of Aclidinium Bromide Powder for Inhalation ( 阿 地 溴 铵 吸 入 粉 雾 剂 ), Triptorelin
   Pamoate Microspheres for Injection ( 注 射 用 双 羟 萘 酸 曲 普 瑞 林 微 球 ) (3-month sustained release) and Alarelin Acetate
   Microspheres for Injection ( 注射用丙氨瑞林微球 ) (1-month sustained release) was obtained.

   While continuously strengthening independent innovation, the Company actively sought opportunities for frontier technology
   expansion and global product layout through cooperative development and licensing, among other means, to improve its
   capability for commercialization and integration. In 2021, Joincare Biopharmaceutical Research Institute signed a strategic
   cooperation agreement with Tencent Quantum Lab ( 腾 讯 量 子 实 验 室 ) to study Biosynthetic Gene Clusters (BGCs) from
   the prospective of synthetic biology with AI technology; Livzon Group completed introduction of multiple technologies,
   and completed IND application for a small-molecule antitumor drug (LZ001) developed in cooperation with Zhejiang TYK
   Medicines. A pre-IND application was submitted for a transdermal product Asenapine introduced with authorization by a
   German company LTS Lohmann Therapie-Systeme AG. At the same time, Livzon Group participated in the pre-A round
   equity investment of Beijing Infinite Intelligence Pharma and B round financing of Beijing Luzhu Biotechnology Co., Ltd.,
   which was conducive to further enriching the Company's industrial layout and empowering product pipeline. Moreover, the
   Company succeeded in exporting its products under research, with its R&D strength gradually recognized by overseas markets.
   In November 2021, Livzon MAB licensed the Recombinant Humanized Anti-PD-1 Monoclonal Antibody for Injection ( 注 射
   用重组人源化抗 PD-1 单克隆抗体 ) with proprietary intellectual property rights to Bright Peak Therapeutics, Inc., on a non-
   exclusive basis for development of novel PD-1-targeted immune cytokines (PD-1 ICs) ( 新型 PD-1 靶向免疫细胞因子 ).




                                                                                                                                  15
 (2) Building a diversified marketing model to strengthen brand promotion
     In 2021, the marketing teams of prescription medicines actively implemented the sales plans and mainly completed the
     following key tasks: strengthening product and brand promotion, integrating terminal resources, focusing on appraisal of
     hospitals at above grade II, and enhancing the coverage of core brands and fulllment rate of evaluation indicators. During the
     Reporting Period, the hospital coverage rate of key products continued to rise, and the overall sales revenue of prescription
     medicines showed a remarkable increase compared with the previous period; strengthening professional marketing and fine
     management, constantly improving the marketing teams of the respiratory and psychiatric departments to promote the rapid
     growth of respiratory and psychiatric products; continuously promoting digital marketing, such as using new media like
     TikTok and WeChat to conduct online marketing and popularize knowledge on disease management so as to improve the
     Company's brand image; continuing to carry out evidence marketing, and maintain close communication with domestic and
     international academic communities. Thanks to the eorts, Levosalbutamol Hydrochloride Nebuliser Solution ( 盐 酸 左 沙 丁
     胺醇雾化吸入溶液 ), Ilaprazole series ( 艾普拉唑系列 ) and Perospirone Hydrochloride Tablets ( 盐酸哌罗匹隆片 ), among
     others, were incorporated into a number of core guides or clinical consensus, and the clinical and pharmacoeconomic study for
     key products went on smoothly, boosting continuous growth of products; actively following up the implementation of policies
     on national medical reform, and including four products to the fifth batch of centralized drug procurement organized by the
     State; achieving success in negotiation over keeping Ilaprazole Sodium for injection ( 注 射 用 艾 普 拉 唑 钠 ) in the national
     reimbursement drug list, to reduce its price, improve its accessibility to patients, and expand the number of patients beneting
     from it.

     Actively exploring overseas markets remained the focus for API marketing this year. Affected by the spread of the pandemic
     worldwide, the demand for high-end antibiotics was increasing. Seizing the opportunity, the Company further improved its
     competitiveness and shares of high-end antibiotic products such as Meropenem ( 美 罗 培 南 ), Vancomycin ( 万 古 霉 素 ) and
     Teicoplanin ( 替考拉宁 ) in overseas markets. Through conducting in-depth cooperation with strategic customers, the Company
     actively explored overseas markets to maintain the current high market shares of intermediates; through strengthening
     cooperation with major animal heath companies around the world, the Company increased the market shares of high-end pet
     drugs in many regions, and the market development for new products was progressing smoothly.


 (3) Attaching equal importance to quality and efficiency, and accelerating the pace of internationalization
     Adhering to the concept that quality, safety and environmental protection are the lifeline, the Company conducted
     systematic control of quality and safety risks, improved the management mechanism, and increased investment in safety and
     environmental protection, to ensure production safety and stable quality of drugs. At the same time, the Company continued
     to promote lean production and technical innovation of the production process. Through process optimization, the yield of key
     products was improved and the costs went down against the backdrop of continued rise of commodity prices and increased
     pressure from procurement costs of raw materials. While constantly consolidating the foundation for environmental protection
     and safety, improving the quality of existing products, optimizing the production process, and promoting the normalization
     of GMP, all production enterprises actively applied for international certification. The internationalization process was
     further accelerated. With respect to preparations, the Company strengthened the access and promotion of respiratory, assisted
     reproduction, antifungal, antiviral and Gastroenterology products in Pakistan, Indonesia, the Philippines and other countries
     and regions. In 2021, Joincare Haibin's production line for Compound Ipratropium Bromide Solution for Inhalation ( 复 方 异
     丙托溴铵吸入溶液 ) passed GMP certication in the Philippines; Livzon's Kanamycin for Injection ( 丽珠卡那霉素注射液 )
     passed international certication and obtained a WHO pre-certication qualication certicate and special import approval in
     Indonesia. With respect to APIs, In 2021, three products were registered internationally which mainly include: Daptomycin ( 达
     托 霉 素 ) was approved for registration in Portugal, Japan, India, Singapore, Brazil and South Africa; Ceftriaxone sodium ( 头
     孢曲松钠 ) was approved for registration in Pakistan, East Africa, Colombia and Vietnam.




16
                                                                                                                 Annual Report
                                                                                                                         2021


(4) Optimizing the management structure and improving the overall operating efficiency
    During the Reporting Period, the Company further improved the Group's organizational structure and institutional setting,
    optimized the management structure, completed the establishment of five management centers through resource integration,
    and realized the improvement of management efficiency. In order to improve the overall operating efficiency and the risk
    control ability of the Group, the Company formulated the Detailed Rules for Standardized Operation and Management of
    Subsidiaries to further standardize and improve internal control operation and management; improved the management by
    objective (MBO) system with OKRs and KPIs in parallel, with full cooperation and support from all functional departments
    to provide strong services and guarantee for R&D, production and marketing; attached great importance to the building of a
    talent echelon, implemented the A/B role working mechanism, enhanced the working capability of employees, and continued
    to introduce high-end talents while strengthening identification, training and promotion of internal talents, to ensure stability
    of the core talent team; and improved cultural infrastructure, and constantly optimized the working environment and living
    facilities for employees, to enhance their sense of happiness and enterprise identity so as to achieve greater cohesiveness and
    anity in the workplace.


(5) Strengthening social responsibility management to boost high-quality development
   In 2021, taking into account the industrial characteristics and the overall strategic goals of the State, the Company formulated
   the“Energy Conservation and Emission Reduction Targets 2021-2025”, urging all production enterprises to carry out
   fine management of resources and energy consumption, and putting forward higher requirements for green production and
   sustainable development of the Company. While promoting the development of principal business, the Company further
   fullled its social responsibilities by actively participating in social welfare undertakings. Since the end of 2018, the Company
   has been cooperating with Livzon Group on the“Inclusive Chronic Disease Prevention and Treatment Public Welfare Project”
   to deliver urgently needed drugs to middle-aged and elderly patients with chronic diseases in Sichuan, Shanxi, Gansu, Jilin,
   Xizang, Henan, Anhui, Hunan and Jiangxi provinces. Moreover, the Company donated RMB 10 million in cash and RMB
   10 million worth of drugs through Chinese Red Cross Foundation to aid disease prevention and post-disaster recovery and
   reconstruction in ood-hit areas in Henan.


II Overview on the industry in which the Company operates during the Reporting Period

    On 30 January 2022, the“14th Five-Year Plan for the Development of Pharmaceutical Industry in China”(hereinafter referred
    to as the“Plan”) was jointly released by the Ministry of Industry and Information Technology, National Development and
    Reform Commission, Ministry of Science and Technology, Ministry of Commerce, National Health Commission, Ministry
    of Emergency Management, National Healthcare Security Administration, National Medical Products Administration, and
    National Administration of Traditional Chinese Medicine. The Plan noted that the pharmaceutical industry is a strategic
    industry vital to the national economy, people's livelihood, economic development and national security, and an important
    foundation for the building of Healthy China. The Plan also clarified the development goals and safeguard measures for the
    pharmaceutical industry in the next five years. Pursuant to the Plan, the average annual growth rate of operating revenue
    and total profit should be above 8%. The Plan underscores the importance of product innovation, manufacturing upgrade
    and international development, and encourages enterprises to tap into the global market, vigorously promote the R&D of
    innovative products, and improve industrial technologies, placing higher requirements for the innovation-driven transformation
    and high-quality development of China's pharmaceutical industry.

    Data of National Bureau of Statistics shows that in 2021, enterprises in the pharmaceutical manufacturing industry above
    designated scale in China have realized Revenues of RMB2,928.85 billion, representing a year-on-year increase of 20.1%;
    operating costs of RMB1,560.68 billion, representing a year-on-year increase of 12.7%; total profits of RMB627.14 billion,
    representing a year-on-year increase of 77.9% or an increase of 65.1 percentage points in growth rate as compared with
    the same period of last year, 43.6 percentage points higher than the overall level of domestic industrial enterprises above
    designated scale in the same period.




                                                                                                                                  17
III Overview on the main businesses of the Company during the Reporting Period

 (I) Principal businesses and products of the Company
     The Company was primarily engaged in the R&D, production and sale of pharmaceutical products and health care products.
     Pursuant to the Guidelines for the Industry Classication of Listed Companies (2012 Revision) issued by CSRC, the Company
     operated in the pharmaceutical manufacturing industry (C27).

     At present, the business scope of the Company covers chemical drug preparation products, traditional Chinese drug preparation
     products, chemical active pharmaceutical ingredients (APIs) and intermediates, diagnostic reagents and equipment, and
     health care products, etc. The comprehensive product series and mix provide larger market and growth opportunities for the
     Company. Main products of the Company are as follows:


        Product
                    Treatment Field                                               Main Products
         Type




                                       Levosalbutamol Hydrochloride Nebuliser Solution            Budesonide Suspension for Inhalation
                                                         ( 丽舒同 )                                             ( 雾舒 )
                      Respiration



       Chemical
         drug
      preparation
       products
                                                                                            Compound Ipratropium Bromide Solution for
                                         Ipratropium Bromide Solution for Inhalation
                                                                                                               Inhalation
                                                         ( 丽雾安 )
                                                                                                               ( 舒坦琳 )




                    Gastroenterology



                                              Ilaprazole Enteric-Coated Tablets                     (Ilaprazole Sodium for Injection)
                                                        (壹丽安)                                            (壹丽安)




18
                                                                                                                    Annual Report
                                                                                                                            2021


 Product
              Treatment Field                                              Main Products
  Type




              Gastroenterology


                                 Bismuth Potassium Citrate Tablets/Tinidazole
                                                                                           Bismuth Potassium Citrate Tablets
                                        Tablets/Clarithromycin Tablets
                                                                                                     ( 丽珠得乐 )
                                                ( 丽珠维三联 )




               Anti-infection


Chemical
                                           Meropenem for Injection                             Voriconazole for Injection
   drug
                                                    ( 倍能 )                                           ( 丽福康 )
preparation
 products



               Gonadotropic
                 hormones


                                 Leuprorelin Acetate Microspheres for Injection               Urofollitropin for Injection
                                                    ( 贝依 )                                           ( 丽申宝 )




                 Psychiatry



                                         Fluvoxamine Maleate Tablets                       Perospirone Hydrochloride Tablets
                                                   ( 瑞必乐 )                                          ( 康尔汀 )



Traditional
 Chinese
                Anti-tumor,
   drug
                   Cold
preparation
 products
                                             Anti-tumor medicine                                    Cold medicine
                                           Shenqi Fuzheng Injection                               Anti-viral Granules




                                                                                                                                19
                      Treatment
      Product Type                                                                   Main Products
                        Field
        Chemical
                                    7-ACA, D-7ACA, Meropenem Trihydrate, Imipenem and Cilastatin Sodium, Phenylalanine, Daptomycin, Vancomycin
        APIs and          /
                                                                 Hydrochloride, Mevastatin, Acarbose, Lincomycin, etc.
      intermediates




       Diagnostic
      reagents and        /
       equipment

                                                                                               Diagnostic Kit for IgM / IgG Antibody to Coronavirus
                                          Autoimmunity multiple detection platform
                                                                                                           (SARS-CoV-2) (Lateral Flow)




       Healthcare
                          /
        products



                                                 Jingxin Menocare Essence                                  Eagle's American Ginseng Tea




 (II) Business model of the Company
     With the stable operation and rapid development over the years, the Company has become a comprehensive pharmaceutical
     group company that is driven by scientific research and innovation and integrates the R&D, production, sale and service of
     pharmaceutical and health care products. It has complete systems of R&D, procurement, production and sale. Main business
     models of the Company are as follows:

 1. R&D model

     Taking independent R&D as the mainstay and combining external introduction and cooperative development, the Company
     has been paying attention to the cutting-edge technology and unfulfilled clinical demand, with efforts focused on innovative
     medicines and high-barrier complex drug preparations, and has established an efficient R&D innovation management model.
     In terms of independent innovation, the Company has diversied, multi-level R&D organizations with mature R&D teams for
     chemical drug preparation products, traditional Chinese drug preparation products, biological drugs, APIs, diagnostic reagents
     and health care products. Based on technology platform construction, the Company has built a clear product R&D pipeline
     centering on key areas such as respiration, tumor immunity and psychiatry. In terms of cooperative innovation, the Company
     has launched technical cooperation with domestic and foreign scientific research institutions by way of commissioned
     development or cooperative development, and introduced new technologies and products through technology transfer or
     licensing to implement industrial transformation, so as to shorten the time for product development and research and reduce the
     risk of development to a certain extent.




20
                                                                                                                       Annual Report
                                                                                                                               2021


2. Procurement model

    In terms of procurement, the Company pays strict attention to effectiveness, quality and cost of procurement and has
    established long-term and stable partnership with many suppliers. Active pharmaceutical ingredients, supplementary materials,
    and packaging materials were purchased and stocked up by manufacturers according to production schedules. The Company
    has developed strict quality standards and procurement management systems and required subordinate manufacturers to make
    procurements in accordance with the GMP. Meanwhile, the Company established long-term strategic partnerships with bulk
    material suppliers, and strengthened the management of supply quality and cost control based on strict quality standards. The
    Company has established an internal evaluation system and les of market prices so as to promptly master market information
    for procurement through comparisons of quality and price.

3. Production model

    In terms of production, the Company adopts the principle of market demand-oriented approach paying attention to real
    market demand. Specifically, the Sales Department of the Company investigated market demands, made sales plans, and
    comprehensively considered factors such as the product inventory quantity and capacity of production lines of the Company so as
    to determine the monthly production quantities and specications. Moreover, the purchase orders of raw materials are determined
    according to the production schedule and the inventory levels of raw materials. The final production plans are issued upon
    approval of the management of the Company and implemented by the Production Technology Department of the Company.

    The Company carried out production in strict accordance with the GMP. The Company and its affiliates have established a
    sound quality management system and implemented the qualified person system. In terms of quality control, the Company
    established a strict and sound production quality assurance system, and was geared to international standards and subject to
    international certication while in compliance with national standards. The Company conducted annual GMP self-inspection,
    ISO9001 internal and external audits, and was subject to various external audits. It actively pursued the internationally
    advanced GMP management, and implemented whole-process quality control over supplier selection, audit, incoming material
    inspection, production process, product release from factory, and market tracking with good system operation.

4. Sales model

(1) Drug preparation products

    End customers of drug preparation products of the Company are mainly hospitals, clinics, and retail pharmacies. In line
    with the pharmaceutical industry practice and the sales model of most peers in the industry, the Company has conducted
    sales of drug preparation products through drug distribution enterprises. The Company carried out selection and centralized
    management of qualified drug distribution enterprises (with Drug Supply Certificate, GSP Certification, etc.) according to
    their distribution capability, market familiarity, financial strength, credit record, and operation scale. General sales process:
    After end customers place purchase orders to distribution enterprises, drug distribution enterprises will send those orders to the
    Company according to their inventories, distribution agreements and conditions; then, the Group will deliver products to drug
    distribution enterprises and do the revenues recognitions.

(2) APIs and intermediates

    Main target customers of APIs are large pharmaceutical manufacturers. The selling prices are determined based on a set of
    comprehensive factors such as costs of production, inventory levels, industry rivalry and market conditions. Specic pricing method:
    The detailed process of price determination are as follows: The sales and marketing department conduct weekly or bi-weekly
    meetings to analyze the current market conditions and the trends and drivers of prices; the selling prices are determined based on a set
    of comprehensive factors such as costs of production, inventory levels, industry rivalry and market conditions; the selling prices will
    be eective once are reported by the managers of the sales department to our management team and get approvals.

    Specific sales methods of APIs include: 1) Domestic market: The Company directly signs product sales contracts with large
    manufacturers to directly sell products to customers. Meanwhile, the Company also sells products through distributors. 2)
    Foreign market: The Company directly sells products in the foreign market and also sells products through distributors in
    areas with high market and political risks. At present, products of the Company are mainly exported to nearly 40 countries and
    regions in Asia, Europe, North America, and Africa.


                                                                                                                                         21
 (3) Diagnostic reagents and equipment

     Diagnostic reagents and equipment sold by the Company both in-house manufactured and imported. Main end customers are
     hospitals, centers for disease control and prevention, and health departments. The Company mainly sells those products in
     combination with direct sales and sales through drug distribution enterprises.

     The Company has an experienced sales team responsible for the sales of diagnostic reagents and equipment and provision of
     marketing support for some drug distribution enterprises. The Company carried out selection and centralized management of
     qualified drug distribution enterprises (with Drug Supply Certificate, GSP Certification, etc.) according to their distribution
     capability, market familiarity, nancial strength, credit record, and operation scale.

 (4) Health care products

     The sales model of health care products is mainly distributor management model. Product promotion, price control, and
     channel carding are managed and improved with the distributor distribution channel and terminal coverage capability. At
     present, the Company has set up 27 provincial branches and 107 subordinate offices across China and maintained long-term
     partnership with distributors with better area coverage capability for stable strategic alliance and common development. The
     Company has cooperated with about 103 first-level/primary distributors in total, including 78 businesses in drug production
     line and more than 25 businesses in food production line with more than 150,000 subordinate secondary businesses and
     terminal businesses in drug and food production lines. Products are well managed and promoted through the tiered marketing
     channel. In addition to the traditional distribution management model, the Company realizes common development through
     coordinated marketing in E-commerce channel.


(III) Industry status of the Company
     Through years of development, the Company has become a comprehensive pharmaceutical enterprise covering multiple areas
     including chemical drug preparation products, chemical APIs and intermediates, traditional Chinese drug preparation products,
     diagnostic reagents and equipment, health care products, etc. Chemical drug preparation products are the largest revenue
     generator of the Company, among which gastroenterological products, anti-infective products and gonadotropic hormones
     products are traditional competitive products of the Company, with key products securing a long-term position in national
     drug preparation market, and respiratory and psychiatrical products have been the focus of the Company, with key products
     maintaining a strong sales growth momentum.

     During the Reporting Period, the Company, with solid strength in R&D and production and steady marketing presence, ranked
     Top 9 in“2020 Annual Ranking of Top 100 Chinese Chemical Drug Enterprises”under“2020 Annual Ranking of Top 100
     Enterprises in Pharmaceutical Industry in China”of menet.com.cn.


(IV) Performance drivers in the Reporting Period
     In 2021, the COVID-19 pandemic was basically and effectively controlled in China, and medical order was gradually
     restored to normal. The Company actively implemented sales deployment, strengthened market promotion, reinforced
     sales specialization and delicacy management, and ensured steady growth of overall performance of the Company during
     the Reporting Period. During the Reporting Period, sales of main varieties in key specialist areas, especially in fileds of
     respiratory, Gastroenterology, gonadotropic hormonesof the Company kept steady growth, and contribution of sales revenue of
     key preparation products to overall revenues was continuously improved.

     Meanwhile, sales of API segment realized steady growth after resources integration, adjustment of product mix, reinforcement
     of international certication and other measures taken by the Company.




22
                                                                                                              Annual Report
                                                                                                                      2021


IV Analysis of core competitive strengths during the Reporting Period
   √ Applicable □ N/A


1. Diversied product structure, constantly upgraded product matrix and obvious brand advantage

   Since its foundation, the Company has been dedicated to the production and operation of pharmaceutical and health products,
   and has built a successful brand image and won wide recognition in the market with premium product quality and market
   service. Products of the Company cover biologics, prescription drug preparations, APIs, health products, OTC drugs,
   diagnostic reagents and equipment, enabling the Company to establish an advantageous market position in a number of
   therapeutic elds such as respiration, anti-infection, assisted reproduction, gastroenterology, psychiatry, and tumor immunity.
   Many brands of series products under the Company have made the Company widely recognized and gain brand advantages.
   In particular, in recent years, the Group has successfully removed the barriers in R&D, approval and production of inhalation
   preparations, and launched competitive products such as“Shutanlin ( 舒 坦 琳 )”,“Lishutong ( 丽 舒 同 )”and“Wushu ( 雾
   舒 )”in succession, breaking through the monopoly in the international market and marking a milestone in the history of
   development of inhalation preparations in China.

2. R&D innovation strength

   Under the strategy of developing both innovative preparations and high-barrier complex preparations, and bearing in mind the
   unsatised clinical demands, the Company has been committed to the development of technical platforms for inhalation drugs,
   antibodies, sustained-release microspheres and milk corpuscles through increasing R&D investment, actively introducing
   domestic and foreign senior experts and innovative talents, and forming overseas strategic alliances, to continuously enhance
   its R&D competitiveness. At present, with diversied and multi-level R&D institutions, the Company boasts strong capability
   and internationally advanced R&D concepts in the fields of chemical and traditional Chinese drug preparation products,
   biological drugs, diagnostic reagents, health products and over-the-counter (OTC) drugs, and has formed a clear layout of
   product lines in the elds of respiration, assisted reproduction, digestion, psychiatry and nerve and tumor immunity, etc.

   The Company adopted a strategy of“competitive dierentiation”in the layout and management of R&D pipeline, focusing on
   both innovation and success rate. On the one hand, the Company took practical measures to accelerate the R&D and launch of
   modified innovative medicines, to constantly improve the sustainable profitability of product matrix; and on the other hand,
   firmly and steadily deployed cutting-edge technologies from a long-term perspective, such as AI drug molecular design and
   synthetic biology, to empower the innovation, success rate and eciency of the Group's R&D pipeline.

3. Improved terminal competitive strength through continuous marketing reform and innovation

   Through continuous marketing reform and innovation, the sales teams of the Company became more independent, competitive
   and capable, and maintained a good cooperative relationship with dealers at all levels through active and frequent interaction
   with them. Joincare has adopted the new marketing model of streamline administration and institute decentralization to
   enhance independent sales and decision-making abilities of contractual sellers, optimized resource allocation of personnel,
   variety, terminal and policy while arousing the enthusiasm and motivation of marketing personnel, expanded product
   promotion and coverage, and achieved eective growth of operating income.

   Corporate value added by innovation of marketing model. In the future, the health industry in China will tend to combine
   the emerging Internet marketing with the traditional industry via the Internet, especially mobile Internet to improve sales
   conversion rate and enhance customer and consumer stickiness. Under the new digital marketing mode, Joincare strives
   to empower all links including education, screening, diagnosis, treatment and medication monitoring, form a closed-loop
   consisting of doctors, hospitals, patients and drug companies, and explore the external huge market of chronic disease
   management with private trac, so as to realize real-time interaction between consumers and brands, and inject new vitality to
   commercialization of the Company.




                                                                                                                              23
 4. Enhanced Talent Teams

     The Company has a stable, visionary and experienced, results-oriented management team and an outstanding talent team.
     Outstanding leaders are the key to the Company's rapid development. The founder and the core management team of Joincare
     have long-term work experience and rich professional knowledge in the pharmaceutical industry, and have rich experience,
     outstanding leadership, vision and ambition in the eld under their management. Joincare has upheld the core value of“Putting
     People First, Valuing Workmanship and Quality, Pursuing Innovation and Truth, Promoting Cooperation and Sharing”and
     laid emphasis on talent training to build a diversified reserve of talents with global vision, advanced knowledge, strong
     implementation capability and sense of self-reliance. Driven by the corporate culture of pursuing excellence, the talent
     team works diligently and conscientiously to achieve the strategic goals and vision of the enterprise through teamwork and
     collaboration.


 V Overview of business operations during the Reporting Period

     During the Reporting Period, Joincare realized total revenues of RMB 15,904 million, up approximately 17.62% compared
     with the same period last year; realized a net profit attributable to shareholders of listed companies of RMB 1,328 million,
     representing a year-on-year increase of approximately 18.57%; and realized a net profit attributable to shareholders of listed
     companies after deduction of the extraordinary gains and losses of RMB 1,225 million, representing a year-on-year increase of
     approximately 26.72%. Operation results of our main business segments are as follows:


 (1) Livzon Group (excluding Livzon MAB)
     As at the end of the Reporting Period, the Company directly and indirectly held 44.66% of equity interest in Livzon Group
     (000513.SZ, 01513.HK). During the Reporting Period, Livzon Group (excluding Livzon MAB) realized revenues of RMB
     12,021 million, representing a year-on-year increase of approximately 14.27%; and realized a net prot of approximately RMB
     888 million attributable to shareholders of the Company. For operation and financial results of Livzon Group, please refer to
     the 2021 Annual Report of Livzon Pharmaceutical Group Inc.


 (2) Livzon MAB
     As at the end of the Reporting Period, the equity interest directly and indirectly held by the Company in Livzon MAB was
     55.86%, and the amount affecting the Company's net profit attributable to the parent company for the current period was
     approximately RMB -211 million.

     During the Reporting Period, Livzon MAB focused on promoting the clinical study and commercialization of the Recombinant
     SARS-CoV-2 Fusion Protein Vaccine ( 重 组 新 型 冠 状 病 毒 融 合 蛋 白 疫 苗 ) (“V-01”) project. The results of Phase I/II
     clinical trials of V-01 showed that the vaccine had excellent safety and immunogenicity. Phase III clinical trials were carried
     out overseas in a comprehensive manner. Phase III clinical trials of the basic immunization regimen were conducted in the
     Philippines, Indonesia and Russia, and phase III clinical trials of inactivated sequential immunization as a booster shot were
     conducted in Pakistan and Malaysia. The vaccine commercialization workshop had been completed and put into use. Phase
     III clinical trial of V-01, the Company's first product undergoing global multi-center clinical trials was advancing smoothly,
     providing resources and experience for subsequent internationalization of Company's innovative medicines and multi-center
     clinical trials of more drugs in terms of organizational management, partnership, team capabilities and registration application.

     On the other hand, Livzon MAB continues to focus on new molecules, new targets and differentiated molecular designs in
     the fields of oncology, autoimmune diseases and assisted reproduction. During the Reporting Period, the following projects
     of biologics have achieved phase progress in R&D: Recombinant Human Choriogonadotropin alfa for Injection ( 注 射 用 重 组
     人 绒 促 性 素 ) was approved for market launch as the rst domestic generic drug and has started sales; the BLA application of
     Tocilizumab Solution for Injection ( 托珠单抗注射液 ) (i.e. Recombinant Humanized Anti-human IL-6R Monoclonal Antibody
     Solution for Injection ( 重 组 人 源 化 抗 人 IL-6R 单 克 隆 抗 体 注 射 液 ) was accepted by CDE (Center for Drug Evaluation
     under the National Medical Products Administration); Recombinant anti-human IL-17A/F Humanized Monoclonal Antibody




24
                                                                                                                   Annual Report
                                                                                                                           2021


    Injection ( 重组抗人 IL-17A/F 人源化单克隆抗体注射液 ) completed enrollment of the Ib clinical trial; Recombinant Human
    Follitropin Alfa Solution for Injection ( 重组人促卵泡激素注射液 ) was approved for clinical trials, and has initiated the phase
    I clinical studies. During the Reporting Period, Livzon MAB and Bright Peak Therapeutics, Inc., an American company, signed
    a licensing cooperation agreement on the Recombinant Humanized Anti-PD-1 Monoclonal Antibody for Injection ( 注 射 用 重
    组人源化抗 PD-1 单克隆抗体 ) project, which will provide more opportunities for further commercialization in future.


(3) Joincare (excluding Livzon Group and Livzon MAB)
    During the Reporting Period, Joincare (excluding Livzon Group and Livzon MAB) realized revenues of RMB 4,129 million,
    up about 23.41% compared with the same period last year; and realized a net profit attributable to shareholders of listed
    companies of RMB 650 million, a year-on-year increase of approximately 45.09%. Joincare realized a net profit attributable
    to Shareholders of the listed company after deducting the extraordinary gains and losses of RMB 618 million, representing a
    year-on-year increase of approximately 44.27%. Key results of the main therapeutic elds and core products are as follows:

① Prescription medicines

   During the Reporting Period, Joincare (excluding Livzon Group and Livzon MAB) realized sales revenues of RMB
   1,789million from prescription drug segment, representing a year-on-year increase of approximately 55%. Among which,
   the sales reveunes and year-on-year change of key therapeutic areas are as follows: the revenues genereated from the field
   of anti-infection totaled 1,192 million, repreenting a year-on-year increase of 12%; the revenues genereated from the filed of
   respiratory totaled 577 million, representing a year-on-year increase of 6.58 times.

    In 2021, the Company continued to accelerate construction of the national sales team in respiratory line, established a three-
    level fine marketing development system of regional manager, provincial manager, and development manager, actively took
    various measures to speed up the development of key products in hospitals: 1. Enhanced the coverage and fulfillment rate
    of evaluation indicators; the development speed of respiratory variety was obviously accelerated; more than 4,000 hospitals
    above grade II were developed; 2. Realized rapid coverage and sales growth of the variety by taking the opportunity that
    Levosalbutamol Hydrochloride Nebuliser Solution ( 盐 酸 左 沙 丁 胺 醇 雾 化 吸 入 溶 液 ) was included in the list of drugs for
    negotiation led by National Healthcare Security Administration; 3. Continued to advance the construction of digital marketing
    platforms, launched a phenomenal public welfare campaign titled“who has the strongest lung”on TikTok and promoted
    knowledge on respiratory disease on multiple platforms, marking a new starting point for digital marketing of prescription
    medicines; 4. The three inhalation preparation varieties of Budesonide Suspension for Inhalation ( 吸 入 用 布 地 奈 德 混 悬 液 ),
    Ipratropium Bromide Solution for Inhalation ( 吸 入 用 异 丙 托 溴 铵 溶 液 ), and Compound Ipratropium Bromide Solution for
    Inhalation ( 吸 入 用 复 方 异 丙 托 溴 铵 溶 液 ) were selected into the fth batch of centralized drug procurement organized by
    the State, contributing to rapidly opening up the domestic sales market and improving market share for inhalation preparation
    products of the Company.

② APIs and intermediates

    During the Reporting Period, Joincare (excluding Livzon Group and Livzon MAB) realized revenues of RMB 2,034million
    from APIs and intermediates, representing a year-on-year increase of approximately 11%.

    During the Reporting Period, in the API segment, Joincare continued to strengthen safety and environmental protection and
    drive lean production. Production capacity and yield of key products were improved steadily through further enhancement
    of technical innovation of the production process. In terms of marketing, both the sales volume and prices of the Company's
    key products 7-ACA and Meropenem Trihydrate ( 美 罗 培 南 混 粉 ) increased and remained at high levels in 2021, due to the
    continuous rise of commodity prices, the rising costs of raw materials and energy, the impact of pandemic and production
    restriction for environmental protection. On the other hand, the Company achieved stable sales growth through precise
    strategic layout, strengthening in-depth cooperation with strategic customers, and actively expanding domestic and foreign
    markets. In particular, the sales of Meropenem Trihydrate ( 美 罗 培 南 混 粉 ) continued to go up under the catalysis of overseas
    pandemic situation, driving the export share to a new high.




                                                                                                                                    25
     One of the key tasks of the Company this year is to strengthen R&D innovation of APIs. The Company established Joincare
     Biopharmaceutical Research Institute at the end of 2020 to focus on green pharmaceutical intermediates, enzymes used in the
     pharmaceutical industry, and biochemical APIs. At present, construction of the Research Institute goes well. The Research
     Institute has successfully introduced 8 doctors and 14 masters, successively established 6 R&D platforms of breeding
     of industrial strains, synthetic biology, biocatalysis, fermentation amplification, product extraction, and drug synthesis
     according to demands of the technical and industrial chain, and focused on development and research in improvement of the
     production capacity for industrial strains, and fermentation and extraction of natural products for drugs. In early 2021, Joincare
     Biopharmaceutical Research Institute signed a strategic cooperation agreement with Tencent Quantum Lab ( 腾讯量子实验室 )
     to drive the application of quantum computing + AI in research fields of microbial synthetic biology and relevant drugs, and
     conduct research on sequence prediction and metabolic pathway optimization of genome gene clusters and functional elements
     with AI technology.

 ③ Health care products and OTC drugs

     During the Reporting Period, Joincare (excluding Livzon Group and Livzon MAB) realized revenues of RMB 289 million
     from health products and OTC sector, representing a year-on-year decrease of approximately 12%.

     In 2021, due to the impact of external environment such as the lingering pandemic, natural disasters in key target provinces
     and medical insurance policies of the State, the customer flow of offline pharmacies and shops, which were the mainstream
     channels for the Company's healthcare products, declined sharply, affecting the offline sales performance. Joincare quickly
     adjusted the marketing strategy for health products in Q3 2021, by focusing on online digital marketing and increasing
     exposure on TikTok and Xiaohongshu platforms to improve the brand reputation and product visibility. At the same time, being
     customer-centered, Joincare enhanced the proportion of online sales channels to promote the sale of key products through
     content marketing to innovate trac referral for e-commerce platforms and increasing investment in festivals.


 (I) Analysis of principal business
 1. Analysis of changes in statement of income and statement of cash ows items
                                                                                                             Unit: Yuan Currency: RMB
                                                                                       Amount in same period
     Item                                             Amount in current period                                           Change (%)
                                                                                                  of last year
     Revenues                                                15,903,688,266.59              13,521,605,768.20                   17.62
     Operating costs                                          5,716,293,887.58                4,874,186,898.05                  17.28
     Selling expenses                                         5,026,812,145.41                3,940,337,105.29                  27.57
     Administrative expenses                                    939,253,444.33                  950,827,562.47                  -1.22
     Financial expenses                                         -92,894,751.72                  -98,885,820.58                   N/A
     R&D expenses                                             1,397,131,273.33                1,071,711,981.95                  30.36
     Net cash ow from operating activities                    2,563,089,045.24                3,024,999,592.24                 -15.27
     Net cash ow from investing activities                   -1,964,157,731.17                 -500,320,691.78                   N/A
     Net cash ow from nancing activities                       -974,904,353.44               -1,238,212,948.15                   N/A


     Reasons for changes in R&D expenses: Mainly due to an increase in the number of R&D projects, as well as an expansion of
     R&D scale and investment.

     Reasons for changes in net cash ow from investing activities: Mainly due to the payment of consideration for the acquisition
     of equity interest in Tianjin Tongrentang Group Co., Ltd. ( 天津同仁堂集团股份有限公司 ) and the increase in investment for
     construction of new plants and workshops of some subsidiaries.

     Details of material changes in business type, components or source of prots during the current period

     □ Applicable √ N/A




26
                                                                                                                         Annual Report
                                                                                                                                 2021


2. Analysis of revenues and costs
   √ Applicable □ N/A

    During the Reporting Period, the Company realized revenues of 15,904 million, representing a YoY increase of 17.62%; the
    operating costs totaled 5,716 million, an increase of 17.28% over the same period of the previous year.

1) Composition of principal businesses by industry, product, region and sales model
                                                                                                                  Unit: Yuan Currency: RMB
                                                       Principal business by industry
                                                                                           YoY change     YoY change         YoY change in
                                                                        Gross prot
    Industry                    Operating revenues    Operating costs                      in operating   in operating         gross prot
                                                                        margin (%)
                                                                                          revenues (%)       costs (%)         margin (%)
                                                                                                                          Increased by 0.26
    Industrial and commercial   15,741,612,221.92    5,602,928,231.82         64.41              17.13          16.29
                                                                                                                          percentage points
                                                                                                                          Increased by 8.33
    Service industry                 5,012,626.61        1,774,064.30         64.61             -20.36         -35.34
                                                                                                                          percentage points
                                                        Principal business by product
                                                                                           YoY change     YoY change            YoY change
                                                                        Gross prot
    Product                     Operating revenues    Operating costs                      in operating   in operating        in gross prot
                                                                        margin (%)
                                                                                          revenues (%)       costs (%)           margin (%)
    Chemical drug preparation                                                                                             Increased by 0.90
                                 9,102,675,799.95    1,769,561,792.01         80.56              35.88          29.85
    products                                                                                                              percentage points
    Chemical APIs and                                                                                                     Decreased by 1.17
                                 4,690,255,375.73    3,184,889,165.53         32.10              19.20          21.28
    intermediates                                                                                                          percentage points
    Traditional Chinese drug                                                                                              Increased by 0.59
                                 1,109,344,037.45     295,328,306.33          73.38             -11.04         -12.96
    preparation products                                                                                                  percentage points
                                                                                                                         Decreased by 14.14
    Diagnostic reagents and
                                   723,917,736.81     319,168,131.72          55.91             -47.65         -22.94     percentage points
    equipment

                                                                                                                          Increased by 2.19
    Health care products           115,164,422.30      33,652,500.02          70.78             -20.80         -26.33
                                                                                                                          percentage points
                                                        Principal business by region
                                                                                           YoY change     YoY change         YoY change in
                                                                        Gross prot
    Region                      Operating revenues    Operating costs                      in operating   in operating         gross prot
                                                                        margin (%)
                                                                                          revenues (%)       costs (%)         margin (%)
                                                                                                                          Increased by 0.38
    Domestic                    13,175,044,906.28    3,837,751,076.40         70.87              22.16          20.60
                                                                                                                          percentage points
                                                                                                                          Decreased by 7.11
    Overseas                     2,571,579,942.25    1,766,951,219.72         31.29              -3.34           7.82
                                                                                                                          percentage points
                                                      Principal business by sales model
                                                                                           YoY change     YoY change         YoY change in
                                                                        Gross prot
    Sales model                 Operating revenues    Operating costs                      in operating   in operating         gross prot
                                                                        margin (%)
                                                                                          revenues (%)       costs (%)         margin (%)
                                                                                                                          Increased by 0.77
    Channel sales               10,702,994,671.61    2,302,249,214.15         78.49              17.01          12.96
                                                                                                                          percentage points
                                                                                                                          Decreased by 0.74
    Direct sales                 5,043,630,176.92    3,302,453,081.97         34.52              17.33          18.67
                                                                                                                           percentage points




                                                                                                                                         27
     Explanations on composition of principal businesses by industry, product, region and sales model

     During the Reporting Period, the Company realized operating revenues of 15,747 million representing a YOY 2,301 million
     increase in amount and a YOY 17.11% increase in percentage; the operating revenues of chemical drug preparation products
     achieved a YoY increase of 35.88% and the operating revenues of APIs and intermediates achieved a YoY increase of 19.20%.


     The growth of the Company's revenues from principal businesses mainly thanks to the Company's efforts in deepening
     marketing reform by sinking down to low tier markets and focusing on sales in key specialist areas. Sales of main varieties
     in key specialist areas kept steady growth, and contribution of sales revenue of key preparation products to overall revenues
     was continuously improved. In specic, Ilaprazole series (gastroenterological products), Leuprorelin Acetate Microspheres for
     Injection and Urofollitropin for Injection (gonadotropic hormones products) achieved high growth year-on-year. Budesonide
     Suspension for Inhalation, Levosalbutamol Hydrochloride Nebuliser Solution and other series recorded a gradual increase
     in sales with a remarkable overall growth rate. Meanwhile, the sales volume of the API segment also rose steadily through
     consolidating resources, adjusting product mix and increasing international certications.

 2) Analysis of production and sales
    √ Applicable □ N/A


                                                                        Inventory YoY change in YoY change        YoY change in
     Main products            Unit            Production        Sales
                                                                            level production (%) in sales (%)      inventory (%)
     Ilaprazole sodium for    ten thousand
                                                1,436.29    1,245.05      316.14            94.86         97.94           152.43
     injection                boxes
     Leuprorelin Acetate
                              Ten thousand
     Microspheres for                             155.70      137.53            -           48.23         31.42                 -
                              ampules
     Injection
     Ilaprazole Enteric-      ten thousand
                                                1,950.88    2,055.40      239.36            26.87         46.94           -30.39
     Coated Tablets           boxes
     Meropenem for            Ten thousand
                                                1,826.21    1,977.24      150.75            14.66         11.57           -51.38
     Injection                ampules
     7-ACA (including
                              ton               2,903.89    2,986.98       55.88            45.00         44.49           -64.48
     D-7ACA)


     Explanations on production and sales

     During the Reporting Period, the COVID-19 pandemic was basically and effectively controlled in China, and medical order
     was gradually restored to normal. The Company actively implemented sales deployment, strengthened market promotion,
     reinforced sales specialization and delicacy management. Therefore, during the Reporting Period, sales revenue of main
     varieties in key specialist areas of the Company kept steady growth, and the production and sales volume grew in proportion.
     The changes in inventory was mainly due to the stock-up in the beginning of the year and the demand-supply position change
     during the year end.

 3) Performance of major procurement contracts and major sales contracts
    □ Applicable √ N/A




28
                                                                                                         Annual Report
                                                                                                                 2021


4) Cost analysis
                                                                                                                    Unit: Yuan
                                                Cost Components by Industry
                                                                     As a                      As Percentage in
                                                                          Amount incurred in                           YoY
                                         Amount incurred in percentage                         total costs in the
    Industry       Cost components                                         the same period of                        Change
                                          the current period of operating                        same period of
                                                                                previous year                           (%)
                                                                 costs(%)                     previous year (%)
                   Costs of materials      3,426,827,118.77         59.95     3,089,084,780.11             63.38       10.93
                   Labor costs              619,622,563.47          10.84      448,186,516.57               9.20       38.25
    Industrial
                   Manufacturing costs     1,487,278,456.52         26.02     1,137,339,779.71             23.33       30.77
    and
                   Depreciation              322,761,251.80          5.65      276,175,262.41                5.67      16.87
    commercial
                   Others                   -141,969,567.28         -2.48      -79,351,536.71               -1.63      78.91
                   Total                   5,714,519,823.28         99.97     4,871,434,802.09             99.94       17.31
                   Costs of materials            408,782.66          0.01          898,200.38               0.02      -54.49
                   Labor costs                 1,022,280.28          0.02        1,315,269.00               0.03      -22.28
    Service
                   Manufacturing costs           223,280.63          0.00          415,334.88               0.01      -46.24
    industry
                   Depreciation                  119,720.73          0.00          123,291.70               0.00       -2.90
                   Total                       1,774,064.30          0.03         2,752,095.96              0.06      -35.54
                   Costs of materials      3,427,235,901.43         59.96     3,089,982,980.49             63.39       10.91
                   Labor costs              620,644,843.75          10.86      449,501,785.57               9.22       38.07
                   Manufacturing costs     1,487,501,737.14         26.02     1,137,755,114.59             23.34       30.74
    Total
                   Depreciation              322,880,972.53          5.65      276,298,554.11                5.67      16.86
                   Others                   -141,969,567.28         -2.48      -79,351,536.71               -1.63      78.91
                   Total                   5,716,293,887.58      100.00     4,874,186,898.05              100.00       17.28
                                                 Cost Components by Product
                                                                     As a                      As Percentage in
                                                                          Amount incurred in                           YoY
                                         Amount incurred in percentage                         total costs in the
    Product        Cost components                                         the same period of                        Change
                                          the current period of operating                        same period of
                                                                                previous year                           (%)
                                                                 costs(%)                     previous year (%)
                   Costs of materials         26,560,959.72          0.46       33,355,073.53               0.68      -20.37
                   Labor costs                 6,336,694.50          0.11        7,403,326.99               0.15      -14.41
    Healthcare     Manufacturing costs         2,677,541.36          0.05         6,875,531.21              0.14      -61.06
    products       Depreciation                2,564,510.61          0.04         1,195,160.19               0.02     114.57
                   Others                     -4,487,206.18         -0.08        -3,146,679.93              -0.06      42.60
                   Total                      33,652,500.02          0.59       45,682,412.00               0.94      -26.33
                   Costs of materials      3,359,165,272.77         58.76     3,003,987,376.89             61.63       11.82
                   Labor costs              611,624,924.03          10.70      440,395,045.89               9.04       38.88
    Medicine       Manufacturing costs     1,435,952,937.90         25.12     1,105,950,570.61             22.69       29.84
    Products       Depreciation              320,084,243.85          5.60      268,333,896.16                5.51      19.29
                   Others                   -157,879,982.96         -2.76      -76,427,205.33               -1.57     106.58
                   Total                   5,568,947,395.59         97.42     4,742,239,684.22             97.29       17.43




                                                                                                                           29
     Other information on cost analysis

     Cost and variety of main medicinal herbs used in main TCMs


                   Variety of main                                            Procurement
     Main TCMs                                 Supply and demand                                Inuence of price uctuation
                   medicinal herbs                                            model
                                   The supply is relatively stable. Both
                                   medicinal herbs are supplied by
                                   plantation bases and external suppliers.
                                   Plantation Base of Livzon Group
                                   Limin Pharmaceutical Manufacturing
                                   Factory (“Livzon Limin Base”)            Supplied       1. Codonopsis Root's purchase price
     Shenqi        Codonopsis      maintains safety stock of medicinal        by Livzon      fall compared with the same period
     Fuzheng       Root and        herbs, which ensures the supply            Limin Base     last year; 2. Astragalus Root: stay
     Injection     Astragalus Root quantity and stabilizes the supply         and external   the same compared with the same
                                   price. Meanwhile, Limin signed annual      suppliers      period last year.
                                   demand-based supply agreements with
                                   external suppliers who are obligated to
                                   stock up according to Limin's quality
                                   requirements, so as to ensure sucient
                                   supply of herbs with stable quality.
                                                                                          Price of main raw medicinal herbs
                                                                                          used in Anti-Viral Granules stays
                                                                                          the same compared with the same
                                                                                          period last year. Specically, price
                   Indigowoad
                                                                                          of Fructus Forsythiae increases
                   Root, Fructus
                                                                                          signicantly due to reduced
                   Forsythiae,
                                                                                          production in main producing areas
                   Anemarrhena,
     Anti-Viral                                                                           caused by spring frost and extreme
                   Acori graminei
     Granules,                                                                            weather; price of Rehmanniae
                   Rhizoma,
     Anti-Viral                                                                           Radix increases signicantly due to
                   Gypsum,           There is sucient supply of main raw
     Granules                                                                 Tendering   reduced production in Henan and
                   Rhizoma           medicinal herbs used in Anti-Viral
     (Sugar-free),                                                            procurement Shanxi caused by extreme rainstorm
                   Phragmitis,       Granules
     Anti-Viral                                                                           and ood; price of Patchouli
                   Patchouli,
     Syrup, Anti-                                                                         falls largely thanks to eective
                   Rehmanniae
     Viral Tablets                                                                        prevention and control of the
                   Radix, Radix
                                                                                          epidemic; price of Indigowoad Root,
                   Curcumae,
                                                                                          Anemarrhena, and Acori graminei
                   Dahurian
                                                                                          Rhizoma records a small increase
                   Angelica Root
                                                                                          as aected by market demand and
                                                                                          supply; purchase price of Rhizoma
                                                                                          Phragmitis, Gypsum and Radix
                                                                                          Curcumae stays relatively the same.


 5) Changes in consolidation scope due to equity change of major subsidiaries during the Reporting Period
    □ Applicable √ N/A

 6) Material changes or adjustments in business, products or services during the Reporting Period
    □ Applicable √ N/A




30
                                                                                                             Annual Report
                                                                                                                     2021


7) Major customers of sales and major suppliers

   A. Major customers of sales

   Sales to top 5 customers were RMB 1,372.03 million, representing 8.63% of the total annual sales; none of which is the sales
   to related parties.

    Sales to any individual customer in excess of 50% of the total, any new customer in top 5 customers or heavy dependence on a
    few customers during the Reporting Period
    □ Applicable √ N/A

   B. Information on major suppliers

   Purchases from top 5 suppliers were RMB 839.93 million, representing 20.54% of the total annual purchase cost, of which the
   purchases from related parties wereRMB 212.59 million, representing 5.20% of the total purchase cost.

   Purchases from any individual supplier in excess of 50% of the total, any new supplier in top 5 suppliers or heavy dependence
   on a few suppliers during the Reporting Period
   □ Applicable √ N/A

3. Expenses
   √ Applicable □ N/A
                                                                                                                       Unit:Yuan
    Item                               2021                2020    YoY Change                     Explanations

    Selling expenses      5,026,812,145.41     3,940,337,105.29         27.57%      No material changes

    Administrative
                            939,253,444.33        950,827,562.47         -1.22%     No material changes
    expenses

    Financial expenses      -92,894,751.72        -98,885,820.58            N/A     No material changes

                                                                                    Mainly due to an increase in the number of
    R&D expenses          1,397,131,273.33     1,071,711,981.95         30.36%      R&D projects, as well as an expansion of
                                                                                    R&D scale and investment.


4. Investment in R&D
1) Investment in R&D
   √ Applicable □ N/A
                                                                                                                      Unit: Yuan
    Current expensed R&D expenditure                                                                          1,397,131,273.33
    Current capitalized R&D expenditure                                                                          452,684,306.26
    Total R&D expenditure                                                                                     1,849,815,579.59
    Total amount R&D expenditure as a percentage of Revenues (%)                                                          11.63
    Ratio of capitalized R&D expenditure (%)                                                                              24.47




                                                                                                                              31
 2) R&D Sta
    √ Applicable □ N/A


     Number of R&D personnel                                                                                               1,615
     Proportion of R&D personnel to the total employees (%)                                                                12.20
                                                 Education background of R&D sta
     Degree level                                                                                                        Number
     PhD                                                                                                                      55
     Master                                                                                                                  409
     Bachelor                                                                                                                749
     Junior college graduate                                                                                                 293
     Graduate from high school and lower                                                                                     109
                                                    Age composition of R&D sta
     Age composition of R&D sta                                                                                          Number
     Under 30 years old (exclusive)                                                                                          788
     30-40 years old (including 30 years old, excluding 40 years old)                                                        612
     40-50 years old (including 40 years old, excluding 50 years old)                                                        165
     50-60 years old (including 50 years old, excluding 60 years old)                                                         50
     Over 60 years old                                                                                                             0


 3) Explanations
    √ Applicable □ N/A

     During the Reporting Period, total investment of the Company amounted to RMB 1,849.82 million, representing a year-on-
     year growth of 46.75%, accounting for 11.63% of total Revenues and 9.17% of total net assets. During the Reporting Period,
     the Company's investment in R&D was mainly used for R&D of new products and upgrading and reconstruction of project
     technology. As biologics, inhalation preparations and other projects entered the clinical stage, R&D expenditures increased
     signicantly.

 4) Reasons for and impact of the material change in the composition of R&D staff personnel on future development of the
    Company
    □ Applicable √ N/A

 5. Cash ows
    √ Applicable □ N/A


     Item                                2021                2020   YoY Change                    Explanations
     Net cash ow from
                            2,563,089,045.24    3,024,999,592.24        -15.27% No material changes
     operating activities
                                                                               Mainly due to the payment of consideration
                                                                               for the acquisition of equity interest in Tianjin
     Net cash ow from                                                          Tongrentang Group Co., Ltd. ( 天津同仁
                            -1,964,157,731.17    -500,320,691.78           N/A
     investing activities                                                      堂集团股份有限公司 ) and the increase in
                                                                               investment for construction of new plants and
                                                                               workshops of some subsidiaries.
     Net cash ow from
                               -974,904,353.44 -1,238,212,948.15           N/A No material changes
     nancing activities




32
                                                                                                                                                 Annual Report
                                                                                                                                                         2021


(II) Statement on material changes in profits arising from non-principal businesses
    √ Applicable □ N/A
                                                                                                                                                              Unit: Yuan
                                                              As a percentage
     Item                                       Amount                                                Reason for occurrence                              Sustainability
                                                                of total prot
                                                                                 Mainly due to changes in prot and loss from
                                                                                 investments in associates and gains generated
     Investment income                 71,881,264.65                       2.43%                                                                              No
                                                                                 upon expiration of forward foreign exchange
                                                                                 settlement contracts.
     Gains or losses arising
                                                                                      Mainly due to uctuations in the market value
     from changes in fair             -23,506,126.09                      -0.80%                                                                              No
                                                                                      of subject securities investment held.
     value
                                                                                      Mainly due to impairment provisions for
     Asset impairment cost            -62,950,978.72                      -2.13%                                                                              No
                                                                                      inventories.
     Non-operating
                                         8,641,830.86                      0.29% Mainly due to income on disposal of obsolete.                                No
     Revenues
     Non-operating                                                                    Mainly due to donation payments and loss on
                                       39,379,273.69                      -1.33%                                                                              No
     expenditure                                                                      scrapping of xed assets.
                                                                                      Mainly due to the government subsidies
     Other income                    247,346,934.96                        8.38%                                                                              Yes
                                                                                      received.


(III) Analysis of assets and liabilities
    √ Applicable □ N/A

1. Status of assets and liabilities
                                                                                                                                                              Unit: Yuan
                                                    Proportion of                          The proportion of     Change
                           Ending balance of    closing balance of    Ending balance of   closing balance of         in
     Item                                                                                                                                  Explanations
                                  this period    this period to the     previous period   previous period to     amount
                                                  total assets (%)                        the total assets (%)      (%)
                                                                                                                          Mainly due to the subsidiary Livzon Group
     Financial assets                                                                                                     cancelled the investment in SCC VENTURE
                             184,638,344.31                   0.59       28,328,748.72                   0.10    551.77
     held for trading                                                                                                     VII 2018-C, L.P., and received the distributed
                                                                                                                          shares.
                                                                                                                          Mainly due to the increase of sales revenues
     Bills Receivables     1,977,286,022.02                   6.36    1,343,013,818.54                   4.77     47.23
                                                                                                                          during the reporting period.
                                                                                                                          Mainly due to an increase of payment of raw
     Prepayments             369,232,546.29                   1.19      209,926,040.57                   0.75     75.89
                                                                                                                          material purchase.
                                                                                                                          Mainly due to the receipt of Yunfeng's
     Other receivables        88,053,825.12                   0.28      177,240,162.81                   0.63    -50.32
                                                                                                                          payment during the reporting period.
     Non-current assets                                                                                                   Mainly due to the subsidiary Livzon Group
     due within one              317,381.23                   0.00       19,934,376.07                   0.07    -98.41 collected the equity transfer price of an
     year                                                                                                                 invested company.
     Other current                                                                                                        Mainly due to an increase of excess VAT
                              83,986,214.37                   0.27       58,098,049.20                   0.21     44.56
     assets                                                                                                               credits and prepaid corporate income tax.
     Long-term equity                                                                                                     Mainly due to Livzon Group acquired 40%
                           1,419,349,454.84                   4.56      628,279,599.73                   2.23    125.91
     investments                                                                                                          share of Tianjin Tongrentang Group Co. LTD.
                                                                                                                          Mainly due to an increase of leases longer
     right-of-use assets      46,774,759.69                   0.15       18,030,132.69                   0.06    159.43
                                                                                                                          than one year.




                                                                                                                                                                         33
                                                      Proportion of                          The proportion of     Change
                             Ending balance of    closing balance of    Ending balance of   closing balance of         in
      Item                                                                                                                                    Explanations
                                    this period    this period to the     previous period   previous period to     amount
                                                    total assets (%)                        the total assets (%)      (%)
                                                                                                                            Mainly due to an increase in R&D
      Development                                                                                                           expenses Investment in the overseas phase
                               786,993,435.71                   2.53      399,119,603.78                   1.42     97.18
      expenditure                                                                                                           III clinical trials of a project researched and
                                                                                                                            developed by Livzon MAB
      Other non-current                                                                                                     Mainly due to the increase in
                               663,584,003.80                   2.13      373,557,910.72                   1.33     77.64
      assets                                                                                                                prepayment for project and equipment.
                                                                                                                            Mainly due to an increase of bank acceptance
      Bills payable          1,582,386,767.93                   5.09    1,087,759,353.31                   3.86     45.47
                                                                                                                            bills paid.
                                                                                                                            Mainly due to an increase of the collection of
      Contract liabilities     234,140,702.29                   0.75      133,422,354.03                   0.47     75.49
                                                                                                                            contract advances by the Company.
      Non-current                                                                                                           Mainly due to the reclassication of long-
      liabilities due           91,576,066.33                   0.29        8,539,077.05                   0.03    972.44 term loans due within one year as non-current
      within one year                                                                                                     liabilities due within one year.
      Other current                                                                                                         Mainly due to an increase of output VAT
                                15,626,224.29                   0.05        6,267,034.79                   0.02    149.34
      liabilities                                                                                                           debits.
                                                                                                                            Mainly due to an increase of bank long-term
      Long-term loans          826,780,252.78                   2.66      360,324,027.48                   1.28    129.45
                                                                                                                            loans.
      Leasing liabilities       25,071,794.32                   0.08        9,817,780.04                   0.03    155.37 Mainly due to the increase in leases payable.
      Other                                                                                                                 Mainly due to the disposal of investment in
      comprehensive              5,387,545.97                   0.02      116,300,559.28                   0.41    -95.37 other equity instruments, transferring other
      income                                                                                                                comprehensive income to retained earnings.


 2. Overseas assets
    √ Applicable □ N/A

 (1) Asset size
     Of which: Overseas assets were 37.34 (Unit: 100million Currency: RMB), representing 12.03% of the total assets.

 (2) Statement on high proportion of overseas assets
     □ Applicable √ N/A

 3. Restrictions on assets entitlements as at the end of the Reporting Period
    √ Applicable □ N/A
                                                                                                                                                                Uint: Yuan
                                                   Book value
      Item                                                                                       Reasons for being subject to restriction
                                              (Ending Balance)
      Other monetary funds                         11,742,597.03            Letter of credit, bank acceptance bill and forward settlement deposit, etc.
      Bills receivable                            870,153,979.75            Bills Pooling Business, bills receivables pledged
      Total                                       881,896,576.78


 4. Others
    □ Applicable √ N/A




34
                                                                                                               Annual Report
                                                                                                                       2021


(IV) Analysis of industry-related business information
    √ Applicable □ N/A

    According to the Guidelines for the Industry Classification of Listed Companies (2012 Revision) issued by CSRC, the
    Company was operating in the pharmaceutical manufacturing industry. Adhering to the mission of“ For the health, For the
    future”and the vision of“Attentively developing high-quality medicines and innovative medicines”, the Company has been
    committed to the pharmaceutical business and been strengthening R&D, production, marketing and management of medical
    products, to strive to become a domestic leading comprehensive pharmaceutical enterprise with capacity for independent
    innovation and international competitiveness in terms of production, technology and management in the near future.

    Analysis of business information on pharmaceutical manufacturing industry

1. Basic information on industry and main drugs (products)

(1). Basic information on industry
     √ Applicable □ N/A

I) Inuence of industry policies

    In 2021, multiple pharmaceutical industry policies were launched. The 14th Five-Year Plan for A Healthcare Security System
    with Universal Coverage was released. The practice of centralized volume-based procurement and use of drugs was further
    expanded. The catalog of medicines covered by medical insurance system was modied. DRG payment reform was initiated.
    All those movements exerted far-reaching impact on the industry. Some of the main policies that have a signicant impact on
    the Company are as follows:

1) 14th Five-Year Plan for A Healthcare Security System with Universal Coverage was released.

    On September 23, 2021, Executive Meetings of the State Council reviewed, approved, and released the nation's first special
    plan for the development of healthcare security system - 14th Five-Year Plan for A Healthcare Security System with Universal
    Coverage. The plan, under the guidance of Xi Jinping Thought on Socialism with Chinese Characteristics, aims to promote
    the implementation of Healthy China strategy. The plan clearly proposes to establish a fair, law-based, safe, intelligent, and
    collaborative healthcare security system, and anticipates a more mature and stable healthcare security system, standardization
    of healthcare security policies, rened management, convenient services, and more collaborative reform by 2025. By 2035, the
    basic healthcare security system will be more standardized and unied, the multi-level healthcare security system will be more
    rened, and the superiority of the healthcare security system with Chinese characteristics will be fully revealed.

2) Volume-based procurement becomes normalized.

    On January 28, 2021, the State Council published the Opinions on Promoting the Normalization and Institutionalization
    of Centralized Volume-Based Procurement of Drugs to improve the market-driven drug price mechanism and promote the
    normalization and institutionalization of centralized volume-based procurement of drugs.

    On January 15, 2021, the state's Joint Drug Procurement Office issued an announcement on National Centralized Drug
    Procurement (GY-YD2021-1); on February 8, 2021, the state's Joint Drug Procurement Office announced the Selected Drugs
    in the Fourth-Round National Centralized Drug Procurement (GY-YD2021-1) and the List of Varieties of Selected Drugs to Be
    Supplied (GY-YD2021-1).

    On June 2, 2021, the state's Joint Drug Procurement Office issued an announcement on National Centralized Drug
    Procurement (GY-YD2021-2); on June 28, 2021, the state's Joint Drug Procurement Office announced the Selected Drugs in
    the Fifth-Round National Centralized Drug Procurement (GY-YD2021-2) and the List of Varieties of Selected Drugs to Be
    Supplied (GY-YD2021-2).

    On November 15, 2021, the state's Joint Drug Procurement Office issued an announcement on National Centralized Drug
    Procurement (Insulin) (GY-YD2021-3); on November 30, 2021, the state's Joint Drug Procurement Office announced the
    Selected Drugs in the Sixth-Round National Centralized Drug Procurement (Insulin) and the List of Varieties of Selected
    Drugs to Be Supplied.



                                                                                                                               35
 3) The catalog of medicines covered by medical insurance is modied.

     On May 10, 2021, the National Healthcare Security Administration and the National Health Commission jointly issued
     the Guiding Opinions on Establishing and Improving the“Dual Channel”Management Mechanism for Drugs in National
     Medical Insurance Negotiations. On June 30, 2021, the National Healthcare Security Administration issued the 2021 Work
     Plan for Modifying the Catalog of Drugs Covered by National Medical Insurance System, and simultaneously issued the 2021
     Guidelines on Application for Modifying the Catalog of Drugs Covered by National Medical Insurance System. On September
     10, 2021, the National Healthcare Security Administration and the National Health Commission officially issued the Notice
     on Adapting to the N ormalization of National Medical Insurance Negotiations and Continuing to Ensure the Adoption of
     Negotiated Drugs.

     In November 2021, according to 2021 Work Plan for Modifying the Catalog of Drugs Covered by National Medical Insurance
     System, the National Healthcare Security Administration and the Ministry of Human Resources and Social Security jointly
     organized negotiation on inclusion of drugs into the Catalog of Drugs Covered by National Medical Insurance System. As
     a result, the Catalog of Drugs Covered by National Basic Medical Insurance, Work-Related Injury Insurance and Maternity
     Insurance (2021) was published on December 3, 2021 and would come into effect from January 1, 2022. Through the
     negotiation, a total of 94 drugs were successfully negotiated and the payment standards were established.

 4) Reform of DRG/DIP payment method implemented industy-wide.

     To promote reform of medical insurance related payment method and further deepen the DRG/DIP payment reform, the
     National Healthcare Security Administration issued the Rules for Diagnosis-Intervention Packet (DIP) Payment Agency
     Services (Pilot) on July 15, 2021. On November 26, 2021, the National Healthcare Security Administration issued the Notice
     of the National Healthcare Security Administration on the Issuance of the Three-Year Action Plan for the Reform of DRG/
     DIP Payment Methods. According to the Notice, all areas reimbursed by the pooled fund will carry out reform of DRG/DIP
     payment by the end of 2024.

     On December 17, 2021, the National Healthcare Security Administration issued the Notice on the Issuance of the List of
     Demonstration Sites of DRG/DIP Payment. Prepared after evaluation on voluntary applicants, the list includes 18 DRG
     demonstration sites, 12 DIP demonstration sites and 2 DRG/DIP demonstration sites.

 5) The reform of medical service price will be deepened.

     On August 31, 2021, eight ministries including the National Healthcare Security Administration, the National Health
     Commission and National Development and Reform Commission issued the Pilot Program for Deepening the Reform of
     Medical Service Price. This program expects to gather replicable and extendable experience in the reform of medical service
     price through 3-5 years' pilot practice. By 2025, the experience will be extended to the whole country. The medical service
     price mechanism featured classied management, hospital participation, scientic determination and dynamic adjustment will
     be mature and nalized with the price leverage role coming into full play.

 6) API industry is undergoing high-quality development

     On November 9, 2021, the National Development and Reform Commission and the Ministry of Industry and Information
     Technology jointly issued the Implementation Plan to Promote the High-quality Development of the API Industry. The plan
     emphasizes that chemical APIs are the basic raw materials and active ingredients of drugs, and are an important part of the
     pharmaceutical industry. By 2025, the nation will develop a batch of high value-added and high-growth varieties, make a
     breakthrough in a batch of green and low-carbon technology and equipment, cultivate a batch of internationally competitive
     leading enterprises, and establish a batch of industrial clusters and production bases with global inuence.




36
                                                                                                               Annual Report
                                                                                                                       2021


7) Faster progress is made in inheritance and innovation of TCMs

   On December 28, 2021, the Office of the National Healthcare Security Administration and the Office of the National
   Administration of Traditional Chinese Medicine issued the Notice on Updating the Classification and Codes of Diseases and
   Patterns of Traditional Chinese Medicine (Covered by Medical Insurance). As indicated by the notice, the classification and
   codes of diseases and patterns of traditional Chinese medicine in the Classification and Code of Diagnosis and Operation of
   Diseases Covered by Medical Insurance (GB/T15657-2021) shall be updated and take eect from January 1, 2022.

   On 31 December 2021, the National Healthcare Security Administration and the Office of the National Administration of
   Traditional Chinese Medicine jointly issued the Guiding Opinions on Supporting the Inheritance, Innovation and Development
   of Traditional Chinese Medicine with Healthcare Security System. The Opinions propose to recognize qualied TCM medical
   institutions as medical insurance designated sites, and allow TCMs and medical services to be paid by medical insurance fund.
   Also, the Opinions stress the need to improve the payment policy suitable for TCMs and strengthen the price management.

   Response measures: The Company will take effective measures to cope with major changes in policies of the pharmaceutical
   industry through early layout, transformation and compliance, and constantly improve its core competitive strength. To build
   strengths and core competitiveness, the Company will: emphasize more on R&D and innovation of new products to drive
   development; adhere to high standards of consistency evaluation; do its best endeavor to apply for medical insurance coverage;
   maintain the competitive sales of large varieties while keeping striving for market access and promoting sales to lower-tier
   markets; create more competitive advantages of products; improve the production quality management; standardize the safe
   and environmentally friendly production; operate in compliance with regulations, and establish a more reasonable market-
   oriented system.

II) Basic information on the segment where the Company belongs

   The Company is primarily engaged in the R&D, production and sale of hundreds of varieties of pharmaceutical products in
   areas such as chemical drug preparation products, chemical active pharmaceutical ingredients (APIs), traditional Chinese drug
   preparation products, and intermediates, diagnostic reagents and equipment, and healthcare products. Basic information on the
   market niches in which the Company operates are follows:

   Chemical drug preparation products: In recent years, influenced by policies regarding medical insurance payment control,
   volume-based procurement and consistency evaluation, chemical drug preparation products have recorded a slower growth
   in revenue and profit. The market of chemical drug preparation products is relatively competitive as there are many domestic
   manufacturers. However, innovative drugs and high-barrier preparations will become an industry trend and an important source
   of profits thanks to low competitive pressure and continuous support from national policies. The Company's chemical drug
   preparation products cover many therapeutic fields with competitive strengths in product varieties, sales channels, end user
   groups and brand awareness. In the future, the Company will speed up research and development, introduce new technologies,
   accelerate the product structure adjustment and strategic layout to cope with the increasingly erce market competition.

   Chemical APIs: At present, the Company has the following chemical APIs: cephalosporin series, statin series, and
   carbapenem series among others. Restricted by heavy investment, long construction period, high technical threshold and
   strict environmental protection requirements, the bulk API market in China is relatively concentrated. However, overcapacity
   causes erce competition. To adapt to future competition, the Company gradually completed the transformation and upgrading
   from bulk APIs to high-end characteristic APIs, from nonstandard market to standardized market and from domestic market
   to international market. Meanwhile, in an effort to further implement the Implementation Plan to Promote the High-quality
   Development of the API Industry issued by the National Development and Reform Commission and the Ministry of Industry
   and Information Technology in November 2021, the Company strengthened forward-looking research layout to accelerate
   high-quality development of APIs under new background. Since October 2020, the Company has focused on building a
   research and development platform in synthetic biology with AI integrated to promote green, low-carbon transformation of the
   industry, give more added value to pharmaceutical intermediates and APIs, and accelerate integration into the global industrial
   chain and value chain.




                                                                                                                               37
     Traditional Chinese medicine (TCM): In recent years, encouraged by many favorable national policies, the TCM industry
     has gained abundant opportunities to grow. Since 2021, the state has successively issued several policies, including the
     Several Policies and Measures on Accelerating the Characteristic Development of Traditional Chinese Medicine, the Notice
     on Updating the Classification and Codes of Diseases and Patterns of Traditional Chinese Medicine (Covered by Medical
     Insurance) and the Guiding Opinions on Supporting the Inheritance, Innovation and Development of Traditional Chinese
     Medicine with Healthcare Security System. These policies emphasize the need to optimize the TCM evaluation and approval
     management, improve the classification and registration management, implement suitable payment policies, strengthen
     the price management, adopt integrative medicine approach, and promote the development of TCM industry. In the fight
     against the epidemic, three drugs and three prescriptions of TCM play an important role in clinic treatment, highlighting
     the importance of TCM. Shenqi Fuzheng Injection, Anti-Viral Granules and other products from Livzon Group, a holding
     subsidiary of the Company, are representatives of the Company's TCM products. In the future, the Company will continue to
     intensify R&D and technological innovation to drive sustainable protability.

     Diagnostic reagents and equipment: As China's healthcare industry develops gradually, in vitro diagnostic reagents industry
     is seeing a bigger market but remains in primary stage compared with developed countries such as European countries and
     America. With more product varieties and more advanced technologies, in vitro diagnostic reagents are used in more scenarios,
     from traditional hospital laboratories to third-party medical diagnostic institutions, physical examination centers, families
     and other primary healthcare institutions. More application scenarios fully release the demand for different kinds of in vitro
     diagnostic reagents, promoting rapid development of the industry. Since its establishment, Livzon Diagnostics, controlled by
     Livzon Group (a holding subsidiary of the Company), has been committed to the R&D, production and sales of diagnostic
     reagents and equipment. After years of efforts and development, it has built a multi-faceted technical platform that supports
     ELISA test, colloidal gold rapid test, chemiluminescence assay, multiplex liquid-chip assay, and nucleic acid assay. It has
     strong market inuence in such elds as respiratory infection, infectious diseases, and drug concentration monitoring. Some of
     its products hold big market shares in China.

     Health care products: Driven by increasing public awareness of wellness, aging, consumption upgrading and promotion of
     direct sales, health care industry has developed rapidly in recent years. However, due to low technical threshold and high gross
     prot, the domestic market is witnessing erce competition, product homogeneity and low concentration. Well-known brands
     such as“Taitai” 太 太 ),“Jingxin” 静 心 ) and“Eagle's” 鹰 牌 ) have gained wide recognition. In the face of erce market
     competition, while staying committed to traditional pharmaceutical chain channels, the Company also vigorously expands
     online channels through strategic cooperation with new social e-commerce sales platforms to drive sales growth. In addition,
     the Company actively prepares to access to fields of special medical purpose and functional food by leveraging its R&D and
     market strengths to add product pipelines and enhance core competitiveness.




38
                                                                                                                                                        Annual Report
                                                                                                                                                                2021


(2). Basic information on main drugs (products)
     √ Applicable □ N/A

    Basic information on main drugs (products) by segment and therapeutic areas
    √ Applicable □ N/A

                                                                                                                                           New drug      Included    Covered
                                                                                                         Protected
                                                                                                                       Eective and         (product)      in the        by
                                                                                                         traditional
                                                                                                                       expiration date     launched     Catalog of   national
                     Main treatment   Name of drug    Registration                        Prescription    Chinese
     Segment                                                         Indications                                       of patent right     during the    National    medical
                     eld              (product)       classication                        drug or not    medicine
                                                                                                                       for invention (if   Reporting     Essential   insurance
                                                                                                          or not (if
                                                                                                                       applicable)         Period or     Drugs or    system or
                                                                                                         applicable)
                                                                                                                                              not          not          not
     Chemical drug                    Ilaprazole      Chemical                                                         From 23 October
                                                                     Peptic ulcer
     preparation     Gastroenterology Sodium for      drugs                                   Yes            No        2009 to 23             No           No          Yes
                                                                     bleeding
     products                         Injection       Class 2                                                          October 2029
                                      Leuprorelin                    Endometriosis,                                    From 23
     Chemical drug                                    Chemical
                     Gonadotropic     Acetate                        hysteromyoma,                                     December 2010
     preparation                                      drugs                                   Yes            No                               No           No          Yes
                     hormones         Microspheres                   breast cancer,                                    to 23 December
     products                                         Class 6
                                      for Injection                  etc.                                              2030
     Chemical drug                    Ilaprazole      Chemical       Duodenal ulcer                                    From 24 March
     preparation     Gastroenterology Enteric-Coated drugs           and reux                 Yes            No        2006 to 24             No           No          Yes
     products                         Tablets         Class 1.1      esophagitis                                       March 2026
                                                                     Used to treat                                     From 6 June
                                                                     infection caused                                  2006 to 6 June
     Chemical drug                                    Chemical
                                      Meropenem for                  by one bacterium                                  2026
     preparation     Anti-infection                   drugs                                   Yes            No                               No           No          Yes
                                      Injection                      or more bacteria                                  From 31 July
     products                                         Class 4
                                                                     sensitive to                                      2012 to 31 July
                                                                     meropenem.                                        2032
    Note: The starting and expiration dates listed above refer to the corresponding term of patents of core products in each product
    category.

    Main drugs (products) newly added into and exited from the Catalog of National Essential Drugs and the catalog of medicines
    covered by medical insurance system during the Reporting Period
    √ Applicable □ N/A


                                                                                Catalog of National                       Catalog of Medicines Covered by
     Name of main products
                                                                                 Essential Drugs                         National Medical Insurance System
     Ilaprazole Sodium for Injection                                                  Not included                                          Included
     Leuprorelin Acetate Microspheres for Injection                                   Not included                                          Included
     Ilaprazole Enteric-Coated Tablets                                                Not included                                          Included
     Meropenem for Injection                                                          Not included                                          Included




                                                                                                                                                                              39
     Winning bids for main drugs in centralized drug procurement during the Reporting Period
     √ Applicable □ N/A


                                                                                  Total actual procurement
     Name                                              Winning bid price range          volume by medical             Unit
                                                                                                institutions
     Ilaprazole Sodium for Injection                            RMB 156                           1,299.37 Ten thousand ampules
     Leuprorelin Acetate Microspheres for Injection RMB 1,295.90~1,409.36                           148.89 Ten thousand boxes
     Ilaprazole Enteric-Coated Tablets (6 tablets)         RMB 78.34~102.09                       1,535.36 Ten thousand boxes
     Ilaprazole Enteric-Coated Tablets (10 tablets)       RMB 156.30~161.12                         109.46 Ten thousand boxes
     Meropenem for Injection 0.25g                           RMB 54.05~63.3                         618.54 Ten thousand ampules
     Meropenem for Injection 0.5g                          RMB 86.30~108.08                       1,186.70 Ten thousand ampules
     Meropenem for Injection 1g                           RMB 157.20~187.70                           68.41 Ten thousand ampules


     Explanations
     √ Applicable □ N/A

     (1) Data regarding Total actual procurement volume by medical institutions are from IQVIA;
     (2) The information disclosed is the winning price of the tenderee province and newly implemented winning prices during the
         Reporting Period.

     Operating data by therapeutic areas or main drug (products)
     √ Applicable □ N/A
                                                                                                     Unit: 10,000 Yuan Currency: RMB
                                                                                                                 Gross prot margin
                                                                   YoY change     YoY change     YoY change
                            Operating   Operating Gross prot                                                      of products in the
     Therapeutic area                                              in operating   in operating in gross prot
                              income        costs margin (%)                                                       same eld in the
                                                                   income (%)        costs (%)    margin (%)
                                                                                                                      same industry
     Gastroenterology    371,790.91     45,364.70        87.80           50.40          42.78             0.65               85.39%
     Gonadotropic
                         245,355.67     86,255.72        64.84           28.34          24.21             1.17                     -
     hormones
     Anti-infection      156,128.38     25,332.56        83.77            7.84          20.47            -1.70               53.54%
     Respiratory            57,709.55   10,663.88        81.52          657.53         592.10             1.75               84.95%


     Explanations
     √ Applicable □ N/A

     ① The gross prot margin of products in the eld of gastroenterology is derived from that of the relevant industry in“Major
        products of metabolism and alimentary system”in Fosun Pharma's 2020 Annual Report.
     ② No comparable data on gross prot margin in the eld of gonadotropic hormones has been found.
     ③ The data on the gross prot margin of products in the eld of anti-infection comes from that of“anti-infection category”in
        the 2020 Annual Report of Tianyao Co., Ltd.
     ④ The gross prot margin data of products in the eld of the respiratory comes from that of“respiratory system category”in
        Luoxin Pharmaceutical's 2021 Annual Report.




40
                                                                                                                   Annual Report
                                                                                                                           2021


2. Drug (product) R&D of the Company

(1). Overview of R&D of the Company
     √ Applicable □ N/A

(1) Chemical drug preparation products

    1. High-barrier complex preparations: There were a total of 40 projects under research, of which, four had been applied for
    production and 7 had started clinical/BE study. The progress of the major projects was as follows

    Inhalation preparations: Tobramycin Solution for Inhalation ( 妥 布 霉 素 吸 入 溶 液 ), Formoterol Fumarate Solution for
    Inhalation ( 富马酸福莫特罗吸入溶液 ) and Terbutaline Sulphate Solution for Nebulization ( 硫酸特布他林雾化吸入溶液 )
    had been applied for production; Formoterol Fumarate Inhalation Aerosol ( 富 马 酸 福 莫 特 罗 吸 入 气 雾 剂 ) and Mometasone
    Furoate and Formoterol Fumarate Dihydrate Inhalation Aerosol ( 莫米松福莫特罗吸入气雾剂 ) had started clinical study, and
    Aclidinium Bromide Powder for Inhalation ( 阿地溴铵吸入粉雾剂 ) had received the notice of clinical trials;

    Sustained-release microspheres: Triptorelin Acetate Microspheres for Injection ( 注 射 用 醋 酸 曲 普 瑞 林 微 球 ) (one-month
    sustained release) had been applied for production registration after completing the phase III clinical trials, and received the
    notication of acceptance of the production application. Aripiprazole Microspheres for Injection ( 注射用阿立哌唑微球 ) were
    currently undergoing phase I clinical trials. The single dose study had been completed, and multiple dose clinical trials were
    now under way. Octreotide Acetate Microspheres for Injection ( 注 射 用 醋 酸 奥 曲 肽 微 球 ) were undergoing BE pre-trials.
    Leuprorelin Acetate Microspheres for Injection ( 注射用醋酸亮丙瑞林微球 ) (three-month sustained-release) were undergoing
    BE pre-trials; Triptorelin Pamoate Microspheres for Injection ( 注 射 用 双 羟 萘 酸 曲 普 瑞 林 微 球 ) (three-month sustained-
    release) and Alarelin Acetate Microspheres for Injection ( 注射用丙氨瑞林微球 ) (one-month sustained-release) had obtained
    the notication of clinical trials, and active preparations had been made for the trials.

    2. Conventional preparations: There were a total of 27 projects under research, of which, two had been approved, four had been
    applied for production and ve had started clinical/BE study. Among them, Alogliptin Benzoate Tablets ( 苯甲酸阿格列汀片 )
    had been approved for production; Cetrorelix Acetate for Injection ( 注 射 用 醋 酸 西 曲 瑞 克 ) had been applied for registration
    in China and the United States, and was approved for marketing by China National Medical Products Administration in
    December 2021; Blonanserin Tablets ( 布南色林片 ) and Lurasidone Hydrochloride Tablets ( 盐酸鲁拉西酮片 ) had completed
    BE study and will be soon applied for production; and LZ001, an innovative anti-tumor drug was applied for clinical study
    (IND) in December 2021.

    3. Consistency evaluation: There were a total of 20 projects under research, of which, 4 had been approved and 10 were
    under application review. Among them, Omeprazole Sodium for Injection ( 注 射 用 奥 美 拉 唑 钠 ) and Fluvoxamine Maleate
    Tablets ( 马来酸氟伏沙明片 ) had been approved; Cefodizime Sodium for Injection ( 注射用头孢地嗪钠 ) was under review;
    Valsartan Capsule ( 缬 沙 坦 胶 囊 ) had completed submission of supplementary application materials; Imipenem and Cilastatin
    Sodium for Injection ( 注射用亚胺培南西司他丁钠 ) and Bismuth Potassium Citrate Capsule ( 枸橼酸铋钾胶囊 ) had been
    applied for approval; Rabeprazole Sodium Enteric-Coated Tablets ( 雷 贝 拉 唑 钠 肠 溶 片 ) had completed process verication
    and were in preparation for BE.




                                                                                                                                    41
 (2) Biologics

     There were a total 8 research projects, of which, one had been launched to the market; one had been applied for production;
     one was in phase III clinical study; two were in phase Ib/II clinical study and two were in phase I clinical study.

     Recombinant Human Choriogonadotropin alfa for Injection ( 注 射 用 重 组 人 绒 促 性 素 ) had been approved for launching in
     the market in China; Tocilizumab Solution for Injection ( 托珠单抗注射液 ) had been ocially applied for production and the
     application had been accepted; Phase III clinical trial enrollment of Recombinant SARS-CoV-2 Fusion Protein Vaccine ( 重 组
     新型冠状病毒融合蛋白疫苗 ) was coming to an end; Recombinant Humanized Anti-PD-1 Monoclonal Antibody for Injection
     ( 注 射 用 重 组 人 源 化 抗 PD-1 单 克 隆 抗 体 ) and Recombinant Anti-human IL-17A/F Humanized Monoclonal Antibody for
     Injection ( 重 组 抗 人 IL-17A/F 人 源 化 单 克 隆 抗 体 注 射 液 ) were undergoing phase Ib/II clinical trials; and Recombinant
     Tumor Enzyme Specic Interferon α-2b Fc Fusion Protein for Injection ( 注射用重组肿瘤酶特异性干扰素 α-2b Fc 融合
     蛋 白 ) and Recombinant Human Follicle Stimulating Hormone for Injection ( 重 组 人 促 卵 泡 激 素 注 射 液 ) were undergoing
     phase I clinical trials.

 (3) APIs and intermediates

     There were a total of 35 projects under research, of which Dalbavancin ( 达 巴 万 星 ) had completed verication and batch
     production, and Fluralaner ( 氟雷拉纳 ) was planned for verication and batch production.

 (4) Diagnostic reagents and equipment

     There were a total of 49 projects under research, of which, seven were in the clinical trial stage. For reagent development
     platform, four products including Novel Coronavirus (2019-nCOV) IgM Antibody Detection Kit (IgM 抗 体 检 测 试 剂 盒 )
     (enzyme-linked immunosorbent assay) (category III), seven Autoimmune Hepatitis-related Autoantibodies Detection Kit
     (magnetic barcode immunofluorescence luminescence) (category II), Mycoplasma Pneumoniae IgM Antibody Detection
     Kit (Chemiluminescence) (category III) and Dry Immunofluorescence Analyzer had been registered in China; seven
     projects including four diabetes specific autoantibodies, IgG4, Mycoplasma pneumoniae IgM (chemiluminescence) and
     Influenza Virus A+B antigen colloid gold had entered clinical trials, among which IgG4 and Mycoplasma pneumoniae IgM
     (chemiluminescence) had completed clinical trials and were being submitted for registration. As for the equipment R&D
     platform, the multi-channel dry fluorescence immunoanalyzer had been registered in China, and the second-generation
     irradiator model and the all-in-one instrument for molecular diagnostics had entered the stage of trial production.




42
                                                                                                                                                             Annual Report
                                                                                                                                                                     2021


(2). Basic information on main R&D projects
     √ Applicable □ N/A

                                                                                                                                                         Protected
                                                                                                                                                         traditional
     R&D projects (including                                     Registration                                                             Prescription    Chinese      R&D stage
                                   Name of drug (product)                                              Indications
     projects subject to GCE)                                    classication                                                             drug or not    medicine      (registration)
                                                                                                                                                          or not (if
                                                                                                                                                         applicable)
                                                                 Preventive
                                   The Recombinant SARS-
                                                                 biological
     V-01(COVID-19)              CoV-2                                          Used for treatment of novel coronavirus infection           Yes            No        Clinical trial
                                                                 products
                                   Fusion Protein Vaccine
                                                                 Class 1.1
                                   The Recombinant
                                                                 Therapeutic
                                   Humanized Anti-PD-1
     LZM009(PD-1)                                              biological       Advanced solid tumor                                        Yes            No        Clinical trial
                                   Monoclonal Antibody for
                                                                 products
                                   Injection
     Aripiprazole Microspheres     Aripiprazole Microspheres
                                                                 Chemical drugs
     for Injection (1-month        for Injection (1-month                         Mainly used to treat adult schizophrenia                    Yes            No        Clinical trial
                                                                 Class 2.2
     sustained-release)            sustained-release)
     Triptorelin Acetate           Triptorelin Acetate                            Metastatic prostate cancer, endometriosis (stages
                                                                 Chemical drugs                                                                                        Application for
     Microspheres for Injection    Microspheres for Injection                     I to IV), female infertility, pretreatment of uterine       Yes            No
                                                                 Class 2.2                                                                                             production
     (1-month sustained release)   (1-month sustained release)                    broids before surgery, precocious puberty.
                                                                                  It is indicated for the treatment of adult patients
                                   Recombinant Humanized
                                                                                  with moderately to severely active rheumatoid
                                   Anti-human IL-6R              Chemical drugs                                                                                        Application for
     LZM008(IL-6R)                                                              arthritis who have not responded adequately                 Yes            No
                                   Monoclonal Antibody           Class3.3                                                                                              production
                                                                                  to disease-modifying antirheumatic drugs
                                   Solution for Injection
                                                                                  (DMARDs).
                                                                 Chemical drugs                                                                                        Completed BE
     Blonanserin Tablets           Blonanserin Tablets                            Schizophrenia                                               Yes            No
                                                                 Class 4                                                                                               studies
                                                                                  Used for long-term treatment of chronic
     Tobramycin Solution for       Tobramycin Solution for       Chemical drugs   pulmonary infection caused by Pseudomonas                                            Application for
                                                                                                                                              Yes            No
     Inhalation                    Inhalation                    Class 2.4        aeruginosa in children with cystic brosis over 5                                     production
                                                                                  years old.
     Formoterol Fumarate           Formoterol Fumarate           Chemical drugs   Used to treat chronic obstructive pulmonary                                          Application for
                                                                                                                                              Yes            No
     Inhalation Solution           Inhalation Solution           Class 3          disease                                                                              production
     Formoterol Fumarate           Formoterol Fumarate           Chemical drugs   Used to treat bronchial asthma and chronic
                                                                                                                                              Yes            No        Clinical trial
     Inhalation Aerosol            Inhalation Aerosol            Class 2.2        obstructive pulmonary disease.
     Mometasone Furoate and        Mometasone Furoate and
     Formoterol Fumarate           Formoterol Fumarate           Chemical drugs   Used to treat asthma and chronic obstructive
                                                                                                                                              Yes            No        Clinical trial
     Dihydrate Inhalation          Dihydrate Inhalation          Class 3          pulmonary disease.
     Aerosol                       Aerosol
     Salmeterol Xinafoate and      Salmeterol Xinafoate and                       Used for routine treatment of reversible
                                                                 Chemical drugs                                                                                        Application for
     Fluticasone Propionate        Fluticasone Propionate                         obstructive airway diseases, including asthma in            Yes            No
                                                                 Class 4                                                                                               clinical trial
     Powder for Inhalation         Powder for Inhalation                          adults and children.
     Imipenem and Cilastatin                                                      Used to treat infection caused by one bacteria or
                                   Imipenem and Cilastatin       Chemical drugs                                                                                        Consistency
     Sodiumfor Injection (under                                                   more bacteria sensitive to imipenem in adults and           Yes            No
                                   Sodium for Injection          Class 4                                                                                               evaluation
     consistency evaluation)                                                      children.




                                                                                                                                                                                        43
(3). Drugs (products) led for regulatory approval and granted approval during the Reporting Period
     √ Applicable □ N/A

 ① Drugs (products) led for regulatory approval during the Reporting Period


                                            Registration
     Name of drug                                            Approval items                              Indications
                                            classication
                                                                           Used for long-term treatment of chronic pulmonary infection
                                            Chemical drugs Application for
     Tobramycin Solution for Inhalation                                    caused by Pseudomonas aeruginosa in children with cystic
                                            Class 2.4      production
                                                                           brosis over 5 years old.
     Formoterol Fumarate Solution for       Chemical drugs Application for
                                                                           Used to treat chronic obstructive pulmonary disease
     Inhalation                             Class 3        production
                                                                           Used to relieve bronchial asthma, chronic bronchitis,
     Terbutaline Sulphate Solution for      Chemical drugs Application for
                                                                           pulmonary emphysema and bronchospasm caused by other
     Nebulization                           Class 4        production
                                                                           pulmonary diseases.
                                                                           Used for treatment of moderate to severe active rheumatoid
                                            Chemical drugs Application for arthritis in adult patients with inadequate response to
     Tocilizumab Solution for Injection
                                            Class 3.3      production      DMARDs. Recombinant Humanized Anti-IL-6R Monoclonal
                                                                           Antibody for Injection combined with Methotrexate (MTX)
     Triptorelin Acetate Microspheres for   Chemical drugs Application for
                                                                           Localized, advanced, and metastatic prostate cancer
     Injection                              Class 2.2      production
                                                           Application
                                            Chemical drugs
     Ilaprazole Sodium for Injection                       for production Peptic ulcer bleeding
                                            Class 2
                                                           (Indonesia)
     Salmeterol Xinafoate and Fluticasone Chemical drugs Application for Used for routine treatment of reversible obstructive airway
     Propionate Powder for Inhalation     Class 4        clinical trial  diseases, including asthma in adults and children.
                                                                         Used for treatment of non-small cell lung cancer (NSCLC)
                                          Chemical drugs Application for
     LZ001 Tablets                                                       with ROS1 gene mutation and solid tumor with NTRK gene
                                          Class 1        clinical trial
                                                                         fusion
                                                                              1. Transplantation: organ transplantation; bone marrow
     Ciclosporin Soft Capsules                             Supplementary      transplantation
                                            Chemical drugs
     (consistency evaluation)                              application        2. Non-transplantation: endogenous uveitis; psoriasis; atopic
                                                                              dermatitis; rheumatoid arthritis; nephrotic syndrome
     Valsartan Capsules (consistency                         Supplementary
                                            Chemical drugs                    Used for treatment of mild to moderate essential hypertension.
     evaluation)                                             application
                                                                              Used for treatment of the following infections caused by
                                                                              sensitive organism: respiratory system infection; ear, nose, and
     Cefuroxime Sodium for Injection                         Supplementary    throat (ENT) infection; urogenital system infection; skin and
                                            Chemical drugs
     (consistency evaluation)                                application      soft tissue infection; bone and joint infection; other infections;
                                                                              and used for prevention of surgical and gynaecological
                                                                              diseases
                                                                              Used for treatment of chronic gastritis and mitigation of
     Bismuth Potassium Citrate Capsules                    Supplementary
                                            Chemical drugs                    gastralgia, heartburn and sour regurgitation caused by
     (consistency evaluation)                              application
                                                                              hyperacidity.
                                                                              Used for treatment of infections caused by methicillin-resistant
                                                                              staphylococcus aureus and other bacteria: septicemia, infective
     Vancomycin Hydrochloride for                            Supplementary
                                            Chemical drugs                    endocarditis, osteomyelitis, arthritis, supercial secondary
     Injection (consistency evaluation)                      application
                                                                              infection including burns and operative wound, pneumonia,
                                                                              lung abscess, empyema, peritonitis, and meningitis.




44
                                                                                                                Annual Report
                                                                                                                        2021


② Drugs (products) granted clinical approval during the Reporting Period


                             Registration
     Name of drug                                                               Indications
                             classication
     Formoterol Fumarate     Chemical drugs
                                            Used to treat bronchial asthma and chronic obstructive pulmonary disease.
     Inhalation Aerosol      Class 2.2
     Mometasone Furoate
     and Formoterol          Chemical drugs
                                            Used to treat asthma and chronic obstructive pulmonary disease.
     Fumarate Dihydrate      Class 3
     Inhalation Aerosol
     Aclidinium Bromide    Chemical drugs
                                          Used to treat chronic obstructive pulmonary disease
     Powder for Inhalation Class 2.2
                                          1) Used for treatment in women with anovulation (including polycystic ovary
                                          syndrome [PCOS]) and showing no response to Clomiphene Citrate.
                                          2) Used to stimulate the development of multiple follicles in women who
     Recombinant Human                    underwent controlled ovarian hyperstimulation by Assisted Reproductive
                           Chemical drugs
     Follicle Stimulating                 Technology (ART), such as In Vitro Fertilization (IVF), Gamete Intra-Fallopian
                           Class 3.3
     Hormone for Injection                Transfer (GIFT), and Zygote Intra-Fallopian Transfer (ZIFT).
                                          3) Used in patients who lack luteinizing hormone (LH) and follicle-stimulating
                                          hormone (FSH), or patients whose endogenous serum LH level is below 1.2IU/L.
                                          Combined use of LH and FSH is recommended to stimulate follicular development
                             Preventive
     SARS-CoV-2 Fusion       biological
                                              Used for treatment of novel coronavirus infection
     Protein Vaccine         products
                             Class 1.1
     Triptorelin Pamoate
                             Chemical drugs
     Microspheres for                       Localized, advanced, or metastatic prostate cancer
                             Class 2.2
     Injection
     Alarelin Acetate
                             Chemical drugs 1) Prostate cancer; 2) endometriosis, hysteromyoma, breast cancer, precocious
     Microspheres for
                             Class 2.2; 2.4 puberty, assisted reproduction, etc.
     Injection
                                              Used to control the blood glucose of adult patients with type 2 diabetes after pool
                             Therapeutic
                                              glycemic control with metformin and/or sulfonylureas based on diet control and
                             biological
     Semaglutide Injection                    exercise, and to reduce the risk of main cardiovascular adverse events (including
                             products
                                              cardiovascular death, non-fatal myocardial infarction or non-fatal stroke) to adult
                             Class 3.3
                                              patients with type 2 diabetes and cardiovascular diseases.
    Note: The Recombinant SARS-CoV-2 Fusion Protein Vaccine obtained approvals for phase III clinical primary trials countries
    including Philippines, Indonesia and Russia and obtained approvals for phase III clinical booster trials in Pakistan and
    Malaysia.




                                                                                                                                    45
 ③ Drugs (products) granted registration approval during the Reporting Period


                               Registration
      Name of drug                                                                            Indications
                               classication
                                                     1) Used to trigger nal maturity and luteinization of follicles after stimulating follicular
      Recombinant Human        Therapeutic           growth in women who underwent controlled ovarian hyperstimulation before receiving
      Choriogonadotropin       biological products   assisted reproduction technology such as IVF.
      alfa for Injection       Class 15              2) Used to trigger ovulation and luteinization after stimulating follicular growth in women
                                                     with anovulation or rare ovulation.
                                                     Used to treat patients with type 2 diabetes in addition to diet control and exercise; used
      Alogliptin Benzoate      Chemical drugs
                                                     to improve glycemic control in patients with type 2 diabetes based on diet control and
      Tablets                  Class 4
                                                     exercise in combination with Metformin Hydrochloride.
                                                     Used to prevent premature ovulation in patients receiving controlled ovarian stimulation
                                                     with assisted reproduction technology.
      Cetrorelix Acetate for   Chemical drugs
                                                     Used in combination with human menopausal gonadotropin (HMG) in clinical trials.
      Injection                Class 4
                                                     Limited combined use of this product with recombinant human follicle-stimulating
                                                     hormone (r-hFSH) shows that its ecacy is similar to the former.
                                                     Mainly used to: 1) treat peptic ulcer bleeding and anastomotic ulcer bleeding; 2) treat
                                                     acute gastric mucosal lesion under stress condition or caused by non-steroidal anti-
      Omeprazole Sodium for
                                                     inammatory drugs; 3) prevent upper gastrointestinal bleeding caused by severe diseases
      Injection (consistency Chemical drugs
                                                     (such as cerebral hemorrhage and severe trauma) under stress condition and after gastric
      evaluation)
                                                     surgery; 4) treat the following diseases when oral therapies are not applicable: duodenal
                                                     ulcer, gastric ulcer, reux esophagitis, and Zollinger-Ellison.
      Fluvoxamine Maleate
      Tablets (consistency     Chemical drugs        Used for treatment of 1) depression; 2) obsessive compulsive disorder
      evaluation)


(4). Cancellation of R&D projects or the failure to obtain approval for drugs (products) during the Reporting Period
     □ Applicable √ N/A

(5). R&D accounting policy
     √ Applicable □ N/A

     Expenditures on an internal research and development project are classified into expenditures on the research phase and
     expenditures on the development phase.

     Expenditures on the research phase shall be recognized in prot or loss for the current period when incurred.

     Expenditures on the development phase will be capitalized only when all of the following conditions are satisfied: it is
     technically feasible to complete the intangible asset so that it will be available for use or sale; the Company intends to complete
     the intangible asset and use or sell it; it can be demonstrated how the intangible asset will generate economic benefits,
     including proving that the intangible assets or the products produced by it will have markets, or the intangible assets for
     internal use will be useful; there are adequate technical, financial and other resources to complete the development and the
     Company is able to use or sell the intangible assets; and expenditures on the development phase attributable to the intangible
     assets can be reliably measured. The development expenditures that do not satisfy the above conditions shall be recognized in
     prot or loss for the current period.

     Our research and development projects enter the development stage after meeting the above conditions and forming the project
     through the technical and economic feasibility studies.

     Capitalized expenditures on the development phase are shown as development expenditures on the balance sheet and
     reclassied as intangible assets on the date the project meets the intended purpose.




46
                                                                                                               Annual Report
                                                                                                                       2021


    Capitalization conditions for specic research and development projects are as follows:

    ① For research and development projects that are not required to obtain clinical approvals, the period from the beginning of
       research and development to the pilot phase is treated as the research phase, and all expenditures shall be recognized in
       prot or loss for the current period when incurred; the period from the pilot phase to the obtaining of production approvals
       is treated as the development phase, and all expenditures shall be recognized as development expenditures and reclassied
       as intangible assets after the obtaining of production approvals.
    ② For research and development projects that require clinical approval, the period from the beginning of research and
       development to the obtaining of clinical approval is treated as the research phase, and all expenditures incurred shall be
       recognized in profit or loss for the current period when incurred; the period from the obtaining of clinical approval to
       the obtaining of production approval is treated as the development phase, and the expenditures shall be recognized as
       development expenditures and reclassied as intangible assets after the obtaining of production approval.
    ③ External technology transfer fees and the cost of purchasing clinical approvals can be recognized directly as development
       expenditures, and subsequent expenditures are accounted for in accordance with ① and ② above.
    ④ The Company reviews the latest research and development status of each project at the end of each year and if the research
       and development project no longer qualifies for the development stage, the corresponding development expenditure are
       recognized in prot or loss for the current period.
    ⑤ Where it is impossible to differentiate the expenditures on the research phase and the expenditures on the development
       phase, all the research and development expenditures are recognized in prot or loss for the current period

(6). R&D investment
     Horizontal comparison
     √ Applicable □ N/A
                                                                                                   Unit: 10,000 Yuan Currency: RMB
                                                               Proportion of R&D     Proportion of R&D
                                       R&D investment                                                        Ratio of capitalized
     Comparable peer companies                             investment to operating     investment to net
                                              amount                                                        R&D investment (%)
                                                                      income (%)              assets (%)
     Fosun Pharma                            400,300.00                     13.21                  10.82                   30.18
     Kelun Pharma                            151,629.35                       9.21                 11.23                   -0.73
     CR Double-Crane                          41,111.92                       4.83                  4.42                   29.21
     Humanwell Healthcare (Group)             93,661.07                       4.60                  8.70                   18.33
     North China Pharmaceutical            46,886.42                          4.08                  7.66                   74.56
     Average R&D investment in the same industry                                                                      146,717.75
     Proportion of R&D investment to operating income during the Reporting Period (%)                                      11.63
     Proportion of R&D investment to net assets during the Reporting Period (%)                                             9.17
     Ratio of capitalized R&D investment during the Reporting Period (%)                                                   24.47
    Note: 1. The data regarding comparable companies listed above are from each company's 2020 annual report;
          2. The average R&D investment in the same industry is the arithmetic average of the R&D investment of five
             comparable companies listed above.

    Statement on material changes in R&D investment and rationality of R&D investment proportion and capitalization proportion
    √ Applicable □ N/A

    During the Reporting Period, the Company's total R&D investment was RMB 1,849.82 million, a YoY increase of 46.75%,
    representing 11.63% of the total operating revenue and 9.17% of the total net assets, which was relatively high in the
    industry. In order to adapt to the changes in the demand of the pharmaceutical market and the continuous reform of the new
    drug research and development registration, the Company reconsidered its varieties under research and actively adjusted
    R&D strategy. While maintaining competitive products, the Company strengthened resource integration and internal
    control management. These moves improved R&D efficiency while kept R&D activities in an orderly manner as usual. The
    Company's current R&D investment is reasonable as it is well in line with the strategic layout and future development.




                                                                                                                               47
     Investment in major R&D projects
     √ Applicable □ N/A
                                                                                                       Unit: 10,000 Yuan Currency: RMB
                                                                                                       Proportion of R&D
                                                               R&D       Expensed     Capitalized
                                                                                                            investment to    Change
      R&D project                                         investment         R&D           R&D
                                                                                                         operating income       (%)
                                                             amount     investment    investment
                                                                                                                      (%)
      V-01(COVID-19)                                     49,111.94     17,694.65     31,417.29                     3.09   1,062.05
      LZM009(PD-1)                                        5,078.53      3,222.14      1,856.39                     0.32      39.35
      Aripiprazole Microspheres for Injection
                                                            4,856.54      4,856.54               0                   0.31     139.60
      (1-month sustained-release)
      Triptorelin Acetate Microspheres for Injection
                                                            4,403.32      3,361.52          1,041.8                  0.28      55.52
      (1-month sustained release)
      LZM008(IL-6R)                                       3,812.03        563.81      3,248.22                     0.24     -53.21
      Blonanserin Tablets                                   1,194.12      1,194.12               0                   0.08     128.90
      Tobramycin Solution for Inhalation                    2,268.58        313.58      1,955.01                     0.14      68.38
      Formoterol Fumarate Solution for Inhalation           1,571.91        497.87      1,074.05                     0.10      50.62
      Fluticasone Propionate Nebulizable Suspension           964.54        902.51           62.03                   0.06      27.68
      Formoterol Fumarate Inhalation Aerosol                  396.68        110.85          285.83                   0.02     -32.69
      Mometasone Furoate and Formoterol Fumarate
                                                              419.77         52.75          367.02                   0.03      26.46
      Dihydrate Inhalation Aerosol
      Salmeterol Xinafoate and Fluticasone
                                                            1,311.78        799.16          512.62                   0.08     533.11
      Propionate Powder for Inhalation
       Imipenem and Cilastatin Sodium for Injection
                                                              275.14          0.06          275.08                   0.02      62.73
     (consistency evaluation)
     Notes:1. The Projects listed above are the main R&D projects conducted by the Company; of which project Blonanserin
              Tablets is a Priority Review & Approval project.
           2. The main reason for the quite significant YoY increase in our R&D expenditure is that our R&D projects went into
              later clinical stages during the Reporting Period.


3.    Sales of drugs (products)
 (1). Analysis of main sales model
      √ Applicable □ N/A
      Please refer to Overview on the main businesses of the company during the Reporting Period part in this Chapter.

(2). Analysis of selling expenses
     Components of selling expenses
     √ Applicable □ N/A
                                                                                                      Unit: 10,000 Yuan Currency: RMB
                                                                                                      Proportion of current amount to
      Project name                                  Amount incurred in the current period
                                                                                                           total selling expenses (%)
      Business promotion expenses                                             447,776.46                                       89.08
      Employee compensation                                                    39,717.01                                        7.90
      Entertainment and travel expenses                                         6,529.77                                        1.30
      Business meeting expenses                                                 2,355.47                                        0.47
      Others                                                                    6,302.51                                        1.25
      Total                                                                   502,681.21                                      100.00




48
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                                                                                                                     2021


    Horizontal comparison
    √ Applicable □ N/A
                                                                                                 Unit: 10,000 Yuan Currency: RMB
                                                                                               Proportion of selling expenses to
     Comparable peer companies                                          Selling expenses
                                                                                                          operating income (%)
     Fosun Pharma                                                            846,394.32                                   27.93
     Kelun Pharma                                                            488,254.51                                   29.66
     CR Double-Crane                                                         302,941.81                                   35.62
     Humanwell Healthcare (Group)                                            366,880.40                                   18.01
     North China Pharmaceutical                                              276,414.83                                   24.05
     Total selling expenses of the Company during the Reporting Period                                              502,681.21
     Proportion of selling expenses to operating income during the Reporting Period (%)                                   31.61
    Note:The data regarding comparable companies listed above are from each company's 2020 annual report;

    Statement on material changes in selling expenses and rationality of selling expenses
    √ Applicable □ N/A

    During the Reporting Period, the Company's sales expenses were 5,026.81 million, representing 31.61% of the operating
    revenue, recording an increase compared with the previous year. The increase was mainly due to more efforts to promote
    products and brands, and an increase in sales expenses in prescription drugs which recorded significant sales growth during
    this period. Looking fowward, the Company will continue to deepen the reform of the marketing system to optimize sales
    channels and increase the cost eciency for high protability.

4. Others
   □ Applicable √ N/A


(V) Analysis of investments
    Overall analysis of external equity investment
    √ Applicable □ N/A

    During the Reporting Period, the Company carried out strategic investments in accordance with our development plans; the
    main investment projects are as follows:

1. Major equity investment
   √ Applicable □ N/A

(1) Livzon Group acquired 40% equity interest of Tianjin Tongrentang

    The Resolution on Acquisition of 40% Equity Interest in Tianjin Tongrentang Group Co., Ltd. by the Controlling Subsidiary
    Livzon Group was considered and approved at the 43rd Meeting of the 7th Session of the Board on 22 March 2021, pursuant
    to which Livzon Group, the controlling subsidiary of the Company, was approved to enter into the Share Transfer Agreement
    in Relation to Tianjin Tongrentang Group Co., Ltd. with Tianjin Tasly Healthcare Industry Investment Partnership (Limited
    Partnership) * ( 天津天士力健康产业投资合伙企业(有限合伙)) (“Tianjin Tasly”). Accordingly, Livzon Group shall
    use its own funds of RMB724 million to acquire 44,000,000 shares of Tianjin Tongrentang Group Co., Ltd.* ( 天 津 同 仁 堂 集
    团股份有限公司 ) (“Tianjin Tongrentang”) held by Tianjin Tasly, representing 40% of the total number of shares of Tianjin
    Tongrentang.




                                                                                                                              49
      Tianjin Tongrentang is principally engaged in the R&D, production and sales of Chinese patent medicines. Tianjin Tongrentang
      has a stable operating performance with unique products and promising growth potential. On 9 March 2021, the Tianjin
      Securities Regulatory Bureau announced its acceptance of the application for counselling of the initial public offering of its
      shares (and listing on the ChiNext Board of Shenzhen Stock Exchange). Upon completion of the Transaction, Livzon Group
      will not only have certain synergy with Tianjin Tongrentang in respect of the development of Chinese medicine business but
      will also be able to realize the corresponding investment income through cash dividends or initial public oering and listing of
      Tianjin Tongrentang. The Transaction is not expected to have a material impact on the current and future nancial position and
      operating results of the Company and Livzon Group. After completion of the Transaction, the financial statement of Tianjin
      Tongrentang will not be consolidated in the nancial statements of the Company and Livzon Group and will only be treated as
      an investment by the Company and Livzon Group.

      On 27 April 2021, Livzon Group obtained the“Conrmation Letter on Securities Transfer and Registration ( 证 券 过 户 登 记
      确 认 书 )”from China Securities Depository and Clearing Corporation Limited, and Livzon Group has completed the transfer
      and registration procedures in relation to the Transaction. In addition, during the share transfer period of the Transaction,
      Tianjin Tongrentang implemented the equity distribution for the year 2020 (distribution of cash dividends), and pursuant to
      the Agreement, Tianjin Tasly shall pay Livzon Group the full amount of the cash dividends received during the share transfer
      period. On 27 April 2021, Livzon Group has received the aforesaid cash dividends which amounted to a total of RMB40.04
      million.

      Tianjin Tongrentang obtained the Notice on the Acceptance of Application Documents of Tianjin Tongrentang Group Co., Ltd.
      in Connection with the Listing of Shares from Initial Public Offering on the Chinext Board (Shen Zheng Shang Shen [2021]
      No.265) on 28 June 2021, which states that the Shenzhen Stock Exchange has accepted the application documents of Tianjin
      Tongrentang in connection with the listing of shares from initial public offering on the ChiNext Board. However, it remains
      uncertain whether such application would be approved by the Shenzhen Stock Exchange.

      The Shenzhen Stock Exchange has suspended the review of listing of Tianjin Tongrentang on 26 January 2022, as CSRC
      has initiated an investigation against ShineWing Certified Public Accountants (Special General Partnership), the accountant
      engaged by Tianjin Tongrentang for the initial public offering of its shares and listing on the ChiNext Board.The suspension
      of the review of the IPO application of Tianjin Tongrentang will not have significant impact on the production and operation
      activities of the Company. There is still uncertainty about the time for the resumption of review of Tianjin Tongrentang's IPO
      application and whether it will eventually be approved by the Shenzhen Stock Exchange.

      Please refer to the relevant announcements disclosed by the Company on 23 March 2021, 7 April 2021, 28 April 2021, 1 July
      2021 and 8 February 2022.

 (2) Overall relocation and expansion project of Sichuan Guangda

       On 6 March 2019, Livzon Group, the controlling subsidiary of the Company, entered into the“Investment Agreement for the
       Overall Relocation and Expansion Project of Sichuan Guangda Pharmaceutical Manufacturing”(《 四 川 光 大 制 药 整 体 搬
       迁 调迁 扩 建 项 目 投 资 协 议 书 》) (the“Investment Agreement”) and the Supplemental Agreement I with Sichuan Chengdu
       Pengzhou Municipal People's Government ( 四川省成都市彭州市人民政府 ). Pursuant to the Investment Agreement, Livzon
       Group will inject capital of RMB646 million for investment in construction of the overall relocation and expansion project (the
     “Project”) of Sichuan Guangda, a wholly-owned subsidiary of Livzon Group. Pursuant to the Supplemental Agreement I,
       Pengzhou Municipal People's Government has agreed to pay a compensation for demolition of RMB90 million and grant total
       incentive of not more than RMB125.8 million for the construction of new plant to Livzon Group.

      As at 31 December 2021, the total investment of the specic contracts entered into for the Project amounted to RMB395.5607
      million, and the sum of subsidies received from government authorities at various levels amounted to RMB 101.1799 million,
      the construction works for the warehousing system and the QC main body were completed, the construction works for the
      main body of the extraction workshop and the pre-treatment workshop were implemented, and the foundation construction
      works for the granulation workshop, the comprehensive preparation workshop and the packaging workshop were implemented,
      and the overall Project was smooth in progress.




50
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                                                                                                                         2021


(3) Investment in Beijing Innite Intelligence Pharma Technology Co., Ltd.

    On 15 January 2021, Zhuhai Livzon Pharmaceutical Equity Investment Management Co., Ltd. * ( 珠 海 市 丽 珠 医 药 股 权 投
    资 管 理 有 限 公 司 ), a wholly-owned subsidiary of Livzon Group, a controlling subsidiary of the Company, entered into the
    Capital Injection Agreement of Beijing Innite Intelligence Pharma Technology Co., Ltd. with original shareholders of Beijing
    Innite Intelligence Pharma Technology Co., Ltd. * ( 北 京 英 飞 智 药 科 技 有 限 公 司 ) (“Innite Intelligence Pharma”),
    pursuant to which Zhuhai Livzon Pharmaceutical Equity Investment Management Co., Ltd. contributed RMB 20 million to
    subscribe for registered capital of RMB 158,730 of Infinite Intelligence Pharma. After the capital injection, Zhuhai Livzon
    Pharmaceutical Equity Investment Management Co., Ltd. held 11.7647% equity interest in Infinite Intelligence Pharma.
    Innite Intelligence Pharma is principally engaged in the articial intelligence empowered drug design.

(4) Investment in Haisong Precision Parts and Components (Taicang) Co., Ltd.

    In March 2021, Shanghai Frontier, a controlling subsidiary of the Company, entered into the Investment Agreement in Relation
    to Haisong Precision Parts and Components (Taicang) Co., Ltd. with Haisong Precision Parts and Components (Taicang) Co.,
    Ltd. * ( 海 嵩 精 密 零 部 件( 太 仓 ) 有 限 公 司 ) (“Haisong Precision”), pursuant to which Shanghai Frontier subscribed
    for registered capital of RMB3.23 million of Haisong Precision, accounting for 35% equity interest of Haisong Precision.
    Haisong Precision is principally engaged in the production, processing and sale of plastic products, molds, and class I and II
    medical devices. The investment will strengthen the R&D strength of the Company in inhalation administration system, which
    conforms to the strategic development goal of the Company.

(5) Establishment of Shanghai Liyu Biopharmaceutical Technology Co., Ltd.

    In March 2021, Shanghai Frontier, a controlling subsidiary of the Company, entered into the Shareholder Agreement with
    Livzon Group, pursuant to which both parties jointly invested and established Shanghai Liyu Biopharmaceutical Technology
    Co., Ltd. * ( 上 海 丽 予 生 物 医 药 技 术 有 限 责 任 公 司 ) in cash at the registered capital RMB3 million, of which Shanghai
    Frontier and Livzon Group contributed RMB1.35 million and RMB1.65 million in proportion of 45% and 55% of the
    registered capital, respectively. Shanghai Liyu Biopharmaceutical Technology Co., Ltd. is principally engaged in technological
    services, technological development and related business within the scope of pharmaceutical technology.

(6) Establishment of Zhuhai Liye Biotechnology Co., Ltd.

    In February 2021, Zhuhai Livzon Diagnostics Inc. * ( 珠 海 丽 珠 试 剂 股 份 有 限 公 司 ), a subsidiary of Livzon Group, a
    controlling subsidiary of the Company, established Zhuhai Liye Biotechnology Co., Ltd. * ( 珠海市丽业生物技术有限公司 )
    at the registered capital of RMB50 million, of which Zhuhai Livzon Diagnostics Inc. accounted for 100% of the registered
    capital. Zhuhai Liye Biotechnology Co., Ltd. is principally engaged in R&D, production, and sales of medical devices.

(7) Establishment of Zhuhai Livzon Pharmaceutical Import and Export Co., Ltd.

    In July 2021, Zhuhai Livzon Pharmaceutical Import and Export Co., Ltd. was established as a wholly-owned subsidiary of
    Livzon Group, a majority-owned subsidiary of the Company, with a registered capital of RMB 10 million, to mainly engage in
    wholesale, import and export of drugs.

(8) Establishment of Changsha Lijin Baokang Medical Technology Co., Ltd.

    In August 2021, Changsha Lijin Baokang Medical Technology Co., Ltd. was established by Livzon Diagnostics, a majority-
    owned subsidiary of Livzon Group, a majority-owned subsidiary of the Company, with a registered capital of RMB 1 million,
    to mainly engage in R&D, production and sale of class I, class II and class III medical apparatuses and instruments.

(9) Establishment of Zhuhai Livzon Traditional Chinese Medicine Modernization Technology Co., Ltd.

    In August 2021, Zhuhai Livzon Traditional Chinese Medicine Modernization Technology Co., Ltd. was established as a
    wholly-owned subsidiary of Livzon Group, a majority-owned subsidiary of the Company with a registered capital of RMB 30
    million, to mainly engage in production, wholesale, import and export of drugs.




                                                                                                                                  51
(10) Investment in Beijing Luzhu Biotechnology Co., Ltd.

     In August 2021, Zhuhai Livzon Pharmaceutical Equity Investment Management Co., Ltd., a wholly-owned subsidiary
     of Livzon Group, a majority-owned subsidiary of the Company, invested RMB 30 million to purchase Beijing Luzhu
     Biotechnology Co., Ltd, accounting for 1.3951% of its registered capital of RMB 2,332,815. The company is mainly engaged
     in development and transfer of technologies, and provision of services related to biological products, drugs, diagnostic reagents
     and medical instruments.

(11) Investment in Shanghai Keentai Biomedical Technology Co., Ltd.

     In September 2021, Zhuhai Livzon Pharmaceutical Equity Investment Management Co., Ltd., a wholly-owned subsidiary of
     Livzon Group, a majority-owned subsidiary of the Company, invested RMB 20 million to participate in Pre-A round nancing
     of Shanghai Keentai Biomedical Technology Co., Ltd., accounting for 4.88% of the total nancing. The company is principally
     engaged in technological development, technology service, technology transfer, technology consulting and drug R&D in elds
     of biotechnology and pharmaceutical technology.

 2. Major non-equity investment
    □ Applicable √ N/A

 3. Financial assets measured at fair value
    √ Applicable □ N/A

     As of the end of the Reporting Period, for details of the Company's nancial assets measured at fair value, please refer to Note
     9“ Fair Value”in Chapter X“ Financial Statements”.

 4. Progress of Material Asset Restructurings of the Company during the Reporting Period
    □ Applicable √ N/A


(VI) Sale of major assets and equity
     □ Applicable √ N/A


(VII) Analysis of major controlled and invested companies
     √ Applicable □ N/A
                                                                                                                                     Unit: 10,000 Yuan
                      Nature of                                                Registered                                         Operating
     Company                               Main product and service                         Asset size   Net assets   Revenues                Net prot
                      business                                                    capital                                             prot
                                  R&D, production and sales of oral liquids,
                                  hormone tablets, aerosol (hormone-
     Taitai                       containing), inhalation preparations
                      Industry                                                    10,000    56,299.86    29,267.82    22,281.36   10,316.83   9,227.15
     Pharmaceutical               (solution for inhalation) (hormone-
                                  containing), hormone nasal spray, and
                                  TCM extraction workshop.
                                  Wholesale and retail of skincare products,
                                  cosmetics, and other daily necessities;
     Taitai
                      Industry    domestic business, material supply and             500       178.84       124.34       80.74        -6.15     -21.60
     Biotechnology
                                  marketing industry, R&D of health care
                                  products.




52
                                                                                                                                   Annual Report
                                                                                                                                           2021


                   Nature of                                                 Registered                                            Operating
Company                                 Main product and service                           Asset size    Net assets    Revenues                Net prot
                   business                                                     capital                                                prot
                               Powder injection (including penicillin),
                               tablets, hard capsules, APIs, and sterile
                               APIs. Import and export businesses and
Haibin Pharma      Industry    domestic trade (excluding commodities            70,000    223,846.22    123,957.73    168,852.00   31,642.97   28,641.75
                               under exclusive rights, commodities
                               under special government control, and
                               monopolized commodities).
                               Manufacturing and sale of pharmaceutical
Xinxiang Haibin Industry       products, intermediates and other chemical       10,000     42,854.45     24,198.91     63,588.06    7,346.68    6,575.02
                               products.
                               Production and sale of self-produced
Health                         healthcare food, traditional Chinese
                   Industry                                                  HKD 7,317     13,085.35      9,815.33      3,914.58     682.75      401.30
Pharmaceutical                 medicine decoction pieces, and drug
                               products.
                               R&D of new pharmaceutical products,
                               health care products, medical devices,
Shanghai                       diagnostic reagents, pharmaceutical
                   Industry                                                      5,000     18,513.32     10,184.61     10,970.48    2,329.97    2,160.77
Frontier                       intermediates, and provision of relevant
                               technical consulting, technical service and
                               technical transfer
                               Investment in industry, domestic
                               commerce, material supply and marketing
Hiyeah Industry    Commerce                                                     17,800        659.46        607.84       280.38       -57.60      -57.60
                               industry, and economic information
                               consulting
                               Wholesale of health care products, ginseng
Joincare Daily-                tea, ginseng lozenges, ginseng capsules,
                   Commerce                                                      2,500      3,860.41      3,854.08             -      95.75       95.29
Use                            and stereotyped packaged food (including
                               health-care food)
                               Screening of human disease-specic
                               genes, R&D, production, sale and
                               technical consulting service of genetic
Taitai Genomics Industry       engineering drugs and diagnostic reagents,        5,000      3,629.66      3,629.66          6.63        6.53        6.53
                               wholesale of medical devices, and in vitro
                               diagnostic reagents (except for diagnostic
                               reagents under special management)
Appraisal
                   Commerce Forensic evidence identication                            -     1,023.64        945.17       190.52       -54.65      -56.22
institution
Zhuhai                         Technical R&D and application of
                   Industry                                                      6,587              -             -            -     949.88      948.95
Jiankangyuan                   biomedical products
                               Investment in power, industry, domestic
Fenglei Electric
                   Investment commerce, and material supply and                 10,000     29,186.45     14,190.84             -   -3,193.67   -3,193.67
Power
                               marketing industry
Hong Kong
                   Investment Investment and trade                              HKD 1      32,345.55        648.66       289.51      240.40      214.42
Health
                               R&D, production and sale of pharmaceutic
                               preparations, chemical APIs, biological
Jiaozuo Joincare Industry                                                       50,000    207,954.53    153,764.56    140,642.76   21,634.98   19,267.40
                               APIs, pharmaceutical intermediates, and
                               biological products.




                                                                                                                                                     53
                        Nature of                                                  Registered                                           Operating
     Company                                   Main product and service                          Asset size   Net assets   Revenues                 Net prot
                        business                                                      capital                                               prot
     Topsino            Commerce Investment and trade                             HKD89,693     162,517.08    81,227.09            -    21,191.45   21,191.45
     Health
                        Investment According to law where it was registered            USD5       2,594.51     2,594.51            -            -           -
     Investment
                                    R&D, production, storage, transport
                                    and sale of chemical APIs (including
                                    intermediates) and pharmaceutic
                                    preparations Import and export
     Joincare Haibin    Industry                                                      50,000     66,857.71    45,349.43    30,977.60    17,343.57   14,570.05
                                    businesses and domestic trade (excluding
                                    commodities under exclusive rights,
                                    commodities under special government
                                    control, and monopolized commodities)
                                    R&D, production and sale of formula
     Joincare Special
                        Industry    food, health-care food and food for special        2,000      1,354.85       232.54            -       -84.43      -66.48
     Medicine Food
                                    medical use
                                    Drug R&D, production, manufacturing
     Livzon Group       Industry                                                      93,787 2,237,191.56 1,431,102.48 1,206,386.33    226,699.00 195,210.12
                                    and sale
     Note: 1. The companies listed above are companies where the Company directly or indirectly held 100% equity interest,
              except for Livzon Group, Zhuhai Jiankangyuan, and Shanghai Frontier; financial data thereof are data of individual
              accounting statements and that attributed to parent companies; as there are transactions between subsidiaries or
              between a subsidiary and the Company, data of individual accounting statements is not separately analyzed.
           2. Zhuhai Jiankangyuan completed the industrial and commercial deregistration on 8 September 2021.
           3. For business conditions of Livzon Group, please refer to the 2021 Annual Report of Livzon Group.


(VIII) Structured entities controlled by the Company
     □ Applicable √ N/A


VI Discussion ad analysis of the Company's future development

 (I) Industry landscape and trend
     √ Applicable □ N/A
     Please refer to the“Basic information on industry”part in this chapter.


 (II) Company's strategies for business development
     √ Applicable □ N/A
     Taking scientific and technological innovation as a strategic priority, executing our dual-drive strategy of developing
     platforms of both innovative medicines and high-barrier complex preparations, we have been evolving into an industry-
     wide influential innovative pharmaceutical enterprise paying great attention to people's livelihood and actively undertaking
     social responsibilities. Over the years, the Company has been committed to developing itself in the pharmaceutical field,
     and has grown into a comprehensive pharmaceutical enterprise covering multiple areas including chemical drug preparation,
     chemical APIs and intermediates, traditional Chinese drug preparation products, diagnostic reagents and equipment. In the
     future, the Company will continue to increase R&D investment to improve its research and innovation capacity, accelerate the
     optimization and adjustment of its product structure, fully leverage its existing market advantages, and actively deepen the
     reform of the marketing system, to promote its sustainable and steady business growth.




54
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                                                                                                                         2021


(III) Business plans
    √ Applicable □ N/A

    The main business plans for each operation unit of the Company in 2022 are set as follows:

1. R&D Center

    R&D and innovation are the hard power of the Company to maintain sustainable development. The Company will, on
    the one hand, define the strategic direction for future R&D efforts, and screen and evaluate key high-barrier varieties, to
    diversify the R&D variety pipeline; and will, on the other hand, promote product transformation, and effectively advance the
    research and clinical development of existing core products, to accelerate the marketing process. (1) Strategic layout of R&D
    and innovation: In recent years, focusing on inhalant preparations, the Group has conducted in-depth research on a few of
    carefully selected new products with high clinical value and wide market space, and has achieved good results. In the future,
    under the existing R&D pipeline, the Group will focus on the following R&D areas: 1) Inhalation preparations: continue to
    enrich the pipeline and layout of inhalation preparations; 2) Complex injections: Complex injections are mainly micro and
    nano injections, with broad clinical application prospect and high technical complexity, and will be added to the high-barrier
    complex preparation R&D platform of the Group; 3) New drug delivery devices: drugs for respiratory treatment are usually
    delivered through combined medical instruments with a complex structure, thus posing high requirements on the structural
    design, performance and quality control. The Group will develop supporting drug delivery devices based on the progress of
    R&D of drugs for respiratory diseases, improve the industrial chain of inhalation preparations, and enhance the added value
    and core competitive strengths of products to be marketed. (2) Transformation of existing products under R&D: Currently,
    the Group has 179 products under R&D, including 40 high-barrier complex preparations. In 2022, the Group will make major
    eorts to apply for marketing authorization for Tobramycin Solution for Inhalation ( 妥 布 霉 素 吸 入 溶 液 ), and strive to get
    it included in China's National Reimbursement Drug List. At the same time, the Group will make vigorous efforts to assist
    and promote global multi-center phase III clinical trials of V-01, and strive to complete the trials and apply for marketing
    authorization as soon as possible. This will endow the Company with the qualification and rich experience in conducting
    global multi-center clinical trials for more products in the future.

2. Sales Center

    In 2021, the Group secured outstanding achievements in selling prescription medicines. In the future, with the transformation
    of more products developed, especially the production and marketing of new respiratory products, the Company will see a
    more complete product line in the prescription drug sector. Against the backdrop of increased incidence of respiratory diseases
    and steady increase of clinical demand, the marketing and promotion of prescription medicines should be backed by the
    Group's strong R&D strength and efficient innovation. Taking the industrial and market opportunity that three blockbuster
    products, including Budesonide Suspension for Inhalation ( 吸入用布地奈德混悬液 ) have been selected for centralized drug
    procurement organized by the State and that Levosalbutamol Hydrochloride Nebuliser Solution ( 盐 酸 左 沙 丁 胺 醇 雾 化 吸
    入 溶 液 ) has been included in the list of drugs for negotiation led by National Health Security Administration, the Company
    will make continuous eorts to enable its inhalation preparations to enter more hospitals and serve more patients. To this end,
    the Group will, in terms of marketing prescription medicines in the new year, focus on the following five aspects: strengthen
    team building and improvement of comprehensive quality, continue to expand the terminal sales team, continuously attract
    excellent talents to join the sales team, take brand building as the goal, and improve the practical capability and comprehensive
    quality of marketing teams; strengthen supervision, appraisal, and management by objectives, strengthen integration of
    terminal resources, focus on establishing national benchmark areas, benchmark hospitals and benchmark sales teams, include
    key hospitals above grade II in the appraisal system, and comprehensively enhance the coverage and fulfillment rate of
    evaluation indicators; seize the opportunity that three inhala tion preparation products have been successfully selected for
    centralized drug procurement organized by the State, be prepared in business, production, terminal and other links, and quickly
    increase market share and raise brand awareness in all aspects; promote digital marketing, continue to advance construction
    of digital marketing platform and support for terminal market activities, effectively combine online and offline methods, and
    enhance brand recognition on the doctor side and patient side; strengthen access to the National Reimbursement Drug List
    and policy adjustment, follow up in real time national medical reform-related policies, strengthen drug post-marketing and
    pharmacoeconomic research, and actively cope with subsequent medical insurance adjustment.


                                                                                                                                  55
     In the past year, by grasping the market opportunities in the API and intermediates segments, the Group ensured continued
     sales growth. In the future, in order to further excel in API and intermediates marketing, the Group will: 1) strengthen building
     of the sales team: make full use of OKR and strengthen management by objectives, to build a vigorous and highly efficient
     sales team; 2) continue to promote strategic cooperation: pursue further development in segments, actively develop customer
     resources and maintain cooperative partnerships, give full play to the strength of the Company's brand, and establish long-
     term, stable and win-win cooperation with strategic partners; 3) subdivide the terminals of the entire industrial chain, with
     a focus on that of key varieties, conduct in-depth research and analysis of domestic and foreign markets, explore potential
     customer resources, and continuously increase the market share at home and abroad; 4) accelerate the R&D and production
     transformation of high-margin varieties, enrich the product structure, foster a complete ecological industry chain, and enhance
     the visibility of the brand of Joincare API series.

     Healthcare products, as the pr oducts firstly developed by the Group, are an important part of the Group's entire product
     package. In the future, the Group will deepen reform of the marketing mode for healthcare products and OTC products and
     further promote digital marketing, to enhance the brand visibility and influence among users through three major media
     platforms. TikTok platform will be mainly used to increase the exposure of products, enhance the brand visibility and access by
     consumers; Xiaohongshu will be used to maintain the brand reputation and attract consumers; Toutiao will be used to activate
     and enhance the stickiness of consumers utilizing the influence of authoritative figures. Through mental and effect input, the
     Group will increase the transformation efficiency of communication, achieve the integration of brand effect and sales results
     and empower oine and online marketing transformation. The Company will make in-depth channel distribution through O2O
     reform, and focus on integrating diversied resources and boosting sales by resource empowerment.

 3. Production Center

     The Production Center will persist in ensuring workplace safety and product quality, proceed with establishment of a quality
     m anagement system, and implement product quality-centered risk control, with a focus on checking raw and auxiliary
     materials, production sites and production process, to detect workplace safety risks according to the six systems in GMP, at
     the same time, continuously optimize the production process by introducing advanced technology, and improve the employee
     training system to enhance the professional skills of employees so as to ensure uniform and stable product quality; persist in
     reducing costs and improving efficiency through introducing advanced technology and equipment, production optimization,
     system improvement and lean management, to effectively improve the production and operation level; adhere to green
     development, continue to uphold and promote the concept of green, healthy and sustainable development, enhance the
     environmental protection and quality standards and requirements, set environmental protection targets, strengthen monitoring
     of energy consumption, pollutant emissions and other environmental information in the production and operation processes,
     and effectively implement energy conservation, emission reduction and green production. It will persist in optimizing
     production capacity, advance the construction of Haibin factory in Pingshan and the new production line as planned, follow up
     the establishment of supporting facilities and capacity layout planning, and improve the technology transformation capacity of
     new products to meet the increased market demand for new and existing products.




56
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                                                                                                                         2021


4. Functions and strategies

    The Company's functions and strategies of 2022 are mainly focused on the following ve aspects: 1) organizational structure:
    further perfect the organizational structure and institutional setting of subsidiaries of the Group, strengthen internal control
    of the Group and its subsidiaries, comprehensively enhance the management eciency of the Group and its subsidiaries, and
    promote lean management; 2) talent team building: conduct a comprehensive reform of the compensation system, clarify
    the career development channel and ranks within the compensation system and corresponding incentives, implement the
    management by objective (MBO) system with OKRs and KPIs in parallel, conduct quarterly rolling dynamic tracking and
    adjustment, build a talent echelon and introduce high-end talents to ensure the stability of the core talent team; 3) internal
    and external cooperation: pay close attention to innovation of cutting-edge technologies and industry development, actively
    leverage the resource advantages brought out by internal and external business cooperation, and invest in and introduce
    innovative products and technologies to improve the Company's strategic layout; 4) cultural development: actively create
    a healthy and positive work culture and atmosphere, constantly optimize the working environment, boost the enthusiasm
    and subjective initiative of employees, improve the sense of happiness and belonging of employees in work and life, so that
    employees and the Company can develop together; 5) social responsibility: in the pandemic era, the Company will actively
    fulll its social responsibilities by contributing to the ght against the pandemic, and will, at the same time, promote the high
    quality and sustained development of the Company.


(IV) Potential risks
    √ Applicable □ N/A

1. Risk of changes in industrial policies

    The pharmaceutical manufacturing industry is significantly affected by changes in industrial policies. The pharmaceutical
    industry will face great challenge in development in the future with continuous deepening of medical reform, advancement of
    supply-side structural reform in the industry, revision of Drug Administration Law, acceleration of consistency evaluation of
    generic drugs, adjustment of the new edition of Medical Insurance Catalog, expansion of minimum procurement commitment,
    and other industrial policies that have been successively launched. In 2022, the Company's key product Meropenem for
    Injection ( 注 射 用 美 罗 培 南 ) was included in the seventh batch of centralized drug procurement organized by the State. This
    will have a great impact on the sales price and market share of this product.

    Response measures: The Company will pay close attention to industry dynamics and reform, cope with major changes in
    policies of the pharmaceutical industry through early layout, transformation and compliance, and actively strengthen new
    product R&D and innovation and constantly improve its core competitive strengths. Meanwhile, the Company is actively
    engaged in the access to the national reimbursement drug list and negotiation. In the adjustment of the list in 2021, the
    Company's product Ilaprazole sodium for injection ( 注 射 用 艾 普 拉 唑 钠 ) has been renewed through negotiations and
    continues to be included in the New Medical Insurance Catalogue.This will improve the clinical value of the product and
    benefit more patients. At present, this product has a low coverage rate of grade hospitals, so the price reduction will benefit
    more patients. The Company will continue to increase the coverage of hospitals and sales, to realize the objective of“price for
    quantity”, so as to reduce the impact of price adjustment on the Company's steady growth. Moreover, the centralized drug
    procurement is becoming a regular practice. In 2021, three inhalation preparation products of the Company were successfully
    included into the fth batch of centralized drug procurement organized by the State. This will help the Company rapidly open
    up the domestic market of inhalation preparation products and increase the market share. In the face of the upcoming seventh
    batch of centralized drug procurement and the possible impact on the business performance, the Company will continue to
    strengthen innovation and improve its competitiveness, to ensure sound operation. With the Company's new high-barrier
    complex preparations, represented by inhalation preparations, appearing on the market one after another, commercialization
    will gradually enter a stable contribution period. The Company's product structure will be further optimized, and the reliance
    on a single product will also gradually reduce.




                                                                                                                                  57
 2. Market risk

     With advancement of supply-side structural reform in the pharmaceutical manufacturing industry and two invoice policy in
     circulation domain, pharmaceutical market structure is deeply changed. With the gradual standardization and centralization
     of the market, competition in the pharmaceutical industry becomes increasingly fierce. Affected by increasingly stricter drug
     regulation, policy-based drug price reduction, price cutting during bidding, medical insurance premium control, and minimum
     procurement commitment of the pharmaceutical industry in current stage, bid winning price of drugs will be further lowered,
     competition among enterprises in the industry will be intensified, and price war will occur frequently, thus the Company will
     be at the risk of drug price reduction.

     Response measures: The Company will establish a more reasonable market system through strict compliance operation so
     as to maintain its dominant position and core competitive strengths, and ensure that it can achieve sustainable and steady
     development and improve its protability by reinforcing marketing. Meanwhile, the Company will oset the impact of product
     price reduction by means of price supplement based on quantity, and optimize technical process and reduce production costs
     through internal exploration and transformation. Moreover, the Company will speed up the R&D and marketing of new
     products, spread risks of the Company while expanding the range of existing products in segment markets, improve sales and
     form new prot growth point by increasing product varieties in the future.

 3. Risk of environmental protection

     The Company is a comprehensive pharmaceutical manufacturing enterprise. During production, it implements relevant
     chemical synthesis process and uses a large number of acid and alkali and other chemical components, which are inammable,
     explosive, toxic, irritant and corrosive, and have hidden hazards of fire, explosion and poisoning, posing certain risks to the
     production and operation of the Company. As environmental protection policies and regulations have been constantly issued in
     recent years, environmental protection standards have become more stringent, and the state has strengthened its control over
     pollutants, risks of environmental protection of the Company are increasing.

     Response measures: The Company has always obeyed the safety work concept of“Putting People First”and the guideline
     of“safety first, Precaution Crucial and Comprehensive Treatment”. It will strengthen the construction of safe production
     infrastructure and ensure a sound environment for safe production of the Company through regular internal audit of safety
     and environment systems and employee safety education and training. The Company will carry out discharge after treatment
     and reaching standards in accordance with environmental protection provisions, actively accept supervision and inspection
     of environmental protection authorities, and try to reduce emission and increase expenditures in environmental protection by
     improving production process and promptly updating environmental protection technology.

 4. Risk in price and supply of raw materials

     There is a larger fluctuation in the supply price of some raw materials of the Company due to changes in material prices,
     especially the materials of traditional Chinese medicine, causing greater volatility or rise in production costs of the Company.
     Meanwhile, the quantity and category of raw material suppliers of the Company are various, thus quality of final products of
     the Company will be directly aected by the selection of raw material suppliers and the guarantee and control of quality of raw
     materials.

     Response measures: In terms of selection of suppliers, the Company will conduct an open tendering and bidding based on the
     principle of selecting qualified suppliers, strengthen audit of suppliers, and eliminate the adulteration of adverse suppliers.
     The Quality Assurance Department and Supply Department of the Company will directly conduct process control of products
     provided by suppliers of key raw materials and carry out quality inspection and control of nal products.




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                                                                                                                        2021


5. Risk of R&D for new drugs

   New drug R&D is characterized by high input, high risk and long period. The State has frequently issued drug R&D related
   policies in recent years to further enhance approval work requirements of new drugs for marketing, thus bringing certain
   risks for new drug R&D of the Company. Meanwhile, promotion of drugs after marketing is affected by national regulations,
   industry policies, market environment and competitive intensity, causing that income obtained after marketing of new drugs
   cannot reach the expected income, making the Company at risk of product R&D.

   Response measures: The Company will further improve the R&D and innovation systems, introduce and develop high-end
   talents, proactively carry out cooperation and introduction of overseas innovative medicines, strengthen market research and
   evaluation of varieties, reinforce the process regulation and risk management of the initiation of R&D projects, and concentrate
   efforts and make key breakthroughs in the R&D of core products. At the same time, the Group's advantages in APIs will be
   fully utilized to reinforce the integration of API and drug preparations to ensure the long-term sustainable development of the
   Company.

6. Risk of the normalization of COVID-19 pandemic

   In early 2020, the outbreak of the COVID-19 pandemic brought certain impact on the production and operations of the
   Company. As the demand for prescription medicines irrelevant to the pandemic dropped due to the decline of outpatients
   and inpatients in medical institutions, the sales of some products were lower than expected. In the first half of 2021, China
   implemented pandemic prevention and control on a continuing basis and promoted vaccination against the virus in an orderly
   manner. According to data on the ocial website of the National Health Commission, as of 31 December 2021, 31 provinces
   (autonomous regions and municipalities) and Xinjiang Production and Construction Commission had reported a total of
   2,823.42 million doses of vaccines vaccinated, with a full vaccination coverage rate over 85%. However, the emergence of
   new COVID-19 variants has made epidemic prevention and control more complicated, especially since its discovery in South
   Africa in November 2021, Omicron variant has spread widely worldwide. In late January 2022, the outbreak began in Hong
   Kong, China with an average daily new infections exceeded 10,000 in early March. Many parts of Mainland China also report
   a formidable outbreak.

   Response measures: The Company during the Reporting Period was under normal operation, and the overall impact of the
   COVID-19 pandemic on its business was relatively slight. The extent of its subsequent impact will depend on the prevention
   and control of the pandemic on a global scale, the time of continuation, the prevention and control of the pandemic, and the
   responsive measures of enterprises. The Company will continue to pay attention to the development of the pandemic and any
   possible impact on the financial conditions and operating results of the Company, while adopting various measures at the
   same time to mitigate the adverse effect of the pandemic on corporate operations, to ensure that the production and operation
   activities are performed in a steady and orderly manner. Measures include improving operational management, controlling
   various operational risks, and promoting innovation and collaboration. In the face of the new global market pattern brought
   out by COVID-19, the Company will strengthen the export advantages of featured APIs, set up an Internet operation center,
   strengthen online promotion of some preparations, and accelerate the overseas clinical progress of COVID-19 vaccine, so as to
   contribute to the global supply of COVID-19 vaccines and actively fulll its social responsibilities.


(V) Others
   □ Applicable √ N/A


VII Information not disclosed according to guidelines due to inapplicability of the standard,
    involving state secrets or trade secrets or other reasons, and notes on relevant reasons
   □ Applicable √ N/A




                                                                                                                                59
     Chapter 4
     Corporate Governance


 I Corporate Governance
     √ Applicable □ N/A


     During the Reporting Period, the Company continued to improve its corporate governance structure, strengthen information
     disclosure management, enhance investor relations management and internal control to standardize the operation of the
     Company in strict accordance with the laws and regulations, including the Company Law, the Securities Law, the Guidelines
     for Corporate Governance of Listed Companies, and the Rules Governing the Listing of Stocks on Shanghai Stock Exchange.

 1. Shareholders and General Meetings
     During the Reporting Period, 1 annual general meeting and 5 extraordinary general meetings were held by the Company. The
     Company convened and held general meetings in strict compliance with the Articles of Association, Rules of Procedure for
     General Meetings and other relevant regulations to ensure that resolutions can be made at general meetings based on fairness
     and openness, thereby safeguarding the rights and interests of shareholders. In addition, the Company made full use of modern
     information technology such as online voting to ensure that all shareholders, particularly minority shareholders, can attend
     general meetings and exercise their rights to know and participate in decision making in the most convenient and fastest way.

 2. Controlling shareholders and the listed company
     The Company is able to carry on its business and operations independently. In terms of business, personnel, assets,
     organizations and finance, the Company performed management and accounting independently from the controlling
     shareholders of the Company. The controlling shareholders of the Company have exercised their rights and assumed their
     obligations in strict compliance with the laws and regulations, and have never directly or indirectly interfered with the
     decision-making or business activities of the Company without authorization of the general meeting. The Company has
     formulated the Management Policy of Joincare Pharmaceutical Group Industry Co., Ltd. for Preventing the Controlling
     Shareholders or De Facto Controller and Other Related Parties from Using Funds of the Company, and established a long-term
     mechanism to prevent the controlling shareholders or de facto controller and their related parties from using funds of the listed
     company or damaging the interests of the listed company. During the Reporting Period, there was no circumstance where the
     Company's controlling shareholders, de facto controller, and their related parties occupied assets of the Company or damaged
     the interests of the Company and minority shareholders.

 3. Directors and the Board
     During the Reporting Period, the Company held 23 board meetings in multiple ways, including on-the-spot meeting,
     attendance through electronic means and the combination of on-the-spot meeting and electronic means, providing convenience
     for the attending directors. During the Reporting Period, the Board of the Company performed its duties actively and
     eectively in strict compliance with the relevant regulations, including the Company Law, the Articles of Association, and the
     Rules of Procedure for Board Meetings.

     The Board of the Company comprises a total of 9 directors, including 4 independent directors who are legal and financial
     professionals and provide constructive advice for the effective, standard governance and decision-making on major policies
     of the Company. Besides, five special committees are set up under the Board of the Company, namely the Audit Committee,
     the Remuneration Committee, the Strategy Committee, the Nomination Committee, and the Corporate Social Responsibility
     Committee. These committees assist the Board in performing its decision-making and supervision functions and give full play
     to their expertise, so as to ensure the legality, scienticity, and correctness of decisions made by the Board.

     During the Reporting Period, the Company convened, held and voted at the board meetings in accordance with the Rules of
     Procedure for Board Meetings, and all directors of the Company have attended meetings including the board meeting and general
     meeting in a conscientious, responsible and honest manner, actively participated in relevant business training, familiarized
     themselves with relevant laws and regulations, and claried the rights, obligations and responsibilities of directors.


60
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                                                                                                                      2021


4. Supervisors and the Supervisory Committee
   During the Reporting Period, the Company held 15 meetings of the Supervisory Committee for review of the periodic report,
   option exercise, special report on fund raising, and other matters of the Company. The Supervisory Committee of the Company
   is comprised of three supervisors, including one employee's representative. During the Reporting Period, the Supervisory
   Committee of the Company performed its duties in accordance with the law, supervised the duty performance of directors and
   senior management of the Company, carried out regular inspections on the nancial position of the Company, and focused on
   signicant investments of the Company, fully protecting the interests of the Company and all shareholders.

5. Performance evaluation and incentive restraint mechanism for senior management
   The appointment and dismissal of and reward and punishment for senior management of the Company are performed in strict
   accordance with the relevant laws, regulations, and the Articles of Association. The Company has established the selection,
   appointment and performance assessment criteria and the remuneration decision-making procedure for the senior management.
   The Nomination Committee of the Company provided appropriate candidates for directors and senior management in
   accordance with the law, and submitted the list of candidates to the Board of the Company for review. The Remuneration
   Committee of the Company, pursuant to the regulations such as the Management Policy on the Remuneration and Performance
   Assessment of Senior Management, determined the result of performance assessment of senior management based on the
   completion of business objectives of the Company and work objectives of the senior management in 2021. Based on the result
   of performance assessment, the performance bonus and remuneration of senior management in 2021 were determined and
   submitted to the Board of the Company for review and resolution.

6. Investor relations
   The Company has always attached great importance to communication and exchange with investors. The Board designated
   departments and personnel to manage information disclosure and investor relations, enhance communication with minority
   shareholders, answer questions from shareholders on the production, management and operation of the Company, and listen
   earnestly to the suggestions and advice of shareholders on the strategy and development of the Company. Without violating
   regulations, the Company satisfied to the maximum extent the information needs of investors for the sustainable and healthy
   development of the Company.

7. Information disclosure and transparency
   The Company disclosed information in a timely, accurate, authentic and complete manner in strict compliance with the
   relevant regulations, including the Company Law, the Rules Governing the Listing of Stocks on Shanghai Stock Exchange, the
   Articles of Association, and the Information Disclosure Management Bylaws. The Company designated the Board Secretary
   to manage information disclosure, receive visitors, answer questions consulted, contact shareholders, and provide investors
   with the information publicly disclosed by the Company. The Company has the ability to disclose information in an authentic,
   accurate, complete and timely manner in accordance with the laws, regulations, and the Articles of Association, and is able to
   ensure equal access to information for all shareholders.




                                                                                                                              61
 8. Stakeholders
     The Company has fully respected the legitimate rights and interests of stakeholders, including banks, other creditors,
     employees, consumers, suppliers and communities, and has extended communication and cooperation with such stakeholders
     based on mutual benefit, so as to jointly promote the sustained and healthy development of the Company and protect the
     interests of public shareholders.

     During the Reporting Period, the Company did not provide undisclosed information to its substantial shareholders or de facto
     controller, and the substantial shareholders and de facto controller of the Company did not interfere with the production,
     operation and management of the listed company. Overall, no corporate governance irregularities were found.

     The corporate governance of the Company complies with the Company Law and relevant regulations issued by the CSRC.
     Achieving good corporate governance is a long journey, which requires continuous improvement. The Company will
     continue to timely update and improve its internal governance system in accordance with relevant regulations, discover and
     solve problems in a timely manner, and strengthen internal management, so as to promote standard operation and corporate
     governance and advance the steady and healthy development of the Company.

 9. Establishment and implementation of insider registration management system for inside information
     The Resolution relating to Amendment of the Insider Registration Management System for Inside Information of Joincare
     Pharmaceutical Group Industry Co., Ltd. was revised and approved at the 8th meeting of the 8th session of the Board of the
     Company, with a view to strengthening the confidentiality of inside information, maintaining the principles of openness,
     fairness and justice for the Company's information disclosure, and protecting the legitimate rights and interests of investors.
     During the Reporting Period, the Board Office of the Company was responsible for the management of inside information of
     the Company. It is stipulated that the documents and data reported and transmitted externally and other information involving
     inside information and information disclosure shall be reviewed and approved by the Board or the Board Secretary. When
     preparing periodic reports and planning significant matters, the Company performed inside information registration timely,
     and reminded the insiders by mail or phone not to deal with shares of the Company during the sensitive period. Through self-
     inspection, it was found that there was no circumstance where the insiders dealt with shares and derivatives using inside
     information of the Company during the Reporting Period.

     Whether there are any material deviations of the Company's corporate governance from laws, administrative regulations and
     CSRC regulations on the governance of listed companies; If any, give the reasons.
     □ Applicable √ N/A


 II Measures taken by the controlling shareholder and de facto controllers to ensure the
    independence of the Company's assets, personnel, finance, organization, business, in
    addition to solutions, work schedules and follow-up work plans adopted to enhance the
    independence of the Company
     □ Applicable √ N/A

     Engagement in the same or similar business as the Company by controlling shareholders, de facto controllers and other units
     under their control, and the influence of horizontal competition or major changes in horizontal competition on the Company,
     countermeasures taken, progress and follow-up plan
     □ Applicable √ N/A




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                                                                                                                            2021


III Introduction to General Meetings

                               Query index of the
   Meeting       Date of       designated website Disclosure
                                                                                          Meeting resolution
   session       meeting       for publishing the date
                               resolution
                                                               The Resolution on Repurchase of Shares of the Company through
   2021 First                                                  Centralized Bidding Transactions and the Resolution on the General
                                                  26
   Extraordinary 25 February                                   Meeting for Granting Mandate to Deal with Matters Regarding the
                               www.sse.com.cn     February
   General       2021                                          Repurchase were considered and approved. See the Announcement on
                                                  2021
   Meeting                                                     Resolutions of Joincare Pharmaceutical Group Industry Co., Ltd. at the
                                                               2021 First Extraordinary General Meeting (Lin 2021-025) for details.
                                                               Thirteen (13) resolutions were considered and approved, including the
                                                               2020 Annual Work Report of the Supervisory Committee, 2020 Annual
   2020 Annual                                                 Work Report of the Board of Directors, 2020 Annual Prot Distribution
                                                  22 May
   General       21 May 2021 www.sse.com.cn                    Scheme, and 2020 Annual Report of Joincare Pharmaceutical Group
                                                  2021
   Meeting                                                     Industry Co., Ltd. (Full Text and Abstract). See the Announcement on
                                                               Resolutions of Joincare Pharmaceutical Group Industry Co., Ltd. at the
                                                               2020 Annual General Meeting (Lin 2021-063) for details.
                                                               Five (5) resolutions were considered and approved, including the
                                                               Resolution on Increase of Ways for Investments of Projects Invested
   2021 Second
                                                               with Proceeds and the Resolution on the First Phase Ownership Scheme
   Extraordinary                                  30 June
                 29 June 2021 www.sse.com.cn                   under Medium to Long-term Business Partner Share Ownership Scheme
   General                                        2021
                                                               of the Company (Draft) and its Summary. See the Announcement on
   Meeting
                                                               Resolutions of Joincare Pharmaceutical Group Industry Co., Ltd. at the
                                                               2021 Second Extraordinary General Meeting (Lin 2021-081) for details.
                                                               Seven (7) resolutions were considered and approved, including the
                                                               Resolution on Increase of Board Seats and Amendment to Certain
   2021 Third                                                  Clauses of the Articles of Association, the Resolution on Adjustment
   Extraordinary 27 August                        28 August    to Emoluments of Independent Directors of the Company, and the
                               www.sse.com.cn
   General       2021                             2021         Resolution on Modication of Certain Clauses of the Work System for
   Meeting                                                     Independent Directors. See the Announcement on Resolutions of Joincare
                                                               Pharmaceutical Group Industry Co., Ltd. at the 2021 Third Extraordinary
                                                               General Meeting (Lin 2021-111) for details.
                                                           Four (4) resolutions were considered and approved, including the
                                                           Resolution in Relation to Providing a Three-Year Financing Guarantee
   2021 Fourth                                             for the Controlling Subsidiary Livzon MAB by Livzon Group and the
                                                  13
   Extraordinary 12 November                               Counter Guarantee for Livzon Group by the Company, and the Resolution
                             www.sse.com.cn       November
   General       2021                                      in Relation to Amendment of the Business Scope of the Company. See
                                                  2021
   Meeting                                                 the Announcement on Resolutions of Joincare Pharmaceutical Group
                                                           Industry Co., Ltd. at the 2021 Fourth Extraordinary General Meeting (Lin
                                                           2021-133) for details.
                                                           The Resolution on Repurchase of Shares of the Company through
   2021 Fifth                                              Centralized Bidding Transactions and the Resolution on the General
                                                  24
   Extraordinary 23 December                               Meeting for Granting Mandate to Deal with Matters Regarding the
                             www.sse.com.cn       December
   General       2021                                      Repurchase were considered and approved. See the Announcement on
                                                  2021
   Meeting                                                 Resolutions of Joincare Pharmaceutical Group Industry Co., Ltd. at the
                                                           2021 Fifth Extraordinary General Meeting (Lin 2021-154) for details.




                                                                                                                                        63
     Holders of preferred shares with restored voting rights requesting to hold extraordinary general meeting
     □ Applicable √ N/A

     Explanations to general meetings
     □ Applicable √ N/A


IV Information on directors, supervisors and senior management

 (I) Changes in shareholding and remuneration of current directors, supervisors, and senior management and those left
     the Company during the Reporting Period
     √ Applicable □ N/A
                                                                                                                                                            Unit: shares
                                                                                                                                          Total pre-tax     Receive any
                                                                              Number                                                      remuneration      remuneration
                                                                                          Number of
                                                    Start date   End date    of shares                                                  received from the     from any
                                                                                          shares held   Change in       Reason for
     Name           Position (Note)    Gender Age   of the       of the     held at the                                                 Company during         related
                                                                                           at the end shareholding       change
                                                    oce term oce term       beginning                                                    the Reporting       party of the
                                                                                          of the year
                                                                            of the year                                                      Period         Company or
                                                                                                                                         (Ten thousand)          not
                                                    28 August 27 August
     Zhu Baoguo     Chairman           Male   60                                                                                              339.56             No
                                                    2021      2024
                                                    28 August 27 August
     Liu Guangxia   Vice Chairman      Female 53                                                                                              359.27             No
                                                    2021      2024
                    Director,                       28 August 27 August
     Yu Xiong                          Male   61                              430,000        660,000      230,000 Equity incentive            335.00             No
                    President                       2021         2024
                    Director, Vice
                                                    28 August 27 August
     Qiu Qingfeng   President, Chief   Male   51                              357,409       537,409       180,000 Equity incentive            173.62             Yes
                                                    2021         2024
                    Financial Ocer
                    Director, Vice                  28 August 27 August
     Lin Nanqi                         Male   40                              811,040      1,051,040      240,000 Equity incentive            173.62             No
                    President                       2021      2024
                    Independent                     28 August 27 August
     Cui Liguo                         Male   52                                                                                               10.00             No
                    Director                        2021      2024
                    Independent                     28 August 27 August
     Huo Jing                          Female 46                                                                                               10.00             No
                    Director                        2021      2024
                    Independent                     28 August 27 August
     Qin Yezhi                         Male   48                                                                                               10.00             No
                    Director                        2021      2024
                    Independent                     28 August 27 August
     Peng Juan                         Female 58                                                                                                3.60             No
                    Director                        2021         2024
                    Chairman of
                                                    28 August 27 August
     Yu Xiaoyun     the Supervisory    Male   54                                                                                               68.29             No
                                                    2021         2024
                    Committee
                                                    28 August 27 August
     Peng Jinhua    Supervisor         Female 60                               38,043         38,043            0                              38.09             No
                                                    2021      2024
                                                    28 August 27 August
     Xie Youguo     Supervisor         Male   65                               75,442         75,442            0                              44.38             No
                                                    2021         2024
                                                                                                                     Equity incentive
                    Vice President,
     Zhao                                           28 August 27 August                                                and purchase
                    Secretary to the   Male   47                              407,400        588,000      180,600                             168.62             No
     Fengguang                                      2021         2024                                                    from the
                    Board
                                                                                                                     secondary market
     Total          /                  /      /     /            /          2,119,334      2,949,934      830,600           /               1,734.05              /
     Note: Mr. Zhu Baoguo serves as the chairman of Livzon Group, a controlled subsidiary of the Company; and Mr. Yu Xiong
     and Mr. Qiu Qingfeng serve as non-executive directors of Livzon Group. The remuneration listed above does not include the
     part paid by Livzon Group. Please refer to Livzon Group's 2021 Annual Report for details.

64
                                                                                                          Annual Report
                                                                                                                  2021


Name                                                      Main work experience
               Male, born in 1962, with a bachelor's degree. He was the director of Henan Xinxiang Waterborne Resin
               Research Institute, vice chairman and general manager of Henan Feilong Fine Chemical Products Co.,
               Ltd., and had been the general manager and vice chairman of the Company since 1992. He is currently the
Zhu Baoguo
               chairman of the Company and the chairman of Livzon Pharmaceutical Group Inc. Mr. Zhu Baoguo is a
               shareholder of Shenzhen Baiyeyuan Investment Co., Ltd., a controlling shareholder of the Company, and is
               the de facto controller of the Company.
             Female, born in 1969, with a college degree. She was the manager of the Advertising Department of CCTV
             International Corporation Shenzhen, deputy general manager and director of the Company, and the vice
Liu Guangxia chairman of Livzon Group. She is currently the vice chairman of the Company. Ms. Liu Guangxia is a
             shareholder of Shenzhen Baiyeyuan Investment Co., Ltd., a controlling shareholder of the Company, and is
             the spouse of Mr. Zhu Baoguo, the de facto controller of the Company.
               Male, born in 1961, researcher. He graduated from the Department of Chemistry of Fudan University with
               a bachelor of science degree in July 1984. In 1999, he received the special government allowance from the
               State Council. In 2004, he studied at KU Leuven in Modern Enterprise Management. From July 2005 to
               January 2006, he worked as a senior visiting scholar at California State University, Northridge. Since 2016,
               he had been the vice president of the Company. He serves currently as director and president of the Company,
               director of Livzon Group, chairman of Shanghai Frontier and Haibin Pharma, independent director of Tianjin
               Tianyao Pharmaceuticals Co., Ltd. and Sichuan Biokin Pharmaceutical Co., Ltd., director of Shanghai Huatai
               Investment Development Co., Ltd., honorary director of Chinese Pharmaceutical Association, honorary
Yu Xiong       chairman of Pharmaceutical Engineering Specialized Committee, honorary director of Shanghai Society of
               Chemistry and Chemical Industry, and adjunct professor of East China University of Science and Technology.
               He was formerly the vice president of China State Institute of Pharmaceutical Industry, chemistry department
               director and vice president of Shanghai Institute of Pharmaceutical Industry, chairman of Shanghai Techwell
               Biopharmaceutical Co., Ltd., legal person of National Shanghai Center for New Drug Safety Evaluation and
               Research, and general manager and chairman of Sinopharm Yangzhou VAC Biological Engineering Co.,
               Ltd. He was also the person in charge of the comprehensive new drug research and development platform
               under the national key project of“new drug creation”(Shanghai Institute of Pharmaceutical Industry) and the
               technical chief of rolling projects under the 12th Five-Year Plan.
             Male, born in 1971, with an executive master of business administration degree from China Europe
             International Business School, member of Chinese Institute of Certied Public Accountants (non-practicing).
             He worked at Tianjin No.1 Machine Tool Works. Since 1996, he had served successively as the finance
Qiu Qingfeng
             personnel, finance supervisor, finance manager, deputy general manager of the Company, and the general
             manager, board secretary, and president of the Company. He is currently the director, vice president and chief
             nancial ocer of the Company and a non-executive director of Livzon Pharmaceutical Group Inc.
               Male, born in 1982, with a bachelor of engineering degree. He was formerly the workshop supervisor
               of Chongqing Daxin Pharmaceutical Co., Ltd., the workshop manager, production director and
Lin Nanqi      deputy general manager of Livzon Group Xinbeijiang Pharmaceutical Manufacturing Inc., and the
               general manager of Jiaozuo Joincare Bio Technological Co., Ltd., a wholly-owned subsidiary of the
               Company. He is currently the director and vice president of the Company.
               Male, born in 1970, with a master of laws degree. He is the founding partner and director of Management
               Committee of Beijing Guantao Law Firm. He is currently an independent director of the Company, APT
Cui Liguo      Satellite Holdings Limited (security code: 01045), CNNC International Ltd. (security code: 02302), Frontier
               Services Group Ltd. (security code: 00500), China Coal Xinji Energy Co., Ltd. (security code: 601918),
               Essence Securities Co., Ltd. and Beijing Life Insurance Co., Ltd.




                                                                                                                          65
     Name                                                       Main work experience
                   Female, born in 1976, with a bachelor's degree. She is a member of All China Lawyers Association and
                   Tencent Guangdong Real Estate Think Tank. She was a specially invited lawyer by chinacourt.org, 9ask.
                   cn, 66law.cn, Southern Metropolis Daily, and Shenzhen Evening News. Since 2007, she has been the lawyer
                   and partner of Guangdong Sun Law Firm. She was a member of Real Estate Specialized Committee of
     Huo Jing
                   Shenzhen Lawyers Association, and served successively as permanent legal adviser to many companies, fully
                   responsible for the review of corporate legal affairs, drafting and amendment of economic contracts, and
                   issuance of legal opinions, with extensive litigation experience for various types of cases. She is currently an
                   independent director of the Company.
                   Male, born in 1974, with a bachelor's degree, a practicing member of Chinese Institute of Certified Public
                   Accountants and China Certified Tax Agents Association, and a non-practicing member of China Certified
                   Public Valuers Association. He successively served as auditor of Shenzhen Zhengfeng Lifu Accounting Firm,
     Qin Yezhi
                   partner of Shenzhen Jinzheng Accounting Firm, and partner of Asia Pacific (Group) CPAs (Special General
                   Partnership). From 2014 to date, he has served as partner of China Shu Lun Pan Certied Public Accountants
                   LLP. He is currently an independent director of the Company.
                   Female, born in 1964, doctor and doctoral supervisor. From 1997 to date, she has been an associate
                   professor at the Department of Accounting of Antai College of Economics and Management in Shanghai
                   Jiao Tong University, covering research areas of digital finance, green finance, marketing audit, and
                   corporate governance. She is currently an independent director of the Company.She successively served as
                   instructor at the Department of Accounting of School of Economics and Management in Shanghai Maritime
                   University, and director of Executive Education Center of Antai College of Economics and Management
                   in Shanghai Jiao Tong University. She is currently the president and training supervisor of Shanghai Cost
     Peng Juan
                   Research Society of Shanghai Jiao Tong University, adviser of China Financial Cloud Institute, a member
                   of Behavioral Science Council, China marketing certification training specialist, a member of Finance
                   and Accounting Association of Shanghai Jiao Tong University, and a member of Green Finance Center of
                   Shanghai Environment and Energy Exchange. She served concurrently as independent director of Zhejiang
                   Dibay Electric Co., Ltd. (security code: 603320), Kexin Development Co., Ltd., Shanxi (security code:
                   600234), Dynamiker Biotechnology (Tianjin) Co., Ltd. and Jiangsu Pizhou Rural Commercial Bank, and
                   supervisor of Shanghai Jiaopeng Technology Co., Ltd.
                   Male, born in 1968, with a bachelor's degree, and an MBA degree from University of Greenwich. He is a
                   senior engineer and high-level professional talent of Shenzhen. He worked for Henan Institute of Traditional
                   Chinese Medicine. From December 1992 to date, he has served successively as technical manager of the
     Yu Xiaoyun
                   Company, government affairs manager of Institute of Traditional Chinese Medicine, and vice president of
                   the Institute. He is currently the adviser of the Institute and chairman of the Supervisory Committee of the
                   Company, and also a standing member of China Healthcare Association.
                   Female, born in 1962, with a college degree. She served as technical data processor at State-owned 272nd
                   Plant of Ministry of Nuclear Industry and accountant of the staff hospital of the Plant, teacher of Hengyang
                   Radio & TV University, and finance manager of Shenzhen New Era Industrial City Industrial Co., Ltd. She
     Peng Jinhua
                   joined the Company in March 1994, and served successively as nance supervisor, manager of planning and
                   nance department, manager of nance department, manager of tax department, administration manager, and
                   general manager assistant. She is currently a supervisor of the Company.
                   Male, born in 1957, with a bachelor's degree. Since 2003, he served successively as pharmaceutical factory
                   director of the Company's wholly-owned subsidiary Shenzhen Taitai Pharmaceutical Co., Ltd., executive
     Xie Youguo    deputy general manager and general manager of the Company's wholly-owned subsidiary Shenzhen Haibin
                   Pharmaceutical Co., Ltd. He is currently an inspector of Shenzhen Haibin Pharmaceutical Co., Ltd. and a
                   supervisor of the Company.




66
                                                                                                               Annual Report
                                                                                                                       2021


    Name                                                       Main work experience
                    Male, born in 1975, with a bachelor of economics degree and master of science degree, member of Jiusan
                    Society. He was formerly the secretary to president of Shenyang Pharmaceutical University, council secretary
                    and office director of Shenzhen Research Center of Traditional Chinese Medicine and Natural Products,
    Zhao            and assistant to director of Chinese Medicine Laboratory of Research Institute of Tsinghua University in
    Fengguang       Shenzhen. Since August 2011, he served successively as manager of project research and management
                    department of the institute of the Company, deputy head and project research director of the institute of the
                    Group, and director of the controlling subsidiary Shanghai Frontier. He is currently the vice president and
                    board secretary of the Company.


    Explanations of other relevant information
    √ Applicable □ N/A

    On 10 August 2021, the Company convened the 52nd meeting of the seventh session of the Board of Directors, at which the
    Resolution on Addition of Board Seats and Revision of Provisions of the Articles of Association, the Resolution on General
    Election of the Board of Directors and Election of Non-Independent Directors of the 8th Session of the Board of the Company
    and the Resolution on General Election of the Board of Directors and Election of Independent Directors of the 8th Session of
    the Board of the Company were considered and approved; at the same time, the Company convened the 39th meeting of the
    seventh session of the Supervisory Committee, at which, the Resolution on General Election of the Supervisory Committee
    and Election of Supervisors of the 8th Session of the Supervisory Committee of the Company was considered and approved.
   According to the resolution, the number of supervisors of the Company increased from 7 to 9, and the resolution was submitted
   to the annual general meeting for deliberation. On 27 August 2021, the Company convened the 2021 third extraordinary
   general meeting, at which the Resolution on Addition of Board Seats and Revision of Provisions of the Articles of Association,
   the Resolution on General Election of the Board of Directors and Election of Non-Independent Directors of the 8th Session of
   the Board of the Company, the Resolution on General Election of the Board of Directors and Election of Independent Directors
   of the 8th Session of the Board of the Company and the Resolution on General Election of the Supervisory Committee and
   Election of Supervisors of the 8th Session of the Board of the Company were considered and approved. Following the general
   meeting of shareholders on the day, the rst meeting of the 8th session of the Board of Directors was held by the Company, at
   which, the Resolution on Appointment of Senior Management of the 8th Session of the Board of Directors was considered and
   approved. For details, please see the Announcement of Joincare Pharmaceutical Group Industry Co., Ltd. on Completion of the
   General Election of the Board of Directors, the Supervisory Committee and Senior Management disclosed by the Company on
   28 August 2021 (Lin 2021-114).


(II) Posts held by current directors, supervisors, and senior management and those resigned during the Reporting Period
1. Posts held at corporate shareholders of the Company
   √ Applicable □ N/A


                     Corporate
    Name                             Posts held                      Start date of the oce term      End date of the oce term
                     shareholder
    Zhu Baoguo       Baiyeyuan       Chairman, General Manager       11 March 2014                                /
    Liu Guangxia     Baiyeyuan       Director                        21 January 1999                              /
                     Mr. Zhu Baoguo, Chairman of the Company, directly holds 90% of shares in Baiyeyuan, and Ms. Liu Guangxia,
    Note             Vice Chairman of the Company, directly holds 10% of shares in Baiyeyuan. Both of them are directors of
                     Baiyeyuan, and Mr. Zhu Baoguo is the spouse of Ms. Liu Guangxia.




                                                                                                                               67
 2. Posts held at other entities
    √ Applicable □ N/A


                                                                                                      Start date of the   End date of the
     Name                                Other entities                              Posts held
                                                                                                      oce term              oce term
                     Shenzhen Federation of Industry and Commerce         Honorary Vice President     November 2014              /
                     Federation of Shenzhen Commerce                      Director                    April 2015                 /
                     TNC Greater China Council of Advisors                Council Member              December 2012              /
     Zhu Baoguo
                     The Paradise International Foundation                Director                    April 2015                 /
                     China Entrepreneur Club                              Council Member              April 2017                 /
                     Central China Management Company Limited             Independent Director        May 2021
                    Chinese Pharmaceutical Association                    Honorary Director           January 2022               /
                    Shanghai Society of Chemistry and Chemical Industry   Honorary Director           October 2016               /
                    Tianjin Tianyao Pharmaceuticals Co., Ltd.             Independent Director        December 2016              /
     Yu Xiong       Sichuan Biokin Pharmaceutical Co., Ltd.               Independent Director        September 2019             /
                    East China University of Science and Technology       Adjunct Professor           July 2019                  /
                    Pharmaceutical Engineering Specialized Committee of
                                                                          Honorary Chairman           November 2019              /
                    Chinese Pharmaceutical Association
     Qiu Qingfeng Jiaozuo Jinguan Jiahua Electric Power Co., Ltd.         Director                    December 2004
                                                                          Director of Management
                     Beijing Guantao Law Firm                             Committee, Founding         February 1994              /
                                                                          Partner
                                                                          Independent non-executive
                     APT Satellite Holdings Limited                                                   July 2007                  /
                                                                          director
                                                                          Independent non-executive
                    CNNC International Ltd.                                                           November 2008              /
                                                                          director
     Cui Liguo
                                                                          Independent non-executive
                    Frontier Services Group Ltd.                                                      June 2020                  /
                                                                          director
                    China Electronics Information Service Co., Ltd.       External Director           July 2016                  /
                    Essence Securities Co., Ltd.                          Independent Director        December 2016              /
                    Beijing Life Insurance Co., Ltd.                      Independent Director        April 2018                 /
                    CEC Xinze (Beijing) Investment Management Co., Ltd. External Director             May 2018                   /
                    China Coal Xinji Energy Co., Ltd.                     Independent Director        May 2019                   /
     Huo Jing        Guangdong Sun Law Firm                               Lawyer, Partner             June 2007                  /
                     China Shu Lun Pan Certied Public Accountants LLP
                                                                          Partner                     July 2014                  /
                     (Special General Partnership)
     Qin Yezhi
                     Shenzhen Yongpeng CTA Firm (Special General
                                                                          Partner                     September 2013             /
                     Partnership)
                     Antai College of Economics and Management of         Associate Professor of
                                                                                                      September 1997             /
                     Shanghai Jiao Tong University                        Department of Accounting
                    Kexin Development Co., Ltd., Shanxi                   Independent Director        July 2016                  /
     Peng Juan      Zhejiang Dibay Electric Co., Ltd.                     Independent Director        August 2016                /
                    Jiangsu Pizhou Rural Commercial Bank                  Independent Director        September 2016             /
                    Dynamiker Biotechnology (Tianjin) Co., Ltd.           Independent Director        July 2020                  /
                    Shanghai Jiaopeng Technology Co., Ltd.                Supervisor                  July 2019                  /
     Yu Xiaoyun     China Healthcare Association                          Executive Council Member June 2015                     /
     Explanations    Not applicable




68
                                                                                                            Annual Report
                                                                                                                    2021


(III) Remuneration of directors, supervisors and senior management
    √ Applicable □ N/A


                                The emolument of chairman and vice chairman of the Company shall follow the Resolutions of
                                the 2018 Second Extraordinary General Meeting of the Company, which is RMB3.25 million
                                per year, with the individual income tax withheld and remitted by the Company in accordance
                                with the relevant regulations of the Tax Law. The emolument of each independent director of
                                the Company, following the Resolutions of the 2021 Third Extraordinary General Meeting of
                                the Company, shall be adjusted to RMB9,000 (before tax) from RMB 8,000 (before tax) per
                                month, with the individual income tax withheld and remitted by the Company in accordance
                                with the relevant regulations of the Tax Law.
                                The emolument of each supervisor of the Company, following the Resolutions of the 2021
                                Third Extraordinary General Meeting of the Company, shall be adjusted to RMB4,000 (before
                                tax) per month from RMB 3,000 (before tax) per month, with the individual income tax
                                withheld and remitted by the Company in accordance with the relevant regulations of the Tax
                                Law. During the Reporting Period, the remuneration received by supervisors is the duty wage
                                based on the Wage System of the Company plus the emolument. During the Reporting Period,
                                the person who acted as the supervisor of the Company received remuneration according to the
                                salary system in addition to the supervisor allowance.
                                The remuneration of senior management of the Company shall follow the resolution of the
                                52nd meeting of the 6th session of the Board of the Company. The annual basic remuneration
                                of the president, vice president and other senior management members during the term of
                                office is RMB2.60 million, RMB1.35 million and RMB1.20 million, respectively. In addition
     Decision-making procedure
                                to the basic remuneration, pursuant to the remuneration management system of the Company,
     regarding remuneration of
                                individual assessment shall be performed and performance bonuses shall be paid according to
     directors, supervisors and
                                the assessment result. In case of holding concurrent positions, the highest remuneration among
     senior management
                                all positions shall prevail.
                                For the Company's directors who serve concurrently as a senior management member of the
                                Company, the remuneration received by them is equal to the wage paid according to their
                                position as a senior management member, and no directors’emoluments are paid by the
                                Company.
                                On 24 January 2022, the Remuneration Committee under the Board of the Company convened
                                the 4th meeting of the 8th session of the Board, at which the Resolution on the 2021 Annual
                                Performance Assessment Result and Remuneration Distribution of Senior Management of
                                the Company was considered and approved. It was agreed that the Company, pursuant to the
                                regulations such as the Management Policy on the Remuneration and Performance Assessment
                                of Senior Management, determined the 2021 annual performance assessment result and annual
                                remuneration of senior management based on the completion of business objectives of the
                                Company and work objectives of the senior management in 2021. On 24 January 2022, the
                                Board of the Company convened the 8th meeting of the 8th session of the Board, at which
                                the Resolution on Remuneration Distribution of Senior Management for the Year 2021 was
                                considered and approved.
                                Except for fulfilling the job responsibilities of being directors, supervisors and senior
                                management of the Company, other remuneration paid for positions held in subsidiaries
                                shall be implemented according to the relevant remuneration system of the corresponding
                                subsidiaries.




                                                                                                                            69
                                      Pursuant to the regulations such as the Management Policy on the Remuneration and
                                      Performance Assessment of Senior Management, the result of performance assessment of
     Basis for determining
                                      senior management is determined based on the completion of business objectives of the
     remuneration of directors,
                                      Company and work objectives of the senior management in 2021. Based on the result of
     supervisors and senior
                                      performance assessment, the performance bonus and remuneration of senior management in
     management
                                      2021 were determined and submitted to be reviewed by the Remuneration Committee under the
                                      Board who shall then submit it to the Board for review and resolution.
     Remuneration actually paid
                                      As at the date of the Report, remuneration of directors, supervisors and senior management has
     to directors, supervisors
                                      been fully paid.
     and senior management
     Total remuneration paid to
     all directors, supervisors
     and senior management as         RMB 17.3405million
     of the end of the Reporting
     Period


(IV) Changes in directors, supervisors and senior management
     √ Applicable □ N/A


     Name                             Position                             Change                      Reason for change
     Yu Xiong                         Director                             Appointed                   Appointed by the Board
     Peng Juan                        Independent Director                 Appointed                   Appointed by the Board


(V) Statement on punishments imposed by securities regulatory authorities in the past three years
     □ Applicable √ N/A


(VI) Others
     □ Applicable √ N/A


 V Board meetings held during the Reporting Period

     Meeting session        Date of meeting                                    Meeting resolution
                                            The Resolution on Equity Transfer and Capital Increase of Zhuhai Livzon
     38th meeting of                        Biotechnology Co., Ltd. was considered and approved. See the Announcement on
     the 7th session        11 January 2021 Resolutions Considered and Approved at the 38th Meeting of the 7th Session of the
     of the Board                           Board of Joincare Pharmaceutical Group Industry Co., Ltd. (Lin 2021-006) disclosed
                                            on 12 January 2021 for details.
                                            The Resolution on Capital Increase of Zhuhai Livzon Biotechnology Co., Ltd. and
     39th meeting of                        the Resolution on Equity Transfer of Livzon MABPharm Inc. were considered and
     the 7th session        18 January 2021 approved. See the Announcement on Resolutions Considered and Approved at the 39th
     of the Board                           Meeting of the 7th Session of the Board of Joincare Pharmaceutical Group Industry
                                            Co., Ltd. (Lin 2021-008) disclosed on 19 January 2021 for details.
                                            The Resolution on Equity Transfer of Livzon Biologics Hong Kong Limited was
     40th meeting of                        considered and approved. See the Announcement on Resolutions Considered
     the 7th session        27 January 2021 and Approved at the 40th Meeting of the 7th Session of the Board of Joincare
     of the Board                           Pharmaceutical Group Industry Co., Ltd. (Lin 2021-011) disclosed on 28 January 2021
                                            for details.




70
                                                                                                      Annual Report
                                                                                                              2021


Meeting session   Date of meeting                                   Meeting resolution
                                  Five (5) resolutions were considered and approved, including the Resolution on
                                  Termination of Matters regarding 2020 Non-public Issuance of Shares of the Company,
41st meeting of
                                  and the Resolution on Repurchase of Shares through Centralized Bidding Transactions.
the 7th session   9 February 2021
                                  See the Announcement on Resolutions Considered and Approved at the 41st Meeting of
of the Board
                                  the 7th Session of the Board of Joincare Pharmaceutical Group Industry Co., Ltd. (Lin
                                  2021-014) disclosed on 10 February 2021 for details.
                                    The Resolution on Repurchase of Shares by Livzon Biologics Limited and the
42nd meeting of                     Resolution on Adjustment of Organizational Structure of the Company were considered
                  25 February
the 7th session                     and approved. See the Announcement on Resolutions Considered and Approved at
                  2021
of the Board                        the 42nd Meeting of the 7th Session of the Board of Joincare Pharmaceutical Group
                                    Industry Co., Ltd. (Lin 2021-022) disclosed on 26 February 2021 for details.
                                    The Resolution on Acquisition of 40% Equity Interest in Tianjin Tongrentang Group
43rd meeting of                     Co., Ltd. by the Controlling Subsidiary Livzon Group was considered and approved.
the 7th session   22 March 2021     See the Announcement on Resolutions Considered and Approved at the 43rd Meeting
of the Board                        of the 7th Session of the Board of Joincare Pharmaceutical Group Industry Co., Ltd.
                                    (Lin 2021-029) disclosed on 23 March 2021 for details.
                                    Eighteen (18) resolutions were considered and approved, including the 2020
                                    Annual Work Report of the President, 2020 Annual Work Report of the Board
44th meeting of                     of Directors, 2020 Annual Profit Distribution Plan, and 2020 Annual Report of
the 7th session   29 March 2021     Joincare Pharmaceutical Group Industry Co., Ltd. (Full Text and Abstract). See the
of the Board                        Announcement on Resolutions Considered and Approved at the 44th Meeting of the 7th
                                    Session of the Board of Joincare Pharmaceutical Group Industry Co., Ltd. (Lin 2021-
                                    033) disclosed on 31 March 2021 for details.
                                    Four (4) resolutions were considered and approved, including the 2021 Q1 Report
                                    of Joincare Pharmaceutical Group Industry Co., Ltd. (Full Text and Body) and the
45th meeting of
                                    Resolution on Change in Registered Capital of the Company. See the Announcement
the 7th session   22 April 2021
                                    on Resolutions Considered and Approved at the 45th Meeting of the 7th Session of the
of the Board
                                    Board of Joincare Pharmaceutical Group Industry Co., Ltd. (Lin 2021-053) disclosed
                                    on 23 April 2021 for details.
                                    The Resolution on Convening the 2020 Annual General Meeting of the Company was
46th meeting of
                                    considered and approved. See the Notice of Joincare Pharmaceutical Group Industry
the 7th session   28 April 2021
                                    Co., Ltd. on Convening the 2020 Annual General Meeting (Lin 2021-057) announced
of the Board
                                    on 29 April 2021 for details.
                                    The Resolution on the Launch of Futures Hedging Activities by Controlling
47th meeting of                     Subsidiaries of Livzon Group was considered and approved. See the Announcement of
the 7th session   7 May 2021        Joincare Pharmaceutical Group Industry Co., Ltd. on the Launch of Futures Hedging
of the Board                        Activities by Controlling Subsidiaries of Livzon Group (Lin 2021-060) disclosed on 8
                                    May 2021 for details.
                                    Six (6) resolutions were considered and approved, including the Resolution on Adding
                                    implementation methods of Usage of Proceeds from Fund-Raising and the Resolution
48th meeting of                     on the First Phase Ownership Scheme under Medium to Long-term Business
the 7th session   10 June 2021      Partner Share Ownership Scheme of the Company (Draft) and its Summary. See the
of the Board                        Announcement on Resolutions Considered and Approved at the 48th Meeting of the 7th
                                    Session of the Board of Joincare Pharmaceutical Group Industry Co., Ltd. (Lin 2021-
                                    068) disclosed on 11 June 2021 for details.




                                                                                                                      71
     Meeting session   Date of meeting                                    Meeting resolution
                                         The Resolution on Adjusting the Exercise Price of the 2018 Share Options Incentive
     49th meeting of                     Scheme of the Company was considered and approved. See the Announcement of
     the 7th session   25 June 2021      Joincare Pharmaceutical Group Industry Co., Ltd. on Adjusting the Exercise Price of
     of the Board                        the 2018 Share Options Incentive Scheme of the Company (Lin 2021-080) disclosed on
                                         26 June 2021 for details.
                                         The Resolution on Changes in Asset Management and Custody Agencies of the
                                         First Phase Ownership Scheme under Medium to Long-term Business Partner Share
     50th meeting of                     Ownership Scheme was considered and approved. See the Announcement of Joincare
     the 7th session   8 July 2021       Pharmaceutical Group Industry Co., Ltd. on Changes in Asset Management and
     of the Board                        Custody Agencies of the First Phase Ownership Scheme under Medium to Long-term
                                         Business Partner Share Ownership Scheme (Lin 2021-085) disclosed on 9 July 2021 for
                                         details.
                                         The Resolution on Conducting Foreign Exchange Derivatives Trading Business was
     51st meeting of
                                         considered and approved. See the Announcement of Joincare Pharmaceutical Group
     the 7th session   29 July 2021
                                         Industry Co., Ltd. on Conducting Foreign Exchange Derivatives Trading Business (Lin
     of the Board
                                         2021-089) disclosed on 30 July 2021 for details.
                                         Seven (7) resolutions were considered and approved, including the Resolution
                                         on Increase of Board Seats and Amendment to Certain Clauses of the Articles of
     52nd meeting of                     Association, and the Resolution relating to Cancellation of Certain Share Options of the
     the 7th session   10 August 2021    Company Granted but Not Yet Exercised under the 2018 Share Option Incentive Plan.
     of the Board                        See the Announcement on Resolutions Considered and Approved at the 52nd Meeting
                                         of the 7th Session of the Board of Joincare Pharmaceutical Group Industry Co., Ltd.
                                         (Lin 2021-095) published on 11 August 2021 for details.
                                         Three (3) resolutions were considered and approved, including the Announcement
                                         of Joincare Pharmaceutical Group Industry Co., Ltd. on Fulfillment of Exercise
     53rd meeting of                     Conditions for the Second Exercise Period of the Reserved Grant under the 2018 Share
     the 7th session   25 August 2021    Options Incentive Scheme of the Company was considered and approved. See the
     of the Board                        Announcement on Resolutions Considered and Approved at the 53rd Meeting of the 7th
                                         Session of the Board of Joincare Pharmaceutical Group Industry Co., Ltd. (Lin 2021-
                                         105) disclosed on 26 August 2021 for details.
                                         Three (3) resolutions were considered and approved, including the Resolution
                                         on Election of Chairman and Vice Chairman of the 8th Session of the Board of
     1st meeting of                      the Company, and the Resolution on Appointment of Senior Management of the
     the 8th session   27 August 2021    8th Session of the Board of the Company. See the Announcement on Resolutions
     of the Board                        Considered and Approved at the 1st Meeting of the 8th Session of the Board of Joincare
                                         Pharmaceutical Group Industry Co., Ltd. (Lin 2021-113) disclosed on 28 August 2021
                                         for details.
                                       The Resolution in Relation to Providing a Credit Line Guarantee for the Wholly-Owned
                                       Subsidiary Shenzhen Haibin Pharmaceutical Co., Ltd. by the Company was considered
     2nd meeting of
                                       and approved. See the Announcement of Joincare Pharmaceutical Group Industry Co.,
     the 8th session   13 October 2021
                                       Ltd. on Providing a Credit Line Guarantee for the Wholly-Owned Subsidiary Shenzhen
     of the Board
                                       Haibin Pharmaceutical Co., Ltd. (Lin 2021-125) disclosed on 14 October 2021 for
                                       details.




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                                                                                                               2021


Meeting session   Date of meeting                                   Meeting resolution
                                  Six (6) resolutions were considered and approved, including the 2021 Q3 Report of
                                  Joincare Pharmaceutical Group Industry Co., Ltd. and the Resolution in Relation to
3rd meeting of                    Providing a Three-Year Financing Guarantee for the Controlling Subsidiary Livzon
the 8th session   26 October 2021 MAB by Livzon Group and the Counter Guarantee for Livzon Group by the Company.
of the Board                      See the Announcement on Resolutions Considered and Approved at the 3rd Meeting of
                                  the 8th Session of the Board of Joincare Pharmaceutical Group Industry Co., Ltd. (Lin
                                  2021-127) disclosed on 27 October 2021 for details.
                                    The Resolution relating to Cancellation of Certain Share Options under the 2018 Share
                                    Option Incentive Plan and the Resolution relating to Adjustment to Projected Daily
4th meeting of                      Connected Transactions of the Controlling Subsidiaries Jiaozuo Joincare and Jinguan
                  15 November
the 8th session                     Electric Power were considered and approved. See the Announcement on Resolutions
                  2021
of the Board                        Considered and Approved at the 4th Meeting of the 8th Session of the Board of
                                    Joincare Pharmaceutical Group Industry Co., Ltd. (Lin 2021-135) disclosed on 16
                                    November 2021 for details.
                                    The Resolution on Fulfillment of Exercise Conditions for the Third Exercise Period of
                                    the First Grant under the 2018 Share Options Incentive Scheme was considered and
5th meeting of
                  29 November       approved. See the Announcement of Joincare Pharmaceutical Group Industry Co.,
the 8th session
                  2021              Ltd. on Fulfillment of Exercise Conditions for the Third Exercise Period of the First
of the Board
                                    Grant under the 2018 Share Options Incentive Scheme of the Company (Lin 2021-140)
                                    disclosed on 30 November 2021 for details.
                                    Three (3) resolutions were considered and approved, including the Resolution on
                                    Repurchase of Shares through Centralized Bidding Transactions and the Resolution
6th meeting of
                  6 December        on the General Meeting for Granting Mandate to Deal with Matters Regarding the
the 8th session
                  2021              Repurchase. See the Announcement on Resolutions Considered and Approved at the
of the Board
                                    6th Meeting of the 8th Session of the Board of Joincare Pharmaceutical Group Industry
                                    Co., Ltd. (Lin 2021-144) disclosed on 7 December 2021 for details.
                                    The Resolution on the Temporary Replenishment of Working Capital with Idle
                                    Proceeds and the Resolution on Appointment of Representative of Securities Aairs of
7th meeting of
                  30 December       the Company were considered and approved. See the Announcement on Resolutions
the 8th session
                  2021              Considered and Approved at the 7th Meeting of the 8th Session of the Board of
of the Board
                                    Joincare Pharmaceutical Group Industry Co., Ltd. (Lin 2021-158) disclosed on 31
                                    December 2021 for details.




                                                                                                                       73
VI Performance of duties by directors

 (1) Attendance by directors of the Board meetings and general meetings

                                                                                                                Attendance of
                                                         Attendance of the Board meetings
                                                                                                               general meetings
                                                                                               Whether the
                       Whether       Meetings              Meetings
                                                                                               director has
     Name            independent    the director Meetings attended          Meetings Absence
                                                                                               been absent
                       director    should have attended     through         attended (times)                 Meetings attended
                                                                                                from two
                                   attended this in person electronic       by proxy
                                                                                               consecutive
                                        year                 means
                                                                                                meetings
     Zhu Baoguo             No          23          23            22            0          0            No             5
     Liu Guangxia           No          23          23            22            0          0            No             1
     Yu Xiong               No             7         7            7             0          0            No             2
     Qiu Qingfeng           No          23          23            22            0          0            No             6
     Lin Nanqi              No          23          23            22            0          0            No             5
     Cui Liguo              Yes         23          23            22            0          0            No             6
     Huo Jing               Yes         23          23            22            0          0            No             6
     Qin Yezhi              Yes         23          23            22            0          0            No             6
     Peng Juan              Yes            7         7            7             0          0            No             2


     Statement on absence from two consecutive meetings
     □ Applicable √ N/A


     Board meetings held during the year                                                                              23
     In which: Face-to-face meetings                                                                                   1
     Meetings held through electronic means                                                                           22
     Meetings held both in the form of face-to-face meeting and through electronic means                               0


 (2) Objections raised by directors to affairs of the Company
     □ Applicable √ N/A

 (3) Others
     □ Applicable √ N/A


VII Board committees
     √ Applicable □ N/A

 (1) Members of the Board committees

     Committee name                                                    Member
     Audit Committee                                                   Qin Yezhi, Huo Jing, Peng Juan
     Nomination Committee                                              Cui Liguo, Qiu Qingfeng, Huo Jing
     Remuneration Committee                                            Huo Jing, Qin Yezhi, Peng Juan
     Strategy Committee                                                Zhu Baoguo, Yu Xiong, Qin Yezhi, Cui Liguo, Peng Juan
     Corporate Social Responsibility (CSR) Committee                   Zhu Baoguo, Lin Nanqi, Cui Liguo




74
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                                                                                                                    2021


(2) 6 meetings were held by the Audit Committee during the Reporting Period

                                                                                                            Important opinion
    Date of meeting                                           Content
                                                                                                             and suggestion
                        Review of the 2020 Annual Financial Statements of Joincare Pharmaceutical Group
    25 January 2021                                                                                            Approved
                        Industry Co., Ltd. (Unaudited)
                        Review of the Draft Audit Opinions for the 2020 Annual Financial Statements of
                                                                                                               Approved
                        Joincare Pharmaceutical Group Industry Co., Ltd.
    22 March 2021
                        Review of the Draft Audit Opinions for the 2020 Annual Internal Control of
                                                                                                               Approved
                        Joincare Pharmaceutical Group Industry Co., Ltd.
                        Review of the Audit Report for the 2020 Annual Financial Statements of the
                                                                                                               Approved
                        Company (Final)
                        Review of the Audit Report for the 2020 Annual Internal Control of the Company
                                                                                                               Approved
                        (Final)
                        Review of the Summary Report on Audit Work for the Year 2020 from Grant
                                                                                                               Approved
                        Thornton (Special General Partnership)
    29 March 2021       Review of the Self-Assessment Report of Joincare Pharmaceutical Group Industry
                                                                                                               Approved
                        Co., Ltd. on Risk Management and Internal Control for the Year 2020
                        Review of the Resolution on Appointment of Grant Thornton (Special General
                                                                                                               Approved
                        Partnership) as the Auditor of the Company for the Year 2021
                        Review of the Resolution on Daily Connected Transactions of the Controlling
                                                                                                               Approved
                        Subsidiaries Jiaozuo Joincare and Jinguan Electric Power
                        Review of the Resolution on Change of Accounting Policies                              Approved
                        Review of the Resolution on Election of Chairman of the Audit Committee under
    27 August 2021                                                                                             Approved
                        the 8th Session of the Board of the Company
                     Review of Resolution relating to Adjustment to Projected Daily Connected
    15 November 2021 Transactions of the Controlling Subsidiaries Jiaozuo Joincare and Jinguan Electric        Approved
                     Power
                        Review of the 2021 Financial Statements and Internal Control Audit Proposal of
    3 December 2021                                                                                            Approved
                        Joincare Pharmaceutical Group Industry Co., Ltd.


(3) 6 meetings were held by the Remuneration Committee during the Reporting Period

                                                                                                            Important opinion
    Date of meeting                                           Content
                                                                                                             and suggestion
                        Review of the Resolution on 2020 Annual Remuneration of Senior Management of
    29 March 2021                                                                                              Approved
                        the Company
                        Review of the Resolution relating to Cancellation of Certain Share Options of the
    10 August 2021      Company Granted but Not Yet Exercised under the 2018 Share Option Incentive            Approved
                        Plan
                        Review of the Resolution on Fulllment of Exercise Conditions for the Second
    25 August 2021      Exercise Period of the Reserved Grant under the 2018 Share Options Incentive           Approved
                        Scheme
                        Review of the Resolution on Election of Chairman of the Remuneration Committee
    27 August 2021                                                                                             Approved
                        under the 8th Session of the Board of the Company
                        Review of the Resolution relating to Cancellation of Certain Share Options under
    15 November 2021                                                                                           Approved
                        the 2018 Share Option Incentive Plan
                        Review of the Resolution on Fulllment of Exercise Conditions for the Third
    29 November 2021                                                                                           Approved
                        Exercise Period of the First Grant under the 2018 Share Options Incentive Scheme



                                                                                                                           75
 (4) 2 meetings were held by the Nomination Committee during the Reporting Period

                                                                                                                Important opinion
      Date of meeting                                           Content
                                                                                                                 and suggestion
                          Review of the Resolution on General Election of the Board of Directors and Election
      7 August 2021                                                                                                   Approved
                          of Non-Independent Directors of the 8th Session of the Board of the Company
                          Review of the Resolution on Election of Chairman of the Nomination Committee
      27 August 2021                                                                                                  Approved
                          under the 8th Session of the Board of the Company


 (5) 2 meetings were held by the Strategy Committee during the Reporting Period

                                                                                                                Important opinion
      Date of meeting                                           Content
                                                                                                                 and suggestion
      25 February 2021    Review of the Resolution on Adjustment of Organizational Structure of the Company           Approved
                          Review of the Resolution in Relation to Amendment of the Business Scope of the
      26 October 2021                                                                                                 Approved
                          Company


 (6) 3 meetings were held by the Corporate Responsibility Committee during the Reporting Period

                                                                                                                Important opinion
      Date of meeting                                           Content
                                                                                                                 and suggestion
                          Review of the 2020 Corporate Social Responsibility Report of Joincare
                                                                                                                      Approved
                          Pharmaceutical Group Industry Co., Ltd.
      29 March 2021
                          Review of the Energy Saving and Emission Reduction Targets of Joincare
                                                                                                                      Approved
                          Pharmaceutical Group Industry Co., Ltd. (2021-2025)
                          Review of the Resolution on Election of Chairman of the Corporate Responsibility
      27 August 2021                                                                                                  Approved
                          Committee under the 8th Session of the Board of the Company
                          Review of the Resolution on Establishment of 2021 Corporate Responsibility Work
      15 November 2021                                                                                                Approved
                          Group of Joincare Pharmaceutical Group Industry Co., Ltd.


 (7) Affairs subject to objection
     □ Applicable √ N/A


VIII Statement on risks of the Company identified by the Board of Supervisors
     □ Applicable √ N/A

     The Supervisory Committee had no objection to the matters under their supervision within the reporting period.




76
                                                                                                                 Annual Report
                                                                                                                         2021


IX Employees of the parent company and major subsidiaries

(I) Employees

     Number of active employees of the parent company                                                                          411
     Number of active employees of major subsidiaries                                                                       12,823
     Total number of active employees                                                                                       13,234
     Number of retired employees for whom the parent company and
                                                                                                                               665
     major subsidiaries need to pay certain expenses
                                                              Profession
     Category                                                                                                             Number
     Production sta                                                                                                          7,612
     Sales sta                                                                                                               2,634
     Technical sta                                                                                                           1,980
     Financial sta                                                                                                             262
     Administrative sta                                                                                                        746
     Total                                                                                                                  13,234
                                                        Education background
     Education background                                                                                                 Number
     PhD                                                                                                                        62
     Master                                                                                                                    611
     Undergraduate                                                                                                           3,368
     Junior college diploma                                                                                                  3,569
     Others                                                                                                                  5,624
     Total                                                                                                                  13,234


(II) Compensation policy
    √ Applicable □ N/A

    The Company implements scientic, reasonable and incentive-based compensation strategies. Based on scientic analysis and
    assessment of the organizational structure and job responsibilities, the Company determines the relative value of each position,
    and by combining the external market compensation data and the ability of the Company to pay, the Company provides a
    reasonable employee compensation package. Employee compensation consists of two parts: xed income and variable income.
    Variable income is linked to business results of the Company and individual performance of employees. In this way, employees
    are encouraged to increase their enthusiasm and motivation at work. Competitive compensation policies are adopted for talents
    in key positions and those urgently needed in the market, so as to prevent loss of key talents and provide a talent pool for the
    development of the Company.


(III) Training programs
    √ Applicable □ N/A

    In 2021, the Company continued to attach great importance to internal talent training. With multi-level, diversified training
    systems and a combination of online and offline learning, the Company organized and carried out new employee orientation
    training, employee on-the-job training, career-based study for a master's or doctor's degree, and training team building.
    Meanwhile, the Company encouraged employees to actively participate in external learning activities related to work,
    facilitated the improvement of employee competence and team cohesion, and built talent teams.


(IV) Outsourced workers
    □ Applicable √ N/A



                                                                                                                                 77
 X Profit distribution proposal or proposal for capitalization of capital reserve

 (I) Formulation, implementation or adjustment of cash dividend distribution policy
     √ Applicable □ N/A

 1. Formation of Cash dividend policy

     To establish a scientific, consistent and stable decision-making and supervision mechanism for dividends, and fully protect
     and safeguard the rights and interests of the majority of shareholders, the Company formulated this cash dividend policy
     in accordance with the“Regulatory Guidelines for Listed Companies No. 3 - Distribution of Cash Dividends of Listed
     Companies”released by China Securities Regulatory Commission (CSRC announcement [2022] No. 3) and the“Regulatory
     Guideline for Self-regulation of Listed Companies No. 1 - Standardized Operation”released by Shanghai Stock Exchange and
     other relevant documents and requirements and in light of the reality of the Company, and claried the formulation, decision-
     making and adjustment procedures for the policy in the Articles of Association: If the Company is in a sound operating
     condition and its cash flow can meet the needs of normal operation and long-term development, the Company shall actively
     implement the profit distribution policy to provide reasonable returns to investors while taking into account the sustainable
     development of the Company, in order to maintain the continuity and stability of the policy. The profits may be distributed
     in cash, stocks, or combination thereof or in any other way permitted by laws and regulations. Cash dividends are superior to
     stock dividends in the distribution of prots, and shall be adopted whenever the conditions are met. Unless otherwise provided
     for in the Articles of Association, the profits distributed in cash shall not be less than 10% of the distributable profits realized
     in the current year. The specific amount and proportion of cash dividends for each year shall be determined by the Board of
     Directors of the Company in accordance with relevant provisions and in light of the Company's current operating situation, and
     shall be reported to the annual general meeting for deliberation and decision.

 2. Implementation of cash dividend policy in 2021

     On 21 May 2021, the Company convened the 2020 Annual General Meeting, at which the Company's Prot Distribution Plan
     for 2020 was considered and approved: a cash dividend of RMB 1.50 (tax inclusive) will be distributed to all shareholders
     for every 10 shares, based on the total share capital of the Company on the equity registration date as determined for
     implementation of the Company's prot distribution plan for 2020, minus the total number of shares in the Company's special
     securities account for repurchase, with the remaining undistributed prots to be carried forward to the following year. As of the
     end of this Reporting Period, the above cash dividends have been fully distributed.

 3. Prot distribution scheme for 2021

     Based on the audit conducted by Grant Thornton (Special General Partnership), the Parent Company generated net profit of
     RMB 1,248,797,138.93, 10% of which was contributed to the statutory surplus reserve, namely RMB 124,879,713.89, the
     remainder of which, together with undistributed prots from last year RMB 564,932,141.19, subtracting cash dividends from
     last year RMB 288,675,388.05, is the current year Profits available for distribution to shareholders RMB 1,400,174,178.18.
     The Company plans to distribute cash dividends for the fiscal year 2021, based on the total number of shares for dividend
     distribution, which is dened by the total shares of Company, minus the shares in the Share Repurchase Account, on the equity
     registration date designated by the annual prot distribution plan. The Company plans to distribute cash dividend of RMB 1.50
     (tax inclusive) for every 10 shares of to all shareholders of the Company, and the remaining undistributed prots to be carried
     forward to the following year.

 4. Modication and adjustment of the cash dividend policy during the Reporting Period

     The Company's cash dividend policy was not modied or adjusted during the Reporting Period.




78
                                                                                                                 Annual Report
                                                                                                                         2021


(II) Special statement on cash dividend distribution policy
    √ Applicable □ N/A


     Whether it meets the requirements of the articles of association or the resolution of the general meeting      √ Yes □ No
     Are there dened and clear distribution qualications and proportions                                            √ Yes □ No
     Are there well-designed decision-making procedures and system                                                  √ Yes □ No
     Have independent directors performed their duties and role properly                                            √ Yes □ No
     Whether the minority shareholders have the chance to fully express their opinions and demands
                                                                                                                    √ Yes □ No
     Whether their legitimate rights and interests have been well protected


(III) If the Company made a profit in the Reporting Period and there's profit distributable by the parent company to
      shareholders, but the Company does not propose to distribute profits in cash, the Company shall explain the reason
      in detail, usage of the undistributed profit and usage plan
    □ Applicable √ N/A


XI Share incentive plan, employee share ownership scheme and other employee incentives
   of the Company and their effect
(1) Matters related to equity incentive scheme have been disclosed have been disclosed in the Provisional Announcements without
    progress or change in subsequent implementation
    √ Applicable □ N/A


                                 Overview                                                       Query index
     The number of options exercised was 3,848,413 by way of
                                                                        See the Announcement on 2021 Q1 Independent Exercise
     independent exercise from 1 January 2021 to 31 March 2021. As
                                                                        Results of the 2018 Share Options Incentive Scheme
     at 31 March 2021, the number of options cumulatively exercised
                                                                        of Joincare Pharmaceutical Group Industry Co., Ltd.
     and completing share transfer registration under the first grant
                                                                        & Changes in Shares (Lin 2021-044) disclosed by the
     and reserved grant of the 2018 Share Options Incentive Scheme
                                                                        Company on 2 April 2021 for details.
     of the Company was 18,595,839.
                                                                        See the Announcement on Resolutions of Joincare
                                                                        Pharmaceutical Group Industry Co., Ltd. at the Congress
                                                                        of Workers and Staff (Lin 2021-069), Announcement on
                                                                        Resolutions of Joincare Pharmaceutical Group Industry
     The Resolution on the First Phase Ownership Scheme under
                                                                        Co., Ltd. at the 48th Meeting of the 7th Session of the
     Medium to Long-term Business Partner Share Ownership
                                                                        Board (Lin 2021-068), Announcement on Resolutions
     Scheme of the Company (Draft) and its Summary and the
                                                                        of Joincare Pharmaceutical Group Industry Co., Ltd. at
     Resolution on the General Meeting for Granting Mandate
                                                                        the 36th meeting of the 7th Session of the Supervisory
     to the Board to Deal with Matters Related to the First Phase
                                                                        Committee (Lin 2021-067), and the First Phase Ownership
     Ownership Scheme under Medium to Long-term Business
                                                                        Scheme under Medium to Long-term Business Partner
     Partner Share Ownership Scheme of the Company were
                                                                        Share Ownership Scheme of Joincare Pharmaceutical
     considered and approved at the Congress of Workers and Staff,
                                                                        Group Industry Co., Ltd. (Draft) and its Summary
     the 48th Meeting of the 7th Session of the Board, and the 36th
                                                                        disclosed by the Company on 11 June 2021 for details.
     meeting of the 7th Session of the Supervisory Committee on 10
                                                                        See the Announcement on Resolutions of Joincare
     June 2021.
                                                                        Pharmaceutical Group Industry Co., Ltd. at the Second
     The said resolutions were considered and approved at the 2021
                                                                        Extraordinary General Meeting (Lin 2021-081) and the
     Second Extraordinary General Meeting on 29 June 2021.
                                                                        First Phase Ownership Scheme under Medium to Long-
                                                                        term Business Partner Share Ownership Scheme of the
                                                                        Company (Draft) and its Summary disclosed on 30 June
                                                                        2021 for details.




                                                                                                                              79
                                  Overview                                                     Query index
     The Resolution on Adjusting the Exercise Price of the 2018
     Share Options Incentive Scheme of the Company was
     considered and approved at the 49th Meeting of the 7th Session      See the Announcement on Adjusting the Exercise Price of
     of the Board and at the 37th Meeting of the 7th Session of          the 2018 Share Options Incentive Scheme of the Company
     the Supervisory Committee on 25 June 2021. Due to profit            by Joincare Pharmaceutical Group Industry Co., Ltd. (Lin
     distribution, the exercise price under the rst grant was adjusted   2021-080) disclosed on 26 June 2021 for details.
     to RMB7.74/share, while that under the reserved grant was
     adjusted to RMB10.16/share.
     The number of options exercised was 1,964,040 from 1 April
                                                                         See the Announcement on 2021 Q2 Independent Exercise
     2021 to 30 June 2021. As at 30 June 2021, the number of
                                                                         Results of the 2018 Share Options Incentive Scheme
     options cumulatively exercised and completing share transfer
                                                                         of Joincare Pharmaceutical Group Industry Co., Ltd.
     registration under the first grant and reserved grant of the
                                                                         & Changes in Shares (Lin 2021-084) disclosed by the
     2018 Share Options Incentive Scheme of the Company was
                                                                         Company on 2 July 2021 for details.
     20,559,879.
     The Resolution relating to Cancellation of Certain Share Options
     of the Company Granted but Not Yet Exercised under the 2018
     Share Option Incentive Plan was considered and approved at
     the 52nd Meeting of the 7th Session of the Board and the 38th
     meeting of the 7th Session of the Supervisory Committee of
     the Company on 10 August 2021. The share options under the          See the Announcement of Joincare Pharmaceutical Group
     first grant and reserved grant that have been granted but not       Industry Co., Ltd. on Cancellation of Certain Share
     yet exercised by some of the original incentive participants        Options of the Company Granted but Not Yet Exercised
     who had resigned and were therefore no longer qualified for         under the 2018 Share Option Incentive Plan (Lin 2021-
     the incentive were canceled. The number of share options            098) disclosed by the Company on 11 August 2021 for
     incentive participants under the first grant was adjusted from      details. Upon review and confirmation by the Shanghai
     233 to 211, the number of share options under the first grant       Branch of China Securities Depository and Clearing
     that have not been exercised was adjusted from 9,505,859 to         Corporation Limited, the said cancellation of share
     8,827,859, and 678,000 share options under the first grant were     options was completed on 17 August 2021.
     canceled. The number of share options incentive participants
     under the reserved grant was adjusted from 150 to 142, the
     number of share options under the reserved grant that have not
     been exercised was adjusted from 3,370,472 to 3,210,472, and
     160,000 share options under the reserved grant were canceled.
     The Resolution on Fulfillment of Exercise Conditions for the
     Second Exercise Period of the Reserved Grant under the 2018
     Share Options Incentive Scheme was considered and approved
     at the 53rd Meeting of the 7th Session of the Board and the 40th
                                                                         See the Announcement of Joincare Pharmaceutical Group
     meeting of the 7th Session of the Supervisory Committee of
                                                                         Industry Co., Ltd. on Fulfillment of Exercise Conditions
     the Company on 25 August 2021, with independent opinions
                                                                         for the Second Exercise Period of the Reserved Grant
     issued by independent directors of the Company, and review
                                                                         under the 2018 Share Options Incentive Scheme of the
     opinions issued by the Supervisory Committee. The number
                                                                         Company (Lin 2021-107) disclosed by the Company on
     of exercisable options during the second exercise period of the
                                                                         26 August 2021 for details.
     reserved grant under the 2018 Share Options Incentive Scheme
     of the Company was 2,935,000, and the exercise period was
     from 23 September 2021 to 22 September 2022 by way of
     independent exercise.




80
                                                                                                                Annual Report
                                                                                                                        2021


                                 Overview                                                     Query index
     The number of options exercised was 1,899,922 from 1 July
                                                                         See the Announcement of Joincare Pharmaceutical Group
     2021 to 30 September 2021. As at 30 September 2021, the
                                                                         Industry Co., Ltd. on 2021 Q3 Independent Exercise
     number of options cumulatively exercised and completing share
                                                                         Results of the 2018 Share Options Incentive Scheme
     transfer registration under the first grant and reserved grant of
                                                                         & Changes in Shares (Lin 2021-124) disclosed by the
     the 2018 Share Options Incentive Scheme of the Company was
                                                                         Company on 9 October 2021 for details.
     22,459,801.
     The Resolution relating to Cancellation of Certain Share Options
     under the 2018 Share Option Incentive Plan was considered and
                                                                         See the Announcement of Joincare Pharmaceutical Group
     approved at the 4th Meeting of the 8th Session of the Board and
                                                                         Industry Co., Ltd. on Cancellation of Certain Share
     the 3rd meeting of the 8th Session of the Supervisory Committee
                                                                         Options under the 2018 Share Option Incentive Plan (Lin
     of the Company on 15 November 2021. The share options that
                                                                         2021-136) disclosed by the Company on 16 November
     have been granted but not yet unlocked by some of the original
                                                                         2021 for details. Upon review and confirmation by the
     incentive participants who had resigned and were therefore no
                                                                         Shanghai Branch of China Securities Depository and
     longer qualied for the incentive should be canceled. The number
                                                                         Clearing Corporation Limited, the said cancellation of
     of share options incentive participants under the first grant
                                                                         60,000 share options was completed on 17 November
     was adjusted from 211 to 208, and 60,000 share options were
                                                                         2021.
     canceled. After completion of the cancellation, the number of
     share options under the rst grant was adjusted to 15,264,000.
     The Resolution on Fulfillment of Exercise Conditions for the
     Third Exercise Period of the First Grant under the 2018 Share
     Options Incentive Scheme was considered and approved at the
     5th Meeting of the 8th Session of the Board and the 4th meeting     See the Announcement of Joincare Pharmaceutical Group
     of the 8th Session of the Supervisory Committee of the Company      Industry Co., Ltd. on Fulfillment of Exercise Conditions
     on 29 November 2021, with independent opinions issued by            for the Third Exercise Period of the First Grant under the
     independent directors of the Company, and review opinions           2018 Share Options Incentive Scheme of the Company
     issued by the Supervisory Committee. The number of exercisable      (Lin 2021-140) disclosed by the Company on 30
     options during the third exercise period of the first grant under   November 2021 for details.
     the 2018 Share Options Incentive Scheme of the Company was
     7,263,000, and the exercise period was from 21 December 2021
     to 20 December 2022 by way of independent exercise.
     The number of options exercised was 2,370,065 from 1 October
                                                                         See the Announcement of Joincare Pharmaceutical Group
     2021 to 31 December 2021. As at 31 December 2021, the
                                                                         Industry Co., Ltd. on 2021 Q4 Independent Exercise
     number of options cumulatively exercised and completing share
                                                                         Results of the 2018 Share Options Incentive Scheme
     transfer registration under the first grant and reserved grant of
                                                                         & Changes in Shares (Lin 2022-001) disclosed by the
     the 2018 Share Options Incentive Scheme of the Company was
                                                                         Company on 6 January 2022 for details.
     24,829,866.


(2) Incentives not disclosed in the Provisional Announcements or with subsequent progress
    Equity incentives
    □ Applicable √ N/A

    Others
    □ Applicable √ N/A

    Employee share ownership scheme
    □ Applicable √ N/A


    Other incentive Program
    □ Applicable √ N/A




                                                                                                                                 81
 (3) Equity incentives granted to directors and senior management during the Reporting Period
     √ Applicable □ N/A
                                                                                                                  Unit: 10,000 shares
                                                       Number of     Number of     Number of              Number         Market
                                        Number of
                                                    newly granted    exercisable    exercised Exercise    of share   price at the
                                     share options
                                                     share options      options       options     price    options    end of the
       Name        Title                held at the
                                                        during the    during the   during the   (RMB        held at   Reporting
                                      beginning of
                                                        Reporting     Reporting    Reporting     Yuan) the end of         Period
                                          the year
                                                            Period        Period       Period           the period (RMB Yuan)
       Yu Xiong    Director,                                                               13       7.89
                                                37               0           37                                  14          12.84
                   President                                                               10       7.74
                   Director, Vice
       Lin Nanqi                                48              0            48            24       7.74         24          12.84
                   President
                   Director, Vice
       Qiu         President,
                                                36              0            36            18       7.89         18          12.84
       Qingfeng    Chief Financial
                   Ocer
                Vice President,
      Zhao
                Board                           36              0            36            18       7.89         18          12.84
      Fengguang
                Secretary
      Total        /                          157               0           157            83          /         74                /


 (4) Performance assessment mechanism for senior management during the Reporting Period, and the development and
     implementation of incentive scheme
     √ Applicable □ N/A

       According to the relevant provisions of the Company such as the“Remuneration and Performance Appraisal Management
     System for Senior Management”, plans on remuneration of senior management are set based on the operating revenue and
     profit of the Company in 2021 and the corresponding personal performance of each senior management. The plans shall be
     reviewed and approved by the Remuneration C ommittee of the Board and then be submitted to the Board for review and
       decision. During the Reporting Period, Senior management of the Company perform their duties in strict accordance with the
     “Company Law”,“Articles of Association”and other relevant regulations, actively implement the relevant resolutions of
     the Company's General meetings and the Board meetings, actively adjust business plans under the guidance of the board of
       directors, continuously strengthen internal control management, and strive to Improve the Company's core competitiveness.


XII Development and implementation of internal controls during the Reporting Period
      √ Applicable □ N/A


      During the Reporting Period, the Company carried out standard operation and risk control in strict accordance with the laws
      and regulations in China and the internal control system of the Company. The Company established a rigorous internal control
      management system, continued to optimize and improve the internal control system by combining the industry characteristics
      and the actual operation of the Company, enhanced its decision-making efficiency, and ensured the legal compliance of
      business management and the security of corporate assets, facilitating the steady implementation of strategies of the Company.
      Thanks to an effective internal control mechanism, the Company can prevent, timely identify and correct any deviation in
      the operation and management, and can reasonably ensure the security and integrity of corporate assets, and the authenticity,
      accuracy and completeness of accounting information, safeguarding the interests of the Company and all shareholders.




82
                                                                                                                Annual Report
                                                                                                                        2021


    Based on the identification of material deficiencies of internal control of the Company, there was no material deficiency or
    significant deficiency of internal control over financial reporting and non-financial reporting in the Company for the year
    2021. Through operation, analysis and evaluation of the internal control system, the Company effectively prevented business
    management risks, and promoted the achievement of internal control objectives. Looking ahead, the Company will continue
    to improve the internal control system, standardize its implementation, strengthen the supervision and inspection over internal
    control, and promote the healthy and sustainable development of the Company.

    See the Risk Management and Internal Control Self-Assessment Report 2021 of Joincare Pharmaceutical Industry Group Co.,
    Ltd. disclosed by the Company on the website of Shanghai Stock Exchange (www.sse.com.cn) on 31 March 2022 for details.

    Statement on material loopholes in internal controls during the Reporting Period
    □ Applicable √ N/A


XIII Management and control of subsidiaries during the Reporting Period
    √ Applicable □ N/A


    The Company formulated relevant subsidiary management rules, such as the Detailed Rules for Standardized Operation and
    Management of Subsidiaries, to strengthen internal control of wholly-owned and majority-owned subsidiaries by specifying
    their governance structure, management of three meetings, outbound investment, special transactions, legal person's
    authorization and relevant issues, to improve the Company's overall operating eciency and risk control capability. During the
    Reporting Period, the Company exercised management and control over its subsidiaries in accordance with the Company Law,
    the Articles of Association and other relevant laws and regulations. First, it provided guidance for the subsidiaries as to how
    to improve the corporate governance structure, and how to revise and improve the Articles of Association and other relevant
    systems in accordance with relevant laws and regulations; second, through internal training such as training on connected
    transactions, the Company urged subsidiaries to report to the Company on connected transactions, external guarantee and
    other major matters in advance; third, the Company updated the internal control manual and related materials, to improve the
    internal control system, and strengthen implementation and enhance the eectiveness of internal control.


XIV Related information on internal control audit report
    √ Applicable □ N/A


    In accordance with relevant standards, guidelines and regulatory documents, and subject to approval by the audit committee
    of the Board of Directors, the Board of Directors and the general meeting, the Company engaged Grant Thornton China
    (special general partnership) to conduct internal control audit in 2021. In accordance with the Basic Standards for Enterprise
    Internal Control and the Application Guidelines for Enterprise Internal Control, Grant Thornton China conducted audit of the
    effectiveness of internal control over financial reporting of the Company and its subsidiaries as of 31 December 2021, and
    issued a standard internal control audit report with unqualied opinion. See the Internal Control Audit Report 2021 of Joincare
    Pharmaceutical Industry Group Co., Ltd. disclosed by the Company on the website of Shanghai Stock Exchange (www.sse.
    com.cn) on 31 March 2022 for details.

    Disclosure of internal control auditor's report: Yes

    Types of internal control auditor's opinion: Standard unqualied opinion




                                                                                                                                83
XV Rectification of self-examined deviations in the Special Action for Governance of Listed
   Companies

 1. Optimization of the meeting convening methods of the Board of Directors and Special Committees of the Board

     Situation description: At present, the Board of Directors and the special committees mostly hold meetings through electric
     means which is not conducive to full expression of opinions by directors.

     Rectication measures: In order to ensure that directors can fully express their opinions, the Company will increase the number
     of on-site meetings of the Board of Directors and its specialized committees. In particular, on-site meetings or on-site + electric
     means will be held for matters related to major asset purchase or sale or major connected transactions in the future.

 2. Improvement of the audit institution selection and engagement review process

     Situation description: The special self-inspection found that the Company engaged the audit institution based on public
     information on its professional competence and integrity, without consulting the record of integrity of the audit institution in
     the securities and futures market through China Securities Regulatory Commission in advance.

     Rectification measures: From 2021, in addition to public information, the Company would, before selecting and engaging an
     audit institution, consult the records of integrity of the audit institution and relevant certied public accountants to be engaged
     in the securities and futures market as maintained by Shenzhen Securities Regulatory Bureau, to fully learn about its practicing
     experience, professional competence and integrity.


XVI Others
     □ Applicable √ N/A




84
    Chapter 5
    Environmental and Social Responsibility


I Environmental information

(I) Environmental issues of companies and their major subsidiaries belonging to key pollutant discharging units as
    announced by the environmental protection department
    √ Applicable □ N/A

1. Pollution discharge information
   √ Applicable □ N/A

i. Jiaozuo Joincare


                                                                                                     Pollutant                  Total
                                                                                                                    Total
    Name of        Name of major                       Number of Distribution        Discharge       discharge             amount of
                                         Mode of                                                               amount of               Excessive
    company or     pollutants and                      discharge of discharge     concentration      standards              discharge
                                         discharge                                                              discharge              discharge
    subsidiary     specic pollutants                    outlets outlets                 (mg/L)    implemented               approved
                                                                                                                     (t/a)
                                                                                                        (mg/L)                   (t/a)
                   Chemical oxygen                                Master outlet
                                                                                        115.69            220     700.123      942.1         Nil
    Jiaozuo        demand                                         in sewage
                                        Continuous         1
    Joincare       Ammonia                                        treatment
                                                                                          16.2             35      97.685      105.3         Nil
                   nitrogen                                       workshop


ii. Taitai Pharmaceutical


                                                                                                     Pollutant                  Total
                                                                                                                    Total
    Name of        Name of major                       Number of Distribution        Discharge       discharge             amount of
                                         Mode of                                                               amount of               Excessive
    company or     pollutants and                      discharge of discharge     concentration      standards              discharge
                                         discharge                                                              discharge              discharge
    subsidiary     specic pollutants                    outlets outlets                 (mg/L)    implemented               approved
                                                                                                                     (t/a)
                                                                                                        (mg/L)                   (t/a)
                   Chemical oxygen
                                                                                         28.38            345        0.24      19.34         Nil
                   demand                                         The
                   Biochemical                                    southwest
                                        Intermittent       1                              48.4            150        0.35         Nil        Nil
                   oxygen demand                                  side of the
    Taitai         Suspended solids                               factory                   5.3           250       0.042         Nil        Nil
    Pharmaceutical pH value                                                               8.06          6~9            /         Nil        Nil
                   Sulfur dioxide                                 Chimney on                0.9            50       0.009         Nil        Nil
                   Nitrogen oxide                                 the roof of            11.36            150        0.12         Nil        Nil
                                        Intermittent       1
                                                                  the boiler
                   Particulate matter                                                    15.46             20        0.22         Nil        Nil
                                                                  room




                                                                                                                                             85
 iii. Haibin Pharma


                                                                                                        Pollutant                  Total
                                                                                                                       Total
     Name of          Name of major                       Number of Distribution        Discharge       discharge             amount of
                                            Mode of                                                               amount of               Excessive
     company or       pollutants and                      discharge of discharge     concentration      standards              discharge
                                            discharge                                                              discharge              discharge
     subsidiary       specic pollutants                    outlets outlets                 (mg/L)    implemented               approved
                                                                                                                        (t/a)
                                                                                                           (mg/L)                   (t/a)
                      Chemical oxygen
                                                                     Master                 53.85            500        3.07       41.65        Nil
                      demand
                                                              1      outlet for
                      Ammonia
                                                                     sewage                  3.14             45        0.18     3.7485         Nil
                      nitrogen
                      Particulate matter                             Discharge                 2.4            20        0.05         Nil        Nil
                      Sulfur dioxide                                 outlet of                  0             50           0         Nil        Nil
                                                              1
                                                                     boiler
                      Nitrogen oxide                                                           21            150        0.43         Nil        Nil
                                                                     exhaust gas
     Haibin Pharma                         Continuous
                                                                     Discharge
                                                                     outlet of
                                                                     process
                      Volatile organic                               organic
                                                              2                                3.3           100         0.3       9.156        Nil
                      compounds                                      exhaust gas
                                                                     and tank
                                                                     farm exhaust
                                                                     gas


 iv. Xinxiang Haibin


                                                                                                        Pollutant                  Total
                                                                                                                       Total
     Name of          Name of major                       Number of Distribution        Discharge       discharge             amount of
                                            Mode of                                                               amount of               Excessive
     company or       pollutants and                      discharge of discharge     concentration      standards              discharge
                                            discharge                                                              discharge              discharge
     subsidiary       specic pollutants                    outlets outlets                 (mg/L)    implemented               approved
                                                                                                                        (t/a)
                                                                                                           (mg/L)                   (t/a)
                      Chemical oxygen                                Master outlet
                                                                                            62.30            220      11.286       14.81        Nil
     Xinxiang         demand                                         in sewage
                                           Continuous         1
     Haibin           Ammonia                                        treatment
                                                                                             0.79             35       0.838        1.66        Nil
                      nitrogen                                       workshop


 v. Fuzhou Fuxing


                                                                                                     Pollutant                  Total
                                                                                                                    Total
     Name of          Name of major                       Number of Distribution        Discharge    discharge             amount of
                                            Mode of                                                            amount of               Excessive
     company or       pollutants and                      discharge of discharge     concentration   standards              discharge
                                            discharge                                                           discharge              discharge
     subsidiary       specic pollutants                    outlets outlets                 (mg/L) implemented               approved
                                                                                                                     (t/a)
                                                                                                        (mg/L)                   (t/a)
                      Chemical oxygen                                The
                                                                                            19.43            100       19.41       124.5        Nil
                      demand                                         northwest
     Fuzhou Fuxing                         Intermittent       1
                      Ammonia                                        side of the
                                                                                            0. 273            15        0.27        18.7        Nil
                      nitrogen                                       factory




86
                                                                                                                        Annual Report
                                                                                                                                2021


    Note: The discharge concentration represents the actual discharge concentration, and the standards implemented represent
    the standards for discharge to the environment by Jiangyin sewage plant ( 江 阴 污 水 处 理 厂 ) (i.e. COD ≤ 100mg/L, ammonia
    nitrogen ≤ 15mg/L), and the agreed standard for discharge of COD and ammonia nitrogen from the company to Jiangyin
    sewage plant shall be ≤ 500mg/L and ≤ 60mg/L, respectively. The data was obtained from Fuqing Environmental Protection
    Bureau.

vi. Xinbeijiang Pharmaceutical


                                                                                                Pollutant                  Total
                                                                                                               Total
    Name of         Name of major                      Number of Distribution      Discharge    discharge             amount of
                                         Mode of                                                          amount of               Excessive
    company or      pollutants and                     discharge of discharge   concentration   standards              discharge
                                         discharge                                                         discharge              discharge
    subsidiary      specic pollutants                   outlets outlets               (mg/L) implemented               approved
                                                                                                                (t/a)
                                                                                                   (mg/L)                   (t/a)
                    Chemical oxygen
                                                                  Sewage                86.4          240       70.62        Nil        Nil
    Xinbeijiang     demand
                                        Intermittent       1      treatment
    Pharmaceutical Ammonia
                                                                  workshop               6.8           70        5.61        Nil        Nil
                   nitrogen


    Note: The discharge concentration represents the concentration of discharge into Qingyuan Henghe Sewage Treatment
    Plant ( 清 远 横 荷 污 水 处 理 厂 ), while the standard adopted for discharge represents the standard stipulated in the pollutant
    discharge license of the company, i.e. COD ≤ 240mg/L, ammonia nitrogen ≤ 70mg/L. The data was obtained from Qingyuan
    Environmental Protection Bureau.

vii. Livzon Hecheng


                                                                                                 Pollutant
                                                                                                                           Total
                                                                                   Discharge     discharge     Total
    Name of        Name of major                       Number of Distribution                                         amount of
                                         Mode of                                concentration    standards amount of              Excessive
    company or     pollutants and                      discharge of discharge                                          discharge
                                         discharge                                   (mg/L)/ implemented discharge                discharge
    subsidiary     specic pollutants                    outlets outlets                                                approved
                                                                                  (mg/m3)        (mg/L)/        (t)
                                                                                                                            (t/a)
                                                                                               (mg/m3)
                   Chemical oxygen
                                                                  Wastewater         88.505           192      18.258        Nil        Nil
                   demand
                                        Intermittent       1      treatment
                   Ammonia nitrogen
                                                                  station             8.757            40       1.478        Nil        Nil
                   (NH3-N)
                   Sulfur dioxide                          3      Boiler room           5.67           50      0.1427        Nil        Nil
                   Nitrogen oxide                          3      Boiler room       57.0625           150      1.5497        Nil        Nil
    Livzon         Particulate matter                      3      Boiler room           1.36           20      0.0361        Nil        Nil
    Hecheng        Hydrogen chloride                       7      Workshop              1.41          100      0.4635        Nil        Nil
                                        Organized
                   Non-methane
                                        continuous         7      Workshop            15.93            60      7.5421                   Nil
                   hydrocarbons
                                         emission                                                                          77.76
                   Non-methane
                                                           1      RTO                   8.56           60      1.5622                   Nil
                   hydrocarbons
                   Nitrogen oxide                          1      RTO                    50           200      8.3813        Nil        Nil
                   Sulfur dioxide                          1      RTO                     3           200      0.8233        Nil        Nil




                                                                                                                                         87
     Notes:
     1. The discharge concentration of pollutants in waste water represents the average concentration by online monitoring from
     the master discharge outlet by the company into South District Sewage Treatment Plant, while the standard adopted for
     discharge represents the standard stipulated in the pollutant discharge license of the company, i.e. COD ≤ 192mg/L, ammonia
     nitrogen ≤ 40mg/L.
     2. The discharge concentration of pollutants in the discharge outlet of waste gas represents the average concentration detected
     by a qualified third party engaged, of which the boiler exhaust adopted the Emission Standard for Boiler Atmospheric
     Pollutants in Guangdong Province (DB 44/765-2019) (《 广 东 省 锅 炉 大 气 污 染 物 排 放 标 准 》(DB 44/765-2019)), the
     workshop and wastewater treatment station emission complied with the Air Pollutant Discharge Standards for Pharmaceutical
     Industry (《制药工业大气污染物排放标准》) (GB 37823-2019).

viii. Gutian Fuxing


                                                                                                      Pollutant                  Total
                                                                                                                     Total
     Name of          Name of major                      Number of Distribution       Discharge       discharge             amount of
                                          Mode of                                                               amount of               Excessive
     company or       pollutants and                     discharge of discharge    concentration      standards              discharge
                                          discharge                                                              discharge              discharge
     subsidiary       specic pollutants                   outlets outlets                (mg/L)    implemented               approved
                                                                                                                        (t)
                                                                                                         (mg/L)                   (t/a)
                   Chemical oxygen                                  Southeastern
                                                                                          50.66            120     13.463         108         Nil
     Gutian Fuxing demand           Continuous               1      part of the
                   Ammonia nitrogen                                 factory zone         11.884             35       3.162       31.5         Nil


     Note: The discharge concentration represents the concentration of ultimate discharge into the environment, while the standard
     adopted for discharge represents the standard stipulated in the pollutant discharge license of the company, i.e. COD ≤ 120mg/L,
     ammonia nitrogen ≤ 35mg/L.

 ix. Livzon Limin


                                                                                                   Pollutant                  Total
                                                                                                                  Total
     Name of          Name of major                      Number of Distribution       Discharge    discharge             amount of
                                           Mode of                                                           amount of                  Excessive
     company or       pollutants and                     discharge of discharge    concentration   standards              discharge
                                           discharge                                                          discharge                 discharge
     subsidiary       specic pollutants                   outlets outlets                (mg/L) implemented               approved
                                                                                                                     (t)
                                                                                                      (mg/L)                   (t/a)
                      Chemical oxygen                               Wastewater
                                                                                          16.75            110      4.988         Nil         Nil
     Livzon Limin     demand              Intermittent       1      treatment
                      Ammonia nitrogen                              station               0.516             15      0.152         Nil         Nil


     Note: The wastewater of Livzon Group Limin Pharmaceutical Manufacturing Factory ( 丽 珠 集 团 利 民 制 药 厂 ) was
     discharged into Shaoguan Second Sewage Treatment Plant ( 韶 关 市 第 二 污 水 处 理 厂 ) and the standard adopted for pollutant
     discharge represented the standard stipulated in the pollutant discharge license of the company, i.e. COD ≤ 110mg/L, ammonia
     nitrogen ≤ 15mg/L, while the data detected by third party inspection rm was adopted as the discharge concentration.




88
                                                                                                                           Annual Report
                                                                                                                                   2021


x. Livzon Pharmaceutical Factory


                                                                                                  Pollutant                  Total
                                                                                                                 Total
    Name of         Name of major                      Number of Distribution        Discharge    discharge             amount of
                                         Mode of                                                            amount of                 Excessive
    company or      pollutants and                     discharge of discharge     concentration   standards              discharge
                                         discharge                                                           discharge                discharge
    subsidiary      specic pollutants                   outlets outlets               (mg/L) implemented               approved
                                                                                                                    (t)
                                                                                                  (mg/L)                    (t/a)
                                                                  Wastewater
                    Chemical oxygen
                                                           1      treatment              12.83           120       2.27         Nil         Nil
    Livzon          demand
                                                                  station
    Pharmaceutical                      Intermittent
                                                                  Wastewater
    Factory        Ammonia
                                                           1      treatment              0.369            20       0.06         Nil         Nil
                   nitrogen
                                                                  station


    Note: The discharge concentration of pollutants in the wastewater discharge outlet represents the average concentration
    detected by a qualified third party engaged, by implementing the strictest of Schedule 2 Water Pollutant Discharge
    Concentration Limits for Newly-Built Enterprises ( 表 2 新 建 企 业 水 污 染 物 排 放 浓 度 限 值 ) of the Emission Standard for
    Pharmaceutical Industrial Water Pollutants from Mixing and Formulation Category (《混装制剂类制药工业水污染物排放
    标 准 》) (GB 21908-2008), Schedule 2 Water Pollutant Discharge Concentration Limits for Newly-Built Enterprises ( 表 2 新
    建企业水污染物排放浓度限值 ) of Discharge Standards for Biopharmaceutical Industrial Wastewater (《生物工程类制药工
    业水污染物排放标准》) (GB 21907-2008), or the level 1 of phase II standard of Guangdong Provincial Capping on Polluted
    Euents Discharge (《广东省水污染物排放限值》) (DB44/26–2001).

xi. Ningxia Pharmaceutical


                                                                                                   Pollutant
                                                                                                                             Total
                                                                                     Discharge     discharge     Total
    Name of         Name of major                      Number of Distribution                                           amount of
                                         Mode of                                  concentration    standards amount of                Excessive
    company or      pollutants and                     discharge of discharge                                            discharge
                                         discharge                                     (mg/L)/ implemented discharge                  discharge
    subsidiary      specic pollutants                   outlets outlets                                                  approved
                                                                                    (mg/m3)        (mg/L)/        (t)
                                                                                                                              (t/a)
                                                                                                 (mg/m3)
                    Chemical oxygen                               Sewage
                                                                                          105            200     111.59         Nil         Nil
                    demand                                        treatment
                                                           1      workshop on
                    Ammonia
                                                                  north side of            0.8            25       0.82         Nil         Nil
                    nitrogen
                                                                  factory zone
                    Sulfur dioxide                                Boiler                    47          200       24.79    156.816          Nil
                    Nitrogen oxide                                workshop on             102           200       87.76    156.816          Nil
    Ningxia                                                1
                                        Continuous                north side of
    Pharmaceutical Particulate matter                                                       14            30        8.2     23.522          Nil
                                                                  factory zone
                                                                  4 outlets for
                                                                  fermentation,
                    Volatile organic                              3 outlets for
                                                           9                               8.5          100          22     79.535          Nil
                    compounds                                     renery and
                                                                  2 outlets for
                                                                  sewage




                                                                                                                                             89
     Notes:
     1. The discharge concentration of wastewater represents the concentration of ultimate discharge to the environmental
     protection control center of Ningxia Xin'an Technology Co., Ltd. ( 宁 夏 新 安 科 技 有 限 公 司 ) (“Xin'an Company”), the
     standard adopted for pollutant discharge was the standard stipulated in the pollutant discharge license of the company and the
     amount of discharge was calculated by the amount received by Xin'an Company. In respect of the total amount of approved
     discharge, since the company adopted indirect discharge, the local government of Ningxia cancelled the limitation of total
     discharge of chemical oxygen demand and ammonia nitrogen of all indirect discharge enterprises, and the total amount index
     was directly allocated to sewage treatment plants in the pharmaceutical industrial park established by the government after the
     renewal of the pollution discharge license.
     2. The emission concentration of boiler exhaust gas represents the self-monitoring average concentration throughout the
     year, the standard adopted for discharge was the standard stipulated in the pollutant discharge license of the company and
     the amount of discharge was calculated by the amount indicated by online monitoring. The concentration of volatile organic
     compounds (VOCs) represents the concentration of ultimate discharge to the environment (self-monitoring concentration), the
     adopted standard was the standard limits stipulated in Schedule I of the Air Pollutant Discharge Standards for Pharmaceutical
     Industry (《制药工业大气污染物排放标准》) (GB37823-2019) and the amount of discharge was calculated by the amount
     of exhaust gas emissions and the discharge concentration recorded by the monitoring report.

xii. Jiaozuo Hecheng


                                                                                                   Pollutant                  Total
                                                                                                                  Total
     Name of        Name of major                      Number of Distribution         Discharge    discharge             amount of
                                        Mode of                                                              amount of                 Excessive
     company or     pollutants and                     discharge of discharge      concentration   standards              discharge
                                        discharge                                                             discharge                discharge
     subsidiary     specic pollutants                   outlets outlets                  (mg/L) implemented               approved
                                                                                                                     (t)
                                                                                                      (mg/L)                   (t/a)
                    Chemical oxygen                               Master outlet
                                                                                       109.049            220      9.396        60.8         Nil
     Jiaozuo        demand                                        in industrial
                                        Continuous         1
     Hecheng        Ammonia                                       wastewater
                                                                                          3.911            35      0.337         8.8         Nil
                    nitrogen                                      workshop


     Note: The discharge concentration and the total amount of discharge represent the concentration and total amount of ultimate
     discharge into the downstream sewage treatment plant, and the source is online monitoring data.

xiii. Shanghai Livzon


                                                                                                    Pollutant
                                                                                                                              Total
                                                                                      Discharge     discharge     Total
     Name of       Name of major                       Number of Distribution                                            amount of
                                        Mode of                                    concentration    standards amount of              Excessive
     company or    pollutants and                      discharge of discharge                                             discharge
                                        discharge                                       (mg/L)/ implemented discharge                discharge
     subsidiary    specic pollutants                   outlets   outlets                                                  approved
                                                                                     (mg/m3)        (mg/L)/        (t)
                                                                                                                               (t/a)
                                                                                                  (mg/m3)
                   COD                                            Master outlet           50.25          500        2.97         Nil         Nil
                                        Intermittent 1
                   Ammonia nitrogen                               in the park             27.98            40       1.77         Nil         Nil
                                                                  No. 5 and 6
                   Particulate matter                  2          outlet on the               5            20      0.015       0.054         Nil
     Shanghai
                                        Organized                 roof
     Livzon
                                        intermittent              No.1, 2, 3, 4,
                                        discharge                 7, 8, 9 and 10
                   VOCs                                8                                   1.98            60      0.277       2.145         Nil
                                                                  outlets on the
                                                                  roof




90
                                                                                                                Annual Report
                                                                                                                        2021


    Note: The discharge concentration was the average of monthly third-party monitoring data, and the amount of discharge was
    the cumulative sum of monthly discharge. The discharge of VOCs and particulate were in accordance with the Air Pollutant
    Discharge Standards for Pharmaceutical Industry (《制药工业大气污染物排放标准》) (GB37823-2019), and the discharge
    of COD and Ammonia nitrogen were implemented in accordance with the comprehensive sewage discharge standard
    DB31/199-2018. Shanghai Livzon Pharmaceutical Manufacturing Co., Ltd. ( 上海丽珠制药有限公司 ) was among other key
    pollutant discharge units, but not among the key pollutant discharge units of water environment and atmospheric environment.

2. Construction and operation of pollution preventive facilities
   √ Applicable □ N/A


    Name of company
                                                Construction and operation of pollution preventive facilities
    or subsidiary
                         Exhaust gas: The treatment process of“water spray + acid spray + alkali spray + mist eliminator +
                         dry filter + adsorption concentrator + RCO”+“secondary alkali spray”was adopted for fermentation
                         exhaust gas. The treatment process of“bag type dust collector”was adopted for proportioning process
                         dust-laden exhaust gas. The treatment process of“secondary alkali spray”was adopted for exhaust
                         gas treatment facilities in wastewater treatment station. The treatment process of“alkali adsorption”
                         was adopted for process acid waste gas. The treatment process of“tertiary nned condenser + bag type
                         dust collector + secondary alkali spray + RTO”“-20 ℃ condensation + activated carbon adsorption
                         device (including regenerating device) + RTO”“adsorption device (including regenerating device)
                         + secondary alkali spray + biological uptake + secondary alkali spray”“secondary alkali spray +
    Jiaozuo Joincare
                         biological uptake + secondary alkali spray”was adopted for process organic exhaust gas. 15 discharge
                         outlets were constructed. All of them enable stable and up-to-standard discharge through self-
                         monitoring.
                         Wastewater: The treatment process of“regulating pool + hydrolysis acidication pool + UASB + (CASS
                         + air flotation) / modified A/O + secondary settling tank + coagulating sedimentation”was primarily
                         adopted. Standard wastewater outlets were set; online automatic monitoring control system was installed
                         at outlets for real-time monitoring of COD, ammonia nitrogen, total nitrogen, pH, and flow. At present,
                         wastewater treatment process sections can be stably operated. Moreover, wastewater control factors can
                         be stably emitted in compliance with the required standard.
    Taitai
                         No new facilities were set up. Facilities functioned properly.
    Pharmaceutical
    Haibin Pharma        Pollution preventive facilities functioned properly and ensured up-to-standard discharge.
                         1.Wastewater: The wastewater treatment system with daily processing capacity of 600 tonnes through
                         A/O process designed by East China University of Science and Technology started operation in April
                         2016 and functioned properly in the rst half of 2021. A set of MVR concentration wastewater treatment
                         plant was added in April 2020, which has been functioning properly in the first half of 2021. From
                         March to June 2021, a set of lift aerator system and a set of magnetic levitation blower were added in the
                         biochemical system, and they have been put into operation and functioning properly at present. A new
                         sewage anaerobic treatment system had been building in 2021 and is currently under construction.
                         2.Exhaust gas: The 40000m/h regenerative oxidation exhaust gas treatment system designed by
                         Jiangsu Ruiding started operation on 2 November 2019 and is functioning properly in 2021. After
    Xinxiang Haibin
                         reconstruction of dry tail gas self-circulating process, the activated carbon adsorption device for high
                         concentration waste gas designed by Beijing Rixin Daneng Technology Co., Ltd. has been functioning
                         properly in 2021 and solvent recovery amount was increased. After alkali spray and water spray, the
                         exhaust gas from biochemical aerobic process of wastewater treatment was emitted in compliance
                         with the required standard. A set of tetrahydrofuran membrane recovery system was added for high
                         concentration exhaust gas treatment of six workshops, which has been functioning properly in 2021. An
                         new exhaust gas membrane recovery system was added to the third workshop and the system operates
                         properly in 2021
                         3.Solid wastes were disposed of in compliance with the relevant requirements.


                                                                                                                                91
     Name of company
                                               Construction and operation of pollution preventive facilities
     or subsidiary
                        The company strictly complies with the“Three-Simultaneous”system of environmental protection
                        by collecting and treating“Three Wastes (waste water, exhaust gas and solid waste)”according to
                        requirements, and employs an advanced sewage treatment process known as“Regulating pool +
                        Hydrolysis acidification tank + SBR + Air float”. After the sewage has gone through the above
                        treatment process, all indicators are stable and satisfy the discharge standard. After meeting the discharge
     Fuzhou Fuxing      standards, the sewage is discharged to Jiangyin sewage plant operated by Fujian Huadong Water
                        Treatment Co., Ltd. ( 福 建 华 东 水 务 有 限 公 司 ) via sewage pipe network at the industrial park area for
                        further treatment. Two sets of QC waste gas treatment devices have been newly constructed in 2021,
                        in which the waste gas was treated through water spray and activated carbon adsorption method and
                        emitted after meeting the emission standards. For details on circumstances in previous years, please refer
                        to the relevant content of the 2020 annual report of Livzon.
                        The“Three Wastes”were collected and treated effectively in strict compliance with the“Three
                        Simultaneous”system. The sewage treatment facilities with an investment amount of over RMB30
                        million have a designed processing capacity of 3,000t/d and adopt the treatment process of“Pre-
                        treatment + Aerobic pool + Hydrolysis acidification tank + SBR + Catalytic oxidation + Air float”.
                        In 2021, an aggregate amount of over RMB6 million was invested to the treatment and improvement
                        projects of sewage, waste gas, noise and solid waste storage sites in the factory, including more than
     Xinbeijiang
                        40 environmental protection improvement projects, such as the power cooling tower noise reduction
     Pharmaceutical
                        project, the installation of the boiler inlet muer, the enclosure of MVR fans, the renovation of sewage
                        tank in workshop 1 of department III, the replacement of the aeration pipes of the biological lter of the
                        sewage station, and the renovation of the pretreatment waste gas of the sewage treatment station, so as
                        to reduce the impact of factory noise on the surrounding area through controlling from the source, while
                        eliminating the smell emission of workshops, sewage and solid waste storage sites to ensure the stable
                        operation of sewage treatment system.
                         The“Three Wastes”were treated in a centralized and effective manner in strict compliance with the
                       “Three Simultaneous”system and the maintenance and management of pollution preventive facilities
                         were enhanced to ensure that emission of pollutants was stable and in compliance with the required
                         standard. The treatment process of“pre-treatment of drainage from the production process + hydrolytic
                         acidification + upflow anaerobic sludge blanket (UASB) + advanced oxidation + CASS process + air
                         floatation/ozonation advanced treatment”was adopted. Treated sewage was discharged through the
                       municipal sewage pipeline network into Zhuhai Leaguer Environmental Protection Co., Ltd. ( 珠 海
                         力 合 环 保 有 限 公 司 ) (water purication plant in the South District). In 2021, RMB4.88 million has
     Livzon Hecheng      be invested in environmental protection projects; RMB2.34 million has be invested in the collection
                         and pretreatment of high-concentration exhaust gas from various workshops; RMB0.8 million has be
                         invested in increase washing to eliminate odors from RTO-treated waste gas; Valves; RMB0.63 million
                         has be invested in RTO maintenance, including valves, ceramics and internal anti-corrosion replacement
                         and upgrade, etc.; RMB0.65 million has be invested to purchase liquid nitrogen cryogenic device for
                       treatment of chloroform waste gas in Workshop 102; RMB0.26 million has be invested to collect and
                       treat laboratory and R&D waste gas; and RMB0.20 million has be invested for maintenance of GAC
                       activated carbon adsorption and desorption attached device. For details on circumstances in previous
                       years, please refer to the relevant content of the 2020 annual report of Livzon.




92
                                                                                                          Annual Report
                                                                                                                  2021


Name of company
                                         Construction and operation of pollution preventive facilities
or subsidiary
                  At the same time when the enterprise started production, the“Three Wastes”were collected and treated
                  effectively in accordance with the requirements of the“Three Simultaneous”system of environmental
                  protection. This involves a designed sewage treatment capacity of 1,200 t/d, adoption of the advanced
                  “A/O + SBR + nitrogen removal by denitrification + Fenton decolorizing + air flotation”sewage
                  treatment process, 6,000 m3 of eective reservoir capacity of the treatment system and more than 20 sets
                    of treatment equipment with 350 KW installed capacity to improve the water treatment process, thus
Gutian Fuxing     ensuring that all wastewater treatment indicators are stable and satisfy the discharge standard. Treated
                  sewage that reaches the grade II discharge standard is directly discharged into Minjiang River. The
                  hazardous wastes of the company are entrusted to qualied companies for compliant disposal according
                    to the requirements of environmental impact assessment and acceptance inspection opinions. In 2021,
                  RMB0.6 million was invested to upgrade the environmentally friendly sludge pressing system to reduce
                  the moisture content of the sludge and the amount of sludge produced. For details on circumstances in
                  previous years, please refer to the relevant content of the 2020 annual report of Livzon.
                   The“Three Simultaneous”system was strictly implemented by the company for the treatment of“Three
                   Wastes”by collecting and treating the“Three Wastes”eectively. The investment for sewage treatment
                   facilities was over RMB13 million with designed processing capacity of 1,500t/d and adopted the
                   treatment process of“Pre-treatment + Hydrolysis acidification tank + Facultative tank + Aerobic pool
                   + Secondary sedimentation”, and the sewage after treatment was discharged through the municipal
Livzon Limin
                   pipeline network into Shaoguan Second Sewage Treatment Plant ( 韶关市第二污水处理厂 ). In respect
                   of exhaust gas treatment, biomass boilers were all replaced by gas boilers. The technical transformation
                   project of the R&D center has installed waste gas treatment facilities such as activated carbon adsorption
                   and acid mist spray tower. In respect of control of noise pollution, RMB100,000 was invested to
                   construct noise segregation wall to reduce noise pollution.
                   The“Three Simultaneous”system was strictly implemented by the company for the treatment of“Three
                   Wastes”by collecting and treating the“Three Wastes”eectively. For wastewater: an investment of over
                   RMB10 million was made for phase I and phase II sewage treatment station with designed processing
Livzon
                   capacity of 1,000t/d, which adopted the CASS process for phase I and the AO process for phase II, and
Pharmaceutical
                   the sewage after treatment was discharged through the municipal pipeline network into sewage treatment
Factory
                   plants. For waste gas: currently, the company uses purchased steam and uses the boilers as backups,
                   greatly reducing exhaust gas emissions. The waste gas of the sewage treatment stations is treated by a
                   combination of rst-level spray towers, UV photoion equipment and second-level spray towers.
                   Through strict enforcement of the“Three Simultaneous”system, the“Three Wastes”were collected and
                   treated eectively. The designed total processing capacity of sewage treatment was 7,500m3/d (including
                   one plant with capacity of 5,000m3/d and one plant with capacity of 2,500m3/d), and the actual total
                   treatment amount was 3,100m 3/d. After the wastewater had reached the standard stipulated in the
                   pollutant discharge license, it would be discharged through the sewage pipeline network in the industrial
Ningxia
                   park to Xin’an Company. In 2021, the installation and use of exhaust gas collection and treatment
Pharmaceutical
                   facilities for hazardous waste stations were completed, and doramectin fermentation exhaust gas of 101
                   fermentation workshop was introduced into the specific exhaust gas treatment facility for doramectin
                   fermentation exhaust gas of 102 fermentation workshop, and a primary sedimentation tank was added
                   to the sewage treatment station to lead out exhaust gas for treatment. For details on circumstances in
                   previous years, please refer to the relevant content of the 2020 annual report of Livzon.




                                                                                                                           93
     Name of company
                                               Construction and operation of pollution preventive facilities
     or subsidiary
                     The“Three Wastes”were collected and treated effectively in strict compliance with the“Three
                     Simultaneous”system. The designed sewage treatment capacity was 3,000t/d, the treatment process of
                     “hydrolytic acidication tank + anaerobic UASB + aerobic pool + materialized treatment”was adopted,
                     the treated wastewater would be discharged through the municipal pipeline network into the sewage
                     treatment plant of Xiuwu Branch of Kangda Water Co., Ltd. ( 康 达 水 务 有 限 公 司 修 武 分 公 司 ). The
                     sewage treatment facilities were under normal operation with compliant discharge. For exhaust gas:
                     exhaust gases generated from technical process in the production zone would be collected and treated by
                     adopting two sets of processes of“water spray + active carbon and -20 ℃ condensation + water spray +
     Jiaozuo Hecheng
                     active carbon”and then discharged after reaching the required standard. For solid waste: hazardous solid
                     wastes would be stored in the hazardous waste station constructed in compliance with the requirements
                     of“Three Protections”(protection against leaks, erosion and rain) according to the requirements under
                     the (Pilot) Guidelines for Standardized Management of Hazardous Waste in Henan Province (《 河
                     南 省 危 险 废 物 规 范 化 管 理 工 作 指 南( 试 行 )》) for hazardous wastes. The company entered into a
                     hazardous waste disposal agreement with Henan Zhonghuanxin Environmental Technology Co., Ltd.
                     ( 河南中环信环保科技有限公司 ) for disposal of hazardous wastes on regular basis. Other general solid
                     wastes would be disposed of in compliance with the relevant requirements.
                         The company designed and built a sewage treatment station with a processing capacity of 200m3/d in
                         2018. The company's sewage was treated by such sewage treatment station and then entered the park's
                         sewage treatment station for secondary treatment, and finally discharged into the municipal pipeline
                         network. The company had the hazardous waste station in compliance with the requirements of“Three
     Shanghai Livzon
                         Preventions”to store hazardous waste and appointed a qualified company for compliant disposal.
                         The company's main exhaust outlets were treated with activated carbon adsorption and filtration, and
                         the activated carbon was replaced every half a year to ensure that the exhaust gas emission met the
                         standards.


 3. Environmental impact assessment of construction projects and other environmental protection administrative licensing
    √ Applicable □ N/A


     Name of company Environmental impact assessment of construction projects and other environmental protection
     or subsidiary   administrative licensing
                         The Reply to the Environmental Impact Assessment Report for the 400-ton Pharmaceutical Intermediates
                         Erythromycin Thiocyanate Project of Jiaozuo Joincare Biological Product Co.,Ltd (Jiao Huan Shen
     Jiaozuo Joincare
                         [2021] No. 29) was received on October 27, 2021. For details on circumstances in previous years, please
                         refer to the relevant content of the 2020 annual report of the Company.

     Taitai
                         There was no such project in 2021.
     Pharmaceutical

                         The“Environmental Impact Assessment Report for the Reconstruction Project of Shenzhen Haibin
                         Pharmaceutical Inc. (《深圳市海滨制药有限公司改扩建项目环境影响报告表》)”was approved on
     Haibin Pharma       November 2019; with strict enforcement of the“Three Simultaneous”system in the production process
                         and implementation of the environmental protection measures required under the environmental impact
                         assessment, the environmental protection facilities have been functioning properly.




94
                                                                                                         Annual Report
                                                                                                                 2021


Name of company Environmental impact assessment of construction projects and other environmental protection
or subsidiary   administrative licensing
                Approval of Environmental Impact Report on 20 Tonnes/Year Meropenem Pharmaceutical Intermediate
                Project (Yu Huan Jian [2005] No. 84), Opinions on Environmental Protection Inspection and Acceptance
                for 20 Tonnes/Year Meropenem Pharmaceutical Intermediate F9 Project (Yu Huan Bao Yan [2008]
                No. 89), Approval of Environmental Impact Report on 100 Tonnes/Year Meropenem Pharmaceutical
                Intermediate Expansion Project (Yu Huan Shen [2014] No. 564), Independent acceptance of Approval of
Xinxiang Haibin Environmental Impact Report on 100 Tonnes/Year Meropenem Pharmaceutical Intermediate Expansion
                Project on 24 March 2019, and Opinions of Comprehensive Supervision and Enforcement Bureau of
                High-tech Zone on Approval of Environmental Impact Report on Technical Center Expansion Project of
                Xinxiang Haibin Pharmaceutical Co., Ltd. (Xin Gao Zong Jian Zi [2020] No. 26).
                The reply to the Environmental Impact Assessment Report for the Peinan Series API Development
                Project of Xinxiang Haibin Pharmaceutical Co., Ltd (Xin Huan Shu Shen [2021] No. 24) was received.
                  The“Environmental Impact Report on the Phase III High-end Antibiotics Project of Livzon Group
                  Fuzhou Fuxing Pharmaceutical Co., Ltd.”was approved on 23 August 2021. The company strictly
                  implements the“Three Simultaneous”system and takes environmental protection measures required for
                  environmental assessment, with the environmental protection facilities under normal operation. Approval
Fuzhou Fuxing     was granted for the application of a new national pollutant discharge license on 27 December 2017 and
                  the renewal of the national pollutant discharge license was completed in December 2020. The company
                  has been discharging pollutants in strict compliance with the licensing and administrative requirements.
                  For details on circumstances in previous years, please refer to the relevant content of the 2020 annual
                  report of Livzon.
                  The“Environmental Impact Report on Current Status of Projects of Livzon Group Xinbeijiang
                  Pharmaceutical Manufacturing Inc. (《 丽 珠 集 团 新 北 江 制 药 股 份 有 限 公 司 项 目 现 状 环 境 影 响
                  报 告 书 》)”was approved and filed on 6 December 2016; with strict enforcement of the“Three
Xinbeijiang       Simultaneous”system and implementation of the environmental protection measures required under
Pharmaceutical    the environmental impact assessment, the environmental protection facilities have been functioning
                  properly. On 29 December 2017, approval was granted for the application of a new national pollutant
                  discharge license and the work for changing and renewing the pollutant discharge license was completed
                  in December 2020. The environment protection policies were strictly enforced.
                  The Environmental Impact Assessment Report on Current Status of the Product Structure and Production
                  Capacity Adjustment Project of Zhuhai FTZ Livzon Hecheng Pharmaceutical Manufacturing Co.,
                  Ltd. (《珠海保税区丽珠合成制药有限公司产品结构及产能调整项目现状环境影响评价报告》)
                  was approved in December 2016. In 2021, the environmental impact assessment of 14 new products
                  including paliperidone palmitate ( 棕 榈 酸 帕 利 呱 酮 ), aripiprazole ( 阿 立 哌 唑 ), bismuth potassium
                  citrate ( 枸 橼 酸 铋 钾 ), i.e. the“Environmental Impact Assessment Report on Technological Renovation
                  and Expansion Project of Livzon Synthetic Pharmaceutical Co., Ltd. in Zhuhai Free Trade Zone”(《 珠
                  海保税区丽珠合成制药有限公司技改扩建项目环境影响评价报告》), passed the expert review,
Livzon Hecheng
                  with approval being processed. The company strictly enforced the“Three Simultaneous”system and
                  implemented environmental protection measures as required under environmental impact assessment
                  with normal operation of the environmental protection facilities. Change of pollutant discharge license
                  was completed in December 2019. The integrated treatment on VOCs passed the“one policy for one
                  enterprise”inspection and acceptance in November 2020. On 21 December 2021, a new round of
                  voluntary clean production was inspected and approved. On 30 December 2021, the inspection and
                  acceptance of VOCs in-depth management manual was completed. In 2021, it was awarded the green
                  card enterprise of environmental credit rating by Zhuhai Municipal Ecology and Environment Bureau.




                                                                                                                          95
     Name of company Environmental impact assessment of construction projects and other environmental protection
     or subsidiary   administrative licensing
                     The company passed the environmental impact assessment on 30 June 1999 and the inspection and
                     acceptance upon completion of construction carried out by Environmental Protection Bureau of
                     Fujian Province on 5 June 2000. The company re-prepared its post-environmental impact assessment
                     report in 2019 and passed the inspection and acceptance carried out by experts on 11 June 2019. The
                     company strictly enforced the“Three Simultaneous”system and implemented the environmental
                     protection measures as required under environmental impact assessment, with normal operation of the
                     environmental protection facilities. After passing the application for a new pollutant discharge license
     Gutian Fuxing
                     from State authorities on 29 December 2017, the company strictly followed the licensing requirements
                     for emissions of pollutants and strictly complied with the administrative requirements. The procedure
                     for replacing the pollutant discharge license was completed in November 2020. In November 2021, the
                     review for initial emission right was passed, and the right will be valid for four years. In October 2021,
                     the clean production audit report was completed and passed auditing by experts, audit opinion of the
                     Ningde Environmental Science Institute was obtained, and the company is applying to the Gutian County
                     Ecology and Environment Bureau for review acceptance.
                        The Environmental Impact Report on the Technological Reform Project for the R&D Center of Livzon
                        Group Limin Pharmaceutical Manufacturing Factory (《丽珠集团利民制药厂研发中心技改项目环境
                        影响报告表》) was approved on 6 December 2019. A review expert meeting was held on 24 April 2021,
                        and independent review was completed. The Environmental Impact Report for Workshop II of Small-
     Livzon Limin       capacity Injection (《小容量注射剂二车间项目环境影响报告表》) was approved on 23 November
                        2020. On 15 September 2021, a review expert meeting was held, and independent review was completed.
                        The National Sewage Permit was updated on 22 October 2021. The“Three Simultaneous”system was
                        strictly enforced to implement the environmental protection measures required under the environmental
                        impact assessment, with normal operation of the environmental protection facilities.
                        The Environmental Impact Assessment Report on Expansion Project for Production Line of
                        Recombinant Human Chorionic Gonadotropin for Injection of Livzon Group Livzon Pharmaceutical
                        Factory ( 丽 珠 集 团 丽 珠 制 药 厂 ) was approved in March 2018; the Environmental Impact Assessment
     Livzon             Report on Expansion Project for Sewage Treatment Stations of Livzon Group Livzon Pharmaceutical
     Pharmaceutical     Factory was approved in April 2019; the Environmental Impact Assessment Report on Expansion Project
     Factory            for Production Line of lyophilized Powder Injection of Livzon Group Livzon Pharmaceutical Factory
                        was approved in November 2020. The company obtained a updated sewage permit in October 2021.
                        The company will strictly enforce the“Three-simultaneous”system to implement the environmental
                        protection measures as required by environmental assessment.
                        The environmental protection inspection for completion of doramectin expansion project was completed
                        in March 2021. In September 2021, expert review and government filing were completed for the
                        environmental impact evaluation of project work upon optimized disposal of the company's solid waste.
                        The company applied to change its pollutant discharge permit and passed the review of the Pingluo
     Ningxia
                        Branch of Shizuishan Municipal Ecology and Environment Bureau in December 2021. The company
     Pharmaceutical
                        strictly enforced the“Three Simultaneous”system to implement the environmental protection measures
                        as required by environmental assessment, and the environmental protection facilities were in normal
                        operation. For details on circumstances in previous years, please refer to the relevant content of the 2020
                        annual report of Livzon.




96
                                                                                                             Annual Report
                                                                                                                     2021


    Name of company Environmental impact assessment of construction projects and other environmental protection
    or subsidiary   administrative licensing
                    The Environmental Impact Assessment Report on Current Status of Jiaozuo Livzon Hecheng
                    Pharmaceutical Manufacturing Co., Ltd. (《焦作丽珠合成制药有限公司现状环境影响评估报告》)
                    was approved and filed on 15 December 2016, the“Three Simultaneous”system was strictly enforced,
                    the environmental protection measures as required by environmental assessment were implemented
    Jiaozuo Hecheng and the environmental protection facilities were in normal operation. The application for the national
                    pollutant discharge license was completed in December 2020, the environmental protection policies
                    were strictly enforced and various management measures were implemented. In 2021, Jiaozuo Livzon
                    Hecheng Pharmaceutical Manufacturing Co., Ltd. prepared the implementation plan of“one factory, one
                    policy”for emergency emission reduction in response to heavy pollution weather from 2021 to 2022.
                       The company passed the environmental assessment review of the Leuprorelin Acetate Microspheres for
                       Injection Industrialization Project (《注射用醋酸亮丙瑞林微球产业化项目》) on 11 October 2010,
                       obtained the approval for the Environmental Impact Report on Supporting Engineering and Laboratory
                       Projects of Shanghai Livzon Pharmaceutical Manufacturing Co., Ltd. (《上海丽珠制药有限公司配套工
    Shanghai Livzon    程及实验室项目环境影响报告》) on 10 January 2020, and completed the construction and passed the
                       acceptance inspection in September 2020. The company strictly implements the“Three Simultaneous”
                       system and take environmental protection measures required for environmental assessment, with the
                       environmental protection facilities under normal operation. In July 2021, the change of national pollutant
                       discharge license was completed.


4. Environmental emergency contingency plan
   √ Applicable □ N/A


    Name of company
                                                     Environmental emergency contingency plan
    or subsidiary
                       Revision of the environmental emergency contingency plan of Jiaozuo Joincare was completed in early
                       April 2019 and was led with the Ecological Environment Bureau of Jiaozuo City on 16 April 2019.
    Jiaozuo Joincare
                       Revision of the environmental emergency contingency plan for hazardous waste pollution accident of
                       Jiaozuo Joincare was completed in December 2020.
    Taitai
                       Review ling was completed in July 2020.
    Pharmaceutical
                       The Environmental Emergency Contingency Plan was revised and recorded (record number: 440308-
    Haibin Pharma      2020-0029M). Trainings and drills on emergency responses were provided for employees to improve the
                       capability of the Company for dealing with environmental emergencies.
                       Environmental Emergency Contingency Plan of Xinxiiang Haibin Pharmaceutical Co., Ltd. was
    Xinxiang Haibin    filed with the Ecological Environment Bureau on 14 February 2019 with the file reference number
                       4107712019001.




                                                                                                                             97
     Name of company
                                                      Environmental emergency contingency plan
     or subsidiary
                       Pursuant to relevant regulations and requirements, the“Environmental Emergency Contingency Plan of
                       Livzon Group Fuzhou Fuxing Pharmaceutical Co., Ltd. (《丽珠集团福州福兴医药有限公司突发环境
                       事 件 应 急 预 案 》)”was prepared based on the principles of“Focusing on Prevention, Aiming at Self-
                       help, Centralized Command, Division of Responsibility”, which was approved on 1 November 2019
                       with the le reference number 350181-2019-039-M.
                       After environmental emergency incidents occur, immediate, quick, effective and orderly emergency
     Fuzhou Fuxing     rescue actions will be taken to control and prevent accidents and the spread of contamination, protect
                       the surrounding environment effectively and ensure the personal life and property safety of all
                       employees, the company and the nearby communities. In accordance with the contents and requirements
                       of such plan, the company provides trainings and drills for its employees to get them well-prepared
                       for environmental emergency incidents, so that rescue actions could be taken in a timely manner
                       and incidents could be controlled effectively in a short period of time in case of any environmental
                       emergency incidents. In June 2021, the RTO power failure emergency drill was conducted.
                       Based on the principles of“Focusing on Prevention, On-alert all the time; Management by
                       Classication, Response by Tiers; Cooperation among Departments, Responsibility by Levels; Scientic
                       Prevention and Ecient Disposal”, Xinbeijiang Pharmaceutical entered into the issued“Environmental
                       Emergency Contingency Plan of Livzon Group Xinbeijiang Pharmaceutical Manufacturing Inc. (《 丽
                       珠 集 团 新 北 江 制 药 股 份 有 限 公 司 突 发 环 境 事 件 应 急 预 案 》)”(File No. 441802-2021-0162-H)
     Xinbeijiang
                       again on 30 September 2021, which has been verified and filed by the Qingyuan Municipal Ecology
     Pharmaceutical
                       and Environment Bureau on 22 October 2021. The company conducted internal exercises regularly to
                       identify environmental factors and sources of hazards, as well as drills on the emergency contingency
                       plan. The environmental emergency contingency drill was conducted in June 2021 to improve the
                       operability thereof, enhance the performance level of the emergency rescue staff, responsiveness of the
                       rescue team as well as coordination and collaboration of dierent tasks.
                       Pursuant to relevant provisions and requirements, the Environmental Emergency Contingency Plan of
                       Zhuhai FTZ Livzon Hecheng Pharmaceutical Manufacturing Co., Ltd. (《 珠 海 保 税 区 丽 珠 合 成 制 药
                       有 限 公 司 突 发 环 境 事 件 应 急 预 案 》) was prepared based on the principles of“Focus on Prevention,
                       Aim at Self-rescue, Centralized Command, and Division of Responsibility ( 预 防 为 主、 自 救 为
                       主、 统 一 指 挥、 分 工 负 责 )”, which has been approved for ling and formally announced with le
     Livzon Hecheng
                       reference number 440462-2019-001-M. Trainings on emergency events and disposal measures were
                       held regularly for employees to enable implementation of safety measures in a timely, fast, effective
                       and orderly manner to control and prevent the worsening of condition and pollution when encountering
                       any occurrence of environmental emergency cases, so as to alleviate or eliminate the consequences
                       eectively and resume orderly production as soon as possible.




98
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                                                                                                                 2021


Name of company
                                                Environmental emergency contingency plan
or subsidiary
                  Pursuant to relevant provisions and requirements, the Environmental Emergency Contingency Plan of
                  Gutian Fuxing Pharmaceutical Co., Ltd. (《古田福兴医药有限公司突发环境事件应急预案》) was
                  prepared based on the principles of“Focus on Prevention, Aim at Self-rescue, Centralised Command and
                  Division of Responsibility ( 预防为主、自救为主、统一指挥、分工负责 )”. The contingency plan
                  was approved in May 2017 with the le reference number 352200-2017-005-L. The second amendment
                  of the contingency plan was made in June 2020, which passed expert review and completed filing, with
                  the ling number 350922-2020-002-M.
                  According to the plan, after environmental emergency incidents occur, immediate, quick, effective
Gutian Fuxing
                  and orderly emergency rescue actions will be taken to control and prevent accidents and the spread of
                  contamination, protect the surrounding environment eectively and ensure the personal life and property
                  safety of all employees, the company and the nearby communities. In accordance with the contents and
                  requirements of the plan, the company provides trainings and drills for its employees. On 9 September
                  2021, the company carried out an ammonia leakage emergency drill. The company is well-prepared
                  for environmental emergency incidents, so that rescue actions could be taken in a timely manner
                  and incidents could be controlled effectively in a short period of time in case of any environmental
                  emergency incidents.
                  The principles of occupational health and safe environment administrative system were followed,
                  including occupational protection to ensure health, risk control to ensure safety, prevention and
                  control of pollution to protect the environment, and compliance with discipline and law for continuous
                  improvement. Identication of environmental factors was performed seriously and preventive measures
                  were adopted for significant environmental factors, while the governance of the“Three Wastes”was
                  strengthened to enhance the ability of control over the“Three Wastes”and ensure that the discharge of
                  the“Three Wastes”had reached the discharge standards. The Environmental Emergency Contingency
                  Plan of Livzon Group Limin Pharmaceutical Manufacturing Factory (《丽珠集团利民制药厂突发环境
Livzon Limin
                  事件应急预案》) was prepared in accordance with the criteria of the environmental management system
                  and the occupational health and safety administrative system. The plan was issued in May 2021(File
                  No. 440203-2021-009-L).According to the contingency plan, an environmental accident emergency
                  drill was conducted on 24 September 2021, and a specific drill summary was made. Identification of
                  environmental factors and sources of hazards and drills for emergency were conducted internally in the
                  company on regular basis to improve the operability of the contingency plan, enhance the performance
                  level of the emergency rescue staff, responsiveness of the rescue team as well as coordination and
                  collaboration of dierent tasks.
                  Pursuant to relevant regulations and requirements, the Environmental Emergency Contingency Plan of
                  Livzon Group Livzon Pharmaceutical Factory (《丽珠集团丽珠制药厂突发环境事件应急预案》)
Livzon
                  was updated by the company in 2021, and has been approved for ling approval and announced, with the
Pharmaceutical
                  File No. 440404-2021-0212-L. In October 2021, the company conducted an emergency drill for alcohol
Factory
                  leakage in the dangerous goods warehouse, to enhance emergency response capabilities of sta, so as to
                  alleviate or eliminate the consequences eectively.
                  The Environmental Emergency Contingency Plan of Livzon Group (Ningxia) Pharmaceutical
                  Manufacturing Co., Ltd. (《 丽 珠 集 团( 宁 夏 ) 制 药 有 限 公 司 突 发 环 境 事 件 应 急 预 案 》) was
                  verified, filed and issued in May 2019 (filing reference number: 640221-2019-005-II). Identification of
                  environmental factors and sources of hazards and drills for emergency were conducted internally in the
Ningxia
                  company on regular basis to improve the operability of the contingency plan, enhance the performance
Pharmaceutical
                  level of the emergency rescue sta, and enhance the responsiveness and coordination of the rescue team
                  in terms of integrated coordination and collaboration capabilities. Reamendment of the Environmental
                  Emergency Contingency Plan was amended in May 2021, and has passed expert review and has been
                  reviewed and led by government environmental department in August 2021.




                                                                                                                         99
      Name of company
                                                       Environmental emergency contingency plan
      or subsidiary
                         The Environmental Emergency Contingency Plan of Jiaozuo Livzon Hecheng Pharmaceutical
                         Manufacturing Co., Ltd. (《焦作丽珠合成制药有限公司突发环境事件应急预案》) was prepared
                         in accordance with the relevant provisions and requirements and based on the principles of“Focusing
                         on Prevention, On-alert all the time; Management by Classification, Response by Tiers, Cooperation
                         among Departments, Responsibility by Levels; Scientific Prevention and Efficient Disposal”. The
                         contingency plan was approved for announcement and filing in April 2021 (filing reference number:
                         4108042018005L). The Hazardous Waste Environmental Pollution Emergency Contingency Plan of
                         Jiaozuo Livzon Hecheng Pharmaceutical Manufacturing Co., Ltd. (《 焦 作 丽 珠 合 成 制 药 有 限 公 司
                         危 险 废 物 环 境 污 染 事 故 应 急 预 案 》) was compiled and was approved for ling in January 2018.
                         Identication of environmental factors and sources of hazards and drills for emergency were conducted
      Jiaozuo Hecheng    internally in the company on regular basis to improve the operability of the contingency plan, enhance
                         the performance level of the emergency rescue sta, and enhance the responsiveness and coordination of
                         the rescue team in terms of integrated coordination and collaboration capabilities. The company carried
                         out trainings on the Standard Operating Procedure for Acid Mist Purification Towers and the Standard
                         Operating Procedure for Hazardous Waste Storage Pollutants in April 2021 and June 2021, respectively,
                         according to the relevant requirements of the Hazardous Waste Environmental Pollution Emergency
                         Contingency Plan of Jiaozuo Livzon Hecheng Pharmaceutical Manufacturing Co., Ltd. (《 焦 作 丽 珠 合
                         成制药有限公司危险废物环境污染事故应急预案》). In November 2021, the“Operation Regulations
                         for Exhaust Gas UV Photolysis Equipment”and the“Spray Towers Operation Regulations”were added,
                         and training was carried out on the operation regulations for exhaust gas UV photolysis equipment and
                         spray tower operation regulations to enhance the environmental protection knowledge of sta.
                         In January 2019, the Environmental Emergency Contingency Plan of Shanghai Livzon Pharmaceutical
                         Manufacturing Co., Ltd. (《 上 海 丽 珠 制 药 有 限 公 司 突 发 环 境 事 件 应 急 预 案 》) was led by the
      Shanghai Livzon
                         company, with the File No. 02-310115-2019-027-L. The company conducts drills and reviews of the plan
                         every year to improve its emergency response capabilities through regular training on the plan.


 5. Environmental self-monitoring program
    √ Applicable □ N/A


      Name of company
                                                         Environmental self-monitoring program
      or subsidiary
                         As required by the self-monitoring program for pollutant discharge licenses, Jiaozuo Joincare developed
                         the 2021 Self-monitoring Program at the beginning of 2021 and carried out self-monitoring according to
      Jiaozuo Joincare
                         the program. As at 31 December 2021, Jiaozuo Joincare has completed the self-monitoring for the full
                         year.
                         Wastewater was monitored once a quarter; boiler exhaust gas and plant boundary noise were monitored
      Taitai             once a year; exhaust gases generated from technical process was monitored once half a year; online
      Pharmaceutical     monitoring facilities of wastewater and boiler exhaust gas were additionally installed and functioning
                         well.
                         A third party is entrusted to conduct regular monitoring strictly in compliance with the relevant national
                         laws and regulations and local requirements and ensure the accuracy, validity and authenticity of the
      Haibin Pharma      monitoring data. Online wastewater monitoring equipment was installed and connected to environmental
                         monitoring stations at municipal and district levels in accordance with environmental monitoring
                         technical standards. Data was promptly uploaded on the national monitoring platform.
                         Exhaust gas and wastewater were monitored quarterly by the third party in accordance with the new
      Xinxiang Haibin
                         version of pollutant discharge license.




100
                                                                                                        Annual Report
                                                                                                                2021


Name of company
                                                  Environmental self-monitoring program
or subsidiary
                  According to the relevant requirements of the“Measures for Self-Monitoring and Information Disclosure
                  by Enterprises subject to Intensive Monitoring and Control of the State (Trial Implementation) (《国家重
                  点监控企业自行监测及信息公开办公(试行)》)”and the“Technical Guidelines for Self-Monitoring
                  by Pollution Discharge Enterprises in the Fermentation Pharmaceutical Industry (HJ882-2017) (《 排
                  污 单 位 自 行 监 测 技 术 指 南 发 酵 类 制 药 工 业 (HJ882-2017)》)”, the company has completed the
                  establishment of the self-monitoring program based on its own situation in a timely manner and
                  made the program available to the public after being examined by and filed with Fuqing Environment
                  Protection Bureau and Fuzhou Environment Protection Bureau. The analysis methods of the monitoring
                  program comply with the national environmental monitoring technical standards and methods; the
Fuzhou Fuxing
                  monitoring and analysis instruments have been examined and calibrated in strict compliance with the
                  relevant national requirements; the automated monitoring equipment has been installed in accordance
                  with the requirement of environmental assessment technical standards, which are connected to relevant
                  environmental protection authorities and have passed the inspection and acceptance of the relevant
                  environmental protection authorities. The automated monitoring equipment has been functioning
                  properly and the monitoring information is accurate, valid and authentic. In 2021, the work on leakage
                  detection and repair (LDAR) of volatile organic compounds (VOCs) was done on two occasions. The
                  soil and groundwater testing was completed in July 2021. Information publicity website: http://wryfb.
                  fjemc.org.cn.
                  According to the relevant requirements of the“Measures for Self-Monitoring and Information Disclosure
                  by Enterprises subject to Intensive Monitoring and Control of the State (Trial Implementation) (《 国 家
                  重点监控企业自行监测及信息公开办法(试行)》)”, the company has completed the establishment
                  of the self-monitoring program based on its own situation in a timely manner and made the program
                  available to the public after being examined by and led with Qingyuan Environment Protection Bureau.
                  The analysis methods of the monitoring program comply with the national environmental monitoring
                  technical standards and methods; the monitoring and analysis instruments have been examined and
                  calibrated in strict compliance with the relevant national requirements. The automated monitoring
Xinbeijiang
                  equipment for waste water (COD, ammonia nitrogen, pH, flow) and waste gases (non-methane
Pharmaceutical
                  hydrocarbons) has been installed in accordance with the requirement of environmental assessment
                  technical standards, and the connection between online information and national development platform
                  and Qingyuan municipal platform has been completed. Online monitoring equipment for waste water has
                  passed the inspection and acceptance of relevant environmental protection authorities. The automated
                  monitoring equipment has been functioning properly and the monitoring information is accurate, valid
                  and authentic. In accordance with the requirements of the specication, a third party is hired to conduct
                  LADR testing and repairs every six months for workshops that use VOCs. On 28 September 2021, the
                  TOC testing for the import and export of cooling towers was completed.
                  Through self-monitoring, the requirements under the Technical Standards for Application and Issuance
                  of Pollutant Discharge License for the Pharmaceutical Industry- Active Pharmaceutical Ingredient
                  Manufacturing (HJ858.1-2017) (《排污许可证申请与核发技术规范制药工业 - 原料药制造 (HJ858.1-
                  2017)》) were strictly implemented, and the verication and calibration of monitoring analyzing devices
Livzon Hecheng    were carried out in strict compliance with relevant provisions. Automated monitoring equipment was
                  installed according to the requirements of technical standards for environmental detection, while online
                  monitoring equipment for COD, ammonia nitrogen and PH level and online monitoring equipment for
                  non-methane hydrocarbons were installed and connected with the national development platform as
                  required.




                                                                                                                      101
      Name of company
                                                        Environmental self-monitoring program
      or subsidiary
                        According to the relevant requirements of the“Measures for Self-Monitoring and Information Disclosure
                        by Enterprises subject to Intensive Monitoring and Control of the State (Trial Implementation) (《 国
                        家 重 点 监 控 监 控 企 业 自 行 监 测 及 信 息 公 开 办 法( 试 行 )》)”, the company has completed the
                        establishment of the self-monitoring program based on its own situation in a timely manner and
                        made the program available to the public after being examined by and filed with Ningde environment
                        protection authority and Gutian County protection authority. The analysis methods of the monitoring
                        program comply with the national environmental monitoring technical standards and methods; the
      Gutian Fuxing     monitoring and analysis instruments have been examined and calibrated in strict compliance with the
                        relevant national requirements; the automated monitoring equipment has been installed in accordance
                        with the requirements of environmental assessment technical standards, connected to the network of
                        competent environmental protection authorities and passed the acceptance inspection conducted by
                        the competent environmental protection authorities. The automated monitoring equipment was sound,
                        and the monitoring information was accurate, valid and authentic. In 2021, a qualified third party was
                        engaged on two occasions to complete the leakage detection and repair (LDAR) work of volatile organic
                        compounds and a report was obtained. Information publicity website: http://wryfb.fjemc.org.cn.
                        An entity with national qualification on inspection was engaged to conduct monitoring strictly in
                        compliance with the relevant national laws and regulations and standards. By considering its own
                        specific conditions, the company appointed the inspection party to carry out water pollutant detection
                        monitoring every quarter and boiler exhaust gas monitoring every month, each time the monitoring
                        would be conducted strictly in compliance with the relevant national requirements to ensure the
      Livzon Limin      accuracy, validity and authenticity of the monitoring data. The installation and commissioning of
                        online monitoring equipment for COD, ammonia nitrogen was completed and began to run officially in
                        December 2020, and COD and ammonia nitrogen were monitored every 2 hours. Online data should be
                        completed and filed to the Shaoguan Municipal Ecology and Environmental Bureau on a timely basis,
                        and the relevant data would be announced to the public after being reviewed by and filing with the
                        Shaoguan Municipal Ecology and Environmental Bureau.
                        Inspection party with national qualification on inspection was engaged to conduct monitoring strictly
                        in compliance with the relevant national laws and regulations and standards. By considering its own
      Livzon            specific conditions, the company appointed the inspection party to carry out monitoring on sewage and
      Pharmaceutical    waste gas every month, each time the monitoring would be conducted strictly in compliance with the
      Factory           relevant national requirements to ensure the accuracy, validity and authenticity of the monitoring data.
                        The installation and commissioning of the online sewage monitoring equipment was completed and it
                        was put into use at the beginning of 2021.
                        The company formulated the self-monitoring program for 2021, which was reviewed by and filed
                        with the Ecological Environment Bureau of Shizuishan City. Monthly and quarterly monitoring was
                        carried out strictly in accordance with the requirements of the program, which focused primarily on
                        organized exhaust gas emission, exhaust gas emission from boiler, waste water discharge, underground
                        water, soil, plant boundary unorganized environmental air, noise and recycled water TOC, and volatile
                        organic matter leak detection and repair (LDAR) work was carried out. The monitoring results would
      Ningxia           be announced to the public through the System of National Pollution Sources Monitoring Information
      Pharmaceutical    Management and Sharing Platform (《全国污染源监测信息管理与共享平台系统》) and the System
                        of Self-monitoring Information Open Platform for Enterprises in Shizuishan (《 石 嘴 山 市 企 业 自 行 监
                        测 信 息 公 开 平 台 系 统 》). The automated monitoring equipment was connected to the network of the
                        competent environmental protection authority and passed the inspection conducted by the competent
                        environmental protection authority. The automated monitoring equipment was sound, and the monitoring
                        information was accurate, valid and authentic. In the first half of 2021, the RTO exhaust VOCs online
                        monitoring equipment was installed and put into use, and passed government inspection in August 2021.




102
                                                                                                               Annual Report
                                                                                                                       2021


    Name of company
                                                        Environmental self-monitoring program
    or subsidiary
                        According to the relevant requirements of the Measures for Self-Monitoring and Information Disclosure
                        by the Enterprises subject to Intensive Monitoring and Control of the State (Trial Implementation) (《 国
                        家 重 点 监 控 企 业 自 行 监 测 及 信 息 公 开 办 法( 试 行 )》), the company implemented and completed
                        the self-monitoring program based on its own situation in a timely manner and made the program
                        available to the public after being examined by and filed with relevant competent environmental
                        protection authorities. The analysis methods of the monitoring program comply with the national
                        environmental monitoring technical standards and methods; the monitoring and analysis instruments
                        have been examined and calibrated in strict compliance with the relevant national requirements; the
    Jiaozuo Hecheng
                        automated monitoring equipment has been installed in accordance with the requirement of environmental
                        assessment technical standards. In 2018, the online water quality monitoring equipment had passed
                        the inspection and acceptance conducted by the competent environmental protection authorities and
                        the connection between the online data and the municipal platform of Jiaozuo City was completed;
                        the Internet Private Line Access Clustering Protocol was entered into in November 2021. The leak
                        detection and repair (LDAR) of volatile organic compounds was completed according to plan in 2021.
                        The automated monitoring equipment was under normal operation and the data was accurate, valid and
                        authentic.
                        In accordance with the General Rules for the Self-Monitoring Technical Guidelines for Pollutant
                        Discharge Units (《排污单位自行监测技术指南总则》) (HJ 819-2017) and the relevant requirements
                        (including those on pollution discharge license), the company organized self-monitoring and information
    Shanghai Livzon     disclosure of the pollutants it has discharged, and formulated the Self-monitoring Program. In 2021, the
                        company monitors main exhaust gas outlets once a month, common discharge outlets once half a year,
                        noise once every quarter and sewage once a month. The monitoring items and frequency shall meet the
                        requirements of the pollutant discharge license.


6. Administrative punishments imposed for environmental issues during the Reporting Period
   □ Applicable √ N/A

7. Other environmental information to be disclosed
   □ Applicable √ N/A


(II) Statement on environmental protection conditions of companies except for key pollutant discharge units
    √ Applicable □ N/A

   The remaining subsidiaries of the Company strictly and thoroughly implemented and obeyed the Environmental Protection
   Law of the People's Republic of China, Cleaner Production Law of the People's Republic of China and other environmental
   protection and safe production laws and regulations, constantly increased investment in environmental protection, continuously
   invested in energy conservation and consumption reduction projects, actively promoted cleaner production, improved
   comprehensive utilization eciency of resources, and reduced and avoided pollutants so as to ensure sound mind and body of
   employees and try to realize coordination of economic, environmental and social benets and sustainable development.

1. Administrative punishments imposed for environmental issues
   □ Applicable √ N/A

2. Refer to other environmental information disclosed by key pollutant discharge units
   □ Applicable √ N/A

3. Reasons for non-disclosure of other environmental information
   □ Applicable √ N/A




                                                                                                                              103
(III) Relevant information contributing to ecological protection, pollution prevention and control, and fulfillment of
      environmental responsibilities
      √ Applicable □ N/A


      Name of company          Relevant information contributing to ecological protection, pollution prevention and control,
      or subsidiary                                 and fulllment of environmental responsibilities
                         The company completed verication of carbon emissions and the external audit on the energy system. In
      Jiaozuo Joincare   the evaluation of green development of the pharmaceutical industry in Henan Province, it ranked second
                         among the industrial peers. LDAR leak detection and repair was conducted twice.
                         Creation of environmental safety standardization, management of hazardous waste standardization, on-
                         site inspection, cooperation with the Ecological Environment Department or its entrusted third-party
      Taitai
                         evaluation agency to carry out the safety evaluation and inspection of corporate environmental facilities,
      Pharmaceutical
                         operating systems and online inspection systems, prompt rectification of hidden hazards proposed were
                         carried out as required by the Municipal Ecological Environment Department.
                         The company promoted LDAR detection, to timely repair leakage points and reduce unorganized
      Haibin Pharma
                         emission of VOCs.
                         The company completed verication of carbon emissions, and in the evaluation of green development of
      Xinxiang Haibin
                         the pharmaceutical industry in Henan Province, it ranked fourth among the industrial peers.
                         All waste water from production was collected and sent to the waste water treatment station for
      Joincare Haibin    treatment, and then sent back to the cooling tower for reuse, so as to realize“zero”discharge of waste
                         water.
                         Two LDARs in the rst half and second half of the year, detection of hidden hazards in soil, detection of
                         soil, audit of energy system, verification of greenhouse gas emission, and application for the certificate
      Fuzhou Fuxing
                         of provincial green factory were completed. In the environmental credit evaluation completed, the
                         company was rated as an environmentally credible enterprise.
                         LDAR was completed; unorganized emission of VOCs was reduced; certification audit of energy
                         management system was completed; a series of waste gas and noise control and improvement measures,
                         such as reconstruction of certain sewage tanks, installation of noise segregation wall on the cooling
      Xinbeijiang        tower, and installation of the inlet muffler on the boiler, were taken to effectively reduce impacts of
      Pharmaceutical     waste gas emission and noise on the surrounding environment; sealing around the reverse hanging
                         membrane of the pretreatment tank at the waste water treatment station was reinforced to reduce
                         unorganized odor dispersion in surrounding areas; the RTO operation processing level was improved;
                         and the VOCs processing eciency was raised to 98%, eectively reducing VOCs emission.
                         LDAR was completed; unorganized emission of organic gas was reduced; hazardous waste was entrusted
                         to qualied units for treatment with compliance treatment rate of 100%; and tail gas treatment facilities
      Livzon Hecheng
                         were added at gas collection station by the QC Testing and Technical Development Department. The
                         self-monitoring plan was completed and environmental responsibilities were fullled as required.
                         LDAR was completed; cover and sealing were added to sewage treatment regulating pool; waste gas
                         was collected and treated so as to avoid odor spillover; HV frame was replaced in the sewage treatment
                         workshop; water content of sludge was reduced; total volume of sludge was reduced; sludge generated
      Gutian Fuxing      was entrusted to qualified units for treatment; and the entrusted testing of waste water, waste gas, soil
                         and groundwater in 2021 was completed, with the results showing they were all up to the standards.
                         Hazardous waste was entrusted to qualified companies for compliant treatment to reduce the risk of
                         environmental pollution.
                         Solid preparations and steam equipment in high capacity workshop were renovated; steam usage was
                         reduced; locations of dierent drugs in the overhead cabin and TCM cabin were adjusted; storage energy
      Livzon Limin
                         consumption of the two cabins was reduced; three idle water pumps of the factory were used; post-
                         treated waste water was used for watering owers, trees and grass in the factory in three lines.




104
                                                                                                                Annual Report
                                                                                                                        2021


     Name of company           Relevant information contributing to ecological protection, pollution prevention and control,
     or subsidiary                                  and fulllment of environmental responsibilities
                        Installation and debugging of online monitoring equipment were completed; qualified third party was
     Livzon             entrusted to detect waste water and waste gas; compliant treatment of hazardous wastes was made; the
     Pharmaceutical     risk of environmental pollution was reduced. Environmental impact assessment was conducted for new
     Factory            workshops as required. The facilities at the waste water treatment station were renovated to ensure the
                        sewage treatment meets the national standards, and at the same time, improve the treatment eciency.
                        LDAR was completed; field check of“one policy for one enterprise”for corporate VOCs governance
                        was carried out in cooperation with leaders and experts of the Municipal Environmental Protection
                        Department; installation of online monitoring equipment for RTO exhaust and VOCs was completed;
                        installation of treatment facilities for exhaust gas from hazardous waste stations, primary sedimentation
     Ningxia            tank at the sewage treatment station and 101 doramectin fermentation workshop, and installation of
     Pharmaceutical     the dust collection and treatment facilities for the boiler coal conveying system were completed. The
                        environmental protection inspection for completion of doramectin expansion project was completed, and
                        the evaluation of project work upon optimized disposal of the company's solid waste was carried out.
                        The amendment of the Environmental Emergency Contingency Plan was completed. The monthly and
                        quarterly self-monitoring was completed as required.
                        Automatic construction was carried out; LDAR was completed; green development evaluation
                        of the pharmaceutical industry in Henan Province was completed; the result of being No. 8 in the
                        pharmaceutical industry of Henan Province was achieved; treated waste gas was replaced to ensure
                        the treatment effect; hazardous waste was entrusted to qualified units for treatment with compliance
     Jiaozuo Hecheng
                        treatment rate of 100%; waste gas was entrusted to qualified third party for testing; the facilities of the
                        waste water system were entrusted to qualified third party for maintenance; the“one policy for one
                        enterprise”as advocated by the Municipal Environmental Protection Bureau for emergency emission
                        reduction in heavily polluted weather was implemented.
                        The company discharged pollutants in strict compliance with standards set out in the pollution discharge
                        license obtained, developed the annual self-monitoring program for pollution discharge at the beginning
                        of 2021 and implemented it, and successfully passed the semi-annual and annual review of corporate
                        pollution discharge by the third party entrusted by government departments. It also completed the annual
                        report on compliance with the pollution discharge license without violation of laws and regulations.
                        Meanwhile, the company further strengthened the daily monitoring of operation of waste gas treatment
     Shanghai Livzon
                        facilities and waste water treatment stations and ensured the effective operation of equipment and
                        facilities. The company developed the Plan on Comprehensive VOCs Treatment and Emission Reduction
                        in General Enterprises in accordance with the Notice on Comprehensive Treatment of Volatile Organic
                        Compounds in Key Industries in the City issued by Shanghai Ecological Environment Department, and
                        used bromogeramine (benzalkonium bromide) solution to replace part of ethanol for disinfection, so as to
                        meet the VOCs emission targets.


(IV) Measures for carbon emission reduction and effect during the Reporting Period
    √ Applicable □ N/A


     Name of company
                                     Measures for carbon emission reduction and eect during the Reporting Period
     or subsidiary
                        In the fermentation workshop, the control parameters of fermentation tank consumption were optimized
                        to reduce steam flow and cut steam consumption; the stirring motor of fermentation tanks was changed
                        from fixed frequency to variable frequency to realize real-time control of the rotation speed so as to
     Jiaozuo Joincare
                        reduce power consumption and carbon emission. In the refining workshop, plate heat exchangers were
                        installed in front of the desorption tanks to stabilize the temperature of water supply by physical means,
                        so as to save one compressor on the refrigerator from being used and reduce power consumption.




                                                                                                                               105
      Name of company
                                     Measures for carbon emission reduction and eect during the Reporting Period
      or subsidiary
                        Lighting facilities in the park were replaced with“energy-saving lamps”in response to the call of the
                        Municipal Government, producing prominent energy-saving eect; the high-power motor in the factory
                        was replaced with the efficient energy-saving motor in accordance with energy-saving requirements of
      Taitai
                        the government and frequency conversion devices were installed to maximize energy conservation. The
      Pharmaceutical
                        ecient low-nitrogen boiler was replaced in response to the call of“Green Shenzhen”; employees were
                        organized to learn energy conservation knowledge so as to achieve energy conservation and emission
                        reduction in routine work by turning o lamps and machines timely.
                        In 2021, the old cooling tower was replaced with a new efficient one, saving about 5,976 yuan and
                        reducing carbon dioxide emission of about 9.5 tons annually. In 2021, the pump motor at the water pump
                        house was replaced with an energy-saving one, saving about 14,172 yuan and reducing carbon dioxide
      Haibin Pharma
                        emission of about 22.4 tons annually; in the same year, the waste water treatment blower was replaced
                        with an air suspension blower, saving about 90,000 yuan and reducing carbon dioxide emission of about
                        136.6 tons annually.
                        The company invested 3 million yuan to replace the leaky reciprocating vacuum pumps with screw
      Xinxiang Haibin
                        vacuum pumps and liquid ring pumps.
                        The company purchased energy-saving and power-saving equipment meeting the new standards,
                        developed energy-saving habits and thinking, reduced the use of natural gas in boilers, increased the
      Joincare Haibin
                        frequency of facility maintenance and pipeline inspection, adopted eective heat preservation measures,
                        and encouraged use of pure electric cars for traveling to save fuel.
                        The company introduced PV power generation to reduce power consumption. Energy-saving renovation
                        of high energy consumption pumps were carried out, effectively reducing energy consumption.
      Fuzhou Fuxing
                        The company vigorously publicized energy conservation and consumption reduction, and called on
                        employees to promptly turn o lamps, air conditioners and computers in routine work.
                        Certain cooling towers were renovated; fans of cooling towers were driven by hydrodynamic kinetic
                        energy rather than motors, achieving the same cooling effect while reducing power consumption;
                        80m3 air compressor was renovated and added a heat exchanger so that boiler soft water was preheated
                        through running heat of air compressor and boiler inlet temperature was raised, effectively reducing the
      Xinbeijiang
                        consumption of natural gas ; inner wall of MVR equipment was cleaned by a professional third party,
      Pharmaceutical
                        making the evaporation rate of sugar water for MVR equipment increase by approximately 40% so as
                        to effectively reduce the run time of MVR equipment and greatly reduce power consumption; the old
                        boilers with high energy consumption and high maintenance costs were replaced with new ones, reducing
                        the average steam consumption per ton by1.06m3 natural gas.
                        Water cooling units were maintained and renovated so as to use energy in a more reasonable manner;
                        power consumption for production was saved through a more reasonable production scheduling of the
                        Production Department; the natural gas was used as the fuel for the canteen and boiler of the company;
                        the Roots fans for sewage treatment at the Environmental Protection Center were replaced with magnetic
      Livzon Hecheng    levitation fans with a relative energy saving rate of 30%, saving about 100,000 KWH of power annually.
                        All employees in the factory were called on to save electricity by turning off lamps and air conditioners
                        after work, and limit the minimum temperature of air conditioners; green travel was promoted;
                        employees were encouraged to take public transportation for business trip; commuting buses were
                        provided for employees.
                        Four sets of air compressors and a set of water cooling unit were replaced to reduce power consumption;
      Gutian Fuxing     all employees were called on to“save every drop of water and every kilowatt hour”by turning o lamps
                        and shutting down equipment after work.




106
                                                                                                            Annual Report
                                                                                                                    2021


Name of company
                               Measures for carbon emission reduction and eect during the Reporting Period
or subsidiary
                  In the solid agent workshop, the set values of temperature and humidity of the air conditioning system
                  were appropriately adjusted (within the reference range) to be as close as possible to the values of the
                  ambient temperature and humidity to reduce steam consumption; the large - capacity workshops were
                  renovated to save steam; the energy consumption was reduced by the QC Department through control of
Livzon Limin
                  the number of compressors of the air conditioning unit in service and parameter setting, and intermittent
                  use of the biological test room; the total energy consumption of warehouses was reduced by the Supply
                  Chain Department through reasonably relocating and merging warehouses of Chinese medicinal
                  materials on eight oors and construction of cool warehouses according to requirements of GSP.
                  Incandescent light bulbs were replaced with LED lamps to reduce power consumption. PV inverter
                  cabinets and roof PV modules were renovated, which improved PV power generation efficiency
Livzon
                  and could save about 600,000 kilowatts per year. Outsourced steam was introduced to reduce boiler
Pharmaceutical
                  combustion and save energy. Functional departments were required to further tighten energy conservation
Factory
                  management, and encourage employees to turn off lights and machines during the lunch break, or when
                  they leave their post, so as to reduce power consumption.
                  Two 1500m/h cooling water towers were newly installed to reduce the consumption of primary water.
                  The waste condensate water produced by MVR equipment was used to replace the primary water for
                  ceramic membrane cleaning. Part of phenylalanine spent activated carbon was reused to reduce the spent
Ningxia           activated carbon generated. Phenylalanine concentration system was planned to be renovated, pursuant
Pharmaceutical    to which, the original triple effect thickening system was replaced with MVR thickening system, thus
                  reducing energy consumption by 50%. The boiler system was overhauled and maintained regularly so as
                  to ensure ecient operation of boiler body and desulfurization and dust removal facilities. Consumption
                  of outsourced steam was increased to reduce coal consumption.
                  The production process was promptly adjusted in coordination with the workshop; activated carbon
                  in the activated carbon adsorption plant was replaced so as to try to emit organic waste gas in stable
                  concentration; steam condensate was changed for recycling so as to reduce carbon emission. Packaging
                  equipment of the company was changed to automatic packaging. Energy conservation and consumption
                  reduction were vigorously publicized in the company; all employees were called on to“save every
                  drop of water and every kilowatt hour”. Workshop paint was put unified management, to avoid waste;
Jiaozuo Hecheng
                  a view mirror was added behind the steam trap valve to observe steam loss; unqualified water in the
                  puried water system of workshops was used; steam condensate was diverted to the production auxiliary
                  system of the hot water tank and the crystallizing tank for use; the lights in the public areas and corridors
                  of workshops were changed to voice-controlled or light-controlled ones; LED lights were used in
                  workshops; and high energy-consumption equipment and facilities in workshops were gradually replaced
                  with low energy- consumption or automatic interlocking ones.
                  The company further strengthened daily energy conservation management according to existing energy
                  conservation plan, eectively enhanced energy conservation awareness of employees through inspection
Shanghai Livzon   and publicity, and encouraged employees to develop the good habit of water and power conservation.
                  Meanwhile, the company improved more than 10% of peptide yield by optimizing peptide process so as
                  to reduce power consumption of unit product.




                                                                                                                           107
 II Corporate Social responsibility
      √ Applicable □ N/A


      Joincare is striving to be an explorer in the healthcare industry and insisting on creating a healthy life driven by technology.
      The Group pays great attention to its sustainable development, and actively focuses on the internal regulatory environment and
      external policy guidance. Considering China's 14th Five-Year Plan and the local government's development plan, the Group
      has formulated a CSR strategy and goals adapting to its current business situation.

      Focusing on“health”, the Group's CSR strategy aims to provide the whole society with high-quality, safe, accessible and
      affordable medical products and services through the development of its principal businesses, while improving the overall
      strength of the health industry. Meanwhile, the strategy is committed to empowering employees and communities, emphasizing
      environmental protection and promoting the overall health development in society.

      The development of enterprises relies on society. Over the years, the Company has conscientiously fulfilled its social
      responsibility, paid taxes according to law, supported social public welfare projects, and actively assumed its social
      responsibility for building a harmonious society. At the same time, the Group was actively creating social value. It generated
      tax revenues for the government of RMB 1,653 million, paid RMB 1,951 million in salary to employees, distributed dividends
      and paid interest worth RMB1,271 million to banks and other creditors, donated funds and goods totaling RMB 29.10 million
      to the society, and achieved a social contribution per share of ap proximately RMB 2.57 for the society in 2021 For our
      performance of social responsibility, see the 2021 Corporate Social Responsibility Report of Joincare Pharmaceutical Industry
      Group Co., Ltd. disclosed by the Company on the website of Shanghai Stock Exchange (www.sse.com.cn) on 31 March 2022
      for details.


III Consolidation and expansion of achievements in poverty alleviation and rural revitalization
      √ Applicable □ N/A


 1. Industrial revitalization

      The Company fully implements the spirit of the important instructions put forward by the CPC Central Committee and the
      General Secretary. In accordance with the relevant requirements, we establish the plan of“Astragalus Root ( 黄 芪 ) Industry”
      and adopt the model of“Company + Base”and“Company + Professional Cooperative”, encouraging locals to cultivate
      and process astragalus root and develop the astragalus root industry with reference to the local conditions to make it a pillar
      industry for poverty relief in the long-term. The Company will explore the development of the featured astragalus root industry
      to achieve poverty elimination and promote the construction of the“Chinese Medicine Ecological Base”.

      During the Reporting Period, Datong Livzon Qiyuan Medicine Co., Ltd. ( 大 同 丽 珠 芪 源 药 材 有 限 公 司 ) (“Datong
      Livzon”), a subsidiary of the Company's controlling subsidiary Livzon Group, has employed 95 local workers for the self-
      built base and jointly constructed base.




108
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2. Access to public welfare for chronic diseases prevention and treatment

   In supporting consolidation and expansion of achievements in poverty alleviation and rural revitalization and In order to
   respond positively to the call of national policy, Joincare have launched“Access to Public Welfare for Chronic Diseases
   Prevention and Treatment ( 普 惠 慢 病 防 治 公 益 项 目 )”program by combining our own industrial advantages. The program
   targets at hypertension, hyperlipidemia, cardiovascular and cerebrovascular diseases, and drugs for treatment of chronic
   diseases have been donated to remote areas, including Pravastatin Capsules ( 普 伐 他 汀 钠 胶 囊 ), Amlodipine Besylate
   Capsules ( 苯 磺 酸 氨 氯 地 平 胶 囊 ), Valsartan Capsules ( 缬 沙 坦 胶 囊 ), and Isosorbide Bononitrate Tablets ( 单 硝 酸 异 山 梨
   酯 片 ), which could be worth millions of RMB. These drugs can really help families in remote areas, make it convenient for
   patients in the regions to take drugs nearby, help the families with patients to alleviate medical pressures, and provide timely
   assistance. Based on actual conditions, the project regularly makes continuous drug donations to remote areas and helps the
   families with patients in such regions.

  Since late 2018 onwards, with the support of local government agencies and relevant authorities at all levels, we carried out the
  “Inclusive Chronic Disease Prevention and Control Public Welfare Project”successively in areas including Chaotian District
    of Guangyuan City, Songpan County, Jiange County and Pingwu County of the Autonomous Prefecture of Aba Zangs and
  Qiangs in Sichuan Province, Hunyuan County, Guangling County and Lingqiu County of Datong City in Shanxi Province,
  Dongxiang County and Tianzhu County in Gansu Province, Xianghai national nature reserve in Jilin Province, Chayu County
  in Tibet Autonomous Region, Macun District of Jiaozuo City in Henan Province, Huangshan District of Huangshan City in
  Anhui Province, Suining County of Hunan Province, and Fenyi County of Jiangxi Province, bringing benets to many patients.
  Joincare won the awards of“2021 China Brand Influence - Model for Undertaking Social Responsibility”and“2021 Model
    for Rural Revitalization”for its excellent projects supporting urban revitalization.

    As at 31 December 2021, the project covered 8 provinces and one autonomous region, among which 14 were remote areas
    in need of help and one was natural reserve at state level, and there were more than 5,000 registered people. In 2022, it is
    expected to donate drugs to areas including Hubei, Gansu and Sichuan.


3. Charitable projects for students

   One of the education policies of the CPC and the state is to subsidize students in poverty to complete their studies, which is
   vital to talent training and social progress and is the common responsibility of the whole society. With the great support and
   help of the National Medical Products Administration, the Company has donated RMB900,000 in total to poor college students
   in Linquan County in three years since 2019 and shouldered its responsibility to the society. The student grant program is set
   by the National Medical Products Administration for poor college students in Linquan County, Fuyang City, Anhui Province
   majoring in pharmaceutical in colleges and universities. The grant standard is RMB5,000 per undergraduate and RMB3,000
   per junior college student for more than a hundred students. The program aims to improve the learning and living conditions
   of those students and help them to better complete their studies so as to train more talents for the national pharmaceutical
   undertaking.

   The proposed grant of RMB300,000 for 2021 has been awarded. Up to now, the grant of RMB900,000 planned to be donated
   has been awarded and the total number of project participants is more than 180.


4. Assist Henan's Flood Relief

    In 2021, a record-breaking extreme heavy and persistent rainfall occurred in Henan province, causing serious waterlogging and
    other disasters in many parts of Henan, imposing great pressure on flood control. Providing Strong Support to Disaster Areas
    Joincare Pharmaceutical Group and Livzon Pharmaceutical Group supported Henan by jointly donating RMB 10 million in
    cash and RMB 10 million worth of medicines through China Red Cross Foundation, joining the Government and other sectors
    of the society in an effort to ensure the safety of Henan locals, to procure emergency relief materials and to assist disaster
    recovery.




                                                                                                                                    109
      Chapter 6
      Major Events


 I Fulfillment of undertakings

 (I) Undertakings fulfilled during the Reporting Period or not yet fulfilled as of the Reporting Period by the parties to the
     commitment such as de facto controllers, shareholders, related parties, acquirers of the Company and the Company
      √ Applicable □ N/A

                                                                                                                                                                                            Specic      Next plan
                                                                                                                                                               Whether     Whether
                                                                                                                                                                                            reasons     should be
                                                                                                                                              Time and          there is commitment
      Commitment Commitment                                                                                                                                                               for failure stated in case
                            Subject                                                   Commitment content                                      time limit of      a time   is strictly
      background type                                                                                                                                                                      in timely    of failure
                                                                                                                                              commitment       limit for fullled in
                                                                                                                                                                                          fulllment     in timely
                                                                                                                                                              fulllment      time
                                                                                                                                                                                        shall be given fulllment
                                                      Shenzhen Baiyeyuan Investment Co., Ltd., a controlling shareholder of the Company,
                                                      undertook that it would not be directly or indirectly engaged in or cause subsidiaries
                                                      and branches under its control to be engaged in any business or activity constituting
                       Settlement                                                                                                              30 April
                                                      horizontal competition with the Company after the founding of the Company, including
                       of horizontal   Baiyeyuan                                                                                               2001,             No          Yes              -              -
                                                      but not limited to the research, production and sales of any products that were the same
                       competition                                                                                                             long-term
                                                      as or similar to products under research, production and sales of the Company, and was
                                                      willing to undertake compensation responsibility for economic losses to the Company
                                                      arising from violation of the said commitment.
                                                    Whereas the domestically listed foreign shares of Livzon Group, a controlling
                                                    subsidiary of the Company, would be listed on the Main Board of the Stock Exchange
                                                    of Hong Kong Limited, in order to fully ensure smooth completion of the said event
                                                    and in compliance with relevant requirements of the Stock Exchange of Hong Kong
                                                    Limited, the controlling shareholders and de facto controller of the Company, and
                                                    the Company entered into relevant undertakings with Livzon Group as follows: 1.
                                                    The controlling shareholders, de facto controller and persons acting-in-concert of the
                                                    Company, the Company and its controlling subsidiaries except for Livzon Group did
                                                    not or would not be, directly or indirectly, engaged in any business that constituted
                                                    competitive relation or potential competitive relation with drug research, development,
                                                    production and sale businesses (“Restricted Businesses”) of Livzon Group from
                                                    time to time. For the avoidance of doubt, the scope of Restricted Businesses did not
      Commitment
                                                    cover products that were researched, developed, manufactured and sold on the date of
      related to
                                                    relevant letter of undertaking by the controlling shareholders and de facto controller of
      initial public
                                       Baiyeyuan, the Company, the Company and its controlling subsidiaries except for Livzon Group;
      oering
                                       de facto     2. If any new business opportunity was found to constitute competitive relation with
                       Settlement      controllers  Restricted Businesses, the controlling shareholders, de facto controllers and persons 10 January
                       of horizontal   and persons acting-in-concert of the Company, the Company and its controlling subsidiaries except 2014,                   No          Yes              -              -
                       competition     acting-in-   for Livzon Group would inform Livzon Group in written form immediately and rstly long-term
                                       concert, and provide Livzon Group with the business opportunity in accordance with reasonable
                                       the Company and fair terms and conditions. If Livzon Group gave up the business opportunity, the
                                                    controlling shareholders and de facto controllers of the Company, the Company and its
                                                    controlling subsidiaries except for Livzon Group may accept the business opportunity
                                                    in accordance with the terms and conditions that were not superior to those offered
                                                    to Livzon Group; 3. If assets and businesses that directly or indirectly constituted
                                                    competitive relation and potential competitive relation with Restricted Businesses
                                                    were intended to be transferred, sold, leased, licensed to use or otherwise transferred
                                                    or allowed to use (these Sales and Transfers), the controlling shareholders and de
                                                    facto controllers of the Company, the Company and its controlling subsidiaries except
                                                    for Livzon Group would provide the right of first refusal for Livzon Group under
                                                    the same condition. If Livzon Group gave up the right of rst refusal, the controlling
                                                    shareholders, de facto controllers and persons acting-in-concert of the Company, the
                                                    Company and its controlling subsidiaries except for Livzon Group would carry out
                                                    these Sales and Transfers to a third party in accordance with main terms that were not
                                                    superior to those oered to Livzon Group;




110
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                                                                                                                                                                              Specic      Next plan
                                                                                                                                                Whether     Whether
                                                                                                                                                                              reasons     should be
                                                                                                                                 Time and        there is commitment
Commitment Commitment                                                                                                                                                       for failure stated in case
                      Subject                                            Commitment content                                      time limit of    a time    is strictly
background type                                                                                                                                                              in timely    of failure
                                                                                                                                 commitment limit for      fullled in
                                                                                                                                                                            fulllment     in timely
                                                                                                                                               fulllment       time
                                                                                                                                                                          shall be given fulllment
                                       4. The controlling shareholders, de facto controllers and persons acting-in-concert of
                                       the Company, the Company and its controlling subsidiaries except for Livzon Group
                                       would not be engaged in or involved in any business that might damage the interests of
                                       Livzon Group and other shareholders through the relation with shareholders of Livzon
                                       Group or the identity of shareholders of Livzon Group; 5. The controlling shareholders,
                                       de facto controllers and persons acting-in-concert of the Company, the Company and
                                       its controlling subsidiaries except for Livzon Group would not or cause its contact
                                       persons (except for Livzon Group) to directly or indirectly: (1) induce or attempt to
                                       induce any director, senior management or consultant of any member of Livzon Group
                                       to terminate his/her employment with or to be an employee or consultant of Livzon
                                       Group at any time (whichever is applicable), no matter if relevant acts of the person
                                       were against the Employment Contract or Consultancy Agreement (if applicable); (2)
                                       Within three years after any person terminated to be the director, senior management or
                                       consultant of any member of Livzon Group, employ the person who had or might have
                                       any confidentiality information or business secret in relation to Restricted Businesses
                                       (except for the director, senior management or consultant of the Company and/or its
                                       controlling subsidiaries except for Livzon Group on the date of issuance of relevant
                                       letter of undertaking); (3) Recruit or lobby any person carrying out business in any
                                       member of Livzon Group, accept orders, or carry out business separately, through any
                                       other person or as any person, firm, or manager, advisor, consultant, employee, agent
                                       or shareholder of any company (competitor of any member of Livzon Group), or lobby
                                       or persuade the person making transaction with Livzon Group or negotiating with
                           Baiyeyuan,
                                       Livzon Group on Restricted Businesses to terminate its transaction with Livzon Group
                           de facto
                                       or reduce its normal business volume with Livzon Group, or ask for more favorable
                           controllers transaction terms to any member of Livzon Group. 6. The controlling shareholders,
           Settlement                                                                                                             10 January
                           and persons de facto controllers and persons acting-in-concert of the Company, the Company and
           of horizontal                                                                                                          2014,           No           Yes              -              -
                           acting-in- its controlling subsidiaries except for Livzon Group further undertook that: (1) They
           competition
                           concert,    would allow and cause relevant contact persons (except for Livzon Group) to allow long-term
                                       independent directors of Livzon Group to review if the Company and its controlling
                           and the
                                       subsidiaries except for Livzon Group obeyed the Letter of Undertaking at least once a
                           Company
                                       year; (2) They would provide all the data required for annual review and implementation
                                       of the Letter of Undertaking for independent directors of Livzon Group; (3) They would
                                       allow Livzon Group to disclose the decision on whether the controlling shareholders
                                       and de facto controllers of the Company, the Company and its controlling subsidiaries
                                       except for Livzon Group obeyed and implemented the Letter of Undertaking reviewed
                                       by independent directors of Livzon Group through the annual report or announcement;
                                       (4) The controlling shareholders, de facto controllers and persons acting-in-concert of
                                       the Company, the Company (and its controlling subsidiaries except for Livzon Group)
                                       would provide Livzon Group with the Letter of Conrmation in relation to compliance
                                       with clauses of the Letter of Undertaking every year so as to be included in the annual
                                       report of Livzon Group. 7. The controlling shareholders, de facto controllers and persons
                                       acting-in-concert of the Company, and the Company undertake that they would bear
                                       corresponding legal responsibility and consequence arising from violation of any clause
                                       in relevant letter of undertaking from the date of issuance thereof by the Company (or
                                       the Company's controlling subsidiaries except for Livzon Group or its contact persons).
                                       8. The said undertakings would terminate in case of the following circumstances
                                       (whichever is earlier): (1) The controlling shareholders, de facto controllers and persons
                                       acting-in-concert of the Company, the Company and any of its holding subsidiary
                                       were not the controlling shareholders of Livzon Group any more; (2) Livzon Group
                                       terminated the listing of its shares on the Hong Kong Stock Exchange and other overseas
                                       stock exchanges (except that shares of Livzon Group stopped to be traded temporarily
                                       for any reason).




                                                                                                                                                                                                   111
                                                                                                                                                                                     Specic      Next plan
                                                                                                                                                       Whether     Whether
                                                                                                                                                                                     reasons     should be
                                                                                                                                  Time and              there is commitment
      Commitment Commitment                                                                                                                                                        for failure stated in case
                            Subject                                      Commitment content                                       time limit of          a time    is strictly
      background type                                                                                                                                                               in timely    of failure
                                                                                                                                  commitment           limit for  fullled in
                                                                                                                                                                                   fulllment     in timely
                                                                                                                                                      fulllment       time
                                                                                                                                                                                 shall be given fulllment
                                                                                                                         From 8 March
                                                                                                                         2016 to the date
                                                                                                                         of completion
      Commitment             The
                                                                                                                         of remedial
      related to             Company      Do not interfere in the operation and management activities of Livzon Group or
                 Others                                                                                                  measures in                     Yes          Yes              -              -
      seasoned               and de facto encroach on the interests of Livzon Group
                                                                                                                         connection with
      oerings                controllers
                                                                                                                         the non-public
                                                                                                                         oering of
                                                                                                                         Livzon Group
                                          Pursuant to the Guiding Opinions on Matters Relating to the Dilution of Current
                                          Returns As a Result of Initial Public Offering, Refinancing and Major Asset
                                          Restructuring (Announcement of CSRC [2015] No. 31), the Company shall
                                          undertake to adopt specific remedial measures relating to dilution of current
                                          returns as a result of the Company's initial public offering, refinancing of the
                                          listed company, or major asset restructuring and shall fulfill such undertaking.
                                          Pursuant to relevant provisions of CSRC, Zhu Baoguo, the de facto controller
                                          of Shenzhen Baiyeyuan Investment Co., Ltd., a controlling shareholder of the
                                          Company, made the following undertakings in order to practically take remedial
                                          measures in relation to returns: 1. Do not intervene in the operation and management
                                                                                                                                  From 11 May
                                          activities or encroach on the interests of the Company; 2. If CSRC issued other
                                                                                                                                  2017 to the date
                                          new regulatory provisions on the remedial measures in relation to returns and
                             Baiyeyuan                                                                                            of completion
                                          the relevant undertakings and the aforesaid undertakings did not conform to such
                             and the                                                                                              of remedial
                   Others                 provisions from the date of issuance of the undertaking to the completion of IPO                               Yes          Yes             -               -
                             de facto                                                                                             measures in
                                          share allotment, the Company/the de facto controller would undertake to issue a
                             controller                                                                                           connection
                                          supplemental undertaking in accordance with the latest provisions of CSRC; 3. The
                                                                                                                                  withrights issue
                                          Company/the de facto controller undertook to practically take the remedial measures
      Commitment                                                                                                                  of Joincare
                                          in relation to returns formulated by the Company and fulfill the undertaking
      related to
                                          concerning the remedial measures. In case of violation of the undertaking, causing
      seasoned
                                          losses to the Company or investors, the Company/the de facto controller was willing
      oerings
                                          to assume compensation responsibilities to the Company or investors in accordance
                                          with law. In case of violation of the said undertakings or rejection to fulfill the
                                          said undertakings, as one of the liability subjects relating to the remedial measures
                                          concerning returns, it was agreed that relevant punishment shall be imposed on or
                                          relevant management measures shall be taken against the Company/the de facto
                                          controller by CSRC, the Shanghai Stock Exchange and other securities regulators in
                                          accordance with relevant provisions and rules set or issued by them.
                                          After the proceeds for issuance of allotment were in place, the Company would use
                                                                                                                                  From the date
                                          them according to contents disclosed in the announcement, and carry out deposit in
                                                                                                                                  of proceeds
                                          special account, approval by specially-assigned person, and special use of special
                                                                                                                                  for issuance
                                          funds in accordance with management measures for proceeds of the Company. The
                                                                                                                                  of the Rights
                             The          Board of the Company would regularly check the progress of projects invested
                   Others                                                                                                         issue in place         Yes          Yes              -              -
                             Company      with proceeds, issue a special report on deposit and use of proceeds, engage an
                                                                                                                                  to the date of
                                          accounting rm during the annual audit to issue an verication report on deposit and
                                                                                                                                  completion of
                                          use of proceeds, would be supervised by regulators and sponsors at any time, and
                                                                                                                                  use of proceeds
                                          would not make major investment, asset purchase or similar financial investment
                                                                                                                                  for rights issue.
                                          though proceeds in disguise.
                                          1. While transferring tradable shares subject to selling restrictions held by the
      Other
                                          Company in Livzon Group, the Company shall strict obey relevant provisions of
      commitments
                                          Guidelines of Listed Companies on Transfer of Stock Shares Subject to Selling
      made to the
                                          Restrictions ([2008] No. 15); 2. If the Company had shares subject to selling
      medium                 The                                                                                            17 December
                   Others                 restrictions held by it in Livzon Group that were planned to be sold through the                               No           Yes              -
      and small              Company                                                                                        2008, long-term
                                          bid trading system of Shenzhen Stock Exchange and reduced more than 5% shares
      shareholders
                                          within six months from the first share reduction, the Company would pass the
      of the
                                          Announcement on Sales disclosed by Livzon Group within two trading days before
      Company
                                          the rst share reduction.




112
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                                                                                                                         2021


 (II) If the Company has made profit forecast on its assets or projects and the Year is still within the profit forecast period, the
      Company shall give an explanation on why its assets or projects achieved its profit forecast
     □ Realized □ Unrealized √ N/A


(III) Fulfillment of performance covenant and its influence on goodwill impairment test
     □ Applicable √ N/A


 II Information on Non-operating use of funds by controlling shareholders and other related
    parties during the Reporting Period
     □ Applicable √ N/A


III Information on Illegal guarantees
     □ Applicable √ N/A


 IV TheBoard'sstatementonthe“non-standardopinionauditor'sreport”issuedbythe
    appointed accounting firm
     □ Applicable √ N/A


 V Analysis and explanation from the Company on the reasons and impact of the change of
   accounting policies, accounting estimates or correction on significant accounting errors

 (I) Analysis and explanation from the Company on the reasons and impact of the change of accounting policies or
     accounting estimates
     □ Applicable √ N/A


 (II) Analysis and explanation from the Company on the reasons and impact of the correction on significant accounting
      errors
     □ Applicable √ N/A


(III) Communication with former accounting firm
     □ Applicable √ N/A


(IV) Others
     □ Applicable √ N/A




                                                                                                                               113
VI Appointment and termination of appointment of accounting firm
                                                                                                    Unit: 10,000 Yuan Currency: RMB
                                                                                      Current accounting rm
      Name of domestic accounting rm                                                  Grant Thornton (Special General Partnership)
      Remuneration for domestic accounting rm                                                                                    128
      Continuous years of auditing services provided by domestic accounting rm                                                     3


                                                                                     Name                                  Fee
      Accounting rm for internal control audit                   Grant Thornton (Special General Partnership)               32


      Statement on appointment and termination of appointment of accounting rm
      □ Applicable √ N/A

      Statement on re-engagement of accounting rm during the audit period
      □ Applicable √ N/A


VII Risk of delisting

 (1) Reasons for delisting risk warning
     □ Applicable √ N/A

 (2) Countermeasures to be taken by the Company
     □ Applicable √ N/A

 (3) Risk of delisting and the reasons
     □ Applicable √ N/A


VIII Matters related to bankruptcy and reorganization

      □ Applicable √ N/A


IX Material litigation and arbitration
      □ The Company was involved in material litigation or arbitration in current year
      √ The Company was not involved in material litigation or arbitration in current year


 X Violations committed by the listed company and its directors, supervisors, senior
   management, controlling shareholders and de facto controllers, punishments imposed
   and rectifications
      □ Applicable √ N/A


XI Credit standing of the Company and its controlling shareholders and de facto controllers
   during the Reporting Period
      □ Applicable √ N/A




114
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XII Material related-party transactions

(I) Related-party transactions in connection with day-to-day operation
1. Matters already disclosed in interim announcements about which no new information is available
   √ Applicable □ N/A


                                      Overview                                                             Query index
    Pursuant to the“Resolution on Connected Transactions in the Ordinary             See the Announcement on Resolutions Considered and
    Course of Business of the Majority-owned Subsidiaries of Jiaozuo Joincare         Approved at the 44th Meeting of the 7th Session of
    and Jinguan Electric Power”considered and approved at the 44th Meeting           the Board of Joincare Pharmaceutical Group Industry
    of the 7th Session of the Board on 29 March 2021, Jiaozuo Joincare intended       Co., Ltd. (Lin 2021-033) and the Announcement of
    to purchase no more than RMB 200 million (inclusive) of steam and power           Joincare Pharmaceutical Group Industry Co., Ltd. on
    from Jinguan Electric Power in 2021 so as to satisfy the demands of Jiaozuo       the Connected Transactions in the Ordinary Course of
    Joincare for steam and power in the process of production and operation. The      Business of the Majority-owned Subsidiaries of Jiaozuo
    independent directors of the Company gave prior approval opinions on the          Joincare and Jinguan Electric Power (Lin 2021-038)
    Resolution and gave opinions on the approval at the Board meeting.                disclosed by the Company on 31 March 2021 for details.
    The“Resolution on the Adjustment of Forecast of Connected Transactions in
    the Ordinary Course of Business of the Majority-owned Subsidiary Jiaozuo
    Joincare and Jinguan Electric Power”was considered and approved at the
    4th Meeting of the 8th Session of the Board on 15 November 2021: given            See the Announcement on Resolutions Considered
    that the prices of coal and other raw materials in the market have been rising    and Approved at the 4th Meeting of the 8th Session of
    considerably since Q3 2021, and the actual power consumption of Jiaozuo           the Board of Joincare Pharmaceutical Group Industry
    Joincare was higher than forecast at the beginning of the year, to satisfy the    Co., Ltd. (Lin 2021-135) and the Announcement of
    demands of Jiaozuo Joincare for steam and power in the process of production      Joincare Pharmaceutical Group Industry Co., Ltd. on the
    and operation, the cap of the connected transaction, that is, purchase of steam   Adjustment of Projection of Connected Transactions in
    and power from Jinguan Electric Power, was changed from RMB 200 million           the Ordinary Course of Business of the Majority-owned
    (inclusive) to RMB 220 million (inclusive) in 2021. The independent directors     Subsidiaries of Jiaozuo Joincare and Jinguan Electric
    of the Company gave prior approval opinions on the Resolution and gave            Power (Lin 2021-137) disclosed by the Company on 16
    opinions on the approval at the Board meeting.                                    November 2021 for details.
    Both parties referred to the market price to fix a price of the said connected
    transactions. During the Reporting Period, the actual amount of the said
    connected transactions was RMB 212.586 million.


2. Matters already disclosed in interim announcements about which new information is available
   □ Applicable √ N/A

3. Matters not disclosed in interim announcements
   □ Applicable √ N/A


(II) Related-party transactions involving acquisition or sale of assets or equity
1. Matters already disclosed in interim announcements about which no new information is available
   □ Applicable √ N/A

2. Matters already disclosed in interim announcements about which new information is available
   □ Applicable √ N/A

3. Matters not disclosed in interim announcements
   □ Applicable √ N/A

4. Fulllment of performance covenants (if any) during the Reporting Period
   □ Applicable √ N/A



                                                                                                                                         115
(III) Material related-party transactions involving joint external investment
 1. Matters already disclosed in interim announcements about which no new information is available
    □ Applicable √ N/A

 2. Matters already disclosed in interim announcements about which new information is available
    □ Applicable √ N/A

 3. Matters not disclosed in interim announcements
    □ Applicable √ N/A


(IV) Claims and debts with related parties
 1. Matters already disclosed in interim announcements about which no new information is available
    □ Applicable √ N/A

 2. Matters already disclosed in interim announcements about which new information is available
    □ Applicable √ N/A

 3. Matters not disclosed in interim announcements
    √ Applicable □ N/A
                                                                                                                                          Unit: Yuan Currency: RMB
                                                                                   Oer funds to related parties                  Receive funds from related parties
                                                                                               Amount                                             Amount
      Related party                                       Relationship        Opening                           Closing          Opening                        Closing
                                                                                        incurred in the                                    incurred in the
                                                                               balance                          balance           balance                        balance
                                                                                         current period                                     current period
      Guangdong Blue Treasure Pharmaceutical Co.,
                                                          Others          5,092,960.00   20,560,996.55 25,653,956.55                  0.00      379,960.00 379,960.00
      Ltd.* ( 广东蓝宝制药有限公司 )
      L&L Biopharma, Co. Ltd.
                                                          Others          1,740,994.29    -1,740,994.29             0.00
      ( 上海健信生物医药科技有限公司 )
      Shenzhen Jiekang Health Care Co., Ltd.*
                                                          Others         18,577,246.63             0.00 18,577,246.63
      ( 深圳市捷康保健有限公司 )
      Shenzhen Health Deer Technology Co., Ltd.(深
                                                          Others                  0.00         4,680.00         4,680.00
      圳市健康阿鹿信息科技有限公司)
      Shenzhen City Youbao Technology Co., Ltd. *
                                                          Others                  0.00       154,500.00       154,500.00
      ( 深圳市有宝科技有限公司 )
      Sichuan Healthy Deer Hospital Management Co.,
      Ltd. and its subsidiaries                           Others           153,900.00        183,495.02       337,395.02              0.00         8,936.17      8,936.17
      ( 四川健康阿鹿医院管理有限公司及其子公司 )
      Zhongshan Renhe Health Product Co., Ltd.
                                                          Others           469,895.78              0.00       469,895.78
      ( 中山市仁和保健品有限公司 )
      Zhuhai Sanmed Biotech Inc.*
                                                          Others         15,211,200.00 -15,000,000.00         211,200.00
      ( 珠海圣美生物诊断技术有限公司 )
      Zhuhai Sanmed Gene Diagnostics Ltd.*
                                                          Others            49,093.14        180,195.69       229,288.83
      珠海市圣美基因检测科技有限公司
      Zhuhai Zhong Hui Yuan Investment Partnership
      (Limited Partnership) *                             Others         10,967,767.26 -10,967,767.26               0.00     1,466,606.04     -1,466,606.04          0.00
      ( 珠海中汇源投资合伙企业(有限合伙))
      Jiaozuo Jinguan Jiahua Electric Power Co., Ltd. *   Associated
                                                                                     0     8,240,517.56     8,240,517.56    31,681,080.57 -31,681,080.57                   0
      ( 焦作金冠嘉华电力有限公司 )                        company
      Total                                                              52,263,057.10 1,615,623.27 53,878,680.37 33,147,686.61 -32,758,790.44 388,896.17
                                                                         During the Reporting Period, the Company had normal operating fund transactions with
      Cause for claims and debts with related parties
                                                                         connected parties.
                                                                         The said credits and debts with connected persons are operating fund transactions; there was no
      Impact of claims and debts with related parties on the Company
                                                                         non-operating use of funds of the Company by shareholders and connected part




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(V) Financial business among the Company, related financial companies, financial companies controlled by the Company,
    and related parties
    □ Applicable √ N/A


(VI) Others
    □ Applicable √ N/A


XIII Material contracts and their performance

 (I) Trusteeship, contracting and lease
 1. Trusteeship
    □ Applicable √ N/A

 2. Contracting
    □ Applicable √ N/A

 3. Lease
    □ Applicable √ N/A


(II) Guarantees
    √ Applicable □ N/A
                                                                                                                                                     Unit: 10,000 Yuan Currency: RMB
                                                      External guarantees provided by the Company (excluding those provided for its subsidiaries)
                Relationship                                      Date of
                                                                                                                                                             Whether
                between the                                       guarantee                                                                                              Guaranteed
                                                    Guaranteed                  Eective       Expiration Guarantee            Fullled Overdue Overdue        there's a                   Relationship
     Guarantor guarantor         Guaranteed party                 (signing                                                                                               for a related
                                                       amount                   date          date          type              or not     or not     amount   counter-
                and the listed                                    date of                                                                                                party or not
                                                                                                                                                             guarantee
                company                                           agreement)
                Headquarter of Jinguan Electric                                                             Joint liability
     Joincare                                         4,800.00 2021/2/23        2021/2/23     2022/2/23                        No         No          0        Yes           Yes          Associate
                the Company      Power                                                                      guarantee
                Headquarter of Jinguan Electric                                                             Joint liability
     Joincare                                        10,000.00 2021/3/3         2021/3/3      2022/2/25                        No         No          0        Yes           Yes          Associate
                the Company      Power                                                                      guarantee
                Headquarter of Jinguan Electric                                                             Joint liability
     Joincare                                         4,000.00 2021/7/8         2021/7/8      2022/7/8                         No         No          0        Yes           Yes          Associate
                the Company      Power                                                                      guarantee
                Headquarter of Jinguan Electric                                                             Joint liability
     Joincare                                         5,000.00 2021/7/14        2021/7/14     2022/7/14                        No         No          0        Yes           Yes          Associate
                the Company      Power                                                                      guarantee
                Headquarter of Jinguan Electric                                                             Joint liability
     Joincare                                         3,000.00 2021/7/16        2021/7/16     2022/6/16                        No         No          0        Yes           Yes          Associate
                the Company      Power                                                                      guarantee
                Headquarter of Jinguan Electric                                                             Joint liability
     Joincare                                         3,000.00 2021/8/12        2021/8/12     2022/8/12                        No         No          0        Yes           Yes          Associate
                the Company      Power                                                                      guarantee
                Headquarter of Jinguan Electric                                                             Joint liability
     Joincare                                         3,200.00 2021/9/23        2021/9/23     2022/9/22                        No         No          0        Yes           Yes          Associate
                the Company      Power                                                                      guarantee
                Headquarter of Jinguan Electric                                                             Joint liability
     Joincare                                         3,200.00 2021/10/11       2021/10/11 2022/10/11                          No         No          0        Yes           Yes          Associate
                the Company      Power                                                                      guarantee
                Headquarter of Jinguan Electric                                                             Joint liability
     Joincare                                         3,800.00 2021/10/13 2021/10/13 2022/10/12                                No         No          0        Yes           Yes          Associate
                the Company      Power                                                                      guarantee
                Holding                                                                                     Joint liability
     Livzon                      Sanmed Biotech       2,900.00 2021/1/1         2021/1/1      2021/5/6                         Yes        No          0        Yes           Yes          Associate
                subsidiary                                                                                  guarantee




                                                                                                                                                                                                117
      Total guaranteed amount occurred during the Reporting Period (excluding guarantees to subsidiaries)                                           42,900.00
      Total guaranteed amount as of the end of the Reporting Period (A) (excluding guarantees to subsidiaries)                                      40,000.00
                                                                       Guarantee provided by the Company and its subsidiaries to subsidiaries
      Total amount of guarantees to subsidiaries during the Reporting Period                                                                       276,627.03
      Total amount of guarantees to subsidiaries as of the end of the Reporting Period (B)                                                         164,656.89
                                                                   Total guaranteed amount of the Company (including guarantees to subsidiaries)
      Total guaranteed amount (A+B)                                                                                                                204,656.89
      Percentage of total guaranteed amount in the Company's net assets (%)                                                                             10.14
      In which:
      Amount of guarantees provided to shareholders, de facto controllers and their related parties (C)                                                    0
      Amount of debt guarantee directly or indirectly provided to a guaranteed party with an asset-liability ratio exceeding 70% (D)               121,966.71
      Portion of total guaranteed amount exceeding 50% of net assets (E)                                                                                   0
      Total guaranteed amount of the above three items (C+D+E)                                                                                     121,966.71
      Statement on the contingent joint liability that might be assumed in connection with outstanding guarantee                                         N/A
      Statement on guarantees                                                                                                                               -


(III) Entrusted cash asset management
 1. Entrusted wealth management

 (1) Overall situation of entrusted wealth management
     □ Applicable √ N/A

      Other information
      □ Applicable √ N/A

 (2) Single entrusted wealth management
     □ Applicable √ N/A

      Other information
      □ Applicable √ N/A

 (3) Provision for impairment of entrusted wealth management products
     □ Applicable √ N/A

 2. Entrusted loans

 (1) Overall situation of entrusted loans
     □ Applicable √ N/A

      Other information
      □ Applicable √ N/A

 (2) Single entrusted loans
     □ Applicable √ N/A

      Other information
      □ Applicable √ N/A

 (3) Provision for impairment of entrusted loans
     □ Applicable √ N/A

 3. Other information
    □ Applicable √ N/A


(IV) Other material contracts
      □ Applicable √ N/A



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XIV Other significant matters having significant influence on the value judgment and decisions
    of investors
    √ Applicable □ N/A


 1. Use of proceeds

    Pursuant to the Reply to the Approval of Share Allotment of Joincare Pharmaceutical Group Industry Co., Ltd. issued by
    CSRC (Zheng Jian Xu Ke [2018] No. 1284), the Company allotted 365,105,066 shares to original shareholders. Total amount
    of actual proceeds for the allotment was RMB1,715,993,810.20; the deducted distribution expenses were RMB46,253,565.29;
    the net amount of proceeds was RMB1,669,740,244.91. As at 16 October 2018, the said proceeds were in place and validated
    by the Capital Verification Report of Joincare Pharmaceutical Group Industry Co., Ltd. issued by Ruihua Certified Public
    Accountants (Rui Hua Yan Zi [2018] No. 40060006).

    As at 31 December 2021, the use of proceeds was as follows:
                                                                                                                 Unit: 10,000 Yuan
                                      Total amount of        Total amount of       Use of proceeds as    Balance of proceeds as
     Project name
                                           investment    proceeds investment    at 31 December 2021       at 31 December 2021
     Zhuhai Health Industry Base
                                           98,066.84               76,974.02                 3,386.29                 73,587.73
     Construction Project
     Haibin Pharma Pingshan
     Pharmaceutical                       125,471.35               90,000.00                66,745.58                 23,254.42
     Industrialization Base Project
     Total                                223,538.19              166,974.02                70,131.87                 96,842.15


    Pursuant to the Resolution on the Temporary Replenishment of Working Capital with Idle Proceeds considered and approved
    at the 37th Meeting of the 7th Session of the Board of the Company on 30 December 2020, it was agreed that the Company
    temporarily replenished the working capital with no more than RMB 900 million of idle proceeds from 1 January 2021 to 31
    December 2021 so as to improve the use eciency of proceeds and reduce nancial expenses of the Company. On 9 February
    2021, the Company repaid RMB 40 million to the special account for proceeds ahead of schedule; and returned the temporary
    replenishment of working capital was RMB 860 million to the special account.

    Pursuant to the Resolution on Cash Management with Idle Proceeds considered and approved, it was agreed that the Company
    carried out cash management with no more than RMB 250 million of idle proceeds and purchased principal-guaranteed bank
    cash management products with high security and good liquidity or deposit products with high revenues, without prejudice
    to the implementation of projects invested with proceeds and the use of proceeds. Duration of the said cash management was
    from 1 January 2021 to 31 December 2021; the funds may be used on revolving basis within the limit. As of 31 December,
    2021, all cash management products purchased by the Company have been withdrawn due to maturity.

    Pursuant to the Resolution on Extension of Certain Projects Invested with Proceeds considered and approved at the 44th
    Meeting of the 7th Session of the Board of the Company on 29 March 2021, it was approved that the Company extended the
    construction start time of Zhuhai Health Industry Base Construction Project to the second half of 2021; the specic start time
    was up to the date of completion for construction of municipal supporting works on project construction site. The resolution
    was considered and approved at the 2020 annual general meeting convened by the Company on 21 May 2021. For details,
    see the Announcement of Joincare Pharmaceutical Group Industry Co., Ltd. on Extension of Certain Projects Invested with
    Proceeds disclosed by the Company (Lin 2021-040) and the Announcement of Joincare Pharmaceutical Group Industry Co.,
    Ltd. on the Resolution of 2020 Annual General Meeting (Lin 2021-063).




                                                                                                                             119
      Pursuant to the Resolution on Increase of Ways to Input Proceeds for Equity Investment Projects respectively considered
      and approved at the 48th Meeting of the 7th Session of the Board on 10 June 2021, it was approved that the Company input
      investment by“provision of interest-free loans”to“Zhuhai Health Industry Base Construction Project”and“Haibin Pharma
      Pingshan Pharmaceutical Industrialization Base Project”. After adjustment, ways to input proceeds to“Zhuhai Health Industry
      Base Construction Project”and“Haibin Pharma Pingshan Pharmaceutical Industrialization Base Project”were to increase
      capital and provide interest-free loans, in which the amount of loans was limited to the net amount of proceeds not invested in
      equity investment projects as of the date of loan. The resolution was considered and approved at the 2021 second extraordinary
      general meeting convened by the Company on 29 June 2021. For details, see the Announcement of Joincare Pharmaceutical
      Group Industry Co., Ltd. on Increase of Ways to Input Proceeds for Equity Investment Projects disclosed by the Company
      (Lin 2021-070) and the Announcement of Joincare Pharmaceutical Group Industry Co., Ltd. on the Resolution of 2021 Second
      Extraordinary General Meeting of Joincare Pharmaceutical Group Industry Co., Ltd. (Lin 2021-081).

      Pursuant to the Resolution on the Temporary Replenishment of Working Capital with Idle Proceeds considered and approved
      at the 7th Meeting of the 8th Session of the Board of the Company on 30 December 2021, it was agreed that the Company
      temporarily replenished the working capital with no more than RMB 700 million of idle proceeds from 1 January 2022 to
      31 December 2022 on the premise of not affecting the progress of the equity investment projects, so as to improve the use
      eciency of proceeds and reduce nancial expenses of the Company.

      Pursuant to the“Resolution on Change of Certain Projects Invested with Proceeds”considered and approved at the 8th
      meeting of the 8th Session of the Board of the Company on 24 January 2022, given the facts that the“Zhuhai Health Industry
      Base Construction Project”has been postponed for several times for not meeting the conditions for commencement, and the
      market environment and the Company's business situation have changed, which resulted in changes in the project feasibility,
      that the Company has an urgent need of funds for R&D investment and other projects, and that other financing channels are
      time-consuming and costly, it was agreed that Zhuhai Health Industry Base Construction Project was changed to the New
      Product R&D Project, Haibin Pharma Pingshan Pharmaceutical Industrialization Base Expansion Project and the Information
      Platform Construction Project. The resolution was approved at the 2022 1st extraordinary general meeting of the Company
      on 11 February 2022. For details, see the“Announcement of Joincare Pharmaceutical Group Industry Co., Ltd. on Change of
      Certain Projects Invested with Proceeds”(Lin 2022-007).

      For details about deposit and actual use of proceeds in 2021, please refer to the Special Report of Joincare Pharmaceutical
      Group Industry Co., Ltd. on Deposit and Actual Use of Proceeds in 2021 disclosed by the Company on the website of
      Shanghai Stock Exchange (www.sse.com.cn) on 31 March 2022.


 2. Matters about share repurchase

 1) First share repurchases in 2021

      Pursuant to the Resolution on Share Repurchase Scheme by Way of Centralized bidding transactions and other resolutions
      considered and approved at the 41st Meeting of the 7th Session of the Board and the 2021 First Extraordinary General Meeting
      of the Company on 9 February 2021 and 25 February 2021, it was approved that the Company repurchased company shares by
      way of Centralized bidding transactions with its own funds; the total amount of repurchase funds should be no less than RMB
      350 million (inclusive) and no more than RMB 700 million (inclusive); the repurchase price should be no more than RMB
      20/share (inclusive); the repurchase term should be no more than 12 months from the date when the repurchase scheme was
      approved by the General Meeting of the Company. For the details, please see the Announcement of Joincare Pharmaceutical
      Group Industry Co., Ltd. on the Share Repurchase Scheme by Way of Centralized bidding transactions (Lin 2021-016) and the
      Repurchase Report of Joincare Pharmaceutical Group Industry Co., Ltd. on Share Repurchase by Way of Centralized bidding
      transactions (Lin 2021-027).

      On 9 March 2021, the Company initially repurchased 680,000 shares by way of Centralized bidding transactions, representing
      0.03% of total share capital of the Company. See the Announcement of Joincare Pharmaceutical Group Industry Co., Ltd. on
      Initial Share Repurchase by Way of Centralized bidding transactions (Lin 2021-028) for details.




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   As of 14 September 2021, the Company had actually repurchased 55,135,296 shares, representing 2.81% of the Company's
   total share capital (1,959,977,436 shares). The highest repurchase price was RMB 16.92/share, the lowest, RMB 10.80/share,
   and the average, RMB 12.69/share. The total amount of funds used was RMB 699,900,526.87 (including the handling fee).
   De-registration was completed on 16 September 2021. For details, see the“Announcement of Joincare Pharmaceutical Group
   Industry Co., Ltd. on Implementation Results of Share Repurchase and Share Changes”(Lin 2021-122).

2) Second share repurchases in 2021

   Pursuant to the Resolution on Share Repurchase Scheme by Way of Centralized bidding transactions and other resolutions
   considered and approved at the 6th Meeting of the 8th Session of the Board and the 2021 Fifth Extraordinary General Meeting
   of the Company on 6 December 2021 and 23 December 2021, it was approved that the Company repurchased company
   shares by way of Centralized bidding transactions with its own funds; the total amount of repurchase funds should be no less
   than RMB 300 million (inclusive) and no more than RMB 600 million (inclusive); the repurchase price should be no more
   than RMB 15/share (inclusive); the repurchase term should be no more than 12 months from the date when the repurchase
   scheme was approved by the General Meeting of the Company. For the details, please see the Announcement of Joincare
   Pharmaceutical Group Industry Co., Ltd. on the Share Repurchase Scheme by Way of Centralized bidding transactions (Lin
   2021-145) and the Repurchase Report of Joincare Pharmaceutical Group Industry Co., Ltd. on Share Repurchase by Way of
   Centralized bidding transactions (Lin 2022-002).

   On 20 January 2022, the Company initially repurchased 785,992 shares by way of Centralized bidding transactions,
   representing 0.04% of total share capital (1,907,727,908 shares) of the Company. The aggregate amount of funds used for the
   repurchase was RMB 9.981 million (including the transaction costs). See the Announcement of Joincare Pharmaceutical Group
   Industry Co., Ltd. on Initial Share Repurchase by Way of Centralized bidding transactions (Lin 2022-004) for details.

   As of 11 March 2022, the Company initially repurchased 19,195,871 shares by way of Centralized bidding transactions,
   representing 1.01% of total share capital (1,907,727,908 shares) of the Company. The aggregate amount of funds used for the
   repurchase was RMB229.98 million (including the transaction costs). See the Announcement of Joincare Pharmaceutical Group
   Industry Co., Ltd. on the Repurchase of Total Share Capital to 1% and the Repurchase Progress (Lin 2022-022) for details.


3. Non-public issuance of shares

   Resolutions in Relation to the 2020 Non-public Issuance of Shares were considered and approved at the 29th Meeting of the
   7th Session of the Board and the 24th Meeting of the 7th Session of the Supervisory Committee of the Company on 12 July
   2020. No more than 169,350,000 shares (inclusive) were planned to be issued through non-public issuance; Hillhouse Capital
   Management PTE. LTD. (Hillhouse Capital) planned to subscribe for all of those shares with no more than RMB2,172,760,500
   through“Hillhouse Capital Management PTE. LTD.-China Value Fund”under its management. The Company entered into
   the Share Subscription Agreement Valid with Conditions between Joincare Pharmaceutical Group Industry Co., Ltd. and
   Hillhouse Capital Management PTE. LTD. and the Strategic Cooperation Agreement Valid with Conditions between Joincare
   Pharmaceutical Group Industry Co., Ltd. and Hillhouse Capital Management PTE. LTD. with Hillhouse Capital. See the
   Announcement of Joincare Pharmaceutical Group Industry Co., Ltd. on Attraction of Strategic Investors and Execution
   of Strategic Cooperation Agreement (Lin 2020-089) and the Plan for 2020 Non-public Issuance of Shares of Joincare
   Pharmaceutical Group Industry Co., Ltd. disclosed by the Company on 13 July 2020. The said resolut ions on non-public
   issuance of shares were approved at the 2020 Second Extraordinary General Meeting of the Company on 29 July 2020.

   Pursuant to the Resolution on Termination of Matters regarding 2020 Non-public Issuance of Shares and the Resolution
   on Termination Agreement on Share Subscription Agreement and Strategic Cooperation Agreement Valid with Conditions
   between the Company and Subscribers considered and approved at the 41st Meeting of the 7th Session of the Board and the
   32nd Meeting of the 7th Session of the Supervisory Committee of the Company on 9 February 2021, it was approved that the
   Company terminated the non-public issuance of shares. See the Announcement of Joincare Pharmaceutical Group Industry
   Co., Ltd. on Termination of Matters regarding 2020 Non-public Issuance of Shares and the Termination Agreement on Share
   Subscription Agreement Valid with Conditions and Strategic Cooperation Agreement Valid with Conditions (Lin 2021-015)
   disclosed by the Company on 10 February 2021.



                                                                                                                           121
 4. Reorganization of LivzonBio

      Pursuant to the Resolution on Reorganization of Shareholding Structures of LivzonBio and Other Subsidiaries was considered
      and approved at the 36th Meeting of the 7th Session of the Board of the Company on 4 December 2020, the Company, Livzon
      Group and other trading parties agreed to reorganize shareholding structures of the subordinates of Livzon Cayman, took
      Zhuhai Livzon Biotechnology Co., Ltd. as the controlling platform company of the subordinates of Livzon Cayman at home
      and abroad so as to optimize shareholding structures of the subordinates of Livzon Cayman for the purpose of financing
      at home and abroad. Original multiple indirect shareholding structures were adjusted to direct shareholding by parties; the
      Reorganization Framework Agreement was jointly signed. The said resolutions were considered and approved at the 2020
      Fourth Extraordinary General Meeting on 21 December 2020. See the Announcement of Joincare Pharmaceutical Group
      Industry Co., Ltd. on Reorganization of Shareholding Structures of the Controlling Subsidiary of Livzon Group (Lin 2020-159)
      disclosed by the Company on 5 December 2020 for details.

      Pursuant to the Equity Transfer Agreement between the Company, Livzon Group and Livzon HK on 11 January 2021, the
      Company and Livzon Group agreed to respectively acquire 49% and 51% equity interest in LivzonBio from Livzon HK.
      Pursuant to the Capital Injection Agreement among the Company, Livzon Group, Lisheng Juyuan, and LivzonBio on the
      same day, the Company, Livzon Group and Lisheng Juyuan jointly injected capital to LivzonBio. The registered capital of
      LivzonBio was increased from RMB250,000,000 to RMB666,666,667. The capital injection was completed with filing of
      industrial and business change registration on 15 January 2021. After the change, LivzonBio was respectively owned by the
      Company, Livzon Group and Lisheng Juyuan as to 44.10%, 45.90% and 10.00% equity interest, respectively.

      Pursuant to the Capital Injection Agreement among the Company, Livzon Group, Lisheng Juyuan, YF, Livzon HK, Livzon
      MAB, Kadi, and LivzonBio on 18 January 2021, Livzon Group and YF jointly injected capital to LivzonBio. The capital
      injection was completed with filing of industrial and business change registration on 5 February 2021. After the change, the
      registered capital of LivzonBio was increased from RMB666,666,667 to RMB889,023,284. LivzonBio was owned by the
      Company, Livzon Group, YF, and Lisheng Juyuan as to 33.07%, 51.00%, 8.43% and 7.50% equity interest, respectively.
      Pursuant to the Equity Transfer Agreement between LivzonBio and Livzon HK on 18 January 2021, Livzon HK agreed to
      transfer and LivzonBio agreed to acquire 100% equity interest of Livzon MAB. The equity transfer was completed with ling
      of industrial and business change registration on 3 February 2021. After the change, Livzon MAB was directly owned by
      LivzonBio as to 100.00% equity interest.

      On 27 January 2021, LivzonBio and Livzon Cayman entered into an equity transfer agreement, pursuant to which Livzon
      Cayman agreed to transfer and LivzonBio agreed to acquire 100% equity interest of Livzon HK. The equity transfer was
      completed on 16 April 2021. After the change, Livzon HK was directly owned by LivzonBio as to 100.00% equity interest.

      On 25 February 2021, each of Livzon International, YF and Joincare BVI issued a repurchase letter to Livzon Cayman.
      Pursuant to which, (1) each of Livzon International and YF agreed that Livzon Cayman could repurchase 24,574,830 ordinary
      shares and 12,500,000 preferred A shares held by them respectively at a consideration of USD98,299,320 in RMB equivalent
      (i.e. RMB637,421,940.54) and USD50,000,000 in RMB equivalent (i.e. RMB324,225,000), respectively; (2) each of Livzon
      International and Joincare BVI agreed that Livzon Cayman could repurchase 50,999,999 ordinary shares and 49,000,000
      ordinary shares held by them respectively at a consideration of RMB306,038,709 and RMB294,037,191 respectively. As at 26
      February 2021, Livzon Cayman repurchased a total of 137,074,829 shares in issue and paid the corresponding consideration of
      the share repurchases to Livzon International, YF and Joincare BVI, respectively. The above share repurchases were completed
      and Livzon Cayman only preserved 1 issued ordinary share, which was held by Livzon International. Livzon Cayman is
      directly owned by Livzon International as to 100.00% equity interest, and the relevant registration of Livzon Cayman will be
      canceled.

      For specific information on the reorganization of the shareholding structures, please refer to relevant announcements
      respectively disclosed by the Company on 5 December 2020, 12 January 2021, 19 January 2021, 28 January 2021, 16 February
      2021, and 13 May 2021 (Announcement No.: Lin 2020-159, Lin 2021-007, Lin 2021-009, Lin 2021-012, Lin 2021-023, and
      Lin 2021-061).




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5. Livzon Group's plan to spin o Livzon Diagnostics for A-share listing

   On 7 August 2020, the Board of Directors of Livzon Group, a majority-controlled subsidiary of the Company, considered and
   approved the proposal to spin o its subsidiary Zhuhai Livzon Diagnostics Inc. (hereinafter referred to as Livzon Diagnostics)
   for A-share listing (hereinafter referred to as spin-off listing). Livzon Diagnostics is mainly engaged in the R&D, production
   and sale of diagnostic reagents and equipment. As at the end of the Reporting Period, Livzon Group held approximately
   39.425% of shares of Livzon Diagnostics. After completion of this spin-off, the shareholding structure of Livzon Group will
   remain unchanged, and Livzon Group will still maintain control over Livzon Diagnostics. For more details, please see“the
   Suggestive Announcement of Joincare Pharmaceutical Group Industry Co., Ltd. on Livzon Group's Planned Spin-off of Its
   Subsidiary Livzon Diagnostics for A-share Listing”(Lin 2020-106).

   On 16 October 2020, the Stock Exchange of Hong Kong Limited (hereinafter referred to as SKEX) agreed to Livzon Group's
   spin-off listing, and agreed to exempt the group from the applicable regulations concerning the assured entitlement related to
   the spin-o listing. For details, see the Announcement of Joincare Pharmaceutical Group Industry Co., Ltd. on the progress of
   Livzon Group's Planned Spin-o of Its Subsidiary Livzon Diagnostics for A-share Listing (Lin 2020-131).

   Livzon Diagnostics would go spin-off listing on the ChiNext Board of Shenzhen Stock Exchange pursuant to the Resolution
   on the Spin-off of the Subsidiary Zhuhai Livzon Diagnostics Inc. to Go Listing on the ChiNext Board of Shenzhen Stock
   Exchange considered and approved at the Board meeting of Livzon Group on 23 October 2020. For details, see the
   Announcement of Joincare Pharmaceutical Group Industry Co., Ltd. on the progress of Livzon Group's Planned Spin-o of Its
   Subsidiary Livzon Diagnostics for A-share Listing (Lin 2020-134).

   The spin-o listing of Livzon Diagnostics was approved at the 2020 4th extraordinary general meeting of Livzon Group on 20
   November 2020, and was registered with Guangdong Securities Regulatory Bureau for pre-listing tutoring in November 2020.
   As of the disclosure date of this report, Livzon Diagnostics has submitted the ve issues of reports on progress of the tutoring.
   As of the disclosure date of this report, Livzon Diagnostics has not submitted any application to or registered with Shenzhen
   Stock Exchange or any relevant Chinese regulatory authorities other than those progresses listed above.




                                                                                                                              123
      Chapter 7
      Changes in Equity and Shareholders


 I Changes in share capital

 (I) Table of changes in shares
 1. Table of changes in shares

                                                        Before the current change         Increase/decrease (+, -) due to the current change              After the current change
                                                                                                            Conversion
                                                                                                Issuance
                                                                       Percentage Issuance of                 of capital                                               Percentage
                                                            Number                              of bonus                       Others          Subtotal     Number
                                                                             (%) new shares                  reserve to                                                       (%)
                                                                                                  shares
                                                                                                           share capital
      I. Shares subject to selling restrictions                   0            0           0          0               0              0               0             0            0
      1. Shares held by state government
      2. Shares held by state-owned entities
      3. Shares held by other domestic holders
      Of which: Shares held by domestic
      non-state-owned entities
      Shares held by domestic natural persons
      4. Shares held by foreign holders
      Including: Shares held by foreign entities
      Shares held by foreign natural persons
      II. Shares not subject to selling restrictions   1,952,780,764         100 10,082,440           0               0 -55,135,296 -45,052,856 1,907,727,908                 100
      1. Ordinary shares denominated in Renminbi 1,952,780,764               100 10,082,440           0               0 -55,135,296 -45,052,856 1,907,727,908                 100
      2. Domestically listed foreign shares
      3. Overseas listed foreign shares
      4. Others
      III. Total number of shares                      1,952,780,764         100 10,082,440           0               0 -55,135,296 -45,052,856 1,907,727,908                 100


 2. Explanations on changes in shares
    √ Applicable □ N/A

      The number of exercisable options during the second exercise period of the rst grant under the 2018 Share Options Incentive
      Scheme of the Company was 8,001,000, and the exercise period was from 21 December 2020 to 20 December 2021. The
      number of exercisable options during the third exercise period was 7,263,000, and the exercise period was from 21 December
      2021 to 20 December 2022 The number of exercisable options during the rst exercise period of the reserved grant under the
      2018 Share Options Incentive Scheme of the Company was 3,545,000, and the exercise period was from 23 September 2020
      to 22 September 2021. The number of exercisable options during the second exercise period was 2,935,000, and the exercise
      period was from 23 September 2021 to 22 September 2022. Options are exercised in an active way. During the Reporting
      Period, the number of options cumulatively exercised and completing share transfer registration for grants under the 2018
      Share Options Incentive Scheme of the Company was 10,082,440.

      From 25 February 2021 to 24 February 2022, the Company expects to buy back at a price of not more than RMB 20 yuan/
      share, with a total repurchase amount of not less than RMB 350 million (inclusive) and not more than RMB 700 million
      (inclusive). The shares bought back this time will be used to reduce the registered capital of the Company. As of 14 September
      2021, the Company has bought back 55,135,296 shares through centralized bidding, and canceled 55,135,296 shares bought
      back in Shanghai Branch of China Securities Depository and Clearing Corporation Limited on 16 September 2021.




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3. The inuence of changes in shares on nancial indicators such as earnings per share and net assets per share in the most recent
   year and the most recent reporting period (if applicable)
   □ Applicable √ N/A

4. Other information disclosed as the Company deems necessary or required by the securities regulatory authority
   □ Applicable √ N/A


(II) Changes in shares subject to selling restrictions
    □ Applicable √ N/A


II Issuance and listing of securities

(I) Securities issued during the Reporting Period
    □ Applicable √ N/A

    Explanations on securities issuance during the Reporting Period (list separately bonds with different interest rates during the
    duration):
    □ Applicable √ N/A


(II) Changes in total number of shares, shareholding structure, and structure of assets and liabilities of the Company
    □ Applicable √ N/A


(III) Outstanding shares granted under the employee share ownership scheme
    □ Applicable √ N/A


III Information on shareholders and the de facto controller

(I) Total number of shareholders

     Total number of shareholders of ordinary shares as of the end of the Reporting Period                                109,269
     Total number of shareholders of ordinary shares as of the end of the month immediately prior
                                                                                                                          104,600
     to the publish date of this annual report




                                                                                                                               125
 (II) Shares held by top 10 shareholders and top 10 holders of tradable shares (shares without selling restrictions) as of
      the end of the Reporting Period
                                                                                                                                                         Unit: shares
                                                                Shareholdings of the Top 10 shareholders
                                                 Change during Number of shares                   I. Number of shares Pledge, mark or lock-up
      Name of shareholder                                                            Percentage                                               Nature of
                                                  the Reporting held at the End of                held without selling
      (Full name)                                                                           (%)                        Share status Number shareholder
                                                         Period         the Period                        restrictions
                                                                                                                                                     Domestic
      Shenzhen Baiyeyuan Investment Co.,
                                                               0         895,653,653          46.95                     0      Pledge     95,679,725 non-state
      Ltd. * ( 深圳市百业源投资有限公司 )
                                                                                                                                                     owned entity
      Hong Kong Securities Clearing
                                                       -2,253,722          91,961,426          4.82                     0     Unknown                  Unknown
      Company Limited
      Might Seasons Limited                                    0           71,859,334          3.77                     0     Unknown                  Foreign entity
      108 portfolio of national social
                                                       -4,570,119          12,272,021          0.64                     0     Unknown                  Unknown
      security fund
      Huaxia Life Insurance Co., Ltd. -
                                                       9,112,618            9,112,618          0.48                     0     Unknown                  Unknown
      Equity fund
      16011 portfolio of basic endowment
                                                   -11,977,669              9,050,234          0.47                     0     Unknown                  Unknown
      insurance fund
      Bosera Funds Management Co., Ltd. -
                                                   -11,266,700              8,732,946          0.46                     0     Unknown                  Unknown
      419 portfolio of social security funds
                                                                                                                                                       Domestic
      He Zhong                                         3,062,424            7,850,024          0.41                     0     Unknown
                                                                                                                                                       natural person
      Agricultural Bank of China Limited
      - Fullgoal CSI 500 Index Enhanced                4,186,892            5,757,424          0.30                     0     Unknown                  Unknown
      Securities Investment Fund (LOF)
      Agricultural Bank of China Limited
      - CSI 500 Exchange Traded Index                    -95,308            5,397,294          0.28                     0     Unknown                  Unknown
      Securities Investment Fund
                                                   Shareholdings of the Top 10 shareholders without selling restrictions
                                                                    Number of tradable shares held                      Class and number of shares
      Name of shareholder
                                                                       without selling restrictions                         Class                            Number
      Shenzhen Baiyeyuan Investment Co., Ltd. *
                                                                                        895,653,653     Ordinary shares denominated in Renminbi          895,653,653
      (深圳市百业源投资有限公司 )
      Hong Kong Securities Clearing Company Limited                                      91,961,426     Ordinary shares denominated in Renminbi           91,961,426
      Might Seasons Limited                                                              71,859,334     Ordinary shares denominated in Renminbi           71,859,334
      108 portfolio of national social security fund                                     12,272,021     Ordinary shares denominated in Renminbi           12,272,021
      Huaxia Life Insurance Co., Ltd. - Equity fund                                       9,112,618     Ordinary shares denominated in Renminbi             9,112,618
      16011 portfolio of basic endowment insurance fund                                   9,050,234     Ordinary shares denominated in Renminbi             9,050,234
      Bosera Funds Management Co., Ltd. - 419 portfolio of
                                                                                          8,732,946     Ordinary shares denominated in Renminbi            8,732,946
      social security funds
      He Zhong                                                                            7,850,024     Ordinary shares denominated in Renminbi            7,850,024
      Agricultural Bank of China Limited - Fullgoal CSI 500
                                                                                          5,757,424     Ordinary shares denominated in Renminbi            5,757,424
      Index Enhanced Securities Investment Fund (LOF)
      Agricultural Bank of China Limited - CSI 500
                                                                                          5,397,294     Ordinary shares denominated in Renminbi            5,397,294
      Exchange Traded Index Securities Investment Fund
                                                                    As at the end of the Reporting Period, the special repurchase account of the Company (special
      Notes on the special repurchase account among the
                                                                    securities repurchase account of Joincare Pharmaceutical Group Industry Co., Ltd.) owned
      Top 10 shareholders
                                                                    17,459,813 shares in total, accounting for 0.92%.




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                                                                                                                                            2021


     Description of the above shareholders involved in
     entrustment/entrusted voting right and waiver of    Not applicable
     voting right
                                                         There was no connection or acting-in-concert relationship between Shenzhen Baiyeyuan
     Description of connection or acting-in-concert
                                                         Investment Co., Ltd., a controlling shareholder of the Company, and other shareholders; whether
     relationship of the above shareholders
                                                         there is connection or acting-in-concert relationship among other shareholders is unknown.


     Number of shares held by the Top 10 shareholders with selling restrictions and the description of the selling restrictions
     □ Applicable √ N/A


(III) Strategic investors or general legal persons who became top 10 shareholders as a result of allotment of new shares
     □ Applicable √ N/A


IV Information on the Controlling shareholder and the de facto controller

(I) Information on the Controlling shareholder
 1   Legal person
     √ Applicable □ N/A


     Name                                                Shenzhen Baiyeyuan Investment Co., Ltd. * ( 深圳市百业源投资有限公司 )
     Person in charge of the unit or legal
                                                         Zhu Baoguo
     representative
     Date of incorporation                               January 21, 1999
                                                         Investment in industry, domestic commerce, and material supply and
     Principal business
                                                         marketing industry
     Equity held in other domestic and overseas          Except for the daily trading of securities assets in the secondary market,
     listed companies during the Reporting               Baiyeyuan did not hold or participate in the equity of other domestic and
     Period                                              overseas listed companies during the Reporting Period.
     Others                                              Not applicable


 2   Natural person
     □ Applicable √ N/A

 3   Special statement if the Company does not have a controlling shareholder
     □ Applicable √ N/A

 4   Statement on changes in controlling shareholders during the Reporting Period
     □ Applicable √ N/A

 5   The block diagram describing controlling shareholders' ownership of and control over the Company
     √ Applicable □ N/A

     See the“Block diagram showing the property rights and control relationship between the Company and its de facto
     shareholders”in this chapter.




                                                                                                                                                      127
 (II) Information on the De facto controller
 1    Legal person
      □ Applicable √ N/A

 2    Natural person
      √ Applicable □ N/A


      Name                                               Zhu Baoguo
      Nationality                                        China
      Hold the right of residence in other
                                                         No
      countries or regions or not
      Main occupation and position                       Chairman of the Company and Livzon Group
      Domestic and overseas listed companies             Except for the Company and Livzon Group, Mr. Zhu Baoguo has never
      controlled in the past 10 years                    controlled any other domestic and overseas listed companies.


 3    Special statement if the Company does not have a de facto controller
      □ Applicable √ N/A

 4    Statement on change of control of the Company during the Reporting Period
      □ Applicable √ N/A

 5    The block diagram describing de facto controllers' ownership of and control over the Company
      √ Applicable □ N/A


                                         Zhu Baoguo                              Liu Guangxia


                                                   90%                                  10%


                                                Shenzhen Baiyeyuan Investment Co., Ltd.


                                                                      46.95%


                                             Joincare Pharmaceutical Group Industry Co., Ltd.


 6    The De facto controller controls the Company through trust or other asset management methods
      □ Applicable √ N/A


(III) Other information on the controlling shareholder and the de facto controllers
      □ Applicable √ N/A


 V The cumulative number of shares pledged by controlling shareholders or the largest
   shareholder of the Company and their persons acting in concert accounts for more than
   80% of the shares held by them in the Company
      □ Applicable √ N/A


VI Other corporate shareholders holding more than 10% shares
      □ Applicable √ N/A


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VII Explanation on restrictions on share selling
   □ Applicable √ N/A


VIII Information on implementation of share repurchases plans during the Reporting Period
   √ Applicable □ N/A
                                                                                                 Unit: 10,000 Yuan Currency: RMB
                                                       Plan on share repurchase by           Plan on share repurchase by
    Name of share repurchase plan
                                                       centralized bidding                   centralized bidding
    Disclosure date of share repurchase plan           10 February 2021                      7 December 2021
    Number of shares to be repurchased and its
                                                       0.89~1.79                             1.05~2.10
    percentage in total share capital (%)
    Proposed repurchase amount                         35,000~70,000                         30,000~60,000
                                                       12 months after the date when the     12 months after the date when the
    Proposed repurchase period                         share repurchase plan is approved     share repurchase plan is approved
                                                       at the general meeting                at the general meeting
                                                       To reduce registered capital of the   To reduce registered capital of the
    Purpose of repurchase
                                                       Company                               Company
    Repurchased number (shares)                        55,135,296                            0
    Percentage of repurchased shares in the target
                                                       Not applicable                        Not applicable
    shares under share incentive scheme (%) (if any)
    The progress of the Company's reduction of
                                                       Not applicable                        Not applicable
    repurchased shares by centralized bidding
                                                       On 16 September 2021, 55,135,296
    Remarks                                            repurchased shares completed
                                                       cancellation.




                                                                                                                              129
      Chapter 8
      Information on Preferred Shares

      □ Applicable √ N/A




130
  Chapter 9
  Information on Bonds


I Corporate bonds, debentures and debt financing instruments issued by non-financial entities
  □ Applicable √ N/A


II Convertible corporate bonds
  □ Applicable √ N/A




                                                                                            131
      Chapter 10
      Financial Statements


 I Auditor's report
      √ Applicable □ N/A



                                                                                                    Z.T.S.Zi (2022) No. 442A005270


      To all shareholders of Joincare Pharmaceutical Group Industry Co., Ltd.:


 I. Auditor's Opinion
      We have audited the nancial statements of Joincare Pharmaceutical Group Industry Co., Ltd. (the“Group”), which comprise
      the Consolidated and Company balance sheet as at 31 December 2021, and the Consolidated and Company income statement,
      the Consolidated and Company cash flow statement, the Consolidated and Company statement of changes in shareholders'
      equity for the year 2021, and notes to the nancial statements.

      In our opinion, the accompanying financial statements have been prepared in compliance with the Accounting Standards for
      Enterprises in all material aspects, and give a truthful and fair view of the Consolidated and Company nancial position of the
      Group as at 31 December 2021, and of its Consolidated and Company nancial performance and cash ows for the year 2021.


 II. Basis for the Formation of Auditor's Opinion
      We conducted our audit in accordance with Auditing Standards for CPAs of China (the“Auditing Standards”). Our
      responsibilities under those standards are further described in the“Auditor's responsibilities for the audit of the financial
      statements”section of our report. We are independent of the Group in accordance with China Code of Ethics for Certified
      Public Accountants (the“Code”), and we have fulfilled our other ethical responsibilities in accordance with the Code. We
      believe that the audit evidence we have obtained is sucient and appropriate to provide a basis for our opinion.


 III. Key Audit Matters
      Key audit matters are those matters that, in our professional judgment, were of most significance in our audit of the financial
      statements of the current period. These matters were addressed in the context of our audit of the financial statements as a
      whole, and in forming our opinion thereon, and we do not provide a separate opinion on these matters.

 (I) Revenue recognition

      Further disclosed in paragraph 28 under Note 3 to the nancial statements and paragraph 43 under Note 5.

 1. Key audit matter

      In 2021, the Group generated operating revenues of RMB15,746.62 million from the principal businesses. We identified
      revenue recognition as a key audit matter due to the materiality of revenue to the nancial statements as a whole and the risk of
      material misstatement as to whether revenue is real and accurately accounted for in the appropriate accounting period.

 2. How our audit addressed the key audit matter

      (1) We obtained an understanding of and assessed the Company management's design and operating effectiveness of key
          internal controls over revenue recognition.
      (2) We obtained the contracts signed between the Company and its customers and veried the key terms of the contracts, such
          as shipment and acceptance, payment and settlement, exchange and return policies.




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     (3) We inquired about the business registration information of the Company's customers and asked relevant personnel of
         the Company in order to confirm whether there was an affiliated relationship between the Company and its customers;
         obtained an understanding of the reasons for customer changes and contract performance among others; counted and
         analyzed end sales of products purchased by selected customers from the Company based on the business system of the
         Company's directly connected customers.
     (4) We obtained records of returns and exchanges in the Company's business system and checked them to confirm whether
         there were signicant abnormalities that aected revenue recognition.
     (5) We selected samples to check contracts, purchase orders, shipping documents, transportation documents, bookkeeping
         vouchers, payback documents, and periodic reconciliation letters, and performed external confirmation procedures on
         major customer sales and accounts receivable.
     (6) The procedures of income analysis for the rationality of income changes are based on product category and factors such as
         market trends, industry trends, business expansion; and the income analysis would be combined with market data collected
         by third-party consulting companies.
     (7) We sampled sales revenue transactions around the balance sheet date, reviewed sales contracts, purchase orders, shipping
         documents, transportation documents, and bookkeeping vouchers, and evaluated whether revenues were recorded in the
         appropriate accounting period.
(II) Allowance for bad debts on accounts receivable

    Further disclosed in paragraph 10 under Note 3 to the nancial statements and paragraph 4 under Note 5.

1. Key audit matter

    As of 31 December 2021, the Group's ending balance of accounts receivable as reported in the consolidated balance sheet
    was RMB 2,926.10 million and the allowance for bad debts was RMB 72.44 million which were material to the financial
    statements as a whole. The management is required to apply significant accounting estimates and judgments in assessing the
    expected recoverable amount of accounts receivable, which could have a material impact on the financial statements if they
    were not collected on schedule or uncollectible resulting in a bad debt loss. Therefore, we identied allowance for bad debts on
    accounts receivable as a key audit matter.

2. How our audit addressed the key audit matter

    (1) We obtained an understanding of and assessed the management's design and operating eectiveness of key internal controls
        over the management of accounts receivable.
    (2) We obtained an understanding of the basis and process of recognizing the expected credit loss ratio and the key parameters
        and assumptions applied in the expected credit loss model, including the basis for grouping accounts receivable based on
        customers' credit risk characteristics and the historical migration rate data indicated in the expected loss ratio; evaluated
        whether the expected credit loss ratio was set by taking into account and was appropriately adjusted for current economic
        conditions and forward-looking information, and assessed the reasonableness of the estimate of the allowance for bad
        debts.
    (3) We obtained a schedule of allowance for bad debts on accounts receivable and checked whether the allowance method was
        implemented in accordance with the allowance policy for bad debts; and recalculated the amount of allowance for bad
        debts to check the accuracy.
    (4) We analyzed the ratio of the ending balance of allowance for bad debts to accounts receivable and compared the allowance
        for bad debts in the previous period with the actual amount incurred, and analyzed whether the allowance for bad debts on
        accounts receivable was adequate.
    (5) We analyzed the aging of accounts receivable and the creditworthiness of customers, and evaluated the reasonableness of
        the allowance for bad debts on accounts receivable through audit procedures such as audit confirmation and post-period
        recovery check.




                                                                                                                                133
 IV. Other Information
      The Group's management (the“Management”) is responsible for the other information. The other information comprises
      the information disclosed in 2021 Annual Report of the Group but does not include the financial statements and our auditor's
      report thereon.

      Our opinion on the financial statements does not cover the other information and we do not express any form of assurance
      conclusion thereon.

      In connection with our audit of the financial statements, our responsibility is to read the other information and, in doing so,
      consider whether the other information is materially inconsistent with the financial statements or our knowledge obtained in
      the audit or otherwise appears to be materially misstated.

      If, based on the work we have performed, we conclude that there is a material misstatement of this other information, we are
      required to report that fact. We have nothing to report in this regard.


 V. Management's and Governance Level's Responsibility for the Financial Statements
      The Management of the Group is responsible for the preparation of the financial statements that give a truthful and fair view
      in accordance with the Accounting Standards for Enterprises, and for design, implementation and maintenance of internal
      controls necessary to enable the preparation of financial statements that are free from material misstatement, whether due to
      fraud or error.

      In preparing the financial statements, the Management is responsible for assessing the Group's ability to continue as a going
      concern, disclosing, as applicable, matters related to going concern and using the going concern basis of accounting unless the
      Management of the Group either intends to liquidate the Group or to cease operations or has no realistic alternative but to do so.

      The Governance level is responsible for overseeing the Group's nancial reporting process.


 VI. CPA's Responsibilities for the Audit of the Financial Statements
      Our objectives are to obtain reasonable assurance about whether the financial statements as a whole are free from material
      misstatement, whether due to fraud or error, and to issue an auditor's report that includes our opinion. Reasonable assurance is
      a high level of assurance, but is not a guarantee that an audit conducted in accordance with the Auditing Standards will always
      detect a material misstatement when it exists. Misstatements can arise from fraud or error and are generally considered material
      if, individually or in the aggregate, they could reasonably be expected to influence the economic decisions of users taken on
      the basis of the nancial statements.

      As part of an audit in accordance with the Auditing Standards, we exercise professional judgment and maintain professional
      skepticism throughout the audit. We also:

      (1) Identify and assess the risks of material misstatement of the nancial statements, whether due to fraud or error, design and
          perform audit procedures responsive to those risks, and obtain audit evidence that is sucient and appropriate to provide a
          basis for our opinion. The risk of not detecting a material misstatement resulting from fraud is higher than for one resulting
          from error, as fraud may involve collusion, forgery, intentional omissions, misrepresentations, or the override of internal
          control.
      (2) Obtain an understanding of internal control relevant to the audit in order to design appropriate audit procedures.
      (3) Evaluate the appropriateness of accounting policies used and the reasonableness of accounting estimates and related
          disclosures made by the Management.
      (4) Conclude on the appropriateness of the Management's use of the going concern basis of accounting and, based on the audit
          evidence obtained, whether a material uncertainty exists related to events or conditions that may cast significant doubt
          on the Group's ability to continue as a going concern. If we conclude that a material uncertainty exists, we are required
          to draw attention in our auditor's report to the related disclosures in the financial statements or, if such disclosures are
          inadequate, to modify our opinion. Our conclusions are based on the audit evidence obtained up to the date of our auditor's



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                                                                                                                    2021


    report. However, future events or conditions may cause the Group to cease to continue as a going concern.
(5) Evaluate the overall presentation, structure and content of the financial statements, and whether the financial statements
    represent the underlying transactions and events in a manner that achieves fair presentation.
(6) Obtain sufficient appropriate audit evidence regarding the financial information of the entities or business activities
    within the Group to express an opinion on the financial statements. We are responsible for the direction, supervision and
    performance of the group audit, and remain solely responsible for our audit opinion.

We communicate with the Governance level regarding the planned scope and timing of the audit and signicant audit ndings,
including any signicant deciencies in internal control that we identify during our audit.

We also provide the Governance level with a statement that we have complied with relevant ethical requirements regarding
independence and communicate with it all relationships and other matters that may reasonably be thought to bear on our
independence, and where applicable, related safeguards.

In our communication with the Governance level, we identify key audit matters which are those matters of most significance
in our audit of the financial statements of the current period. We disclose these matters in our auditor's report unless public
disclosure of such matters is prohibited by laws or regulations, or in rare cases where we determine not to communicate a
matter in our auditor's report if we reasonably expect that the negative consequences of communicating it in our auditor's
report would outweigh the benets in the public interest.




                                                               Certied Public Accountants           Wang Ying
      Grant Thornton (Special General Partnership)             (The partner in charge of the auditing service project)

                     Beijing,  China                           Certied Public Accountants           Wang Qilai

                                                               March 29, 2022




                                                                                                                          135
II Financial statements
                                          Consolidated Balance Sheet
                                                   31 December 2021

Prepared by: Joincare Pharmaceutical Group Industry Co., Ltd.                              Unit: Yuan Currency: RMB
Item                                                            Note   31 December 2021            31 December 2020
Current assets:
Monetary funds                                                  V.1    11,729,230,390.98            12,289,098,613.19
Financial assets held for trading                               V.2      184,638,344.31                28,328,748.72
Bill receivable                                                 V.3     1,977,286,022.02             1,343,013,818.54
Accounts receivable                                             V.4     2,853,655,551.54             2,447,406,222.52
Receivables nancing
Prepayments                                                     V.5      369,232,546.29               209,926,040.57
Other receivables                                               V.6       88,053,825.12               177,240,162.81
In which: Interests receivable                                               365,873.64
Dividends receivable
Inventories                                                     V.7     2,078,944,387.68             1,831,509,012.27
Contract assets
Held-for-sale assets
Non-current assets due within one year                          V.8          317,381.23                19,934,376.07
Other current assets                                            V.9       83,986,214.37                58,098,049.20
Total current assets                                                   19,365,344,663.54            18,404,555,043.89
Non-current assets:
Debt investment
Other debt investment
Long-term receivables                                           V.10         266,904.13                   584,284.36
Long-term equity investment                                     V.11    1,419,349,454.84              628,279,599.73
Other equity instrument investment                              V.12    1,408,882,377.42             1,576,391,663.13
Other non-current nancial assets
Investment properties                                           V.13        6,191,475.43                 6,191,475.43
Fixed assets                                                    V.14    4,839,005,169.81             4,380,285,156.93
Construction in progress                                        V.15     742,998,743.75               648,478,042.42
Productive biological assets
Oil & gas assets
Right-of-use assets                                             V.16      46,774,759.69                18,030,132.69
Intangible assets                                               V.17     456,782,094.80               468,087,916.05
Development expenses                                            V.18     786,993,435.71               399,119,603.78
Goodwills                                                       V.19     614,468,698.73               614,468,698.73
Long-term prepaid expenses                                      V.20     200,715,740.93               170,049,601.98
Deferred income tax assets                                      V.21     552,542,866.71               468,898,469.23
Other non-current assets                                        V.22     663,584,003.80               373,557,910.72
Total non-current assets                                               11,738,555,725.75             9,752,422,555.18
Total assets                                                           31,103,900,389.29            28,156,977,599.07
Current liabilities:
Short-term loans                                                V.23    2,518,484,835.09             2,110,942,804.06
 Financial liabilities held for trading                         V.24         143,302.24                       212.07
Notes payable                                                   V.25    1,582,386,767.93             1,087,759,353.31
Accounts payable                                                V.26     871,553,210.51               832,632,206.53
Receipts in advance
Contract liabilities                                            V.27     234,140,702.29               133,422,354.03
Payroll payable                                                 V.28     475,430,823.20               476,521,798.51



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Item                                                                 Note                    31 December 2021              31 December 2020
Taxes payable                                                        V.29                      270,618,183.41                 298,342,182.44
Other payables                                                       V.30                     3,292,407,989.79              2,847,688,065.59
In which: Interests payable
Dividends payable                                                                                 6,951,984.46                  8,418,590.50
Held-for-sale liabilities
Non-current liabilities due within one year                          V.31                       91,576,066.33                   8,539,077.05
Other current liabilities                                            V.32                       15,626,224.29                   6,267,034.79
Total current liabilities                                                                     9,352,368,105.08              7,802,115,088.38
Non-current liabilities:
Long-term loans                                                      V.33                      826,780,252.78                 360,324,027.48
Bonds payable
Lease liabilities                                                    V.34                       25,071,794.32                   9,817,780.04
Long-term payables
Long-term payroll payable
Estimated liabilities
Deferred income                                                      V.35                      433,543,352.40                 467,562,770.49
Deferred income tax liabilities                                      V.21                      208,525,905.39                 202,259,855.68
Other non-current liabilities                                        V.36                       78,000,000.00                  78,000,000.00
Total non-current liabilities                                                                 1,571,921,304.89              1,117,964,433.69
Total liabilities                                                                            10,924,289,409.97              8,920,079,522.07
Owner's equity (or shareholder's equity):
Paid-in capital                                                      V.37                     1,907,727,908.00              1,952,780,764.00
Other equity instruments
In which: Preferred shares
Perpetual debts
Capital reserve                                                      V.38                     2,265,357,311.92              2,533,288,674.28
Less: Treasury shares                                                V.39                      222,644,454.50                 253,637,154.50
Other comprehensive income                                           V.40                         5,387,545.97                116,300,559.28
Special reserve
Surplus reserve                                                      V.41                      640,821,179.08                 515,941,465.19
Undistributed prots                                                  V.42                     7,223,644,166.22              6,231,451,582.26
Total owner's equity (or shareholder's equity) attributable to the
                                                                                             11,820,293,656.69             11,096,125,890.51
parent company
Minority shareholder's equity                                                                 8,359,317,322.63              8,140,772,186.49
Total owner's equity (or shareholder's equity)                                               20,179,610,979.32             19,236,898,077.00
Total liabilities and owner's equity (or shareholder's equity)                               31,103,900,389.29             28,156,977,599.07

Person-in-charge of the Company:        Person-in-charge of the Company's accounting work:     Person-in-charge of the accounting department:
Zhu Baoguo                              Qiu Qingfeng                                           Qiu Qingfeng




                                                                                                                                         137
                                    Balance Sheet of the Parent Company
                                                   31 December 2021

Prepared by: Joincare Pharmaceutical Group Industry Co., Ltd.                              Unit: Yuan Currency: RMB
Item                                                            Note   31 December 2021            31 December 2020
Current assets:
Monetary funds                                                          1,370,906,734.13             1,469,821,002.61
Financial assets held for trading
Notes receivable                                                         374,296,302.21                53,571,233.65
Accounts receivable                                                      535,543,070.24               369,494,860.22
Receivable nancing
Prepayments                                                              201,605,530.55               319,923,532.69
Other receivables                                                       1,136,237,811.25              376,775,704.09
In which: Interest receivable
Dividends receivable                                                     814,041,000.00                69,999,500.00
Inventories                                                                                               778,363.53
Contract assets
Held-for-sale assets
Non-current assets due within one year                                                                   8,520,000.00
Other current assets                                                        9,379,100.23
Total current assets                                                    3,627,968,548.61             2,598,884,696.79
Non-current assets:
Debt investment
Other debt investment
Long-term receivables
Long-term equity investment                                             3,530,939,152.29             3,273,776,583.43
Other equity instrument investment                                       372,609,966.35               417,364,363.95
Other non-current nancial assets
Investment properties                                                       6,191,475.43                 6,191,475.43
Fixed assets                                                              45,139,232.27                45,314,938.23
Construction in progress                                                    7,890,737.14                 5,681,470.43
Productive biological assets
Oil & gas assets
Right-of-use assets                                                       12,470,703.77
Intangible assets                                                         15,316,963.24                16,497,572.49
Development expenses                                                      21,304,063.68                13,616,385.52
Goodwills
Long-term prepaid expenses                                                   900,737.50                  1,597,393.42
Deferred income tax assets                                               134,711,371.96                65,869,331.55
Other non-current assets                                                  54,866,150.94                   943,396.22
Total non-current assets                                                4,202,340,554.57             3,846,852,910.67
Total assets                                                            7,830,309,103.18             6,445,737,607.46
Current liabilities:
Short-term loans                                                         450,436,811.38               500,000,000.00
Trading nancial liabilities
Notes payable                                                            358,526,972.01
Accounts payable                                                         461,763,867.32               310,847,849.81
Receipts in advance
Contract liabilities                                                      31,637,971.91                  8,066,344.20
Payroll payable                                                           95,624,280.17                50,357,030.92
Taxes payable                                                             17,190,533.60                20,724,808.94




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Item                                                                Note                     31 December 2021              31 December 2020
Other payables                                                                                 810,207,330.35                 502,707,045.70
In which: Interests payable
Dividends payable
Held-for-sale liabilities
Non-current liabilities due within one year                                                     44,954,632.42
Other current liabilities                                                                         2,140,860.88
Total current liabilities                                                                     2,272,483,260.04              1,392,703,079.57
Non-current liabilities:
Long-term loans                                                                                160,000,000.00
Bonds payable
In which: Preferred shares
Perpetual debts
Lease liabilities                                                                                 7,683,561.03
Long-term payables
Long-term payroll payable
Estimated liabilities
Deferred income                                                                                 40,796,000.00                  43,134,800.00
Deferred income tax liabilities                                                                 29,371,338.01                  38,280,327.88
Other non-current liabilities
Total non-current liabilities                                                                  237,850,899.04                  81,415,127.88
Total liabilities                                                                             2,510,334,159.08              1,474,118,207.45
Owner's equity (or shareholder's equity):
Paid-in capital                                                                               1,907,727,908.00              1,952,780,764.00
Other equity instruments
In which: Preferred shares
Perpetual debts
Capital reserve                                                                               1,605,482,128.64              2,169,622,381.22
Less: Treasury shares                                                                          222,644,454.50                 253,637,154.50
Other comprehensive income                                                                      77,015,953.08                 110,581,751.29
Special reserve
Surplus reserve                                                                                552,219,230.70                 427,339,516.81
Undistributed prots                                                                           1,400,174,178.18                564,932,141.19
Total owner's equity (or shareholder's equity)                                                5,319,974,944.10              4,971,619,400.01
Total liabilities and owner's equity (or shareholder's equity)                                7,830,309,103.18              6,445,737,607.46

Person-in-charge of the Company:        Person-in-charge of the Company's accounting work:     Person-in-charge of the accounting department:
Zhu Baoguo                              Qiu Qingfeng                                           Qiu Qingfeng




                                                                                                                                         139
                                          Consolidated Income Statement
                                                  From January to December, 2021

Prepared by: Joincare Pharmaceutical Group Industry Co., Ltd.                                                 Unit: Yuan Currency: RMB
Item                                                                                        Note               2021                2020
I. Total revenues                                                                           V.43   15,903,688,266.59   13,521,605,768.20
In which: Operating revenues                                                                       15,903,688,266.59   13,521,605,768.20
II. Total operating costs                                                                          13,169,412,648.95   10,900,819,831.29
In which: Operating costs                                                                   V.43    5,716,293,887.58    4,874,186,898.05
Operating tax and surcharges                                                                V.44     182,816,650.02      162,642,104.11
Selling expenses                                                                            V.45    5,026,812,145.41    3,940,337,105.29
Administrative expenses                                                                     V.46     939,253,444.33      950,827,562.47
R&D expenses                                                                                V.47    1,397,131,273.33    1,071,711,981.95
Financial expenses                                                                          V.48      -92,894,751.72      -98,885,820.58
In which: Interest expenses                                                                           90,278,042.69       35,689,153.09
Interest income                                                                                      191,964,051.82      203,479,591.12
Add: Other income                                                                           V.49     247,346,934.96      248,324,865.70
Income from investments (loss is indicated by“-”)                                         V.50      71,881,264.65      182,316,456.98
In which: Income from investments in associates and joint ventures                                    10,281,021.59       17,271,121.06
Gains from derecognition of nancial assets at amortized cost
Gains from net exposure hedges (loss is indicated by“-”)
Gains from changes in fair values (loss is indicated by“-”)                               V.51      -23,506,126.09      10,217,720.09
Losses of credit impairment (loss is indicated by“-”)                                     V.52       -8,024,112.20       -6,838,947.54
Impairment loss of assets (loss is indicated by“-”)                                       V.53      -62,950,978.72      -80,786,875.70
Gains from disposal of assets (loss is indicated by“-”)                                   V.54      24,044,186.55        -1,064,564.68
III. Operating prot (loss is indicated by“-”)                                                     2,983,066,786.79    2,972,954,591.76
Add: Non-operating income                                                                   V.55        8,641,830.86      10,432,247.60
Less: Non-operating expenses                                                                V.56      39,379,273.69       33,226,763.85
IV. Total prot (loss is indicated by“-”)                                                          2,952,329,343.96    2,950,160,075.51
Less: Income tax expenses                                                                   V.57     339,480,305.29      371,693,580.17
V. Net prot (loss is indicated by“-”)                                                             2,612,849,038.67    2,578,466,495.34
(I) Classied by business continuity
1. Net prot from ongoing operation (loss is indicated by“-”)                                      2,612,849,038.67    2,578,466,495.34
2. Net prot from discontinuing operation (loss is indicated by“-”)
(II) Classied by ownership
1.Net prot attributable to shareholders of the parent company (loss is indicated by“-”)           1,328,499,432.05    1,120,439,799.25
2.Prot and loss of minority shareholders (loss is indicated by“-”)                                1,284,349,606.62    1,458,026,696.09
VI. Other comprehensive income, net of tax                                                           -177,686,201.25      76,769,040.33
(I) Other comprehensive income attributable to owners of the parent company, net of tax              -110,913,013.31         -644,580.46
1. Other comprehensive income that cannot be reclassied into prot or loss                             -78,059,481.21      37,208,220.51
(1) Changes from remeasurement of dened benet plans
(2) Other comprehensive income that cannot be reclassied into prot or loss under the
                                                                                                        6,658,847.65
equity method
(3) Changes in fair value of investments in other equity instruments                                  -84,718,328.85      37,208,220.51
(4) Changes in fair value of the enterprise's own credit risks
2. Other comprehensive income that will be reclassied into prot or loss                               -32,853,532.10      -37,852,800.97
(1) Other comprehensive income that can be reclassied into prot or loss under the
                                                                                                          -13,599.80          -18,039.87
equity method
(2) Changes in fair value of other debt investments
(3) Amount of nancial assets reclassied into other comprehensive income
(4) Provision for credit impairment of other debt investments




140
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Item                                                                                 Note                     2021                   2020
(5) Reserve for cash ow hedges
(6) Exchange dierences on translation of nancial statements denominated in foreign
                                                                                                    -32,839,932.30         -37,834,761.10
currencies
(7) Others
(II) Other comprehensive income attributable to minority shareholders, net of tax                   -66,773,187.94          77,413,620.78
VII. Total comprehensive income                                                                   2,435,162,837.42       2,655,235,535.67
(I) Total comprehensive income attributable to owners of the parent company                       1,217,586,418.74       1,119,795,218.79
(II) Total comprehensive income attributable to minority shareholders                             1,217,576,418.68       1,535,440,316.87
VIII. Earnings per share:
(I) Basic earnings per share (RMB/share)                                                                    0.6864                 0.5753
(II) Diluted earnings per share (RMB/share)                                                                 0.6858                 0.5728

Person-in-charge of the Company:       Person-in-charge of the Company's accounting work:   Person-in-charge of the accounting department:
Zhu Baoguo                             Qiu Qingfeng                                         Qiu Qingfeng




                                                                                                                                      141
                            Income Statement of the Parent Company
                                             From January to December, 2021

Prepared by: Joincare Pharmaceutical Group Industry Co., Ltd.                                              Unit: Yuan Currency: RMB
Item                                                                           Note                    2021                        2020
I. Operating revenues                                                                      2,021,173,825.62            1,433,075,511.23
Less: Operating costs                                                                      1,356,825,036.11              921,243,233.86
Operating tax and surcharges                                                                  12,392,762.31               10,221,427.14
Selling expenses                                                                             509,217,536.91              309,277,172.32
Administrative expenses                                                                      152,344,869.22              109,243,507.11
R&D expenses                                                                                  99,273,556.14               41,453,499.24
Financial expenses                                                                           -18,244,358.04              -11,350,097.41
In which: Interest expenses                                                                    4,032,165.84               10,015,894.55
Interest income                                                                               22,710,793.68               21,521,821.07
Add: Other income                                                                              1,551,111.38                2,375,942.94
Income from investments (loss is indicated by“-”)                                        1,293,747,303.58              544,379,774.53
In which: Income from investments in associates and joint ventures                            -2,005,822.14               -1,887,802.59
Gains from derecognition of nancial assets at amortized cost
Gains from net exposure hedges (loss is indicated by“-”)
Gains from changes in fair values (loss is indicated by“-”)
Losses of credit impairment (loss is indicated by“-”)                                         -203,993.20                 -948,839.02
Impairment loss of assets (loss is indicated by“-”)                                            -41,007.68                 -187,095.55
Gains from disposal of assets (loss is indicated by“-”)
II. Operating prot (loss is indicated by“-”)                                             1,204,417,837.05              598,606,551.87
Add: Non-operating income                                                                         75,665.33                1,910,488.90
Less: Non-operating expenses                                                                  13,762,938.68                8,560,790.62
III. Total prot (loss is indicated by“-”)                                                1,190,730,563.70              591,956,250.15
Less: Income tax expenses                                                                    -58,066,575.23               10,740,637.06
IV. Net prot (loss is indicated by“-”)                                                   1,248,797,138.93              581,215,613.09
(1) Net prot from ongoing operation (loss is indicated by“-”)                            1,248,797,138.93              581,215,613.09
(II) Net prot from discontinuing operation (loss is indicated by“-”)
V. Other comprehensive income, net of tax                                                     -33,565,798.21             -34,389,779.91
(I) Other comprehensive income not to be reclassied into prot and loss                        -33,565,798.21             -34,389,779.91
1. Changes from remeasurement of dened benet plans
2. Other comprehensive income that cannot be reclassied into prot or loss
under the equity method
3. Changes in fair value of investments in other equity instruments                           -33,565,798.21             -34,389,779.91
4. Changes in fair value of the enterprise's own credit risks
(II). Other comprehensive income that will be reclassied into prot and loss
1. Other comprehensive income that can be reclassied into prot or loss under
the equity method
2. Changes in fair value of other debt investments
(3) Amount of nancial assets reclassied into other comprehensive income
(4) Provision for credit impairment of other debt investments
(5) Reserve for cash ow hedges
(6) Exchange dierences on translation of nancial statements denominated in
foreign currencies
(7) Others
VI. Total comprehensive income                                                             1,215,231,340.72              546,825,833.18
VII. Earnings per share:
(1) Basic earnings per share (RMB/share)
(2) Diluted earnings per share (RMB/share)

Person-in-charge of the Company:     Person-in-charge of the Company's accounting work:   Person-in-charge of the accounting department:
Zhu Baoguo                           Qiu Qingfeng                                         Qiu Qingfeng



142
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                                                                                                                                 2021



                                      Consolidated Cash Flow Statement
                                                  From January to December, 2021

Prepared by: Joincare Pharmaceutical Group Industry Co., Ltd.                                                  Unit: Yuan Currency: RMB
Item                                                                                 Note                     2021                     2020
I. Cash ow from operating activities:
Cash received from sales of goods and rendering of services                                      16,302,075,867.93        13,571,483,724.62
Tax refunds                                                                                         142,987,224.70           133,558,486.14
Other cash received related to operating activities                                  V.58           545,037,436.64           655,216,196.75
Subtotal of cash inow from operating activities                                                  16,990,100,529.27        14,360,258,407.51
Cash paid for goods and services                                                                   4,536,979,552.07        3,560,766,056.50
Cash paid to and on behalf of employees                                                            1,950,726,146.40        1,470,505,238.58
Taxes paid                                                                                         1,653,421,224.28        1,419,695,247.36
Other cash paid related to operating activities                                      V.58          6,285,884,561.28        4,884,292,272.83
Subtotal of cash outow in operating activities                                                    14,427,011,484.03       11,335,258,815.27
Net cash ow from operating activities                                                              2,563,089,045.24        3,024,999,592.24
II. Cash ow from investing activities:
Cash received from withdrawal of investment                                                         155,208,882.44           319,220,699.26
Cash received from investment income                                                                114,833,282.84            64,666,776.09
Net cash received from disposal of xed assets, intangible assets and other long-
                                                                                                       9,404,128.73           49,081,680.14
term assets
Net cash received from disposal of subsidiaries and other business units                               3,311,220.53            5,339,063.95
Other cash received related to investing activities                                  V.58           113,574,087.21            61,508,016.38
Subtotal of cash inow from investing activities                                                     396,331,601.75           499,816,235.82
Cash paid for purchase and construction of xed assets, intangible assets and other
                                                                                                   1,521,419,292.51          830,408,355.23
long-term assets
Cash paid for investment                                                                            786,000,000.00           157,137,468.09
Net cash paid for acquisition of subsidiaries and other business units
Other cash paid related to investing activities                                      V.58            53,070,040.41            12,591,104.28
Subtotal of cash outow in investing activities                                                     2,360,489,332.92        1,000,136,927.60
Net cash ow from investing activities                                                             -1,964,157,731.17         -500,320,691.78
III. Cash ow from nancing activities:
Cash received from absorption of investments                                                        609,358,382.32           484,946,400.09
In which: Cash received by subsidiaries from investments of minority shareholders                   526,782,825.73           360,264,512.67
Borrowings received                                                                                3,534,880,943.19        2,943,579,914.03
Other cash received related to nancing activities                                    V.58            37,852,177.42             2,778,643.64
Subtotal of cash inow from nancing activities                                                      4,182,091,502.93        3,431,304,957.76
Cash repayment                                                                                     2,593,581,286.53         3,129,811,030.60
Cash paid for dividend and prot distribution or interest payment                                   1,271,374,383.55        1,035,943,628.98
In which: Dividends and prot paid by subsidiaries to minority shareholders                          888,900,577.12           675,004,435.64
Other cash paid related to nancing activities                                        V.58          1,292,040,186.29          503,763,246.33
Subtotal of cash outow in nancing activities                                                       5,156,995,856.37        4,669,517,905.91
Net cash ow from nancing activities                                                                 -974,904,353.44        -1,238,212,948.15
IV. Inuence of exchange rate uctuations on cash and cash equivalents                                 -49,290,130.94         -103,989,866.63
V. Net increase in cash and cash equivalents                                                        -425,263,170.31        1,182,476,085.68
Add: Opening balance of cash and cash equivalents                                                 12,122,781,311.49       10,940,305,225.81
VI. Closing balance of cash and cash equivalents                                                  11,697,518,141.18       12,122,781,311.49

Person-in-charge of the Company:         Person-in-charge of the Company's accounting work:   Person-in-charge of the accounting department:
Zhu Baoguo                               Qiu Qingfeng                                         Qiu Qingfeng




                                                                                                                                        143
                               Cash Flow Statement of Parent Company
                                                  From January to December, 2021

Prepared by: Joincare Pharmaceutical Group Industry Co., Ltd.                                                   Unit: Yuan Currency: RMB
Item                                                                           Note                          2021                      2020
I. Cash ow from operating activities:
Cash received from sales of goods and rendering of services                                     2,029,373,201.42           1,363,754,879.37
Tax refunds
Other cash received related to operating activities                                              606,516,829.33            1,128,399,015.69
Subtotal of cash inow from operating activities                                                 2,635,890,030.75           2,492,153,895.06
Cash paid for goods and services                                                                 983,814,721.63              822,966,958.82
Cash paid to and on behalf of employees                                                          181,261,857.67              127,975,207.89
Taxes paid                                                                                       107,046,894.42               67,292,114.59
Other cash paid related to operating activities                                                 1,062,779,580.04             909,133,528.65
Subtotal of cash outow in operating activities                                                  2,334,903,053.76           1,927,367,809.95
Net cash ow from operating activities                                                            300,986,976.99              564,786,085.11
II. Cash ow from investing activities:
Cash received from withdrawal of investment                                                       68,268,656.05               88,796,121.25
Cash received from investment income                                                             632,000,814.98              592,707,238.45
Net cash received from disposal of xed assets, intangible assets and
                                                                                                      81,400.00                4,852,059.86
other long-term assets
Net cash received from disposal of subsidiaries and other business units                                                       2,351,839.03
Other cash received related to investing activities                                              101,013,650.67
Subtotal of cash inow from investing activities                                                  801,364,521.70              688,707,258.59
Cash paid for purchase and construction of xed assets, intangible assets
                                                                                                    8,127,874.33               1,811,509.57
and other long-term assets
Cash paid for investment                                                                         319,037,191.00               78,000,000.00
Net cash paid for acquisition of subsidiaries and other business units
Other cash paid related to investing activities                                                   50,000,000.00
Subtotal of cash outow in investing activities                                                   377,165,065.33               79,811,509.57
Net cash ow from investing activities                                                            424,199,456.37              608,895,749.02
III. Cash ow from nancing activities:
Cash received from absorption of investments                                                      82,575,556.59              124,681,887.42
Borrowings received                                                                              650,000,000.00              500,000,000.00
Other cash received related to nancing activities                                                 36,583,025.57
Subtotal of cash inow from nancing activities                                                    769,158,582.16              624,681,887.42
Cash repayment                                                                                   500,000,000.00            1,300,000,000.00
Cash paid for dividend and prot distribution or interest payment                                 292,289,892.43              336,592,711.32
Other cash paid related to nancing activities                                                    701,265,930.75              253,701,833.17
Subtotal of cash outow in nancing activities                                                    1,493,555,823.18           1,890,294,544.49
Net cash ow from nancing activities                                                              -724,397,241.02           -1,265,612,657.07
IV. Inuence of exchange rate uctuations on cash and cash equivalents                                 296,539.18                    -1,416.03
V. Net increase in cash and cash equivalents                                                        1,085,731.52             -91,932,238.97
Add: Opening balance of cash and cash equivalents                                               1,369,821,002.61           1,461,753,241.58
VI. Closing balance of cash and cash equivalents                                                1,370,906,734.13           1,369,821,002.61

Person-in-charge of the Company:         Person-in-charge of the Company's accounting work:   Person-in-charge of the accounting department:
Zhu Baoguo                               Qiu Qingfeng                                         Qiu Qingfeng




144
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                                                                                                                                                                                                                                                                2021



                                     Consolidated Statement of Changes in Owner's Equity
                                                                                             From January to December, 2021

Prepared by: Joincare Pharmaceutical Group Industry Co., Ltd.                                                                                                                                                                         Unit: Yuan Currency: RMB
                                                                                                                                                                            2021
                                                                                                                                Owner's equity attributable to the parent company
                                                                                                                                                                                                                                                                Minority
Item                                                                         Other equity instruments                                                            Other                                  General                                                                 Total owner's
                                                                                                                                    Less: Treasury                         Special                                    Undistributed                         shareholder's
                                                       Paid-up capital   Preferred    Perpetual               Capital reserve                           comprehensive                Surplus reserve        risk                             Subtotal                                  equity
                                                                                                   Others                                   shares                         reserve                                           prots                                equity
                                                                            share         debts                                                                 income                                 provision
I. Balance at the end of last year                   1,952,780,764.00                                       2,533,288,674.28       253,637,154.50      116,300,559.28                515,941,465.19                6,231,451,582.26 11,096,125,890.51 8,140,772,186.49      19,236,898,077.00
Add: Change of accounting policies
Correction to errors of the previous period
Business combination involving enterprises under

common control
Others
II. Opening balance of the current year              1,952,780,764.00                                       2,533,288,674.28       253,637,154.50      116,300,559.28                515,941,465.19                6,231,451,582.26 11,096,125,890.51 8,140,772,186.49      19,236,898,077.00
III. Increase and decrease of the current year
                                                       -45,052,856.00                                       -267,931,362.36        -30,992,700.00      -110,913,013.31               124,879,713.89                 992,192,583.96     724,167,766.18    218,545,136.13       942,712,902.32
(enter“-”for decrease)
(I) Total comprehensive income                                                                                                                         -110,913,013.31                                             1,328,499,432.05   1,217,586,418.74 1,217,576,418.68      2,435,162,837.42
(II). Capital invested or decreased by owners          -45,052,856.00                                       -570,478,635.27        -30,992,700.00                                                                                     -584,538,791.27     -21,931,055.41      -606,469,846.68
1. Ordinary shares invested by the owners              10,082,440.00                                          72,493,116.59        699,900,526.87                                                                                     -617,324,970.28    437,967,405.33       -179,357,564.95
2. Capitals invested by other equity instrument
holders
3. Amount of share-based payment included in
                                                                                                               1,793,479.01                                                                                                              1,793,479.01                            1,793,479.01
owner's equity
4. Others                                              -55,135,296.00                                       -644,765,230.87 -730,893,226.87                                                                                             30,992,700.00    -459,898,460.74      -428,905,760.74
(III). Prot distribution                                                                                                                                                             124,879,713.89                -413,555,101.94    -288,675,388.05    -887,433,971.08    -1,176,109,359.13
1. Accrual of surplus reserve                                                                                                                                                        124,879,713.89                -124,879,713.89
2. Accrual of general risk provision
3. Amount distributed to owners (or shareholders)                                                                                                                                                                  -288,675,388.05    -288,675,388.05    -887,433,971.08    -1,176,109,359.13
4. Others
(IV).Internal carrying forward of owner's equity                                                                                                                                                                     77,248,253.85      77,248,253.85     94,678,535.62       171,926,789.47
1. Capital reserve transferred to increase capital
(or share capital)
2. Surplus reserve transferred to increase capital
(or share capital)
3. Surplus reserve compensating losses
4. Retained earnings carried over from changes in
the dened benet plan
5. Retained earnings carried over from other
                                                                                                                                                                                                                     77,248,253.85      77,248,253.85     94,678,535.62       171,926,789.47
comprehensive income
6. Others
(V).Special reserve
1. Accrual of the current year
2. Amount utilized in the current period
(VI). Others                                                                                                 302,547,272.91                                                                                                            302,547,272.91    -184,344,791.68      118,202,481.23
IV. Closing balance of the current period            1,907,727,908.00                                       2,265,357,311.92       222,644,454.50         5,387,545.97               640,821,179.08                7,223,644,166.22 11,820,293,656.69 8,359,317,322.63      20,179,610,979.32




                                                                                                                                                                                                                                                                                      145
                 Consolidated Statement of Changes in Owner's Equity (Cont.)
                                                                                              From January to December, 2021

Prepared by: Joincare Pharmaceutical Group Industry Co., Ltd.                                                                                                                                                                            Unit: Yuan Currency: RMB
                                                                                                                                                                           2020
                                                                                                                                Owner's equity attributable to the parent company
                                                                                                                                                                                                                                                                   Minority
Item                                                                         Other equity instruments                                                            Other                                     General                                                                Total owner's
                                                                                                                                    Less: Treasury                         Special                                       Undistributed                         shareholder's
                                                       Paid-up capital   Preferred    Perpetual               Capital reserve                           comprehensive                   Surplus reserve        risk                              Subtotal                                equity
                                                                                                   Others                                   shares                         reserve                                              prots                                equity
                                                                            share         debts                                                                 income                                    provision
I. Balance at the end of last year                   1,938,033,338.00                                       2,403,657,077.97                            116,945,139.74                  454,015,137.30                5,443,313,968.30 10,355,964,661.31 7,028,061,589.45 17,384,026,250.76
Add: Change of accounting policies
Correction to errors of the previous period
Business combination involving enterprises

under common control
Others
II. Opening balance of the current year              1,938,033,338.00                                       2,403,657,077.97                      -     116,945,139.74              -   454,015,137.30            -   5,443,313,968.30 10,355,964,661.31 7,028,061,589.45 17,384,026,250.76
III. Increase and decrease of the current year
                                                       14,747,426.00                                         129,631,596.31        253,637,154.50          -644,580.46              -    61,926,327.89            -    788,137,613.96     740,161,229.20 1,112,710,597.04      1,852,871,826.25
(enter“-”for decrease)
(I). Total comprehensive income                                                                                                                            -644,580.46                                                1,120,439,799.25   1,119,795,218.79 1,535,440,316.87     2,655,235,535.67
(II). Capital invested or decreased by owners          14,747,426.00                                         125,566,742.45        253,637,154.50                     -             -                 -           -                  -    -113,322,986.05    98,645,829.86       -14,677,156.19
1. Ordinary shares invested by the owners              14,747,426.00                                         109,934,461.42        253,637,154.50                                                                                         -128,955,267.08    77,986,526.50       -50,968,740.58
2. Capitals invested by other equity instrument
                                                                                                                                                                                                                                                        -                                     -
holders
3. Amount of share-based payment included in
                                                                                                              15,632,281.03                                                                                                                15,632,281.03     20,659,303.36       36,291,584.39
owner's equity
4. Others                                                                                                                                                                                                                                               -                                     -
(III). Prot distribution                                             -                                                                                                                   58,121,561.31            -   -366,545,084.51     -308,423,523.20   -593,243,501.42    -901,667,024.62
1. Accrual of surplus reserve                                                                                                                                                            58,121,561.31                  -58,121,561.31                  -                                     -
2. Accrual of general risk provision                                                                                                                                                                                                                    -                                     -
3. Amount distributed to owners (or
                                                                                                                                                                                                                      -308,423,523.20     -308,423,523.20   -593,243,501.42    -901,667,024.62
shareholders)
4. Others                                                                                                                                                                                                                                               -                                     -
(IV) . Internal carrying forward of owner's
                                                                                                                                                                                          3,804,766.58            -     34,242,899.22      38,047,665.80                   -     38,047,665.80
equity
1. Capital reserve transferred to increase capital
                                                                                                                                                                                                                                                        -                                     -
(or share capital)
2. Surplus reserve transferred to increase capital
(or share capital)
3. Surplus reserve compensating losses
4. Retained earnings carried over from changes
in the dened benet plan
5. Retained earnings carried over from other
                                                                                                                                                                                          3,804,766.58                  34,242,899.22      38,047,665.80                         38,047,665.80
comprehensive income
6. Others
(V) . Special reserve
1. Accrual of the current year
2. Amount utilized in the current period
(VI) . Others                                                                                                  4,064,853.86                                                                                                                  4,064,853.86    71,867,951.73       75,932,805.59
IV. Closing balance of the current period            1,952,780,764.00                                       2,533,288,674.28       253,637,154.50       116,300,559.28              -   515,941,465.19            -   6,231,451,582.26 11,096,125,890.51 8,140,772,186.49 19,236,898,077.00


Person-in-charge of the Company:                                              Person-in-charge of the Company's accounting work:                                                                     Person-in-charge of the accounting department:
Zhu Baoguo                                                                    Qiu Qingfeng                                                                                                           Qiu Qingfeng




146
                                                                                                                                                                                                      Annual Report
                                                                                                                                                                                                              2021



            Statement of Changes in Owner's Equity of the Parent Company
                                                                                From January to December, 2021

Prepared by: Joincare Pharmaceutical Group Industry Co., Ltd.                                                                                                                         Unit: Yuan Currency: RMB
                                                                                                                                            2021
                                                                                  Other equity instruments                                                  Other
Item                                                                                                                               Less: Treasury                    Special                        Undistributed      Total owner's
                                                               Paid-up capital Preferred Perpetual               Capital reserve                    comprehensive              Surplus reserve
                                                                                                      Others                               shares                    reserve                               prots              equity
                                                                                  share       debts                                                        income
I. Balance at the end of last year                           1,952,780,764.00                                  2,169,622,381.22    253,637,154.50   110,581,751.29             427,339,516.81     564,932,141.19    4,971,619,400.01
Add: Change of accounting policies
Correction to errors of the previous period
Others
II. Opening balance of the current year                      1,952,780,764.00                                  2,169,622,381.22    253,637,154.50   110,581,751.29             427,339,516.81     564,932,141.19    4,971,619,400.01
III. Increase and decrease of the current year (enter“-”
                                                               -45,052,856.00                                  -564,140,252.58     -30,992,700.00   -33,565,798.21             124,879,713.89     835,242,036.99     348,355,544.09
for decrease)
(I). Total comprehensive income                                                                                                                     -33,565,798.21                               1,248,797,138.93   1,215,231,340.72
(II). Capital invested or decreased by owners                  -45,052,856.00                                  -570,478,635.27     -30,992,700.00                                                                   -584,538,791.27
1. Ordinary shares invested by the owners                      10,082,440.00                                     72,493,116.59     699,900,526.87                                                                   -617,324,970.28
2. Capitals invested by other equity instrument holders
3. Amount of share-based payment included in owner's
                                                                                                                   1,793,479.01                                                                                         1,793,479.01
equity
4. Others                                                      -55,135,296.00                                  -644,765,230.87 -730,893,226.87                                                                        30,992,700.00
(III). Prot distribution                                                                                                                                                       124,879,713.89    -413,555,101.94    -288,675,388.05
1. Accrual of surplus reserve                                                                                                                                                  124,879,713.89    -124,879,713.89
2. Amount distributed to owners (or shareholders)                                                                                                                                                -288,675,388.05    -288,675,388.05
3. Others
(IV). Internal carrying forward of owner's equity
1. Capital reserve transferred to increase capital (or
share capital)
2. Surplus reserve transferred to increase capital (or
share capital)
3. Surplus reserve compensating losses
4. Retained earnings carried over from changes in the
dened benet plan
5. Retained earnings carried over from other
comprehensive income
6. Others
(V). Special reserve
1. Accrual of the current year
2. Amount utilized in the current period
(VI). Others                                                                                                       6,338,382.69                                                                                      6,338,382.69
IV. Closing balance of the current period                    1,907,727,908.00                                  1,605,482,128.64    222,644,454.50    77,015,953.08             552,219,230.70    1,400,174,178.18   5,319,974,944.10




                                                                                                                                                                                                                              147
 Statement of Changes in Owner's Equity of the Parent Company (Cont.)
                                                                             From January to December, 2021

Prepared by: Joincare Pharmaceutical Group Industry Co., Ltd.                                                                                                                         Unit: Yuan Currency: RMB
                                                                                                                                            2020
                                                                                 Other equity instruments                                                   Other
tem                                                                                                                                Less: Treasury                    Special                       Undistributed      Total owner's
                                                              Paid-up capital Preferred Perpetual                Capital reserve                    comprehensive              Surplus reserve
                                                                                                      Others                               shares                    reserve                              prots              equity
                                                                                 share       debts                                                         income
I. Balance at the end of last year                        1,938,033,338.00                                     2,045,946,209.82                     144,971,531.20             365,413,188.92    316,018,713.39    4,810,382,981.33
Add: Change of accounting policies                                                                                                                                                                                                -
Correction to errors of the previous period                                                                                                                                                                                       -
Others                                                                                                                                                                                                                            -
II. Opening balance of the current year                   1,938,033,338.00                                     2,045,946,209.82                 -   144,971,531.20             365,413,188.92    316,018,713.39    4,810,382,981.33
III. Increase and decrease of the current year
                                                          14,747,426.00                                         123,676,171.40     253,637,154.50   -34,389,779.91              61,926,327.89    248,913,427.80     161,236,418.68
(enter“-”for decrease)
(I). Total comprehensive income                                                                                                                     -34,389,779.91                               581,215,613.09     546,825,833.18
(II). Capital invested or decreased by owners             14,747,426.00                                         114,786,996.27     253,637,154.50                -                           -                 -   -124,102,732.23
1. Ordinary shares invested by the owners                 14,747,426.00                                         109,934,461.42     253,637,154.50                                                                  -128,955,267.08
2. Capitals invested by other equity instrument holders                                                                                                                                                                           -
3. Amount of share-based payment included in owner's
                                                                                                                   4,852,534.85                                                                                        4,852,534.85
equity
4. Others                                                                                                                                                                                                                         -
(III). Prot distribution                                  -                                                                    -                -                -              58,121,561.31    -366,545,084.51   -308,423,523.20
1. Accrual of surplus reserve                                                                                                                                                   58,121,561.31     -58,121,561.31                  -
2. Amount distributed to owners (or shareholders)                                                                                                                                                -308,423,523.20   -308,423,523.20
3. Others                                                                                                                                                                                                                         -
(IV) . Internal carrying forward of owner's equity        -                                                                    -                -                -               3,804,766.58     34,242,899.22      38,047,665.80
1. Capital reserve transferred to increase capital
                                                                                                                                                                                                                                  -
(or share capital)
2. Surplus reserve transferred to increase capital
                                                                                                                                                                                                                                  -
(or share capital)
3. Surplus reserve compensating losses                                                                                                                                                                                            -
4. Retained earnings carried over from changes
                                                                                                                                                                                                                                  -
in the dened benet plan
5. Retained earnings carried over from other
                                                                                                                                                                                 3,804,766.58     34,242,899.22      38,047,665.80
comprehensive income
6. Others                                                                                                                                                                                                                         -
(V) Special reserve                                       -                                                                    -                -                -                           -                 -                  -
1. Accrual of the current year                                                                                                                                                                                                    -
2. Amount utilized in the current period                                                                                                                                                                                          -
(VI) Others                                                                                                        8,889,175.13                                                                                        8,889,175.13
IV. Closing balance of the current period                 1,952,780,764.00                                     2,169,622,381.22    253,637,154.50   110,581,751.29             427,339,516.81    564,932,141.19    4,971,619,400.01

Person-in-charge of the Company:                                Person-in-charge of the Company's accounting work:                                      Person-in-charge of the accounting department:
Zhu Baoguo                                                      Qiu Qingfeng                                                                            Qiu Qingfeng




148
                                                                                                                  Annual Report
                                                                                                                          2021



                Joincare Pharmaceutical Group Industry Co., Ltd
                        Notes to the financial statements
                          (All amounts in RMB Yuan unless otherwise stated)

I. Company Profile

1. Overview
   √ Applicable □ N/A

   Shenzhen Aimier Food Co., Ltd., the predecessor of the Company, was a Sino-foreign joint venture ocially established on 18
   December 1992 with the approval from Shenzhen Administration for Industry and Commerce. It was primarily engaged in the
   production and sale of Taitai oral liquid.

   On 19 January 1994, the Company changed its name to“Shenzhen Taitai Health Food Co., Ltd. * ( 深圳太太保健食品有限公司 )”
   On 4 July 1995, the Company changed its name to“Shenzhen Taitai Pharmaceutical Co., Ltd. * ( 深圳太太药业有限公司 )”.

    The Company was wholly reorganized into a company limited by shares with 31 August 1999 as the base date of joint-stock
    system reorganization pursuant to the resolution of the General Meeting and upon approval by Shenzhen Municipal People's
    Government Document [1999] No. 197 on 16 September 1999 and 10 November 1999. The Company convened the Founding
    Meeting on 12 November 1999, completed the changes of the industrial and commercial registration on 24 November 1999,
    renewed the business license with registration number of Qi He Yue Shen Zong Zi No. 103358A, and changed its name to
  “Shenzhen Taitai Pharmaceutical Co., Ltd. *( 深 圳 太 太 药 业 股 份 有 限 公 司 )”. The Company set 1 September 1999 as the
    eective date of the joint-stock system reorganization in accounting.

   On 6 February 2001, the Company was approved by CSRC to issue domestic shares (A shares) to the public according to the
   Notice on the Approval of Public Offering by Shenzhen Taitai Pharmaceutical Co., Ltd. (Zheng Jian Fa Xing Zi [2001] No.
   21). On 8 June 2001, shares of the Company were listed and traded on Shanghai Stock Exchange.

   On 25 May 2001, the Company went through the registration formalities for industrial and commercial changes and renewed
   the business license with registration number of 4403011066279.

   Pursuant to the resolution approved at the General Meeting on 21 May 2002, the Company issued 5 shares for every 10 shares
   by way of conversion of capital reserve based on the share capital of the Company on 31 December 2001. The Company
   renewed the business license with the registration number unchanged.

   On 4 June 2003, the Company changed its name to Shenzhen Health Pharmaceutical Industry Group Co., Ltd.* ( 深 圳 健 康 药
   业 集 团 股 份 有 限 公 司 ). On 29 September 2003, the Company changed its name to Joincare Pharmaceutical Group Industry
   Co., Ltd. * ( 健康元药业集团股份有限公司 ).

   Pursuant to the resolution approved at the General Meeting on 29 September 2003, the Company issued 5 shares for every
   10 shares by way of conversion of capital reserve based on the share capital of the Company on 30 June 2003. The Company
   renewed the business license with the registration number unchanged.

   On 2 December 2005, the Company was changed to a company limited by shares with foreign investment (with proportion of
   foreign investment lower than 25%) and renewed the business license with the registration number changed to Qi He Yue Shen
   Zong Zi No. 111262 upon approval by the Ministry of Commerce of the People's Republic of China.

   The Reform Scheme for Non-tradable Shares of the Company was approved at the General Meeting on 16 October 2006
   and implemented on 23 November 2006. According to the Scheme, shareholders of tradable shares may obtain 3.80 shares
   of share consideration implemented by shareholders of non-tradable shares for every 10 tradable shares they held. After
   the implementation of the Reform Scheme for Non-tradable Shares, the number of shares held by shareholders and the
   shareholding ratio of shareholders of the Company were changed, but the total share capital, assets, liabilities, owner's equities,
   net prots and other nancial indicators of the Company were not changed.



                                                                                                                                 149
      Pursuant to the resolution approved at the General Meeting on 26 March 2008, the Company issued 8 shares for every 10
      shares to all shareholders and distributed cash dividends of RMB1 (tax inclusive) based on 609,930,000 shares, the total
      share capital of the Company at the end of 2007. The Company renewed the business license with the registration number
      unchanged.

      Pursuant to the resolution approved at the General Meeting on 31 March 2010, the Company issued 2 shares for every 10
      shares by way of conversion of capital reserve based on the share capital of the Company on 31 December 2009. The Company
      renewed the business license with the registration number unchanged.

      Pursuant to the resolution approved at the General Meeting on 15 February 2011, it was agreed that the Company repurchased
      certain public shares by way of centralized price bidding in the trading system of Shanghai Stock Exchange provided that
      the total amount of funds for repurchase was no more than RMB300 million and the share repurchase price was no more
      than RMB12.00/share, and canceled such shares in accordance with law, with a repurchase period of 12 months from the
      date when the resolution was approved. As at 30 November 2011, the Company repurchased 29,252,223 shares, accounting
      for approximately 2.220% of the total issued share capital. The maximum repurchase price was RMB11.33/share and the
      minimum repurchase price was RMB7.07/share. The total amount paid was RMB299,999,708.87 (including stamp duty and
      commission), reaching the cap of RMB300 million. The Company completed the Scheme for Repurchasing Certain Public
      Shares and went through the formalities for cancellation of repurchased shares with the Shanghai Branch of China Securities
      Depository and Clearing Corporation Limited. The post-repurchase share capital was 1,288,196,577 shares.

      Pursuant to the resolution approved at the General Meeting on 20 April 2012, the Company issued 2 shares for every 10
      shares by way of conversion of capital reserve based on the Company's share capital of 1,288,196,577 shares. The share
      capital after the conversion was 1,545,835,892 shares. The Company renewed the business license with registration number of
      440301501126176.

      In May 2015, the Company implemented the Equity Incentive Scheme and issued 38,043,400 restricted shares to 214 equity
      incentive participants. The registered capital was changed to 1,583,879,292 shares. The Company completed the changes of
      securities registration with the Shanghai Branch of China Securities Depository and Clearing Corporation Limited in July
      2015. Moreover, the Company completed the changes of the industrial and commercial registration on 23 February 2016, with
      unied social credit code of 91440300618874367T.

      On 21 December 2015, the Company granted the first batch of reserved restricted shares in the Equity Incentive Scheme in
      May 2015 to 39 equity incentive participants, and the actual number of exercised options was 3,150,000. The Company's total
      share capital following the exercise changed to 1,587,029,292 shares. In February 2016, the Company completed the changes
      of securities registration with the Shanghai Branch of China Securities Depository and Clearing Corporation Limited.

      On 16 May 2016, the Company granted the second batch of reserved restricted shares in the Equity Incentive Scheme in May
      2015 to 38 equity incentive participants, and the actual number of exercised options was 1,360,000. The Company's total share
      capital following the exercise changed to 1,588,389,292 shares. On 25 July 2016, the Company completed the changes of
      securities registration with the Shanghai Branch of China Securities Depository and Clearing Corporation Limited.

      Pursuant to“the Resolution on Repurchase and Cancellation of Restricted Shares Granted But Not Yet Unlocked Held by
      Some Incentive Participants”considered and approved at the 20th Meeting of the 6th Session of the Board on 18 August 2016,
      1,250,000 shares were repurchased. After the repurchase, the Company's total share capital changed to 1,587,139,292 shares.
      On 18 November 2016, the Company completed the changes of securities registration with the Shanghai Branch of China
      Securities Depository and Clearing Corporation Limited.

      Pursuant to the“Resolution on Repurchase and Cancellation of Restricted Shares Granted But Not Yet Unlocked Held by
      Some Incentive Participants”considered and approved at the 27th Meeting of the 6th Session of the Board on 23 November
      2016, 1,238,000 shares were repurchased. After the repurchase, the Company's total share capital changed to 1,585,901,292
      shares. On 25 January 2017, the Company completed the changes of securities registration with the Shanghai Branch of China
      Securities Depository and Clearing Corporation Limited.




150
                                                                                                          Annual Report
                                                                                                                  2021


Pursuant to the“Resolution on Repurchase and Cancellation of Restricted Shares Granted But Not Yet Unlocked Held by
Some Incentive Participants”considered and approved at the 33rd Meeting of the 6th Session of the Board on 27 April 2017,
12,123,020 shares were repurchased. After the repurchase, the Company's total share capital changed to 1,573,778,272 shares.
On 19 July 2017, the Company completed the changes of securities registration with the Shanghai Branch of China Securities
Depository and Clearing Corporation Limited.

Pursuant to the“Resolution on Repurchase and Cancellation of Restricted Shares Granted But Not Yet Unlocked Held by
Some Incentive Participants”considered and approved at the 46th Meeting of the 6th Session of the Board on 21 March 2018,
850,000 shares were repurchased. After the repurchase, the Company's total share capital changed to 1,572,928,272 shares.
On 19 June 2018, the Company completed the changes of securities registration with the Shanghai Branch of China Securities
Depository and Clearing Corporation Limited.

On 18 October 2018, pursuant to the resolutions of the 34th Meeting of the 6th Session of the Board on 11 May 2017, the 2016
Annual General Meeting on 8 June 2017, the 41st Meeting of the 6th Session of the Board on 16 November 2017, the 48th
Meeting of the 6th Session of the Board on 26 April 2018, and the 2017 Annual General Meeting on 22 May 2018, as approved
by China Securities Regulatory Commission ( 中 国 证 券 监 督 管 理 委 员 会 ) with“Approval in Relation to the Allotment of
Shares by Joincare Pharmaceutical Group Industry Co., Ltd. * ( 健康元药业集团股份有限公司 )”(Zheng Jian Xu Ke [2018]
No. 1284) on 17 August 2018, 365,105,066 ordinary shares denominated in Renminbi (A Shares) of the Company were
issued to the original shareholders through allotment of shares with a nominal value of RMB1.00 each. After the issuance,
the Company's total share capital changed to 1,938,033,338 shares. This capital increase was validated and confirmed by the
Capital Verication Report (Ruihua Yan Zi [2018] No. 40060006) issued by Ruihua Certied Public Accountants.

Pursuant to“the Resolution on 2018 Share Options Incentive Scheme (Draft) and its Summary”considered and approved at
the 2018 Third Extraordinary General Meeting on 13 December 2018 and the“Resolution in Relation to the Adjustment of
the Quantity to be Granted and the List of Incentive Participants of the Grant under 2018 Share Options Incentive Scheme”
considered and approved at the 7th Meeting of the 7th Session of the Board on 24 January 2019, 21 December 2018 was set
as the date of grant, on which 35.72 million share options were granted to 320 incentive participants at an exercise price of
RMB8.21 per share option. Pursuant to“the Resolution on the Grant of Share Options to Incentive Participants under the
Reserved Grant”considered and approved at the 16th Meeting of the 7th Session of the Board on 23 September 2019 and“the
Resolution in Relation to the Adjustment of the Quantity for the Reserved Grant and the List of Incentive Participants of the
Reserved Grant under 2018 Share Options Incentive Scheme”considered and approved at the 17th Meeting of the 7th Session
of th e Board on 28 October 2019, 23 September 2019 was set as the date of grant, on which 8.97 million reserved share
options were granted to 186 incentive participants at an exercise price of RMB10.47 per share option.

8,887,186 share options were exercised from January to March 2020, which was validated and confirmed by the Capital
Verification Report (Zhi Tong Yan Zi [2020] No. 442ZC0063) issued by Grant Thornton; 617,109share options were exercised
from April to June 2020, which was validated and confirmed by the Capital Verification Report (Zhi Tong Yan Zi [2020] No.
442ZC00200) issued by Grant Thornton; 3,249,839 share options were exercised from July to September 2020, which was
validated and conrmed by the Capital Verication Report (Zhi Tong Yan Zi [2020] No. 442ZC00368) issued by Grant Thornton;
and 1,993,292 share options were exercised from October to December 2020, which was validated and conrmed by the Capital
Verification Report (Zhi Tong Yan Zi [2021] No. 442C000002) issued by Grant Thornton. As at 31 December 2020, a total of
14,747,426 share options were exercised; and the Company's total share capital was increased to 1,952,780,764 shares.

3,848,413 share options were exercised from January to March 2021, which was validated and confirmed by the Capital
Verification Report (Zhi Tong Yan Zi [2021] No. 442C000151) issued by Grant Thornton (Special General Partnership);
and 1,964,040 share options were exercised from April to June 2021, which was validated and confirmed by the Capital
Verification Report (Zhi Tong Yan Zi [2021] No. 442C000453) issued by Grant Thornton (Special General Partnership).
1,899,922 share options were exercised from July to September 2021, which was validated and confirmed by the Capital
Verification Report (Zhi Tong Yan Zi [2021] No. 442C000667) issued by Grant Thornton; and 2,370,065 share options were
exercised from October to December 2021, which was validated and confirmed by the Capital Verification Report (Zhi Tong
Yan Zi [2022] No. 442C000008) issued by Grant Thornton.




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      Pursuant to the Resolution on Share Repurchase Scheme by Way of Centralized Price Bidding and other resolutions
      considered and approved at the 41st Meeting of the 7th Session of the Board and the 2021 First Extraordinary General
      Meeting of the Company on 9 February 2021 and 25 February 2021, respectively, it was approved that the Company
      repurchased company shares shall be cancalled and thus to reduce registered capital of the Company.The Company completed
      the cancellation of repurchased 55,135,296 shares with the Shanghai Branch of China Securities Depository and Clearing
      Corporation Limited on 16 September 2021.

      As of 31 December2021, the total share capital of the Company was 1,907,727,908 shares after exercising options and
      cancelling of the repurchased shares during 2021.

      The controlling shareholder of the Company is Shenzhen Baiyeyuan Investment Co., Ltd. * ( 深圳市百业源投资有限公司 ),
      and the de facto controller is Zhu Baoguo.

      The Company is engaged in the integrated pharmaceutical industry.

      The nature of business and principal activities of the Company and its subsidiaries: primarily engaged in the R&D, production
      and sale of pharmaceutical products and healthcare products, which covered drug preparation products, active pharmaceutical
      ingredients (“APIs”) and intermediates, diagnostic reagents and equipment as well as healthcare products.

      During the Reporting Period, there was no change in the principal activities of the Company.

      The financial statements and notes to the financial statements of the Company were approved at the 9th Meeting of the 8th
      Session of the Board on 29 August 2022.

 2. Scope of consolidated financial statements
      √ Applicable □ N/A

      Please refer to Note VII“Equity in other entities”for names of subsidiaries included in the consolidation in 2021. Please refer
      to Note VI“Change to consolidation scope”for details of change to current consolidation scope of the Company.


II. Basis of Preparation for the Financial Statements

 1. Basis of preparation
      The Company's nancial statements have been prepared on the going-concern basis.


 2. Continuing operation
      √ Applicable □ N/A

      The nancial statements have been prepared in accordance with the Accounting Standards for Business Enterprises issued by
      the MOF and its application guidance, interpretations and the other related provisions (collectively, the“Accounting Standards
      for Business Enterprises”). In addition, the Company also discloses relevant financial information in accordance with the
      Information Disclosure and Presentation Rules for Companies Oering Securities to the Public No. 15 – General Provisions on
      Financial Reporting (2014 Revision) issued by the CSRC.

      The nancial statements have been prepared on the going-concern basis.

      The Company's accounting is measured on an accrual basis. Except for certain nancial instruments, these nancial statements
      are generally measured at historical cost. Non-current assets held for sale are stated at the lower of fair value less estimated
      selling costs and their original carrying amount if they qualify as held for sale. In case of asset impairment, the Company shall
      make provisions for impairment in accordance with applicable provisions.


III. Significant Accounting Policies and Accounting Estimates

      Specic accounting policies and accounting estimate tips:
      √ Applicable □ N/A


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    The Company determines the depreciation of fixed assets, amortisation of intangible assets, capitalisation condition of R&D
    expenses and revenue recognition policies on the basis of its production and operation characteristics. Details of accounting
    policies are set out in Note III.16, Note III.20, Note III.21 and Note III.28.


1. Statement of compliance with the Accounting Standards for Business Enterprises
    The nancial statements comply with the Accounting Standards for Business Enterprises, which gave a true and complete view
    of the consolidated and the Company's financial position as at 31 December 2021, and the consolidated and the Company's
    operating results and the consolidated and the Company's cash ow and other relevant information for 2021.


2. Accounting period
    The scal year of the Company is from 1 January to 31 December in each calendar year.


3. Business cycle
    √ Applicable □ N/A

    Business cycle of the Company consists of 12 months.


4. Functional currency
    The functional currency of the Company and its domestic subsidiaries is Renminbi (“RMB”). Overseas subsidiaries of the
    Company usually recognise HK dollar, Macau dollar and US dollar as their functional currencies according to the primary
    economic environment of which these subsidiaries operate. The Company prepares its nancial statements in RMB.


5. Accounting treatment for business combinations involving enterprises under common control and business
   combinations involving enterprises not under common control
    √ Applicable □ N/A

(1) Business combinations involving enterprises under common control

    For the business combination involving entities under common control, the assets acquired and liabilities assumed are
    measured based on their carrying amounts in the consolidated financial statements of the ultimate controlling party as at
    the combination date, except the adjustment made due to different accounting policies. The difference between the carrying
    amount of the consideration paid for the combination and the net assets acquired is adjusted against share premium in the
    capital reserve, with any excess adjusted against retained earnings.

    Business combination involving enterprises under common control and achieved in a number of transactions

    In the separate financial statements, the initial investment cost will be recognised at the carrying amount of the Company's
    share in the combined party's net assets in the consolidated nancial statements of the ultimate controlling party on the date of
    combination. The dierence between the initial investment cost and the sum of the carrying amount of the investment held and
    the carrying amount of consideration paid for the combination at the combination date is adjusted against share premium in the
    capital reserve, with any excess adjusted against retained earnings.

    In the consolidated financial statements, the assets acquired and liabilities assumed are measured based on their carrying
    amounts in the consolidated financial statements of the ultimate controlling party as at the combination date, except the
    adjustment made due to different accounting policies. The difference between sum of the carrying amount of the investment
    held and the carrying amount of the consideration paid for the combination and the carrying amount of the net assets acquired
    is adjusted against share premium in the capital reserve, with any excess adjusted against retained earnings. For long-term
    equity investment held before the control over the combined party is obtained, profit or loss, other comprehensive income
    and other changes to equity interest attributable to the owners recognised from the later of the acquisition of the original
    equity interest and the date when the combing party and the combined party are placed under common control until the date
    of combination shall be offset against retained profit at the beginning of the period of the comparative financial statements or
    prot or loss of the period respectively.


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 (2) Business combinations involving enterprises not under common control

      For the business combinations involving enterprises not under common control, the combination cost shall be the fair value
      of the assets transferred, liabilities incurred or assumed, and equity securities issued by the acquirer for acquisition of control
      in the acquiree on the acquisition date. The assets, liabilities and contingent liabilities acquired or assumed on the date of
      acquisition are recognised at fair value.

      Where the combination cost exceeds the fair value of the acquiree's identifiable net assets in the business combination, the
      dierence is recognised as goodwill and is subsequently measured at cost less accumulated impairment provisions. Where the
      combination cost is less than the fair value of the acquiree's identiable net assets in the business combination, the dierence
      shall be included in prot or loss for the period after review.

      Business combination involving enterprises not under common control and achieved in a number of transactions.

      In the separate financial statements, the initial cost of the investment is the sum of the carrying amount of the acquiree's
      equity investment held before the acquisition date and the additional investment cost on the acquisition date. In respect of the
      equity investment held prior to the acquisition date, other comprehensive income will not be recognised using equity method
      on the acquisition date, and such investment will be accounted for on the same accounting treatment as direct disposal of
      relevant asset or liability by the investee at the time of disposal. Shareholder's equity recognised due to the changes of other
      shareholder's equity other than the changes of net loss and profit, other comprehensive income and profit distribution shall
      be transferred to profit or loss for current period when disposed. If the equity investment held prior to the acquisition date is
      measured at fair value, the cumulative changes in fair value recognised in other comprehensive income shall be transferred to
      prot or loss for current period when accounted for using cost method.

      In the consolidated financial statements, the combination cost is the sum of consideration paid on the acquisition date and
      fair value of the acquiree's equity held prior to the acquisition date. The equity of the acquirees held before the acquisition
      date is re-measured at the fair value of the equity on the acquisition date and the differences between the fair value and the
      carrying amount are recognised in the income for the current period; in respect of any other comprehensive income attributable
      to the equity interest in the acquiree held prior to the acquisition date and any changes of other shareholder's equity shall be
      transferred to investment profit or loss for current period on the acquisition date, except for the other comprehensive income
      incurred due to the changes arising from remeasuring net assets or net liabilities of defined benefit plan attributable to the
      acquiree.

 (3) Transaction fees attribution during the combination

      The intermediary and other relevant administrative expenses such as audit, legal and valuation advisory for business
      combinations are recognised in profit or loss when incurred. Transaction costs of equity or debt securities issued as the
      considerations of business combination are included in the initial recognition amounts.


 6. Preparation of consolidated financial statements
      √ Applicable □ N/A

 (1) Scope of consolidation

      The scope of consolidated financial statements is determined based on control. Control means the Company has exposures
      or rights to variable returns from its involvement with the investee and the ability to affect those returns through power over
      such investee. Subsidiaries are the entities controlled by the Company(including enterprises, a dividable part of investees and
      structured entities).




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(2) Method for preparation of the consolidated nancial statements

    The consolidated financial statements are based on the financial statements of the Company and its subsidiaries, and are
    prepared by the Company in accordance with other relevant information. In preparing the consolidation financial statements,
    the Company and its subsidiaries are required to apply consistent accounting policy and accounting period, intra-group
    transactions and balances shall be oset.

    A subsidiary or a business acquired through a business combination involving entities under common control in the reporting
    period shall be included in the scope of the consolidation of the Company from the date when it is under control of the ultimate
    controlling party, and then its operating results and cash flows will be included in the consolidated income statement and the
    consolidated cash ow statement, respectively.

    For a subsidiary or a business acquired through a business combination involving entities not under common control in the
    reporting period, its income, expenses and profits are included in the consolidated income statement, and its cash flows are
    included in the consolidated cash ow statement from the acquisition date to the end of the reporting date.

    The shareholders' equity of the subsidiaries that are not attributable to the Company shall be presented under shareholders'
    equity in the consolidated balance sheet as minority interests. The portion of net profit or loss of subsidiaries for the period
    attributable to minority interest is presented in the consolidated income statement under the“profit or loss of minority
    interest”. When the amount of loss attributable to the minority shareholders of a subsidiary exceeds the minority shareholders'
    portion of the opening balance of owners' equity of the subsidiary, the excess amount shall be allocated against minority
    interest.

(3) Purchase of the minority stake in the subsidiary

    The difference between the long-term equity investments costs acquired by the purchase of minority interests and the share
    of the net assets that the subsidiaries have to continue to calculate from the date of purchase or the date of consolidation in
    proportion to the new shareholding ratio, and the difference between the disposal of the equity investment without losing
    control over its subsidiary and the disposal of the long-term equity investment corresponding to the share of the net assets
    of the subsidiaries from the date of purchase or the date of consolidation, shall be adjusted to the capital reserve (or share
    premium), if the capital reserve is not sucient, any excess will be adjusted to retained earnings.

(4) Treatment of loss of control of subsidiaries

    Where the Company loses its control over the original subsidiary due to the disposal of some equity investment or other
    reasons, the remaining equity is re-measured at its fair value on the date when the Company loses its control. The difference
    between the sum of the consideration acquired due to the disposal of the equity and the fair value of the remaining equity, and
    the Company's share in the sum of carrying value of net assets of the original subsidiary and goodwill calcu lated on an on-
    going basis from the acquisition date based on the original shareholding proportion is recognised in the investment income for
    the current period when the control is lost.

    Other comprehensive income in relation to the original subsidiary's equity investment are transferred to profit or loss for the
    current period when control ceases, except for those arising from re-measuring net assets or net liabilities of defined benefit
    plan by the investee.

(5) Treatment of disposal through several transactions until the loss of control of subsidiaries

    Where the Company disposes of the equity interests in the subsidiary through several transactions until it loses control, and
    the transaction terms, conditions and economic effects satisfy one or several of the following circumstances, such several
    transactions shall be deemed as a basket of transactions in accounting treatment:

    ①   Such transactions are entered into simultaneously or upon the consideration of the mutual impacts;
    ②   No complete commercial result will be realised without such transactions as a whole;
    ③   The occurrence of one transaction depends on the occurrence of at least another transaction;
    ④   The result of an individual transaction is not economical, but it would be economical after taken into account of other
         transactions in the series.


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      In the separate financial statements, where the Company disposes of the equity investment in the subsidiary through several
      transactions until the loss of control, and such transactions are not regarded as“a basket of transactions”, the carrying amount
      of the long-term equity investment involving each disposal will be carried forward, with the difference between the disposal
      price and the carrying amount of the long-term equity investment involving the disposal being accounted into the investment
      incomes for the current period; where the transactions constitute“a basket of transactions”, the difference between the
      consideration of each disposal and the carrying amount of the long-term equity investment involving the disposal before the
      loss of the control, is recognised as the other comprehensive income and will be carried forward to the profit or loss for the
      current period when the control is lost.

      In the consolidated financial statements, where the Company disposes of the equity investment in the subsidiary through
      several transactions until the loss of control, the measurement of the remaining equity interest and the accounting treatment
       of the losses and gains of the disposal will be made with reference to the“Treatment of loss of control of subsidiaries”as
      described above. For the difference between the consideration of each disposal before the loss of the control and the carrying
      amount of the Company's share in the net assets involving the disposal of such subsidiary calculated on an on-going basis from
      the acquisition date, the treatment will be made as follows:

      ① In case the transactions are“a basket of transactions”, such difference is recognised as the other comprehensive income
         and will be carried forward to the prot or loss for the current period when the control is lost.
      ② In case the transactions are not“a basket of transactions”, such difference is accounted into the capital reserve (or share
         premium) as equity, and shall not be carried forward to the prot or loss for the current period when the control is lost.


 7. Classification of joint arrangement and accounting treatment for joint operation
      √ Applicable □ N/A

      A joint arrangement is an arrangement jointly controlled by two or more parties. The Company's joint arrangement is classied
      into the joint operation and the joint venture.

 (1) Joint operation
     A joint operation is a joint arrangement whereby the Company have rights and obligations to the relevant assets and liabilities.
     The Company recognises the following items in relation to its interest in a joint operation, and makes corresponding
     accounting treatment in accordance with relevant accounting standards:

      A. The solely-held assets, and the share of any assets held jointly;
      B. The solely-assumed liabilities, and its share of any liabilities incurred jointly;
      C. Its revenue from the sale of its share of the output arising from the joint operation;
      D. Its share of the revenue from the sale of the output by the joint operation;
      E. The solely-incurred expenses, including its share of any expenses incurred jointly.

 (2) Joint ventures
     A joint venture is a joint arrangement whereby the Company only entitled to the net assets of the arrangements.
     The Company's investment in joint ventures is accounted for using the equity method according to the rules of the long-term
     equity investment.


 8. Standards for determination of cash and cash equivalents
      Cash and cash equivalents of the Company include cash on hand, bank deposit readily available for payment and those
      investments held by the Company that are short-term (normally due in three months since the acquisition date), highly liquid,
      readily convertible into known amounts of cash and subject to an insignicant risk of change in value.


 9. Foreign currency transactions and translation of financial statements in foreign currency
      √ Applicable □ N/A




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(1) Foreign currency transactions

    Foreign currency transactions incurred by the Company are translated to the functional currency at the spot exchange rates on
    the date of the transactions upon initial recognition.

    Monetary items denominated in foreign currencies are translated to functional currency at the spot exchange rate on the
    balance sheet date. Exchange dierences arising from the dierences between the spot exchange rate prevailing at the balance
    sheet date and those spot rates used on initial recognition or at the previous balance sheet date are recognised in prot or loss
    for the current period; non-monetary items denominated in foreign currencies that are measured at historical cost are translated
    using the spot exchange rate on the transaction date. Non-monetary items denominated in foreign currencies that are measured
    at fair value are translated using the spot exchange rate on the date the fair value is determined; the resulting exchange
    dierences between the amounts in functional currency upon translation and in original functional currency are recognised in
    prot or loss for the current period.

(2) Translation of nancial statements in foreign currency

   At the balance sheet date, when translating the foreign currency financial statements of overseas subsidiaries, the assets
   and liabilities in the balance sheet are translated at the spot exchange rate at the balance sheet date; all items except for
   “undistributed prots”of the shareholders' equity are translated at the spot exchange rate on the transaction date.

    The revenue and expenses in prot or loss are translated at the spot exchange rate on the transaction date.

    All items in the statement of cash ows are translated at the spot exchange rate on the transaction date. The eect of exchange
    difference on cash is adjusted and separately presented as“Effect of changes in foreign exchange rates on cash and cash
    equivalents”in the cash ow statement.

    The exchange differences arising from translation of the financial statements are presented as the“other comprehensive
    income”in the shareholders' equity of the balance sheet.

    When the Company disposes of the overseas operation and loses control, the differences arising from the translation of the
    financial statements in foreign currency that have been presented under the shareholders' equity in the balance sheet and
    involving such overseas operation are carried forward to the profit or loss for the current period in whole or in the proportion
    of the disposal of the overseas operation.


10. Financial instruments
    √ Applicable □ N/A

    Financial instruments are contracts creating financial assets of a party and financial liabilities or equity instruments of other
    parties.

(1) Recognition and De-recognition of nancial instruments

    A nancial asset or nancial liability is recognised when the Company becomes one of the parties under a nancial instrument
    contract.
    The nancial assets will be de-recognised if any of the following conditions is satised:
    ① The contractual right to receive the cash ow of the nancial assets is terminated;
    ② The financial assets have been transferred and the transferred financial asset satisfies the following conditions of de-
    recognition.

    If the current obligation of a nancial liability (or a part thereof) has been discharged, the nancial liability (or that part of the
    financial liability) will be derecognised. When the Company (as the debtor) and the lender have signed an agreement which
    uses a new financial liability to replace the existing financial liability, and the contract terms of the new financial liability are
    substantially different with the original financial liability, the original financial liability shall be de-recognised, and the new
    nancial liability shall be recognised at the same time.

    The regular transactions of the nancial assets are recognised and derecognised at the transaction date.



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 (2) Classication and measurement of nancial assets

      The Company classifies financial assets into three categories: financial assets at amortised cost; financial assets at fair value
      through other comprehensive income; and financial assets at fair value through profit or loss based on the business model for
      managing nancial assets and their contractual cash ow characteristics upon initial recognition.

      Financial assets at amortised cost

      The Company shall classify nancial assets that meet the following conditions and are not designated as nancial assets at fair
      value through prot or loss for the current period as nancial assets measured at amortised cost:

      A. The Company's business model for managing the nancial assets is to collect contractual cash ow;
      B. The terms of the financial asset contract stipulate that the cash flow generated on a specific date is only the payment for
      principal and interest accrued on the outstanding principal.

      After initial recognition, these financial assets are measured at amortised cost using the effective interest method. Gains
      or losses arising from financial assets which are measured at amortised cost and not part of any hedging relationship are
      included in the profit and loss of the current period upon de-recognition, amortisation using the effective interest method, or
      impairments recognition.

      Financial assets at fair value through other comprehensive income

      The Company shall classify financial assets that meet the following conditions and are not designated as financial assets
      measured at fair value through profit or loss for the current period as financial assets measured at fair value through other
      comprehensive income:
      A. The Company's business model for managing the financial assets is both to collect contractual cash flows and to sell the
      nancial assets;
      B. The terms of the financial asset contract stipulate that the cash flow generated on a specific date is only the payment for
      principal and interest accrued on the outstanding principal.

      After initial recognition, these nancial assets are subsequently measured at fair value. Interest, impairment losses or gains and
      exchange losses and gains calculated using the eective interest method are recognised in prot or loss for the current period,
      while other gains or losses are recognised in other comprehensive income. The cumulative prot or loss previously included in
      other comprehensive income will be transferred to the prot or loss for the current period upon derecognition of the nancial
      assets.

      Financial assets at fair value through prot or loss for the current period

      In addition to the above financial assets which are measured at amortised cost or at fair value a through other comprehensive
      income, the Company classifies all other financial assets as financial assets measured at fair value through profit or loss for
      the current period. When initial recognition, in order to eliminate or signicantly reduce accounting mismatches, the Company
      irrevocably designates some financial assets that should have been measured at amortised cost or at fair value through other
      comprehensive income as nancial assets at fair value through prot or loss for the current period.

      After initial recognition, these financial assets are subsequently measured at fair value, and the profits or losses (including
      interest and dividend income) generated from which are recognised in prot or loss for the current period, unless the nancial
      assets are part of the hedging relationship.

      However, with respect to non-trading equity instrument investments, the Company may irrevocably designate them as nancial
      assets measured at fair value through other comprehensive income at initial recognition. The designation is made on the basis
      of individual investment, and the relevant investment conforms to the denition of equity instruments from the issuer's point of
      view.

      After initial confirmation, financial assets are subsequently measured at fair value. Dividend income that meets the
      requirements is recognised in profit and loss, and other gains or losses and changes in fair value are recognised in other
      comprehensive gains. When derecognised, the accumulated gains or losses previously recognised in other comprehensive gains
      are transferred from other comprehensive gains to retained earnings.


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    The business model of managing financial assets refers to how the Company manages financial assets to generate cash flow.
    The business model decides whether the source of cash ow of nancial assets managed by the Company is to collect contract
    cash ow, sell nancial assets or both of them. Based on objective facts and the specic business objectives of nancial assets
    management decided by key managers, the Company determines the business model of nancial assets management.

    The Company evaluates the characteristics of the contract cash ow of nancial assets to determine whether the contract cash
    flow generated by the relevant financial assets on a specific date is only to pay principal and interest based on the amount of
    unpaid principal. Among them, principal refers to the fair value of financial assets at the time of initial confirmation; interest
    includes the consideration of time value of money, credit risk related to the amount of unpaid principal in a specic period, and
    other basic borrowing risks, costs and prots. In addition, the Company evaluates the terms and conditions of the contracts that
    may lead to changes in the time distribution or amount of cash ow in nancial asset contracts to determine whether they meet
    the requirements of the above contract cash ow's characteristics.

    Only when the Company changes its business model of managing financial assets, all the financial assets affected shall be
    reclassified on the first day of the first reporting period after the business model changes, otherwise, financial assets shall not
    be reclassied after initial conrmation.

    Financial assets are measured at fair value on initial recognition. The relevant transaction cost of nancial assets at fair value
    through profit or loss is directly recognised in profit or loss for the current period, and that of other types of financial assets
    is included in the initially recognised amount. Trade receivables or notes receivable arising from sales of goods or rendering
    services, without significant financing component, are initially recognised based on the transaction price expected to be
    entitled by the Company.

(3) Classication and measurement of nancial liabilities

    On initial recognition, the Company's financial liabilities are classified into financial liabilities at fair value through profit or
    loss and nancial liabilities at amortised cost. For nancial liabilities not classied as nancial liabilities at fair value through
    prot or loss, the relevant transaction costs are included in the initially recognised amount.

    Financial liabilities at fair value through prot or loss

    Financial liabilities at fair value through profit or loss include financial liabilities held for trading and financial liabilities
    designated at fair value through profit or loss upon initial recognition. Such financial liabilities are subsequently measured at
    fair value, all gains and losses arising from changes in fair value and dividend and interest expense relative to the financial
    liabilities are recognised in prot or loss for the current period.

    Financial liabilities at amortised cost

    Other financial liabilities are subsequently measured at amortised cost using the effective interest method; gains and losses
    arising from derecognition or amortisation is recognised in prot or loss for the current period.

    Distinction between nancial liabilities and equity instruments

    The nancial liability is the liability that meets one of following criteria:
    ① Contractual obligation to deliver cash or other nancial instruments to another entity.
    ② Under potential adverse condition, contractual obligation to exchange financial assets or financial liabilities with other
       parties.
    ③ A contract that will or may be settled in the entity's own equity instruments and is a non-derivative for which the entity is
       or may be obliged to deliver a variable number of the entity's own equity instruments.
    ④ A derivative that will or may be settled other than by the exchange of a xed amount of cash or another nancial asset for a
       xed number of the entity's own equity instruments.

    An equity instrument is any contract that evidences a residual interest in the assets of an entity after deducting all of its
    liabilities.

    If the Company cannot unconditionally avoid fullling a contractual obligation by delivering cash or other nancial assets, the
    contractual obligation meets the denition of nancial liability.


                                                                                                                                    159
      If a nancial instrument must or are able to be settled by the Company's own equity instrument, the Company should consider
      whether the Company's equity instrument as the settlement instrument is a substitute of cash or other financial assets or the
      residual interest in the assets of the Company after deducting all of its liabilities. If the former, the tool is the Company's
      nancial liability; if the latter, the tool is the equity instrument of the Company.

 (4) Derivative nancial instruments and embedded derivatives

      The Company's derivative nancial instruments include forward foreign exchange contracts, and are initially measured at fair
      value on the date of the derivative contract signed and are subsequently measured at fair value. A derivative with positive fair
      value shall be recognised as an asset, otherwise that with negative fair value shall be recognised as a liability. Any prot or loss
      arising from changes of fair value and not compliance with the accounting provision of hedge shall be recognised as prot or
      loss for current period.

      For the hybrid instrument which includes embedded derivatives, where the host contract is a financial asset, requirements in
      relation to the classification of financial assets shall apply to the hybrid instrument as a whole. Where the host contract is not
      a nancial asset, and the hybrid instrument is not measured at fair value and its changes are included in the prot and loss for
      the current period for accounting purposes, there is no close relation between the embedded derivatives and the host contract in
      terms of economic features and risks, and the instrument that has the same condition with the embedded derivatives and exists
      independently meets the definition of derivatives, the embedded derivatives shall be separated from the hybrid instrument
      and treated as a separate derivative financial instrument. If it is unable to separately measure the embedded derivatives upon
      acquisition or on the subsequent balance sheet date, the hybrid instrument shall be entirely designated as the nancial assets or
      nancial liabilities measured at fair value and whose movements are included in the prot and loss of the current period.

(5) Fair value of the nancial instrument

      The methods for determining the fair value of the nancial assets or nancial liabilities are set out in Note III.11.

(6) Impairment of nancial assets

      The following items are subject to impairment accounting and recognition of loss allowances based on expected credit losses:
      A. Financial assets measured at amortised cost;
      B. Receivables and debt investments that are measured at fair value through other comprehensive income;
      C. Contract assets as dened in the Accounting Standard for Business Enterprises No. 14 – Revenue;
      D. Lease receivables;
      E. Financial guarantee contracts, except for those carried at fair value through profit or loss, those which the transfer of
      financial assets does not satisfy the derecognition condition or those formed as a result of continued involvement of the
      transferred nancial assets.

      Measurement of expected credit loss (ECLs)

      The ECL is a weighted average of credit losses on financial instruments weighted at the risk of default. Credit loss is the
      dierence between all receivable contractual cash ows according to the contract and all cash ows expected to be received by
      the Company discounted to present value at the original eective interest rate, i.e. the present value of all cash shortfalls.

      The Company takes into account reasonable and valid information on past events, current conditions and forecasts of future
      economic conditions, with the risk of default as the weight, to calculate the probabilistic weighted amount of the present value
      of the difference between the cash flow receivable from contract and the expected cash flow to be received and recognise the
      expected credit loss.

      The Company respectively measures the expected credit losses of financial instruments by different stages. If the credit
      risk of the financial instrument does not increase significantly since the initial recognition, it would be classified in Stage 1,
      the Company would measure loss allowance according to the future 12-month expected credit losses. If the credit risk of a
      financial instrument has significantly increased since the initial recognition but not yet credit-impaired, it would be classified
      in Stage 2, the Company would measure loss allowance according to the lifetime expected credit losses of that instrument. If
      the financial instrument has credit-impaired since the initial recognition, it would be classified in Stage 3, and the Company
      would measure loss allowance according to the lifetime expected credit losses of that instrument.


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For financial instruments with lower credit risk on the balance sheet date, the Company assumes that its credit risk has not
increased significantly since the initial recognition, and measures loss allowance according to the 12-month expected credit
losses.

Lifetime ECLs are the ECLs that result from all possible default event over the expected life of a nancial instrument. Future
12-month ECLs are the portion of ECL that results from default events on a nancial instrument that are possible within the 12
months after the balance sheet date (or the expected life of the instrument, if it is less than 12 months).

The maximum period considered when estimating ECLs is the maximum contractual period over which the Company are
exposed to credit risk (including the option to renew).

For the financial instruments classified in Stage 1 and Stage 2 and those with lower credit risk, the Company would measure
the interest income by the book balance (that is, without deduction for credit allowance) and the effective interest rate. For
nancial instruments classied in Stage 3, the Company would measure the interest income by the amortised cost (that is, book
balance less impairment allowance) and the eective interest rate.

For notes receivable, trade receivables and contract assets, regardless whether it has significant financing components or not,
the Company has always measured its loss allowance at an amount equal to lifetime expected credit losses.

If the expected credit losses of one individual nancial asset cannot be estimated at a reasonable cost, the Company classies
notes receivable and trade receivables into portfolios based on credit risk characteristics, and measures expected credit losses
on portfolios basis to determine portfolios by the following basis:

A. Bills receivable
 Bills receivable portfolio 1: Bank acceptance bills
 Bills receivable portfolio 2: Commercial acceptance bills

B. Accounts receivables
 Accounts receivables portfolio 1: Amount due from domestic customers
 Accounts receivables portfolio 2: Amount due from overseas customers
 Accounts receivables portfolio 3: Receivables of consolidated companies

Contract assets

Contract assets portfolio: Sale of products

For bills receivable classied as portfolio, the Company measures expected credit losses based on the risk exposures of default
and lifetime expected credit losses rate with reference to the historical credit loss experience, current situation and forecasts of
future economic conditions.

For accounts receivables classified as portfolio, the Company measures expected credit losses through preparing a table of
concordance between the aging of trade receivables and lifetime expected credit losses rate with reference to the historical
credit loss experience, current situation and forecasts of future economic conditions.

Other receivables

The Company classifies other receivables into certain portfolios based on credit risk characteristics, and measures expected
credit losses on portfolios basis to determine portfolios by the following basis:
 Other receivables portfolio 1: Receivables of export tax refund
 Other receivables portfolio 2: Receivables of deposits under guarantee and security deposits and lease expenses
 Other receivables portfolio 3: Other receivables
 Other receivables portfolio 4: Receivables of consolidated companies

For other receivables classified as portfolio, the Company measures expected credit losses based on the risk exposures of
default and future 12-month or lifetime expected credit losses rate.

Long-term receivables




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      The Company's long-term receivables include nance lease receivables and equity transfer receivables.

      The Company classifies finance lease receivables and equity transfer receivables into certain portfolios based on credit risk
      characteristics, and measures expected credit losses on portfolios basis to determine portfolios by the following basis:

      A. Finance lease receivables
       Portfolio of nance lease receivables: other receivables

      B. Other long-term receivables
       Portfolio of other long-term receivables: equity transfer receivables

      For finance lease receivables and equity transfer receivables, the Company measures expected credit losses based on the risk
      exposures of default and lifetime expected credit losses rate with reference to the historical credit loss experience, current
      situation and forecasts of future economic conditions.

      For other receivables and long-term receivables other than finance lease receivables and equity transfer receivables that
      are classified as portfolio, the Company measures expected credit losses based on the risk exposures of default and future
      12-month or lifetime expected credit losses rate.

      Debt investments and other debt investments

      For debt investments and other debt investments, the Company measures expected credit losses based on the nature of
      investments, counterparties and various types of risk exposures and the risk exposures of default and future 12-month or
      lifetime expected credit losses rate.

      Assessment of signicant increase in credit risk

      By comparing the risk of default of financial instruments occurring on the balance sheet date and on the initial recognition
      date, the Company determines the relative changes in risk of default over the expected life of financial instruments and
      assesses whether the credit risk of nancial instruments have increased signicantly since the initial recognition.

      When determine whether credit risks have significantly increased since the initial recognition, the Company considers
      information that is reasonable and supportable, including forward-looking information that is available without undue cost or
      eort. The information considered by the Company includes:
       Failure to make payments of principal or interest on debtors' contractually due dates;
       An actual or expected signicant deterioration in a nancial instrument's external or internal credit rating (if any);
        An actual or expected signicant deterioration in the operating results of debtors;
       Existing or forecast changes in the technological, market, economic or legal environment that have a significant adverse
      eect on the debtors' abilities to repay to the Company.

      Depending on the nature of the financial instruments, the Company assesses whether credit risks have significantly increased
      on either an individual nancial instrument basis or a collective nancial instrument basis. When the assessment is performed
      on a collective financial instrument basis, the Company can classify the financial instruments based on the shared credit risk
      characteristics, such as past due information and credit risk ratings.

      The Company determines that the credit risk on a nancial instrument has increased signicantly if it is more than 30 days past
      due.

      Credit-impaired nancial assets

      The Company assesses whether financial assets at amortised cost and debt investments measured at fair value through other
      comprehensive income are credit-impaired at balance sheet date. A nancial asset is‘credit-impaired' when one or more events
      that have an adverse impact on the estimated future cash flows of the financial asset have occurred. Evidence that a financial
      asset is credit-impaired includes the following observable information:
       Signicant nancial diculty of the issuer or debtor;
       A breach of contract by debtor, such as a default or delinquency in interest or principal payments;
       For economic or contractual reasons relating to the borrower's financial difficulty, the Company having granted to the



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    borrower a concession that would not otherwise consider;
     It is probable that the borrower will enter bankruptcy or other nancial reorganization;
     The disappearance of an active market for that nancial asset because of nancial diculties.

    Presentation of allowance for ECL

    The Company re-measures the ECLs on each balance sheet date to reect changes in the nancial instruments' credit risk since
    initial recognition, and the increase or reversal of the loss provision resulted therefrom is recognised as an impairment gain or
    loss in prot or loss. For nancial assets measured at amortised cost, the loss provision is oset against their carrying amounts
    in the balance sheet. For debt investments at FVOCI, the Company recognises the loss provision in other comprehensive
    income and does not deduct the carrying amount of the nancial assets.

    Write-o

    The gross carrying amount of a financial asset is written off (either partially or in full) to the extent that there is no realistic
    prospect of recovery. A write-o constitutes a derecognition event. This is generally the case the Company determines that the
    debtor does not have assets or sources of income that could generate sufficient cash flows to repay the amounts subject to the
    write-o. However, nancial assets that are written o could still be subject to enforcement activities in order to comply with
    the Company's procedures for recovery of amounts due.

    Subsequent recoveries of an asset that was previously written o are recognised as a reversal of impairment in prot or loss in
    the period in which the recovery occurs.

(7) Transfer of nancial assets

    Transfer of nancial assets refers to the transfer or delivery of nancial assets to the other party (the transferee) other than the
    issuer of nancial assets.

    The Company derecognises a financial asset only if it transfers substantially all the risks and rewards of ownership of the
    nancial asset to the transferee; the Company should not derecognise a nancial asset if it retains substantially all the risks and
    rewards of ownership of the nancial asset.

    The Company neither transfers nor retains substantially all the risks and rewards of ownership, shows as the following
    circumstances: if the Company has forgone control over the financial assets, derecognise the financial assets and verify the
    assets and liabilities; if the Company retains its control of the financial asset, the financial asset is recognised to the extent of
    its continuing involvement in the transferred nancial asset and recognise an associated liability is recognised.

(8) Osetting nancial assets and nancial liabilities

    When the Company has the legal right to offset recognised financial assets and financial liabilities, and the legal right can be
    executed at present, and the Company has a plan to settle the nancial assets and nancial liabilities at the same time or at net
    amount, the nancial assets and nancial liabilities can be presented on the balance sheet after osetting. Except for the above
    circumstances, nancial assets and nancial liabilities cannot be oset and shall be presented separately on the balance sheet.


11. Fair value measurement
    The fair value is defined as the price that would be received to sell an asset or paid to transfer a liability in an orderly
    transaction between market participants at the measurement date.

    The Company measures the relevant assets or liability at fair value supposing the orderly transaction of asset selling or liability
    transferring incurring in a principal market of relevant assets or liabilities. In the absence of a principal market for the asset or
    liability, the Company assumes that the transaction takes place at the most advantageous market of relevant asset or liability. A
    principal market (or the most advantageous market) is the transaction market that the Company can enter into at measurement
    date. The Company implements the hypothesis used by the market participants to realise the maximum economic benefit in
    assets or liabilities pricing.




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      If there exists an active market for the financial assets or financial liabilities, the Company uses the quotation on the active
      market as its fair value. For those in the absence of active market, the Company uses valuation technique to recognise its
      fair value. However, under limited circumstances, the Company may use all information about the results and operation of
      the investee obtained after the date of initial recognition to determine whether cost represents fair value. Cost may represent
      the best estimate of fair value of the relevant financial asset within the scope of distribution, and such cost represents the
      appropriate estimate of fair value within the scope of distribution.

      For non-nancial assets measured at fair value, the Company should consider the capacity of the market participants to put the
      assets into optimal use thus generating the economic benet, or the capacity to sell assets to other market participants who can
      put the assets into optimal use and generate economic benet.

      The Company implements the valuation technique suitable for the current condition and supported by enough available data
      and other information, gives priority in use of relevant observable inputs, only the observable inputs cannot be obtained or
      impracticable before using unobservable inputs.

      For the assets and liabilities measured or disclosed at fair value on nancial statements, fair value hierarchies are categorized
      into three levels as the lowest level input that is significant to the entire fair value measurement: Level 1: inputs are
      quoted prices (unadjusted) in active markets for identical assets and liabilities. Level 2: inputs are inputs other than quoted
      prices included within Level 1 that are observable for the asset or liability, either directly or indirectly. Level 3: inputs are
      unobservable inputs for the asset or liability.

      At each balance sheet date, the Company re-evaluates the assets and liabilities recognised to be measured at fair value on the
      nancial statements to make sure whether conversion occurs between fair value hierarchies.


12. Inventories
      √ Applicable □ N/A

 (1) Classication of inventories

      The Company's inventories include raw materials, packaging materials, finished goods, work-in-progress, low-value
      consumables, subcontracting materials, inventory goods and expendable biological assets.

 (2) Method of costing

      The method of costing of the Company's inventories: Cost of finished goods are measured at planned cost, and material cost
      differences are carried forward at the end of the period to adjust planned cost to actual cost; other inventories are measured
      at actual cost on acquisition and raw materials received are accounted for by the weighted-average method; low-value
      consumables and packaging materials are amortised in full upon the use.

 (3) The underlying factors in the determination and the basis of provision for diminution in net realisable value of inventories

      On the balance sheet date, the inventories are calculated at the lower of cost and the net realisable value. When the net
      realisable value is lower than the cost, the provision for diminution in value of inventories is made on an item-by-item basis
      at the excess of the cost of the inventory over its net realisable value. For large volume inventories with low unit price,
      the provision for diminution in the value of inventories is made by categories. Inventories that are related to a product line
      manufactured and sold in the same region, have the same or similar end use or purpose, and are dicult to measure separately
      from other items are consolidated the provision for diminution in the value of inventories.

 (4) Inventory system

      The Company maintains a perpetual inventory system.

 (5) Amortisation methods of consumables

      Low-value consumables of the Company are amortised in full when used.




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13. Assets held for sale
    √ Applicable □ N/A

(1) Category and measurement of non-current assets or the disposal group held for sale

    Non-current assets and disposal groups are classied as held for sale if the Company recovers its book value mainly by selling
    (including the exchange of nonmonetary assets with commercial substance) rather than continuing to use it.

    The aforesaid non-current assets do not include investment property measured with the basis of fair value; the biological assets
    measured with the basis of fair value less selling costs; the assets formed by employee benefits; financial assets and the right
    arising from deferred income tax assets and insurance contracts.

    A disposal group is a group of assets to be disposed through sale or other means as a whole in a single transaction, and
    liabilities directly associated with those assets that will be transferred in the transaction. In certain circumstance, disposal
    groups include the goodwill obtained through business combination.

    Non-current assets and disposal groups that meet the following conditions are classified as held for sale: according to the
    practice of disposing of this type of assets or disposal groups in a similar transaction, a non-current asset or disposal group is
    available for immediate sale at its present condition; the sale is likely to occur, that is, a decision has been made on a sale plan
    and a determined purchase commitment is made, and the sale is expected to be completed within one year. Where the loss
    of control over the subsidiaries is due to the sales of investment in subsidiaries, no matter whether the Company retains part
    of the equity investment after selling or not, the investment in subsidiaries shall be classified as held for sale in the separate
    financial statements when it satisfies the conditions for category of held for sale; all assets and liabilities of subsidiaries shall
    be classied as held for sale in the consolidated nancial statements.

    The dierence between carrying amount of non-current assets or disposal groups classied as held for sale and the net amount
    of fair value less selling costs shall be recognised as impairment loss on assets upon initial measurement or when such non-
    current assets or disposal groups are remeasured at the balance sheet date. For the amount of impairment loss on assets
    recognised in disposal groups, the carrying amount of disposal groups' goodwill shall be offset against first, and then offset
    against the carrying amount of non-current assets according to the proportion of carrying amount of the individual non-current
    assets in the disposal groups.

    If on a subsequent balance sheet date, the net amount of the fair value of a held-for-sale disposal group less its selling costs
    increases, the amount reduced previously shall be recovered, and reversed in the asset impairment loss recognised on the non-
    current asset which is applicable to the measurement requirements of Held-For-Sale Standards after the non-current asset is
    classied into held-for-sale category. The reversed amount is credited to current prot or loss. The carrying value of goodwill
    which has been oset cannot be reversed.

    No depreciation or amortisation is provided for the non-current assets in the held-for-sale and the assets in the disposal group
    held for sale. The interest on the liabilities and other costs in the disposal group held for sale is recognised continuously. As
    far as all or part of investment in the associates and joint ventures is concerned, for the part classified into the held-for-sale
    category, the accounting with equity method shall be stopped, while the remaining part (which is not classified into the held-
    for-sale category) shall still be accounted for using the equity method. When the Company loses the significant influence on
    the associates and joint venture due to the sale, the use of equity method shall be stopped.

    When certain non-current asset or disposal group classified into the held-for-sale category no longer meets the classification
    criteria for held-for-sale category, the Company shall stop classifying it into the held-for-sale category and measure it
    according to the lower of the following two amounts:
    ① The carrying amount of the asset of disposal group before it was classified into the held-for-sale category after being
        adjusted with the depreciation, amortisation or impairment that could have been be recognised if it was not classied into
        the held-for-sale category;
    ② The recoverable amount.




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 (2) Discontinued operation

      Discontinued operation refers to the component meeting one of the following conditions that has been disposed of by the
      Company or classied by the Company into the held-for-sale type and can be identied separately:
      ① The component represents an independent principal business or a separate principal business place.
      ② The component is a part of the related plan for the contemplated disposal of an independent principal business or a separate
         principal business place.
      ③ The component is a subsidiary acquired exclusively for the purpose of resale.

 (3) Presentation

      The Company presents the non-current assets held for sale and the assets in the disposal group held for sale under“assets
      classied as held for sale”, and the liabilities in the disposal group held for sale under“liabilities classied as held for sale”in
      the balance sheet.

      The Company presents the prot and loss for continuing operation and prot and loss for discontinued operation in the income
      statement, respectively. The impairment loss and reversal amount and disposal profit and loss of the non-current assets held
      for sale or disposal group not meeting the definition of discontinued operation will be presented as the profit and loss of
      continuing operation. The operating prot and loss (such as impairment loss and reversal amount) and disposal prot and loss
      of the discontinued operation will be presented as the prot and loss of the discontinued operation.

      The disposal group proposed for retirement rather than sale and meeting the condition about the relevant component in the
      denition of the discontinued operation will be presented as discontinued operation from the date of retirement.

      For the discontinued operation reported in the current period, the information formerly presented as profit and loss of
      continuing operation will be presented as the prot and loss of discontinued operation for the comparable accounting period in
      the financial statement of the current period. If the discontinued operation no longer meets the classification criteria for held-
      for-sale category, the information formerly presented as prot and loss of discontinued operation will be presented as the prot
      and loss of continuing operation for the comparable accounting period in the nancial statement of the current period.


14. Long-term equity investment
      √ Applicable □ N/A

      The long-term equity investment includes the equity investment in the subsidiary, joint ventures and associates. The investee
      over which the Company has signicant inuence is the associates of the Company.

(1) Determination of initial investment cost

      The long-term equity investment resulting from corporate merger: For the long-term equity investment resulting from merger
      of companies under the same control, the carrying amount of the ownership equity of the merged party obtained on the merger
      date presented in the consolidated nancial statement of the nal controlling party will be used as the investment cost. For the
      long-term equity investment resulting from merger of companies under different controls, the merger cost will be used as the
      investment cost of the long-term equity investment.

      The long-term equity investment obtained by other means: For the long-term equity investment obtained by paying cash, the
      actually paid purchase price will be used as the initial investment cost. For the long term equity investment obtained by issuing
      equity securities, the fair value of the issued equity securities will be used as the initial investment cost.

 (2) Subsequent measurement and recognition method of prot or loss

      The investment in subsidiary will be accounted for using cost method, unless the investment meets the criteria of held-for-sale
      category. The investment in associates and joint venture will be accounted with equity method.

      For the long-term equity investment accounted for using cost method, except for the price actually paid upon the investment or
      the cash dividend or prot in the consideration that has been declared but not released, the cash dividend or prot declared and
      distributed by the investee is recognised as the investment income and recorded into the prot and loss for the current period.



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For the long-term equity investment accounted for using equity method, the investment cost of the long-term equity investment
shall not be adjusted if the initial investment cost of the long-term equity investment is higher than the Company's share in the
fair value of the identifiable net value of the investee at the time of investment; if the initial investment cost of the long-term
equity investment is lower than the Company's share in the fair value of the identifiable net value of the investee at the time
of investment, the carrying amount of the long-term equity investment will be adjusted, with the difference recorded into the
prot and loss for the current period of investment.

When accounted for using the equity method, return on investment and other comprehensive income are recognised according
to the share in the investee's realised net prot or loss and other comprehensive income respectively, and the carrying amount
of the long-term equity investment is adjusted. The carrying amount of the long-term equity investment will be deducted
according to the prot distribution declared by the investee or cash dividend attributable to the Company. The carrying amount
of long term equity investment will be adjusted for changes to equity interest attributable to the owners of the investee other
than net profit or loss, other comprehensive income and profit distribution, and recorded into capital reserve (other capital
reserve). The Company's share of the net profit or loss of the investees will be recognised after adjustment of the net profit
of the investees according t o the accounting policy and accounting period of the Company on the basis of fair value of all
identiable assets of the investee on acquisition.

If the Company is able to exert significant influence or implement joint control (which does not constitute control) on the
investee through additional investment or other reason, the sum of the fair value of the original equity plus the additional
investment cost will be used as the initial investment cost, which will be accounted for with equity method, on the conversion
date. The difference between the fair value of the original equity on the conversion date and its carrying amount, and the
accumulated change of fair value recorded into other comprehensive income will be transferred into the prot and loss for the
current period, which will be accounted for using equity method.

If an entity loses joint control or has no significant influence over investees due to the elimination of parts of the equity
investment, the surplus equity after disposal shall be recognised in accordance with“Accounting Standards for Business
Enterprises No. 22 – Recognition and Measurement of Financial Instruments”, and the difference between fair value and
carrying amount should be recognised as profit or loss for current period. Other comprehensive income of original equity
investment recognised under equity method shall be recognised in accordance with the same foundation used by the investees
when dispose the relevant assets or liabilities directly in the termination of equity method. Other changes of owners' equity
related to the original equity investment shall be transferred into prot or loss for current period.

If an entity loses control over investees due to the elimination of parts of the equity investment, the surplus owners' equity
that is able to implement joint control or have significant influence over investees shall be measured at equity method and
are deemed to be recognised under equity method since the acquisition date. The surplus owners' equity that are unable to
implement joint control or have no significant influence over investees shall be processed in accordance with“Accounting
Standards for Business Enterprises No. 22 – Recognition and Measurement of Financial Instruments”, and the difference
between fair value and carrying amount at the day of loss of control shall be recognised as prot or loss for current period.

If the shareholding ratio of the Company is reduced due to the increase of capital of other investors, and thus the control is
lost, but the joint control or signicant inuence can be exerted on the invested entity, the Company should recognise net asset
according to the new shareholding ratio. The difference between the original book value of the long-term equity investment
corresponding to the decrease in the shareholding ratio should be included in the current prot and loss; then, according to the
new shareholding ratio, the equity method is used to adjust the investment.

The Company recognises the unrealised prot or loss of intra-transaction between the joint ventures or associates that belongs
to itself according to the proportion of the shares and recognises the investment income or loss after oset. However, the loss
arising from the unrealised intra-transaction between the Company and investees, which belongs to the impairment loss of
assets transferred, cannot be oset.




                                                                                                                              167
 (3) Basis of determining common control and signicant inuence on the investee

      Joint control is the contractually agreed sharing of control over an arrangement under which the decisions relating to any
      activity require the unanimous consent of the parties sharing control. In determining whether there is a joint control, the first
      judge is to determine whether the relevant arrangement is controlled collectively by all the parties involved or the group of the
      parties involved. Secondly, and then determine whether the decisions related to the basic operating activities should require the
      unanimous consent of the parties involved. If the parties involved or the group of the parties involved must act consistently to
      determine the relevant arrangement, it is considered that the parties involved or the group of the parties involved control the
      arrangement. If two or more parties involve in the collectively control of certain arrangement, it shall not be considered as joint
      control. Protection of rights shall not be considered in determining whether there is joint control.

      Significant influence refers to the power to participate in the decision making process for financial and operational policies
      of the investees without control or common control over the formulation of such policies. When determining whether it has
      significant influence over the investee, the influence of the voting shares of the investee held by the investor directly and
      indirectly and the potential voting rights held by the investor and other parties which are exercisable in the current period
      and converted to the equity of the investee, including the warrants, stock options and convertible bonds that are issued by the
      investee and can be converted in the current period, shall be taken into account.

      When the Company owns directly or indirectly through its subsidiaries more than 20% (including 20%) but less than 50% of
      the voting shares of the investee, it is generally considered to have signicant inuence over the investee, unless there is clear
      evidence that it cannot participate in the production and operation decisions of the investee and does not have a significant
      inuence under such circumstances. When the Company owns less than 20% (excluding) of the voting shares of the investee, it
      is generally not considered to have signicant inuence on the investee unless there is clear evidence that it can participate in
      the production and operation decisions of the investee and have signicant inuence under such circumstances.

 (4) Held-for-sale equity investment

      Refer to note III. 13 for the relevant accounting treatment of the equity investment to joint ventures or associates all or partially
      classied as assets held for sale.

      The surplus equity investments that are not classied as assets held for sale shall be accounted for using equity method.

      The equity investment to joint ventures or associates already classied as held for sale no longer meets the conditions of assets
      held for sale shall be adjusted retroactively using equity method from the date of being classied as assets held for sale.

 (5) Impairment test and Impairment provision

      Refer to note III. 22 for investment to subsidiaries, associates and joint ventures and the impairment provision of assets.


15. Investment properties
      Investment properties are properties held to earn rental or capital appreciation or both. The investment properties of the
      Company include land use rights that have already been leased out, land use rights that are held for the purpose of sale after
      capital appreciation, buildings that have been already been leased out, etc.

      Investment properties of the Company are measured initially at cost upon acquisition, and subject to depreciation or
      amortisation in the relevant periods according to the relevant provisions on xed assets or intangible assets.

      The Company adopts the cost model for subsequent measurement of the investment properties. The method for asset
      impairment provision is set out in note III. 22.

      The balance after the disposal income from the disposal, transfer, scrapping or destruction of the investment properties deducts
      the book value and the relevant taxes shall be recorded into the prot and loss for the current period.




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16. Fixed asset
(1). Conditions for recognition of xed assets
     √ Applicable □ N/A

    The Company's xed assets represent the tangible assets held by the Company using in the production of goods, rendering of
    services, rent and for operation and administrative purposes with useful life over one year.
    The fixed asset can be recognised only when the economic benefit related to the fixed asset is probable to flow into the
    company and the cost of the xed asset can be reliably measured.

    The Company's xed assets are initially measured at the actual cost at the time of acquisition.

(2). Method of depreciation
     √ Applicable □ N/A


                                                                                  Useful years             Annual             Residual
     Category                                 Depreciation methods
                                                                                        (year)         depreciation             rate %
     Properties and Buildings            Equal annual instalment method                     20        4.5%-4.75%              5%-10%
     Machine and equipment               Equal annual instalment method                     10            9%-9.5%             5%-10%
     Transportation Equipment            Equal annual instalment method                      5           18%-19%              5%-10%
     Electric equipment and others       Equal annual instalment method                   5-10           18%-19%              5%-10%


    Where, for the fixed assets for which depreciation provision is made, to determine the depreciation rate, the accumulated
    amount of the xed asset depreciation provision that has been made shall be deducted.

(3). The impairment testing and the impairment provision of xed assets
     Refer to note III. 22 for the impairment testing and the impairment provision of xed assets.

(4). Recognition basis, valuation and depreciation method of nancial leased xed assets
     √ Applicable □ N/A

    When the Company's leased fixed assets meet one or more of the following criteria, it is recognized as finance leased fixed
    assets:
    ① At the expiration of the lease term, the ownership of the leased assets is transferred to the Company.
    ② The Company has the option to purchase leased assets. The agreed purchase price is expected to be much lower than the
        fair value of the leased asset when the option is exercised. Therefore, it can be reasonably determined that the Company
        will exercise this option on the lease start date.
    ③ Even if the ownership of the asset is not transferred, the lease term occupies most of the useful life of the leased asset.
    ④ The present value of the Company's minimum lease payment on the lease start date is almost equivalent to the fair value of
       the leased assets on the lease start date.
    ⑤ The leased assets are of special nature, and only our company can use them if they don't undergo major transformation.

    For xed assets leased by nance leases, the lower of the fair value of the leased assets on the lease start date and the present
    value of the minimum lease payment shall be the entry value. The minimum lease payment is taken as the entry value of the
    long-term payable, and the difference is taken as the unrecognized financing expense. In the process of lease negotiation and
    signing of the lease contract, the initial direct costs attributable to the lease item, such as handling fees, attorney fees, travel
    expenses, stamp duty, etc., are included in the value of the leased asset. The unrecognized nancing costs shall be amortized by
    the eective interest method during each period of the lease term.

    The fixed assets acquired by finance lease adopt the same policy as self-owned fixed assets to calculate the depreciation of
    leased assets. If it can be reasonably determined that the ownership of the leased asset will be obtained at the end of the lease
    term, depreciation shall be accrued within the useful life of the leased asset; if it cannot be reasonably determined that the
    ownership of the leased asset will be obtained at the end of the lease term, the leased asset is still usable during the lease term
    Depreciation is accrued in the shorter of the two years.



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(5). The Company reviews the useful life and estimated net residual value of fixed asset and the depreciation method applied
     annually at each of the period end.

      The useful lives of xed asset are adjusted if their expected useful lives are dierent from the original estimates; the estimated
      net residual values are adjusted if they are dierent from the original estimates.

(6). Overhaul costs

      The overhaul costs occurred in regular inspection of f are recognised in the cost of property, plant and equipment if there
      is undoubted evidence to confirm that they meet the recognition criteria of fixed assets, otherwise, the overhaul costs are
      recognised in profit or loss for the current period. Property, plant and equipment are depreciated during the intervals of the
      regular overhaul.


17. Construction in progress
      √ Applicable □ N/A

      Construction in progress is measured at actual cost. Actual cost comprises necessary project expenditure incurred during
      construction, borrowing cost that are eligible for capitalisation and other necessary cost incurred to bring the xed assets ready
      for their intended use.

      Construction in progress is transferred to xed assets when the assets are ready for their intended use.

      For provision for impairment of construction in progress, refer to note III. 22.

      In the balance sheet, the ending balance of construction materials is presented under“construction in progress”.


18. Borrowing costs
      √ Applicable □ N/A

 (1) Recognition principle of capitalisation of borrowing costs

      For borrowing costs that are directly attributable to the acquisition, construction or production of a qualifying asset, they shall
      be capitalised and included in the cost of related assets; other borrowing costs are recognised as expenses and included in prot
      or loss when incurred. Capitalisation of such borrowing costs can commence only when all of the following conditions are
      satised:
      ① Expenditures for the asset incurred, capital expenditure includes the expenditure in the form of cash payment, transfer
          of non-cash assets or the interest bearing liabilities for the purpose of acquiring or constructing assets eligible for
          capitalisation;
      ② Borrowing costs incurred;
      ③ Activities relating to the acquisition, construction or production of the asset that are necessary to prepare the asset for its
          intended use or sale have commenced.

 (2) Capitalisation period of borrowing costs

      Capitalisation of such borrowing costs ceases when the qualifying assets being acquired, constructed or produced become
      ready for their intended use or sale. The borrowing cost incurred after that is recognised as an expense in the period in which
      they are incurred and included in prot or loss for the current period.

      Capitalisation of borrowing costs is suspended during periods in which the acquisition, construction or production of a
      qualifying asset is interrupted abnormally and when the interruption is for a continuous period of more than 3 months; the
      borrowing costs in the normally interrupted period continue to capitalise.

 (3) Calculation of the capitalisation rate and amount of borrowing costs

      The interest expense of the specific borrowings incurred at the current period, deducting any interest income earned from
      depositing the unused specific borrowings in bank or the investment income arising from temporary investment, shall be
      capitalised. The capitalisation rate of the general borrowing is determined by applying the weighted average eective interest



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    rate of general borrowings, to the weighted average of the excess amount of cumulative expenditures on the asset over the
    amount of specic borrowings.

    During the capitalisation period, exchange differences on foreign currency special borrowings shall be capitalised; exchange
    dierences on foreign currency special borrowings shall be recognised as current prots or losses.


19. Biological assets
    √ Applicable □ N/A

(1) Determination of biological assets

    Biological assets refer to assets comprising living animals and plants. No biological asset shall be recognised unless it meets
    the conditions as follows simultaneously:
    ① An enterprise possesses or controls the biological asset as a result of past transaction or event;
    ② The economic benets or service potential concerning this biological asset are likely to ow into the enterprise;
    ③ The cost of this biological asset can be measured reliably.

(2) Classication of biological assets

    The Company's biological assets are consumable biological assets which include traditional Chinese medical herbal plant
    species.

    The consumable biological assets refer to the biological assets held for sale, or biological assets to be harvested as agricultural
    products in the future, consisting of growing traditional Chinese medical herbal plant species. The consumable biological
    asset is initially measured at cost. The cost of any consumable biological assets by way of self-planting, self-cultivating, self-
    breading is the necessary cost directly attributable to this asset prior to the harvest, consisting of borrowing costs that meet
    the conditions of capitalisation. The subsequent expenses for the maintenance, protection and cultivation of a consumable
    biological asset after the harvest shall be included in the current prots or loss.

    The cost of a consumable biological asset shall, at the time of harvest or sale, be carried over at its book value by the weighted
    average method.

(3) Impairment of biological assets

    If the net realisable value of the consumable biological assets is lower than their carrying amount, provision of impairment loss
    is made and recognised in the profit or loss for the current period as the excess of the carrying amount over the net realisable
    value. If the factors aecting the impairment of consumable biological assets no longer exist, the amount of write-down shall
    be resumed and shall be reversed from the original provision for the impairment loss before being recognised in the profit or
    loss for the current period.


20. Intangible assets
(1). Pricing methods, useful lives and impairment tests
     √ Applicable □ N/A

    An intangible asset is an identiable non-monetary asset without physical substance owned or controlled by the Company. An
    intangible asset is recognised only when all of the following conditions are satised: It is probable that the economic benets
    associated with the intangible assets will flow to the enterprise; The cost of the intangible asset can be reliably measured.
    Intangible assets are initially measured at actual cost.

    The Company's intangible assets include land use rights, patents and proprietary technologies, software, trademark rights, etc.

    Intangible assets are initially measured at historical cost, and the Company shall make judgement to determine the useful
    life of intangible assets upon acquisition. Intangible assets with finite useful life are amortised in the profit or loss over the
    estimated useful life, using the method that reects the expected realisation of economic benets associated with the asset, and
    if the expected realisation cannot be reliably determined, it is amortised using the straight-line method. Intangible assets with
    indenite useful life is not amortised.


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      Amortisation of intangible assets with nite useful life is as follows:


      Category                                Expected useful life
      Land use rights                         The useful life specied in the land use right certicate
      Patent and technical know-how           Protection period or benet period stipulated by relevant national laws and regulations
      Trademark rights                        Ten years
      Others                                  Benet period


      The useful life for an intangible asset with a nite useful life and the method of amortisation are reviewed at least once at the
      end of each financial year. If the useful life and amortisation method for the intangible assets are different from the previous
      estimate, the change of amortisation is recognised prospectively as the change of accounting estimate.

      When the Company estimates an intangible asset can no longer bring future economic benets to the Company at the end of a
      period, the carrying amount in which should be reversed to prot or loss for the current period.

      Please refer to note III. 22 for the provision of impairment of intangible assets.


21. Research and development expenditures
      √ Applicable □ N/A

      Expenditures on an internal research and development project are classified into expenditures on the research phase and
      expenditures on the development phase.

      Expenditures on the research phase shall be recognised in prot or loss for the current period when incurred.

      Expenditures on the development phase will be capitalised only when all of the following conditions are satisfied: it is
      technically feasible to complete the intangible asset so that it will be available for use or sale; the Company intends to complete
      the intangible asset and use or sell it; it can be demonstrated how the intangible asset will generate economic benefits,
      including proving that the intangible assets or the products produced by it will have markets, or the intangible assets for
      internal use will be useful; there are adequate technical, financial and other resources to complete the development and the
      Company is able to use or sell the intangible assets; and expenditures on the development phase attributable to the intangible
      assets can be reliably measured. The development expenditures that do not satisfy the above conditions shall be recognised in
      prot or loss for the current period.

      Our research and development projects enter the development stage after meeting the above conditions and forming the project
      throught the technical and economic feasibility studies.

      Capitalised expenditures on the development phase are shown as development expenditures on the balance sheet and
      reclassied as intangible assets on the date the project meets the intended purpose.

      Capitalisation conditions for specic research and development projects are as follows:
      ① For research and development projects that are not required to obtain clinical approvals, the period from the beginning of
         research and development to the pilot phase is treated as the research phase, and all expenditures shall be recognised in
         prot or loss for the current period when incurred; the period from the pilot phase to the obtaining of production approvals
         is treated as the development phase, and all expenditures shall be recognised as development expenditures and reclassied
         as intangible assets after the obtaining of production approvals.
      ② For research and development projects that require clinical approval, the period from the beginning of research and
         development to the obtaining of clinical approval is treated as the research phase, and all expenditures incurred shall be
         recognised in profit or loss for the current period when incurred; the period from the obtaining of clinical approval to
         the obtaining of production approval is treated as the development phase, and the expenditures shall be recognised as
         development expenditures and reclassied as intangible assets after the obtaining of production approval.
      ③ External technology transfer fees and the cost of purchasing clinical approvals can be recognised directly as development
         expenditures, and subsequent expenditures are accounted for in accordance with ① and ② above.



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   ④ The Company reviews the latest research and development status of each project at the end of each year and if the research
      and development project no longer qualifies for the development stage, the corresponding development expenditure are
      recognised in prot or loss for the current period.
   ⑤ Where it is impossible to differentiate the expenditures on the research phase and the expenditures on the development
      phase, all the research and development expenditures are recognised in prot or loss for the current period.

    Please refer to note III.22 for the impairment testing methodology and impairment provision for intangible assets.


22. Impairment of assets
    √ Applicable □ N/A

    The impairment of subsidiaries, associates and joint ventures in the long-term equity investments, investment properties
    subsequently measured at cost, fixed assets, construction in progress, right-of-use assets, intangible assets, etc. (Excluding
    inventories, investment properties measured at fair value, deferred income tax assets and financial assets) are determined as
    follows:

    At the balance sheet date, the Company determines whether there may be evidence of impairment, if there is any, the Company
    will estimate the recoverable amount for impairment, and then test for impairment. For goodwill arising from a business
    combination, intangible assets with indenite useful life and the intangible assets that have not yet ready for use are tested for
    impairment annually regardless of whether such evidence exists.

   The recoverable amount of an asset is determined by the higher amount of fair value deducting disposal costs and net present
   value of future cash flows expected from the assets. The Company estimates the recoverable amount based on individual
   asset; for individual asset which is difficult to estimate the recoverable amount, the recoverable amount of the asset group is
   determined based on the asset group involving the asset. The identication of the asset group is based on whether the cash ow
   generated from the asset group is independent of the major cash inows from other assets or asset groups.

    When the asset or asset group's recoverable amount is lower than its carrying amount, the Company reduces its carrying
    amount to its recoverable amount, the reduced amount is included in prot or loss, while the provision for impairment of assets
    is recognised.

    In terms of impairment test of the goodwill, the carrying amount of the goodwill, arising from business combination, shall
    be allocated to the related asset group in accordance with a reasonable basis at acquisition date. Those that are difficult to be
    allocated to related assets shall be allocated to related asset group. Related assets or assets group refer to those that can benet
    from the synergies of business combination and are not larger than the Company's recognised reporting segment.

    When there is an indication that the asset and asset group are prone to impair, the Company should test for impairment for
    asset and asset group excluding goodwill and calculate the recoverable amount and recognise the impairment loss accordingly.
    The Company should test for impairment for asset or the asset group including goodwill and compare the asset or asset group's
    recoverable amount with its carrying amount, provision for impairment of assets shall be recognised when the recoverable
    amount of assets is lower than its carrying amount.

    Once impairment loss is recognised, it cannot be reversed in subsequent accounting periods.


23. Long-term deferred expenses
    √ Applicable □ N/A

    The Company's long-term deferred expenses measured at cost actually incurred and evenly amortised on straight-line basis
    over the expected beneficial period. For the long-term deferred expense items that cannot benefit in subsequent accounting
    period, their amortised value is recognised through prot or loss.




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24. Employee compensation
(1)、The scope of employee compensation

      Employee compensation are all forms of remuneration and compensation given by the Company in exchange for service
      rendered by employees or the termination of employment. Employee compensation include short-term employee
      compensation, post-employment benefits, termination benefits and other long-term employee benefits. Employee
      compensation include benefits provided to employees' spouses, children, other dependants, survivors of the deceased
      employees or to other beneciaries.

      According to liquidity, employment compensations are presented separately as“accrued payroll”item and“long-term
      employment compensation payable”item in the balance sheet.

(2)、Short-term employee compensation
     √ Applicable □ N/A

      During the accounting period in which the employees render the related services, wages, bonuses, social security contributions
      (including medical insurance, injury insurance, maternity insurance, etc.) and house funding are recognised as liability and
      included in the prot or loss for the current period or related asset costs. If the liability cannot be wholly settled within twelve
      months after the end of the annual reporting period in which the employees render the related service and have significant
      nancial impact, the liability shall be measured as the discounted amounts.

(3)、Post-employment benets
     √ Applicable □ N/A

      Post-employment benefit plans mainly includes defined contribution plans and defined benefit plans. Defined contribution
      plans include the basic pension insurance, unemployment insurance, etc., and the contributions to defined contribution plans
      are recognised and included in prot or loss for the current period or related asset costs.

(4)、Termination benets
     √ Applicable □ N/A

      The liability of employee compensation arising from termination benefits is recognised and included in profit or loss for the
      current period in the earlier date of the followings: The Company cannot unilaterally withdraw the oer of termination benets
      because of an employment termination plan or a curtailment proposal; the Company recognises costs or expenses related to the
      restructuring that involves the payment of termination benets.

      For the implementation of the internal retirement plan for employees, the economic compensation before the ocial retirement
      date is a termination benefit. The wage of and social insurance contributions for the internally retired employee which would
      have incurred from the date on which the employee cease rendering services to the Company to the scheduled retirement date
      will be included in the profit or loss for the current period. Economic compensation after the official retirement date (such as
      normal pension) should be treated as post-employment benets.

(5)、Other long-term employee benets
     √Applicable □ N/A

      When other long-term employee benefits provided to the employees by the Company are satisfied the conditions of a defined
      contribution plan, those benefits shall be accounted for in accordance with the relevant provisions of the above defined
      contribution plans. When the benefits are satisfied the conditions of a defined benefit plan, those benefits shall be accounted
      for in accordance with the relevant provisions of the above dened benet plans, except that the“change in remeasurement of
      the net liability or net assets of the dened benet plans”in the cost of the related employee compensation shall be included in
      prot or loss for the current period or related asset costs.


25. Provisions
      √ Applicable □ N/A




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     An obligations related to a contingency is recognised as a provision when all of the following conditions are satised:

     (1) The obligation is a present obligation of the Company;

     (2) It is probable that an outow of economic benets will be required to settle the obligation;

     (3) The amount of the obligation can be measured reliably.

     Provisions are initially measured at the best estimate of the payment to settle the associated obligations and consider the
     relevant risk, uncertainty and time value of money. If the impact of time value of money is significant, the best estimate is
     determined as its present value of future cash outow. The Comapany reviews the carrying amount of provisions at the balance
     sheet date and adjusts the carrying amount to reect the best estimate.

     If the expenses for clearing of provisions is fully or partially compensated by a third party, and the compensated amount can
     be definitely received, it is recognised separately as asset. The compensated amount recognised shall not be greater than the
     carrying amount of the liability recognised.


 26. Share-based payment and equity instruments
      √ Applicable □ N/A

(1)Accounting treatment of share-based payment

     Share-based payments are transactions in which equity instruments are granted or liabilities are assumed on the basis of equity
     instruments in order to obtain services from employees or other parties. Share-based payment is classified into equity-settled
     share-based payment and cash-settled share-based payment.

 ① Equity-settled share-based payment

     Equity-settled share-based payment is measured at the fair value of the equity instruments granted to employees. If vesting is
     conditional upon completion of services in the pending period or fulllment of performance conditions, at each balance sheet
     date during the pending period, based on the best estimates of the number of vested equity instruments, the services received
     for the period are recognised as the costs or expenses on a straight-line basis. Instruments which are vested immediately upon
     the grant are included in relevant costs or expenses at the fair value of equity instruments on the date of grant and capital
     reserves are increased accordingly.

     At each balance sheet date during the pending period, the Company makes the best estimate and revises the number of
     equity instruments expected to be exercisable based on subsequent information such as changes in the number of exercisable
     employees obtained from the latest available information. The eect of the above estimates is recognised as the relevant cost or
     expense in the current period, and capital surplus is adjusted accordingly.

     For the equity instruments granted under an equity-settled share-based payment for services from other parties, if the fair value
     of services received from other parties can be measured reliably, the fair value of the equity instruments is measured at the fair
     value of services from other parties on the grant date; if the fair value of services received from other parties cannot be measured
     reliably but the fair value of the equity instruments can be measured reliably, the fair value of the equity instruments on the date on
     which services are received shall be recognised as related costs or expenses, with a corresponding increase in owners' equity.

 ② Cash-settled share-based payment

     Cash-settled share-based payments are measured at the fair value of the liabilities (share-based or other equity instrument-based)
     assumed by the Company. Instruments which are vested immediately upon the grant are included in relevant costs or expenses
     at the fair value of liabilities assumed by the Company on the date of grant and liabilities are increased accordingly. If vesting is
     conditional upon completion of services in the pending period or fulllment of performance conditions, at each balance sheet date
     during the pending period, based on the best estimates of the vesting situation, the services received for the period are recognised
     as the costs or expenses and corresponding liabilities at fair value of the liabilities assumed by the Company.

     At each balance sheet date and settlement date before the relevant liabilities are settled, the fair value of liabilities is re-
     measured and the resulting changes are included in the prot and loss for the current period.



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(2)Accounting treatment for amendment and termination of share-based payments

      When the Company modifies the share-based payment plan, and if such modification increases the fair value of the equity
      instruments granted, the increase in services received will be recognised accordingly following the increase in fair value of
      the equity instruments; if such modification increases the number of equity instruments granted, the increase in fair value of
      the equity instruments is recognised as a corresponding increase in service achieved. The increase in fair value of the equity
      instruments refers to the difference in fair value on the date of modification before and after the modification in respect of
      the equity instruments. If the modification reduces the total fair value of the share-based payments or adopts any form that
      is unfavorable to employees to modify the terms and conditions of the share-based payment plan, accounting treatment will
      be continued to be conducted in respect of the services received and the modication will be deemed to have never occurred,
      unless the Company had cancelled part or all of the equity instruments granted.

      During the pending period, if the equity instruments granted are cancelled (except for failure to meet the non-market conditions
      of the vesting conditions), the Company will undertake an accelerated vesting in respect of the cancelled equity instruments
      that had been granted, include the remaining amount that shall be recognised during the pending period in the current profit
      and loss immediately and recognise capital reserve accordingly. Where employees or other parties are permitted to choose
      to fulfill non-vesting conditions but have not fulfilled during the pending period, the Company will treat the granted equity
      instruments as cancelled.

 (3) Accounting treatment for share-based payments involving the Company and the shareholders or the de facto controller of the
     Company

      For share-based payment transactions involving the Company and the shareholders or the de facto controller of the Company,
      the settlement enterprise and the enterprise receiving services (one under the Company while another external to the Company)
      shall follow the requirements below to conduct accounting treatment in the Company's consolidated nancial statements:

 ① For settlement enterprises settling through their own equity instruments, such share-based payment transaction will be treated
    as equity-settled share-based payment; except for this, such share-based payment transaction will be treated as cash-settled
    share-based payment.

      Where a settlement enterprise is an investor of an enterprise receiving services, the fair value of the equity instruments on
      the date of grant or the fair value of the liabilities that shall be assumed are recognised as long-term equity investment in the
      enterprise receiving services, at the same time, capital reserve (other capital reserve) or liabilities are recognised.

 ② Where an enterprise receiving services has no settlement obligations or grants its own equity instruments to employees,
    such share-based payment transaction will be treated as equity-settled share-based payment; where an enterprise receiving
    services has settlement obligations and grants equity instruments (other than its own) to employees, such share-based payment
    transaction will be treated as cash-settled share-based payment.

      For a share-based payment transaction occurring among enterprises under the Company where the enterprise receiving services
      and the settlement enterprise are not the same enterprise, such share-based payment transaction shall be recognised and
      measured in each of the respective financial statements of the enterprise receiving services and the settlement enterprise by
      reference to the above principles.


 27. Preferred shares, perpetual bonds and other financial instruments
      √ Applicable □ N/A

 (1) Classication of nancial liabilities and equity instruments

      The Company classies the nancial instrument or its components as nancial assets, nancial liabilities or equity instruments
      at the initial recognition based on the contract terms of the issued nancial instrument and the economic substance it reects,
      instead of only in legal form, and combine the denition of nancial assets, nancial liabilities and equity instruments.




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(2) Accounting treatment of preferred shares, perpetual bonds and other nancial instruments

    The financial instruments issued by the Company are initially recognised and measured in accordance with the financial
    instrument standards; thereafter, interest or dividends are accrued or distributed on each balance sheet date and processed in
    accordance with relevant specic accounting standards for enterprises. That is, on the basis of the classication of the nancial
    instrument issued, the accounting treatment of interest expenses or dividend distributions of the instrument is determined.
    For financial instruments classified as equity instruments, interest expenses or dividend distributions are treated as profit
    distribution of the Company, and repurchases and cancellations are treated as changes in equity; for financial instruments
    classified as financial liabilities, interest expenses or dividend distributions are in principle treated according to borrowing
    costs, and gains or losses arising from repurchase or redemption are credited to prot or loss for the current period.

    The transaction costs such as charges and commissions incurred by the Company when issuing financial instruments, if
    classified as debt instruments and measured at amortised cost, are included in the initial measurement amount of the issued
    instrument; if classied as equity instruments, are deducted from equity.


28. Income
    √ Applicable □ N/A

    The Company shall recognise revenue when the Company satisfies the performance obligation of the contract, that is, the
    customer obtains control of relevant goods or services.

    When the contract contains two or more performance obligations, on the eective date of the contract, the Company allocates
    the transaction price to each performance obligation based on the percentage of respective unit price of a good or service
    guaranteed by each performance obligation, and the revenue is measured according to the transaction price allocated to each
    performance obligation.

    If one of the following conditions is fullled, the Company satises a performance obligation over time; otherwise, it satises
    a performance obligation at a point in time:
    ① When the customer simultaneously receives and consumes the benefits provided by the Company when the Company
        performs its obligations under the contract.
    ② When the customer is able to control the commodity in progress in the course of performance by the Company under the
        contract.
    ③ The product produced by the Company under the contract is irreplaceable and the Company has the right to payment for
        performance completed to date during the term of the contract.

    For a performance obligation satisfied over time, the Company shall recognise revenue over time by measuring the process
    towards complete satisfaction of the performance obligation. When the progress of performance cannot be reasonably
    determined, if the costs incurred by the Company are expected to be recoverable, the revenue will be recognised to the extent
    of the costs incurred until the progress of performance can be reasonably determined.

    For a performance obligation satisfied at a point in time, the Company shall recognise revenue when the customer obtains
    control of relevant goods or services. When determining whether the customer has obtained control of the goods and services,
    the Company will consider the following indications:
    ① The Company has the current right to receive payment for the goods or services, which is when the customers have the
        current payment obligations for the goods.
    ② The Company has transferred the legal title of the goods to the client, which is when the client possesses the legal title of
         the goods.
    ③   The Company has transferred the physical possession of goods to the customer, which is when the customer obtains
         physical possession of the goods.
    ④   The Company has transferred all of the substantial risks and rewards of ownership of the goods to the customer, which is
         when the client obtains all of the substantial risks and rewards of ownership of the goods to the customer.
    ⑤   When the customer has accepted the goods or services.
    ⑥   When other information indicates that the customer has obtained control of the goods.



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       A contract asset represents the Company's right to consideration in exchange for goods or services that it has transferred to
       a customer when that right is conditioned on factors other than passage of time, for which the loss allowances for expected
       credit loss is recognised (see Note III.10(6)). The Company shall present any unconditional (i.e. if only the passage of time is
       required) rights to consideration separately as a receivable. A contract liability is the Company's obligation to transfer goods or
       services to a customer for which the Company has received consideration (or the amount is due) from the customer.

       The contract assets and liabilities under the same contract shall be shown on a net basis. If the net amount stated in debit
       balance, it will be presented under the items of“Contract assets”or“Other non-current assets”according to its mobility; If
       the net amount stated in credit balance, it will be presented under the items of“Contract liabilities”or“Other non-current
       liabilities”according to its mobility.

       The Company enters into sales contracts with customers. Revenue from sales is recognised according to the invoiced amount
       upon the delivery of goods to the designated carrier or purchaser according to the orders received from customers; revenue
       from export sales is recognised mainly by adopting FOB mode according to custom declaration upon making declaration for
       goods and completing the export procedures.


29. Contract costs
       √ Applicable □ N/A

       Contract costs are either the incremental costs of obtaining a contract with a customer or the costs to fulfil a contract with a
       customer.

       Incremental costs of obtaining a contract are those costs that the Company incurs to obtain a contract with a customer that it
       would not have incurred if the contract had not been obtained e.g. an incremental sales commission. The Company recognises
       as an asset the incremental costs of obtaining a contract with a customer if it expects to recover those costs. Other costs of
       obtaining a contract are expensed when incurred.

       If the costs to fulfil a contract with a customer are not within the scope of inventories or other accounting standards, the
       Company recognises an asset from the costs incurred to full a contract only if those costs meet all of the following criteria:
       ① The costs relate directly to an existing contract or to a specically identiable anticipated contract, including direct labour,
            direct materials, allocations of overheads (or similar costs), costs that are explicitly chargeable to the customer and other
           costs that are incurred only because the Company entered into the contract;
       ② The costs generate or enhance resources of the Company that will be used in satisfying (or in continuing to satisfy)
           performance obligations in the future;
       ③ The costs are expected to be recovered.

        Assets recognised for the incremental costs of obtaining a contract and assets recognised for the costs to fulfil a contract (the
      “assets related to contract costs”) are amortised on a systematic basis that is consistent with the transfer to the customer of the
        goods or services to which the assets relate and recognised in prot or loss for the current period.

       The Company recognises an impairment loss in profit or loss to the extent that the carrying amount of an asset related to
       contract costs exceeds:
       ① Remaining amount of consideration that the Company expects to receive in exchange for the goods or services to which
           the asset relates;
       ② The cost estimated to be happened for the transfer of related goods or services.

       The costs of contract performance recognised as assets, if the amortisation period is less than one year or a normal operating
       cycle upon the initial recognition, are presented as“Inventories”item, and if the amortisation period is more than one year or a
       normal operating cycle upon the initial recognition, are presented as“Other non-current assets”item.

       The contract obtaining costs recognised as assets, if the amortisation period is less than one year or a normal operating cycle
       upon the initial recognition, are presented as“Other current assets”item, and if the amortisation period is more than one year
       or a normal operating cycle upon the initial recognition, are presented as“Other non-current assets”item.




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30. Government grants
    √ Applicable □ N/A

    A government grant shall be recognised only when the enterprise can comply with the conditions attaching to the grant and the
    enterprise can receive the grant.

    If a government grant is in the form of a transfer of a monetary asset, the item is measured at the amount received. If a
    government grant is in the form of a transfer of a non-monetary asset, the item is measured at fair value, when fair value is not
    reliably determinable, the item is measured at a nominal amount of RMB1.

    Government grant related to assets represents the government grant received for acquisition and construction of long term
    assets, or forming long term assets in other ways. Except for these, all are government grant related to income.

    Regarding to the government grant not clearly defined in the official documents and can form long term assets, the part of
    government grant which can be referred to the value of the assets is classified as government grant related to assets and the
    remaining part is government grant related to income. For the government grant that is difficult to distinguish, the entire
    government grant is classied as government grant related to income.

    The government grant related to assets is recognised as deferred income and would be transferred to prot or loss in reasonable
    and systematic manner within the period of use of the relevant assets. The government grant related to income which is
    used to compensate the relevant costs or losses incurred should be recognised in the profit or loss for the current period; the
    government grant related to income which is used to compensate the relevant costs or losses for the subsequent period is
    recognised as deferred income and shall be recognised in profit or loss during the relevant cost or loss confirmation period.
    Government grants measured in nominal terms are directly included in the prot or loss for the current period. The Company
    has adopted a consistent approach to the same or similar government grant business.

    The government grants related to daily activities are recognised as other gains in accordance with the substance of economic
    business. Government grants that are not related to daily activities are recognised as non-operating income and expenses.

    If the recognised government grants need to be refunded, adjust the carrying amount of assets when the carrying amount of
    assets is offset at the time of initial recognition; the balance of deferred income is offset against the carrying amount of the
    balance of deferred income and the excess is recognised in the profit or loss for the current period. Other circumstances, it is
    directly recognised in the prot or loss for the current period.


31. Deferred tax assets and deferred tax liabilities
    √ Applicable □ N/A

(1) Current tax

    At the balance sheet date, for the current tax liabilities (or assets) arising from the current period and the previous period,
    should be measured by the tax of the estimated payable (returnable) amount which be calculated according to the regulations
    of the tax law. The amount of the tax payable which is based by the calculation of the current tax expenses, are according to the
    result measured from the corresponding adjustment of the pre-tax accounting prot of the current period which in accord to the
    relevant regulations of the tax law.

(2) Deferred tax assets and deferred tax liabilities

    The difference between the carrying amount of an asset or liability and its tax basis, as well as the temporary differences
    arising from differences between the carrying amount and tax basis of items that are not recognised as assets and liabilities
    but in accordance with the tax law, can be recognised as deferred tax assets and deferred tax liabilities by adopting the balance
    sheet liability method.




                                                                                                                                179
      No deferred tax liability is recognised for a temporary difference arising from the initial recognition of goodwill the initial
      recognition of assets or liabilities due to a transaction other than a business combination, which affects neither accounting
      profit nor taxable profit (or deductible loss). Besides, no deferred tax assets well be recognised for the taxable temporary
      differences related to the investments in subsidiaries, associates and joint ventures, if the Company can control the time
      of the reverse of temporary differences as well as the temporary differences are unlikely to be reversed in the foreseeable
      future. Except for the above exceptions, the Company recognises all deferred income tax liabilities arising from other taxable
      temporary dierences.

       The deductible temporary dierences the initial recognition of assets or liabilities arising from transactions that are neither a
      business combination, nor do they affect accounting profits and taxable income (or deductible losses), will not be recognised
      as related deferred income tax assets. In addition, as for the taxable temporary differences associated with investments in
      subsidiaries, associates and joint ventures, if the Company is able to control the timing of the reversal of the temporary
      differences, and the temporary differences may not be reversed in the foreseeable future, the related deferred income tax
      assets will also not be recognised. Except for the above exceptions, the Company recognises a deferred tax asset arising from
      other deductible temporary dierences, to the extent that it is probable that taxable income will be available against which the
      deductible temporary dierences.

      The Company recognises a deferred tax asset for the carry-forward of deductible losses and tax credits to subsequent periods,
      to the extent that it is probable that future taxable prots will be available against which deductible losses and tax credits can
      be utilised.

      At the balance sheet date, deferred tax assets and deferred tax liabilities are measured at the tax rates that are expected to apply
      to the period when the asset is realised or the liability is settled in accordance with the provisions of the tax law.

      At the balance sheet date, the Company reviews the carrying amount of a deferred tax asset. If it is probable that sufficient
      taxable profits will not be available in future periods to allow the benefit of the deferred tax asset to be utilised, the carrying
      amount of the deferred tax asset is reduced. Any such reduction in amount is reversed when it becomes probable that sucient
      taxable prots will be available.

(3) Tax expenses

      The tax expenses comprise current tax and deferred tax.

      The rest current tax and deferred tax expenses or revenue should be included into current gains and losses expect for the
      current tax and the deferred tax related to the transaction and events that be confirmed as other comprehensive income or be
      directly included in the shareholders' equity which should be included in other comprehensive income or shareholders' equity
      as well as the book value for adjusting the goodwill of the deferred income tax occurs from the business combination.

 (4) Oset of tax

      The current tax assets and liabilities of the Company should be listed by the written-off net amount which intend to executes
      the net amount settlement as well as the assets acquiring and liabilities liquidation at the same time while owns the legal rights
      of settling the net amount.

      The deferred tax assets and liabilities of the Company should be listed as written-o net amount when having the legal rights
      of settling the current tax assets and liabilities by net amount and the deferred tax and liabilities is relevant to the tax which
      be collected from the same taxpaying bodies by the same tax collection and administration department or is relevant to the
      dierent taxpaying bodies but during each period which there is signicant reverse of the deferred income assets and liabilities
      in the future and among which the involved taxpaying bodies intend to settle the current income tax and liabilities by net
      amount or are at the same time acquire the asset as well as liquidate the liabilities.


32. Leases
      √ Applicable □ N/A




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(1) Identication of leases

    At the inception of a contract, the Company, as a lessee or lessor, assesses if the customer in a contract has the right to obtain
    substantially all the economic benets from use of the identied assets and the right to direct the use of the identied assets in
    the period of use. The Company would identify that a contract is a lease, or contains a lease if a party of the contract transfers
    the right to control the use of one or more identied assets for a period of time in exchange for consideration.

(2) The Company as the lessee

    At the inception of a lease, the Company recognises all its leases as the right-of-use assets and lease liabilities, except for the
    short-term leases and the leases of low-value assets which are treated with a simplied approach.

    For the accounting policies on the right-of-use assets, please refer to Note III.33.

    Lease liabilities are initially measured based on the present value of outstanding lease payment at the inception of a lease,
    discounted using the interest rate implicit in the lease or the incremental borrowing rate. Lease payment include: fixed
    payments and in-substance xed payments, less any lease incentives (if there is a lease incentive); variable lease payment that
    are based on an index or a rate; the exercise price of a purchase option if the lessee is reasonably certain to exercise that option;
    payments of penalties for terminating the lease option, if the lease term reflects that the lessee will exercise that option; and
    amounts expected to be payable under the guaranteed residual value provided by the lessee. The Company shall subsequently
    calculate the interest expenses of lease liabilities over the lease term at the fixed periodic interest rate, and include it into the
    prot or loss for the current period. Variable lease payments not included in the measurement of lease liabilities are charged to
    prot or loss in the period in which they actually arise.

    Short-term lease

    Short-term lease refers to the lease that the lease term does not exceed 12 months from the inception of a lease, and the lease
    that includes the option of purchase is not a short-term lease.

    The Company recognises the amount of lease payments of short-term lease in the cost of the related asset or the prot or loss
    for the current period, on a straight-line method over each period of the lease term.

    Leases of low-value assets

    For the Leases of low-value assets, the Company chooses to adopt the above simplified treatment method in accordance with
    the specic conditions of each lease.

    The Company recognised the lease payments for the leases of low-value assets in the relevant asset cost or the prot or loss for
    the current period on a straight-line basis over each period of the lease term.

(3) The Company as the lessor

    When the Company is the lessor, the lease that substantially transfers all the risks and rewards related to the ownership of
    assets is recognised as a nance lease, and leases other than nance leases are recognised as operating leases.

    Finance leases

    In a financial lease, the Company uses the net investment in leases as the carrying amount of finance lease receivables at the
    inception of a lease. The net investment in leases is the sum of the unguaranteed residual value and the present value of the
    outstanding lease payment at the inception of a lease, discounted using the interest rate implicit in the lease. The Company,
    as the lessor, calculates and recognises the interest income over each period of the lease term at a fixed periodic interest rate.
    Variable lease payments not included in the measurement of the lease liability, which are obtained by the Company as a lessor,
    are recognised in prot or loss as incurred.

     The termination of recognition and impairment of nancial lease receivables is accounted for in accordance with the provisions
     of“Accounting Standards for Business Enterprises No. 22 – Recognition and Measurement of Financial Instrument”and
   “Accounting Standards for Business Enterprises No. 23 – Transfer of Financial Assets”.




                                                                                                                                    181
      Operating leases

      For the rental of operating leases, the Company recognises it in the prot or loss for the current period on a straight- line basis
      over each period of the lease term. The initial direct cost incurred in connection with an operating lease shall be capitalised and
      amortised on the same basis for recognition of rental income during the lease term, and shall be included in installments in the
      profit or loss for the current period. The variable lease payment, which is obtained in connection with an operating lease and
      not included in the lease receivables, shall be included in the prot and loss for the current period when they actually occur.


33. Right-of-use assets
      √ Applicable □ N/A

 (1) Recognition condition of right-of-use assets

      The right-of-use assets of the Company are defined as the right of underlying assets in the lease term for the Company as a
      lessee.

      Right-of-use assets are initially measured at cost as at the commencement date of the lease, which consists of: the amount of
      the initial measurement of the lease liability; any lease payments made at or before the commencement date of the lease less
      any lease incentives received if any; initial direct expenses incurred by the Company as a lessee; costs to be incurred by the
      Company as a lessee in dismantling and removing a leased asset, restoring the site on which it is located or restoring the leased
      assets to the condition required by the terms and conditions of the lease. The Company as a lessee recognises and measures the
      costs of demolition and restoration according to“Accounting Standards for Business Enterprises No.13 – Contingencies”, and
      subsequently adjusts for any remeasurement of lease liability.

 (2) Depreciation method of right-of-use assets

      The Company calculates depreciation on a straight-line basis. Right-of-use assets in which the Company as a lessee is
      reasonably certain to obtain ownership of the underlying leased assets at the end of the lease term are depreciated over the
      remaining useful life. Otherwise, right-of-use assets are depreciated over the shorter of the lease term and its remaining useful
      life.

 (3) For methods of impairment testing and provision for impairment for right-of-use assets, please refer to note III. 22.


34. Repurchase of shares
      Prior to cancellation or transfer of shares repurchased, the Company recognises all expenditures arising from share repurchase
      as cost of treasury shares in the treasury share account. Considerations and transaction fee incurred from the repurchase of
      shares shall lead to the elimination of owners' equity and does not recognise profit or loss when shares of the Company are
      repurchased, transferred or cancelled.

      The difference between the actual amount received and the carrying amount of the treasury stock are recognised as capital
      reserve when the treasury stocks are transferred, if the capital reserve is not sufficient to be offset, the excess amount shall
      be recognised to offset surplus reserve and undistributed profit. When the treasury stocks are cancelled, the capital shall be
      eliminated according to the number of shares and par value of cancellation shares, the difference between the actual amount
      received and the carrying amount of the treasury stock are recognised as capital reserve, if the capital reserve is not sucient
      to be oset, the excess amount shall be recognised to oset surplus reserve and undistributed prot.


35. Restricted Shares
      If the Company grants the Restricted Shares to incentive participants under the Share Options Incentive Scheme, the incentive
      participants subscribe for the shares rst. If the unlocking conditions stipulated in the Share Options Incentive Scheme cannot
      be fulfilled subsequently, the Company repurchases the shares at the predetermined price. If the registration and other capital
      increase procedures for the Restricted Shares issued to employees are completed in accordance with relevant regulations, the
      Company recognises share capital and capital reserve (or capital premium) based on the subscription money received from the
      employees on the grant date; and recognises treasury shares and other payables for repurchase obligation.



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36. Significant accounting judgements and estimates
    √ Applicable □ N/A

    Significant accounting estimates and critical assumptions adopted by the Company are continually evaluated based on
    historical experience and other factors, including expectations of future events that are believed to be reasonable. The
    significant accounting estimates and critical assumptions that have a significant risk of causing a material adjustment to the
    carrying amounts of assets and liabilities within the next accounting year are set out below:

(1) Classication of nancial assets

    Significant judgements involved in determining the classification of financial assets include analysis of business mode and
    characteristics of the contractual cash ows.

    Factors considered by the Company in determining the business model of nancial assets management for a group of nancial
    assets include past experience on how financial asset's performance is evaluated and reported to key management personnel,
    how risks affecting the performance of financial asset are assessed and managed and how managers of related businesses are
    compensated.

    When assessing whether the contractual cash flows of financial assets are consistent with basic lending arrangement, the
    Company adopts the following significant judgements: whether the time distribution or amounts of the principal within the
    duration may change due to early repayment and other reasons; whether the interest includes only the time value of money,
    credit risk, other basic lending risks and the consideration for cost and profit. For example, the amounts of early repayment
    only reect principal unpaid, the interest based on principal unpaid and reasonable compensation paid for early termination of
    a contract.

(2) Measurement of ECL for accounts receivables

    The Company calculates ECL of accounts receivables according to their exposure at default and ECL rate, and determines
    ECL rate based on probability of default and loss given default. When determining ECL rate, the Company adopts data like
    historical credit loss experience in combination with current situation and forward-looking information to adjust historical
    data. When considering forward-looking information, the Company uses indicators including the risk of economic downturn,
    external market environment, technology environment and changes on customer situation. The Company periodically monitors
    and reviews assumptions relevant to the measurement of ECL.

(3) Impairment of goodwill

    The Company evaluates whether goodwill is impaired at least once a year. This requires an estimate of the value in use of the
    asset groups to which the goodwill is allocated. In estimating the value in use, the Company needs to estimate the future cash
    ows generated from the asset groups and also to choose an appropriate discount rate in order to calculate the present value of
    the future cash ows.

(4) Development expenditure

    Determining the amounts to be capitalised requires the management to make assumptions regarding the expected future cash
    ows generated from the relevant assets, discount rates to be applied and the expected period of benets.

(5) Deferred income tax assets

    The deferred income tax assets will be recognised for all unused tax losses to the extent that it is probable that there will be
    sufficient taxable profits against which the loss is utilised. This requires the management to exert numerous judgments to
    estimate the timing and amount of the future taxable prots so as to determine the amount of deferred income tax assets to be
    recognised with reference to the tax planning strategy.




                                                                                                                               183
 (6) Revenue recognition

      As stated in note III. 28, the Company makes the following significant accounting judgements and estimates in terms of
      revenue recognition: identifying customer contracts; estimating the recoverability of the considerations that are entitled to be
      obtained by transferring goods to customers; identifying the performance obligation in the contract; estimating the variable
      consideration in the contract and cumulative revenue recognised where it is highly probable that a signicant reversal therein
      will not occur when the relevant uncertainty is resolved; assessing whether there is a significant financing component in the
      contract; estimating the individual selling price of the individual performance obligation in the contract, etc. The Company
      makes judgments primarily based on historical experiences and works. Changes in these significant judgments and estimates
      may have signicant impacts on the operating income, operating costs, and prot or loss of the current or subsequent periods.

 (7) Determination of the fair value of unlisted equity investment

      The fair value of unlisted equity investments represents the expected future cash flows discounted at the prevailing discount
      rate of items with similar terms and risk characteristics. It requires the Company to estimate the expected future cash ows and
      discount rates, and therefore there is uncertainty. Under limited circumstances, if the information used to determine the fair
      value is insucient, or the possible estimated amount of fair value is widely distributed, and cost represents the best estimate
      of the fair value within such scope, the cost may represent an appropriate estimate of the fair value within such distribution
      scope.


37. Changes in significant accounting policies and accounting estimates and correction to accounting errors
(1). Changes in signicant accounting policies
     □ Applicable √ N/A

(2). Changes in signicant accounting estimates
     □ Applicable √ N/A

(3). Description of adjustments in opening balances of line items in financial statements of the current year due to first
     implementation of new lease standard since 2021
     □ Applicable √ N/A

(4). Description of retrospective adjustments in comparative data in prior periods due to rst implementation of new lease standard
     in 2021
     □ Applicable √ N/A




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IV. Taxation

1. The main taxes and tax rates
   √ Applicable □ N/A


    Tax category                                            Basis of taxation                                   Statutory tax rate
    Value added tax                                         Taxable income                                         3%, 6%, 13%
    Urban maintenance and construction tax                  Turnover tax to be paid                                 1%, 5%, 7%
    Education surcharges                                    Turnover tax to be paid                                          3%
    Local education surcharge                               Turnover tax to be paid                                       Note 1
    Enterprise income tax                                   Turnover tax to be paid                                       Note 2


   Note 1: The Company and its subsidiaries that are incorporated in Zhuhai shall pay local education surcharges that are charged
   as 2% of the turnover tax to be paid. Other subsidiaries shall pay local education surcharges according to the tax rate as
   specied at their places of incorporation on the basis of turnover tax to be paid.

   Note 2: Disclosure of taxpayers (if any) with dierent rates of enterprise income tax
   √ Applicable □ N/A


    Taxpayer                                                                                   Rate of enterprise income tax (%)
    Hong Kong Health Pharmaceutical Industry Company Limited, Livzon
    Pharmaceutical Biotechnology Co., Limited, Lian (Hong Kong) Co., Ltd., Livzon                                              16.5
    Biologics Hong Kong Limited
                                                                                              0 or 12 (Tax rate is 12% where the
                                                                                              taxable income is MOP600,000 or
    Companhia de Macau Carason Limitada, Li Zhu (Macau) Limitada                             more; for those with taxable income
                                                                                                less than MOP600,000, they are
                                                                                                  exempted from income taxes.)
    Shenzhen Taitai Pharmaceutical Co., Ltd, Shenzhen Haibin Pharmaceutical Co.,
    Ltd, Xinxiang Haibin Pharmaceutical Co., Ltd, Jiaozuo Joincare Bio Technological
    Co., Ltd, Shanghai Frontier Health Medicine Technology Co., Ltd, Guangzhou
    Joincare Respiratory Medicine Engineering Technology Co., Ltd, Joincare Haibin
    Pharmaceutical Co., Ltd., Livzon Group, Livzon Group Limin Pharmaceutical
    Manufacturing Factory, Livzon Group Livzon Pharmaceutical Factory, Zhuhai
                                                                                                                                15
    FTZ Livzon Hecheng Pharmaceutical Manufacturing Co., Ltd., Shanghai Livzon
    Pharmaceutical Manufacturing Co., Ltd., Livzon Group Xinbeijiang Pharmaceutical
    Manufacturing Inc., Sichuan Guangda Pharmaceutical Manufacturing Co., Ltd.,
    Zhuhai Livzon Diagnostics Inc., Livzon Group Fuzhou Fuxing Pharmaceutical
    Co., Ltd., Shanghai Livzon Biotechnology Co., Ltd. and Livzon Group (Ningxia)
    Pharmaceutical Manufacturing Co., Ltd.
    Livzon MAB Pharm (US) Inc.                                                                                                  21
    Health Investment Holdings Ltd, JoincarePharmaceutical Group Industry Co.,Ltd.,
    Livzon International Limited, Livzon Biologics Limited, Livzon International                                                 0
    Ventures, Livzon International Ventures I, Livzon International Ventures II.
    Other subsidiaries                                                                                                          25


   Note : Companies registered in the British Virgin Islands and the Cayman Islands are not subject to enterprise income tax




                                                                                                                                185
 2. Tax incentives
      □ N/A

 (1) Preferential value added tax

      In accordance with the Announcement on Value Added Tax on Biological Products Sold by Pharmaceutical Operation
      Enterprises issued by the State Administration of Taxation (Announcement of State Administration of Taxation 2012 No. 20)
      and the Notice of the Ministry of Finance, the General Administration of Customs, the State Administration of Taxation and
      the State Drug Administration on the Value-Added Tax Policies for Anti-Cancer Drugs (Caishui [2018] No. 47), the biological
      products sold by the Company are subject to value added tax at 3% by the simple approach.

 (2) Preferential enterprise income tax

      The Company's subsidiaries, Shenzhen Taitai Phamaceutical Co., Ltd, Shenzhen Haibin Phamaceutical Co., Ltd, Xinxiang
      Haibin Phamaceutical Co., Ltd and Shanghai Frontier Health Medicine Technology Co., Ltd are entitled to enjoy
      preferential income tax policies applicable to high and new technology enterprises since 2020 for a valid period of three
      years. Livzon Group and its subsidiaries, Livzon Group Limin Pharmaceutical Manufacturing Factory, Livzon Group
      Livzon Pharmaceutical Factory, Zhuhai FTZ Livzon Hecheng Pharmaceutical Manufacturing Co. , Ltd., Shanghai Livzon
      Pharmaceutical Manufacturing Co., Ltd., Livzon Group Fuzhou Fuxing Pharmaceutical Co., Ltd. and Sichuan Guangda
      Pharmaceutical Manufacturing Co., Ltd. are entitled to enjoy preferential income tax policies applicable to high and new
      technology enterprises since 2020 for a valid period of three years; Livzon Group Xinbeijiang Pharmaceutical Manufacturing
      Inc. and Zhuhai Livzon Diagnostics Inc. are entitled to preferential income tax policies applicable to high and new technology
      enterprises since 2019 for a valid period of three years; Shanghai Livzon Biotechnology Co., Ltd. has reapplied and recognised
      as the high and new technology enterprises for the Period; Livzon Group (Ningxia) Pharmaceutical Manufacturing Co., Ltd.
      was approved to enjoy the enterprise taxation preference of the Encouraged Industries in Western China. Such companies were
      subject to an enterprise income tax rate of 15% for the Period.

      In accordance with Article 27 of the Enterprise Income Tax Law of the People's Republic of China and Article 86 of the
      Regulations for the Implementation of the Enterprise Income Tax Law of the People's Republic of China, the business of
      planting Chinese herbal medicines engaged by the subsidiaries of the Livzon, Datong Livzon Qiyuan Medicine Co., Ltd. and
      Longxi Livzon Shenyuan Medicine Co., Ltd. are exempted from enterprise income tax.

      According to the preferential tax policies for small low-prot enterprises, the portion of annual taxable income of a small low-
      prot enterprise which does not exceed RMB1 million is subject to enterprise income tax at a tax rate of 2.5%; the portion over
      RMB1 million but not exceeding RMB3 million is subject to enterprise income tax at a tax rate of 10%.


 3. Others
      √ N/A




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V. Notes to the Components of the Consolidated Financial Statements

1. Monetary funds
    √ Applicable □ N/A
                                                                                                              Unit: Yuan Currency: RMB
                                        Balance at End of the Period                     Balance at Beginning of the Period
                                   Amount in                                          Amount in
     Items                                   Translation               Amount in                      Translation          Amount in
                                     foreign                                            foreign
                                                    rate                  RMB                                rate             RMB
                                    currency                                           currency
     Cash on hand:                         --           --          225,179.98                   --            --         197,923.25
     RMB                                   --           --          178,851.99                   --            --         148,845.40
     HKD                            30,607.30      0.8176              25,024.53       30,521.06         0.84164           25,687.74
     USD                              701.00       6.3757               4,469.37            706.00        6.5249             4,606.58
     Euro                            2,033.67      7.2197              14,682.49        2,063.67           8.025           16,560.95
     GBP                              250.00       8.6064           2,151.60                250.00        8.8903           2,222.58
     Bank deposits:                        --           -- 11,554,754,721.43                     --            -- 12,131,569,238.87
     RMB                                   --           -- 9,879,590,764.20                      --            -- 10,797,711,400.19
     HKD                       563,828,766.21      0.8176      460,986,399.26 397,295,268.64             0.84164      334,379,589.89
     USD                       189,797,249.60      6.3757     1,210,090,324.28 152,908,866.07             6.5249      997,715,060.07
     Euro                           75,451.09      7.2197           544,734.23         78,241.56           8.025          627,888.52
     JPY                        43,429,022.00   0.055415          2,406,619.26                0.00     0.063126                  0.00
     MOP                         1,412,971.92      0.7936         1,121,334.52      1,370,869.68          0.8172         1,120,274.70
     GBP                             1,690.10      8.6064              14,545.68        1,690.10          8.8903           15,025.50
     Of bank deposits:
     deposit with
                                           --           --     174,250,489.57                    --            --     157,331,451.07
     nancial companies
     Other monetary
                                           --           --       12,784,212.07                   --            --      67,550,057.63
     funds:
     RMB                        67,298,631.20     0.81760        55,023,360.87      1,617,225.39         0.84164         1,361,121.58
     HKD                        13,562,944.28     6.37570        86,473,263.86     13,551,207.20          6.5249       88,420,271.86
     USD                                                         19,969,652.77
     Total                                                   11,729,230,390.98                                      12,289,098,613.19
     Of which: total
                                                              1,309,853,620.27                                       1,147,163,147.28
     overseas deposits


① Other monetary funds are mainly deposits for investments, deposits under guarantee of letter of guarantee, issuing letters of
   credit and foreign exchange forward contracts, etc.

② Structured deposits, time deposits in bank deposit, and restricted funds relating to issuing letters of credit and foreign exchange
   forward contracts, etc. in other monetary funds were deducted from cash and cash equivalents in the cash ow statement. Apart
   from these restricted funds, there is no other charge, pledge or lock up on the balance of cash at bank and on hand that may
   limit its use, is kept outside China and may have probable risks in its collection. Below are the details of the use of restricted
   monetary funds:


     Item                                                               31 December 2021                            31 December 2020
     Time deposit                                                                    0.00                             100,000,000.00
     Letter of Credit Margin                                                 1,788,607.74                                6,378,736.56
     Bank Acceptance Draft Margin                                            6,004,457.37                              57,075,915.14
     Other business margin                                                   3,949,531.92                                2,862,650.00
     Total                                                                  11,742,597.03                             166,317,301.70


                                                                                                                                  187
  2. Financial assets held for trading
     □ N/A
(1)Classication
                                                                                                           Unit: Yuan Currency: RMB
                                                                          Balance at the                            Balance at the
      Item
                                                                       End of the Period                   Beginning of the Period
      Financial asset measured at fair value through prot or loss        184,638,344.31                               28,328,748.72
      Of which:
      Debt instrument investments                                             940,162.94                                 909,752.05
      Equity instrument investments                                      176,321,853.05                               14,351,400.72
      Derivative nancial assets                                             7,376,328.32                              13,067,595.95
      Total                                                              184,638,344.31                               28,328,748.72


      Other descriptions:
      √ Applicable □ N/A

      ① The company's investments in equity instruments and debt instruments for financial assets held for trading at the End
         of the Period were listed for trading on Shenzhen Stock Exchange and Hong Kong Stock Exchange. The fair value was
         determined based on the closing price on the last trading day in the Reporting Period.
      ② Derivative financial assets represent foreign currency forward contracts, futures contracts and gains from unexpired
         contracts measured at fair value which were recognised as nancial assets as at the balance sheet date.

(2)No restrictive nancial asset measured at fair value through prot or loss was realised in the ending balance.

(3)No hedging instruments in the ending balance and no hedging transactions have occurred during the Period.


  3. Bills receivable
      √ Applicable □ N/A
                                                                                                           Unit: Yuan Currency: RMB
                                                                          Balance at the                            Balance at the
      Types of bills
                                                                       End of the Period                   Beginning of the Period
      Bank acceptance bills                                            1,977,767,022.02                             1,343,494,818.54
      bad debts                                                             -481,000.00                                  -481,000.00
      Total                                                            1,977,286,022.02                             1,343,013,818.54


 (1). Pledged bills receivables at the End of the Period
      √ Applicable □ N/A
                                                                                                           Unit: Yuan Currency: RMB
      Type                                                                                 Pledged amount at the End ofthe Period
      Bank acceptance bills                                                                                          870,153,979.75
      Total                                                                                                          870,153,979.75


      As at 31 December 2021, bills with carrying amount of RMB 870,153,979.75(31 December 2020: RMB 365,916,598.01)
      were pledged for bank acceptance bills.




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(2). Endorsed or discounted bills receivables not yet mature as of the balance sheet date at the End of the Period
     √ Applicable □ N/A
                                                                                                                                                    Unit: Yuan Currency: RMB
                                                                                                     Derecognised amount at                  Amount not derecognised at
     Type
                                                                                                       the End of the Period                      the End of the Period
     Bank acceptance bills not yet mature but already endorsed                                                  186,290,992.91                                                  0.00
     Bank acceptance bills not yet mature but already discounted                                                 67,908,033.05                                                  0.00
     Total                                                                                                      254,199,025.96                                                  0.00


     During the Year, the Company discounted RMB76,908,320 bank acceptance bills (Last Year: RMB208,990,920) to a bank. As
     the main risks (such as interest rate risks) and rewards related to these bank acceptance bills were transferred to the bank, the
     Company derecognised the undue bank acceptance bills that had been discounted. The discounted fee was RMB506,780 (Last
     Year: RMB2,036,920).

(3). Bills transferred into account receivables for non-performance by the issuer as at the End of the Period
     □ Applicable √ N/A

(4). Classication by method of provision for bad debts
     √ Applicable □ N/A
                                                                                                                                                    Unit: Yuan Currency: RMB
                                                   Balance at the End of the Period                                          Balance at the Beginning of the Period
                                         Gross amount           Provision for bad debt                               Gross amount            Provision for bad debt
                                                                             Expected                                                                     Expected
     Category
                                                 Percentage                     credit     Carrying value                    Percentage                         credit   Carrying value
                                      Amount                     Amount                                           Amount                      Amount
                                                        (%)                       loss                                               (%)                         loss
                                                                              rate (%)                                                                     rate (%)
     Provision for bad debt
                                   481,000.00           0.02 481,000.00        100.00               0.00        481,000.00          0.04 481,000.00         100.00                0.00
     on an individual basis
     Of which:
     Commercial acceptance
                                         0.00           0.00         0.00         0.00              0.00              0.00          0.00          0.00           0.00             0.00
     bills
     Bank acceptance bills         481,000.00           0.02 481,000.00        100.00               0.00        481,000.00          0.04 481,000.00         100.00                0.00
     Provision for bad debt
                              1,977,286,022.02       99.98           0.00         0.00 1,977,286,022.02 1,343,013,818.54           99.96          0.00           0.00 1,343,013,818.54
     on a collective basis
     Of which:
     Bank acceptance bills    1,977,286,022.02       99.98           0.00         0.00 1,977,286,022.02 1,343,013,818.54           99.96          0.00           0.00 1,343,013,818.54
     Total                    1,977,767,022.02      100.00 481,000.00             0.02 1,977,286,022.02 1,343,494,818.54         100.00 481,000.00               0.04 1,343,013,818.54


(5). Provision for bad debt on an individual basis :
     √ Applicable □ N/A
                                                                                                                                                    Unit: Yuan Currency: RMB
                                                                                      Balance at the End of the Period
     Name                                                                    Provision for bad              Expected credit
                                                  Gross amount                                                                             Reason for provision made
                                                                                          debt                loss rate (%)
     Henan Jiuzhoutong
                                                      431,000.00                      431,000.00                     100.00          Not expected to be recoverable
     Pharmaceutical Co., Ltd.
     Other customers                                    50,000.00                        50,000.00                   100.00          Not expected to be recoverable
     Total                                            481,000.00                      481,000.00                     100.00                                 /




                                                                                                                                                                                  189
      Descriptions of provision for bad debts made individually:
      □ Applicable √ N/A
      Provision for bad debt on a collective basis:
      □ Applicable √ N/A

      If the provision for bad debts is made in accordance with the general model of expected credit losses, please refer to other
      receivables disclosure:
      □ Applicable √ N/A

(6). Provision for bad debts
     √ Applicable □ N/A
                                                                                                           Unit: Yuan Currency: RMB
                                                                      Changes for the current period
                                 Balance at the Beginning                                                       Balance at the End
      Category                                                             Recovery or
                                             of the Period    Provision                     Removal/write-o          of the Period
                                                                              reversal
      Provision for bad debts                  481,000.00           0.00             0.00               0.00           481,000.00
      Total                                    481,000.00           0.00             0.00               0.00           481,000.00


      Signicant recovery or reversal of bad debt provision for the current period:
      √ N/A

(7). Bills receivable actually written o for the current period
     □ Applicable √ N/A

      Other descriptions:
      □ Applicable √ N/A


 4. Account receivables
(1). Disclosed by aging analysis
     √ Applicable □ N/A
                                                                                                           Unit: Yuan Currency: RMB
      Age                                                                                          Balance at the End of the Period
      Subtotal within 1 year:                                                                                    2,872,710,981.81
      1-2 years                                                                                                     18,541,236.06
      2-3 years                                                                                                     12,869,985.75
      3-4 years                                                                                                       7,835,031.26
      4-5 years                                                                                                       1,332,259.38
      Over 5 years                                                                                                  12,807,886.92
      Total                                                                                                      2,926,097,381.18


      According to the credit policy of the Company, the Company usually grants a credit period ranging from 30 to 90 days to its
      customers.




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(2). Disclosure by category based on methods of provision for bad debts
     √ Applicable □ N/A
                                                                                                                                                              Unit: Yuan Currency: RMB
                                                           Balance at the End of the Period                                             Balance at the Beginning of the Period
                                         Gross amount               Provision for bad debt                                  Gross amount                Provision for bad debt
     Category
                                                  Percentage                   Percentage       Carrying value                      Percentage                     Percentage       Carrying value
                                      Amount                        Amount                                               Amount                        Amount
                                                        (%)                           (%)                                                   (%)                            (%)
     Provision for bad debt
                                  9,709,854.02          0.33   5,513,168.82          56.78       4,196,685.20      10,426,275.67            0.41   6,229,590.47           59.75      4,196,685.20
     on an individual basis
     Of which:
     Due from domestic
                                  9,709,854.02          0.33   5,513,168.82          56.78       4,196,685.20      10,312,742.41            0.41   6,116,057.21           59.31      4,196,685.20
     customers
     Due from overseas
                                          0.00          0.00            0.00          0.00                0.00        113,533.26            0.00     113,533.26          100.00               0.00
     customers
     Provision for bad debt
                              2,916,387,527.16        99.67 66,928,660.82             2.29    2,849,458,866.34   2,514,820,193.56          99.59 71,610,656.24             2.85   2,443,209,537.32
     on a collective basis
     Of which:
     Due from domestic
                              2,333,938,533.50        79.76 58,705,544.56             2.52    2,275,232,988.94   2,028,481,823.13          80.33 64,858,199.12             3.20   1,963,623,624.01
     customers
     Due from overseas
                               582,448,993.66         19.91    8,223,116.26           1.41     574,225,877.40     486,338,370.43           19.26   6,752,457.12            1.39    479,585,913.31
     customers
     Total                    2,926,097,381.18       100.00 72,441,829.64             2.48    2,853,655,551.54   2,525,246,469.23           100 77,840,246.71              3.08   2,447,406,222.52


    Provision for bad debt on an individual basis:
    √ Applicable □ N/A
                                                                                                                                                              Unit: Yuan Currency: RMB
                                                                                         Balance at the End of the Period
     Description
                                             Gross amount                 Provision for bad debt                 Percentage (%)                    Reason for provision made
     Payment for goods                           9,709,854.02                            5,513,168.82                          56.78           Not expected to be recoverable
     Total                                       9,709,854.02                            5,513,168.82                          56.78                                 /


    Descriptions of provision for bad debts made individually:
    □ Applicable √ N/A

    Provision for bad debt on a collective basis:
    √ Applicable □ N/A

    Item: Due from domestic customers
                                                                                                                                                              Unit: Yuan Currency: RMB
                                                                                                         Balance at the End of the Period
     Name
                                                                     Account receivables                         Provision for bad debt                                     Percentage (%)
     Within 1 year:                                                      2,290,261,988.15                                    32,953,674.70                                                 1.44
     1-2 years(including 2 years)                                            18,541,236.06                                   2,450,973.15                                              13.22
     2-3 years(including 3years)                                              4,476,615.34                                   2,960,042.15                                              66.12
     3-4years(including 4 years)                                              7,550,258.06                                  7,277,583.42                                               96.39
     4-5 years(including 5 years)                                             1,271,992.78                                  1,226,828.03                                               96.45
     Over 5 years                                                              11,836,443.11                                 11,836,443.11                                              100.00
     Total                                                               2,333,938,533.50                                    58,705,544.56                                                 2.52




                                                                                                                                                                                             191
      Standards of provision for bad debts on a collective basis and descriptions thereof:
      □ Applicable √ N/A

      Item: Due from overseas customers
                                                                                                               Unit: Yuan Currency: RMB
                                                                           Balance at the End of the Period
      Name
                                                   Account receivables          Provision for bad debt                  Percentage (%)
      Within 1 year:                                   582,448,993.66                    8,223,116.26                             1.41
      1-2 years(including 2 years)                                0.00                          0.00                            0.00
      2-3 years(including 3years)                                 0.00                          0.00                            0.00
      3-4years(including 4 years)                                 0.00                          0.00                            0.00
      4-5 years(including 5 years)                                0.00                          0.00                           0.00
      Over 5 years                                                  0.00                          0.00                           0.00
      Total                                            582,448,993.66                    8,223,116.26                            1.41


      Standards of provision for bad debts on a collective basis and descriptions thereof:
      □ Applicable √ N/A

      If the provision for bad debts is made in accordance with the general model of expected credit losses, please refer to other
      receivables disclosure:
      □ Applicable √ N/A

(3). Provision for bad debts
     √ Applicable □ N/A
                                                                                                               Unit: Yuan Currency: RMB
                                  Balance at the                       Changes for the current period                       Balance at
      Category                     Beginning of                   Recovery or                                   Other       the End of
                                                        Provision                    Removal/write-o
                                     the Period                      reversal                                 changes       the Period
      Provision for bad debts     77,840,246.71      9,189,454.14            0.00       14,572,969.66    -14,901.55     72,441,829.64
      Total                       77,840,246.71      9,189,454.14            0.00       14,572,969.66    -14,901.55     72,441,829.64


      As of 31 December 2020 and of 31 December 2021, the Company had no accounts receivable that were past due but had not
      be impaired.

      Signicant recovery or reversal of bad debt provision for the current period:
      □ Applicable √ N/A

(4). Actual write-o of account receivables for the Period
     √ Applicable □ N/A
                                                                                                               Unit: Yuan Currency: RMB
      Item                                                                                                         Amount written-o
      Accounts receivable actually written o                                                                            14,572,969.66


      Signicant accounts receivable that are written o:
      □ Applicable √ N/A

      Descriptions of write-o of accounts receivable:
      □ Applicable √ N/A




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(5). Total amount of account receivables of top ve balances of accounts receivables by debtors at the End of the Period
     √ Applicable □ N/A
                                                                                                            Unit: Yuan Currency: RMB
                                                        A/R                Percentage% as total A/R             Bad Debt Provision
     Name of Debtors
                                              Ending Balance                      (Ending Balance)               (Ending Balance)
     Debtor 1                                 101,210,658.25                                    3.46                    694,990.42
     Debtor 2                                  70,072,167.75                                    2.39                    679,833.87
     Debtor 3                                  60,585,663.88                                    2.07                    590,107.52
     Debtor 4                                  56,782,566.75                                    1.94                    554,141.08
     Debtor 5                                  50,897,405.05                                    1.74                    519,263.27
     Total                                    339,548,461.68                                   11.60                  3,038,336.16


    Other descriptions:
    The total amount of the top ve balances of accounts receivables by debtors at the End of the Year was RMB 339,548,461.68
    for the Period, representing 11.60% of the total balances of accounts receivables at the End of the Year, and the corresponding
    aggregate amount of the balances of provision for bad debt at the End of the Year was RMB 3,038,336.16.

(6). Derecognised account receivables due to the transfer of nancial assets.
     □ Applicable √ N/A

(7). Assets or liabilities formed by its continuous involvement of transferring account receivables
     □ Applicable √ N/A

     Other descriptions:
     □ Applicable √ N/A


5. Prepayments
(1) Disclosure of prepayments by aging analysis
    √ Applicable □ N/A
                                                                                                            Unit: Yuan Currency: RMB
                                                Balance at the End of the Period             Balance at the Beginning of the Period
     Age
                                               Amount            Percentage (%)                   Amount            Percentage (%)
     Within 1 year                     354,340,559.20                      95.97           199,646,272.88                    95.11
     1-2 years                            8,031,100.50                       2.17            8,545,039.74                     4.07
     2-3 years                            6,323,201.42                       1.71              552,633.55                     0.26
     Over 3 years                           537,685.17                       0.15            1,182,094.40                     0.56
     Total                             369,232,546.29                     100.00           209,926,040.57                   100.00


(2) Prepayments with ve largest amounts by receivers of prepayments at the End of the Period
    √ Applicable □ N/A


                                                                                                 Percentage% as of Ending Balance
     Name of Receivers                          Ending Balance of Prepayments
                                                                                                              of Toal Prepayments
     Receiver 1                                                   41,409,303.20                                              11.21
     Receiver 2                                                   15,523,899.11                                               4.20
     Receiver 3                                                   13,160,000.00                                               3.56
     Receiver 4                                                   12,199,251.14                                               3.30
     Receiver 5                                                   11,105,927.86                                               3.01
     Total                                                        93,398,381.31                                              25.30




                                                                                                                                193
      Other descriptions:
      The aggregate amount of prepayments paid to the five largest receivers of prepayments at the End of the Period was
      RMB93,398,381.31 for the Period, representing 25.30% of the total balance of prepayments at the End of the Period.

      Other descriptions:
      □ Applicable √ N/A


 6. Other receivables
      Line items
      √ Applicable □ N/A
                                                                                                  Unit: Yuan Currency: RMB
      Item                                  Balance at the End of the Period        Balance at the Beginning of the Period
      Interest receivable                                       365,873.64                                           0.00
      Other receivables                                      87,687,951.48                                177,240,162.81
      Total                                                  88,053,825.12                                177,240,162.81


      Other descriptions:
      □ Applicable √ N/A

      Interest receivable
      √ Applicable □ N/A
                                                                                                  Unit: Yuan Currency: RMB
      Project                               Balance at the End of the Period        Balance at the Beginning of the Period
      Term interests                                            365,873.64                                           0.00
      Total                                                     365,873.64                                           0.00


     Other receivables
 (1) Disclosure by aging analysis
     √ Applicable □ N/A
                                                                                                  Unit: Yuan Currency: RMB
      Age                                                                                 Balance at the End of the Period
      Subtotal within 1 year                                                                               53,953,012.32
      1-2 years                                                                                            33,803,432.35
      2-3 years                                                                                              1,821,553.83
      3-4 years                                                                                              2,532,015.23
      4-5 years                                                                                               807,025.60
      Over 5 years                                                                                          50,248,098.81
      Provision for bad debt                                                                               -55,477,186.66
      Total                                                                                                87,687,951.48




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(2) Disclosure by nature of amounts
    √ Applicable □ N/A
                                                                                                                  Unit: Yuan Currency: RMB
                                                                          Balance at the End                    Balance at the Beginning
     Nature
                                                                               of the Period                                of the Period
     Deposits under guarantee, deposits and lease expenses                     11,003,281.04                               10,427,225.66
     Reserved fund and advances                                                17,870,245.40                               22,442,315.38
     Related party balances                                                    20,323,903.96                               34,057,672.41
     External entities balances                                                22,421,780.76                               20,635,951.11
     Tax refund on exports                                                     17,708,111.60                               23,764,211.44
     Treasury bonds and margin                                                 17,968,386.04                               18,982,036.71
     Capital reduction                                                         24,078,925.22                               92,347,581.27
     Amounts of exercised options                                               8,463,240.98                                   9,169,356.40
     Others                                                                     3,327,263.14                                   2,610,860.99
     Total                                                                    143,165,138.14                              234,437,211.37


(3) Provision for bad debt
    √ Applicable □ N/A
    At the End of the Period, the provision for bad debt in Step 1 was as follows:


                                                                          Expected credit      Provision
     Category                                         Gross amount      loss rate over the       for bad      Carrying value        Reason
                                                                      next 12 months (%)            debt
     Provision for bad debt on an individual basis    32,542,166.20                    0.00         0.00      32,542,166.20
     Amounts of exercised options                      8,463,240.98                    0.00         0.00       8,463,240.98 Recoverable
     Capital reduction                                24,078,925.22                    0.00         0.00      24,078,925.22 Recoverable
     Provision for bad debt on a collective basis              0.00                    0.00         0.00               0.00
     Total                                            32,542,166.20                    0.00         0.00      32,542,166.20


    At the End of the Period, the provision for bad debt in Step 2 was as follows:


                                                                        Expected credit
                                                              Gross                           Provision for           Carrying
     Category                                                         loss rate over the                                            Reason
                                                             amount                               bad debt               value
                                                                           lifetime (%)
     Provision for bad debt on an individual basis             0.00                   0.00            0.00                0.00
     Provision for bad debt on a collective basis    63,594,020.80                   13.28    8,448,235.52      55,145,785.28
     Export tax refund receivable                    17,708,111.60                    1.12     198,927.69       17,509,183.91
     Deposits under guarantee, deposits and lease
                                                     11,003,281.04                   26.33    2,897,272.69       8,106,008.35
     expenses receivable
     Other receivables                               34,882,628.16                   15.34    5,352,035.14      29,530,593.02
     Total                                           63,594,020.80                   13.28    8,448,235.52      55,145,785.28




                                                                                                                                        195
      At the End of the Period, the provision for bad debt in Step 3 was as follows:


                                                                          Expected credit
                                                               Gross                            Provision for      Carrying
      Category                                                          loss rate over the                                            Reason
                                                              amount                                bad debt          value
                                                                             lifetime (%)
      Provision for bad debt on an individual basis    47,028,951.14               100.00 47,028,951.14                0.00
                                                                                                                                 Not expected
      Other receivables                                47,028,951.14               100.00 47,028,951.14                0.00             to be
                                                                                                                                  recoverable
      Provision for bad debt on a collective basis               0.00                   0.00             0.00          0.00
      Total                                            47,028,951.14               100.00 47,028,951.14                0.00


      Provision for bad debt as at 31 December 2020
      At the End of 2020, the provision for bad debt in Step 1 was as follows:


                                                                            Expected credit      Provision
      Category                                          Gross amount      loss rate over the       for bad      Carrying value        Reason
                                                                        next 12 months (%)            debt
      Provision for bad debt on an individual basis   101,516,937.67                     0.00         0.00 101,516,937.67
      Amounts of exercised options                      9,169,356.40                     0.00         0.00       9,169,356.40 Recoverable
      Capital reduction                                92,347,581.27                     0.00         0.00      92,347,581.27 Recoverable
      Provision for bad debt on a collective basis               0.00                    0.00         0.00               0.00
      Total                                           101,516,937.67                     0.00         0.00 101,516,937.67


      At the End of 2020, the provision for bad debt in Step 2 was as follows:


                                                                          Expected credit
                                                               Gross                            Provision for           Carrying
      Category                                                          loss rate over the                                            Reason
                                                              amount                                bad debt               value
                                                                             lifetime (%)
      Provision for bad debt on an individual basis              0.00                   0.00            0.00                  0.00
      Provision for bad debt on a collective basis     84,877,671.89                   10.79    9,154,446.75      75,723,225.14
      Export tax refund receivable                     23,764,211.44                    1.05     250,463.32       23,513,748.12
      Deposits under guarantee, deposits and lease
                                                       10,427,225.66                   25.18    2,625,854.42       7,801,371.24
      expenses receivable
      Other receivables                                50,686,234.79                   12.39    6,278,129.01      44,408,105.78
      Total                                            84,877,671.89                   10.79    9,154,446.75      75,723,225.14


      At the End of 2020, the provision for bad debt in Step 3 was as follows:


                                                                          Expected credit
                                                               Gross                            Provision for      Carrying
      Category                                                          loss rate over the                                            Reason
                                                              amount                                bad debt          value
                                                                             lifetime (%)
      Provision for bad debt on an individual basis    48,042,601.81               100.00 48,042,601.81                0.00
                                                                                                                                 Not expected
      Other receivables                                48,042,601.81               100.00 48,042,601.81                0.00             to be
                                                                                                                                  recoverable
      Provision for bad debt on a collective basis               0.00                   0.00             0.00          0.00
      Total                                            48,042,601.81               100.00 48,042,601.81                0.00




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(4) Provision for bad debts made, recovered or reversed during the Period
                                                                                                           Unit: Yuan Currency: RMB
                                                    Step 1                       Step 2                   Step 3
                                          Expected credit    Expected credit loss over      Expected credit loss
     Provision for bad debt                                                                                                   Total
                                        loss over the next       the lifetime (without    over the lifetime (with
                                               12 months        impairment of credit)      impairment of credit)
     Balance at 1 January 2021                        0.00              9,154,446.75              48,042,601.81       57,197,048.56
     Movements of balance at 1
     January 2021
     – Transferred to Step 2                         0.00                         0.00                     0.00               0.00
     – Transferred to Step 3                         0.00                  -488,887.77              488,887.77                0.00
     – Reversed to Step 2                            0.00                         0.00                     0.00               0.00
     – Reversed to Step 1                            0.00                         0.00                     0.00               0.00
     Provision made for the Period                    0.00                  -151,691.27                     0.00        -151,691.27
     Reversals during the Period                      0.00                                         1,013,650.67        1,013,650.67
     Settlement during the Period                     0.00                         0.00                     0.00               0.00
     Write-o during the Period                        0.00                         0.00              488,887.77          488,887.77
     Other changes                                    0.00                   -65,632.19                     0.00         -65,632.19
     Balance at 31 December 2021                      0.00              8,448,235.52              47,028,951.14       55,477,186.66


    Descriptions of the significant changes in the gross carrying amount of other receivables for which the changes in loss
    allowance occur for the current period
    □ Applicable √ N/A

    Provision for bad debts in the current period and the basis for assessing whether the credit risk of financial instruments has
    increased signicantly:
    □ Applicable √ N/A

(5) Other receivables actually written o during the Period
    √ Applicable □ N/A
                                                                                                           Unit: Yuan Currency: RMB
     Item                                                                                                      Amount written o
     Other receivables actually written o                                                                                488,887.77


    Signicant other receivables that are written o:
    □ Applicable √ N/A

    Descriptions of write-o of other receivables:
    □ Applicable √ N/A




                                                                                                                                197
 (6) Aggregate amount of other receivables due from the top ve parties with the largest amounts at the End of the Period
     √ Applicable □ N/A
                                                                                                                   Unit: Yuan Currency: RMB
                                                                                                  Percentage in the
                                                                Balance of other                   total balance of Provision for bad
      Name of entity                    Nature of amount       receivables at the             Age other receivables  debts at the end
                                                               End of the Period                      at the End of     of the Period
                                                                                                    the Period (%)
      Shanghai Yunfeng Xinchuang
                                 Capital reduction                 24,078,925.22         1-2 years               16.82                  0.00
      Equity Investment Center
      Shenzhen Jiekang Health           Related party
                                                                   18,577,246.63      Over 5 years               12.98       18,577,246.63
      Care Co., Ltd.                    balances
                                        Treasury bonds
      Hua Xia Securities Co., Ltd.                                 17,968,386.04      Over 5 years               12.55       17,968,386.04
                                        and margin
      Tax refunds on exports            Export tax refund          17,708,111.60 Within 1 year                   12.37          198,927.69
      China Securities Depository
                                        Amount of
      and Clearing Corporation                                      8,463,240.98 Within 1 year                     5.91                 0.00
                                        exercised options
      Limited (Shenzhen Branch)
      Total                             /                          86,795,910.47                  /              60.63       36,744,560.36


 (7) Other receivables due to the transfer of nancial assets
     □ Applicable √ N/A

 (8) Assets or liabilities formed by its continuous involvement of transferring other receivables:
     □ Applicable √ N/A

      Other descriptions
      □ Applicable √ N/A

 7. Inventories
(1). Classication of inventories
     √ Applicable □ N/A
                                                                                                                   Unit: Yuan Currency: RMB
                                          Balance at the End of the Period                      Balance at the Beginning of the Period
                                                  Provision for                                             Provision for
      Item
                                Gross amount        diminution      Carrying amount      Gross amount         diminution     Carrying amount
                                                        in value                                                 in value
      Raw materials            553,234,567.88 16,068,254.74          537,166,313.14     449,307,601.96 24,992,444.56          424,315,157.40
      Packaging materials      125,197,237.91     7,099,883.19       118,097,354.72      68,812,746.78      7,353,583.54        61,459,163.24
      Goods in process
      and Proprietary          538,151,968.97     2,891,675.04       535,260,293.93     372,253,640.56     2,679,118.64      369,574,521.92
      semi-nished goods
      Low-value
                                61,806,078.47       217,760.90        61,588,317.57      32,476,319.46       382,146.01        32,094,173.45
      consumables
      Finished goods and
                               834,035,538.26    30,182,179.43       803,853,358.83     947,677,545.58    33,908,986.43      913,768,559.15
      stock goods
      Sub-contracting
                                 2,251,074.26               0.00       2,251,074.26       1,863,102.15              0.00        1,863,102.15
      materials
      Consumable
                                12,342,303.96               0.00      12,342,303.96      11,511,335.81              0.00       11,511,335.81
      biological assets
      Goods in transit          8,385,371.27              0.00         8,385,371.27    16,922,999.15               0.00        16,922,999.15
      Total                 2,135,404,140.98     56,459,753.30     2,078,944,387.68 1,900,825,291.45      69,316,279.18     1,831,509,012.27


198
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(2). Provision for diminution in value of inventories and provision for diminution in value of contract performance costs
     √ Applicable □ N/A
                                                                                                              Unit: Yuan Currency: RMB
                                          Balance at the Increase during the Period     Decrease during the Period       Balance at the
     Item                                    Beginning                                        Reversed or                   End of the
                                                               Provision      Other                            Other
                                             of the Year                                       written o                        Period
     Raw materials                        24,992,444.56     23,244,030.42        0.00   32,168,220.24           0.00     16,068,254.74
     Packaging materials                   7,353,583.54      2,070,617.16        0.00      2,324,317.51         0.00      7,099,883.19
     Goods in process and Proprietary
                                           2,679,118.64      3,587,621.55        0.00      3,375,065.15         0.00      2,891,675.04
     semi-nished goods
     Low-value consumables                     382,146.01       30,790.83        0.00         195,175.94        0.00        217,760.90
     Finished goods and stock goods       33,908,986.43     33,506,690.02        0.00   37,233,497.02           0.00     30,182,179.43
     Total                                69,316,279.18     62,439,749.98        0.00   75,296,275.86           0.00     56,459,753.30


    Provision for diminution in value of inventories (Continued)


                                                                                                    Reason for reversal or write
                                                                                                    o provision for diminution in
                                         Basis for determination of net realisable value/
     Item                                                                                           value of inventories/impairment
                                         remaining consideration and the cost to be incurred
                                                                                                    provision for contract performance
                                                                                                    cost during the Period
                                         The estimated selling price less the estimated costs       Processing, sale of nished goods
     Raw materials
                                         of completion, selling expenses and related taxes          and discard
                                         The estimated selling price less the estimated costs       Processing, sale of nished goods
     Packaging materials
                                         of completion, selling expenses and related taxes          and discard
     Goods in process and Proprietary The estimated selling price less the estimated costs          Processing of nished goods and
     semi-nished goods                of completion, selling expenses and related taxes             discard
     Low-value consumables               The estimated selling price less the related taxes         Discard
                                         The estimated selling price less the estimated selling
     Finished goods and stock goods                                                                 Sale and discard
                                         expenses and related taxes


(3). Descriptions at the End of the Period of inventories including capitalised amount of borrowing costs
     □ Applicable √ N/A

    Other descriptions:
    □ Applicable √ N/A


8. Non-current assets due within one year
    √ Applicable □ N/A
                                                                                                              Unit: Yuan Currency: RMB
     Item                                               Balance at the End of the Period        Balance at the Beginning of the Period
     Long-term receivables due within one year                               317,381.23                                  11,414,376.07
     Interest receivable due within one year                                        0.00                                  8,520,000.00
     Total                                                                   317,381.23                                  19,934,376.07


    Signicant debt investments and other debt investments at the end of the period:
    □ Applicable √ N/A




                                                                                                                                   199
 9. Other current assets
      √ Applicable □ N/A
                                                                                                               Unit: Yuan Currency: RMB
      Item                                              Balance at the End of the Period        Balance at the Beginning of the Period
      Input VAT pending deduction/attestation                                53,179,328.86                              49,003,571.19
      Advance payment of income tax                                          30,667,849.83                               9,094,478.01
      Others                                                                   139,035.68                                         0.00
      Total                                                                  83,986,214.37                              58,098,049.20


10. Long-term receivables
 (1) Descriptions of long-term receivables
     √ Applicable □ N/A
                                                                                                               Unit: Yuan Currency: RMB
                                          Balance at the End of the Period           Balance at the Beginning of the Period
                                                                                                                              Range of
                                                  Provision                                      Provision
      Item                               Gross                   Carrying              Gross                      Carrying    discount
                                                        for                                            for
                                        amount                      value             amount                          value        rate
                                                  bad debts                                      bad debts
      Receivables from equity
                                           0.00        0.00          0.00      10,967,767.26         0.00   10,967,767.26       5.00%
      transferred by installments
      Finance lease payment         584,285.36         0.00   584,285.36         1,030,893.17        0.00     1,030,893.17      4.75%
      Long-term receivables
                                    -317,381.23        0.00 -317,381.23        -11,414,376.07        0.00 -11,414,376.07
      due within one year
      Total                         266,904.13         0.00   266,904.13          584,284.36         0.00      584,284.36


 (2) Provision for bad debts
     □ Applicable √ N/A

      The provision amount of bad debt reservesin the current period and the basis for assessing whether the credit risk of nancial
      instruments has increased signicantly:
      □ Applicable √ N/A

 (3) Long-term receivables derecognised out of transfer of nancial assets.
     □ Applicable √ N/A

 (4) Assets or liabilities formed by its continuous involvement of transferring long-term receivables.
     □ Applicable √ N/A

      Other descriptions:
      □ Applicable √ N/A




200
                                                                                                                                                                                        Annual Report
                                                                                                                                                                                                2021


11. Long-term equity investments
    √ Applicable □ N/A
                                                                                                                                                                               Unit: Yuan Currency: RMB
                                                                                                      Change during the Period                                                                              Balance of
                                       Balance at                                      Investment      Adjustment                        Cash dividend                                                    provision for
                                                                                                                                 Other                     Provision                    Balance at the
    Investee                        the Beginning         additional   Decreased    prot and loss          in other                           or prot                                                    impairment at
                                                                                                                             equity                              for       Others    End of the Period
                                     of the Period       investment    investment        under the   comprehensive                         distribution                                                  the End of the
                                                                                                                            changes                       impairment
                                                                                    equity method           income                            declared                                                          Period
    I. Subsidiaries
    Zhongshan Renhe Health
                                     6,337,823.35              0.00          0.00            0.00             0.00                0.00            0.00          0.00         0.00        6,337,823.35    6,337,823.35
    Products Co., Ltd.
    Guangzhou Hiyeah Industry
                                     1,949,893.45              0.00          0.00            0.00             0.00                0.00            0.00          0.00         0.00        1,949,893.45    1,949,893.45
    Co., Ltd.
    Subtotal                         8,287,716.80              0.00          0.00            0.00             0.00                0.00            0.00          0.00         0.00        8,287,716.80    8,287,716.80
    II. Associates
    Livzon Medical Electronic
                                     1,200,000.00              0.00          0.00            0.00             0.00                0.00            0.00          0.00         0.00        1,200,000.00    1,200,000.00
    Equipment (Plant) Co., Ltd.
    Guangdong Blue Treasure
                                    72,271,987.53              0.00          0.00   17,232,604.65             0.00                0.00 11,475,000.00            0.00         0.00       78,029,592.18             0.00
    Pharmaceutical Co. Ltd.
    Shenzhen City Youbao
                                     1,080,543.04              0.00          0.00      141,855.85             0.00                0.00            0.00          0.00         0.00        1,222,398.89             0.00
    Technology Co., Ltd.
    AbCyte Therapeutics Inc.        16,183,551.42              0.00          0.00    -1,028,841.46            0.00                0.00            0.00          0.00         0.00       15,154,709.96             0.00
    L&L Biopharma, Co. Ltd.         14,024,119.09              0.00          0.00    -1,650,109.20            0.00     2,658,626.68               0.00          0.00   -145,798.11      14,886,838.46             0.00
    Zhuhai Sanmed Biotech Inc.*     31,649,784.72              0.00          0.00   -18,179,141.47      -30,268.27 69,715,182.18                  0.00          0.00         0.00       83,155,557.16             0.00
    Aetio Biotheraphy, Inc.         17,647,744.60              0.00          0.00    -1,619,256.12            0.00                0.00            0.00          0.00         0.00       16,028,488.48             0.00
    Jiangsu Atom Bioscience and
                                    70,260,600.00              0.00          0.00    -2,351,992.02            0.00                0.00            0.00          0.00         0.00       67,908,607.98             0.00
    Pharmaceutical Co., Ltd.
    Tianjin Tongrentang Group
                                             0.00    724,000,000.00          0.00   52,620,894.45    14,820,196.44       148,673.03 40,040,000.00               0.00         0.00     751,549,763.92              0.00
    Co., Ltd.*
    Innite Intelligence
                                             0.00     20,000,000.00          0.00    -1,199,311.93            0.00     1,137,221.57               0.00          0.00         0.00       19,937,909.64             0.00
    Pharmaceutical Co. Ltd.
    Jiaozuo Jinguan Jiahua
                                   316,556,367.05              0.00          0.00   -31,936,458.04            0.00                0.00            0.00          0.00         0.00     284,619,909.01              0.00
    Electric Power Co., Ltd.
    Ningbo Ningrong Biomedical
                                    28,301,318.36              0.00          0.00     -837,219.65             0.00                0.00            0.00          0.00         0.00       27,464,098.71             0.00
    Co., Ltd.
    Feellife Health Inc.            11,964,576.16              0.00          0.00      769,797.06             0.00                0.00            0.00          0.00         0.00       12,734,373.22             0.00
     Novastage Pharmaceuticals
                                    19,561,050.64              0.00          0.00    -1,480,167.43            0.00                0.00            0.00          0.00         0.00       18,080,883.21             0.00
    (Shenzhen), Ltd.
    Jiangsu Baining Yingchuang
                                    28,777,957.12              0.00          0.00     -201,633.10             0.00                0.00            0.00          0.00         0.00       28,576,324.02             0.00
    Medical Technology Co., Ltd.
    Subtotal                       629,479,599.73    744,000,000.00          0.00   10,281,021.59    14,789,928.17 73,659,703.46 51,515,000.00                  0.00   -145,798.11   1,420,549,454.84    1,200,000.00
    Total                          637,767,316.53    744,000,000.00          0.00   10,281,021.59    14,789,928.17 73,659,703.46 51,515,000.00                  0.00   -145,798.11   1,428,837,171.64    9,487,716.80



    Note1: Other equity changes of L&L Biopharma Co., Ltd. ( 上海健信生物医药科技有限公司 ) and Zhuhai Sanmed Biotech
           Inc.( 珠 海 圣 美 生 物 诊 断 技 术 有 限 公 司 ) are non-proportional capital increase, and Livzon Group's share of such
           changes was calculated in proportion to its equity interest.




                                                                                                                                                                                                                 201
      Note2: In April 2021, Livzon Group entered into the Share Transfer Agreement in relation to Tianjin Tongrentang Group Co.,
             Ltd. with Tianjin Tasly Healthcare Industry Investment Partnership (Limited Partnership) ( 天津天士力健康产业投资
             合 伙 企 业( 有 限 合 伙 )) (“Tianjin Tasly”), Livzon Group shall acquire 44,000,000 shares of Tianjin Tongrentang
             Group Co., Ltd. ( 天 津 同 仁 堂 集 团 股 份 有 限 公 司 ) (“Tianjin Tongrentang”) held by Tianjin Tasly, representing
             40.00% of the total number of shares of Tianjin Tongrentang at the consideration of RMB724 million. On 27 April
             2021, Livzon Group obtained the Confirmation Letter for Securities Transfer and Registration from China Securities
             Depository and Clearing Co., Ltd. conrming Livzon Group had acquired 40.00% equity of Tianjin Tongrentang.

      Note3: In February 2021, Zhuhai Livzon Pharmaceutical Equity Investment Management Co., Ltd. ( 珠海市丽珠医药股权投
             资 管 理 有 限 公 司 ), the subsidiary of Livzon Group (“Equity Investment Company”) entered into the Shareholder
             Agreement with Beijing Innite Intelligence Pharmaceutical Technology Co., Ltd. ( 北 京 英 飞 智 药 科 技 有 限 公
             司 ) (“Infinite Intelligence Pharma”), Equity Investment Company contribute a total of RMB20,000,000 to hold
             11.7647% equity of Infinite Intelligence Pharma. According to the Shareholder Agreement and the provisions of the
             articles of association, Equity Investment Company shall appoint one director to Infinite Intelligence Pharma. Since
             the Equity Investment Company can have a significant impact on Infinite Intelligence Pharma, the investment in
             Infinite Intelligence Pharma will be accounted as long-term equity investment; Other changes in equity shall be non-
             proportional capital increase which is calculated according to the shareholding ratio of the Equity Investment Company.
             After the capital increase, the shareholding ratio of the Equity Investment Company shall become 10.989%.


12. Other equity instrument investments
 (1) Descriptions of other equity investment
     √ Applicable □ N/A
                                                                                                            Unit: Yuan Currency: RMB
                                                                            Balance at the End             Balance at the Beginning
      Item
                                                                                 of the Period                         of the Period
      China Galaxy Securities Co., Ltd.                                        212,384,666.97                       237,438,086.13
      Shanghai Yunfeng Xinchuang Equity Investment Center                       94,040,236.88                       112,254,757.06
      Shanghai JingYi Investment Center                                         66,175,062.50                        67,661,520.76
      Qianhai Equity Investment Fund                                           264,930,500.00                       253,987,145.00
      Apricot Forest, Inc                                                      137,711,800.01                       149,384,486.40
      PANTHEON D ,L.P.                                                            3,715,566.69                       12,680,875.63
      Zhuhai China Resources Bank Co., Ltd.                                    164,395,200.00                       170,772,300.00
      GLOBAL HEALTH SCIENCE                                                    235,133,216.46                       246,837,324.35
      SCC VENTURE VI 2018-B,L.P.                                                  6,615,626.07                       13,823,660.49
      SCC VENTURE VII 2018-C,L.P.                                                         0.00                      176,752,020.58
      Nextech V Oncology S.C.S., SICAV-SIF                                      30,667,263.04                        29,583,312.39
      Yizun Biopharmaceutics (Shanghai) Co., Ltd.                               59,999,953.41                        30,000,000.00
      ELICIO THERAPEUTICS, INC.                                                 31,878,510.16                        32,624,491.32
      CARIAMA THER APEUTICS INC.                                                31,876,936.63                        32,622,880.98
      Beijing Luzhu Biotechnology Co., Ltd.                                     41,944,015.67                                  0.00
      Shanghai Keentai Biotechnology Co., Ltd.                                  12,000,000.00                                  0.00
      Others                                                                    15,413,822.93                          9,968,802.04
      Total                                                                  1,408,882,377.42                     1,576,391,663.13




202
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                                                                                                                          2021


(2) Descriptions of investments in non-trading equity instruments
    √ Applicable □ N/A
                                                                                                             Unit: Yuan Currency: RMB
                                                                                                   Amount Reason for the
                                                        Dividend                                transferred   designation
                                                          income    Cumulative Cumulative       from other   as fair value Reason
     Item
                                                      recognised        gains      losses comprehensive through other for transfer
                                                   for the Period                                income to comprehensive
                                                                                          retained earning        income
     China Galaxy Securities Co., Ltd.              4,175,569.86          0.00       0.00             0.00    non-trading
     Shanghai Yunfeng Xinchuang Equity
                                                            0.00          0.00       0.00             0.00    non-trading
     Investment Center
     Shanghai JingYi Investment Center                      0.00          0.00       0.00             0.00    non-trading
     Qianhai Equity Investment Fund                12,224,832.07          0.00       0.00             0.00    non-trading
     Apricot Forest, Inc                                    0.00          0.00       0.00             0.00    non-trading
     PANTHEON D ,L.P.                                       0.00          0.00       0.00             0.00    non-trading
     Zhuhai China Resources Bank Co., Ltd.                  0.00          0.00       0.00             0.00    non-trading
     GLOBAL HEALTH SCIENCE                                  0.00          0.00       0.00             0.00    non-trading
                                                                                                                            Corporate
                                                                                                                           lapsed and
     SCC VENTURE VI 2018-B,L.P.                             0.00          0.00       0.00   137,631,513.65    non-trading
                                                                                                                          investment
                                                                                                                          withdrawn
     SCC VENTURE VII 2018-C,L.P.                            0.00          0.00       0.00             0.00    non-trading
     Nextech V Oncology S.C.S., SICAV-SIF          21,298,939.65          0.00       0.00             0.00    non-trading
     Yizun Biopharmaceutics (Shanghai) Co., Ltd.            0.00          0.00       0.00             0.00    non-trading
     ELICIO THERAPEUTICS, INC.                              0.00          0.00       0.00             0.00    non-trading
     CARIAMA THER APEUTICS INC.                             0.00          0.00       0.00             0.00    non-trading
     Beijing Luzhu Biotechnology Co., Ltd.                  0.00          0.00       0.00             0.00    non-trading
     Shanghai Keentai Biotechnology Co., Ltd.               0.00          0.00       0.00             0.00    non-trading
     Others                                           25,000.00           0.00       0.00    34,295,275.82    non-trading   Disposal
     Total                                         37,724,341.58          0.00       0.00   171,926,789.47


    Other descriptions:
    □ Applicable √ N/A




                                                                                                                                 203
13. Investment property
     Measurementof investment properties
(1). Investment properties measured at cost
                                                                                                         Unit: Yuan Currency: RMB
      Item                                                                  Plant and buildings                            Total
      I. Original book value:
      1. Balance at the Beginning of the Period                                  61,914,754.28                    61,914,754.28
      2. Additions for the Period                                                         0.00                              0.00
      3. Decrease for the Period                                                          0.00                              0.00
      4. Balance at the End of the Period                                        61,914,754.28                    61,914,754.28
      II. Accumulated depreciation and amortisation
      1. Balance at the Beginning of the Period                                  55,723,278.85                    55,723,278.85
      2. Additions for the Period                                                         0.00                              0.00
      (1) Provision or amortisation                                                       0.00                              0.00
      3. Decrease for the Period                                                          0.00                              0.00
      (1) Disposal                                                                        0.00                              0.00
      4. Balance at the End of the Period                                        55,723,278.85                    55,723,278.85
      III. Provisions for impairment
      1. Balance at the Beginning of the Period                                           0.00                              0.00
      2. Additions for the Period                                                         0.00                              0.00
       (1) Provision                                                                      0.00                              0.00
      3. Decrease for the Period                                                          0.00                              0.00
      (1) Provision                                                                       0.00                              0.00
      4. Balance at the End of the Period                                                 0.00                              0.00
      VI. Carrying Amount
      1. Balance at the End of the Period                                         6,191,475.43                      6,191,475.43
      2. Balance at the Beginning of the Period                                   6,191,475.43                      6,191,475.43


(2). Investment properties whose title certicate has not completed:
     □ Applicable √ N/A

      Other descriptions:
      □ Applicable √ N/A


14. Fixed assets
      Line items
      √ Applicable □ N/A
                                                                                                         Unit: Yuan Currency: RMB
      Item                                    Balance at the End of the Period               Balance at the Beginning of the Year
      Fixed assets                                          4,839,005,169.81                                   4,380,285,156.93
      Disposal of xed assets                                             0.00                                               0.00
      Total                                                 4,839,005,169.81                                   4,380,285,156.93


      Other descriptions:
      □ Applicable √ N/A




204
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                                                                                                                                        2021


(1) Descriptions of xed assets
    √ Applicable □ N/A
                                                                                                                         Unit: Yuan Currency: RMB
                                                                                                                       Electronic
                                                                  Plant and      Machinery and
     Item                                                                                         Motor vehicles      devices and              Total
                                                                   building         equipment
                                                                                                                           others
     I. Original book value
     1. Balance at the Beginning of the Period             3,779,641,227.70    4,557,020,864.75   104,791,052.69   662,702,629.16   9,104,155,774.30
     2. Additions for the Period                            203,437,875.03      658,030,999.87     11,324,491.83   152,589,581.07   1,025,382,947.80
     (1) Acquisition                                         18,022,101.75      180,023,958.68     10,930,219.42   118,048,251.21    327,024,531.06
     (2) Construction in progress transferred               185,415,773.28      478,007,041.19       394,272.41     34,541,329.86    698,358,416.74
     3. Decrease for the Period                                6,879,891.82      95,235,106.60      8,100,214.31    31,926,047.25    142,141,259.98
     (1) Disposal or written-o                                 6,879,891.82      95,235,106.60      7,725,588.18    31,556,254.60    141,396,841.20
    (2)Change in scope of consolidation                              0.00                0.00             0.00      345,584.98         345,584.98
     (3) Others                                                        0.00               0.00       374,626.13         24,207.67        398,833.80
     4. Balance at the End of the Period                   3,976,199,210.91    5,119,816,758.02   108,015,330.21   783,366,162.98   9,987,397,462.12
     II. Accumulated depreciation
     1. Balance at the Beginning of the Period             1,465,544,461.45    2,615,640,767.17    73,194,504.98   450,208,988.22   4,604,588,721.82
     2. Additions for the Period                            168,842,593.41      310,165,425.29     10,522,291.37    51,197,171.85    540,727,481.92
     (1) Provision                                          168,842,593.41      310,165,425.29     10,522,291.37    51,197,171.85    540,727,481.92
     (2) Others                                                        0.00                0.00             0.00             0.00               0.00
     3. Decrease for the Period                                1,123,788.48      75,345,139.96      7,217,655.38    23,229,897.71    106,916,481.53
     (1) Disposal or written-o                                 1,123,788.48      75,345,139.96      6,856,704.38    23,118,823.33    106,444,456.15
    (2)Change in scope of consolidation                              0.00               0.00              0.00        86,866.71         86,866.71
     (2) Others                                                       0.00                0.00       360,951.00         24,207.67        385,158.67
     4. Balance at the End of the Period                   1,633,263,266.38    2,850,461,052.50    76,499,140.97   478,176,262.36   5,038,399,722.21
     III. Impairment provision
     1. Balance at the Beginning of the Period               26,619,980.48       73,464,504.43         77,435.52    19,119,975.12    119,281,895.55
     2. Additions for the Period                                       0.00         848,789.03              0.00      342,933.27        1,191,722.30
     (1) Provision                                                     0.00         848,789.03              0.00      342,933.27       1,191,722.30
     3. Decrease for the Period                                  55,196.03       10,127,065.20         35,856.87      262,929.65      10,481,047.75
     (1) Disposal or written-o                                   55,196.03       10,127,065.20         35,856.87      262,929.65      10,481,047.75
     4. Balance at the End of the Period                     26,564,784.45       64,186,228.26         41,578.65    19,199,978.74    109,992,570.10
     IV. Carrying amount
     1. Carrying amount at the End of the Period           2,316,371,160.08    2,205,169,477.26    31,474,610.59   285,989,921.88   4,839,005,169.81
     2. Carrying amount at the Beginning of the Period     2,287,476,785.77    1,867,915,593.15    31,519,112.19   193,373,665.82   4,380,285,156.93


    The depreciation during the period was RMB540,727,481.92 (RMB518,267,264.56 during the previous period)

(2) Temporarily idled xed assets
    √ Applicable □ N/A
                                                                                                                         Unit: Yuan Currency: RMB
                                                              Original          Accumulated        Provision for         Carrying
     Item                                                                                                                                     Note
                                                            book value           depreciation       impairment            amount
     Plant and building                                  23,926,279.99         14,125,840.52       5,155,770.80      4,644,668.67
     Machinery and equipment                         187,653,120.50           129,431,802.20      40,715,156.36    17,506,161.94
     Electronic devices and others                        3,631,593.98          2,596,927.70        215,250.11         819,416.17
     Total                                           215,210,994.47           146,154,570.42      46,086,177.27    22,970,246.78




                                                                                                                                                205
 (3) Fixed assets leased in under nancing leases
     √ Applicable □ N/A
                                                                                                                        Unit: Yuan Currency: RMB
      Item                                                                                          Carrying Amount at the End of the Period
      Plant and building                                                                                                              1,555,592.77


 (4) Fixed assets whose title certicate has not completed
     √ Applicable □ N/A
                                                                                                                        Unit: Yuan Currency: RMB
      Item                                      Carrying Amount                               Reason for pending for certicate of ownership
      Plant and building                         224,266,766.47                                                               Being in progress


      Other descriptions
      □ Applicable √ N/A


15. Construction in progress
      Line items
      √ Applicable □ N/A
                                                                                                                        Unit: Yuan Currency: RMB
      Item                                         Balance at the End of the Period                    Balance at the Beginning of the Period
      Construction in progress                                        742,533,534.23                                                647,937,496.92
      Construction supplies                                                465,209.52                                                  540,545.50
      Total                                                           742,998,743.75                                                648,478,042.42


      Other descriptions:
      □ Applicable √ N/A

 (1) Descriptions of construction in progress
     √ Applicable □ N/A
                                                                                                                        Unit: Yuan Currency: RMB
                                                      Balance at the End of the Period                 Balance at the Beginning of the Period
      Item                                                      Provision for            carrying                   Provision for          carrying
                                                Gross amount                                        Gross amount
                                                                 impairment               amount                     impairment             amount
      Haibin Pharma Pingshang New Factory 144,364,877.42                0.00 144,364,877.42 229,735,516.02                  0.00 229,735,516.02
      Guangda New Factory Project         179,745,064.48                0.00 179,745,064.48         64,845,632.88           0.00      64,845,632.88
      Fuxing Company Phase I & II Projects
                                                36,580,114.83           0.00    36,580,114.83       95,851,873.91           0.00      95,851,873.91
      and others
      Project of Shijiao New Factory            61,845,397.73           0.00    61,845,397.73 154,752,745.97                0.00 154,752,745.97
      Transformation Project of
                                                19,579,452.17           0.00    19,579,452.17       16,500,619.41           0.00      16,500,619.41
      Pharmaceutical Factory Workshop
      Construction Project for Microsphere
      Workshop (including Gose) of Livzon       15,616,651.12           0.00    15,616,651.12        7,805,534.78           0.00       7,805,534.78
      Group Livzon Pharmaceutical Factory
      P06 Construction Project of Livzon
      Group Livzon                              83,020,966.01           0.00    83,020,966.01        1,559,405.27           0.00       1,559,405.27
      Pharmaceutical Factory
      Project of lyophilized powder injection
                                                70,673,332.62           0.00    70,673,332.62        8,495,072.05           0.00       8,495,072.05
      workshop




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                                                                                         Balance at the End of the Period                                                 Balance at the Beginning of the Period
     Item                                                                                               Provision for                           carrying                                       Provision for                             carrying
                                                                               Gross amount                                                                         Gross amount
                                                                                                         impairment                              amount                                         impairment                                amount
     P09 Construction Project of Livzon
     Group Livzon                                                             54,924,595.61                            0.00          54,924,595.61                       307,744.41                          0.00                  307,744.41
     Pharmaceutical Factory
     P04/P05 Construction Project of
     Livzon Group Livzon Pharmaceutical                                            257,441.66                          0.00                257,441.66                              0.00                     0.00                             0.00
     Factory
     Technology transformation project
     for Microsphere Phase II of Shanghai                                     10,123,776.54                            0.00          10,123,776.54                                 0.00                      0.00                            0.00
     Livzon
     Others                                                                   65,971,204.50                 169,340.46               65,801,864.04                 68,252,692.68                169,340.46                  68,083,352.22
     Total                                                                  742,702,874.69                  169,340.46 742,533,534.23 648,106,837.38                                            169,340.46 647,937,496.92


(1) Changes in signicant construction in progress during the period
    √ Applicable □ N/A
                                                                                                                                                                                                    Unit: Yuan Currency: RMB
                                                                                                                   Accumulated     Of which:      Interest                                         Percentage of
                                                      Balance
                                                                                                                        amount       Interest capitalised    Balance at the                     accumulated cost
                                                         at the    Additions for      Transferred         Other                                                                    Budgeted                         Construction     Sources of
     Name of Project                                                                                                      of the capitalised      rate for      End of the                         incurred over
                                                    Beginning         the Period     to xed asset     deduction                                                                      amount                         progress         funds
                                                                                                                        interest      for the   the Period          Period                      budgeted amount
                                                    of the Year
                                                                                                                     capitalised      Period          (%)                                                   (%)
                                                                                                                                                                                                                    Completion of Self-funding
     Haibin Pharma Pingshang New Factory        229,735,516.02     85,431,217.12   134,074,241.43 36,727,614.29            0.00         0.00         0.00 144,364,877.42 1,037,000,000.00                 58.19
                                                                                                                                                                                                                    some projects    and funds raised
                                                                                                                                                                                                                    Under
     Guangda New Factory Project                 64,845,632.88    114,899,431.60             0.00          0.00            0.00         0.00         0.00 179,745,064.48      646,000,000.00              27.82                      Self-funding
                                                                                                                                                                                                                    construction
     Fuxing Company Phase I & II Projects and                                                                                                                                                                       Completion of
                                                 95,851,873.91     73,773,985.30   133,045,744.38           0.00           0.00         0.00         0.00    36,580,114.83    378,090,800.00              67.07                      Self-funding
     others                                                                                                                                                                                                         some projects
                                                                                                                                                                                                                    Completion of Self-funding
     Project of Shijiao New Factory             154,752,745.97     65,846,744.88   158,754,093.12           0.00           0.00         0.00         0.00    61,845,397.73    377,005,000.00              59.88
                                                                                                                                                                                                                    some projects    and funds raised
     Transformation Project of Pharmaceutical                                                                                                                                                                       Completion of
                                                 16,500,619.41     44,486,202.38    41,407,369.62           0.00           0.00         0.00         0.00    19,579,452.17    306,558,388.48              38.01                      Self-funding
     Factory Workshop                                                                                                                                                                                               some projects
     Construction Project for Microsphere
                                                                                                                                                                                                                    Completion of Self-funding
     Workshop (including Gose) of Livzon          7,805,534.78     10,557,699.98     2,746,583.64           0.00           0.00         0.00         0.00    15,616,651.12    262,445,000.00              53.95
                                                                                                                                                                                                                    some projects    and funds raised
     Group Livzon Pharmaceutical Factory
     P06 Construction Project of Livzon Group                                                                                                                                                                       Under
                                                  1,559,405.27     81,461,560.74             0.00           0.00           0.00         0.00         0.00    83,020,966.01    117,710,000.00              70.53                      Self-funding
     Livzon Pharmaceutical Factory                                                                                                                                                                                  construction
     Project of lyophilized powder injection                                                                                                                                                                        Under            Self-funding
                                                  8,495,072.05     62,178,260.57             0.00          0.00            0.00         0.00         0.00    70,673,332.62    143,500,000.00              49.25
     workshop                                                                                                                                                                                                       construction     and funds raised
     P09 Construction Project of Livzon Group                                                                                                                                                                       Under
                                                   307,744.41     203,607,526.48   148,990,675.28           0.00           0.00         0.00         0.00    54,924,595.61    296,580,000.00              68.76                      Self-funding
     Livzon Pharmaceutical Factory                                                                                                                                                                                  construction
     P04/P05 Construction Project of Livzon                                                                                                                                                                         Under
                                                          0.00       257,441.66              0.00          0.00            0.00         0.00         0.00      257,441.66     126,880,000.00                 0.2                     Self-funding
     Group Livzon Pharmaceutical Factory                                                                                                                                                                            construction
     Technology transformation project for                                                                                                                                                                          Under
                                                          0.00     10,123,776.54             0.00           0.00           0.00         0.00         0.00    10,123,776.54     40,500,000.00                 25                      Self-funding
     Microsphere Phase II of Shanghai Livzon                                                                                                                                                                        construction
     Others                                      68,252,692.68     86,619,992.91    79,339,709.27   9,561,771.82           0.00         0.00         0.00    65,971,204.50                --                  -- --                  Self-funding
     Total                                      648,106,837.38    839,243,840.16   698,358,416.74 46,289,386.11            0.00         0.00         0.00 742,702,874.69 3,732,269,188.48                      / /                   /



    Other deduction mainly refers to transfer of long-term deferred expenses.
    Other descriptions
    □ Applicable √ N/A



                                                                                                                                                                                                                                              207
16. Right-of-use assets
      √ Applicable □ N/A
                                                                                                     Unit: Yuan Currency: RMB
      Item                                                            Plant and building                               Total
      I. Original book value:
      1. Balance at the Beginning of the Period                           29,133,700.11                       29,133,700.11
      2. Addition during the Period                                       54,745,418.58                       54,745,418.58
      (1) Leasing                                                         54,745,418.58                       54,745,418.58
      3. Decrease during the Period                                       13,918,600.42                       13,918,600.42
      4. Balance at the End of the Period                                 69,960,518.27                       69,960,518.27
      II. Accumulated depreciation
      1. Balance at the Beginning of the Period                           11,103,567.42                       11,103,567.42
      2. Addition during the Period                                       26,000,791.57                       26,000,791.57
      (1) Provision                                                       26,000,791.57                       26,000,791.57
      3. Decrease during the Period                                       13,918,600.41                       13,918,600.41
      4. Balance at the End of the Period                                 23,185,758.58                       23,185,758.58
      III. Provision for impairment
      1. Balance at the Beginning of the Period                                    0.00                                0.00
      2. Addition during the Period                                                0.00                                0.00
      3. Decrease during the Period                                                0.00                                0.00
      4. Balance at the End of the Period                                          0.00                                0.00
      IV. Carrying amount
      1. Carrying amount at the End of the Period                         46,774,759.69                       46,774,759.69
      2. Carrying amount at the Beginning of the Period                   18,030,132.69                       18,030,132.69


      Other descriptions:
      As of 31 December 2021, the Company recognised lease expenses related to short-term leases and the leases of low value
      assets of RMB7.4548 million.




208
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17. Intangible assets
(1). Descriptions of intangible assets
     √ Applicable □ N/A
                                                                                                                               Unit: Yuan Currency: RMB
                                                                                   Patent and
                                                                                                               Trademark
     Item                                                     Land use right        technical      Software                       Others               Total
                                                                                                                    rights
                                                                                   know-how
     I. Original book value
     1. Balance at the Beginning of the Period               423,486,347.87    487,561,318.73 71,984,555.87 62,765,000.00 10,985,294.53     1,056,782,517.00
     2. Additions for the Period                                       0.00     55,624,707.48   7,354,491.28     4,716.98            0.00     62,983,915.74
     (1) Acquisition                                                   0.00      3,353,641.70   7,354,491.28     4,716.98            0.00     10,712,849.96
     (2) Internal R&D                                                  0.00     52,271,065.78          0.00          0.00            0.00     52,271,065.78
     3. Decrease for the Period                                9,723,610.00     23,372,149.54    106,656.46          0.00            0.00     33,202,416.00
     (1) Disposal or written-o                                 9,723,610.00     16,705,482.54    106,656.46          0.00            0.00     26,535,749.00
     (2) Change in scope of consolidation                              0.00      6,666,667.00          0.00          0.00            0.00      6,666,667.00
     4. Balance at the End of the Period                     413,762,737.87    519,813,876.67 79,232,390.69 62,769,716.98 10,985,294.53     1,086,564,016.74
     II. Accumulated amortisation
     1. Balance at the Beginning of the Period               118,722,931.47    339,090,486.99 51,118,566.22 62,765,000.00    4,485,661.92    576,182,646.60
     2. Additions for the Period                               8,560,052.42     38,940,864.05   5,226,425.06       196.55    1,098,529.45     53,826,067.53
     (1) Provision                                             8,560,052.42     38,940,864.05   5,226,425.06       196.55    1,098,529.45     53,826,067.53
     3. Decrease for the Period                                4,285,813.60      8,395,834.01     57,098.93          0.00            0.00     12,738,746.54
     (1) Disposal or written-o                                 4,285,813.60      7,895,833.97     57,098.93          0.00            0.00     12,238,746.50
     (2) Change in scope of consolidation                              0.00       500,000.04           0.00          0.00            0.00        500,000.04
     4. Balance at the End of the Period                     122,997,170.29    369,635,517.03 56,287,892.35 62,765,196.55    5,584,191.37    617,269,967.59
     III. Provision for impairment
     1. Balance at the Beginning of the Period                   981,826.94     11,530,127.41           0.00         0.00            0.00     12,511,954.35
     2. Additions for the Period                                       0.00              0.00           0.00         0.00            0.00               0.00
     (1)Provision                                                      0.00              0.00           0.00         0.00            0.00               0.00
     3. Decrease for the Period                                        0.00              0.00           0.00         0.00            0.00               0.00
     4. Balance at the End of the Period                         981,826.94     11,530,127.41           0.00         0.00            0.00     12,511,954.35
     IV. Carrying amount
     1. Carrying amount at the End of the Period             289,783,740.64    138,648,232.23 22,944,498.34      4,520.43    5,401,103.16    456,782,094.80
     2. Carrying amount at the Beginning of the Period       303,781,589.46    136,940,704.33 20,865,989.65          0.00    6,499,632.61    468,087,916.05


     The amortisation for the period was RMB53,826,067.53 (RMB 14,424,153.41 for the previous period).
     The proportion of intangible assets created due to the internal R&D in the balance of intangible assets at the End of the Period
     is 24.65%

(2). Intangible assets pending for certicates of ownership
     √ Applicable □ N/A
                                                                                                                               Unit: Yuan Currency: RMB
     Item                                                Carrying amount                              Reason for pending for certicate of ownership
     Land use rights                                        4,164,314.22                                                               Being in progress


     Other descriptions
     √ Applicable □ N/A

     The land use rights represent the state-owned land use rights obtained by the Company in accordance with PRC laws in China,
     and the term of grant will be 50 years commencing from the date of obtaining the land use rights.


                                                                                                                                                        209
18. Development Expenditure
      √ Applicable □ N/A
                                                                                                                             Unit: Yuan Currency: RMB
                                                             Increase for the Period                  Decrease for the Period
                             Balance at the                                                                       Recognised in            Balance at
                                                        Internal
      Item                    Beginning of                                   Other    Recognised as               prot and loss            the End of
                                                   development
                                the Period                                increases intangible assets                for current           the Period
                                                    expenditure
                                                                                                                          period
      Chemical drug
                            138,564,375.18     133,042,483.22                   0.00       13,033,255.30          79,161,936.76        179,411,666.34
      preparation
      Biologics             213,261,084.53       51,186,161.19                  0.00       38,805,707.06          12,539,408.55        213,102,130.11
      Vaccine                         0.00     314,172,937.62                   0.00                  0.00                   0.00      314,172,937.62
      APIs and others        47,294,144.07       43,542,133.89                  0.00          432,103.42          10,097,472.90         80,306,701.64
      Total                 399,119,603.78     541,943,715.92                   0.00       52,271,065.78         101,798,818.21        786,993,435.71


      Other descriptions:


                                               Time for                                                                Progress of research and
      Item                                     commencement of           Specic basis of capitalisation                development as at the End
                                               capitalisation                                                          of the Period
      Chemical drug preparation                Clinical trial            Obtain approval for clinical trial            Clinical stage
      Biologics                                Clinical trial            Obtain approval for clinical trial            Clinical stage
      Vaccine                                  Clinical trial            Obtain approval for clinical trial            Clinical stage
      APIs and others                          Pilot stage               Pilot related information                     Post-pilot stage


19. Goodwill
(1). Original book value of goodwill
     √ Applicable □ N/A
                                                                                                                             Unit: Yuan Currency: RMB
                                                                                                                   Decrease for the
                                                                                       Increase for the Period
                                                                     Balance at the                                         Period          Balance at
      Name of investee or matter from which goodwill arose            Beginning of      Arose from                                          the End of
                                                                        the Period        business     Others Disposal Others               the Period
                                                                                       combination
      Shanghai Livzon Pharmaceutical Manufacturing Co., Ltd.          2,045,990.12             0.00      0.00         0.00      0.00      2,045,990.12
      Zhuhai FTZ Livzon Hecheng Pharmaceutical
                                                                      3,492,752.58             0.00      0.00         0.00      0.00      3,492,752.58
      Manufacturing Co., Ltd.
      Sichuan Guangda Pharmaceutical Manufacturing Co., Ltd.         13,863,330.24             0.00      0.00         0.00      0.00     13,863,330.24
      Livzon Group Xinbeijiang Pharmaceutical Manufacturing
                                                                      7,271,307.03             0.00      0.00         0.00      0.00      7,271,307.03
      Inc.
      Livzon Group Fuzhou Fuxing Pharmaceutical Co., Ltd.            46,926,155.25             0.00      0.00         0.00      0.00     46,926,155.25
      Livzon Group Livzon Pharmaceutical Factory                     47,912,269.66             0.00      0.00         0.00      0.00     47,912,269.66
      Livzon Group                                                 395,306,126.41              0.00      0.00         0.00      0.00 395,306,126.41
      Shenzhen Haibin Pharmaceutical Co., Ltd.                       91,878,068.72             0.00      0.00         0.00      0.00     91,878,068.72
      Joincare Daily-Use & Health Care Co., Ltd.                      1,610,047.91             0.00      0.00         0.00      0.00      1,610,047.91
      Shenzhen Taitai Pharmaceutical Co., Ltd.                         635,417.23              0.00      0.00         0.00      0.00       635,417.23
      Health Pharmaceuticals (China) Limited                         23,516,552.65             0.00      0.00         0.00      0.00     23,516,552.65
      Shenzhen Hiyeah Industry Co., Ltd                               6,000,000.00             0.00      0.00         0.00      0.00      6,000,000.00
      Jiaozuo Joincare Bio Technological Co., Ltd.                       92,035.87             0.00      0.00         0.00      0.00        92,035.87
      Total                                                        640,550,053.67              0.00      0.00         0.00      0.00 640,550,053.67


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(2). Provision for impairment of goodwill
     √ Applicable □ N/A
                                                                                                             Unit: Yuan Currency: RMB
                                              Balance at the    Increase for the Period   Decrease for the Period     Balance at the
     Name of investee or the matter of
                                               Beginning of                                                                  End of
     goodwill arisen                                            Provision       Others     Disposal        Others
                                                 the Period                                                              the Period
     Livzon Group Xinbeijiang
                                               7,271,307.03          0.00         0.00          0.00         0.00      7,271,307.03
     Pharmaceutical Manufacturing Inc.
     Livzon Group Fuzhou Fuxing
                                              11,200,000.00          0.00         0.00          0.00         0.00     11,200,000.00
     Pharmaceutical Co., Ltd.
     Shenzhen Hiyeah Industry Co., Ltd         6,000,000.00          0.00         0.00          0.00         0.00      6,000,000.00
     Joincare Daily-Use & Health Care
                                               1,610,047.91          0.00         0.00          0.00         0.00      1,610,047.91
     Co., Ltd.
     Total                                    26,081,354.94          0.00         0.00          0.00         0.00     26,081,354.94


(3). Relevant information regarding the asset portfolio and set of asset portfolios to which the goodwill belongs
    √ Applicable □ N/A

    Goodwill of the Company arose from its business combination involving enterprises not under common control in previous
    years.

(4). Descriptions of the process of goodwill impairment testing, key parameters (such as the growth rate of the forecast period, the
     growth rate of the stable period, the prot rate, the discount rate and the forecast period, etc. when the present value of future
     cash ows are expected, if applicable) and the recognition method of the impairment losses on goodwill
     √ Applicable □ N/A

    On the balance sheet date, the Company conducted impairment test on goodwill and adopted the asset groups related to
    goodwill to estimate the present value of the future cash ow when estimating the recoverable amount of the investment cost.
    The estimated future cash flow of asset groups is calculated according to the five-year financial budget plan made by the
    management, the cash ows in the years beyond the ve-year budget plan remain stable.

    Key assumptions of discounted future cash ow for goodwill impairment test are as follows:

    For the calculation of estimated present value of future cash flow of the asset groups related to goodwill of Livzon Group,
    key assumptions are a gross margin of 63.24%-63.43% and a business revenue growth rate of 0-9.07% as well as a cash
    flow discount rate of 12.99%. The management took into account historical conditions and predictions for future market
    development in making the above assumptions.

    For the calculation of estimated present value of future cash flow of the asset groups related to goodwill of Shenzhen
    Haibin Pharmaceutical Co., Ltd., key assumptions are a gross margin of 58.33%-59.13% and a business revenue growth
    rate of 0-5.27% as well as a cash flow discount rate of 11.78%. The management took into account historical conditions and
    predictions for future market development in making the above assumptions.

     As tested, the management of the Company expects that no impairment provision is needed during the Reporting Period.

(5). The impact of goodwill impairment test
     □ Applicable √ N/A

     Other descriptions:
     □ Applicable √ N/A




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20. Long-term deferred expenses
      √ Applicable □ N/A
                                                                                                                              Unit: Yuan Currency: RMB
                                                    Balance at the                                                                      Balance at the
                                                                            Increase for           Amortisation           Other
      Item                                           Beginning of                                                                              End of
                                                                              the Period          for the Period        decrease
                                                       the Period                                                                          the Period
      Renovation costs of oces                      23,058,574.53          7,850,405.20           3,332,198.97 636,080.74               26,940,700.02
      Renovation costs of plants                    82,549,157.36          6,780,069.68          10,953,783.19        38,348.62         78,337,095.23
      Plants reconstruction project                 38,063,547.08         35,995,971.86          13,691,355.23              0.00        60,368,163.71
      Certication costs of GMP project                    432,295.36                   0.00          120,640.57             0.00           311,654.79
      Others                                        25,946,027.65         24,703,242.62          15,891,143.09              0.00        34,758,127.18
      Total                                        170,049,601.98         75,329,689.36          43,989,121.05 674,429.36             200,715,740.93


21. Deferred income tax assets/ deferred income tax liabilities
(1). Deferred income tax assets without osetting
     √ Applicable □ N/A
                                                                                                                              Unit: Yuan Currency: RMB
                                                                         Balance at the End of the Period         Balance at the Beginning of the Period
                                                                          Deductible                Deferred            Deductible             Deferred
      Item
                                                                          temporary               income tax            temporary            income tax
                                                                           dierence                   assets             dierence                assets
      Provision for impairment of assets                           323,372,877.26              54,704,601.96        348,200,387.60       59,268,643.32
      Accrued expenses                                             945,774,497.50             166,481,490.01        889,520,767.20      148,230,373.91
      Deductible losses                                            497,850,865.29              84,167,365.69        183,558,004.28       33,002,594.88
      Deferred income                                              375,321,674.10              60,145,851.14        395,262,933.81       63,372,920.07
      Unrealised gains from intra-company transactions             560,934,298.63              84,185,529.66        617,172,492.65      101,762,569.57
      Changes in fair value of other equity instruments            146,653,568.40              36,663,392.10        116,897,135.04       29,224,283.76
      Share incentive costs                                            77,872,943.63           11,933,224.52         55,129,055.25         8,614,498.87
      Changes in fair value of nancial assets held for trading          6,918,505.67            1,158,336.82               5,004.11            1,229.82
      Other deductible temporary dierence                          282,821,670.90              53,103,074.81        148,783,538.98       25,421,355.03
      Total                                                       3,217,520,901.38            552,542,866.71      2,754,529,318.92      468,898,469.23


(2). Deferred income tax liabilities without osetting
     √ Applicable □ N/A
                                                                                                                              Unit: Yuan Currency: RMB
                                                                         Balance at the End of the Period         Balance at the Beginning of the Period
                                                                            Taxable                  Deferred              Taxable              Deferred
      Item
                                                                          temporary               income tax             temporary           income tax
                                                                          dierence                  liabilities          dierence              liabilities
      Changes in fair value of nancial assets held for trading         19,970,547.94            3,215,329.05         18,644,355.09         3,365,228.40
      Accelerated depreciation of xed assets                       752,180,706.08             114,114,492.09        564,348,918.93       85,208,619.02
      Changes in fair value of other equity instruments            359,110,036.65              70,405,084.25        497,704,254.93       92,895,008.26
      Unrealised gains from intra-company transactions             105,940,000.00              20,791,000.00        105,940,000.00       20,791,000.00
      Total                                                       1,237,201,290.67            208,525,905.39      1,186,637,528.95      202,259,855.68


(3). Deferred income tax assets or liabilities listed as net amount after oset
     □ Applicable √ N/A




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(4). Details of unrecognised deferred tax assets
     √ Applicable □ N/A
                                                                                                          Unit: Yuan Currency: RMB
                                                                           Balance at the End            Balance at the Beginning
     Item
                                                                                of the Period                        of the Period
     Deductible temporary dierence                                             175,707,417.84                      316,754,374.35
     Deductible losses                                                       1,365,909,940.62                     1,116,620,167.81
     Total                                                                   1,541,617,358.46                     1,433,374,542.16


(5). Deductible loss of deferred income tax assets not recognised will be due in the following years
     √ Applicable □ N/A
                                                                                                          Unit: Yuan Currency: RMB
                               Balance at the End of                 Balance at the Beginning
     Year                                                                                                                    Note
                                          the Period                             of the Period
     2021                                          0.00                        108,384,223.02
     2022                            129,386,282.40                            141,475,583.52
     2023                            182,300,761.96                            197,436,530.74
     2024                            385,138,859.92                            385,190,825.59
     2025                            254,360,863.53                            277,697,732.91
     2026                            389,994,598.37                                       0.00
     Indenite                         24,728,574.44                               6,435,272.03
     Total                         1,365,909,940.62                          1,116,620,167.81                                     /


    Other descriptions:
    □ Applicable √ N/A


22. Other non-current assets
    √ Applicable □ N/A
                                                                                                          Unit: Yuan Currency: RMB
                                        Balance at the End of the Period                Balance at the Beginning of the Period
     Item                      Gross carrying Provision for                       Gross carrying   Provision for
                                                            Carrying amount                                      Carrying amount
                                      amount impairment                                  amount     impairment
     Term deposit and
                               52,127,500.00              0.00    52,127,500.00             0.00           0.00              0.00
     interests
     Remaining VAT credit      56,384,552.60              0.00    56,384,552.60    33,826,183.51           0.00     33,826,183.51
     Prepayment for
     acquisition of project   491,703,933.59              0.00   491,703,933.59 300,277,977.91             0.00    300,277,977.91
     and equipment
     Prepayment for
     acquisition of            63,368,017.61              0.00    63,368,017.61    39,453,749.30           0.00     39,453,749.30
     technical know-how
     Total                    663,584,003.80              0.00   663,584,003.80 373,557,910.72             0.00    373,557,910.72




                                                                                                                                 213
23. Short-term loans
 (1) Classication of short-term loans
     √ Applicable □ N/A
                                                                                                               Unit: Yuan Currency: RMB
      Item                                       Balance at the End of the Period                Balance at the Beginning of the Period
      Loans on credit                                          1,666,838,964.15                                      1,850,000,000.00
      Loans on guarantee                                         851,645,870.94                                        260,942,804.06
      Total                                                    2,518,484,835.09                                      2,110,942,804.06


 (2) Outstanding and overdue short-term loans
     □ Applicable √ N/A

      Other descriptions:
      □ Applicable √ N/A

24. Financial liabilities held for trading
      √ Applicable □ N/A
                                                                                                               Unit: Yuan Currency: RMB
                                                 Balance at the Beginning    Increase for the Decrease for the Balance at the End
      Item
                                                             of the Period            Period           Period       of the Period
      Financial liabilities held for trading                        212.07          143,090.17               0.00          143,302.24
      Of which:
      Derivative nancial liabilities                                212.07          143,090.17               0.00          143,302.24
      Total                                                         212.07          143,090.17               0.00          143,302.24


      Other descriptions:
      Derivative financial liabilities represent foreign currency forward contracts, loss from unexpired contracts measured at fair
      value was recognised as nancial liabilities held for trading at balance sheet date.

25. Bills payables
      √ Applicable □ N/A
                                                                                                               Unit: Yuan Currency: RMB
      Type                                            Balance at the End of the Period           Balance at the Beginning of the Period
      Bank acceptance bills                                          1,582,386,767.93                                1,087,759,353.31
      Total                                                          1,582,386,767.93                                1,087,759,353.31


      The total of bills payable due but not yet paid during the period is RMB 0.00.

26. Accounts payables
(1). Presentations of accounts payable
     √ Applicable □ N/A
                                                                                                               Unit: Yuan Currency: RMB
      Item                                            Balance at the End of the Period           Balance at the Beginning of the Period
      Within 1year                                                    809,539,858.35                                   770,352,354.22
      Over 1 year                                                       62,013,352.16                                   62,279,852.31
      Total                                                           871,553,210.51                                   832,632,206.53


(2). Signicant accounts payable aged more than one year
     □ Applicable √ N/A

      Other descriptions:
      □ Applicable √ N/A


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27. Contract liabilities
(1). Descriptions of contract liabilities
     √ Applicable □ N/A
                                                                                                             Unit: Yuan Currency: RMB
      Item                                          Balance at the End of the Period           Balance at the Beginning of the Period
      Within 1 year                                                 208,025,612.34                                   125,816,111.93
      Over 1 year                                                        26,115,089.95                                  7,606,242.10
      Total                                                         234,140,702.29                                   133,422,354.03


(2). Signicant changes in the carrying amount during the Reporting Period and reasons therefor
     □ Applicable √ N/A

     Other descriptions:
     √ Applicable □ N/A

     As at the End of the Period, there was no significant contract liabilities aged over 1 year; the amount of income recognised
     during the Period which was included in the carrying amount of the contract liabilities at the Beginning of the Period was RMB
     89,991,623.98.


28. Employee benefits payables
(1) Descriptions of employee benets payables
    √ Applicable □ N/A
                                                                                                             Unit: Yuan Currency: RMB
                                             Balance at the Beginning       Increase for the    Decrease for the Balance at the End
      Item
                                                         of the Period               Period              Period       of the Period
      I. Short-term salary                            474,099,711.48 1,842,060,745.21 1,842,354,099.29               473,806,357.40
      II. Post-resignation benets-dened
                                                          981,049.03        127,168,164.64      127,807,489.87           341,723.80
      contribution plans
      III. Dismissal benets                             1,441,038.00           3,266,253.11        3,424,549.11         1,282,742.00
      Total                                           476,521,798.51 1,972,495,162.96 1,973,586,138.27               475,430,823.20


(2) Descriptions of Short-term remuneration
    √ Applicable □ N/A
                                                                                                             Unit: Yuan Currency: RMB
                                             Balance at the Beginning       Increase for the   Decrease for the   Balance at the End
      Item
                                                         of the Period               Period             Period         of the Period
      I. Salaries, bonuses, allowances and
                                                      317,711,687.49 1,516,182,208.88 1,508,769,918.24               325,123,978.13
      subsidies
      II. Employee welfare                              5,159,583.88         67,739,188.41       67,546,637.63          5,352,134.66
      III. Social insurance                               648,169.59         57,770,394.32       57,849,075.16           569,488.75
      Of which: Medical insurances                        479,191.24         50,045,894.76       50,057,523.09           467,562.91
      Work-related injury insurances                      120,278.27          3,269,300.48        3,326,867.38             62,711.37
      Maternity insurances                                  48,700.08         4,455,199.08        4,464,684.69             39,214.47
      IV. Housing provident fund                        1,812,818.16         54,197,763.39       54,516,861.67          1,493,719.88
      V. Labour union fees and employee
                                                          268,119.84          5,341,149.46        5,067,704.70           541,564.60
      education fees
      VI. Special funds of the share
                                                      148,499,332.52        140,830,040.75      148,603,901.89       140,725,471.38
      ownership scheme
      Total                                           474,099,711.48 1,842,060,745.21 1,842,354,099.29               473,806,357.40




                                                                                                                                 215
 (3) Dened contribution plan
     √ Applicable □ N/A
                                                                                                              Unit: Yuan Currency: RMB
                                              Balance at the Beginning       Increase for the   Decrease for the   Balance at the End
      Item
                                                          of the Period               Period             Period         of the Period
      Post-resignation benets
      Of which: 1. Basic pension insurance                  891,463.38       122,881,458.07      123,469,339.38           303,582.07
      2. Unemployment insurance                              89,585.65         4,286,706.57        4,338,150.49             38,141.73
      Total                                                 981,049.03       127,168,164.64      127,807,489.87           341,723.80


      Other descriptions:
      √ Applicable □ N/A

      The Company participates in pension insurance and unemployment insurance plans established by the government in
      accordance with relevant requirements. According to the plans, the Company makes contributions to these plans in accordance
      with relevant requirements of the local government. Save for the above contributions, the Company no longer undertakes
      further payment obligation. The corresponding cost is charged to the prot or loss for the current period or the cost of relevant
      assets when it occurs.


29. Taxes payables
      √ Applicable □ N/A
                                                                                                              Unit: Yuan Currency: RMB
      Item                                             Balance at the End of the Period         Balance at the Beginning of the Period
      Value added tax                                                      91,860,518.74                               73,761,952.33
      Urban maintenance and construction tax                               10,047,715.71                                 8,540,571.43
      Enterprise income tax                                               145,106,168.70                              197,934,880.78
      Property tax                                                          2,178,644.31                                 3,335,394.01
      Land use tax                                                          1,716,626.70                                 1,861,774.91
      Individual income tax                                                 9,991,974.56                                 5,176,424.28
      Stamp duty                                                             676,792.62                                   573,412.18
      Education surcharges                                                  6,594,414.24                                 5,877,893.41
      Others                                                                2,445,327.83                                 1,279,879.11
      Total                                                               270,618,183.41                              298,342,182.44


30. Other payables
      Line items
      √ Applicable □ N/A
                                                                                                              Unit: Yuan Currency: RMB
      Item                                             Balance at the End of the Period         Balance at the Beginning of the Period
      Dividends payable                                                     6,951,984.46                                 8,418,590.50
      Other payables                                                  3,285,456,005.33                              2,839,269,475.09
      Total                                                           3,292,407,989.79                              2,847,688,065.59




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    Dividends payable
    √ Applicable □ N/A
                                                                                                          Unit: Yuan Currency: RMB
                                                                  Balance at the End                     Balance at the Beginning
     Item
                                                                       of the Period                                 of the Period
     Dividends on ordinary shares                                         20,174.46                                     20,174.46
     Dividends payable--Qingyuan Xinbeijiang
                                                                       1,200,710.00                                  1,200,710.00
     (Group) Company
     Dividends payable--Other legal persons and
                                                                       3,311,300.00                                  3,311,300.00
     individual shares of subsidiaries
     Dividends payable--Sta shares of subsidiaries                     2,419,800.00                                  2,419,800.00
     Dividends payable--Zhuhai Zhong Hui Yuan
                                                                                0.00                                 1,466,606.04
     Investment Partnership (Limited Partnership)
     Total                                                             6,951,984.46                                  8,418,590.50


    Other payables
(1) Other payables by nature
    √ Applicable □ N/A
                                                                                                          Unit: Yuan Currency: RMB
     Item                                            Balance at the End of the Period       Balance at the Beginning of the Period
     Oce expenses                                                     66,603,733.56                                54,902,934.12
     Deposits under guarantees                                        85,316,947.15                                84,683,431.06
     Business promotion expenses                                   1,385,121,675.36                             1,188,695,632.04
     Technology transfer funds                                        10,000,000.00                                10,072,731.53
     Accrued expenses                                              1,696,272,218.54                             1,432,467,048.13
     Others                                                           42,141,430.72                                68,447,698.21
     Total                                                         3,285,456,005.33                             2,839,269,475.09


    The obligations of repurchasing restricted shares of the directors, the senior management and their spouses amounted
    RMB0.00 at the End of the Period.

(2) Signicant other payables aged over 1 year
    □ Applicable √ N/A

    Other descriptions:
    √ Applicable □ N/A
    Of which, the breakdown of accrued expenses was as follows:


                                                                                                          Reason for outstanding
     Item                                               31 December 2021         31 December 2020
                                                                                                          at the End of the Period
     Utilities expenses                                      23,611,733.95              28,252,339.28                Not yet paid
     Research expenses                                     122,637,625.45               31,246,236.75                Not yet paid
     Business development and promotion expenses          1,459,695,485.76        1,282,377,335.13                   Not yet paid
     Audit and information disclosure expenses                4,893,299.88               3,876,590.50                Not yet paid
     Others                                                  85,434,073.50              86,714,546.47                Not yet paid
     Total                                                1,696,272,218.54        1,432,467,048.13




                                                                                                                              217
31. Non-current liabilities due within one year
      √ Applicable □ N/A
                                                                                                             Unit: Yuan Currency: RMB
      Item                                                 Balance at the End of the Period    Balance at the Beginning of the Period
      Lease liabilities due within one year                                  21,295,233.00                              8,539,077.05
      Long-term loans and interest due within 1 year                         70,280,833.33                                       0.00
      Total                                                                  91,576,066.33                              8,539,077.05


32. Other current liabilities
      √ Applicable □ N/A
                                                                                                             Unit: Yuan Currency: RMB
      Item                                                 Balance at the End of the Period    Balance at the Beginning of the Period
      Tax for items pending for settlement                                   15,626,224.29                              6,267,034.79
      Total                                                                  15,626,224.29                              6,267,034.79


      Other descriptions:
      □ Applicable √ N/A


33. Long-term loans
 (1) Classication of long-term loans
     √ Applicable □ N/A
                                                                                                             Unit: Yuan Currency: RMB
                                                                                                 Balance at the
                                                  Balance at the End
      Item                                                               interest rate range   Beginning of the    interest rate range
                                                       of the Period
                                                                                                        Period
      Loans on credit                                 897,061,086.11         3.45%-3.70%        360,324,027.48         3.55%-3.60%
      Long-term loans due within 1 year               -70,280,833.33                                       0.00
      Total                                           826,780,252.78                            360,324,027.48


      Other descriptions, including interest rate range:
      □ Applicable √ N/A


34. Lease liabilities
      √ Applicable □ N/A
                                                                                                             Unit: Yuan Currency: RMB
      Item                                                 Balance at the End of the Period    Balance at the Beginning of the Period
      Amount payable under lease                                            46,367,027.32                             18,356,857.09
      Lease liabilities due within one year                                -21,295,233.00                             -8,539,077.05
      Total                                                                 25,071,794.32                               9,817,780.04


      Other descriptions:
      During January to December 2021, the amount of interest expenses of lease liabilities was RMB2.2757 million, which was
      recorded in nance expenses – interest expenses.




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35. Deferred income
   Deferred income
   √ Applicable □ N/A
                                                                                                                                                                         Unit: Yuan Currency: RMB
                                             Balance at the Beginning                     Increase for the                  Decrease for the             Balance at the End
    Item                                                                                                                                                                                          Reason
                                                         of the Period                             Period                            Period                   of the Period
    Government grants                                         467,562,770.49                53,936,373.61                     87,955,791.70                   433,543,352.40                                 /
    Total                                                     467,562,770.49                53,936,373.61                     87,955,791.70                   433,543,352.40                                 /


   Projects involving government grants:
   √ Applicable □ N/A
                                                                                                                                                                         Unit: Yuan Currency: RMB
                                                                                                                                   Amount
                                                                                                                Amount                              Amount
                                                                                          Balance at the                         charged to                                        Balance
                                                                                                           of additional                          charged to                                Related to assets/
    Liabilities                                                                              Beginning                       Non-operating                   Other changes       at the End
                                                                                                                grant for                     Other income                                  Related to income
                                                                                             of the Year                     income for the                                   of the Period
                                                                                                              the Period                      for the Period
                                                                                                                                     Period
    Study on the technology of antifungal drug caspofungin
                                                                                           1,500,000.00                0                 0    1,500,000.00              0               0    Related to assets
    (抗真菌药卡泊芬净工艺研究)
    Laboratory project of respiratory system inhalation preparation engineering
                                                                                           5,000,000.00                0                 0    1,346,750.00      151,700.00    3,501,550.00   Related to assets
    laboratory project(呼吸系统吸入制剂工程实验室项目)
     Construction of a recycling production base for carbapenem products
                                                                                           3,625,000.00                0                 0               0              0     3,625,000.00   Related to assets
   (碳青霉烯类系列产品循环化生产基地建设)
     Research and development and industrialization of non-steroidal anti-inammatory
     drug Celecoxib capsules                                                               5,000,000.00                0                 0               0    5,000,000.00              0    Related to assets
   (非甾体抗炎药物塞来昔布胶囊研发及产业化)
     Construction of an integrated production line for fully automatic blister-type dry
     powder inhalant micro-lling and winding                                               2,420,000.00                0                 0    1,492,333.34              0      927,666.66    Related to assets
   (全自动泡罩型干粉吸入剂微量灌封与卷绕一体化生产线建设)
     Change in National Science and Technology Major Project* Research funding for
     lipid injection * Baiyunshan Hanfang transfer                                          150,000.00                 0                 0               0              0      150,000.00    Related to assets
   (国家重大专项项目变更*注射脂质研究经费*白云山汉方转入)
    Research on common key technologies for the large-scale development of new
                                                                                            365,700.00                 0                 0               0              0      365,700.00    Related to assets
    inhalation preparations(新型吸入制剂规模化发展共性关键技术研究)
     Large-scale development subsidy for new inhalation preparations
                                                                                           2,262,600.00                0                 0               0              0     2,262,600.00   Related to assets
   (新型吸入制剂规模化发展补助)
    Meropenem special fund subsidy(美罗培南专项资金补助)                                10,000,000.00                0                 0               0 10,000,000.00                0    Related to assets
    Project Subsidy of Meropenem internationalization(美罗培南国际化项目补助)            3,300,000.00                0                 0               0    3,300,000.00              0    Related to assets
     Project Subsidy of Marine mollusk kinetic protein
                                                                                          23,840,000.00                0                 0               0              0    23,840,000.00   Related to assets
   (海洋软体动物动能蛋白项目补助)
    New inhalation drug formulation creation project(新型吸入给药制剂创制项目)          54,154,400.00 13,094,000.00                    0               0              0    67,248,400.00   Related to assets
    Zhimu total sapogenin project(知母总皂甙元项目)                                      8,900,000.00                0                 0               0              0     8,900,000.00   Related to assets
    Glucocorticoid inhalation suspension project(糖皮质混悬液项目)                                  0    3,600,000.00                  0               0              0     3,600,000.00   Related to assets
     Financial appropriations for small molecule peptide projects
                                                                                            399,999.84                 0                 0       80,000.04              0      319,999.80    Related to assets
   (财政拨款用于小分子肽项目)
    Leulu total sterone project(漏芦总甾酮项目)                                          2,500,000.00                0                 0               0              0     2,500,000.00   Related to assets
     R&D of active substances with bone and joint repair and health care functions
                                                                                           1,077,356.16                0                 0      119,706.24              0      957,649.92    Related to assets
   (具有骨关节修复与保健功能的活性物质研发)
     Key technology research and development of budesonide nebulized inhalation
     solution                                                                              4,500,000.00                0                 0    1,991,666.67              0     2,508,333.33   Related to assets
   (布地奈德雾化吸入溶液关键技术研发)
    Return of land holding tax(土地使用税返还)                                           3,674,691.16                0                 0      107,029.74              0     3,567,661.42   Related to assets
    Special Fund for environmental protection of wastewater membrane concentration
                                                                                               9,708.66                0                 0        9,708.66              0               0    Related to assets
    system(废水膜浓缩系统环保专项资金)




                                                                                                                                                                                                         219
                                                                                                                               Amount
                                                                                                               Amount                           Amount
                                                                                         Balance at the                      charged to                                        Balance
                                                                                                          of additional                       charged to                                Related to assets/
       Liabilities                                                                          Beginning                    Non-operating                   Other changes       at the End
                                                                                                               grant for                  Other income                                  Related to income
                                                                                            of the Year                  income for the                                   of the Period
                                                                                                             the Period                   for the Period
                                                                                                                                 Period
        Subsidies for The development of pharmaceutical APIs industry
                                                                                         41,960,547.60              0                0    1,219,192.66              0    40,741,354.94   Related to assets
      (医药原料药行业发展支持资金补助)
       Innovation voucher(Jingjin Filter Press Equipment)(创新券(景津压滤设备))      313,332.99               0                0       80,000.20              0      233,332.79    Related to assets
       Xinxiang High-tech Project Fund Support(新乡高新技术项目资金扶持)                1,917,508.44              0                0       56,397.36              0     1,861,111.08   Related to assets
        Hepatitis B vaccine methanol yeast expression system
                                                                                           500,000.00               0                0      500,000.00              0               0    Related to assets
      (乙肝疫苗甲醇酵母表达系统)
       New recombinant protein vaccine technology platform and Industrialization of
                                                                                          9,000,002.00              0                0    9,000,002.00              0               0    Related to assets
       Cervical Cancer Vaccine(新型重组蛋白疫苗技术平台及宫颈癌疫苗产业化)
        Research on Common Co-construction Technology of Pharmaceutical Inhalation
        Preparations                                                                      1,900,000.00     900,000.00                0               0              0     2,800,000.00   Related to assets
      (开发区财政局拔款创业领军人才项目:药品吸入制剂共性共建技术的研究)
        Research and development of respiratory system drug and clinical research
        technology service platform project talent funding                                1,500,000.00              0                0               0              0     1,500,000.00   Related to assets
      (呼吸系统药物研发和临床研究技术服务平台项目人才经费)
        Science and technology help the economy key special projects
                                                                                           500,000.00               0                0               0              0      500,000.00    Related to assets
      (科技助力经济重点专项)
       City Service Development Special(市服务发展专项)                                  800,000.00               0                0               0              0      800,000.00    Related to assets
       Patent funding(专利资助)                                                                    0     200,000.00                0               0              0      200,000.00    Related to assets
      2020 Shanghai Professional Technology Platform Capacity Enhancement Project
                                                                                                     0    1,000,000.00               0               0              0     1,000,000.00   Related to assets
      (2020年度上海市专业技术平台能力提升项目立项)
       high-growth small and micro innovation enterprises(高成长小微科创企业)                      0     400,000.00                0               0              0      400,000.00    Related to assets
       Research and development subsidy for ω-3-Fish Oil Medium and Long Chain Fat
                                                                                           350,000.00               0                0               0              0      350,000.00    Related to assets
       Emulsion Injection(ω-3鱼油中/长链脂肪乳注射液研究开发补助)
      R&D and industrialization of innovative Ilaprazole Series
                                                                                         20,988,166.29              0                0    4,910,000.04              0    16,078,166.25   Related to assets
      (艾普拉唑系列创新药物研发及产业化)
      Research and development funds for new drug for Class I Treatment of Necrosis
        Factor in Human Tumour from Human Source                                          8,000,000.00              0                0               0              0     8,000,000.00 Related to income
      (I类治疗用人源化抗人肿瘤坏死因子α单克隆抗体新药研制资金)
        Strategic emerging industries in 2014 (sustained release microspheres)
                                                                                         16,700,000.00              0                0               0              0    16,700,000.00   Related to assets
      (2014年战略性新兴产业(缓释微球))
        Fund for industrialization of prolonged-action microsphere preparation
                                                                                         13,300,000.00              0                0      750,000.00              0    12,550,000.00   Related to assets
      (长效微球制剂的产业化款项)
       Construction project for industrialization of prolonged-action microsphere
                                                                                          7,024,025.85 15,329,800.00                 0    1,634,320.37              0    20,719,505.48   Related to assets
       preparation (phase I)(长效微球制剂产业化建设项目(一期工程))
       Pilot-scale enlargement and industrialization of prolonged-action injection
                                                                                          2,400,000.00              0                0    2,400,000.00              0               0    Related to assets
       microsphere products(长效注射微球产品的中试放大和产业化)
      Project subsidy from the Ministry of Industry and Information Technology
                                                                                          2,400,000.00              0                0               0              0     2,400,000.00   Related to assets
      (工业和信息化部项目补助款)
      Project subsidy from the Ministry of Industry and Information Technology
                                                                                          1,597,750.00              0                0      231,000.00              0     1,366,750.00   Related to assets
      (工业和信息化部项目补助款)
        Construction of Drug Conformity Evaluation Research Center Platform
                                                                                          1,200,000.10              0                0      159,999.96              0     1,040,000.14   Related to assets
      (药物一致性评价研究中心平台建设)
        R&D and Commercialisation of Mouse Nerve Growth Factor for Injection
                                                                                         50,606,036.20              0                0 10,560,089.27                0    40,045,946.93   Related to assets
      (注射用鼠神经生长因子研发及产业化)
        Demonstration project on the application of solar photovoltaic architecture
                                                                                          3,557,499.51              0                0    1,102,000.08              0     2,455,499.43   Related to assets
      (太阳能光电建筑应用示范项目)
       Subsidy for the Tender of Technology Upgrade Project for PVC Soft Bag Supported
                                                                                          3,111,850.32              0                0      408,365.76              0     2,703,484.56   Related to assets
       by Provincial Finance Departments(省财政支持技改招标项目补助金PVC软袋)
      Technical transformation project of Shenqi Fuzheng Injection with exible bag
                                                                                         19,500,000.02              0                0    3,823,529.40              0    15,676,470.62   Related to assets
      (软袋参芪扶正注射液技改项目)
        Provision for technology transformation funds and subsequent grants
                                                                                          6,589,119.08              0                0    1,129,563.36              0     5,459,555.72   Related to assets
      (技术改造资金拨款及事后补奖)




220
                                                                                                                                                                            Annual Report
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                                                                                                                              Amount
                                                                                                              Amount                           Amount
                                                                                        Balance at the                      charged to                                        Balance
                                                                                                         of additional                       charged to                                Related to assets/
 Liabilities                                                                               Beginning                    Non-operating                   Other changes       at the End
                                                                                                              grant for                  Other income                                  Related to income
                                                                                           of the Year                  income for the                                   of the Period
                                                                                                            the Period                   for the Period
                                                                                                                                Period
Provision for technology transformation funds and subsequent grants
                                                                                        10,648,600.33              0                0    3,288,929.52              0     7,359,670.81   Related to assets
(技术改造资金拨款及事后补奖)
 Electricity distribution transformer performance enhancement for energy-saving and
                                                                                          428,000.00               0                0       48,000.00              0      380,000.00    Related to assets
 emission reduction projects(节能减排项目配电变压器能效提升)
  R&D and industrialization team of chemical drug liquid preparation
                                                                                         1,000,000.00    1,008,000.00               0      473,166.56              0     1,534,833.44   Related to assets
(化药液体制剂研发与产业化团队)
  Innovation capacity building of technology center (antibody laboratory)
                                                                                         5,248,234.16              0                0      445,755.36              0     4,802,478.80   Related to assets
(技术中心创新能力建设(抗体药物实验室))
  Innovation capacity building of technology center (antibody laboratory)
                                                                                          241,769.82               0                0       75,330.36              0      166,439.46 Related to income
(技术中心创新能力建设(抗体药物实验室))
  Achievement transfer of blood screening (BCI) nucleic acid detection testing
                                                                                         6,000,000.00              0                0    2,038,717.56              0     3,961,282.44   Related to assets
(血液筛查(BCI)核酸检测试剂成果转化)
  Technological upgrading and transformation projects of workshop for acarbose
  (APIs for α-glucosidase inhibitor)                                                     571,428.64               0                0      107,142.84              0      464,285.80    Related to assets
(α-葡萄糖苷酶抑制剂类原料药阿卡波糖生产车间工艺升级技术改造项目)
 R&D and industrialization of Statins(降血脂他汀类药物的研发与产业化)                     60,000.36              0                0       29,999.88              0       30,000.48    Related to assets
  Scientic technology award and subsidy for technological innovative project
                                                                                          139,491.80               0                0      110,925.60              0       28,566.20    Related to assets
(科学技术奖及科技创新项目资助)
  Scientic technology award and subsidy for technological innovative project
                                                                                         3,400,000.00              0                0    1,200,000.00              0     2,200,000.00 Related to income
(科学技术奖及科技创新项目资助)
  Zhuhai industrial enterprise“cloud and platform”service coupons supporting funds
                                                                                          114,972.73               0                0       25,540.87              0       89,431.86 Related to income
(珠海市工业企业“云上平台”服务券支持资金)
 Commissioner workstation(特派员工作站)                                                 145,000.00               0                0       60,000.00              0       85,000.00    Related to assets
 Industrial revitalisation supporting funds(产业振兴扶持资金)                          3,603,500.01              0                0    1,158,000.00              0     2,445,500.01   Related to assets
  Phase IV clinical study of innovative drug Ilaprazole
                                                                                         8,210,800.00              0                0               0              0     8,210,800.00   Related to assets
(创新药物艾普拉唑IV期临床研究)
 Government grant for industrial transformation(工业转型政府扶持资金)                   508,333.67               0                0      199,999.92              0      308,333.75    Related to assets
 New industrialization development grant(新型工业化发展奖金)                           1,304,166.42    2,629,900.00               0      350,000.04              0     3,584,066.38   Related to assets
  Policy fund for leading industrial enterprises loan Interests
                                                                                          566,666.61               0                0      200,000.04              0      366,666.57    Related to assets
(工业龙头企业贷款贴息政策资金)
  Supporting funds for ve advantageous industrial clusters and one high-tech
  industry                                                                                400,000.16               0                0       99,999.96              0      300,000.20    Related to assets
(五优一新扶持资金)
 Subsidy for new R&D institution(新型研发机构补助)                                     2,000,000.00              0                0    2,000,000.00              0               0    Related to assets
  Zhuhai innovation and enterprising team and high-level talent enterprising project
  (paclitaxel micellar for injection)                                                    2,700,000.00    6,300,000.00               0               0    9,000,000.00              0    Related to assets
(珠海市创新创业团队和高层次人才创业项目(注射液紫杉醇胶束))
  Capital project for innovation and entrepreneurship team funding program
                                                                                         8,500,000.00    4,000,000.00               0               0              0    12,500,000.00   Related to assets
(创新创业团队资助计划资金项目)
  2020 Zhuhai City Innovation and Entrepreneurship Team(Nanocrystalline)
                                                                                                    0    1,500,000.00               0               0              0     1,500,000.00   Related to assets
(2020年度珠海市创新创业团队(纳米晶))
  Fund for R&D and industrialization of innovative Ilaprazole series
                                                                                         5,600,000.00              0                0               0              0                    Related to assets
(艾普拉唑系列创新药物研发及产业化项目资金)
Key projects of industrial core and key technologies of Zhuhai (Ryanodex)
                                                                                         3,000,000.00              0                0               0              0                    Related to assets
(珠海市产业核心和关键技术攻关方向项目(丹曲林钠))
  Data-driven industrial chain collaboration platform demonstration project
                                                                                                    0    3,650,000.00               0               0              0     3,650,000.00   Related to assets
(数据驱动的产业链协同平台示范项目)
  Fund for key projects of industrial core and key technologies of Zhuhai (2nd batch)
                                                                                         2,000,000.00              0                0               0              0     2,000,000.00   Related to assets
(珠海市产业核心和关键技术攻关方向项目资金(第二批))
  Innovative drug of Ilaprazole sodium for injection
                                                                                         2,400,000.00              0                0               0              0     2,400,000.00   Related to assets
(创新药注射用艾普拉唑钠针剂)




                                                                                                                                                                                                    221
                                                                                                                                      Amount
                                                                                                                      Amount                           Amount
                                                                                                Balance at the                      charged to                                        Balance
                                                                                                                 of additional                       charged to                                Related to assets/
       Liabilities                                                                                 Beginning                    Non-operating                   Other changes       at the End
                                                                                                                      grant for                  Other income                                  Related to income
                                                                                                   of the Year                  income for the                                   of the Period
                                                                                                                    the Period                   for the Period
                                                                                                                                        Period
        Technological transformation projects of new Cefuroxime
                                                                                                 1,533,100.00              0                0               0              0     1,533,100.00   Related to assets
      (新型头孢粉针剂技术改造项目)
        Internet benchmarking project for advanced drug Manufacturing
                                                                                                  765,000.00               0                0       90,000.00              0      675,000.00    Related to assets
      (先进药品制造互联网标杆项目)
       Cleaner Production Audit Project(清洁生产审核项目)                                       190,000.04               0                0        9,999.96              0      180,000.08    Related to assets
       Green factory(绿色工厂)                                                                 1,261,666.67              0                0      129,999.96              0     1,131,666.71   Related to assets
       HCG project construction(HCG项目建设)                                                   3,783,485.81              0                0      395,649.97              0     3,387,835.84   Related to assets
       Sewage treatment system upgrade project(污水处理系统升级改造项目)                          72,269.96              0                0        8,030.04              0       64,239.92    Related to assets
       R&D and industrialization of Recombinant Human Chorionic Gonadotropin for
                                                                                                 1,287,500.00              0                0      150,000.00              0     1,137,500.00   Related to assets
       Injection(注射用重组人绒促性素研发及产业化)
        Subsidies for online monitoring equipment and installations of coalred boilers
                                                                                                  105,000.00               0                0       22,500.00              0       82,500.00    Related to assets
      (燃煤锅炉在线监控设备装置补助资金)
       Funds for joint R&D and industrialization of integrated platform for molecular
                                                                                                 1,550,000.00              0                0    1,368,367.88              0      181,632.12    Related to assets
       diagnostics(集成一体化分子诊断平台的合作研发及产业化资金)
        Project supporting fund for the rst batch of special funds for scientic and
        technological innovation in 2019                                                          850,000.00               0                0      250,000.00              0      600,000.00    Related to assets
      (2019年度第一批科技创新专项资金立项配套资助)
       Provincial industrial innovation (provincial enterprise technology center) project in
                                                                                                 1,403,733.33              0                0      357,200.00              0     1,046,533.33   Related to assets
       2019(2019年省产业创新(省级企业技术中心)项目)
      Guangdong Province Science and Technology Department special emergency fund
        for scientic and technological research on prevention and control of COVID-19             350,000.00               0                0      350,000.00              0               0    Related to assets
      (广东省科学技术厅汇防控新型冠状病毒感染科技攻关应急专项款)
       Zhuhai Financial Bureau cum COVID-19 emergency technology special emergency
                                                                                                  250,000.00               0                0      250,000.00              0               0    Related to assets
       fund(珠海市财政局汇新冠应急科技攻关专项款)
        China Postdoctoral Science Foundation subsidy funds
                                                                                                  160,000.00               0                0               0       80,000.00      80,000.00 Related to income
      (中国博士后科学基金会资助经费)
       Pre-appropriation of special grants for industrialization of diagnostic reagents for
                                                                                                 4,601,200.00              0                0      484,784.35              0     4,116,415.65   Related to assets
       COVID-19(新型冠状病毒检测试剂产业化项目补助金预拨)
        Xiangzhou District equipment purchase subsidy supporting funds (special funds for
        prevention and control of pandemic)                                                         13,555.75              0                0        2,088.50              0        11,467.25   Related to assets
      (香洲区购置设备补贴扶持资金(疫情防控专项资金))
       Zhuhai innovation and enterprising team and high-level talent enterprising project
                                                                                                12,000,000.00              0                0               0              0    12,000,000.00   Related to assets
       Phase I funds(珠海市创新创业团队和高层次人才创业项目首期资金)
       Overall relocation and deployment expansion project(整体搬迁调迁扩建项目)              20,000,000.00              0                0               0              0    20,000,000.00   Related to assets
        Environmental protection bureau RTO project special funds
                                                                                                  200,000.00               0                0       20,000.04              0      179,999.96    Related to assets
      (环保局RTO项目资金)
       Structure-eciency optimization of marine microorganisms and evaluation of
                                                                                                            0     324,673.61                0       12,307.34              0      312,366.27 Related to income
       antitumor activity(海洋微生物构效优化与抗肿瘤活性评价)
       Total                                                                                   467,562,770.49 53,936,373.61                 0 60,424,091.70 27,531,700.00 433,543,352.40


      Other descriptions:
      □ Applicable √ N/A

36. Other non-current liabilities
      √ Applicable □ N/A
                                                                                                                                                                            Unit: Yuan Currency: RMB
                                                                                                                               Balance at the End                         Balance at the Beginning
       Item
                                                                                                                                    of the Period                                     of the Period
       The overall relocation and expansion project of Sichuan
                                                                                                                                      78,000,000.00                                      78,000,000.00
       Guangda Pharmaceutical Manufacturing
       Total                                                                                                                          78,000,000.00                                      78,000,000.00


222
                                                                                                                           Annual Report
                                                                                                                                   2021


37. Share capital
    √ Applicable □ N/A
                                                                                                                      Unit: Yuan Currency: RMB
                                                         Balance at the            Changes for the Period (+ -)                     Balance at
                                                          Beginning of Issuance of Reserve fund                                     the End of
                                                                                                        Others        Sub-total
                                                            the Period new shares    capitalised                                    the Period
    I. Tradable shares subject to selling restrictions
    1. Domestic legal person shares                                 0            0                 0             0           0              0
    2. Domestic natural person shares                               0            0                 0             0           0              0
    3. Overseas legal person shares                                 0            0                 0             0           0              0
    Tradable shares subject to selling restrictions
                                                                    0            0                 0             0           0              0
    in aggregate
    II. Tradable shares
    1. Ordinary shares denominated in RMB                1,952,780,764 10,082,440                  0 -55,135,296 -45,052,856 1,907,727,908
    2.Domestically listed foreign shares                            0            0                 0           0           0             0
    Tradable shares in aggregate                         1,952,780,764 10,082,440                  0 -55,135,296 -45,052,856 1,907,727,908
    Total number of shares                               1,952,780,764 10,082,440                  0 -55,135,296 -45,052,856 1,907,727,908


    Other descriptions: The reduced registered capical during the Reporting Period is due to the cancellation of the repurased
    shares.


38. Capital reserve
    √ Applicable □ N/A
                                                                                                                      Unit: Yuan Currency: RMB
                                                 Balance at the Beginning       Increase for the       Decrease for the   Balance at the End
    Item
                                                             of the Period               Period                 Period         of the Period
    Capital premium (Share premium)                       2,531,019,936.35      369,115,622.89         747,275,331.40       2,152,860,227.84
    Other capital reserve                                     2,268,737.93      114,769,391.67            4,541,045.52        112,497,084.08
    Total                                                 2,533,288,674.28      483,885,014.56         751,816,376.92       2,265,357,311.92


    Other descriptions, including changes for the current period and reasons therefor:

    Reasons for increase in chaiptal premium: 1) 10,082,440 shares of the Company's stock options were exercised, increasing
    the capital premium by RMB 72,493,116.59, and the corresponding accrued share incentive fee of RMB 1,457,178.93 was
    transferred from other capital reserves to the capital premium; 2) The Company's subsidiary Livzon's stock options are
    exercised, according to the shareholding ratio of the Company, the corresponding increase in the share capital premium of
    88,109,304.98 yuan, and the corresponding accrued equity incentive expenses of 3,083,866.59 yuan are transferred from other
    capital reserves to the share capital premium; 3) After the stock options are exercised,the difference between the pre-taxable
    expenses and the accrued expenses will reduce the income tax payable by RMB 13,609,184.27, and the share capital premium
    will be increased accordingly; 4) Since the overseas financing of the subsidiary Livzon is transferred to the Mainland China
    and thus the reduced registered capical of the subsidiaries are not in the same proportion. Correspondingly, the capital premium
    is increased by RMB 190,362,971.53 for the difference between the net assets of the subsidiaries owned by the Company
    before and after the reduction of share capital.

    The decrease in share capital premium of RMB 747,275,331.4 for the period was due to the cancellation of shares repurchased
    by the Company and the subsidiary Livzon.Group.

    Reasons for changes in Other capital reserves: 1) The Company and its subsidiary Livzon Group provided equity incentive
    expenses of RMB 11,652,295.42; 2) The subsidiary Livzon Group's equity method accounting units increased capital in
    different proportions, resulting in changes in the Company's shareholding ratio and changes in other equity instrument
    investment;Thus the capital reserve increased by RMB 35,846,098.47. 3) The exercise of the stock options of the incentive


                                                                                                                                          223
      plan and and repurchase of the subsidiary Livzon Group lead to changes in the Company's shareholding ratio and changes in
      other equity instrument investment; thus the capital reserve decreased by RMB 55,295,829.27; 4) the capital reserve of RMB
      11,975,168.51 transferred to prot and loss asThe Company disposed of the subsidiaries;

      Other capital reserves decreased as the equity incentive expenses of RMB 4,541,045.52 was transferred to the share capital
      premium


39. Treasury shares
      √ Applicable □ N/A
                                                                                                                                                           Unit: Yuan Currency: RMB
                                                                                    Balance at the                                                                      Balance at the
                                                                                                              Increase for the           Decrease for the
      Item                                                                           Beginning of                                                                              End of
                                                                                                                       Period                     Period
                                                                                       the Period                                                                          the Period
      Repurchase of A Shares due to Share Ownership
                                                                                  253,637,154.50                                 0.00       30,992,700.00             222,644,454.50
      Scheme and Share Options Incentive Scheme
      Repurchase of shares to be cancelled                                                        0.00        699,900,526.87              699,900,526.87                              0.00
      Total                                                                       253,637,154.50              699,900,526.87              730,893,226.87              222,644,454.50


      Other descriptions, including changes for the current period and reasons therefor:

      The reason for decreases in the ending balances of Repurchase of A Shares due to Share Ownership Scheme and Share Options
      Incentive Scheme is that the shares repurchased transferred to the designated special account of the Share Ownership Scheme
      The increase of treasury shares during the period represented: The Company repurchased 55,135,296 shares totally through
      centralized bidding transactions by the Company. The decrease in treasury shares during the Year: the cancellation of
      repurchased shares.


40. Other comprehensive income
      √ Applicable □ N/A
                                                                                                                                                           Unit: Yuan Currency: RMB
                                                                                                                For the Period
                                                                                          Less: amount recognised
                                                      Balance at the         Amount         in other comprehensive                       Attributable to      Attributable     Balance at the
                                                                                                                             Less:
      Item                                             Beginning of    incurred before      income in the Previous                           the parent       to minority         End of the
                                                                                                                       income tax
                                                         The Period        income tax    Period transferred to prot                           company       interests after           Period
                                                                                                                         expenses
                                                                        for the Period or loss or retained earnings                            after tax               tax
                                                                                                     for the Period
      I. Other comprehensive income not to be re-
                                                     180,616,463.38    43,382,751.21               171,926,789.47 2,196,770.08           -78,059,481.21    -52,681,327.13     102,556,982.18
      classied into prot or loss
      Of which: Other comprehensive income not
      to be reclassied into prot or loss under                 0.00    14,820,196.44                          0.00               0.00     6,658,847.65      8,161,348.794       6,658,847.65
      equity method
      Change in fair value of other investments in
                                                     180,616,463.38    28,562,554.77               171,926,789.47 2,196,770.08           -84,718,328.85    -60,842,675.92      95,898,134.53
      equity instruments
      II. Other comprehensive income to be
                                                     -64,315,904.10    -46,945,392.92                         0.00               0.00    -32,853,532.10    -14,091,860.81     -97,169,436.20
      reclassied into prot or loss
      Of which:Other comprehensive income to
      be reclassied into prot or loss under the           51,589.71       -30,268.270                         0.00               0.00        -13,599.80       -16,668.468          37,989.91
      equity method
       Translation dierences of nancial
                                                     -64,367,493.82 -46,915,124.650                           0.00               0.00    -32,839,932.30 -14,075,192.346       -97,207,426.12
      statements denominated in foreign currency
      Total of other comprehensive income            116,300,559.28     -3,562,641.71              171,926,789.47 2,196,770.08          -110,913,013.31    -66,773,187.94       5,387,545.97



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41. Surplus reserve
    √ Applicable □ N/A
                                                                                                                Unit: Yuan Currency: RMB
                                               Balance at the                                                            Balance at the
                                                                        Increase for          Decrease for
    Item                                        Beginning of                                                                    End of
                                                                          the Period            the Period
                                                  the Period                                                                the Period
    Statutory surplus reserve                474,626,867.82          124,879,713.89                      0.00          599,506,581.71
    Discretionary surplus reserve              40,210,642.44                    0.00                     0.00            40,210,642.44
    Reserve funds                                1,103,954.93                   0.00                     0.00             1,103,954.93
    Total                                    515,941,465.19          124,879,713.89                      0.00          640,821,179.08


42. Retained earnings
    √ Applicable □ N/A
                                                                                                                Unit: Yuan Currency: RMB
    Item                                                                                For the Period          For the Previous Period
    Retained earnings for the end of Last Period before adjustment                 6,231,451,582.26                   5,443,313,968.30
    Adjustment for total retained earnings as at the beginning of the
                                                                                                 0.00                             0.00
    Period (+ for increase and – for decrease)
    Retained earnings at the beginning of the Period after adjustment              6,231,451,582.26                   5,443,313,968.30
    Add: Net earnings attributable to the owners of the parent
                                                                                   1,328,499,432.05                   1,120,439,799.25
    company for the Period
    Gain on disposal of other equity investments                                        77,248,253.85                    38,047,665.80
    Less: Appropriation to statutory surplus reserve                                   124,879,713.89                    61,926,327.89
    Appropriation to discretionary surplus reserve                                               0.00                             0.00
    Dividends payable to ordinary shares                                               288,675,388.05                  308,423,523.20
    Dividends of ordinary shares capitalised                                                     0.00                             0.00
    Retained earnings at the end of the Period                                     7,223,644,166.22                   6,231,451,582.26


    Descriptions of appropriation of prots
                                                                                                                Unit: Yuan Currency: RMB
    Item                                                                                         2020                             2019
    Dividends:
    Final dividends in respect of the year 2020 paid during the year (Note 2)          288,675,388.05
    Final dividends in respect of the year 2019 paid during the year (Note 3)                                          308,423,523.20
    Dividends proposed after the balance sheet date:
    Final dividends proposed for the year 2021 (Note 1)                                          0.00
    Final dividends proposed for the year 2020 (Note 2)                                                                288,675,388.05


    Note 1: On 29 March 2022, the Company convened the 9th meeting of the 8th Session of the Board, at which the Company's
            Prot Distribution Proposal for 2021 was approved: a cash dividend of RMB 1.50 (tax inclusive) will be distributed to
            all shareholders for every 10 shares, based on the total share capital of the Company on the equity registration date as
            determined for implementation of the Company's prot distribution plan for 2021, minus the total number of shares in
            the Company's special securities account for repurchase, with the remaining undistributed prots to be carried forward
            to the following year.

    Note 2: According to the 2020 Annual Profit Distribution Plan approved at 2020 Annual General Meeting of Shareholders
            on 21 May 2021 of the Company, it is expected to distribute cash dividend of RMB0.15 for every share to all
            Shareholders of the Company. And the total cash distributed is RMB288,675,388.05 based on 1,924,502,587 shares,
            which calculated by the 1,958,593,217 issued shares registered in the Shanghai Branch of China Securities Depository
            and Clearing Co., Ltd on 24 June of 2021after deducting the 34,090,630 shares repurchased in the repurchase account.

                                                                                                                                    225
      Note 3: According to the 2019 Annual Profit Distribution Plan approved at 2019 Annual General Meeting of Shareholders
              on 29 May 2020 of the Company, it is expected to distribute cash dividend of RMB0.16 for every share to all
              Shareholders of the Company. And the total cash distributed is RMB 308,423,523.20 based on 1,927,647,020 shares,
              which calculated by the 1,947,537,633 issued shares registered in the Shanghai Branch of China Securities Depository
              and Clearing Co., Ltd on 2 July of 2020 after deducting the 19,890,613 shares repurchased in the repurchase account.


43. Operating income and operating cost
 (1) Operating income and operating cost
     √ Applicable □ N/A
                                                                                                          Unit: Yuan Currency: RMB
                                                             For the Period                        For the Previous Period
      Item
                                                           Income                   Cost             Income                  Cost
      Principal activities                     15,746,624,848.53      5,604,702,296.12     13,445,875,833.84    4,821,005,051.41
      Other activities                            157,063,418.06        111,591,591.46         75,729,934.36       53,181,846.64
      Total                                    15,903,688,266.59      5,716,293,887.58     13,521,605,768.20    4,874,186,898.05


    Other descriptions:
    Breakdown information of principal activities income
 ① Breakdown by product types


                                                       January to December 2021                   January to December 2020
      Item
                                                           Income                  Cost              Income                  Cost
      Chemical APIs and Intermediates           4,690,255,375.73     3,184,889,165.53       3,934,784,153.44    2,625,972,440.71
      Chemical drug preparation products        9,102,675,799.95     1,769,561,792.01       6,699,175,307.66    1,362,807,966.99
      Traditional Chinese drug preparation
                                                1,109,344,037.45       295,328,306.33       1,247,075,910.10      339,295,382.97
      products
      Health care products                        115,164,422.30        33,652,500.02        145,411,197.65        45,682,412.00
      Diagnostic reagents and equipment           723,917,736.81       319,168,131.72       1,382,748,085.32      414,163,893.55
      Others                                          254,849.67              328,336.21      30,387,281.00        30,330,859.23
      Industry and Commerce Subtotal           15,741,612,221.92     5,602,928,231.82      13,439,581,935.17    4,818,252,955.45
      Service industry                               5,012,626.61         1,774,064.30          6,293,898.67        2,752,095.96
      Total                                    15,746,624,848.53     5,604,702,296.12      13,445,875,833.84    4,821,005,051.41


 ② Breakdown by major operating regions


                                                       January to December 2021                   January to December 2020
      Item
                                                           Income                  Cost              Income                  Cost
      Domestic                                 13,175,044,906.28     3,837,751,076.40      10,785,410,799.31    3,182,220,956.99
      Overseas                                  2,571,579,942.25     1,766,951,219.72       2,660,465,034.53    1,638,784,094.42
      Total                                    15,746,624,848.53     5,604,702,296.12      13,445,875,833.84    4,821,005,051.41


 ③ Breakdown by time of income recognition


                                                       January to December 2021                   January to December 2020
      Item
                                                           Income                  Cost              Income                  Cost
      Commodities (recognised at a point
                                               15,746,624,848.53     5,604,702,296.12      13,445,875,833.84    4,821,005,051.41
      of time)
      Total                                    15,746,624,848.53     5,604,702,296.12      13,445,875,833.84    4,821,005,051.41



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④ Operating income of top ve customers


                                                      Total operating income of the top          Proportion of main business income
    Period
                                                                         ve customers                         in the same period (%)
    January to December 2021                                          1,372,032,796.69                                         8.71
    January to December 2020                                          1,005,534,593.73                                         7.48


⑤ Breakdown of non-core businesses


                                                         January to December 2021                     January to December 2020
    Item
                                                          Income                   Cost                Income                  Cost
    Selling raw materials                           50,440,716.79        40,772,550.07           27,671,720.97        21,411,470.46
    Processing charges                               6,794,908.37          1,660,944.94           1,069,292.89           388,143.68
    Lease                                            9,381,937.42            112,497.34          14,606,830.90         6,646,206.06
    Inspection fees                                           0.00                  0.00            213,284.91                 0.00
    Power and Utilities                             11,855,332.16         11,464,416.78          15,067,776.06        14,223,405.64
    Others                                          78,590,523.32        57,581,182.33           17,101,028.63        10,512,620.80
    Total                                         157,063,418.06        111,591,591.46           75,729,934.36        53,181,846.64


44. Taxes and surcharges
    √ Applicable □ N/A
                                                                                                            Unit: Yuan Currency: RMB
    Item                                                                  For the Period                     For the Previous Period
    Urban maintenance and construction tax                               78,915,243.23                                71,147,999.02
    Education surcharges                                                 57,919,345.89                                53,550,431.82
    Property tax                                                         22,448,547.60                                20,276,839.64
    Land use tax                                                           9,853,262.81                               10,150,547.58
    Stamp duty and others                                                13,680,250.49                                 7,516,286.05
    Total                                                               182,816,650.02                              162,642,104.11


    Other descriptions:
    The bases of calculations for major taxes and surcharges are set out in Note IV. Taxation.


45. Selling expenses
    √ Applicable □ N/A
                                                                                                            Unit: Yuan Currency: RMB
    Item                                                                  For the Period                     For the Previous Period
    Marketing and promotional expenses                                4,477,764,584.15                             3,476,022,898.97
    Sta salaries                                                        397,170,070.40                              324,928,316.74
    Oce, entertainment and travelling expenses                            65,297,664.11                               58,624,951.47
    Business meeting expenses                                            23,554,731.43                                15,451,969.22
    Others                                                               63,025,095.32                                65,308,968.89
    Total                                                             5,026,812,145.41                             3,940,337,105.29




                                                                                                                                 227
46. Administrative expenses
      √ Applicable □ N/A
                                                                                           Unit: Yuan Currency: RMB
      Item                                                               For the Period    For the Previous Period
      Sta salaries                                                      458,139,486.90            419,321,625.18
      Depreciation and amortisation                                     118,237,699.36              99,360,656.37
      Loss on suspension of operations                                   67,730,993.25            102,477,386.51
      Share incentive expenses                                           27,642,491.39              35,587,152.92
      Advisory, consultancy and information disclosure fees              28,176,640.22              26,248,855.50
      Quality project expenses                                           46,075,518.11              51,118,220.20
      Oce, entertainment and travelling expenses                         60,231,705.78              71,244,309.60
      Repair of utilities, transportation and miscellaneous expenses     41,571,843.51              33,397,279.98
      Recruitment and sta training expenses                              10,648,299.29              12,434,260.13
      Others                                                             80,798,766.52              99,637,816.08
      Total                                                             939,253,444.33            950,827,562.47


47. R&D expenses
      √ Applicable □ N/A
                                                                                           Unit: Yuan Currency: RMB
      Item                                                               For the Period    For the Previous Period
      Material costs                                                    289,853,404.42            246,044,210.79
      Sta salaries                                                      399,459,964.18            278,021,637.62
      Share incentive expenses                                             6,884,591.21                704,431.47
      Testing fees                                                      434,694,547.02            350,009,783.09
      Depreciation and amortisation                                     130,493,088.54              89,801,938.18
      Acquired Technology                                                  7,318,927.47             19,773,674.13
      Others                                                            128,426,750.49              87,356,306.67
      Total                                                            1,397,131,273.33          1,071,711,981.95


48. Finance expenses
      √ Applicable □ N/A
                                                                                           Unit: Yuan Currency: RMB
      Item                                                                For the Period   For the Previous Period
      Interest expenses                                                   90,253,042.69             35,689,153.09
      Interest income                                                   -191,964,051.82           -203,479,591.12
      Exchange (gains)/losses                                              2,737,152.59             62,347,543.47
      Commission charges and others                                        6,079,104.82              6,557,073.98
      Total                                                              -92,894,751.72            -98,885,820.58




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49. Other income
    √ Applicable □ N/A
                                                                                                        Unit: Yuan Currency: RMB
                                                                                                              Related to assets/
    Item                                             For the Period        For the Previous Period
                                                                                                              Related to income
    Government grants                                59,110,913.13                  37,465,591.29              Related to assets
    Government grants                              186,224,227.56                  208,797,326.66             Related to income
    Tax withholding commission charges                2,011,794.27                   2,038,723.31
    Extra tax deductions for tax refunds                       0.00                       23,224.44
    Total                                          247,346,934.96                  248,324,865.70


    Other descriptions:
    For specic information on government grants, please refer to Note V. 62. Government grants for details.

50. Investment income
    √ Applicable □ N/A
                                                                                                        Unit: Yuan Currency: RMB
    Item                                                                            For the Period       For the Previous Period
    Long-term equity investments income under equity method                         10,281,021.59                 17,271,121.06
    Investment income from disposal of long-term equity investments                 -9,552,139.31               103,699,130.93
    Investment income from nancial assets held for trading during the
                                                                                      2,421,216.08                   337,875.68
    holding period
    Dividend income from other equity instrument investments                        37,114,395.95                 23,065,993.55
    Investment income from disposal of nancial assets held for trading              31,616,770.34                 30,282,438.65
    Income generated from revaluation of remaining equity measured at
                                                                                               0.00                7,958,514.22
    fair value upon loss of control
    Others                                                                                     0.00                 -298,617.11
    Total                                                                           71,881,264.65               182,316,456.98


51. Gains from changes in fair value
    √ Applicable □ N/A
                                                                                                        Unit: Yuan Currency: RMB
    Sources of gains from changes in fair value                          For the Period                  For the Previous Period
    Financial assets held for trading                                    -23,363,035.92                           10,204,016.16
    Of which: Debt instrument investments                                     30,410.89                               14,481.37
    Equity instrument investments                                        -17,702,179.18                              152,493.76
    Derivative nancial assets                                             -5,691,267.63                           10,037,041.03
    Financial liabilities held for trading                                 -143,090.17                                13,703.93
    Of which: Derivative nancial liabilities                               -143,090.17                                13,703.93
    Total                                                                -23,506,126.09                           10,217,720.09


52. Credit impairment loss
    √ Applicable □ N/A
                                                                                                        Unit: Yuan Currency: RMB
    Item                                                                 For the Period                  For the Previous Period
    Bad debt loss of bills receivables                                            0.00                              -431,000.00
    Bad debt loss of accounts receivables                                -9,189,454.14                            -5,248,048.75
    Bad debt loss of other receivables                                    1,165,341.94                            -1,159,898.79
    Total                                                                -8,024,112.20                            -6,838,947.54



                                                                                                                            229
53. Asset impairment losses
      √ Applicable □ N/A
                                                                                                    Unit: Yuan Currency: RMB
      Item                                                                For the Period             For the Previous Period
      I. Losses on bad debts                                                        0.00                                0.00
      II. Losses on decline in value of inventories and on
                                                                         -61,759,256.42                      -76,606,295.55
      impairment of contract performance costs
      III. Losses on impairment of long-term equity investments                     0.00                                0.00
      IV. Losses on impairment of property                                         0.00                                0.00
      V. Losses on impairment of xed assets                               -1,191,722.30                       -3,100,286.17
      VI. Losses on impairment of project materials                                 0.00                                0.00
      VII. Losses on impairment of construction in progress                         0.00                                0.00
      VIII. Losses on impairment of bearer biological assets                        0.00                                0.00
      IX. Losses on impairment on oil and gas assets                                0.00                               0.00
      X. Losses on impairment of intangible assets                                  0.00                      -1,080,293.98
      XI. Losses on impairment of goodwill                                          0.00                                0.00
      XII. Others                                                                   0.00                                0.00
      Total                                                              -62,950,978.72                      -80,786,875.70


54. Gains on disposal of assets
      √ Applicable □ N/A
                                                                                                    Unit: Yuan Currency: RMB
      Item                                                                For the Period             For the Previous Period
      Gains on disposal of xed assets (“-”represents losses)             6,780,989.95                       -1,064,564.68
      Gains on disposal of Intangible assets (“-”represents losses)     17,263,196.60                                 0.00
      Total                                                               24,044,186.55                       -1,064,564.68


55. Non-operating income
      √ Applicable □ N/A
                                                                                                    Unit: Yuan Currency: RMB
                                                         For the        For the Previous   Amount charged to non-recurring
      Item
                                                         Period                   Period    gains or losses during the Period
      Gains on destruction or retirement of
                                                      631,652.20             111,294.41                          631,652.20
      non-current assets
      Income from scraps                           3,106,514.85            1,048,932.53                        3,106,514.85
      Compensation income                             890,504.89           2,473,510.35                          890,504.89
      Waiver of payables                              891,816.68           4,165,953.70                          891,816.68
      Others                                       3,121,342.24            2,632,556.61                        3,121,342.24
      Total                                        8,641,830.86           10,432,247.60                        8,641,830.86


      Government grants included in current prot or loss
      □ Applicable √ N/A




230
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56. Non-operating expenses
    √ Applicable □ N/A
                                                                                                         Unit: Yuan Currency: RMB
                                                        For the        For the Previous         Amount charged to non-recurring
     Item
                                                        Period                   Period          gains or losses during the Period
     Total losses on disposal of
                                                  7,057,428.39             6,125,145.64                             7,057,428.39
     non-current assets
     External donation                          29,101,247.20            22,163,382.60                             29,101,247.20
     Others                                       3,220,598.10             4,938,235.61                             3,220,598.10
     Total                                      39,379,273.69            33,226,763.85                             39,379,273.69


57. Income tax expenses
(1) Table of income tax expenses
    √ Applicable □ N/A
                                                                                                         Unit: Yuan Currency: RMB
     Item                                                                 For the Period                  For the Previous Period
     Current income tax                                                 375,813,164.01                            455,645,093.01
     Deferred income tax                                                -36,332,858.72                            -83,951,512.84
     Total                                                              339,480,305.29                            371,693,580.17


(2) Reconciliation of income tax expenses to the accounting prot
    √ Applicable □ N/A
                                                                                                         Unit: Yuan Currency: RMB
     Item                                                                                                          For the Period
     Total prot                                                                                                 2,952,329,343.96
     Income tax expenses calculated at legal/applicable tax rate                                                  738,082,335.99
     Eect of dierent tax rates applicable to subsidiaries                                                            -157,284.13
     Eect of tax reduction and exemption                                                                         -461,501,254.72
     Eect of non-deductible costs, expenses and losses                                                             11,222,334.85
     Eect of deductible tax losses for which no deferred tax assets were recognised in prior periods               -1,262,016.75
     Eect of deductible tax losses or deductible temporary dierences for which no deferred tax asset
                                                                                                                   91,064,540.85
     was recognised in the current period
     Others                                                                                                       -37,968,350.80
     Income tax expenses                                                                                          339,480,305.29


    Other descriptions:
    □ Applicable √ N/A




                                                                                                                              231
58. Items in the cash flow statement
(1). Cash received relating to other operating activities
     √ Applicable □ N/A
                                                                                Unit: Yuan Currency: RMB
      Item                                                    For the Period    For the Previous Period
      Government grants                                      231,492,540.63            284,761,193.77
      Interest income                                        177,822,721.68            204,437,373.98
      Recovery of employee loans                               8,237,323.25               7,821,420.99
      Deposits under guarantee                                75,737,734.89              65,972,530.31
      Indemnity received                                          83,043.02               2,450,218.35
      Movements in capital and others                         51,664,073.17              89,773,459.35
      Total                                                  545,037,436.64            655,216,196.75


(2). Cash paid relating to other operating activities
     √ Applicable □ N/A
                                                                                Unit: Yuan Currency: RMB
      Item                                                    For the Period    For the Previous Period
      Oce Expenses                                            98,749,129.18              71,351,485.02
      Travel expenses                                         69,905,127.66              70,653,292.94
      Business entertainment expense                          84,266,002.56              80,329,323.97
      Freight expenses                                       107,473,996.66              84,344,464.94
      advertising fee                                           3,789,481.18             10,191,855.40
      Conference fees                                         34,011,851.22              34,126,734.10
      Agency and consulting services Fees                     87,616,669.78              39,464,688.93
      R&D expenses                                           756,535,241.25            621,409,966.49
      Bank charges                                              5,874,566.03              6,557,073.98
      Reserves                                                  1,008,235.84             24,280,755.52
      Promotion Fees                                        4,788,794,823.81          3,537,165,014.07
      Letter of credit and bank acceptance deposit            33,459,360.54               2,943,454.22
      Other Expenses paid and current payments               214,400,075.57            301,474,163.25
      Total                                                 6,285,884,561.28          4,884,292,272.83


(3). Cash received relating to other investing activities
     √ Applicable □ N/A
                                                                                Unit: Yuan Currency: RMB
      Item                                                     For the Period   For the Previous Period
      Structured Deposits and Term Deposits                   100,000,000.00             33,000,000.00
      Deposits under guarantee                                 12,557,736.54                450,000.00
      Insurance claims                                                  0.00             19,828,856.24
      Compensation for demolition                                       0.00              8,000,000.00
      Payments received due to bankruptcy and
                                                                1,013,650.67                      0.00
      liquidation of Huaxia Securities Co., Ltd.
      Others                                                        2,700.00                229,160.14
      Total                                                   113,574,087.21             61,508,016.38




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(4). Cash paid relating to other investing activities
     √ Applicable □ N/A
                                                                                Unit: Yuan Currency: RMB
     Item                                                      For the Period   For the Previous Period
     Structured Deposits and Term Deposits                     50,000,000.00                      0.00
     Deposits under guarantee                                     235,000.00              8,846,941.28
     Foreign exchange forward contract losses                   2,831,260.72              3,564,544.29
     Others                                                         3,779.69                179,618.71
     Total                                                     53,070,040.41             12,591,104.28


(5). Cash received relating to other nancing activities
     √ Applicable □ N/A
                                                                                Unit: Yuan Currency: RMB
     Item                                                      For the Period   For the Previous Period
     Equity Transfer fee paid to Guosen Securities
                                                               30,992,700.00                      0.00
     Employee Stock Ownership Plan Account
     Collection and advance payment of individual
                                                                 6,859,477.42             2,778,643.64
     income tax
     Total                                                     37,852,177.42              2,778,643.64


(6). Cash paid relating to other nancing activities
     √ Applicable □ N/A
                                                                                Unit: Yuan Currency: RMB
     Item                                                      For the Period   For the Previous Period
     Repurchase of shares                                     938,084,088.14           503,698,567.66
     Capital reduction in minority interests in subsidiary    324,225,000.00                      0.00
     Rental                                                    27,862,261.10                      0.00
     Collection and advance payment of individual
                                                                 1,716,145.57                64,678.67
     income tax
     Dividend handling fee                                        152,691.48                      0.00
     Total                                                   1,292,040,186.29          503,763,246.33




                                                                                                    233
59. Supplemental information to cash flow statement
 (1) Supplemental information to cash ow statement
     √ Applicable □ N/A
                                                                                                          Unit: Yuan Currency: RMB
                                                                                                                 For the Previous
      Supplemental information                                                               For the Period
                                                                                                                           Period
      1. Reconciliation from net prot to cash ow from operating activities:
      Net prot                                                                             2,612,849,038.67     2,578,466,495.34
      Add: Asset impairment loss                                                             62,950,978.72         80,786,875.70
      Credit impairment loss                                                                   8,024,112.20         6,838,947.54
      Depreciation of xed assets, depletion of oil and gas assets, depreciation of
                                                                                            540,627,410.92       512,674,285.79
      bearer biological assets
      Amortisation of use of right assets                                                    26,000,791.57                  0.00
      Amortisation of intangible assets                                                      53,826,067.53         34,235,699.61
      Amortisation of long-term prepaid expenses                                             43,989,121.05         39,277,350.86
      Losses on disposal of xed assets, intangible assets and other long-term
                                                                                             -24,044,186.55         1,064,564.68
      assets (gain is indicated by“-”)
      Losses on retirement of xed assets (gain is indicated by“-”)                           6,425,776.19         6,013,851.23
      Losses on changes in fair values (gain is indicated by“-”)                           23,506,126.09        -10,217,720.09
      Financial expenses (gain is indicated by“-”)                                        100,946,504.76         77,412,457.94
      Investment losses (gain is indicated by“-”)                                         -71,881,264.65       -182,316,456.98
      Decrease in deferred tax assets (increase is indicated by“-”)                        -75,082,337.68       -75,956,091.84
      Increase in deferred tax liabilities (decrease is indicated by“-”)                    28,755,973.72        -7,995,421.00
      Decrease in inventories (increase is indicated by“-”)                               -306,334,662.14      -384,205,022.18
      Decrease in receivables from operating activities (increase is indicated by“-”)   -1,593,686,129.41      -647,413,039.05
      Increase in payables from operating activities (decrease is indicated by“-”)       1,036,581,635.58      963,799,874.60
      Others                                                                                 89,634,088.67         32,532,940.09
      Net cash ow from operating activities                                                2,563,089,045.24     3,024,999,592.24
      2. Major investment and nancing activities irrelevant to cash income and
      expenses:
      Conversion of debts into capital                                                                 0.00                 0.00
      Convertible corporate bonds due within 1 year                                                    0.00                 0.00
      Fixed assets capitalised under nance leases                                                      0.00                 0.00
      3. Net change in cash and cash equivalents:
      Cash balance at the end of the period                                               11,697,518,141.18   12,122,781,311.49
      Less: Cash balance at the beginning of the period                                   12,122,781,311.49   10,940,305,225.81
      Add: Balance of cash equivalents at the end of the period                                        0.00                 0.00
      Less: Balance of cash equivalents at the beginning of the period                                 0.00                 0.00
      Net increase in cash and cash equivalents                                             -425,263,170.31     1,182,476,085.68


 (2) Net cash payment for acquisition of subsidiaries during the Period
     □ Applicable √ N/A




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(3). Net cash received from disposal of subsidiaries during the Period Item
     √ Applicable □ N/A
                                                                                                            Unit: Yuan Currency: RMB
     Item                                                                                                               For the Period
     Cash or cash equivalents received during the Period from disposal of subsidiaries during the Period                10,000,000.00
     Of which: Zhuhai Qiao Biotechnology Co., Ltd. ( 珠海启奥生物技术有限公司 )                                         10,000,000.00
     Less: Cash and cash equivalents held by subsidiaries on the date when the Company loses control                     6,688,779.47
     Of which:Zhuhai Qiao Biotechnology Co., Ltd. ( 珠海启奥生物技术有限公司 )                                           6,688,779.47
     Add: Cash or cash equivalents received during the Period from disposal of subsidiaries during previous
                                                                                                                                 0.00
     periods
     Net cash received from disposal of subsidiaries                                                                     3,311,220.53


(4). Composition of cash and cash equivalents
     √ Applicable □ N/A
                                                                                                            Unit: Yuan Currency: RMB
                                                                                Balance at the End         Balance at the Beginning
     Item
                                                                                     of the Period                     of the Period
     Ⅰ Cash                                                                     11,697,518,141.18                 12,122,781,311.49
     Of which: Cash on hand                                                             225,179.98                        197,923.25
         Bank deposits that are readily available for payment                    11,554,754,721.43                 12,031,569,238.87
        Other monetary funds that are readily available for payment                 142,538,239.77                      91,014,149.37
     Ⅱ Cash equivalents                                                                       0.00                              0.00
     Of which: Bond investments due within three months                                        0.00                              0.00
     III. Balance of cash and cash equivalents at the end of the period          11,697,518,141.18                 12,122,781,311.49


    Other descriptions:
    √ Applicable □ N/A
    Cash and cash equivalents excluded restricted cash and cash equivalents used by the Company.


60. Assets with restricted ownership or right of use
    √ Applicable □ N/A
                                                                                                            Unit: Yuan Currency: RMB
                                    Carrying amount at the
     Item                                                                                Reasons for restriction
                                         End of the Period
     Other monetary funds                    11,742,597.03          Deposits for L/C, bank acceptance draft and forward settlement
     Bills receivables                      870,153,979.75          Bills pooling business, pledged bills receivables
     Total                                  881,896,576.78          /




                                                                                                                                  235
61. Monetary items denominated in foreign currencies
(1). Monetary items denominated in foreign currencies
     √ Applicable □ N/A
                                                                                                            Unit: Yuan Currency: RMB
                                        Balance in foreign currency                                        Equivalent RMB balance
      Item                                                                       Exchange rate
                                            at the End of the Period                                        at the End of the Period
      Monetary funds                                               -                          -
      Of which: USD                                 203,360,894.88                      6.3757                     1,296,568,057.51
              Euro                                     77,484.76                     7.2197                           559,416.72
              HKD                                631,158,004.71                      0.8176                       516,034,784.66
              MOP                                   1,412,971.92                     0.7936                          1,121,334.52
                 JPY                                 43,429,022.00                    0.055415                          2,406,619.25
              GBP                                       1,940.10                     8.6064                             16,697.28
      Accounts receivables                                        -                          -
      Of which: USD                                  90,823,295.30                      6.3757                       579,062,083.84
                 Euro                                   622,350.00                      7.2197                         4,493,180.30
              MOP                                   3,559,534.45                     0.7936                         2,824,846.54
      Other receivables                                           -                          -
      Of which: HKD                                    3,317,918.13                     0.8176                         2,712,729.86
              MOP                                    581,188.00                      0.7936                           461,230.80
      Accounts payables                                          -                           -
      Of which: USD                                       33,452.83                     6.3757                           213,285.21
                 Euro                                      5,665.41                     7.2197                             40,902.56
              MOP                                      13,870.44                     0.7936                             11,007.58
      Other payables                                              -                          -
      Of which: HKD                                    3,061,615.96                     0.8176                         2,503,177.21
              USD                                   2,514,960.49                     6.3757                        16,034,633.60


(2). Descriptions of overseas operating entities, including disclosure of the main overseas
     business locations, functional currency and the basis for selection of important overseas operating entities, and the reasons for
     changes in functional currency (if any)
     □ Applicable √ N/A


62. Government grants
 1. Basic information of government grants
    √ Applicable □ N/A
                                                                                                            Unit: Yuan Currency: RMB
                                                                                                        Amount included in prot or
      Category                                              Amount       Line item
                                                                                                          loss for the current period
      Related to assets                              53,611,700.00       Deferred income
      Related to income                                 324,673.61       Deferred income
      Related to assets                              59,110,913.13       Other income                                 59,110,913.13
      Related to income                             186,224,227.56       Other income                                186,224,227.56




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2. Return of government grants
   √ Applicable □ N/A
                                                                                                                                                                          Unit: Yuan Currency: RMB
     Items                                                                                                                                             Amount                           Reasons
     Respiratory system inhalation preparation engineering laboratory project                                                                  151,700.00                       Balance returned
     Research and development and industrialization of non-steroidal
                                                                                                                                            5,000,000.00                        Project withdrawal
     anti-inammatory drug Celecoxib capsules
     Meropenem special fund subsidy                                                                                                       10,000,000.00                         Project withdrawal
     Meropenem Internationalization Project Subsidy                                                                                         3,300,000.00                        Project withdrawal
     Zhuhai innovation and enterprising team and high-level talent
                                                                                                                                            9,000,000.00                        Project withdrawal
     enterprising project (paclitaxel micellar for injection)
     China Postdoctoral Science Foundation subsidy funds                                                                                         80,000.00                      Re-appropriation
     Export credit insurance subsidies                                                                                                         407,687.30                       Re-appropriation
     Total                                                                                                                                27,939,387.30


     Other descriptions
(1). Government grants included in deferred income will be measured by gross amount method

                                                                                                                          Amount            Amount                                     Amount
                                                                                                   Balance at the                                                             Balance                 Related to
                                                                                                                     of additional        charged to           Other                   charged to
     Items of grants                                                               Type               Beginning                                                             at the End                assets/
                                                                                                                          grant for   prot and loss          changes                   prot and loss
                                                                                                      of the Year                                                        of the Period                income
                                                                                                                        the Period    for the Period                                   for the Period
     Study on the technology of antifungal drug caspofungin                        Fiscal                                                                                                             Related to
                                                                                                    1,500,000.00                 0     1,500,000.00                0               0 other income
     (抗真菌药卡泊芬净工艺研究)                                                    appropriation                                                                                                      assets
     Laboratory project of respiratory system inhalation preparation engineering Fiscal                                                                                                               Related to
                                                                                                    5,000,000.00                 0    1,346,750.00        151,700.00     3,501,550.00 other income
     laboratory project (呼吸系统吸入制剂工程实验室项目)                         appropriation                                                                                                        assets
     Construction of a recycling production base for carbapenem products(         Fiscal                                                                                                              Related to
                                                                                                    3,625,000.00                 0                0                0     3,625,000.00 other income
     碳青霉烯类系列产品循环化生产基地建设)                                        appropriation                                                                                                       assets
    Research and development and industrialization of non-steroidal anti-
                                                                          Fiscal                                                                                                                      Related to
      inammatory drug Celecoxib capsules                                                            5,000,000.00                 0                0      5,000,000.00              0 other income
                                                                          appropriation                                                                                                               assets
    (非甾体抗炎药物塞来昔布胶囊研发及产业化)
    Construction of an integrated production line for fully automatic blister-type
                                                                                   Fiscal                                                                                                             Related to
      dry powder inhalant micro-lling and winding                                                   2,420,000.00                 0     1,492,333.34                0      927,666.66 other income
                                                                                   appropriation                                                                                                      assets
    (全自动泡罩型干粉吸入剂微量灌封与卷绕一体化生产线建设)
      Change in National Science and Technology Major Project* Research funding
                                                                                Fiscal                                                                                                                Related to
      for lipid injection * Baiyunshan Hanfang transfer                                              150,000.00                  0                0                0      150,000.00 other income
                                                                                appropriation                                                                                                         assets
    (国家重大专项项目变更*注射脂质研究经费*白云山汉方转入)
     Research on common key technologies for the large-scale development of Fiscal                                                                                                                    Related to
                                                                                                     365,700.00                  0                0                0      365,700.00 other income
     new inhalation preparations(新型吸入制剂规模化发展共性关键技术研究) appropriation                                                                                                              assets
      Large-scale development subsidy for new inhalation preparations              Fiscal                                                                                                             Related to
                                                                                                    2,262,600.00                 0                0                0     2,262,600.00 other income
    (新型吸入制剂规模化发展补助)                                                 appropriation                                                                                                      assets
                                                                                   Fiscal                                                                                                             Related to
     Meropenem special fund subsidy(美罗培南专项资金补助)                                        10,000,000.00                 0                0     10,000,000.00              0 other income
                                                                                   appropriation                                                                                                      assets
      Project Subsidy of meropenem internationalization                            Fiscal                                                                                                             Related to
                                                                                                    3,300,000.00                 0                0      3,300,000.00              0 other income
    (美罗培南国际化项目补助)                                                     appropriation                                                                                                      assets
      Project Subsidy of Marine mollusk kinetic protein                            Fiscal                                                                                                             Related to
                                                                                                   23,840,000.00                 0                0                0    23,840,000.00 other income
    (海洋软体动物动能蛋白项目补助)                                               appropriation                                                                                                      assets
      New inhalation drug formulation creation project                             Fiscal                                                                                                             Related to
                                                                                                   54,154,400.00    13,094,000.00                 0                0    67,248,400.00 other income
    (新型吸入给药制剂创制项目)                                                   appropriation                                                                                                      assets
                                                                                   Fiscal                                                                                                             Related to
     Zhimu total sapogenin project(知母总皂甙元项目)                                              8,900,000.00                 0                0                0     8,900,000.00 other income
                                                                                   appropriation                                                                                                      assets
                                                                                   Fiscal                                                                                                             Related to
     Glucocorticoid inhalation suspension project(糖皮质混悬液项目)                                          0     3,600,000.00                 0                0     3,600,000.00 other income
                                                                                   appropriation                                                                                                      assets




                                                                                                                                                                                                           237
                                                                                                                           Amount            Amount                              Amount
                                                                                                    Balance at the                                                      Balance                 Related to
                                                                                                                      of additional        charged to     Other                  charged to
       Items of grants                                                              Type               Beginning                                                      at the End                assets/
                                                                                                                           grant for   prot and loss    changes                  prot and loss
                                                                                                       of the Year                                                 of the Period                income
                                                                                                                         the Period    for the Period                            for the Period
        Receive nancial appropriations for small molecule peptide projects          Fiscal                                                                                                      Related to
                                                                                                      399,999.84                  0        80,000.04         0      319,999.80 other income
      (收财政拨款用于小分子肽项目)                                                appropriation                                                                                               assets
                                                                                    Fiscal                                                                                                      Related to
       Leulu total sterone project(漏芦总甾酮项目)                                                 2,500,000.00                 0                0         0     2,500,000.00 other income
                                                                                    appropriation                                                                                               assets
      R&D of active substances with bone and joint repair and health care functions Fiscal                                                                                                      Related to
                                                                                                     1,077,356.16                 0      119,706.24          0      957,649.92 other income
      (具有骨关节修复与保健功能的活性物质研发)                                    appropriation                                                                                               assets
       Key technology research and development of budesonide nebulized inhalation Fiscal                                                                                                        Related to
                                                                                                     4,500,000.00                 0     1,991,666.67         0     2,508,333.33 other income
       solution(布地奈德雾化吸入溶液关键技术研发)                               appropriation                                                                                                 assets
                                                                                    Fiscal                                                                                                      Related to
       Return of land holding tax(土地使用税返还)                                                  3,674,691.16                 0      107,029.74          0     3,567,661.42 other income
                                                                                    appropriation                                                                                               assets
       Special Fund for environmental protection of wastewater membrane Fiscal                                                                                                                  Related to
                                                                                                         9,708.66                 0         9,708.66         0               0 other income
       concentration system(废水膜浓缩系统环保专项资金)               appropriation                                                                                                           assets
        Subsidies for The development of pharmaceutical APIs industry               Fiscal                                                                                                      Related to
                                                                                                    41,960,547.60                 0     1,219,192.66         0    40,741,354.94 other income
      (医药原料药行业发展支持资金补助)                                            appropriation                                                                                               assets
        Receive innovation voucher(Jingjin Filter Press Equipment)                Fiscal                                                                                                      Related to
                                                                                                      313,332.99                  0        80,000.20         0      233,332.79 other income
      (收创新券(景津压滤设备))                                                  appropriation                                                                                               assets
                                                                                    Fiscal                                                                                                      Related to
       Xinxiang High-tech Project Fund Support(新乡高新技术项目资金扶持)                           1,917,508.44                 0        56,397.36         0     1,861,111.08 other income
                                                                                    appropriation                                                                                               assets
        Hepatitis B vaccine methanol yeast expression system                        Fiscal                                                                                                      Related to
                                                                                                      500,000.00                  0      500,000.00          0               0 other income
      (乙肝疫苗甲醇酵母表达系统)                                                  appropriation                                                                                               assets
        New recombinant protein vaccine technology platform and Industrialization
                                                                                  Fiscal                                                                                                        Related to
        of Cervical Cancer Vaccine                                                                   9,000,002.00                 0     9,000,002.00         0               0 other income
                                                                                  appropriation                                                                                                 assets
      (新型重组蛋白疫苗技术平台及宫颈癌疫苗产业化)
       Development Zone Finance Bureau funded Start-ups Pioneer Entrepreneurs
       Project:Research on Common Co-construction Technology of Pharmaceutical Fiscal                                                                                                           Related to
                                                                                                     1,900,000.00      900,000.00                  0          0    2,800,000.00 other income
       Inhalation Preparations(开发区财政局拔款创业领军人才项目:药品吸入 appropriation                                                                                                         assets
       制剂共性共建技术的研究)
        Research and development of respiratory system drug and clinical research
                                                                                  Fiscal                                                                                                        Related to
        technology service platform project talent funding                                           1,500,000.00                 0                0         0     1,500,000.00 other income
                                                                                  appropriation                                                                                                 assets
      (呼吸系统药物研发和临床研究技术服务平台项目人才经费)
        Science and technology help the economy key special projects                Fiscal                                                                                                      Related to
                                                                                                      500,000.00                  0                0         0      500,000.00 other income
      (科技助力经济重点专项)                                                      appropriation                                                                                               assets
                                                                                    Fiscal                                                                                                      Related to
       City Service Development Special(市服务发展专项)                                             800,000.00                  0                0         0      800,000.00 other income
                                                                                    appropriation                                                                                               assets
                                                                                    Fiscal                                                                                                      Related to
       Patent funding(专利资助)                                                                               0      200,000.00                  0         0      200,000.00 other income
                                                                                    appropriation                                                                                               assets
       2020 Shanghai Professional Technology Platform Capacity Enhancement Fiscal                                                                                                               Related to
                                                                                                                0     1,000,000.00                 0         0     1,000,000.00 other income
       Project (2020年度上海市专业技术平台能力提升项目立项)                appropriation                                                                                                        assets
                                                                                    Fiscal                                                                                                      Related to
       high-growth small and micro innovation enterprises(高成长小微科创企业)                                   0      400,000.00                  0         0      400,000.00 other income
                                                                                    appropriation                                                                                               assets
        Research and development subsidy for ω-3-Fish Oil Medium and Long
                                                                           Fiscal                                                                                                               Related to
        Chain Fat Emulsion Injection                                                                  350,000.00                  0                0         0      350,000.00 other income
                                                                           appropriation                                                                                                        assets
      (ω-3鱼油中/长链脂肪乳注射液研究开发补助)
        R&D and industrialization of innovative Ilaprazole Series                   Fiscal                                                                                                      Related to
                                                                                                    20,988,166.29                 0     4,910,000.04         0    16,078,166.25 other income
      (艾普拉唑系列创新药物研发及产业化)                                          appropriation                                                                                               assets
      Research and development funds for new drug for Class I Treatment of
                                                                           Fiscal                                                                                                               Related to
        Necrosis Factor in Human Tumour from Human Source                                            8,000,000.00                 0                0         0     8,000,000.00 other income
                                                                           appropriation                                                                                                        income
      (I类治疗用人源化抗人肿瘤坏死因子α单克隆抗体新药研制资金)
        Strategic emerging industries in 2014 (sustained release microspheres)      Fiscal                                                                                                      Related to
                                                                                                    16,700,000.00                 0                0         0    16,700,000.00 other income
      (2014年战略性新兴产业(缓释微球))                                          appropriation                                                                                               assets
        Fund for industrialization of prolonged-action microsphere preparation      Fiscal                                                                                                      Related to
                                                                                                    13,300,000.00                 0      750,000.00          0    12,550,000.00 other income
      (长效微球制剂的产业化款项)                                                  appropriation                                                                                               assets
       Construction project for industrialization of prolonged-action microsphere Fiscal                                                                                                        Related to
                                                                                                     7,024,025.85    15,329,800.00      1,634,320.37         0    20,719,505.48 other income
       preparation (phase I)(长效微球制剂产业化建设项目(一期工程))            appropriation                                                                                                 assets



238
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                                                                                                                                                                               2021


                                                                                                                    Amount            Amount                              Amount
                                                                                              Balance at the                                                     Balance                 Related to
                                                                                                               of additional        charged to     Other                  charged to
 Items of grants                                                              Type               Beginning                                                     at the End                assets/
                                                                                                                    grant for   prot and loss    changes                  prot and loss
                                                                                                 of the Year                                                of the Period                income
                                                                                                                  the Period    for the Period                            for the Period
 Pilot-scale enlargement and industrialization of prolonged-action injection Fiscal                                                                                                      Related to
                                                                                               2,400,000.00                0     2,400,000.00         0               0 other income
 microsphere products(长效注射微球产品的中试放大和产业化)                  appropriation                                                                                               assets
  Project subsidy from the Ministry of Industry and Information Technology    Fiscal                                                                                                     Related to
                                                                                               2,400,000.00                0                0         0     2,400,000.00 other income
(工业和信息化部项目补助款)                                                  appropriation                                                                                              assets
Project subsidy from the Ministry of Industry and Information Technology      Fiscal                                                                                                     Related to
                                                                                               1,597,750.00                0      231,000.00          0     1,366,750.00 other income
(工业和信息化部项目补助款)                                                  appropriation                                                                                              assets
Construction of Drug Conformity Evaluation Research Center Platform           Fiscal                                                                                                     Related to
                                                                                               1,200,000.10                0      159,999.96          0     1,040,000.14 other income
(药物一致性评价研究中心平台建设)                                            appropriation                                                                                              assets
  R&D and Commercialisation of Mouse Nerve Growth Factor for Injection        Fiscal                                                                                                     Related to
                                                                                              50,606,036.20                0    10,560,089.27         0    40,045,946.93 other income
(注射用鼠神经生长因子研发及产业化)                                          appropriation                                                                                              assets
  Demonstration project on the application of solar photovoltaic architecture Fiscal                                                                                                     Related to
                                                                                               3,557,499.51                0     1,102,000.08         0     2,455,499.43 other income
(太阳能光电建筑应用示范项目)                                                appropriation                                                                                              assets
Subsidy for the Tender of Technology Upgrade Project for PVC Soft Bag
                                                                      Fiscal                                                                                                             Related to
  Supported by Provincial Finance Departments                                                  3,111,850.32                0      408,365.76          0     2,703,484.56 other income
                                                                      appropriation                                                                                                      assets
(省财政支持技改招标项目补助金PVC软袋)
 Technical transformation project of Shenqi Fuzheng Injection with flexible Fiscal                                                                                                       Related to
                                                                                              19,500,000.02                0     3,823,529.40         0    15,676,470.62 other income
 bag(软袋参芪扶正注射液技改项目)                                          appropriation                                                                                                assets
  Provision for technology transformation funds and subsequent grants         Fiscal                                                                                                     Related to
                                                                                               6,589,119.08                0     1,129,563.36         0     5,459,555.72 other income
(技术改造资金拨款及事后补奖)                                                appropriation                                                                                              assets
  Provision for technology transformation funds and subsequent grants         Fiscal                                                                                                     Related to
                                                                                              10,648,600.33                0     3,288,929.52         0     7,359,670.81 other income
(技术改造资金拨款及事后补奖)                                                appropriation                                                                                              assets
Electricity distribution transformer performance enhancement for energy-
                                                                         Fiscal                                                                                                          Related to
  saving and emission reduction projects                                                        428,000.00                 0        48,000.00         0      380,000.00 other income
                                                                         appropriation                                                                                                   assets
(节能减排项目配电变压器能效提升)
  R&D and industrialization team of chemical drug liquid preparation          Fiscal                                                                                                     Related to
                                                                                               1,000,000.00    1,008,000.00       473,166.56          0     1,534,833.44 other income
(化药液体制剂研发与产业化团队)                                              appropriation                                                                                              assets
  Innovation capacity building of technology center (antibody laboratory)     Fiscal                                                                                                     Related to
                                                                                               5,248,234.16                0      445,755.36          0     4,802,478.80 other income
(技术中心创新能力建设(抗体药物实验室))                                    appropriation                                                                                              assets
  Innovation capacity building of technology center (antibody laboratory)     Fiscal                                                                                                     Related to
                                                                                                241,769.82                 0        75,330.36         0      166,439.46 other income
(技术中心创新能力建设(抗体药物实验室))                                    appropriation                                                                                              income
Achievement transfer of blood screening (BCI) nucleic acid detection testing Fiscal                                                                                                      Related to
                                                                                               6,000,000.00                0     2,038,717.56         0     3,961,282.44 other income
(血液筛查(BCI)核酸检测试剂成果转化)                                      appropriation                                                                                               assets
 Technological upgrading and transformation projects of workshop for
                                                                         Fiscal                                                                                                          Related to
 acarbose (APIs for α-glucosidase inhibitor)(α-葡萄糖苷酶抑制剂类原料                        571,428.64                 0      107,142.84          0      464,285.80 other income
                                                                         appropriation                                                                                                   assets
 药阿卡波糖生产车间工艺升级技术改造项目)
                                                                              Fiscal                                                                                                     Related to
 R&D and industrialization of Statins(降血脂他汀类药物的研发与产业化)                           60,000.36                0        29,999.88         0       30,000.48 other income
                                                                              appropriation                                                                                              assets
  Scientic technology award and subsidy for technological innovative project Fiscal                                                                                                      Related to
                                                                                                139,491.80                 0      110,925.60          0       28,566.20 other income
(科学技术奖及科技创新项目资助)                                             appropriation                                                                                               assets
  Scientic technology award and subsidy for technological innovative project Fiscal                                                                                                      Related to
                                                                                               3,400,000.00                0     1,200,000.00         0     2,200,000.00 other income
(科学技术奖及科技创新项目资助)                                             appropriation                                                                                               income
 Zhuhai industrial enterprise“cloud and platform”service coupons supporting Fiscal                                                                                                     Related to
                                                                                                 114,972.73                0        25,540.87         0       89,431.86 other income
 funds(珠海市工业企业“云上平台”服务券支持资金)                            appropriation                                                                                              income
                                                                              Fiscal                                                                                                     Related to
 Commissioner workstation(特派员工作站)                                                       145,000.00                 0        60,000.00         0       85,000.00 other income
                                                                              appropriation                                                                                              assets
                                                                              Fiscal                                                                                                     Related to
 Industrial revitalisation supporting funds(产业振兴扶持资金)                                3,603,500.01                0     1,158,000.00         0     2,445,500.01 other income
                                                                              appropriation                                                                                              assets
  Phase IV clinical study of innovative drug Ilaprazole                       Fiscal                                                                                                     Related to
                                                                                               8,210,800.00                0                0         0     8,210,800.00 other income
(创新药物艾普拉唑IV期临床研究)                                              appropriation                                                                                              assets
                                                                              Fiscal                                                                                                     Related to
 Government grant for industrial transformation(工业转型政府扶持资金)                         508,333.67                 0      199,999.92          0      308,333.75 other income
                                                                              appropriation                                                                                              assets
                                                                              Fiscal                                                                                                     Related to
 New industrialization development grant(新型工业化发展奖金)                                 1,304,166.42    2,629,900.00       350,000.04          0     3,584,066.38 other income
                                                                              appropriation                                                                                              assets




                                                                                                                                                                                              239
                                                                                                                            Amount            Amount                                   Amount
                                                                                                      Balance at the                                                          Balance                 Related to
                                                                                                                       of additional        charged to         Other                   charged to
       Items of grants                                                               Type                Beginning                                                          at the End                assets/
                                                                                                                            grant for   prot and loss        changes                   prot and loss
                                                                                                         of the Year                                                     of the Period                income
                                                                                                                          the Period    for the Period                                 for the Period
        Policy fund for leading industrial enterprises loan Interests                Fiscal                                                                                                           Related to
                                                                                                        566,666.61                 0      200,000.04               0      366,666.57 other income
      (工业龙头企业贷款贴息政策资金)                                               appropriation                                                                                                    assets
       Supporting funds for ve advantageous industrial clusters and one high-tech Fiscal                                                                                                              Related to
                                                                                                        400,000.16                 0        99,999.96              0      300,000.20 other income
       industry(五优一新扶持资金)                                               appropriation                                                                                                       assets
                                                                                     Fiscal                                                                                                           Related to
       Subsidy for new R&D institution(新型研发机构补助)                                             2,000,000.00                0     2,000,000.00              0               0 other income
                                                                                     appropriation                                                                                                    assets
        Zhuhai innovation and enterprising team and high-level talent enterprising
                                                                                   Fiscal                                                                                                             Related to
        project (paclitaxel micellar for injection)                                                    2,700,000.00    6,300,000.00                 0    9,000,000.00              0 other income
                                                                                   appropriation                                                                                                      assets
      (珠海市创新创业团队和高层次人才创业项目(注射液紫杉醇胶束))
        Capital project for innovation and entrepreneurship team funding program     Fiscal                                                                                                           Related to
                                                                                                       8,500,000.00    4,000,000.00                 0              0    12,500,000.00 other income
      (创新创业团队资助计划资金项目)                                               appropriation                                                                                                    assets
       2020 Zhuhai City Innovation and Entrepreneurship Team (Nanocrystalline) Fiscal                                                                                                                 Related to
                                                                                                                  0    1,500,000.00                 0              0     1,500,000.00 other income
       (2020年度珠海市创新创业团队(纳米晶))                                  appropriation                                                                                                          assets
        Fund for R&D and industrialization of innovative Ilaprazole series           Fiscal                                                                                                           Related to
                                                                                                       5,600,000.00                0                0              0                other income
      (艾普拉唑系列创新药物研发及产业化项目资金)                                   appropriation                                                                                                    assets
      Key projects of industrial core and key technologies of Zhuhai (Ryanodex) Fiscal                                                                                                                Related to
                                                                                                       3,000,000.00                0                0              0                other income
      (珠海市产业核心和关键技术攻关方向项目(丹曲林钠))                      appropriation                                                                                                         assets
        Data-driven industrial chain collaboration platform demonstration project    Fiscal                                                                                                           Related to
                                                                                                                  0    3,650,000.00                 0              0     3,650,000.00 other income
      (数据驱动的产业链协同平台示范项目)                                           appropriation                                                                                                    assets
       Fund for key projects of industrial core and key technologies of Zhuhai (2nd Fiscal                                                                                                            Related to
                                                                                                       2,000,000.00                0                0              0     2,000,000.00 other income
       batch)(珠海市产业核心和关键技术攻关方向项目资金(第二批))                 appropriation                                                                                                     assets
        Innovative drug of Ilaprazole sodium for injection                           Fiscal                                                                                                           Related to
                                                                                                       2,400,000.00                0                0              0     2,400,000.00 other income
      (创新药注射用艾普拉唑钠针剂)                                                 appropriation                                                                                                    assets
        Technological transformation projects of new Cefuroxime                      Fiscal                                                                                                           Related to
                                                                                                       1,533,100.00                0                0              0     1,533,100.00 other income
      (新型头孢粉针剂技术改造项目)                                                 appropriation                                                                                                    assets
        Internet benchmarking project for advanced drug Manufacturing                Fiscal                                                                                                           Related to
                                                                                                        765,000.00                 0        90,000.00              0      675,000.00 other income
      (先进药品制造互联网标杆项目)                                                 appropriation                                                                                                    assets
                                                                                     Fiscal                                                                                                           Related to
       Cleaner Production Audit Project(清洁生产审核项目)                                             190,000.04                 0         9,999.96              0      180,000.08 other income
                                                                                     appropriation                                                                                                    assets
                                                                                     Fiscal                                                                                                           Related to
       Green factory(绿色工厂)                                                                       1,261,666.67                0      129,999.96               0     1,131,666.71 other income
                                                                                     appropriation                                                                                                    assets
                                                                                     Fiscal                                                                                                           Related to
       HCG project construction(HCG项目建设)                                                         3,783,485.81                0      395,649.97               0     3,387,835.84 other income
                                                                                     appropriation                                                                                                    assets
                                                                                     Fiscal                                                                                                           Related to
       Sewage treatment system upgrade project(污水处理系统升级改造项目)                                72,269.96                0         8,030.04              0       64,239.92 other income
                                                                                     appropriation                                                                                                    assets
       R&D and industrialization of Recombinant Human Chorionic Gonadotropin Fiscal                                                                                                                   Related to
                                                                                                       1,287,500.00                0      150,000.00               0     1,137,500.00 other income
       for Injection(注射用重组人绒促性素研发及产业化)                     appropriation                                                                                                            assets
       Subsidies for online monitoring equipment and installations of coalfired Fiscal                                                                                                                Related to
                                                                                                        105,000.00                 0        22,500.00              0       82,500.00 other income
       boilers(燃煤锅炉在线监控设备装置补助资金)                              appropriation                                                                                                         assets
      Funds for joint R&D and industrialization of integrated platform for
                                                                           Fiscal                                                                                                                     Related to
        molecular diagnostics                                                                          1,550,000.00                0     1,368,367.88              0      181,632.12 other income
                                                                           appropriation                                                                                                              assets
      (集成一体化分子诊断平台的合作研发及产业化资金)
      Project supporting fund for the first batch of special funds for scientific and
                                                                                      Fiscal                                                                                                          Related to
      technological innovation in 2019                                                                  850,000.00                 0      250,000.00               0      600,000.00 other income
                                                                                      appropriation                                                                                                   assets
      (2019年度第一批科技创新专项资金立项配套资助)
       Provincial industrial innovation (provincial enterprise technology center) Fiscal                                                                                                              Related to
                                                                                                       1,403,733.33                0      357,200.00               0     1,046,533.33 other income
       project in 2019(2019年省产业创新(省级企业技术中心)项目)                appropriation                                                                                                       assets
        Guangdong Province Science and Technology Department special emergency
      fund for scientific and technological research on prevention and control of Fiscal                                                                                                              Related to
                                                                                                        350,000.00                 0      350,000.00               0               0 other income
        COVID-19                                                                  appropriation                                                                                                       assets
      (广东省科学技术厅汇防控新型冠状病毒感染科技攻关应急专项款)
       Zhuhai Financial Bureau cum COVID-19 emergency technology special Fiscal                                                                                                                       Related to
                                                                                                        250,000.00                 0      250,000.00               0               0 other income
       emergency fund(珠海市财政局汇新冠应急科技攻关专项款)            appropriation                                                                                                                assets




240
                                                                                                                                                                                        Annual Report
                                                                                                                                                                                                2021


                                                                                                                              Amount             Amount                                    Amount
                                                                                                       Balance at the                                                             Balance                 Related to
                                                                                                                         of additional         charged to          Other                   charged to
     Items of grants                                                                 Type                 Beginning                                                             at the End                assets/
                                                                                                                              grant for    prot and loss         changes                   prot and loss
                                                                                                          of the Year                                                        of the Period                income
                                                                                                                            the Period     for the Period                                  for the Period
      China Postdoctoral Science Foundation subsidy funds                            Fiscal                                                                                                               Related to
                                                                                                         160,000.00                  0                 0        80,000.00      80,000.00 other income
    (中国博士后科学基金会资助经费)                                                 appropriation                                                                                                        income
     Pre-appropriation of special grants for industrialization of diagnostic reagents Fiscal                                                                                                              Related to
                                                                                                        4,601,200.00                 0       484,784.35                0     4,116,415.65 other income
     for COVID-19(新型冠状病毒检测试剂产业化项目补助金预拨)                         appropriation                                                                                                       assets
    Xiangzhou District equipment purchase subsidy supporting funds (special
                                                                            Fiscal                                                                                                                        Related to
      funds for prevention and control of pandemic)                                                        13,555.75                 0          2,088.50               0       11,467.25 other income
                                                                            appropriation                                                                                                                 assets
    (香洲区购置设备补贴扶持资金(疫情防控专项资金))
      Zhuhai innovation and enterprising team and high-level talent enterprising
                                                                                 Fiscal                                                                                                                   Related to
      project Phase I funds                                                                            12,000,000.00                 0                 0               0    12,000,000.00 other income
                                                                                 appropriation                                                                                                            assets
    (珠海市创新创业团队和高层次人才创业项目首期资金)
      Overall relocation and deployment expansion project                            Fiscal                                                                                                               Related to
                                                                                                       20,000,000.00                 0                 0               0    20,000,000.00 other income
    (整体搬迁调迁扩建项目)                                                         appropriation                                                                                                        assets
    Environmental protection bureau RTO project special funds                        Fiscal                                                                                                               Related to
                                                                                                         200,000.00                  0         20,000.04               0      179,999.96 other income
    (环保局RTO项目资金)                                                            appropriation                                                                                                        assets
     Structure-eciency optimization of marine microorganisms and evaluation of Fiscal                                                                                                                     Related to
                                                                                                                   0       324,673.61          12,307.34               0      312,366.27 other income
     antitumor activity (海洋微生物构效优化与抗肿瘤活性评价)                   appropriation                                                                                                              income
     Total                                                                                           467,562,770.49    53,936,373.61      60,424,091.70    27,531,700.00 433,543,352.40                  


(2) Government grants charged to prot and loss for the Period by adopting gross amount method

                                                                                                                                                     Amount            Amount
                                                                                                                                                                                Presentation
                                                                                                                                                   charged to       charged to                   Related to assets/
     Projects with grants                                                                                                  Type                                                 item in prot
                                                                                                                                               prot and loss     prot and loss                   income
                                                                                                                                                                                and loss
                                                                                                                                                for Last Year      for the Year
     Social security subsidy(社保补助)                                                                            Fiscal appropriation          417,699.36         72,684.89 Other income Related to income
     Patent grant(专利补助)                                                                                       Fiscal appropriation          300,000.00        300,000.00 Other income Related to income
     Job stabilization subsidy(稳岗补贴)                                                                          Fiscal appropriation          802,889.91        122,853.35 Other income Related to income
     Electricity subsidy(用电补助)                                                                                Fiscal appropriation        1,293,613.03      1,245,193.22 Other income Related to income
     Maternity benets(生育津贴)                                                                                   Fiscal appropriation           56,229.56        298,510.00 Other income Related to income
      Marine small molecule peptide beauty moisturizing health drink project
                                                                                                                    Fiscal appropriation           80,000.04         80,000.04 Other income Related to assets
    (海洋小分子肽美容补水保健饮料项目)
      The acceptance of the budesonide project is transferred to other income
                                                                                                                    Fiscal appropriation                    0     1,991,666.67 Other income Related to assets
    (布地奈德项目验收转其他收益)
     Recruitment subsidy for college graduates (高校毕业生招用补贴)                                                 Fiscal appropriation                    0        59,000.00 Other income Related to income
     Enterprise pre job training subsidy in 2020 (20年企业岗前培训补贴)                                             Fiscal appropriation                    0          7,400.00 Other income Related to income
     Enterprise R&D investment plan (企业研发投入计划)                                                              Fiscal appropriation                    0     2,000,000.00 Other income Related to income
     Domestic and foreign invention patent funding in 2020 (20年国内外发明专利资助款)                               Fiscal appropriation                    0          2,500.00 Other income Related to income
     Job training subsidy (适岗培训补贴)                                                                            Fiscal appropriation                    0       236,835.00 Other income Related to income
     2020 National High-tech Enterprise Recognition Award Subsidy Fund
                                                                                                                    Fiscal appropriation                    0        50,000.00 Other income Related to income
     (2020年国家高新技术企业认定奖补助资金)
     Subsidy for waste treatment costs in 2020 (20年污废处理费用补助)                                               Fiscal appropriation                    0        63,500.00 Other income Related to income
     National High-tech Enterprise Cultivation Support Program (国家高新技术企业培增支持计划)                      Fiscal appropriation                    0       100,000.00 Other income Related to income
     Construction of an integrated production line for fully automatic blister-type dry powder inhalant
                                                                                                                    Fiscal appropriation                    0     1,492,333.34 Other income Related to assets
     micro-lling and winding (全自动泡罩型干粉吸入剂微量灌封与卷绕一体化生产线建设)
     Study on the technology of antifungal drug caspofungin (抗真菌药卡泊芬净工艺研究)                              Fiscal appropriation                    0     1,500,000.00 Other income Related to assets
     Laboratory project of respiratory system inhalation preparation engineering laboratory project
                                                                                                                    Fiscal appropriation                    0     1,346,750.00 Other income Related to assets
     (呼吸系统吸入制剂工程实验室项目)
     Zhang Bin Industry and Information Development Special Fund * 2018 Technology Center
                                                                                                                    Fiscal appropriation                    0       260,527.00 Other income Related to income
     Improvement (张斌工信发展专项经费*2018技术中心提升)



                                                                                                                                                                                                               241
                                                                                                                                         Amount           Amount
                                                                                                                                                                   Presentation
                                                                                                                                       charged to      charged to                 Related to assets/
       Projects with grants                                                                                        Type                                            item in prot
                                                                                                                                   prot and loss    prot and loss                 income
                                                                                                                                                                   and loss
                                                                                                                                    for Last Year     for the Year
       Subsidy funds for the improvement of atmospheric environment quality *Shenzhen Ecological
                                                                                                            Fiscal appropriation               0      153,240.00 Other income Related to income
       Environment Bureau (大气环境质量提升补贴资金*深圳生态环境局)
       Amortization of special funds for powder spray production line (粉雾生产线专项资金项目摊销)          Fiscal appropriation               0      200,000.00 Other income Related to income
       Grant on the technology of antifungal drug caspofungin (抗真菌药卡泊芬净工艺补助)                    Fiscal appropriation               0       87,438.00 Other income Related to income
       Amortization of special funds for engineering laboratories (工程实验室专项资金项目摊销)              Fiscal appropriation               0       72,400.00 Other income Related to income
       Export insurance premium subsidy(June-December, 2019)
                                                                                                            Fiscal appropriation               0       10,000.00 Other income Related to income
       (2019年06-12月出口用保险保费补助款)
       The 9th batch of job training subsidies for enterprises in Yantian District in 2020
                                                                                                            Fiscal appropriation               0    2,880,000.00 Other income Related to income
       (2020年盐田区企业适岗培训补贴第9批次)
        The rst batch of funding support for the development of science and technology industries in 2021
                                                                                                            Fiscal appropriation               0    3,000,000.00 Other income Related to income
      (2021年第一批科技类产业发展资金扶持资助)
       Export insurance premium subsidy(January-June, (2020年01-06月出口用保险保费资助款) Fiscal appropriation                              0       50,000.00 Other income Related to income
       2015 Pilot Project of United Development of Emerging Strategic Industrial Regions in Guangdong
                                                                                                            Fiscal appropriation               0    9,500,002.00 Other income Related to assets
       Province (2015年广东省战略性新兴产业区域集聚发展试点项目)
       Return of land holding tax(土地使用税返还)                                                         Fiscal appropriation     107,029.74       107,029.74 Other income Related to assets
        Construction of 500 cubic meters/day wastewater membrane concentration system
                                                                                                            Fiscal appropriation       58,252.42        9,708.66 Other income Related to assets
      (建设500立方米/日废水膜浓缩系统)
       Subsidy funds allocated by the Bureau of Finance(财政局拨付补助资金)                               Fiscal appropriation    1,219,192.66    1,219,192.66 Other income Related to assets
       Innovation voucher- buy Jingjin Filter Press Equipment (创新券-购买景津压滤设备)                     Fiscal appropriation       80,000.14       80,000.20 Other income Related to assets
        Export insurance premium subsidy(January-June, 2019)
                                                                                                            Fiscal appropriation     403,700.00                0 Other income Related to income
      (2019年上半年出口信保补贴资金)
       2020 Special Fund for Foreign Economic and Trade Development (2020年度外经贸发展专项资金)            Fiscal appropriation     365,000.00                0 Other income Related to income
      Special funds for the development of advanced manufacturing industry in Henan Province
                                                                                                            Fiscal appropriation    2,000,000.00               0 Other income Related to income
      (河南省先进制造业发展专项资金)
       Subsidies for Credit insurance and SME in second half of 2018 (2018年下半年信报和中小开补贴)         Fiscal appropriation     714,100.00                0 Other income Related to income
       Subsidies for SME in the second half of 2016 (2016年下半年中小开补贴)                                Fiscal appropriation       90,700.00               0 Other income Related to income
       Export insurance premium subsidy(January-June, 2017) (2017年上半年出口信保项目补贴)                 Fiscal appropriation     333,200.00                0 Other income Related to income
       Export insurance premium subsidy in 2016 (2016年出口信保项目补贴)                                    Fiscal appropriation     522,000.00                0 Other income Related to income
       Government grants special funds for the development of small and medium-sized enterprises
                                                                                                            Fiscal appropriation    1,412,200.00               0 Other income Related to income
       (政府补助中小企业发展专项资金)
       Subsidies for work-based training(以工代训补贴)                                                    Fiscal appropriation     387,358.50        77,547.17 Other income Related to income
       Advanced Group and Advanced Individual Subsidy in 2020(2020年度先进集团和先进个人补助) Fiscal appropriation                           0       20,000.00 Other income Related to income
       Special funds for corporate R&D nancial subsidies in 2020(2020年企业研发财政补助专项资金) Fiscal appropriation                        0      720,000.00 Other income Related to income
       Government subsidies for ood (政府洪涝补助)                                                          Fiscal appropriation               0      200,000.00 Other income Related to income
       Special funds for foreign trade and economic development(外经贸发展专项资金)                         Fiscal appropriation               0      200,000.00 Other income Related to income
       Special funds for corporate R&D nancial subsidies in 2021(2021年企业研发财政补助专项资金) Fiscal appropriation                        0      270,000.00 Other income Related to income
       Provincial special funds for basic conditions of science and technology (省科技基础条件专项经费)     Fiscal appropriation       10,000.00               0 Other income Related to income
       Government subsidy - support the elimination of national Ⅲ-car incentives
                                                                                                            Fiscal appropriation       18,000.00               0 Other income Related to income
       (政府补助-支持淘汰国三车奖励)
       The second batch of patent funding in 2018 (2018年第二批专利资助)                                    Fiscal appropriation       10,000.00               0 Other income Related to income
       National Quality Enterprise Supporting Award (国家级优势企业配套奖)                                  Fiscal appropriation     200,000.00                0 Other income Related to income
       Overseas trademark subsidies (境外商标补贴)                                                          Fiscal appropriation       10,000.00               0 Other income Related to income
       Corporate Income Tax Return (企业所得税返还)                                                         Fiscal appropriation          419.73               0 Other income Related to income
       Amortized Study of Donipenem Government Subsidies (摊销研究多尼培南政府补贴)                         Fiscal appropriation     300,000.00                0 Other income Related to assets
       Subsidies for work-based training(以工代训)                                                        Fiscal appropriation     541,500.00                0 Other income Related to income
       Pandemic Donation (疫情捐赠)                                                                         Fiscal appropriation       78,230.09               0 Other income Related to income



242
                                                                                                                                                              Annual Report
                                                                                                                                                                      2021


                                                                                                                              Amount           Amount
                                                                                                                                                        Presentation
                                                                                                                            charged to      charged to                 Related to assets/
 Projects with grants                                                                                   Type                                            item in prot
                                                                                                                        prot and loss    prot and loss                 income
                                                                                                                                                        and loss
                                                                                                                         for Last Year     for the Year
 Intellectual Property Rights Protection Funding (知识产权维权资助)                              Fiscal appropriation     131,740.03                0 Other income Related to income
 Government Patent Grants in 2020 (2020年政府专利资助)                                           Fiscal appropriation               0        9,000.00 Other income Related to income
 The third batch of biopharmaceutical industry leader (第三批次生物医药产业领航)                 Fiscal appropriation               0      500,000.00 Other income Related to income
 Quality brand double promotion support plan (质量品牌双提升扶持计划)                            Fiscal appropriation               0      400,000.00 Other income Related to income
 The rst batch of funding for the 2019 Enterprise Research and Development Funding Program
                                                                                                 Fiscal appropriation    1,018,000.00               0 Other income Related to income
 (2019年企业研究开发资助计划第一批资助)
 The rst batch of funding for the 2020 Enterprise Research and Development Funding Program
                                                                                                 Fiscal appropriation               0      871,000.00 Other income Related to income
 (2020年企业研究开发资助计划第一批资助)
 The Shenzhen Industrial Stable Growth Fund 100 million key enterprise funding in 2019
                                                                                                 Fiscal appropriation     300,000.00                0 Other income Related to income
 (2019年深圳市工业稳定增长资金1亿级重点企业资助经费)
 The second and third batches of atmospheric environment quality improvement subsidies in 2020
                                                                                                 Fiscal appropriation     200,000.00                0 Other income Related to income
 *Shenzhen Finance Bureau (2020年第二、三批大气环境质量提升补贴*深圳市财政局)
 2020 Shenzhen Intellectual Property Operation Service System Construction Special Fund-funded
                                                                                                 Fiscal appropriation     226,000.00                0 Other income Related to income
 Project (2020年度深圳市知识产权运营服务体系建设专项资金资助项目)
 Support Program Grants in 2020 (2020年扶持计划资助款)                                           Fiscal appropriation     953,000.00                0 Other income Related to income
 Subsidy for sewage charges (排污费补贴)                                                        Fiscal appropriation       72,785.25               0 Other income Related to income
 Enterprise les and cards for poor labor subsidies(企业建档立卡贫困劳动力补贴)                 Fiscal appropriation       15,000.00               0 Other income Related to income
  Enterprises absorb one-time subsidy for poor labor and employment
                                                                                                 Fiscal appropriation       10,000.00               0 Other income Related to income
(企业吸纳建档立卡贫困劳动就业一次性补贴)
 Export credit insurance funding in 2018(2018年出口信用保险资助经费)                           Fiscal appropriation     184,732.00                0 Other income Related to income
 Donation of COVID-19 (新冠疫情捐赠)                                                             Fiscal appropriation     312,920.35                0 Other income Related to income
 Industrial Development Fund in Yantian Distict (盐田区产业发展资金)                             Fiscal appropriation     500,000.00                0 Other income Related to income
 Government funding* (technical transformation) (政府资助*(技术改造))                          Fiscal appropriation       70,000.00       60,000.00 Other income Related to income
 Government funding* (COVID-19) (政府资助*(新冠肺炎))                                          Fiscal appropriation     200,000.00                0 Other income Related to income
 Government subsidies for the Quality and Brand Double Improvement Funding Program
                                                                                                 Fiscal appropriation     800,000.00                0 Other income Related to income
 (质量品牌双提升资助计划政府补助)
 Enterprise support funds (企业扶持资金)                                                         Fiscal appropriation     350,000.00                0 Other income Related to income
 2019 fresh graduates apply for living allowance (2019应届毕业生申请生活补贴)                    Fiscal appropriation        7,333.00               0 Other income Related to income
 District Innovation Voucher Funding(区创新券资助)                                             Fiscal appropriation       17,600.00      150,000.00 Other income Related to income
 2019 fresh graduates apply for living allowance (2019应届毕业生社保补贴)                        Fiscal appropriation        1,338.30               0 Other income Related to income
 Recognition and reward of high-tech enterprises (高企认定奖励)                                  Fiscal appropriation     200,000.00       200,000.00 Other income Related to income
 R&D Innovation Award (研发创新奖励)                                                             Fiscal appropriation     779,900.00        19,764.00 Other income Related to income
 Resumption of work and production (复工复产)                                                    Fiscal appropriation        6,500.00        1,000.00 Other income Related to income
 Shanghai Pudong New District Intellectual Property Protection Center
                                                                                                 Fiscal appropriation        4,000.00               0 Other income Related to income
 (上海市浦东新区知识产权保护中心)
 Training allowance (培训补贴)                                                                   Fiscal appropriation        4,200.00        3,000.00 Other income Related to income
 Supporting the Industrialization of Innovative Achievements - Biomedicine
                                                                                                 Fiscal appropriation    2,000,000.00               0 Other income Related to income
 (支持创新成果产业—生物医药)
 Research and development of respiratory system drug and clinical research technology service
                                                                                                 Fiscal appropriation    1,500,000.00               0 Other income Related to income
 platform project talent funding (呼吸系统药物研发和临床研究技术服务平台项目人才经费)
 Special subsidy of Guangzhou technology-based small and medium-sized enterprises technology
                                                                                                 Fiscal appropriation    1,500,000.00               0 Other income Related to assets
 innovation in 2020 (2020年广州市科技型中小企业技术创新专题补助)
 Subsidies for leading talents in Guangzhou Development Zone Science and Technology Innovation
 Bureau (Huangpu Science and Technology Bureau)                                                  Fiscal appropriation     226,844.00       278,460.00 Other income Related to income
 (广州开发区科技创新局(黄埔区科技局)区领军人才场地补贴)
 Social insurance subsidies for recruiting non-employment diculties in 2020
                                                                                                 Fiscal appropriation       24,905.08       61,986.60 Other income Related to income
 (2020年招用非就业困难人员社会保险补贴)



                                                                                                                                                                                     243
                                                                                                                                    Amount           Amount
                                                                                                                                                              Presentation
                                                                                                                                  charged to      charged to                 Related to assets/
      Projects with grants                                                                                    Type                                            item in prot
                                                                                                                              prot and loss    prot and loss                 income
                                                                                                                                                              and loss
                                                                                                                               for Last Year     for the Year
      Value-added tax deduction (增值税加计抵减)                                                       Fiscal appropriation       65,792.65      114,614.53 Other income Related to income
      Supporting funds for science and technology awards in the rst half of 2020
                                                                                                       Fiscal appropriation     750,000.00                0 Other income Related to income
      (2020年上半年科技奖励配套资金)
      2020 provincial science and technology innovation strategy special fund
                                                                                                       Fiscal appropriation     100,000.00                0 Other income Related to income
      (2020年度省科技创新战略专项资金)
      Subsidies for work-based training in 2020(2020年以工代训补贴)                                  Fiscal appropriation       17,000.00               0 Other income Related to income
      Shanghai domestic invention patent (上海市国内发明专利)                                          Fiscal appropriation               0        5,500.00 Other income Related to income
      One-time employment (一次性吸纳就业)                                                             Fiscal appropriation               0       16,000.00 Other income Related to income
      Preclinical study of targeted anti-tumor innovative drug JK00265
                                                                                                       Fiscal appropriation               0      500,000.00 Other income Related to income
      (靶向抗肿瘤创新药物JK00265临床前研究)
      Innovative talent support during the“13th Five-Year Plan”period in Pudong New Distict
                                                                                                       Fiscal appropriation               0       28,800.00 Other income Related to income
      (浦东新区“十三五”期间创新型人才扶持)
      Shanghai Zhangjiang Special Fund (上海张江专项资金)                                              Fiscal appropriation               0      100,000.00 Other income Related to income
      Science and Technology Development Fund for Enterprise R&D Institutions in Pudong New District
                                                                                                       Fiscal appropriation               0      800,000.00 Other income Related to income
      浦东新区科技发展基金企业研发机构专项
      Gazelle Enterprise Direct Recognition Award (one-time) (瞪羚企业直接认定奖励(一次性))          Fiscal appropriation               0       50,000.00 Other income Related to income
      Special subsidy for research and development expenses of gazelle enterprises
                                                                                                       Fiscal appropriation               0      500,000.00 Other income Related to income
      (瞪羚企业研发费专项补助)
      Recruitment of social insurance subsidies for non-employment diculties in 2021
                                                                                                       Fiscal appropriation               0      122,726.92 Other income Related to income
      (2021年招用非就业困难社会保险补贴)
      Venue Subsidy of Guangzhou entrepreneurship leading team in 2020
                                                                                                       Fiscal appropriation               0      278,460.00 Other income Related to income
      (广州市创业领军团队2020年场地补贴)
      2019 SME subsidies(2019年中小开补贴)                                                           Fiscal appropriation               0      107,500.00 Other income Related to income
      Export credit insurance subsidy in the second half of 2019(2019年下半年出口信保补贴资金)       Fiscal appropriation               0      304,900.00 Other income Related to income
      Subsidy for the second batch of patent applications in Shenzhen in 2018
                                                                                                       Fiscal appropriation        8,000.00               0 Other income Related to income
      (2018年深圳第二批专利申请资助款)
      The rst batch of enterprise research and development funding plan in 2019
                                                                                                       Fiscal appropriation     806,000.00                0 Other income Related to income
      (2019年度企业研究开发资助计划第一批)
      Support for further steady growth in 2019 (2019年进一步稳增长资助)                               Fiscal appropriation     400,000.00                0 Other income Related to income
      The 20th China Patent Award (第二十届中国专利奖)                                                 Fiscal appropriation     200,000.00                0 Other income Related to income
      Pre-job training subsidy (岗前培训补贴)                                                          Fiscal appropriation        6,200.00        9,200.00 Other income Related to income
      bone and joint repair and health care (骨关节修复与保健)                                         Fiscal appropriation     119,706.80       119,706.24 Other income Related to assets
      Funding for the integration of industrialization and industrialization (两化融合资助款)          Fiscal appropriation       50,000.00               0 Other income Related to income
      Nanshan District Science and Technology Award Support Program (2019)
                                                                                                       Fiscal appropriation     200,000.00                0 Other income Related to income
      (南山区科技奖励支持计划(2019年))
      Nanshan District Enterprise R&D Investment Support Plan (2019)
                                                                                                       Fiscal appropriation     658,500.00                0 Other income Related to income
      (南山区企业研发投入支持计划(2019年))
      Nanshan District Patent Support Program (2019) (南山区专利支持计划(2019年))                    Fiscal appropriation       28,500.00        5,000.00 Other income Related to income
      Shenzhen Economic and Trade Bureau Electricity Cost Reduction Subsidy
                                                                                                       Fiscal appropriation    1,421,280.76               0 Other income Related to income
      (深圳经贸局用电降成本补助)
      Unemployment Insurance Rebate (失业保险返还款)                                                   Fiscal appropriation     750,931.65                0 Other income Related to income
      Sewage treatment fee subsidy (污水处理费补贴)                                                    Fiscal appropriation       74,884.95               0 Other income Related to income
      Return of land transfer fee (土地出让金返还)                                                     Fiscal appropriation       56,397.36               0 Other income Related to assets
      Invention patent maintenance awards for more than 6 years (Science and Technology Bureau of
      Xinxiang High-tech District Management Committee)                                                Fiscal appropriation        4,400.00               0 Other income Related to income
      (6年以上发明专利维护奖补(新乡高新区管委会科学技术局))




244
                                                                                                                                                                     Annual Report
                                                                                                                                                                             2021


                                                                                                                                     Amount           Amount
                                                                                                                                                               Presentation
                                                                                                                                   charged to      charged to                 Related to assets/
 Projects with grants                                                                                          Type                                            item in prot
                                                                                                                               prot and loss    prot and loss                 income
                                                                                                                                                               and loss
                                                                                                                                for Last Year     for the Year
 Invention Patent Authorization Award (Xinxiang High-tech District Science and Technology Bureau)
                                                                                                        Fiscal appropriation       16,000.00               0 Other income Related to income
 (发明专利授权奖补(新乡高新区管委会科学技术局))
 Provincial R&D Platform Certication Award Supplement (Xinxiang High-tech District Science and
                                                                                                        Fiscal appropriation     100,000.00                0 Other income Related to income
 Technology Bureau) (省级研发平台认定奖补(新乡高新区管委会科学技术局))
 Enterprise R&D Subsidy Fund (Xinxiang High-tech District Science and Technology Bureau)
                                                                                                        Fiscal appropriation     560,000.00                0 Other income Related to income
 (企业研发费补贴资金(新乡高新区管委会科学技术局))
 2019 Special Fund for Cross-border E-commerce Comprehensive Pilot Zone (Service Industry
 Promotion Bureau of Xinxiang High-tech District Management Committee)                                  Fiscal appropriation        1,400.00               0 Other income Related to income
 (2019年跨境电商综合实验区专项资金(新乡高新区管委会服务业促进局))
 High-tech District Promotion Bureau Henan Province Investment Promotion Incentive Fund
                                                                                                        Fiscal appropriation     750,000.00                0 Other income Related to income
 (高新区促进局河南省招商引资奖励资金)
 High-tech District Promotion Bureau platform online funding subsidy
                                                                                                        Fiscal appropriation       40,000.00               0 Other income Related to income
 (高新区促进局平台上线资金补贴)
 2020 Xinxiang major science and technology special fund of High-tech District Science and
                                                                                                        Fiscal appropriation     400,000.00                0 Other income Related to income
 Technology Bureau (高新区科技局2020年度新乡市重大科技专项资金)
 The third batch of special funds for provincial science and technology basic conditions of High-tech
                                                                                                        Fiscal appropriation       40,000.00               0 Other income Related to income
 District Science and Technology Bureau (高新区科技局三批省科技基础条件专项经费)
 Inland Revenue Department refunds overpaid stamp duty (税务局退多交印花税)                             Fiscal appropriation       20,000.00               0 Other income Related to income
 Special funds for corporate R&D nancial subsidies in 2020(2020年企业研发财政补助专项资金) Fiscal appropriation                          0      265,000.00 Other income Related to income
 Land Support Fund in 2020 (2020土地扶持资金)                                                           Fiscal appropriation               0       56,397.36 Other income Related to assets
 Job stabilization subsidy in 2020 (Xinxiang Unemployment Insurance Management Center)
                                                                                                        Fiscal appropriation       77,116.86       15,006.57 Other income Related to income
 2020年稳岗补贴(新乡失业保险管理中心)
 2020 Provincial Foreign Economic and Trade Development Special Fund (Xinxiang High-tech
 District Management Committee Service Industry Promotion Bureau)                                       Fiscal appropriation        8,000.00               0 Other income Related to income
 (2020年省级外经贸发展专项资金(新乡高新区管委会服务业促进局)
 Export credit insurance subsidy (Xinxiang High-tech District Management Committee Service
                                                                                                        Fiscal appropriation       24,400.00               0 Other income Related to income
 Industry Promotion Bureau) (出口信保补贴(新乡高新区管委会服务业促进局))
 Subsidies for work-based training(以工代训补助)                                                      Fiscal appropriation       20,500.00               0 Other income Related to income
 Special Subsidies for Epidemic Support Enterprises (疫情支持企业专项资助)                              Fiscal appropriation       10,300.00               0 Other income Related to income
 One-time subsidy for enterprises to absorb and le poor laborers
                                                                                                        Fiscal appropriation               0        5,000.00 Other income Related to income
 (企业吸纳建档立卡贫困劳动力就业一次性补贴)
 The second batch of funding plans for technological transformation investment projects in 2021
                                                                                                        Fiscal appropriation               0    1,710,000.00 Other income Related to income
 (2021年技术改造投资项目第二批资助计划)
 Science and Technology Innovation Special Fund Government Subsidy-Shenzhen Pingshan District
 Science and Technology Innovation Bureau                                                               Fiscal appropriation               0    1,085,794.00 Other income Related to income
 (科技创新专项资金政府补助-深圳市坪山区科技创新局)
 Subsidies for work-based training(以工代训)                                                          Fiscal appropriation               0        2,000.00 Other income Related to income
 Export credit insurance subsidy (出口信保补贴)                                                         Fiscal appropriation    2,410,489.14    1,991,489.70 Other income Related to income
 R&D subsidy(研究开发费补助)                                                                          Fiscal appropriation    6,331,169.33    6,267,222.00 Other income Related to income
 Research and development funds for new drug for Class I Treatment of Necrosis Factor in Human
 Tumour from Human Source                                                                               Fiscal appropriation   -8,000,000.00               0 Other income Related to income
 (I类治疗用人源化抗人肿瘤坏死因子α单克隆抗体新药的研制资金)
  Government Subsidy for Long-acting Microspheres Major New Drug Creation
                                                                                                        Fiscal appropriation    1,206,390.00               0 Other income Related to income
(长效微球重大新药创制政府补助)
  Government Subsidy for Long-acting Microspheres Major New Drug Creation
                                                                                                        Fiscal appropriation     828,374.15     4,784,320.37 Other income Related to assets
(长效微球重大新药创制政府补助)
 R&D and industrialization of innovative Ilaprazole series(艾普拉唑系列创新药物研发及产业化) Fiscal appropriation             4,910,000.04    4,910,000.04 Other income Related to assets
 R&D and industrialization of innovative Ilaprazole series(艾普拉唑系列创新药物研发及产业化) Fiscal appropriation              748,129.50       560,000.00 Other income Related to income




                                                                                                                                                                                            245
                                                                                                                                       Amount           Amount
                                                                                                                                                                 Presentation
                                                                                                                                     charged to      charged to                 Related to assets/
       Projects with grants                                                                                     Type                                             item in prot
                                                                                                                                 prot and loss    prot and loss                 income
                                                                                                                                                                 and loss
                                                                                                                                  for Last Year     for the Year
        Construction of Drug Conformity Evaluation Research Center Platform
                                                                                                         Fiscal appropriation      159,999.96       159,999.96 Other income Related to assets
      (药物一致性评价研究中心平台建设)
       Conformity Evaluation Research of Quality of Varieties such as Livzon Dele
                                                                                                         Fiscal appropriation      231,000.00       231,000.00 Other income Related to assets
      (丽珠得乐等品种质量一致性评价研究)
       Internet Benchmarking Project for Advanced Drug Manufacturing(先进药品制造互联网标杆项目) Fiscal appropriation              90,000.00       90,000.00 Other income Related to assets
      R&D and commercialisation of Recombinant Human Chorionic Gonadotropin for Injection
                                                                                                         Fiscal appropriation      150,000.00       150,000.00 Other income Related to assets
      (注射用重组人绒促性素研发及产业化)
       Construction of HCG Project(HCG项目建设)                                                        Fiscal appropriation      161,921.69       395,649.97 Other income Related to assets
       Fiscal Subsidy and Operating Subsidy(财政补贴及经营运营补贴)                                    Fiscal appropriation   119,079,372.24 119,047,484.00 Other income Related to income
        R&D and Commercialisation of Mouse Nerve Growth Factor for Injection
                                                                                                         Fiscal appropriation   10,560,089.16     10,560,089.27 Other income Related to assets
      (注射用鼠神经生长因子研发及产业化)
        Capital projects of innovation and entrepreneurship team funding program
                                                                                                         Fiscal appropriation     2,500,000.00               0 Other income Related to income
      (创新创业团队资助计划资金项目)
       Provincial Science and Technology Innovation Strategy Special Fund(省科技创新战略专项资金)      Fiscal appropriation     1,500,000.00      473,166.56 Other income Related to assets
       Project of astragalus base(黄芪基地项目)                                                        Fiscal appropriation     4,641,357.94               0 Other income Related to assets
       Promoting Imports of Foreign Trade Development Special Fund(外贸经济发展专项资金)               Fiscal appropriation      697,650.00        50,352.00 Other income Related to income
       Production safety subsidy(安全生产补助)                                                         Fiscal appropriation        62,000.00               0 Other income Related to income
      Subsidy for Rental and Property Fee of the Investment and Promotion Center
                                                                                                         Fiscal appropriation                0       67,500.00 Other income Related to income
      (投促中心租金及物业费补贴)
       Technological Upgrading and Transformation Projects of Workshop for Acarbose (API of Glucosidase
                                                                                                        Fiscal appropriation       107,142.84       107,142.84 Other income Related to assets
       Inhibitor) (α-葡萄糖苷酶抑制剂类原料药阿卡波糖生产车间工艺升级技术改造项目)
       Subsidy for the Tender of Technology Upgrade Project for PVC Soft Bag Supported by Provincial
                                                                                                         Fiscal appropriation      194,365.80       408,365.76 Other income Related to assets
       Finance Departments (省财政支持技改招标项目补助金PVC软袋)
       Technical transformation project of Shenqi Fuzheng Injection with exible bag
                                                                                                         Fiscal appropriation     1,213,999.92     3,823,529.40 Other income Related to assets
       (软袋参芪扶正注射液技改项目)
       Financial grant for the quality control technologies of Shenqi (参芪质量控制技术财政拨款)         Fiscal appropriation     2,823,529.44               0 Other income Related to assets
       Demonstration project on the application of solar photovoltaic architecture
                                                                                                         Fiscal appropriation     1,102,000.08     1,102,000.08 Other income Related to assets
       (太阳能光电建筑应用示范项目)
       Electricity Incentive Funds (用电奖励资金)                                                        Fiscal appropriation      217,903.00       364,257.43 Other income Related to income
       Subsidies for high and new technology enterprises and high and new technology products
                                                                                                         Fiscal appropriation      504,000.00      1,071,346.00 Other income Related to income
       (高新技术企业及高新技术产品项目补贴)
       Grants to high-growth technology companies from Dazhangjiang project A04
                                                                                                         Fiscal appropriation                0     1,500,000.00 Other income Related to income
       (大张江项目A04对高增长技术企业资助款)
       Small and medium enterprise market development project funds (中小企业开拓市场项目资金)           Fiscal appropriation        33,135.00               0 Other income Related to income
       Provision for technology transformation funds and subsequent grants
                                                                                                         Fiscal appropriation      335,100.00      1,576,000.00 Other income Related to income
       (技术改造资金拨款及事后补奖)
       Provision for technology transformation funds and subsequent grants
                                                                                                         Fiscal appropriation     3,687,744.59     4,131,600.00 Other income Related to assets
       (技术改造资金拨款及事后补奖)
       R&D and commercialisation of Statins (降血脂他汀类药物的研发与产业化)                             Fiscal appropriation        29,999.88       29,999.88 Other income Related to assets
       Technology transformation of recycling system of Acarbose project
                                                                                                         Fiscal appropriation     1,239,575.06      397,818.48 Other income Related to assets
       (阿卡波糖糖回收系统技术改造项目)
       Commissioner workstation (特派员工作站)                                                           Fiscal appropriation        60,000.00       60,000.00 Other income Related to assets
       Special Fund and Encouraging funds for Energy Saving and Emission Reduction
                                                                                                         Fiscal appropriation        50,000.00      352,000.00 Other income Related to income
       (节能减排专项资金及奖励金)
       Energy-saving and emission reduction projects (节能减排项目)                                      Fiscal appropriation        12,030.04       86,030.04 Other income Related to assets
       Scientic technology award and subsidy for technological innovative project
                                                                                                         Fiscal appropriation     4,027,272.76     7,352,000.00 Other income Related to income
       (科学技术奖及科技创新项目资助)




246
                                                                                                                                                                Annual Report
                                                                                                                                                                        2021


                                                                                                                                Amount           Amount
                                                                                                                                                          Presentation
                                                                                                                              charged to      charged to                 Related to assets/
 Projects with grants                                                                                     Type                                            item in prot
                                                                                                                          prot and loss    prot and loss                 income
                                                                                                                                                          and loss
                                                                                                                           for Last Year     for the Year
 Scientic technology award and subsidy for technological innovative project
                                                                                                   Fiscal appropriation               0      250,000.00 Other income Related to assets
 (科学技术奖及科技创新项目资助)
 Set-up and research fund for postdoctoral Station (博士后建站和科研补贴)                          Fiscal appropriation     500,000.00       100,000.00 Other income Related to income
 Patent (Intellectual Property) Support Fund (专利(知识产权)资助资金)                            Fiscal appropriation    2,055,068.00      849,370.00 Other income Related to income
 Optimization of structural eect of sea organisms and valuation of anti-tumor activity
                                                                                                   Fiscal appropriation               0       12,307.34 Other income Related to income
 (海洋微生物构效优化与抗肿瘤活性评价)
 Policy fund for leading industrial enterprises loan interests (工业龙头企业贷款贴息政策资金)      Fiscal appropriation     200,000.00       200,000.04 Other income Related to assets
 Government grant for industrial transformation (工业转型政府扶持资金)                             Fiscal appropriation     199,999.92       199,999.92 Other income Related to assets
 Reward Fund for Industry Growth and Production Expansion (工业保值增长及增产奖励)                 Fiscal appropriation   27,794,500.00    5,050,000.00 Other income Related to income
 New industrialization development funds (新型工业化发展资金)                                      Fiscal appropriation     300,000.04       350,000.04 Other income Related to assets
 Industrial revitalisation supporting funds (产业振兴扶持资金)                                     Fiscal appropriation    1,158,000.00    1,158,000.00 Other income Related to assets
 Industrial supporting funds(产业扶持资金)                                                       Fiscal appropriation               0       13,000.00 Other income Related to income
 Supporting funds for ve advantageous industrial clusters and one high-tech industry
                                                                                                   Fiscal appropriation     150,000.00        99,999.96 Other income Related to assets
 (五优一新扶持资金)
 Employment Assurance and Re-employment and Attraction to Graduates of Tertiary Academic
                                                                                                   Fiscal appropriation    5,760,396.73    5,024,018.69 Other income Related to income
 Institutions Subsidy (企业稳岗及再就业和吸纳高校毕业生补贴款)
 New Scientic Research Institution Subsidy (新型科研机构补助资金)                                  Fiscal appropriation               0    2,000,000.00 Other income Related to assets
 Enterprise Technology Center Innovation Capacity Development (Antibody Laboratory)
                                                                                                   Fiscal appropriation   -3,179,362.63      445,755.36 Other income Related to assets
 (企业技术中心创新能力建设(抗体药物试验室))
 Enterprise Technology Center Innovation Capacity Development (Antibody Laboratory)
                                                                                                   Fiscal appropriation       86,916.30       75,330.36 Other income Related to income
 (企业技术中心创新能力建设(抗体药物试验室))
 Special funds for industry and informatization (工业和信息化专项资金)                             Fiscal appropriation               0       48,000.00 Other income Related to income
 Supporting subsidy for“Talents Plan”and subsidy for talents introduction and cultivation
                                                                                                   Fiscal appropriation               0      646,759.03 Other income Related to income
 (“人才计划”配套补贴及引才育才补贴)
 Bounties for import and export growth to BRICS countries (对金砖国家进出口增长奖励金)             Fiscal appropriation    1,011,750.00               0 Other income Related to income
 Incentive funds for expansion of export scale (扩大出口规模奖励基金)                              Fiscal appropriation     389,300.00       519,700.00 Other income Related to income
 Subsidy for online monitoring equipment for coalred boilers (燃煤锅炉在线监控设备装置补助)        Fiscal appropriation       22,500.00       22,500.00 Other income Related to assets
 Special funds for key leading enterprises in the 13th Five-Year Plan (2019)
                                                                                                   Fiscal appropriation    4,784,100.00               0 Other income Related to income
 (十三五重点领军企业专项资金(2019年))
 Green factory (绿色工厂)                                                                          Fiscal appropriation       48,333.29      129,999.96 Other income Related to assets
 Special capital replenishment for industrial enterprise Restructuring
                                                                                                   Fiscal appropriation    1,940,000.00      130,000.00 Other income Related to income
 (工业企业结构调整专项资补资)
 National Key R&D Program“Network Collaborative Manufacturing and Smart Factory”Special
                                                                                                   Fiscal appropriation     610,000.00                0 Other income Related to income
 Project (国家重点研发计划”网络协同制造和智能工厂”专项)
 Research on transformation of bacterial strains and fermentation process
                                                                                                   Fiscal appropriation     480,000.00       160,000.00 Other income Related to income
 (菌种改造与发酵工艺研究)
 Network reconstruction and system optimization of actinomycete drug synthesis biological system
                                                                                                   Fiscal appropriation    1,170,000.00               0 Other income Related to income
 (放线菌药物合成生物体系的网络重构与系统优化)
 Refund of unemployment insurance fees (失业保险费返还款)                                          Fiscal appropriation    2,067,505.76       29,476.67 Other income Related to income
 Subsidies for work-based training(以工代训)                                                     Fiscal appropriation     901,700.00       848,400.00 Other income Related to income
 Subsidies for insurance fees (保险费用补贴)                                                       Fiscal appropriation     478,471.45       200,000.00 Other income Related to income
 Subsidies and supporting funds for production of emergency materials in Xiangzhou District
                                                                                                   Fiscal appropriation     200,000.00         1,000.00 Other income Related to income
 (香洲区应急物资生产补贴扶持资金)
  Subsidies and supporting funds for production of emergency materials in Xiangzhou District
                                                                                                   Fiscal appropriation        1,044.25        2,088.50 Other income Related to assets
(香洲区应急物资生产补贴扶持资金)
 Special Funds for Promoting High-quality Economic Development(促进经济高质量发展专项资金) Fiscal appropriation                     0      357,200.00 Other income Related to assets
 Special Funds for Promoting High-quality Economic Development(促进经济高质量发展专项资金) Fiscal appropriation           476,266.67     3,540,020.00 Other income Related to income



                                                                                                                                                                                       247
                                                                                                                                                Amount           Amount
                                                                                                                                                                          Presentation
                                                                                                                                              charged to      charged to                 Related to assets/
       Projects with grants                                                                                              Type                                             item in prot
                                                                                                                                          prot and loss    prot and loss                 income
                                                                                                                                                                          and loss
                                                                                                                                           for Last Year     for the Year
       Funds for projects of proactively expanding import in Zhuhai(珠海市主动扩大进口项目资金)                 Fiscal appropriation      133,505.00                0 Other income Related to income
       Special funds for expenditures in respect of projects for other causes including people's livelihood for
                                                                                                                  Fiscal appropriation      200,000.00                0 Other income Related to income
       2020 (Silver Age Project) (20年民生补助等其他事业性发展支出(银龄专项)项目资金)
       Funds for joint R&D and industrialization of integrated platform for molecular diagnostics
                                                                                                                  Fiscal appropriation      865,100.00     1,368,367.87 Other income Related to assets
       (集成一体化分子诊断平台的合作研发及产业化)
       Research of high-throughput screening technology for toxic substances in aquatic products
                                                                                                                  Fiscal appropriation        80,000.00               0 Other income Related to income
       (水产品中有害物质高通量检测技术研究)
       Employment tax incentives for key groups and retired soldiers (重点群体及退役士兵就业税收优惠) Fiscal appropriation                            0       66,400.00 Other income Related to income
       Funds for industrial volatile organic pollution control projects (工业挥发性有机污染治理项目资金) Fiscal appropriation                         0      628,000.00 Other income Related to income
       Achievement transfer of blood screening BCI nucleic acid detection testing
                                                                                                                  Fiscal appropriation                0    2,038,717.57 Other income Related to assets
       (血液筛查BCI核酸检测试剂成果转化)
       COVID-19 emergency technology special emergency fund and special grants for industrialization
                                                                                                                  Fiscal appropriation                0    1,084,784.35 Other income Related to assets
       (新冠应急科技攻关专项款及产业化项目补助金)
      “Specialized and new”subsidy (“专精特新”补贴)                                                           Fiscal appropriation                0      175,000.00 Other income Related to income
       Exchange rate hedging subsidy (汇率避险补贴)                                                               Fiscal appropriation                0      106,605.00 Other income Related to income
       National foreign special fund for 2020 allocated by Guangdong Province Science and Technology
                                                                                                                  Fiscal appropriation                0      300,000.00 Other income Related to income
       Department (广东省科学技术厅拨来2020年度国家外专款)
       Several measures to pay enterprises to tide over diculties in response to COVID-19 pandemic –
       funds for nancial support project                                                                          Fiscal appropriation                0    6,093,000.00 Other income Related to income
       (应对新型冠状病毒肺炎疫情支付企业共渡难关的若干措施-金融支持项目资金)
       Others                                                                                                     Fiscal appropriation      258,657.39        68,848.09 Other income Related to income
       Total                                                                                                                             246,262,917.95 245,335,140.69



VI. Change to Consolidation Scope

 1. Business combination not involving enterprises under common control
      □ Applicable √ N/A


 2. Business combination involving enterprises under common control
      □ Applicable √ N/A


 3. Reverse purchase
      □ Applicable √ N/A




248
                                                                                                                         Annual Report
                                                                                                                                 2021


4. Disposal of subsidiaries
    Was there any circumstance under which a single disposal of the investment in subsidiaries will lose control
    √ Applicable □ N/A
                                                                                                                   Unit: Yuan Currency: RMB
                                                                                                                 Dierences arising from
                                   Amount of                              Time of         Recognisation       disposal amount and portion
                                                   Disposal Mode of
     Name of subsidiary            disposal for                           ceased          for the time of    of net assets held by disposal
                                                    ratio% disposal
                                      equity                              control         ceased control       investment for the range of
                                                                                                            consolidated nancial statement
     Zhuhai Qiao Biotechnology
     Co., Ltd. ( 珠海启奥生物技   10,000,000.00       60       Sale       2021.6.11       Asset delivery             2,423,029.20
     术有限公司 )


    Continued:


                                  Percentage      Book value   Fair value                      Recognisation         Prot or loss
                                      of the          of the      of the                          and major          arising from
                                                                                Gain/loss
                                  remaining       remaining    remaining                      assumptions for     transformation of
                                                                               arising from
     Name of subsidiary            equity at       equity at    equity at                     fair value of the other comprehensive
                                                                             remeasurement
                                    the date        the date    the date                     remaining equity      income which is
                                                                               at fair value
                                   of ceased       of ceased   of ceased                        at the date of     related to equity
                                     control         control     control                       ceased control         investment
     Zhuhai Qiao Biotechnology
     Co., Ltd.( 珠海启奥生物技         -              -               -               -                     -                   -
     术有限公司 )


    Other descriptions:
    □ Applicable √ N/A


5. Changes in scope of consolidation due to other reasons
    Descriptions of changes in scope of consolidation caused by other reasons (such as establishment of a new subsidiary and
    liquidation of a subsidiary, etc.) and their relevant information:
    √ Applicable □ N/A

(1). On 30 March 2021, the Livzon Group and Shanghai Frontier Health Pharmaceutical Technology Co., Ltd. ( 上 海 方 予 健 康 医
     药科技有限公司 ) established Shanghai Liyu Biotechnology Co., Ltd. ( 上海丽予生物医药有限责任公司 ) with a registered
     capital of RMB 3 million, of which Livzon Group contributed RMB 1.65 million and is interested in 55% of its registered
     capital, and Shanghai Frontier contributed RMB 0.81 million and is interested in 45% of its registered capital.

(2). On 9 February 2021, Zhuhai Livzon Diagnostics Inc. ( 珠 海 丽 珠 试 剂 股 份 有 限 公 司 ), a subsidiary of Livzon Group,
    established Zhuhai Liye Biotechnology Co., Ltd. ( 珠 海 市 丽 业 生 物 技 术 有 限 公 司 ) with a registered capital of RMB50
    million, and is interested in 100% of its registered capital. On 13 August 2021, Zhuhai Livzon Diagnostics Inc. ( 珠 海 丽 珠 试
    剂股份有限公司 ) established Changsha Lijin Baokang Medical Technology Co., Ltd. ( 长沙丽瑾葆康医疗科技有限公司 )
    with a registered capital of RMB1 million, and is interested in 100% of its registered capital.

(3). On 25 May 2021, Fuzhou Fuxing Pharmaceutical Co. Ltd. ( 福 州 市 福 兴 制 药 有 限 公 司 ), a subsidiary of Livzon Group,
     completed deregistration at the Administration for Industry and Commerce. On 31 December 2021, Both of Livzon
     International Limited and Livzon Biologics Limited, subsidiaries of Livzon Group, completed deregistration.




                                                                                                                                        249
VII EQUITY IN OTHER ENTITIES

 1. Equity in subsidiaries
(1). Group structure
     √ Applicable □ N/A


                                                                      Principal                                     Percentage of
                                                                                     Place of         Nature of
       Name of subsidiary                                             Place of                                     Shareholding (%)              Acquisition Method
                                                                                     Registration     Business
                                                                      Business                                     Direct   Indirect
       Topsino Industries Limited                                     Hong Kong      Hong Kong        Business       100             0                 Set-up
       Shenzhen Taitai Genomics Inc. Co., Ltd.                        Shenzhen       Shenzhen         Industry        75            25                 Set-up
       Shenzhen Taitai Pharmaceutical Industry Co., Ltd.              Shenzhen       Shenzhen         Industry       100             0                 Set-up
       Health Investment Holdings Ltd.                                The British    The British
                                                                                                      Investment       0        100                    Set-up
       (Health Investment)                                            Virgin Islands Virgin Islands
                                                                      The British    The British
       Joincare Pharmaceutical Group Industry Co.,Ltd.(BVI)*                                          Investment       0        100                    Set-up
                                                                      Virgin Islands Virgin Islands
       Joincare Pharmaceutical Group Industry Co., Ltd.
                                                                      Cayman         Cayman           Investment       0        100                    Set-up
       (CAYMAN ISLANDS)
       Zhuhai Jiankangyuan Biology Medicine Co., Ltd. Note 1          Zhuhai         Zhuhai           Industry     90.89             0                 Set-up
       Xinxiang Haibin Pharmaceutical Co., Ltd.(Xinxiang Haibin) Xinxiang          Xinxiang         Industry         0        100                    Set-up
       Shenzhen Fenglei Electric Power Investment Co., Ltd.
                                                                      Shenzhen       Shenzhen         Investment     100             0                 Set-up
      (Fenglei Electric Power)
       Jiaozuo Joincare Bio Technological Co., Ltd.
                                                                      Jiaozuo        Jiaozuo          Industry        75            25                 Set-up
      (Jiaozuo Joincare)
       Shanghai Frontier Health Pharmaceutical Technology Co., Ltd.
                                                                      Shanghai       Shanghai         Industry        65             0                 Set-up
      (Shanghai Frontier)Note 2
       Shenzhen Taitai Biological Technology Co., Ltd. (Taitai
                                                                      Shenzhen       Shenzhen         Industry       100             0                 Set-up
       Biological)
       Guangzhou Joincare Respiratory Medicine Engineering
                                                                      Guangzhou      Guangzhou        Industry         0            26                 Set-up
       Technology Co., Ltd.(Joincare Respiratory)
       Guangdong Taitai Forenstic Test Institute                      Shenzhen       Shenzhen         Business         0        100                    Set-up
       Joincare Haibin Pharmaceutical Co., Ltd.                       Shenzhen       Shenzhen         Industry        25            75                 Set-up
       Shenzhen Haibin Pharmaceutical Co., Ltd.                       Shenzhen       Shenzhen         Industry     97.87       2.13 Consolidation not under common control
       Joincare Daily-Use & Health Care Co., Ltd.                     Shenzhen       Shenzhen         Business        80            20 Consolidation not under common control
       Health Pharmaceuticals (China) Limited                         Zhuhai         Zhuhai           Industry         0        100 Consolidation not under common control
       Livzon Pharmaceutical Group Inc. (Livzon Group) Note 3         Zhuhai         Zhuhai           Industry     23.69      21.14 Consolidation not under common control
       Hong Kong Health Pharmaceutical Industry Company Limited Hong Kong            Hong Kong        Investment       0        100 Consolidation not under common control
       Health Pharmaceutical Industry Company Limited                 Hong Kong      Hong Kong        Investment       0        100 Consolidation not under common control
       Shenzhen Hiyeah Industry Co., Ltd.                             Shenzhen       Shenzhen         Business     97.58       2.42 Consolidation not under common control
       Guangzhou Hiyeah Industry Co., Ltd.                            Guangzhou      Guangzhou        Industry         0        100 Consolidation not under common control
       Zhongshan Renhe Health Products Co., Ltd.                      Zhongshan      Zhongshan        Industry         0        100 Consolidation not under common control
       Shenzhen Jiekang Health Care Co., Ltd.                         Shenzhen       Shenzhen         Industry         0        100 Consolidation not under common control
       Joincare (Guangdong) Special medicine Food Co., Ltd.           Shaoguan       Shaoguan         Industry       100             0                 Set-up
       Henan Joincare Biomedical Research Institute Co., Ltd. Note 4 Jiaozuo         Jiaozuo          Industry         0      70.14                    Set-up




250
                                                                                                                  Annual Report
                                                                                                                          2021


    Other descriptions:
    Noe 1: On 8 September 2021, Zhuhai Jiankangyuan Biology Medicine Co., Ltd. completed the cancellation of the business
            license.
    Note 2: On 30 March 2021, Shanghai Frontier Health Pharmaceutical Technology Co., Ltd. ( 上 海 方 予 健 康 医 药 科 技 有 限
            公 司 ) and the Livzon Group, a subsidiary of the Company, established Shanghai Liyu Biotechnology Co., Ltd. ( 上
            海丽予生物医药有限责任公司 ), of which Livzon Group is interested in 55% of its registered capital, and Shanghai
            Frontier interested in 45% of its registered capital.
    Note 3: Zhuhai Livzon Biomedical Technology Co., Ltd. was a subsidiary within the scope of Livzon Group's consolidation.
            It was originally 100% indirectly held by Livzon Group. In this period, due to the restructuring of the shareholding
            structure of Livzon Group's holding subsidiary, it was adjusted to Livzon Group holding 55.13% of the shares, the
            company holding 35.75% of the shares, and YF Pharmab Limited holding 9.12% of the shares.

    Note 4: On 26 October 2020, Jiaozuo Joincare Bio Technological Co., Ltd. (a subsidiary of the Company) and Livzon
            Xinbeijiang Pharmaceutical Co., Ltd. (a subsidiary of the Company's subsidiary Livzon Group) co-founded Henan
            Joincare Biomedical Research Institute Co., Ltd., in which, the former holding 51% of the shares. The joint venture
            completed the business registration on 26 October 2020.

    Subsidiaries not included in the scope of consolidation in the current period:


     Name of subsidiary                                     Registered Capital             Actual investment            Own interest
     Guangzhou Hiyeah Industry Co., Ltd.                          3,000,000.00                   3,000,000.00                  100%
     Zhongshan Renhe Health Products Co., Ltd.                      500,000.00                     500,000.00                  100%
     Shenzhen Jiekang Health Care Co., Ltd.                       4,000,000.00                   4,000,000.00                  100%


    Guangzhou Hiyeah Industry Co., Ltd., Zhongshan Renhe Health Products Co., Ltd., and Shenzhen Jiekang Health Care Co.,
    Ltd. are wholly-owned subsidiaries of Hiyeah Industry. They entered the liquidation process in 2008. They have been closed
    for many years and completed the tax cancellation procedures. So they are not included in the scope of the consolidated
    statement.

(2). Important non-wholly owned subsidiaries
     √ Applicable □ N/A
                                                                                                             Unit: Yuan Currency: RMB
                                                       Gain or loss for the      Dividends distributed to        Balance of minority
                                 Percentage of
     Name of subsidiary                               Period attributable to     the minority interest for      interest at the End of
                               minority interest
                                                          minority interest                    the Period                   the Period
     Livzon Group                    55.1743%              977,852,785.18                644,923,997.09            7,174,735,557.32


    Descriptions of the dierence between the shareholding ratio of minority shareholders and their
    proportion of voting rights in a subsidiary:
    □ Applicable √ N/A

    Other descriptions:
    □ Applicable √ N/A




                                                                                                                                  251
(3). Important non-wholly owned subsidiaries
     √ Applicable □ N/A
                                                                                                              Unit: 10,000 Yuan Currency: RMB
                                                                Balance at the End of the Period
      Name of
                                                 Non-current                                Current           Non-current
      subsidiary             Current assets                        Total assets                                               Total liabilities
                                                      assets                              liabilities           liabilities
      Livzon Group           1,467,309.66         769,881.90      2,237,191.56           692,506.81            113,582.27         806,089.08
                                                             Balance at the Beginning of the Period
      Name of
                                                 Non-current                                Current           Non-current
      subsidiary             Current assets                        Total assets                                               Total liabilities
                                                      assets                              liabilities           liabilities
      Livzon Group           1,462,735.70         596,345.88      2,059,081.58           608,288.89             86,784.49         695,073.38

      Name of                                                       Amount for the Period
      subsidiary                  Revenue          Net prot      Total Comprehensive income             Cash ow from operating activities
      Livzon Group           1,206,386.33         195,210.12                       183,489.81                                     190,232.81
      Name of                                                   Amount for the Previous Period
      subsidiary                  Revenue          Net prot      Total Comprehensive income             Cash ow from operating activities
      Livzon Group           1,052,040.98         213,132.67                       227,271.22                                     216,076.06

(4). Signicant restrictions on the use of enterprise group assets and settlement of enterprise
     group debts:
     □ Applicable √ N/A

(5). Financial supports or other supports oered for the structured entities included in the
     scope of consolidated nancial statements:
     □ Applicable √ N/A

      Other descriptions:
      □ Applicable √ N/A


 2. Transactions that Result in Change of Owners' Equity in Subsidiaries without Losing Control
      □ Applicable √ N/A


 3. Interests in joint ventures or associates
     √ Applicable □ N/A
(1). Signicant joint ventures or associates
     √ Applicable □ N/A
                                                                                                                    Unit: Yuan Currency: RMB
                        Main                                                              Shareholding(%)    Accounting treatment
      Name of
                        business     Place of registration     Business nature                               of investment in joint
      subsidiary                                                                           Direct Indirect
                        place                                                                              ventures or joint ventures
                      Jiaozuo        Zhaozhanggong Village,    Electricity production,
      Jiaozuo Jinguan
                      City,          Daiwang Town, Macun       power supply,
      Jiahua Electric                                                                       0.00         49             Equity method
                      Henan          District, Jiaozuo City,   comprehensive
      Power Co., Ltd.
                      Province       Henan Province            utilisation of y ash


(2). Key nancial information of signicant joint ventures
     √ N/A




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(3). Key nancial information of signicant associates
     √ Applicable □ N/A
                                                                                                      Unit: Yuan Currency: RMB
                                                                                 Balance at the End   Balance at the Beginning
                                                                            of the Period / Amount      of the Period / Amount
                                                                                     for the Period    for the Previous Period
                                                                            Jinguan Electric Power     Jinguan Electric Power
     Current assets                                                                900,929,930.10              747,232,522.21
     Of which: cash equivalents                                                    151,817,021.98              174,001,731.35
     Non-current assets                                                            295,290,603.34              319,027,493.06
     Total assets                                                                1,196,220,533.44            1,066,260,015.27
     Current liabilities                                                           621,231,810.54              423,866,168.40
     Non-current liabilities                                                        13,660,568.14               14,902,039.03
     Total liabilities                                                             634,892,378.68              438,768,207.43
     Net asset                                                                     561,328,154.76              627,491,807.84
     Of which: Minority interests                                                             0.00                       0.00
     Total equity attributable to shareholders of the parent company               561,328,154.76              627,491,807.84
     Share of net assets calculated by shareholding ratio                          275,050,795.83              307,470,985.84
     Adjustment items                                                                 9,569,113.18               9,085,381.21
     Goodwill
     Unrealised prot on internal transactions
     Provision for diminution in value
     Others                                                                           9,569,113.18               9,085,381.21
     Book value of equity investment in associates                                 284,619,909.02              316,556,367.05
     Fair value of equity investment in associates with public quotation
     Revenue                                                                       702,123,322.31              714,896,011.60
     Finance expenses                                                               14,968,954.50               10,183,170.92
     Income tax expense                                                             -1,540,629.99               22,033,077.65
     Net prot                                                                      -65,176,444.97               33,227,689.56
     Net prot from discontinued operations
     Other comprehensive income
     Total Comprehensive income                                                    -65,176,444.97               33,227,689.56
     Cash ow from operating activities                                            -135,982,225.15              108,439,599.85
     Dividends received from associates in the current year


(4). Summarized accounting information for other non-important associates
     √ Applicable □ N/A
                                                                                                      Unit: Yuan Currency: RMB
                                                                                 Balance at the End   Balance at the Beginning
                                                                            of the Period / Amount      of the Period / Amount
                                                                                     for the Period    for the Previous Period
     Associates:
     Total carrying amount of investment                                         1,134,729,545.83              311,723,232.68
     Total amount calculated by percentage of shareholding
     net prot                                                                       42,217,479.63                  334,745.24
     other comprehensive income                                                     14,789,928.17                  -40,317.61
     total comprehensive income                                                     57,007,407.80                  294,427.63




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(5). Descriptions of signicant restrictions on the ability of joint ventures or associates to transfer funds to the Company
     □ Applicable √ N/A


VIII Risks Management of Financial Instruments
      √ Applicable □ N/A


      The major nancial instruments of the Company include cash, bills receivable and accounts receivable, other receivables, non-
      current assets due within one year, other current assets, financial assets held for trading, other equity instrument investments,
      long-term receivables, bills payable and accounts payable, other payables, short-term borrowings, financial liabilities held
      for trading, non-current liabilities due within one year, short-term borrowings, bonds payable and long-term payables.. The
      details of these financial instruments are disclosed in the respective notes. The financial risk of these financial instruments
      and nancial management policies used by the Company to minimize the risk are disclosed as below. The management of the
      Company manages and monitors the exposure of these risks to ensure the above risks are controlled in the limited range.


 1. Management objectives and policies of risks
      The operation activities of the Company are subject to various nancial risks: market risks (mainly including foreign exchange
      risks and interest rate risks), credit risks and liquidity risks. The Company formulates an overall risk management plan with
      respect to the unforeseeability of the financial market in order to minimise the potential adverse impacts on the financial
      performance of the Company.

 (1) Foreign exchange risks

      The Company conducts its operation primarily in China. Substantially all of the transactions were denominated and settled in
      Renminbi. However, the Company still has certain imports and exports businesses regarding APIs and diagnostic reagents that
      are settled in U.S. dollar and Japanese Yen. The Company's businesses outside China (mainly in Hong Kong, India, Europe)
      are settled in Hong Kong dollars, U.S. dollar and Eurodollar. In addition, the Company will have foreign currency loans
      according to the operating needs. In respect of the above, the Company still exposes to certain foreign exchange risks. Taking
      into account the foreign exchange risks acceptable by the Company, the Company adopted Derivative instruments to control
      foreign exchange risk. However, as to the foreign exchange risk in loans, the Company shall closely monitor the trend of the
      exchange rate of Renminbi, and timely adjust the extent of borrowings, so as to minimise its risks.

      Financial assets and liabilities in foreign currencies held by the Company expressed in Renminbi are stated below:

 ① 31 December 2021
                                                                                                                       Unit: 1,000 Yuan
      Item                                            HKD item         USD item     Euro item     JPY item    GBP item        MOP item
      Financial assets in foreign currency:
      Monetary funds                                 516,034.78    1,296,568.06        559.42     2,406.62         16.70       1,121.33
      Financial assets held for trading              163,071.45             0.00          0.00         0.00         0.00           0.00
      Accounts receivables                                  0.00     579,062.08      4,493.18          0.00         0.00       2,824.85
      Other receivables                                2,712.73             0.00          0.00         0.00         0.00        461.23
      Other equity instrument investments            480,531.75             0.00          0.00         0.00         0.00          0.00
      Subtotal:                                    1,162,350.71    1,875,630.14      5,052.60     2,406.62         16.70       4,407.41
      Financial liabilities in foreign currency:            0.00            0.00          0.00         0.00         0.00           0.00
      Accounts payables                                     0.00          213.29        40.90          0.00         0.00         11.01
      Other payables                                   2,503.18        16,034.63          0.00         0.00         0.00          0.00
      Subtotal:                                        2,503.18        16,247.92        40.90          0.00         0.00         11.01




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② 31 December 2020
                                                                                                                           Unit: 1,000 Yuan
      Item                                            HKD item          USD item      Euro item     JPY item     GBP item      MOP item
      Financial assets in foreign currency:
      Monetary funds                                 335,766.40     1,086,139.94         644.45          0.00         17.25     1,120.27
      Financial assets held for trading                 5,596.91              0.00         0.00          0.00          0.00          0.00
      Accounts receivables                                   0.00     483,761.81       1,275.65          0.00          0.00     2,335.99
      Other receivables                                 3,042.50           435.46          0.00          0.00          0.00       474.95
      Other equity instrument investments             697,310.50              0.00         0.00          0.00          0.00          0.00
      Subtotal:                                     1,041,716.32    1,570,337.22       1,920.10          0.00         17.25     3,931.21
      Financial liabilities in foreign currency:
      Accounts payables                                      0.00          218.39         45.46      6,688.92          0.00          0.00
      Other payables                                      206.06         7,401.12          0.00          0.00          0.00          0.00
      Subtotal:                                           206.06         7,619.51         45.46      6,688.92          0.00          0.00


     As at 31 December 2021, in respect of the Company’s nancial assets and liabilities denominated in foreign currencies such
     as Hong Kong dollar, U.S. dollar, Euro, Japanese Yen and Macau dollar, should the value of RMB appreciate or depreciate by
     5% against foreign currencies such as Hong Kong dollar, U.S. dollar, Euro, Japanese Yen and Macau dollar, and other factors
     remain unchanged, the Company would be subject to an increase or decrease in prot of approximately RMB 151,553,060 (31
     December 2020: approximately RMB130,168,110).

(2). Interest rate risk

     The Company's exposures to interest rate risk are mainly arising from interest-bearing liabilities such as bank borrowings and
     bonds payables. The interest rates are aected by the macro monetary policies of China, hence the Company will face the risks
     arising from uctuation of interest rates in the future.

     The nance department of the head oce of the Company continues to monitor the level of interest rate of the Company. The
     rise in the interest rate will increase the cost of additional interest-bearing liabilities and the interest expenses of the Company's
     outstanding interest-bearing liabilities of which the interests are calculated at floating rates, and impose material adverse
     impact on the financial results of the Company. The management will make timely adjustment based on the updated market
     conditions. The directors of the Company consider that the future changes in the interest rate will have no material adverse
     impact on the operating results of the Company.

(3). Credit risk

     Credit risk is primarily attributable to cash and cash equivalents, restricted funds, accounts receivables and other receivables.
     In respect of cash at banks, they were placed at several banks with good reputations, for which the credit risk was limited.
     In respect of receivables, the Company shall assess the credit limit granted to customers for credit purpose. Moreover, as the
     customer base of the Company is large, the credit risk on accounts receivables is not concentrated. In terms of bills receivable
     settlement, external payments are settled with bills receivable with priority and most of the remaining bills are high-quality
     bills with maturity within three months; thus none expected major credit risk exits. In addition, the provision made on the
     impairment of accounts receivables and other receivables are adequate to manage the credit risk.

     Among the accounts receivables of the Company, the accounts receivable of the top five customers accounted for 11.60%
     (31 December 2020: 11.32%); among the other receivables of the Company, the other receivables of the top five customers
     accounted for 60.63% (31 December 2020: 71.95%).




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(4). Liquidity risk

      The Company adopts prudent liquidity risk management for the sufficient supply of monetary funds and liquidity. It secures
      readily available credit loans from banks mainly by maintaining adequate monetary funds and banking facilities. Apart from
      indirect financing from banks, a number of financing channels were available, such as direct financing by inter-bank market
      including short-term financing bills and medium-term financing bills, corporate bonds etc. These instruments can effectively
      reduce the effects of scale of financing and the macro monetary policies of China on indirect bank financing, which shall
      secure adequate funds in a exible manner.

      As at the date of the balance sheet, the contractual cash ows of nancial assets and nancial liabilities are presented below by
      term of maturity:

 ① 31 December 2021


      Item                                Within 1 year        1-2 years           2-5 years    Over 5 years                  Total
      Financial assets:
      Monetary funds                 11,729,230,390.98              0.00                0.00            0.00    11,729,230,390.98
      Financial assets held for
                                        184,638,344.31              0.00                0.00            0.00       184,638,344.31
      trading
      Bills receivables               1,977,286,022.02              0.00                0.00            0.00     1,977,286,022.02
      Accounts receivables            2,853,655,551.54              0.00                0.00            0.00     2,853,655,551.54
      Other receivables                  88,053,825.12              0.00                0.00            0.00        88,053,825.12
      Non-current assets due
                                            317,381.23              0.00                0.00            0.00            317,381.23
      within one year
      Long-term receivables                        0.00      266,904.13                 0.00            0.00            266,904.13
      Subtotal:                      16,833,181,515.20       266,904.13                 0.00            0.00    16,833,448,419.33
      Financial liabilities:
      Short-term borrowings           2,518,484,835.09              0.00                0.00            0.00     2,518,484,835.09
      Financial liabilities held
                                            143,302.24              0.00                0.00            0.00            143,302.24
      for trading
      Bills payables                  1,582,386,767.93              0.00                0.00            0.00     1,582,386,767.93
      Accounts payables                 871,553,210.51              0.00                0.00            0.00       871,553,210.51
      Other payables                  3,292,407,989.79              0.00                0.00            0.00     3,292,407,989.79
      Non-current liabilities
                                         91,576,066.33              0.00                0.00            0.00        91,576,066.33
      due within one year
      Lease liabilities                            0.00   13,186,526.27       11,885,268.05             0.00        25,071,794.32
      Long-term borrowings                         0.00 466,780,252.78       360,000,000.00             0.00       826,780,252.78
      Subtotal:                       8,356,552,171.89 479,966,779.05        371,885,268.05             0.00     9,208,404,218.99




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② 31 December 2020


    Item                               Within 1 year         1-2 years           2-5 years    Over 5 years                  Total
    Financial assets:
    Monetary funds                12,289,098,613.19              0.00                 0.00            0.00    12,289,098,613.19
    Financial assets held for
                                      28,328,748.72              0.00                 0.00            0.00        28,328,748.72
    trading
    Bills receivables              1,343,013,818.54               0.00                0.00            0.00     1,343,013,818.54
    Accounts receivables           2,447,406,222.52               0.00                0.00            0.00     2,447,406,222.52
    Other receivables                177,240,162.81               0.00                0.00            0.00       177,240,162.81
    Non-current assets due
                                      19,934,376.07              0.00                 0.00            0.00        19,934,376.07
    within one year
    Long-term receivables                       0.00       584,284.36                 0.00            0.00           584,284.36
    Subtotal:                     16,305,021,941.85        584,284.36                 0.00            0.00    16,305,606,226.21
    Financial liabilities:
    Short-term borrowings          2,110,942,804.06               0.00                0.00            0.00     2,110,942,804.06
    Financial liabilities held
                                              212.07              0.00                0.00            0.00                212.07
    for trading
    Bills payables                 1,087,759,353.31               0.00                0.00            0.00     1,087,759,353.31
    Accounts payables                832,632,206.53              0.00                 0.00            0.00       832,632,206.53
    Other payables                 2,847,688,065.59              0.00                 0.00            0.00     2,847,688,065.59
    Non-current liabilities
                                        8,539,077.05              0.00                0.00            0.00          8,539,077.05
    due within one year
    Lease liabilities                           0.00     6,266,093.09        3,551,686.95                           9,817,780.04
    Long-term borrowings                        0.00              0.00    360,324,027.48              0.00       360,324,027.48
    Subtotal:                      6,887,561,718.61      6,266,093.09     363,875,714.43              0.00     7,257,703,526.13


2. Capital management
   The capital management policies are made to keep the continuous operation of the Company, to enhance the return to
   shareholders, to benet other stakeholders and to maintain the best capital structure to minimize the cost of capital.

   For the maintenance or adjustment of the capital structure, the Company might adjust financing method, the amount of
   dividends paid to shareholders, return capital to shareholders, issue new shares and other equity instruments or make an asset
   disposal to reduce the liabilities.

   The Company monitors the capital structure with gearing ratio (calculated by dividing total liabilities by total assets). On 31
   December 2021, the Company’s gearing ratio is 35.12% (31 December 2020: 31.68%).




                                                                                                                             257
 3. Transfer of financial assets
(1). Financial assets which are transferred but have not been derecognised in their entirety
     Nil.

(2). Financial assets which have been transferred and ceased to be recognised but still have involvement with the transferor
     On 31 December 2021, the Company's carrying amounts of bank acceptance bills undue and endorsed to suppliers for settling
     account payables is RMB186,290,992.91 (31 December 2020: RMB327,932,359.58); the Company has no commercial
     acceptance bills undue and endorsed to suppliers for settling account payables (31 December 2020: RMB0.00). The Company's
     bank acceptance bill discounted to bank is RMB67,908,033.05 (Last year: RMB208,990,917.90). On 31 December 2021,
     the due dates fall into 1 to 12 months. In accordance with the Law of Negotiable Instruments, the holders of the bills have a
      right of recourse against the Company if payment is refused by the bank of acceptance (the“Continuing Involvement”). In
      the opinion of the Company, the Company has transferred substantially all risks and rewards. Accordingly, their full carrying
      amounts and the associated account payables have been derecognised. The maximum loss and the undiscounted cash flows
      from the Continuing Involvement and repurchasing is equal to their carrying amounts. In the opinion of the Company, the fair
      values of the Continuing Involvement are not signicant.

      During 2021, no gain or loss was generated by the Company on the date of transfer of the bills. The Company had no current
      or accumulated gain or expense arising from the Continuing Involvement in nancial assets which had been derecognised. The
      endorsement was incurred evenly throughout the Period.


IX FAIR VALUE

 1. Closing balance of the fair value of assets and liabilities measured at fair value
      √ Applicable □ N/A
                                                                                                                         Unit: Yuan Currency: RMB
                                                                                                    Closing balance of fair value
                                                                                     Level 1         Level 2            Level 3
       Item
                                                                                   fair value      fair value         fair value             Total
                                                                                measurement     measurement        measurement
       I. Continuous fair value
       measurement
      (Ⅰ)Financial assets held for trading                                 177,262,015.99    7,376,328.32                0.00    184,638,344.31
        1. Financial assets at fair value through prot or loss
      (1)Debt instrument investments                                            940,162.94            0.00                0.00       940,162.94
      (2)Equity instrument investments                                      176,321,853.05            0.00                0.00    176,321,853.05
      (3)Derivative nancial assets                                                    0.00    7,376,328.32                0.00      7,376,328.32
        2. Financial asset designated as at fair value through prot or loss
      (1)Investments in debt instruments
      (2)Investments in equity instruments
       (II) Other debt investments
       (III) Other investments in equity instruments                          212,384,666.97            0.00     196,497,710.45 1,408,882,377.42
       (IV) Investment properties
       1. A land use right that is used to be leased out.
       2. A building that is leased out.
       3. A land use right held for transfer upon capital appreciation
       (V) Biological asset
       1. Consumable biological assets
       2. Productive biological assets
       Total assets continuously measured at fair value                       389,646,682.96    7,376,328.32 1,196,497,710.45 1,593,520,721.73




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                                                                                                   Closing balance of fair value
                                                                                    Level 1         Level 2            Level 3
    Item
                                                                                  fair value      fair value         fair value          Total
                                                                               measurement     measurement        measurement
    (VI) Held-for-trading nancial liabilities
    1. Financial liabilities at fair value through prot or loss                        0.00      143,302.24                0.00     143,302.24
    Of which: Issued tradable bonds
    Derivative nancial liabilities                                                     0.00      143,302.24                0.00     143,302.24
    Others
    2. Financial liabilities designated as at fair value through prot or
    loss
    Total liabilities measured at fair value on a recurring basis                      0.00      143,302.24                0.00     143,302.24
    II. Non-recurring fair value measurement
    ( Ⅰ )Held-for-sale assets                                                         0.00            0.00                0.00           0.00
    Total assets measured at fair value on a non-recurring basis                       0.00            0.00                0.00           0.00
    Total liabilities measured at fair value on a non-recurring basis                  0.00            0.00                0.00           0.00


   In 2021, there were no transfers of the fair value measurements between level 1 and level 2 and no transfers into or out of level
   3.


2. Basis for determining the market price of continuous and non-continuous level 1 fair value
   measurement items
   √ Applicable □ N/A

   The basis for determining the market price of level 1 fair value measurement items is when listed and traded on the Shanghai
   Stock Exchange, Shenzhen Stock Exchange, Hong Kong Stock Exchange and the United States, its fair value is determined by
   the closing price on the last trading day of the reporting period.


3. Valuation techniques and qualitative and quantitative information of key parameters adopted for continuous and non-
   continuous level 2 fair value measurement items
   √ Applicable □ N/A

   Valuation techniques and quantitative and quantitative information of key parameters adopted for level 2 fair value
   measurement items (1) The derivative financial instruments are foreign exchange forward contracts, and the fair value is
   calculated and determined based on the corresponding forward exchange rate of the expiring contract. (2) The fair value
   of some other equity instruments held is determined by the equity value recorded in the equity notice provided by the
   counterparty at the end of the year.


                                             Fair value at the End
    Item                                                                                          Valuation techniques
                                                     of the Period
                                                                           The fair value is measured at the forward exchange rate quoted by
    Derivative nancial assets                         7,376,328.32
                                                                           the respective matured contract
                                                                           The fair value is measured at the forward exchange rate quoted by
    Derivative nancial liabilities                      143,302.24
                                                                           the respective matured contract




                                                                                                                                          259
 4. Valuation techniques and qualitative and quantitative information of key parameters adopted for continuous and non-
    continuous level 3 fair value measurement items
      √ Applicable □ N/A

      The fair value of some other equity instruments held is the best estimate based on the cost or the present value of expected
      future net cash ows.


 5. Reconciliation between opening and closing carrying amounts and sensitivity analysis of
      unobservable parameters for continuous level 3 fair value measurement items
      √ Applicable □ N/A


                                                                                          Fair value at the
      Item                                                                                                  Valuation techniques
                                                                                         End of the Period
      Other equity instrument investments- Shanghai Yunfeng Xinchuang Equity
                                                                                            94,040,236.88 Net asset method
      Investment Center
      Other equity instrument investments - Shanghai JingYi Investment Center (L.P.)        66,175,062.50 Net asset method
      Other equity instrument investments-Qianhai Equity Investment Fund(L.P.)             264,930,500.00 Net asset method
      Other equity instrument investments –Apricot Forest, Inc                            137,711,800.01 Income approach
      Other equity instrument investments – China Resources Bank of Zhuhai Co., Ltd.      164,395,200.00 Market method
      Other equity instrument investments -PANTHEOND,L.P.                                    3,715,566.69 Net asset method
      Other equity instrument investments –GLOBAL HEALTH SCIENCE                          235,133,216.46 Net asset method
      Other equity instrument investments –SCC VENTURE VI 2018-B,L.P.                       6,615,626.07 Net asset method
      Other equity instrument investments –Nextech V Oncology S.C.S., SICAV-SIF            30,667,263.04 Net asset method
      Other equity instrument investments - Yizun Biopharmaceutics (Shanghai) Co.,
                                                                                            59,999,953.41 latest nancing price
      Ltd.
      Other equity instrument investments - Zhuhai Medpha Biotechnology Co., Ltd.            6,971,000.00 latest nancing price
      Other equity instrument investments- Beijing Luzhu Biotechnology Co., Ltd.            41,944,015.67 latest nancing price
      Other equity instrument investments -Others                                           84,198,269.72 Cost method
      Total                                                                              1,196,497,710.45


 6. In case of transfers among levels for the current period, explain the transfer reasons and policies for determining
    transfer time point for continuous fair value measurement items
      □ Applicable √ N/A


 7. Changes in valuation techniques for the current period and reasons for changes
      □ Applicable √ N/A


 8. Fair value of financial assets and liabilities not measured at fair value
      □ Applicable √ N/A


 9. Others
      □ Applicable √ N/A




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X RELATED PARTIES AND RELATED TRANSACTIONS

1. Parent company of the Company
    √ Applicable □ N/A
                                                                                                                     Unit: Yuan Currency: RMB
                                                                                              Percentage of the            Percentage of the
     Name of
                    Place of                                              Registered       entity's shareholding        entity's voting rights
     parent                        Nature of business
                    registration                                             capital         held by the parent           held by the parent
     company
                                                                                                   company (%)                  company (%)
     Shenzhen                      investment and establishment
     Baiyeyuan                     of industry, domestic
                    Shenzhen                                          80,000,000.00                          46.95                     46.95
     Investment                    commerce, and material
     Co., Ltd.                     supply and marketing


    Notes to the parent company of the Company:

    The parent company of the Company is Shenzhen Baiyeyuan Investment Co., Ltd., which was established on 21 January
    1999, and its main business scope is investment and establishment of industry, domestic commerce, and material supply and
    marketing.

    The ultimate controller of the Company: Zhu Baoguo

    Other descriptions:

(1) Parent company's registered capital and its changes


                                                        Balance at the Beginning       Increase for     Decrease for      Balance at the End
     Name of parent company
                                                                    of the Period        the Period       the Period           of the Period
     Shenzhen Baiyeyuan Investment Co., Ltd.                        80,000,000.00             0.00               0.00         80,000,000.00


(2) Shares of the company held by the parent company and their changes


                                       Balance at the                                                          Balance at the
                                                                          Increase for     Decrease for
     Name of parent company             Beginning of       Proportion                                                 End of      Proportion
                                                                            the Period       the Period
                                          the Period                                                              the Period
     Shenzhen Baiyeyuan
                                      895,653,653.00           45.87%               0.00              0.00    895,653,653.00         46.95%
     Investment Co., Ltd.


2. The Company's subsidiaries
    For details of the subsidiaries of the Company, please refer to notes Ⅶ .1.
    √ Applicable □ N/A

    Please refer to notes Ⅶ .1. for the details of subsidiaries.




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 3. Joint ventures and associates of the Company
      For details of the signicant joint ventures or associates of the Company, please see the notes.
      √ Applicable □ N/A

      Please refer to notes Ⅶ .2. for the details of the joint ventures and associates.
      Other joint ventures or associates entered into transactions with the Company during the Period, or during the prior period with
      remaining closing balance were as follows:
      √ Applicable □ N/A


      Name of joint ventures and associates                                                   Relationship with the Company
      Jiaozuo Jinguan Jiahua Electric Power Co., Ltd.                                         Associate
      Guangdong Blue Treasure Pharmaceutical Co., Ltd.                                        Associate
      Novastage Pharmaceuticals (Shenzhen), Ltd.                                              Associate
      Shenzhen City Youbao Technology Co., Ltd.                                               Associate
      AbCyte Therapeutics Inc.                                                                Associate
      L&L Biopharma, Co. Ltd.                                                                 Associate
      Zhuhai Sanmed Biotech Inc.                                                              Associate
      Aetio Biotherapy Inc                                                                    Associate
      Jiangsu Atom Bioscience and Pharmaceutical Co., Ltd.                                    Associate
      Tianjin Tongrentang Group Co., Ltd.                                                     Associate
      Innite Intelligence Pharma                                                              Associate
      Zhuhai Sanmed Gene Diagnostics Ltd.                                                     A company controlled by the associate
      Zhuhai Hengqin Weisheng Precision Medicine Technology Co., Ltd.                         A company controlled by the associate


      Other descriptions
      □ Applicable √ N/A


 4. Other related parties of the Company
      √ Applicable □ N/A


      Name of other related parties                                                            Relationship with the Company
      Shenzhen Taitelixing Investment Development Co., Ltd.                                    Others
      Zhuozhou Jingnan Yongle Golf Club Co., Ltd.                                              Others
      Shenzhen Health Deer Technology Co., Ltd.                                                Others
      Sichuan Healthy Deer Hospital Management Co., Ltd. and its subsidiaries                  Others
      Zhuhai Medpha Biotechnology Co., Ltd.                                                    Others
      Zhuhai Xianghetai Investment Management Partnership (Limited Partnership)                Others
      Zhuhai Zhong Hui Yuan Investment Partnership (Limited Partnership)                       Others
      Zhuhai Liying Investment Management Partnership (Limited Partnership)                    Others
      Jiangsu One Winner Medical Technology Co., Ltd.                                          Others
      Directors, Supervisors and other senior management personnel                             Others




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5. Related transactions
(1). Sales and purchase of goods, rendering and receipt of services
     Purchase of goods, receipt of services
     √ Applicable □ N/A
                                                                                                            Unit: Yuan Currency: RMB
                                                              Description of related         Amount for the          Amount for the
     Related party
                                                              party transaction                     Period           Previous Period
     Guangdong Blue Treasure Pharmaceutical Co., Ltd.         Raw materials                    2,786,053.10            3,938,902.64
     Zhuhai Sanmed Biotech Inc.                               Finished goods                      28,558.55              184,070.79
     Zhuhai Medpha Biotechnology Co., Ltd.                    Raw materials                             0.00               27,079.65
     Sichuan Healthy Deer Hospital Management Co., Ltd. Finished goods,
                                                                                                 887,872.67                     0.00
     and its subsidiaries                               Business promotion
                                                              Finished goods,
     Jiangsu One Winner Medical Technology Co., Ltd.                                             408,427.00                     0.00
                                                              Business promotion
     Zhuhai Sanmed Gene Diagnostics Ltd.                      Testing                             14,377.36                52,415.09
     L&L Biopharma, Co. Ltd.                                  R&D                                943,396.20                     0.00
     Shenzhen City Youbao Technology Co., Ltd.                Business promotion               1,062,850.00                     0.00
     Zhuozhou Jingnan Yongle Golf Club Co., Ltd.              Membership service                  84,037.00                     0.00
     Innite Intelligence Pharma                               R&D                                148,514.85                     0.00
     Jiaozuo Jinguan Jiahua Electric Power Co., Ltd.          Electricity, steam             212,585,953.81          157,947,440.20


    Sales of goods, provision of services
    √ Applicable □ N/A
                                                                                                            Unit: Yuan Currency: RMB
                                                              Description of related         Amount for the          Amount for the
     Related party
                                                              party transaction                     Period           Previous Period
     Guangdong Blue Treasure Pharmaceutical Co., Ltd.         Finished goods                  63,972,886.45           41,584,936.24
                                                              Macromolecule
     Zhuhai Medpha Biotechnology Co., Ltd.                                                              0.00             209,736.83
                                                              materials
     Zhuhai Sanmed Gene Diagnostics Ltd.                      Finished goods                     577,453.14              428,384.87
     Sichuan Healthy Deer Hospital Management Co., Ltd.
                                                        Finished goods                         4,951,551.99                     0.00
     and its subsidiaries
                                                              Water, electricity,
     Zhuhai Sanmed Biotech Inc.                                                                  667,998.89            1,337,996.41
                                                              power and others


    Descriptions of related party transactions with respect to the sales and purchase of goods, rendering and receipt of services
    □ Applicable √ N/A

(2). Related entrusted management/contracting and entrusting management/outsourcing
     Table of the entrusted management/contracting of the Company:
     □ Applicable √ N/A

    Descriptions of related trusteeship/outsourcing
    □ Applicable √ N/A

    Table of the entrusting management/outsourcing of the Company:
    □ Applicable √ N/A

    Descriptions of related management/outsourcing
    □ Applicable √ N/A



                                                                                                                                    263
(3). Related party leases
     The Company as a lessor
     √ Applicable □ N/A
                                                                                                          Unit: Yuan Currency: RMB
                                                                                            Lease income            Lease income
                                                                  Type of leased
      Name of lessee                                                                    recognised for the      recognised for the
                                                                  assets
                                                                                                   Period         Previous Period
      Zhuhai Sanmed Biotech Inc.                                  Buildings                    2,226,299.00          3,067,097.00
      Zhuhai Sanmed Gene Diagnostics Ltd.                         Buildings                     240,000.00             140,000.00
      Shenzhen Baiyeyuan Investment Co., Ltd.                     Buildings                      18,891.76              18,891.76
                                                                  Buildings &
      Novastage Pharmaceuticals (Shenzhen), Ltd.                                                315,457.80              81,594.55
                                                                  Equipment
      Shenzhen Taitelixing Investment Development Co., Ltd.       Buildings                      18,720.00              18,720.00
      Shenzhen Healthy Deer Information Technology Co., Ltd.      Buildings                      17,174.32              17,174.32
      Shenzhen City Youbao Technology Co., Ltd.                   Buildings                      17,174.32              17,174.32


      The Company as a lessee:
      □ Applicable √ N/A

      Descriptions of related leases
      □ Applicable √ N/A

(4). Related party guarantees
     The Company as the guarantor
     √ Applicable □ N/A
                                                                                                    Unit: 10,000 Yuan Currency: RMB
                                                                                                                  Performance
      Name of guaranteed party         Guarantee amount    Actual date of event    Guarantee maturity date
                                                                                                                completed or not
      Jinguan Electric Power                    4,800.00   2021/2/23               2022/2/23                           No
      Jinguan Electric Power                   10,000.00   2021/3/3                2022/2/25                           No
      Jinguan Electric Power                    4,000.00   2021/7/8                2022/7/8                            No
      Jinguan Electric Power                    5,000.00   2021/7/14               2022/7/14                           No
      Jinguan Electric Power                    3,000.00   2021/7/16               2022/6/16                           No
      Jinguan Electric Power                    3,000.00   2021/8/12               2022/8/12                           No
      Jinguan Electric Power                    3,200.00   2021/9/23               2022/9/22                           No
      Jinguan Electric Power                    3,200.00   2021/10/11              2022/10/11                          No
      Jinguan Electric Power                    3,800.00   2021/10/13              2022/10/12                          No
      Sanmed Biotech                            2,900.00   2021/1/1                2021/5/6                           Yes


      The Company as the guaranteed party
      □ Applicable √ N/A

      Descriptions of guarantees with related parties
      √ Applicable □ N/A

 ① In order to ensure the stable development of production and operation of Jinguan Electric Power, the Company and its
    controlling subsidiary Jiaozuo Joincare jointly provided a revolving guarantee line with balance of no more than RMB350
    million (inclusive) for Jinguan Electric Power (specific guarantors shall be specified in the guarantee contracts) according
    to“the Resolution on Providing Loan Guarantee for Jinguan Electric Power by the Company and Its Controlling Subsidiary
    Jiaozuo Joincare”considered and approved at the First Extraordinary General Meeting of the Company on 6 July 2016, with
    the guarantee period starting from the date when the resolution was considered and approved to 31 December 2019. Pursuant



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                                                                                                                          2021


    to“the Resolution on Providing Loan Guarantee for Jinguan Electric Power by the Company and Its Controlling Subsidiary
    Jiaozuo Joincare”considered and approved at the 2017 Annual General Meeting of the Company on 22 May 2018, the
    Company and its controlling subsidiary Jiaozuo Joincare jointly provided a revolving guarantee line with balance of no more
    than RMB350 million (inclusive) for Jinguan Electric Power (specic guarantors shall be specied in the guarantee contracts),
    with the guarantee period starting from the date when the resolution was considered and approved to 31 December 2022. In
    order to ensure the stable development of production and operation of Jinguan Electric Power, the revolving guarantee line
    with balance of no more than RMB350 million (inclusive) for Jinguan Electric Power (specic guarantors shall be specied in
    the guarantee contracts) considered and approved at the 2017 General Meeting of the Company was changed to the revolving
    guarantee line with balance of no more than RMB450 million (inclusive) on 16 April 2019 due to the actual business needs of
    Jinguan Electric Power, with the guarantee period starting from the date when the resolution was considered and approved to
    31 December 2022.

    As at 31 December 2021, the Company provided Jinguan Electric Power with guarantees for loans of RMB400 milliom;
    RMB100 million in Shenzhen Branch of China Zheshang Bank, RMB80 million in Shenzhen Branch of Nanyang Commercial
    Bank, and RMB220 million in Shenzhen Branch of China Everbright Bank.

    In order to ensure the safety of secured loans, Jinguan Electric Power provided counter guarantees for the said guarantees
    provided by the Company based on its owned assets, and undertook that it would unconditionally provide mutual guarantees
    for the Company or its controlling subsidiary designated with total line of no more than RMB450 million (inclusive) whenever
    the Company deemed necessary.

② The Company has provided a“Letter of Undertaking for Counter Guarantee”, pursuant to which it has undertaken to provide
   a joint liability guarantee for 33.07% of the obligation of Livzon Group under the guarantee provided to Livzon MABPharm
   Inc. * ( 珠海市丽珠单抗生物技术有限公司 ), and the guarantee period of which will be expired on the expiry date of Livzon
   Group's obligation thereunder.

③ Zhuhai Liying Investment Management Partnership (Limited Partnership) ( 珠 海 丽 英 投 资 管 理 合 伙 企 业 ( 有 限 合 伙 )), the
   other shareholder of Livzon Diagnostics, has provided a“Letter of Undertaking for Counter Guarantee”, pursuant to which
   it has undertaken to provide a joint liability guarantee for 9.025% of the obligation of Livzon Group under the guarantee
   provided to Livzon Diagnostics, and the guarantee period of which will be expired on the expiry date of Livzon Group's
   obligation thereunder.

④ Zhuhai Zhong Hui Yuan Investment Partnership (Limited Partnership) ( 珠 海 中 汇 源 投 资 合 伙 企 业( 有 限 合 伙 )), the
   other shareholder of Livzon Group Xinbeijiang Pharmaceutical Manufacturing Inc. ( 丽 珠 集 团 新 北 江 制 药 股 份 有 限 公
   司 ), has provided a“Letter of Undertaking for Counter Guarantee”, pursuant to which it has undertaken to provide a joint
   liability guarantee for 8.44% of the obligation of Livzon Group under the guarantee provided to Livzon Group Xinbeijiang
   Pharmaceutical Manufacturing Inc.( 丽珠集团新北江制药股份有限公司 ) and the guarantee period of which will be expired
   on the expiry date of Livzon Group's obligation thereunder.

⑤ Other shareholders of Zhuhai Sanmed Biotech Inc. ( 珠 海 圣 美 生 物 诊 断 技 术 有 限 公 司 ) including Li Lin and Shi Jianfeng
   have provided“Letter of Undertaking for Counter Guarantee”, pursuant to which they have undertaken to provide a joint
   liability guarantee for a total of 74.0822% of the obligation of Livzon Group under the guarantee provided to Zhuhai Sanmed
   Biotech Inc. ( 珠 海 圣 美 生 物 诊 断 技 术 有 限 公 司 ) and the guarantee period of which will be expired on the expiry date of
   Livzon Group's obligation under the guarantee.

⑥ On 24 December 2020, Livzon Group signed a guarantee agreement with Zhuhai Branch of Industrial and Commercial Bank
   of China Limited * ( 中 国 工 商 银 行 股 份 有 限 公 司 珠 海 分 行 ) in the amount of RMB29 million to secure the credit facility
   granted to Zhuhai Sanmed Biotech Inc. ( 珠海圣美生物诊断技术有限公司 ) by Zhuhai Branch of Industrial and Commercial
   Bank of China Limited * ( 中国工商银行股份有限公司珠海分行 ) and the guarantee period of which will be expired on 24
   December 2021. During the Period, Livzon Group provided guarantee to Zhuhai Sanmed Biotech Inc. ( 珠海圣美生物诊断技
   术 有 限 公 司 ) at an actual amount of RMB29 million. As at 31 December 2021, the total balance of actual amount guaranteed
   by Livzon Group to Zhuhai Sanmed Biotech Inc. ( 珠海圣美生物诊断技术有限公司 ) was nil.




                                                                                                                                 265
(5). Lending funds of related parties
     □ Applicable √ N/A

(6). Asset transfer and debt restructuring between related parties
     √ Applicable □ N/A
                                                                                                                  Unit: Yuan Currency: RMB
                                                                                                      Amount for the      Amount for the
      Related party                                 Description of related party transaction
                                                                                                       current period       prior period
      L&L Biopharma, Co., Ltd.
                                                    Acquisition of technical know-how                           0.00        3,773,584.80
      ( 上海健信生物医药科技有限公司 )
      Zhuhai Sanmed Biotech Inc.                    Transfer of equity interest in Zhuhai
                                                                                                                0.00       20,000,000.00
      ( 珠海圣美生物诊断技术有限公司 )              Sanmed Gene Diagnostics Ltd.
      Zhuhai Hengqin Weisheng Precision
      Medicine Technology Co., Ltd.                 Sales of equipment                                     17,699.12                0.00
      ( 珠海横琴维胜精准医学科技有限公司 )


(7). Remuneration of key management personnel
     √ Applicable □ N/A
                                                                                                           Unit: 10,000 Yuan Currency: RMB
      Item                                                       Amount for the current period                Amount for the prior period
      Remuneration of key management personnel                                        1734.05                                    1,719.66


      Remuneration of key management personnel is disclosed as follows:
      2021
                                                                                                           Unit: 10,000 Yuan Currency: RMB
                                           Fees of     Salaries            Housing                Compensation
                                                                   Social
                                         Director/         and            provident         Bonus    for loss of        Others      Total
                                                                insurance
                                        Supervisor allowances                  fund                       oce
      Directors:
      Zhu Baoguo
                                           330.94         0.00         6.22       2.40         0.00              0.00     0.00    339.56
      ( 朱保国 )
      Liu Guangxia ( 刘广霞 )              330.94       17.91          8.01       2.40         0.00              0.00     0.00    359.27
      Yu Xiong ( 俞雄 )                      0.00      240.00          0.00       0.00       95.00               0.00     0.00    335.00
      Qiu Qingfeng ( 邱庆丰 )                0.00      135.00          6.22       2.40       30.00               0.00     0.00    173.62
      Lin Nanqi ( 林楠棋 )                   0.00      135.00          6.22       2.40       30.00               0.00     0.00    173.62
      Cui Liguo ( 崔利国 )                  10.00         0.00         0.00       0.00         0.00              0.00     0.00     10.00
      Huo Jing ( 霍静 )                     10.00         0.00         0.00       0.00         0.00              0.00     0.00     10.00
      Qin Yezhi ( 覃业志 )                  10.00         0.00         0.00       0.00         0.00              0.00     0.00     10.00
      Peng Juan(彭娟)                      3.60         0.00         0.00       0.00         0.00              0.00     0.00      3.60
      Supervisors:
      Yu Xiaoyun ( 余孝云 )                  4.00       38.16          6.01       2.18       17.95               0.00     0.00     68.29
      Peng Jinhua ( 彭金花 )                 4.00       32.73          0.00       1.36         0.00              0.00     0.00     38.09
      Xie Youguo(谢友国)                   4.00       36.35          0.00       1.17         2.86              0.00     0.00     44.38
      Other senior management:
      Zhao Fenguang ( 赵凤光 )               0.00      135.00          6.22       2.40       25.00               0.00     0.00    168.62
      Total                                707.48      770.14         38.88      16.74      200.81               0.00     0.00 1,734.05


      Note: Mr. Zhu Baoguo serves as the chairman of Livzon, a controlled subsidiary of the Company; and Mr. Yu Xiong and Mr.
      Qiu Qingfeng serve as non-executive directors of Livzon. The remuneration listed above does not include the part paid by
      Livzon. Please refer to Livzon's 2021 Annual Report for details.


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    2020
                                                                                                    Unit: 10,000 Yuan Currency: RMB
                                       Fees of     Salaries            Housing               Compensation
                                                               Social
                                    Director/         and            provident        Bonus    for loss of      Others       Total
                                                            insurance
                                    Supervisor allowances                  fund                      oce
     Directors:
     Zhu Baoguo
                                        312.52         0.00        4.33        2.16      0.00             0.00      0.00    319.01
     ( 朱保国 )
     Liu Guangxia ( 刘广霞 )            312.52         0.00        4.35        2.16      0.00             0.00      0.00    319.03
     Qiu Qingfeng ( 邱庆丰 )              0.00       260.09        4.35        2.16      0.00             0.00      0.00    266.60
     Lin Nanqi ( 林楠棋 )                 0.00        82.04        4.35        2.16     68.32             0.00      0.00    156.87
     Cui Liguo ( 崔利国 )                 9.60         0.00        0.00        0.00      0.00             0.00      0.00      9.60
     Huo Jing ( 霍静 )                    9.60         0.00        0.00        0.00      0.00             0.00      0.00      9.60
     Qin Yezhi ( 覃业志 )                 5.60         0.00        0.00        0.00      0.00             0.00      0.00      5.60
     Hu Qin ( 胡庆 )(Resigned )         4.00         0.00        0.00        0.00      0.00             0.00      0.00      4.00
     Supervisors:
     Yu Xiaoyun ( 余孝云 )                3.60        26.01        3.81        1.51     16.93             0.00      0.00     51.87
     Peng Jinhua ( 彭金花 )               3.60        60.09        0.00        2.16     34.83             0.00      0.00    100.67
     Xie Youguo 谢友国                    3.60        36.82        0.00        2.01      2.86             0.00      0.00     45.29
     Other senior management:
     Yu Xiong ( 俞雄 )                    0.00       109.37        0.00        0.00     70.30             0.00      0.00    179.67
     Zhao Fengguang ( 赵凤光 )            0.00        91.22        4.35        2.16     61.98             0.00      0.00    159.71
    Tang Lingzhi ( 汤凌志 )
                                          0.00        60.81        4.35        2.16     24.83             0.00      0.00     92.14
    (Resigned)
     Total                              664.65       726.45       29.90       18.61    280.05             0.00      0.00 1,719.66


    Note: Mr. Zhu Baoguo serves as the chairman of Livzon, a controlled subsidiary of the Company; and Mr. Yu Xiong and Mr.
    Qiu Qingfeng serve as non-executive directors of Livzon. The remuneration listed above does not include the part paid by
    Livzon. Please refer to Livzon's 2020 Annual Report for details.

(8). Other related transactions
     √ Applicable □ N/A

    The Company, Livzon Group (a subsidiary of the Company), International Limited (“Livzon International”, a wholly-owned
    subsidiary of the Company), Joincare Pharmaceutical Group Industry Co., Ltd. (“Joincare BVI”, a wholly-owned subsidiary
    of the Compang), YF Pharmab Limited (“YF”) and Livzon Biologics Limited (“Livzon Cayman”, a controlling company
    of the Livzon Group), as well as its controlled entities, including Livzon Biologics Hong Kong Limited ( 丽 珠 生 物 科 技 香 港
    有限公司 ), (“Livzon HK”), Zhuhai Livzon Biotechnology Co., Ltd. ( 珠海市丽珠生物医药科技有限公司 )(“LivzonBio”),
    Livzon MABPharm Inc. ( 珠 海 市 麗 珠 單 抗 生 物 技 術 有 限 公 司 ) (“Livzon MAB”), Zhuhai Kadi Medical Biotechnology
    Inc. ( 珠 海 市 卡 迪 生 物 医 药 有 限 公 司 ) (“Kadi”) (collectively known as the“Subsidiaries under Livzon Cayman”) have
    jointly entered into the reorganization framework agreement (the“Reorganization Framework Agreement”), pursuant to
    which the parties have agreed to implement the proposed reorganization of shareholding structures of the Subsidiaries under
    Livzon Cayman, so that LivzonBio will become the controlling company of the domestic and overseas Subsidiaries under
    Livzon Cayman. On 8 January 2021, the Resolution on the Connected Transactions in relation to the Reorganization of the
    Shareholding Structures of the Controlling Subsidiaries of the Company was passed at the 2021 first extraordinary general
    meeting of the Livzon Group, at which the above transaction was considered and approved. Details of the transaction were set
    out as below:

    A. The equity transfer and capital increase of LivzonBio: the Livzon Group and the Company agreed to acquire 51% and 49%
    equity interest in LivzonBio from Livzon HK at a consideration of RMB24,316,290 and RMB23,362,710, respectively.




                                                                                                                               267
      Meanwhile, the registered capital of LivzonBio was increased from RMB250 million to RMB600 million with pro rata
      registered capital subscription from the Livzon and the Company on the basis of RMB1 of the registered capital for RMB1 of
      the subscription, of which Livzon Group contributed RMB281,722,419.00 and the Company contributed RMB270,674,481.00,
      respectively.

      B. Transfer to the domestic market from the overseas through Series A Financing:Livzon Group and YF made investment in
      LivzonBio, pursuant to which Livzon Group and YF subscribed for the increased registered capital of RMB147,401,875 and
      RMB74,954,742 of LivzonBio at a consideration of US$98,299,320 (equivalent to RMB637,421,940.54) and US$50,000,000
      (equivalent to RMB324,225,000.00), respectively.

      C. Equity transfer of Livzon Mab: LivzonBio acquired the 100% equity interest of Livzon MAB from Livzon HK at a
      consideration of RMB1.48 billion.

      D. Equity transfer and capital reduction of Livzon HK: LivzonBio acquired the 100% equity interest of Livzon HK from
      Livzon Cayman at a consideration of US$6.10 million (equivalent to RMB39,445,700). Livzon HK returned capital to Livzon
      Cayman, so that Livzon Cayman recovered part of the investment amount in Livzon HK, which is equivalent to the total
      capital reduction paid to Livzon International, Joincare BVI and YF upon capital reduction of Livzon Cayman.

      E. Streamline the overseas shareholding structure: Each of Livzon International, YF and Joincare BVI issued a Repurchase
      Letter to Livzon Cayman, pursuant to which Livzon Cayman repurchased its shares held by them. As at 13 May 2021, Livzon
      Cayman had repurchased an aggregate of 137,074,829 issued shares and had fully settled the corresponding consideration. The
      above share repurchases have been completed and Livzon Cayman only preserves 1 issued ordinary share, which will be held
      by Livzon International, and Livzon Cayman has become a wholly-owned subsidiary of Livzon International.


 6. Amounts due from/to related parties
(1). Amounts due from related parties
     √ Applicable □ N/A
                                                                                                                         Unit: Yuan Currency: RMB
                                                                                Balance at the End of the Period Balance at the Beginning of the Period
      Item                 Related parties                                                        Provision for                           Provision for
                                                                                Book balance                         Book balance
                                                                                                     bad debts                               bad debts
      Bills receivables    Guangdong Blue Treasure Pharmaceutical Co. Ltd.       5,492,960.00             0.00                0.00                0.00
      Accounts receivables Guangdong Blue Treasure Pharmaceutical Co. Ltd.      18,889,500.00       490,875.00        5,092,960.00           52,457.49
      Accounts receivables Zhuhai Sanmed Gene Diagnostics Inc.                    224,023.83          8,578.07           38,563.14              374.06
                           Sichuan Healthy Deer Hospital Management Co., Ltd.
      Accounts receivables                                                        337,395.02         48,933.97                0.00                0.00
                           and its subisidaries
                           Sichuan Healthy Deer Hospital Management Co., Ltd.
      Prepayments                                                                        0.00             0.00          153,900.00                0.00
                           and its subisidaries
      Prepayments          Zhuhai Sanmed Biotech Inc.                             211,200.00              0.00          211,200.00                0.00
      Prepayments          Shenzhen City Youbao Technology Co., Ltd               154,500.00              0.00                0.00                0.00
      Prepayments          Jiaozuo Jinguan Jiahua Electric Power Co., Ltd.       8,240,517.56             0.00                0.00                0.00
      Other receivables    Zhongshan Renhe Health Products Co., Ltd.              469,895.78        469,895.78          469,895.78          469,895.78
      Other receivables    Shenzhen Jiekang Health Care Co., Ltd.               18,577,246.63    18,577,246.63       18,577,246.63       18,577,246.63
      Other receivables    Shenzhen Health Deer Technology Co., Ltd.                 4,680.00            74.38                0.00                0.00
      Other receivables    Guangdong Blue Treasure Pharmaceutical Co. Ltd.       1,271,496.55        21,233.99                0.00                0.00
      Other receivables    Zhuhai Sanmed Biotech Inc.                                    0.00             0.00       15,000,000.00          415,461.96
      Other receivables    Zhuhai Sanmed Gene Diagnostics Inc.                       5,265.00            87.93           10,530.00              291.65
      Non-current assets   Zhuhai Zhong Hui Yuan Investment Partnership
                                                                                         0.00             0.00       10,967,767.26                0.00
      due within one year: (Limited Partnership)
      Other non-current
                           L&L Biopharma, Co. Ltd.                                       0.00             0.00        1,740,994.29                0.00
      assets:



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                                                                                                                        2021



(2). Amount due to related parties
     √ Applicable □ N/A
                                                                                                         Unit: Yuan Currency: RMB
                                                                                   Balance at the End    Balance at the Beginning
     Item                Related parties
                                                                                        of the Period                of the Period
     Bills payables      Guangdong Blue Treasure Pharmaceutical Co. Ltd.                  379,960.00                         0.00
     Accounts
                         Jiaozuo Jinguan Jiahua Electric Power Co., Ltd.                        0.00               31,681,080.57
     payables
     Dividends           Zhuhai Zhong Hui Yuan Investment Partnership
                                                                                                0.00                 1,466,606.04
     payable             (Limited Partnership)
                         Sichuan Healthy Deer Hospital Management Co., Ltd.
     Other payables                                                                         8,936.17                         0.00
                         and its subisidaries


XI SHARE-BASED PAYMENT

1. General information about share-based payment
    √ Applicable □ N/A
                                                                                                        Unit: Share Currency: RMB
     Total equity instruments granted during the Current Period by the Company                                                  0
     Total equity instruments exercised during the Current Period by the Company                                      10,082,440
     Total equity instruments of the Company expired during the Current Period                                                  0
     Range of exercise price of share option of the Company outstanding and remaining
                                                                                                                             Note
     term of contract as at the End of the Period
     Range of exercise price of other equity instruments of the Company and remaining
                                                                                                                                 -
     term of contract as at the End of the Period


    Note: Share Option

① On 13 December 2018,“the Resolution on 2018 Share Options Incentive Scheme (Draft) and its summary”,“the Resolution
   on Administrative Measures for Appraisal System of the 2018 Share Options Incentive Scheme of Livzon Pharmaceutical
   Group Inc.”and“the Resolution on the General Meeting for Granting Mandate to the Board to Deal with Matters Regarding
    the 2018 Share Options Incentive Scheme”were considered and approved at the 2018 Third Extraordinary General Meeting.
    On 21 December         “the Resolution in Relation to the Adjustment of the Quantity to be Granted and the List of Incentive
    Participants of the Grant under 2018 Share Options Incentive Scheme”and“the Resolution on the First Grant of Share
    Options to Incentive Participants”were considered and approved at the 6th Meeting of the 7th Session of the Board and the 5th
    Meeting of the 7th Session of the Supervisory Committee. On 24 January 2019,“the Resolution in Relation to the Adjustment
    of the Quantity to be Granted and the List of Incentive Participants of the Grant under 2018 Share Options Incentive Scheme”
    was considered and approved at the 7th Meeting of the 7th Session of the Board and the 6th Meeting of the 7th Session of
    the Supervisory Committee, pursuant to which,21 December 2018 was set as the date of grant, on which 35.72 million share
    options were granted to 320 incentive participants at an exercise price of RMB8.21 per share option.

    Pursuant to“the Resolution relating to Cancellation of Certain Share Options of the Company Granted but Not Yet Exercised
    under the 2018 Share Option Incentive Plan”considered and approved at the 12th Meeting of the 7th Session of the Board
    of the Company on 10 June 2019, 3.95 million share options that have been granted but not yet exercised by 39 Incentive
    Participants who resigned due to personal reasons and did not meet the incentive conditions are canceled. After the completion
    of the cancellation, the number of Incentive Participants for the first grant of the 2018 share options incentive scheme of the
    Company was adjusted from 320 to 281, while the number of share options under the first grant was adjusted from 35.72




                                                                                                                              269
      million to 31.77 million.

      Pursuant to“the Resolution relating to Cancellation of Certain Share Options of the Company Granted but Not Yet Exercised
      under the 2018 Share Option Incentive Plan”considered and approved at the 17th Meeting of the 7th Session of the Board
      of the Company on 28 October 2019, 2.46 million share options that have been granted but not yet exercised by 23 Incentive
      Participants who resigned due to personal reasons and did not meet the incentive conditions are canceled. After the completion
      of the cancellation, the number of Incentive Participants for the first grant of the 2018 share options incentive scheme of the
      Company was adjusted from 281 to 258, while the number of share options under the first grant was adjusted from 31.77
      million to 29.31 million.

      Pursuant to“the Resolution on Fulfillment of Exercise Conditions for the First Exercise Period of the First Grant under the
      2018 Share Options Incentive Scheme”considered and approved at the 19th Meeting of the 7th Session of the Board of the
      Company on 4 December 2019, it was believed that the exercise conditions for the rst exercise period of the rst grant under
      the Incentive Scheme had been achieved, and it was agreed that the 258 incentive participants who had fulfilled the exercise
      conditions might exercise the share options on voluntary basis. The number of exercisable share options was 11.724 million,
      and the exercise period was from 21 December 2019 to 20 December 2020.

      Pursuant to“the Resolution relating to Cancellation of Certain Share Options of the Company Granted but Not Yet Exercised
      under the 2018 Share Option Incentive Plan”considered and approved at the 30th Meeting of the 7th Session of the Board
      of the Company on 14 August 2020, 1.488 million share options that have been granted but not yet exercised by 23 Incentive
      Participants under the rst grant who resigned due to personal reasons and did not meet the incentive conditions are canceled.
      After the completion of the cancellation, the number of Incentive Participants for the first grant of the 2018 share options
      incentive scheme of the Company was adjusted from 258 to 235, while the number of share options under the first grant was
      adjusted from 18,928,900 to 17,444,100.

      Pursuant to“the Resolution relating to Cancellation of Certain Share Options of the Company Granted but Not Yet Exercised
      under the 2018 Share Option Incentive Plan”considered and approved at the 33rd Meeting of the 7th Session of the Board
      of the Company on 16 November 2020, 96,000 share options that have been granted but not yet exercised by 2 Incentive
      Participants under the rst grant who resigned due to personal reasons and did not meet the incentive conditions are canceled.
      After the completion of the cancellation, the number of Incentive Participants for the first grant of the 2018 share options
      incentive scheme of the Company was adjusted from 235 to 233, while the number of share options under the first grant was
      adjusted from 16,940,000 to 16,844,400.

      As at 31 December 2021, the number of share options exercised for the Period was 20,503,580 and the number of outstanding
      share options was 6,484,420.

 ② Pursuant to“the Resolution on the Grant of Share Options to Incentive Participants under the Reserved Grant”considered and
    approved at the 16th Meeting of the 7th Session of the Board of the Company on 23 September 2019, 23 September 2019 was
    set as the date of grant, on which 8.99 million share options were granted to 187 incentive participants at an exercise price of
    RMB10.47 per share option.

      Pursuant to“the Resolution in Relation to the Adjustment of the Quantity to be Granted and the List of Incentive Participants
      of the Reserved Grant under 2018 Share Options Incentive Scheme”considered and approved at the 17th Meeting of the 7th
      Session of the Board of the Company on 28 October 2019, the number of Incentive Participants for the Reserved Grant of
      share options was adjusted from 187 to 186, while the number of share options under the Reserved Grant was adjusted from
      8.99 million to 8.97 million.

      Pursuant to“the Resolution relating to Cancellation of Certain Share Options of the Company Granted but Not Yet Exercised
      under the 2018 Share Option Incentive Plan”considered and approved at the 30th Meeting of the 7th Session of the Board
      of the Company on 14 August 2020, 1.88 million share options that have been granted but not yet exercised by 28 Incentive
      Participants under the Reserved Grant who resigned due to personal reasons and did not meet the incentive conditions are
      canceled. After the completion of the cancellation, the number of Incentive Participants for the Reserved Grant of the 2018
      Share Options Incentive Scheme of the Company was adjusted from 186 to 158, while the number of share options under the




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     Reserved Grant was adjusted from 8.97 million to 7.09 million.

     Pursuant to“the Resolution on Fulfillment of Exercise Conditions for the First Exercise Period of the Reserved Grant under
     the 2018 Share Options Incentive Scheme”considered and approved at the 31st Meeting of the 7th Session of the Board of
     the Company on 27 August 2020, it was believed that the exercise conditions for the rst exercise period of the reserved grant
     under the Incentive Scheme had been achieved, and it was agreed that the incentive participants who had fullled the exercise
     conditions might exercise the share options on voluntary basis. The number of exercisable share options was 3,545,000, and
     the exercise period was from 23 September 2020 to 22 September 2021.

     Pursuant to“the Resolution relating to Cancellation of Certain Share Options of the Company Granted but Not Yet Exercised
     under the 2018 Share Option Incentive Plan”considered and approved at the 33rd Meeting of the 7th Session of the Board
     of the Company on 16 November 2020, 450,000 share options that have been granted but not yet exercised by 8 Incentive
     Participants under the Reserved Grant who resigned due to personal reasons and did not meet the incentive conditions are
     canceled. After the completion of the cancellation, the number of Incentive Participants for the reserved grant of the 2018 share
     options incentive scheme of the Company was adjusted from 158 to 150, while the number of share options under the reserved
     grant was adjusted from 4,616,500 to 4,166,500.

     As at 31 December 2021, the number of share options exercised for the Period was 4,326,286 and the number of outstanding
     share options was 2,153,714.

(2)Livzon Group, a subsidiary of the Company


      Total equity instruments granted during the Current Period by the Company (share)                                             -
      Total equity instruments exercised during the Current Period by the Company (share)                                 5,752,133
      Total equity instruments of the Company expired during the Current Period (share)                                           -
      Range of exercise price of share option of the Company outstanding and remaining term
                                                                                                                              Note 1
      of contract as at the end of the Period
      Range of exercise price of other equity instruments of the Company and remaining term
                                                                                                                              Note 2
      of contract as at the end of the Period


     Note 1: Share Option

 ① On 5 September 2018,“the Resolution on 2018 Share Options Incentive Scheme (Revised Draft) and its summary”, the
   “Resolution on Administrative Measures for Appraisal System of the 2018 Share Options Incentive Scheme of Livzon
    Pharmaceutical Group Inc.”and“the Resolution on the General Meeting For Granting Mandate to the Board to Deal with
     Matters Regarding the 2018 Share Options Incentive Scheme”were considered and approved at the 2018 Third Extraordinary
     General Meeting, the 2018 Third Class Meeting of A Shareholders and the 2018 Third Class Meeting of H Shareholders of
     Livzon Group. Pursuant to“the Resolution in Relation to the Adjustment of the List of Incentive Participants of the First Grant
     and the Quantity to be Granted for the First Grant under 2018 Share Options Incentive Scheme”and“the Resolution on the
     Related Matters of the First Grant of 2018 Share Options Incentive Scheme”considered and approved at the 19th Meeting of
     the 9th Session of the Board of Livzon Group on 11 September 2018, 11 September 2018 was set as the date of grant, on which
     17,475,500 Share Options were granted to 1,050 Incentive Participants at an exercise price of RMB47.01 per share option.

     Pursuant to“the Resolution relating to Cancellation of Certain Share Options under the 2018 Share Option Incentive Plan”
     considered and approved at the 32nd Meeting of the 9th Session of the Board of Livzon Group on 18 September 2019, 254,995
     share options that have been granted but not yet exercised by 17 Incentive Participants who resigned due to personal reasons
     and did not meet the incentive conditions are canceled. After the completion of the cancellation, the number of Incentive
     Participants for the rst grant of the 2018 share options incentive scheme of Livzon Group was adjusted from 1,050 to 1,033,




                                                                                                                                 271
      while the number of share options under the rst grant was adjusted from 22,718,150 to 22,463,155.

      Pursuant to“the Resolution relating to Cancellation of Certain Share Options under the 2018 Share Option Incentive Plan”
      considered and approved at the 4th Meeting of the 10th Session of the Board of Livzon Group on 23 October 2020, 162,912
      share options under the rst exercise period held but not yet exercised by 55 Incentive Participants and 1,535,765 share options
      granted and no longer meeting the exercising conditions to 129 Incentive Participants who had resigned due to personal
      reasons and were therefore no longer qualified for the incentive are canceled. After the completion of the cancellation, the
      number of Incentive Participants for the rst grant of the 2018 Share Options Incentive Scheme of Livzon Group was adjusted
      from 1,033 to 904, while the number of share options under the rst grant was adjusted from 22,463,155 to 20,764,478.

      Pursuant to“Resolution relating to Cancellation of Certain Share Options under the 2018 Share Option Incentive Plan”
      considered and approved at the the 25th meeting of the tenth session of the Board of Livzon Group on 10 November 2021,
      323,274 share options under the second exercise period held but not yet exercised by 80 Incentive Participants and 673,422
      share options granted and no longer meeting the exercising conditions to 107 Incentive Participants who were no longer
      qualied for the incentive are cancelled. After the completion of the cancellation, the number of Incentive Participants for the
      first grant of the 2018 Share Options Incentive Scheme of the Company was adjusted from 904 to 797, while the number of
      share options under the rst grant was adjusted from 20,764,478 to 19,767,782.

      As at 31 December 2021, the number of share options exercised was 14,598,360 and the number of outstanding share options
      was 5,169,422.

 ② Pursuant to“the Resolution relating to Relevant Issues concerning the Reserved Grant under the 2018 Share Options Incentive
    Scheme”considered and approved at the 31st Meeting of the 9th Session of the Board of Livzon Group on 28 August 2019,
    the Board approved 28 August 2019 as the date of grant, on which 2,535,000 share options were granted to 145 Incentive
    Participants and the exercise price was RMB28.87 per A share.

      Pursuant to“the Resolution relating to Adjusting the List of Incentive Participants under the Reserved Grant of the 2018 Share
      Options Incentive Scheme”considered and approved at the 32nd Meeting of the 9th Session of the Board of Livzon Group
      on 18 September 2019, the number of Incentive Participants under the reserved grant of the share option incentive plan was
      adjusted from 145 to 170.

      On 28 October 2019, the Reserved Grant of the share options has completed registration. During the process of registration, 1
      Incentive Participant was no longer qualied for incentive due to his resignation, and 2 Incentive Participants voluntarily gave
      up the Share Options to be granted by Livzon Group due to personal reasons. Therefore, the number of Incentive Participants
      under the Reserved Grant is adjusted from 170 to 167, and the total number of Share Options under the Reserved Grant is
      adjusted from 2,535,000 to 2,524,500.

      Pursuant to“the Resolution relating to Cancellation of Certain Share Options under the 2018 Share Option Incentive Plan”
      considered and approved at the 4th Meeting of the 10th Session of the Board of Livzon Group on 23 October 2020, 309,900
      share options granted and no longer meeting the exercising conditions to 10 incentive participants who had resigned due to
      personal reasons and were therefore no longer qualied for the incentive are canceled. After the completion of the cancellation,
      the number of Incentive Participants under the Reserved Grant of the 2018 Share Options Incentive Scheme of Livzon Group
      was adjusted from 167 to 157, while the number of share options under the Reserved Grant was adjusted from 2,524,500 to
      2,214,600.

      Pursuant to“Resolution relating to Cancellation of Certain Share Options under the 2018 Share Option Incentive Plan”
      considered and approved at the the 25th meeting of the tenth session of the Board of Livzon Group on 10 November 2021,
      31,150 share options under the first exercise period held but not yet exercised by 7 Incentive Participants and 129,400 share
      options granted and no longer meeting the exercising conditions to 18 incentive participants who were no longer qualied for
      the incentive are cancelled. After the completion of the cancellation, the number of Incentive Participants under the Reserved
      Grant of the 2018 Share Options Incentive Scheme of the Company was adjusted from 157 to 139, while the number of share
      options under the Reserved Grant was adjusted from 2,214,600 to 2,054,050.

      As at 31 December 2021, the number of share options exercised was 1,226,494 and the number of outstanding share options



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   was 827,556.

   Note 2: Other equity incentives

   Pursuant to“the Resolution on the Disposal of Certain Equity of a Holding Subsidiary and Connected Transaction”considered
   and approved at the 34th Meeting of the 9th Session of the Board of Livzon Group on 8 November 2019, it was agreed that
   9.5% equity interests (totally 8,382,100 shares) in Zhuhai Livzon Diagnostics Inc. ( 珠 海 丽 珠 试 剂 股 份 有 限 公 司 ) held by
   Livzon Group shall be transferred to Zhuhai Liying Investment Management Partnership (Limited Partnership) ( 珠 海 丽 英
   投 资 管 理 合 伙 企 业( 有 限 合 伙 )) at the consideration of RMB21,122,892. Pursuant to the Assets Appraisal Report on the
   Valuation of the Shareholders'

   Equity as a Whole of Zhuhai Livzon Diagnostics Inc. in Relation to the Proposed Equity Transfer by Livzon Pharmaceutical
   Group Inc. (Huaya Zhengxin Appraisal Report [2019] No. A02-0011), the valuation of the shareholders’equity as a whole
   of Zhuhai Livzon Diagnostics Inc. as at 30 June 2019 was RMB647.3075 million, and the above equity transfer price was
   lower than its fair value, therefore it constitutes a share-based payment. The total share-based payment of the transaction is
   RMB40.4017 million, which should be amortized within 5 years according to the partnership agreement and share incentive
   expenses were recognised due to the share-based payment as a result of the change in the shareholding of the shareholders of
   Zhuhai Liying Investment Management Partnership (Limited Partnership).

   Pursuant to“the Resolution on the Implementation of Employee Equity Incentive Scheme by a Holding Subsidiary”
   considered and approved at the 34th Meeting of the 9th Session of the Board of Livzon Group on 8 November 2019, the
   total number of shares of new issuance by Zhuhai Livzon Diagnostics Inc. for implementation of employee equity incentive
   scheme shall not be more than 4,643,839 shares, and the scheme participants shall contribute a total of RMB11,702,474.28 to
   directly subscribe for the above shares or indirectly subscribe for the such shares through the holding of the limited partnership
   shares of the employee shareholding platform. In December 2019, pursuant to the Capital Increase Agreement of Zhuhai
   Livzon Diagnostics Inc., the total shares of Zhuhai Livzon Diagnostics Inc. increased from 88,232,932 shares to 92,876,771
   shares with par value of RMB1 per share. The increased number of shares were subscribed for by Zhuhai Haoxun Enterprise
   Management Consulting Partnership (Limited Partnership) ( 珠海豪汛企业管理咨询合伙企业(有限合伙)), Zhuhai Yichen
   Enterprise Management Consulting Partnership (Limited Partnership) ( 珠海熠臣企业管理咨询合伙企业(有限合伙)) and
   Zhuhai Qijing Enterprise Management Consulting Partnership (Limited Partnership) ( 海启靖企业管理咨询合伙企业(有限
   合 伙 )) at the consideration of RMB11,702,474. The subscription price is lower than the fair value, therefore it constitutes a
   share-based payment. The total share-based payment of the transaction is RMB20,709,000, which should be amortized within
   5 years according to the Partnership Agreement, and share incentive expenses were recognized due to the share-based payment
   as a result of the change in the shares/shareholding of the shareholders of Zhuhai Livzon Diagnostics Inc.

   On 31 August 2021, the general meeting of LivzonBio considered and approved the Equity Incentive Scheme of Zhuhai
   Livzon Biotechnology Co., Ltd. ( 珠 海 市 麗 珠 生 物 醫 藥 科 技 有 限 公 司 ), granting 66,666,667 restricted shares of Livzon
   Biologics to incentive participants, among which 42 million shares were granted in the rst batch and 24,666,667 shares were
   reserved. Incentive participants indirectly subscribed for the above shares through the holding of the limited partnership shares
   of the employee shareholding platform. The subscription price is lower than the fair value, therefore it constitutes a share-based
   payment. The total share-based payment of the transaction is RMB33.6 million, which should be amortized during the lock-up
   period according to the Equity Incentive Scheme of LivzonBio and the Grant Agreement and RMB6,533,300 was amortized in
   2021.


2. Equity settled share-based payments
   √ Applicable □ N/A
                                                                                                          Unit: Yuan Currency: RMB
    Determination on fair value of equity instruments as the date of grant                      Black-Scholes Model, market price
    Basis for determining quantity of exercisable equity instruments                                                               -
    Reasons for signicant discrepancies between estimate for the Period and Previous Period                                     Nil
    Accumulated amount of equity settled share-based payments included in capital reserve                           169,298,762.65
    Total expense recognised for equity settled share-based payments for the Period                                  34,527,082.60


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  3. Cash settled share-based payments
      □ Applicable √ N/A


XII COMMITMENTS AND CONTINGENCIES

  1. Significant commitments
      √ Applicable □ N/A

      Signicant commitments to outsiders as of the balance sheet data, and their nature and amount

(1)Capital commitments


                                                                              Balance at the End           Balance at the Beginning
      Contracted but not recognised in the nancial statement
                                                                                   of the Period                       of the Period
      Commitments in relation to acquisition of long-term assets                 322,611,032.41                     673,900,118.24
      Commitments in relation to external investment                               8,000,000.00                                0.00
      Commitments in relation to research and development
                                                                                 309,313,880.64                                0.00
      expenditures


(2)Operating lease commitments
     As at 31 December 2021, the Company signed the non-cancellable operating leases as follows:


      Minimum lease payments under non-cancellable operating leases payable                        Balance at the End of the Period
      Within one year from the balance sheet date                                                                    21,295,233.00
      In the second year from the balance sheet date                                                                 13,186,526.27
      In the third year from the balance sheet date                                                                   9,161,217.34
      Subsequent years                                                                                                3,535,180.85
      Total                                                                                                          47,178,157.46


(3)Other commitments
     Nil.

(4)Performance of previous commitments
     The Company has duly performed the capital expenditure commitments and the operating lease commitments as at 31
     December 2021 and the other commitments.

  2. Contingencies
 (1). Signicant contingencies as of the balance sheet date
      □ Applicable √ N/A

 (2). Please also make explanations thereof if the Company has no signicant contingency to be disclosed:
      √ Applicable □ N/A

      As at 31 December 2021, there were no signicant contingencies required to be disclosed by the Company.

  3. Others
      □ Applicable √ N/A


XIII Events after the Balance Sheet Date

  1. Significant non-adjustment events
      □ Applicable √ N/A


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  2. Profit distribution
     √ Applicable □ N/A
                                                                                                             Unit: Yuan Currency: RMB
      Prots or dividends to be distributed                                                  283,540,214.25
      Prots or dividends declared after deliberation and approval


     Note: The amount of cash dividends proposed in 2021 (tax included) listed above are calculated based on the company's total
     share capital at the end of 2021 minus the ending balance in the company's special account for share repurchase. The actual
     dividends paid shall be based on the implementation of the company's 2021 prot distribution plan, in which the calculation is
     based on the company's total share capital on the plan's date of record minus the total shares in the company's special securities
     account for share repurchase.

     On 29 March 2022, the Company held the 9th meeting of the eighth session of the Board of the Company and passed the
     resolution of 2021 annual profit distribution plan. It is expected to distribute cash dividend of RMB 1.50(tax inclusive) for
     every 10 shares to all Shareholders of the Company, based on the Company’s total share capital (excluding total number of
     shares in the Company's special securities accoun) as at the registration date of shareholding as determined by implementation
     of the 2021 annual prot distribution plan. The remaining undistributed prots are carried forward to distribution in subsequent
      years.

      The above mentioned profit distribution plan shall be submitted to the annual general meeting of 2021 of the Company for
      consideration and approval.


  3. Sales returns
     □ Applicable √ N/A


  4. Descriptions of other events after the balance sheet date
     √ Applicable □ N/A

(1)Exercise of share options

     As of 29 March 2022, shares option involving 4,005,170 shares were exercised by the incentive participants and the share
     capital of the Company was changed to 1,911,733,078 shares.

(2)Matters about share repurchase

     Pursuant to the Resolution on Share Repurchase Scheme by Way of Centralized Price Bidding and other resolutions considered
     and approved at the 6th Meeting of the 8th Session of the Board on 6 December 2021, it was approved that the Company
     repurchased company shares by way of centralized price bidding through the trading system of Shanghai Stock Exchange;
     the total amount of repurchase funds should be no less than RMB300 million (inclusive) and no more than RMB600 million
     (inclusive); the repurchase price should be no more than RMB15/share (inclusive), and all the shares repurchased shall be
     cancelled for reducing its registered capital. The repurchase funds come from the company's own funds or self-raised funds.
     The repurchase term should be no more than 12 months from the date when the repurchase scheme was approved by the
     General Meeting of the Company, from Decmber 23, 2021 to December 22, 2022.

     Pursuant to the Resolution on Share Repurchase Scheme by Way of Centralized Price Bidding and other resolutions considered
     and approved at he 2021 Fifth Extraordinary General Meeting of the Company on 23 December 2021.

     As of 29 March 2022, the Company cumulatively repurchased 20,942,771 shares, the total amount paid was
     RMB249,971,630.73 (including transaction costs).

     As of 29 March 2022, the Company has no other events that needed to be disclosed after the balance sheet date.




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XIV Other significant events
      √ Applicable □ N/A


 (I) Important supplier
      Jiaozuo Xincheng Huai Medicine Co., Ltd. (hereinafter referred to as“Xincheng Company”) is a supplier of Chinese herbs
      of the Company. The Company purchased Chinese herbs of RMB 21.55 million (tax inclusive) from Xincheng Company
      during the current period, accounting for 100% of the total amount of purchases of Chinese herbs (excluding Livzon Group).
      Xincheng Company delivered commodities to the Company according to the Purchase Contract of the Company and issued
      VAT special invoices after acceptance by the Company. As at 31 December 2021, the balance of prepayment of the Company
      to Xincheng Company was RMB12,199,251.14.


 (II) Adjustment to the use of proceeds from Fund-Raising in Investment Projects
 (1) The Company

      Pursuant to“the Resolution on Extension of Certain Projects Invested with Proceeds”considered and approved at the 44th
      Meeting of the 7th Session of the Board of the Company on 29 March 2021, it was agreed that the Company extended the time
      to start construction of the project of Zhuhai Health Industry Base to the second half of 2021. The specific commencement
      time was up to the construction completion time of municipal supporting works on the project construction site.

      Pursuant to the“Resolution on Change of Certain Projects Invested with Proceeds”considered and approved at the 8th
      meeting of the 8th Session of the Board of the Company on 24 January 2022, it was agreed that Zhuhai Health Industry Base
      Construction Project was changed to the New Product R&D Project, Haibin Pharma Pingshan Pharmaceutical Industrialization
      Base Expansion Project and the Information Platform Construction Project. The resolution was approved at the 2022 1st
      extraordinary general meeting of the Company on 11 February 2022.

      Before the alteration of the projects invested with the Proceeds is as follows:
                                                                                                                   Unit: 10,000 Yuan
                                                                              Total amount              Use of          Balance of
                                                          Total amount
       Project name                                                            of proceeds    proceeds as at 31   proceeds as at 31
                                                          of investment
                                                                                investment     December 2021       December 2021
       Zhuhai Health Industry Base Construction
                                                              98,066.84           76,974.02           3,386.29           73,587.73
       Project(珠海大健康产业基地建设项目)
        Haibin Pharma Pingshan Pharmaceutical
        Industrialization Base Project                      125,471.35            90,000.00          66,745.58           23,254.42
      (海滨制药坪山医药产业化基地目)
       Total                                                223,538.19          166,974.02           70,131.87           96,842.15


      Given the facts that the“Zhuhai Health Industry Base Construction Project”has been postponed for several times for not
      meeting the conditions for commencement, and the market environment and the Company's business situation have changed,
      which resulted in changes in the project feasibility, that the Company has an urgent need of funds for R&D investment and
      other projects, and that other financing channels are time-consuming and costly, the Company changed the aforementioned
      project to the New Product R&D Project, Haibin Pharma Pingshan Pharmaceutical Industrialization Base Expansion Project
      and the Information Platform Construction Project. See below for details:




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                                                                                                                           Unit: 10,000 Yuan
                         Before alteration                                                  After alteration
                                                 Total amount                                                                Total amount
                                Total amount                                                            Total amount
    Project name                                  of proceeds        Project name                                             of proceeds
                                of investment                                                           of investment
                                                   investment                                                                  investment
                                                                     New Product R&D Project
                                                                                                           110,000.00           54,587.73
                                                                     ( 新产品研发项目 )
                                                                     Haibin Pharma Pingshan
     Zhuhai Health Industry
                                                                     Pharmaceutical Industrialization
     Base Construction
                                                                     Base Expansion Project                    18,139.39        16,000.00
     Project                        98,066.84       76,974.02
                                                                     ( 海滨制药坪山医药产业化基地
   (珠海大健康产业基地
                                                                     扩建项目 )
     建设项目)
                                                                     The Information Platform
                                                                     Construction Project                       3,000.00          3,000.00
                                                                     ( 信息化平台建设项目 )
    Total                           98,066.84       76,974.02        Total                                 131,139.39           73,587.73


    The details of alteration of the projects invested as follows:

1) The New Product R&D Project

    The total investment amount of the project is RMB 1,100,000,000, in which RMB 545,877,300 is raised, mainly for the
    research and development of inhalation preparations, complex injections, and new drug delivery devices among others. In
   particular, the investment is used to acquire R&D equipment, pre-clinical and clinical R&D inputs. Main products involved
   in this project are: 1) respiratory drugs: the main purpose of the project as a part of the Company's strategic layout in the
   respiratory drug market, in a bid to increase sources of profit and enhance the Company's comprehensive competitiveness in
   the pharmaceutical market; 2) complex injections: mainly micronano injections. The Company has built a complex injection
   technology development platform, specializing in the development of special injection products such as nanocrystals,
   microcrystals, liposomes and emulsions. The micronano preparations proposed with this platform will be developed based
   on existing drugs with exact clinical value to further expand the clinical use of the drug; and (3) new drug delivery devices:
   to be developed based on the progress of R&D of drugs for respiratory diseases, so as to improve the industrial chain of core
   products, and enhance the added value and core competitiveness of products to be marketed.

2) Haibin Pharma Pingshan Pharmaceutical Industrialization Base Expansion Project

    The total investment amount of this project is RMB 181,393,900, in which RMB 160,000,000 is raised. Expanded from the
    Haibin Pharma Pingshan Pharmaceutical Industrialization Base Expansion Project, this project established new production
    lines of Tobramycin Solution for Inhalation, Fluticasone Propionate Suspension for Inhalation, among others and expanded
    existing production lines of Budesonide Suspension for Inhalation and Levosalbutamol Hydrochloride Nebuliser Solution.
    This project is implemented for two key reasons: 1) New products are to be marketed, which requires related production lines.
    With inhalation preparations incorporated in its key layout in recent years, the Company has continuously invested in the
    R&D of several new products with high clinical value and broad market space. As new products like Tobramycin Solution for
    Inhalation and Fluticasone Propionate Suspension for Inhalation are to be marketed, related production lines are necessary
    to make preparation for commercial production. 2) The capacity is unable to meet demand of some products: Budesonide
    Suspension for Inhalation was involved in the fifth batch of national centralized drug procurement in June 2021, and will be
    supplied to 7 provincial public hospitals in the country, meeting 70% of the drug needs according to policies. Levosalbutamol
    Hydrochloride Nebuliser Solution is the first approved exclusive generic drug in China. So far, no originator manufacturers
    or other generic drug manufacturers have been approved for market in China. However, the market demand is huge. The
    original capacity of the above two products is unable to meet such market demand, making capacity expansion a must.3. The
    Information Platform Construction Project




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 3) The Information Platform Construction Project

      The total investment amount of this project is RMB 30,000,000, in which RMB 30,000,000 is raised. The investment is used to
      purchase information management software and hardware as well as computer room facilities. The project planned to upgrade
      and improve: (1) the information infrastructure of existing information management system, including disaster recovery and
      infrastructure of the server, and security equipment; (2) nancial management system, including nancial sharing system and
      tax administration system; (3) group management and control system, including HR system and SAP system.

 (2) Livzon Group, a subsidiary of the Company

      On 22 March 2021, the Board of Livzon Group considered and approved“the Resolution on Adjustment to Certain Projects
      Invested with Proceeds” to adjust the“Project for Indepth Development and Industrialization Upgrade of Innovative
      Ilaprazole Series, after which the remaining proceeds to be invested in the project is RMB203,996,700 and the project
      is expected to be ready for its intended use by 31 December 2024. The expected annual investment amount will be
      RMB119,924,000, RMB54,676,000, RMB16,000,000 and RMB13,396,700 in the next four years.


(III) Leases
      The Company had adopted a simplified approach for short-term leases and leases of low value assets and did not recognize
      right-of-use assets and lease liabilities. The expense of short-term leases, leases of low value assets and variable lease
      payments not included in the measurement of lease liabilities are included in the expenses in the current period as follows:


      Item                                                                                                             For the period
      Short-term leases                                                                                                 7,454,872.21
      Leases of low value assets                                                                                                 0.00
      Total                                                                                                             7,454,872.21


(IV) Medium to Long-term Business Partner Share Ownership Scheme
 (1) The Company

      On 29 June 2021, the 2021 second extraordinary general meeting of the Company reviewed and approved“the Resolution on
      the First Phase Ownership Scheme under Medium to Long-term Business Partner Share Ownership Scheme of the Company
      (Draft) and its Summary”. On 4 August 2021, the First Phase Ownership Scheme under Medium to Long-term Business
      Partner Share Ownership Scheme of the Company purchased a total of 2,430,800 shares of the Company through the“Joincare
      Pharmaceutical Group Industry Co., Ltd.-the First Phase Ownership Scheme under Medium to Long-term Business Partner
      Share Ownership Scheme-Employee Ownership Scheme No. 1 Single Asset Management Plan of Guosen Securities and
      Joincare” 健康元药业集团股份有限公司-中长期事业合伙人持股计划之第一期持股计划 - 国信证券健康元员工持
      股 1 号 单 一 资 产 管 理 计 划 ) by way of non-trade transfer, representing 0.12% of total share capital of the Company, with an
      average transaction price of RMB12.75 per share and a transaction amount of RMB30,992,700.00. The purchase of shares
      under the First Phase Ownership Scheme under Medium to Long-term Business Partner Share Ownership Scheme of the
      Company has been completed, and these shares will be locked up for 36 months (from 4 August 2021 to 3 August 2024) as
      required.

 (2) Livzon Group, a subsidiary of the Company

      On 6 May 2021, the 2021 second extraordinary general meeting of Livzon Group reviewed and approved relevant resolutions
      including the Resolution on the First Phase Ownership Scheme under Medium to Long-term Business Partner Share
      Ownership Scheme of the Company (Draft) and its Summary. On 26 May 2021, the First Phase Ownership Scheme under
      Medium to Long-term Business Partner Share Ownership Scheme of Livzon Group purchased a total of 2,348,960 shares of
      the Company through the“CITIC Securities – the First Phase Business Partner Share Ownership Scheme of Livzon Group
      – Medium and Long-term Business Partner Employee Ownership Scheme No. 1 Single Asset Management Plan of CITIC
      Securities and Livzon Group” 中信证券-丽珠集团事业合伙人持股计划第一期-中信证券丽珠集团中长期事业合伙



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      人 员 工 持 股 计 划 1 号 单 一 资 产 管 理 计 划 ) by way of centralized price bidding, representing 0.25% of total share capital of
      Livzon Group, with an average transaction price of RMB49.92 per share and a transaction amount of RMB117,268,338.21.
      The purchase of shares under the First Phase Ownership Scheme under Medium to Long-term Business Partner Share
      Ownership Scheme of Livzon Group has been completed, and these shares will be locked up for 36 months (from 27 May
      2021 to 26 May 2024) as required.

      As at the date of the balance sheet, other than the matters mentioned above, the Company has no other significant events that
      need to be disclosed.


XV Notes to the Key Components of Financial Statements of the Parent Company

  1. Bills receivables

                                                                      Balance at the End of the Period                             Balance at the Beginning of the Period
                                                                              Provision                                                           Provision
       Type of bill
                                                      Book balance              for bad           Carrying value           Book balance             for bad           Carrying value
                                                                                  debts                                                               debts
       Bank acceptance bills                        374,296,302.21                       0.00 374,296,302.21              53,571,233.65                   0.00            53,571,233.65
       Commercial acceptance bill                                  0.00                  0.00                   0.00                    0.00              0.00                        0.00
       Total                                        374,296,302.21                       0.00 374,296,302.21              53,571,233.65                   0.00            53,571,233.65


(1)Bills receivables that were pledged at the End of the Period


       Type of bill                                                                                                              Pledged amount at the End of the Period
       Bank acceptance bills                                                                                                                                          285,562,300.65


(2)Bills receivable endorsed or discounted at the End of the Period but not yet mature at the date of balance sheet


                                                                                                 Amount derecognised at                           Amount not derecognised at
       Item
                                                                                                   the End of the Period                               the End of the Period
       Bank acceptance bills endorsed but not yet mature                                                       19,391,291.49
       Bank acceptance bills discounted but not yet mature                                                     22,858,934.79
       Total                                                                                                   42,250,226.28


(3)There were no bills transferred into accounts receivables for non-performance by the issuer at the End of the Period.

(4)Classication by the method of bad debt provision

                                                      Balance at the End of the Period                                           Balance at the Beginning of the Period
                                            Book balance         Provision for bad debts                           Provision for bad debts       Book balance         Provision for bad debts
       Type                                                                                     Book balance
                                                    Percentage               Percentage                                        Percentage               Percentage
                                         Amount                  Amount                             Amount          Amount                   Amount                           Carrying value
                                                           (%)                      (%)                                               (%)                       (%)
       Provision for bad debt on
       an individual basis
       Provision for bad debt on
                                   374,296,302.21      100.00       0.00           0.00     374,296,302.21     53,571,233.65       100.00      0.00           0.00            53,571,233.65
       a collective basis
       Of which:
        Bank acceptance bills     374,296,302.21      100.00       0.00           0.00     374,296,302.21     53,571,233.65       100.00      0.00           0.00            53,571,233.65
       Total                       374,296,302.21      100.00       0.00           0.00     374,296,302.21     53,571,233.65       100.00      0.00           0.00            53,571,233.65




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(5)Provision for bad debt made, recovered or reversed during the Period
     Nil

(6)There are no bills receivables actually written-o for the Period.

  2. Accounts receivables
 (1). Disclosure using the aging analysis method
      √ Applicable □ N/A
                                                                                                                                                       Unit: Yuan Currency: RMB
       Aging                                                                                                                                Balance at the End of the Period
       Within 1 year                                                                                                                                                538,967,095.90
       1-2 years                                                                                                                                                           1,410,787.21
       2-3 years                                                                                                                                                            733,293.23
       3-4 years                                                                                                                                                            388,712.49
       4-5 years                                                                                                                                                            360,879.34
       Over 5 years                                                                                                                                                        7,723,623.65
       Total                                                                                                                                                        549,584,391.82


 (2). Classication by the method of bad debt provision
      √ Applicable □ N/A
                                                                                                                                                       Unit: Yuan Currency: RMB
                                                          Balance at the End of the Period                                       Balance at the Beginning of the Period
                                          Book balance              Provision for bad debts                          Book balance                Provision for bad debts
       Type                                                                  Expected                                                                     Expected
                                                 Percentage                                   Carrying value                  Percentage                                     Carrying value
                                      Amount                         Amount credit loss                            Amount                         Amount credit loss
                                                        (%)                                                                          (%)
                                                                              rate (%)                                                                     rate (%)
       Provision for bad debt
                                   771,300.68            0.14     771,300.68        100.00             0.00    1,120,703.15          0.29     1,120,703.15       100.00                0.00
       on an individual basis
       Of which:
       Amount due from
                                   771,300.68            0.14     771,300.68        100.00             0.00    1,120,703.15          0.29     1,120,703.15       100.00                0.00
       domestic customers
       Amount due from
                                          0.00           0.00            0.00         0.00             0.00           0.00           0.00             0.00          0.00               0.00
       overseas customers
       Provision for bad debt
                                548,813,091.14       99.86 13,270,020.90              2.42 535,543,070.24 386,433,230.10            99.71 16,938,369.88             4.38     369,494,860.22
       on a collective basis
       Of which:
       Amount due from
                                548,813,091.14       99.86 13,270,020.90              2.42 535,543,070.24 386,433,230.10            99.71 16,938,369.88             4.38     369,494,860.22
       domestic customers
       Amount due from
                                          0.00           0.00            0.00         0.00             0.00            0.00          0.00             0.00          0.00               0.00
       overseas customers
       Total                    549,584,391.82           100 14,041,321.58            2.55 535,543,070.24 387,553,933.25         100.00 18,059,073.03               4.66     369,494,860.22


      Provision for bad debt on an individual basis:
      √ Applicable □ N/A
                                                                                                                                                       Unit: Yuan Currency: RMB
                                                                                      Balance at the End of the Period
       Name                                                            Provision for bad               Expected credit loss
                                            Book balance                                                                                     Reason for provision made
                                                                                   debts                          rate (%)
       Payment for goods                         771,300.68                     771,300.68                             100.00               Not expected to be recoverable
       Total                                     771,300.68                     771,300.68                             100.00                                   /




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    Provision for bad debt on an individual basis:
    □ Applicable √ N/A

    Provision for bad debt on a collective basis:
    √ Applicable □ N/A

    Item on a collective basis: Due from domestic customers
                                                                                                               Unit: Yuan Currency: RMB
                                                                          Balance at the End of the Period
     Aging
                                              Accounts receivables             Provision for bad debts             Carrying Value (%)
     Within 1 year                                    538,967,095.90                     5,259,670.96                             0.98
     1-2 years (including 2 years)                      1,410,787.21                       150,539.36                           10.67
     2-3 years (including 3 years)                        733,293.23                       239,987.97                           32.73
     3-4 years (including 4 years)                        103,939.29                        81,969.65                           78.86
     4-5 years (including 5 years)                        300,612.74                       240,490.19                           80.00
     Over 5 years                                       7,297,362.77                     7,297,362.77                          100.00
     Total                                            548,813,091.14                    13,270,020.90                             2.42


    Standards of provision for bad debts made by portfolio and descriptions thereof:
    □ Applicable √ N/A

    If the provision for bad debts is made in accordance with the general model of expected credit losses, please refer to other
    receivables disclosure:
    □ Applicable √ N/A

(3). Provision for bad debts
     √ Applicable □ N/A
                                                                                                               Unit: Yuan Currency: RMB
                                Balance at the                         Changes for the current period                       Balance at
     Item                        Beginning of                         Recovery                                 Other        the End of
                                                       Provision                    Removal/write-o
                                   the Period                        or reversal                             changes        the Period
     Accounts receivables       18,059,073.03       1,857,142.19            0.00         5,874,893.64           0.00     14,041,321.58
     Total                      18,059,073.03       1,857,142.19            0.00         5,874,893.64           0.00     14,041,321.58


    As at 31 December 2021 and 31 December 2020, the Company had no accounts receivables that are past due but not impaired.
    Signicant recovery or reversal of bad debt provision for the current period:
    □ Applicable √ N/A

(4). Accounts receivable actually written o for the current period
     √ Applicable □ N/A


     Item                                                                                                          Amount written o
     Accounts receivable actually written o                                                                               5,874,893.64


    Signicant accounts receivables written o.
    □ Applicable √ N/A




                                                                                                                                   281
(5). The top ve balances of accounts receivable by debtors as at the End of the Period
     √ Applicable □ N/A
                                                                                                           Unit: Yuan Currency: RMB
                                    Balance at the End       Proportion in total balance of account      balance for bad debts as at
      Name of company
                                         of the Period      receivables for the End of the Year (%)           the End of the Period
      Unit 1                            17,455,040.43                                          3.18                     174,550.40
      Unit 2                            15,755,536.96                                          2.87                     157,555.37
      Unit 3                            14,641,981.20                                          2.66                     146,419.81
      Unit 4                            14,588,288.80                                          2.65                     145,882.89
      Unit 5                            14,396,812.58                                          2.62                     143,968.13
      Total                             76,837,659.97                                        13.98                      768,376.60


      Other descriptions:
      The total of the top five balances of accounts receivable by debtors as at the End of the Period was RMB76,837,659.97 for
      the Period, representing13.98% of the total balance of account receivables for the End of the Period, the aggregate balance of
      corresponding provisions for bad debts as at the End of the Period was RMB768,376.60.

(6). Derecognised accounts receivables in the Company due to the transfer of nancial assets.
     □ Applicable √ N/A

(7). Amount of assets or liabilities for which accounts receivable have been transferred but involvement continues in the Company.
     □ Applicable √ N/A

      Other descriptions:
      □ Applicable √ N/A


 3. Other receivables
      Line items
      √ Applicable □ N/A
                                                                                                           Unit: Yuan Currency: RMB
      Item                                         Balance at the End of the Period          Balance at the Beginning of the Period
      Dividend receivables                                         814,041,000.00                                    69,999,500.00
      Other receivables                                            322,196,811.25                                   306,776,204.09
      Total                                                      1,136,237,811.25                                   376,775,704.09


      Other descriptions:
      □ Applicable √ N/A

(1). Dividend receivables
     Dividend receivables
     √ Applicable □ N/A
                                                                                                           Unit: Yuan Currency: RMB
      Item                                         Balance at the End of the Period          Balance at the Beginning of the Period
      Topsino                                                      749,999,500.00                                    49,999,500.00
      Haibin Pharma                                                 44,041,500.00                                              0.00
      Fenglei Electric Power                                        20,000,000.00                                    20,000,000.00
      Provision for bad debts                                                 0.00                                             0.00
      Total                                                        814,041,000.00                                    69,999,500.00




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                                                                                                                      2021


     Other receivables
(1). Disclosure by aging
     √ Applicable □ N/A
                                                                                                        Unit: Yuan Currency: RMB
     Aging                                                                                      Balance at the End of the Period
     Subtotal within 1 year                                                                                     321,955,080.06
     1-2 years                                                                                                       149,812.10
     2-3 years                                                                                                       206,676.00
     3-4 years                                                                                                       126,228.36
     4-5 years                                                                                                        20,000.00
     Over 5 years                                                                                                 19,085,586.00
     Provision for bad debts                                                                                     -19,346,571.27
     Total                                                                                                      322,196,811.25


(2). Disclosure by nature of the amount
     √ Applicable □ N/A
                                                                                                        Unit: Yuan Currency: RMB
     Item                                            Balance at the End of the Period     Balance at the Beginning of the Period
     Other receivables of each company
                                                                       294,833,504.86                           209,567,199.87
     within the scope of combination
     Capital reduction                                                  24,078,925.22                            92,347,581.27
     Treasury bonds and Margin                                          17,968,386.04                            18,982,036.71
     External entities balances                                          3,763,793.73                               2,074,984.69
     Margin                                                               848,272.56                                1,452,703.18
     Others                                                                 50,500.11                               3,517,018.63
     Total                                                             341,543,382.52                           327,941,524.35


(3). Provision made for bad debts
     √ Applicable □ N/A
     As at the End of the Period, provision for bad debts at step 1:


                                                                     Expected credit
                                                                     losses rate over Provision for
     Type                                               Book balance                                Carrying value Reason
                                                                         the next 12     bad debts
                                                                         months (%)
     Provision for bad debt on an individual basis     24,078,925.22               0.00      0.00   24,078,925.22
                                                                                                                  Expected
     Capital reduction                                 24,078,925.22               0.00      0.00   24,078,925.22 to be
                                                                                                                  recoverable
     Provision for bad debt on a collective basis     294,833,504.86               0.00      0.00 294,833,504.86
                                                                                                                 Expected
     Other receivables of each company within
                                                      294,833,504.86               0.00      0.00 294,833,504.86 to be
     the scope of combination
                                                                                                                 recoverable
     Total                                            318,912,430.08               0.00      0.00 318,912,430.08




                                                                                                                             283
      As at the End of the Period, provision for bad debts at step 2:


                                                                        Expected credit
                                                                                            Provision for       Carrying
      Type                                              Book balance     losses rate over                                Reason
                                                                                               bad debts           value
                                                                        the lifetime (%)
      Provision for bad debt on an individual basis
      Provision for bad debt on a collective basis      4,662,566.40              29.56     1,378,185.23     3,284,381.17
      Receivable deposits                                 877,102.56              17.99      157,778.54       719,324.02
      Other receivables                                 3,785,463.84              32.24     1,220,406.69     2,565,057.15
      Total                                             4,662,566.40              29.56     1,378,185.23     3,284,381.17


      As at the End of the Period, provision for bad debts at step 3:


                                                                        Expected credit
                                                                                            Provision for       Carrying
      Type                                              Book balance     losses rate over                                Reason
                                                                                               bad debts           value
                                                                        the lifetime (%)
      Provision for bad debt on an individual basis    17,968,386.04             100.00 17,968,386.04                0.00
                                                                                                                          Not
                                                                                                                          expected
      National debt and Margin                         17,968,386.04             100.00 17,968,386.04                0.00
                                                                                                                          to be
                                                                                                                          recoverable
      Provision for bad debt on a collective basis               0.00               0.00            0.00             0.00
      Total                                            17,968,386.04             100.00 17,968,386.04               0.00


      As at 31 December 2020, provision made for bad debts:
      As at 31 December 2020, provision for bad debts at step 1:


                                                                        Expected credit
                                                                        losses rate over Provision for
      Type                                              Book balance                                        Carrying value Reason
                                                                            the next 12     bad debts
                                                                            months (%)
      Provision for bad debt on an individual basis    92,347,581.27                0.00           0.00     92,347,581.27
                                                                                                                          Expected
      Capital reduction                                92,347,581.27                0.00           0.00     92,347,581.27 to be
                                                                                                                          recoverable
      Provision for bad debt on a collective basis    209,567,199.87                0.00           0.00 209,567,199.87
                                                                                                                       Expected
      Other receivables of each company within
                                               209,567,199.87                       0.00           0.00 209,567,199.87 to be
      the scope of combination
                                                                                                                       recoverable
      Total                                           301,914,781.14                0.00           0.00 301,914,781.14




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As at 31 December 2020, provision for bad debts at step 2:


                                                                     Expected credit
                                                                                       Provision for
Type                                             Book balance         losses rate over                    Carrying value Reason
                                                                                          bad debts
                                                                     the lifetime (%)
Provision for bad debt on an individual basis                 0.00               0.00             0.00              0.00
Provision for bad debt on a collective basis      7,044,706.50                 30.99 2,183,283.55           4,861,422.95
Receivable deposits and deposits and rental
                                                  1,452,703.18                 41.56        603,754.83        848,948.35
fees
 Other receivables                               5,592,003.32                 28.25 1,579,528.72           4,012,474.60
Total                                             7,044,706.50                 30.99 2,183,283.55           4,861,422.95


As at 31 December 2020, provision for bad debts at step 3:


                                                                     Expected credit
                                                                                         Provision for
Type                                              Book balance        losses rate over                     Carrying value Reason
                                                                                            bad debts
                                                                     the lifetime (%)
Provision for bad debt on an individual basis    18,982,036.71                100.00 18,982,036.71                  0.00
                                                                                                                         Not
                                                                                                                         expected
Treasury bonds and Margin                        18,982,036.71                100.00 18,982,036.71                  0.00
                                                                                                                         to be
                                                                                                                         recoverable
Provision for bad debt on a collective basis                  0.00               0.00             0.00              0.00
Total                                            18,982,036.71                100.00 18,982,036.71                  0.00


Provision for bad debts made, recovered or reversed during the Period
                                                                                                              Unit: Yuan Currency: RMB
                                                    Step 1                         Step 2                      Step 3
                                                                 Expected credit losses       Expected credit losses
                                           Expected credit
Provision for bad debts                                               over the lifetime            over the lifetime              Total
                                            losses over the
                                                                  (without impairment             (with impairment
                                           next 12 months
                                                                             of credit)                   of credit)
Balance at the Beginning of the Period                0.00                 2,183,283.55              18,982,036.71      21,165,320.26
Balance at the Beginning of the Period
transferred for the Period
-- Transferred to step 2                              0.00                                                                         0.00
-- Transferred to step 3                              0.00                  -165,600.00                   165,600.00               0.00
-- Reversed in step 2                                 0.00                                                                         0.00
-- Reversed in step 1                                 0.00                                                                        0.00
Provisions made for the Period                        0.00                  -639,498.32                                    -639,498.32
Reversals for the Period                              0.00                                               1,013,650.67      1,013,650.67
Write-o for the Period                                0.00                                                                         0.00
Settlement for the Period                             0.00                           0.00                 165,600.00        165,600.00
Other changes                                         0.00                           0.00                        0.00              0.00
Balance at the End of the Period                      0.00                 1,378,185.23              17,968,386.04      19,346,571.27


Descriptions of the significant changes in the gross carrying amount of other receivables for which the changes in loss
allowance occur for the current period:
□ Applicable √ N/A


                                                                                                                                    285
      Provision for bad debts in the current period and the basis for assessing whether the credit risk of
      nancial instruments has increased signicantly:
      □ Applicable √ N/A

(4). Other receivables with ve largest amount by creditors at the End of the Period
     √ Applicable □ N/A
                                                                                                                     Unit: Yuan Currency: RMB
                                                                                                                  Proportion        Balance of
                                                                           Balance at                           to total other    provision for
      Name of unit                     Nature of receivables           the End of the           Ageing         receivables at      bad debts at
                                                                              Period                          the End of the     the End of the
                                                                                                                  Period (%)            Period
                                       Other receivables of each
      Shenzhen Fenglei Electric
                                       company within                 129,956,104.29          1-2 years                38.05
      Power Investment Co., Ltd.
                                        the scope of combination
                                       Other receivables of each
      Joincare Haibin
                                       company within                 111,500,000.25      Within 1 year                32.65
      Pharmaceutical Co., Ltd.
                                        the scope of combination
                                       Other receivables of each
      Topsino Industries Limited       company within                  36,954,169.56          1-2 years                10.82
                                        the scope of combination
      Shanghai Yunfeng Xinchuang
      Capital Management Center Capital reduction                      24,078,925.22          1-2 years                  7.05
      (L.P.)
      Huaxia Securities Co., Ltd       National debt and Margin        17,968,386.04 Above 5 years                       5.26 17,968,386.04
      Total                            /                              320,457,585.36                    /              93.83 17,968,386.04


(5). Other receivables derecognised due to the transfer of nancial assets
     □ Applicable √ N/A

(6). Assets and liabilities generated by the transfer of other receivables and continuing
     involvement therein
     □ Applicable √ N/A

      Other descriptions:
      □ Applicable √ N/A


 4. Long-term equity investments
      √ Applicable □ N/A
                                                                                                                     Unit: Yuan Currency: RMB
                                   Balance at the End of the Period                        Balance at the Beginning of the Period
      Item                                Provision for                                                     Provision for
                             Book balance                      Carrying value           Book balance                             Carrying value
                                           impairment                                                        impairment
      Investments in
                        3,453,138,312.11 7,010,047.91 3,446,128,264.20 3,193,969,921.11                     7,010,047.91     3,186,959,873.20
      subsidiaries
      Investments in
      associates and        84,810,888.09             0.00      84,810,888.09           86,816,710.23                0.00        86,816,710.23
      joint ventures
      Total             3,537,949,200.20 7,010,047.91 3,530,939,152.29 3,280,786,631.34                     7,010,047.91     3,273,776,583.43




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                                                                                                                                                           2021


(1). Investments in subsidiaries
     √ Applicable □ N/A
                                                                                                                                          Unit: Yuan Currency: RMB
                                                                                                                                     Provision for       Balance of
                                                       Balance at            Increase            Decrease             Balance at
                                                                                                                                      impairment       provision for
     Investee                                      the Beginning           during the           during the            the End of
                                                                                                                                           for the impairment at the
                                                      of the Year              Period               Period            the Period
                                                                                                                                           Period End of the Period
     Livzon                                    608,741,654.08                     0.00                  0.00      608,741,654.08               0.00                     0.00
     Haibin Pharma                             783,054,186.38                     0.00                  0.00      783,054,186.38               0.00                     0.00
     Joincare Daily-Use                            24,116,498.56                  0.00                  0.00       24,116,498.56               0.00         1,610,047.91
     Topsino                                   813,552,689.31                     0.00                  0.00      813,552,689.31               0.00                     0.00
     Taitai Genomics                               37,500,000.00                  0.00                  0.00       37,500,000.00               0.00                     0.00
     Taitai Pharmaceutical                     105,939,709.72                     0.00                  0.00      105,939,709.72               0.00                     0.00
     Shenzhen Hiyeah                           170,100,000.00                     0.00                  0.00      170,100,000.00               0.00         5,400,000.00
     Joincare Biology                              59,868,800.00                  0.00 59,868,800.00                          0.00             0.00                     0.00
     Fenglei Electric Power                    100,763,433.06                     0.00                  0.00      100,763,433.06               0.00                     0.00
     Jiaozuo Joincare                          375,000,000.00                     0.00                  0.00      375,000,000.00               0.00                     0.00
     Shanghai Frontier                             32,500,000.00                  0.00                  0.00       32,500,000.00               0.00                     0.00
     Taitai Biological                              4,832,950.00                  0.00                  0.00        4,832,950.00               0.00                     0.00
     Joincare Haibin                               75,000,000.00      25,000,000.00                     0.00      100,000,000.00               0.00                     0.00
     Joincare (Guangdong) Special
                                                    3,000,000.00                  0.00                  0.00        3,000,000.00               0.00                     0.00
     medicine Food Co., Ltd.
     Zhuhai Livzon Biotechnology
                                                               0.00 294,037,191.00                      0.00      294,037,191.00               0.00                     0.00
     Co., Ltd.*
     Total                                  3,193,969,921.11 319,037,191.00 59,868,800.00 3,453,138,312.11                                     0.00         7,010,047.91


     Note 1: Zhuhai Jiankangyuan completed the industrial and commercial deregistration on 8 September , 2021;
     Note 2: In April 2021, the Company and its subsidiary Haibin Pharma completed the capital increase in Joincare Haibin
             Pharmaceutical Co., Ltd.
     Note 3: Zhuhai Livzon Biotechnology Co., Ltd. is a subsidiary within the consolidation scope of Livzon Group. Which originally
             held 100% indirectly by Livzon Group. In this period, due to the restructuring of the equity structure of the holding
             subsidiary of Livzon Group, Livzon Group held 55.13% of its equity, and the Company held 35.75% of its equity.

(2). Investments in associates
     √ Applicable □ N/A
                                                                                                                                          Unit: Yuan Currency: RMB
                                                                                     Change during the Period
                                                                                                                                                                   Balance of
                                                                                          Adjustment                 Cash
                                   Balance at the                             Investment                                                              Balance    provision for
                                                            Decreased                         in other  Other    dividend Provision
     Investee                         Beginning Increased                       prot and                                                         at the End of    impairment
                                                               invest                             com equity      or prot     for Im Others
                                      of the Year investmen                loss under the                                                           the Period      at the End
                                                                ment                      -prehensive changes distribution -pairment
                                                                           equity method                                                                         of the Period
                                                                                               income            declared
     Associates
     Ningbo Ningrong Biological
                                   28,301,318.36        0.00        0.00    -837,219.65          0.00      0.00        0.00      0.00   0.00    27,464,098.71            0.00
     Medicine Co., Ltd.
     Feellife Health Inc.          10,176,384.11        0.00        0.00     513,198.04          0.00      0.00        0.00      0.00   0.00    10,689,582.15            0.00
     Novastage Pharmaceuticals
                                   19,561,050.64        0.00        0.00   -1,480,167.43         0.00      0.00        0.00      0.00   0.00    18,080,883.21            0.00
     (Shenzhen), Ltd.
     Jiangsu Baining Yingchuang
                                   28,777,957.12        0.00        0.00    -201,633.10          0.00      0.00        0.00      0.00   0.00    28,576,324.02            0.00
     Medical Technology Co., Ltd
     Total                         86,816,710.23        0.00        0.00   -2,005,822.14         0.00      0.00        0.00      0.00   0.00    84,810,888.09            0.00



                                                                                                                                                                         287
 5. Operating income and operating cost
      Operating income and operating cost
      √ Applicable □ N/A
                                                                                                       Unit: Yuan Currency: RMB
                                                            For the Period                           For the Previous Period
      Item
                                                           Cost                 Income               Cost              Income
      Principal activities                     1,997,946,818.28      1,345,944,915.00     1,415,902,371.85     915,525,922.84
      Other activities                            23,227,007.34        10,880,121.11        17,173,139.38         5,717,311.02
      Total                                    2,021,173,825.62      1,356,825,036.11     1,433,075,511.23     921,243,233.86


    Other descriptions:
    Descriptions of operating income
 ① Operating income and operating cost presented by product types


                                                             For the Period                          For the Previous Period
      Item
                                                            Cost                Income             Income                   Cost
      Health care products                       115,187,552.33        73,483,571.30       138,445,501.80       89,635,887.75
      Chemical drug preparation products       1,844,258,573.30      1,249,873,341.86     1,237,805,648.80     801,249,508.12
      Traditional Chinese drug preparation        38,481,963.54        22,519,595.22        38,914,059.05       23,894,996.93
      Others                                           18,729.10              68,406.62        737,162.20          745,530.04
      Total                                    1,997,946,818.28      1,345,944,915.00     1,415,902,371.85     915,525,922.84


 ② Operating income and operating cost presented by major operating regions


                                                             For the Period                       For the Previous Period
      Item
                                                            Cost                Income               Cost              Income
      Domestic                                 1,997,946,818.28      1,345,944,915.00     1,415,902,371.85     915,525,922.84
      Total                                    1,997,946,818.28      1,345,944,915.00     1,415,902,371.85     915,525,922.84


 ③ Operating income and operating cost presented by time of income recognition


                                                             For the Period                       For the Previous Period
      Item
                                                         Income                   Cost             Income                   Cost
      Commodities (transferred at a point in
                                               1,997,946,818.28      1,345,944,915.00     1,415,902,371.85     915,525,922.84
      time)
      Total                                    1,997,946,818.28      1,345,944,915.00     1,415,902,371.85     915,525,922.84


 (3) Descriptions of other activities


                                                             For the Period                       For the Previous Period
      Item
                                                         Income                   Cost             Income                   Cost
      Processing fee                                1,403,169.59         1,712,962.53                 0.00                  0.00
      Rental fees                                 13,104,696.50          1,989,089.05       14,722,066.99         3,333,402.42
      Others                                        8,719,141.25         7,178,069.53         2,451,072.39        2,383,908.60
      Total                                       23,227,007.34         10,880,121.11       17,173,139.38         5,717,311.02




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                                                                                                                                                         2021


 6. Investment income
    √ Applicable □ N/A
                                                                                                                                           Unit: Yuan Currency: RMB
     Item                                                                                                 For the Period                    For the Previous Period
     Long-term equity investments income under cost method                                            1,351,395,397.50                             545,238,761.01
     Long-term equity investments income under equity method                                             -2,005,822.14                              -1,887,802.59
     Investment income from disposal of long-term equity investments                                     -59,868,800.00                              -2,807,961.97
     Dividend income from other equity instrument investments                                               4,175,569.86                              3,836,778.08
     Investment income from disposal of nancial assets held for trading                                         50,958.36                                      0.00
     Total                                                                                            1,293,747,303.58                             544,379,774.53


XVI Supporting Information

 1. Statement of non-recurring profit or loss
    √ Applicable □ N/A
                                                                                                                                           Unit: Yuan Currency: RMB
     Item                                                                                                                                                    Amount
     Prot or loss from disposal of non-current assets                                                                                                  14,492,047.24
     Return, exemption and discharge of taxes resulting from approving ultra vires, or without formal approval or incidentally incurred                         0.00
     Government grants as included in the current prot or loss, however, except for those which are closely related to the normal
     business of an enterprise, comply with the policies of the State and are continuously entitled with specic amount or quantity                    245,335,140.69
     according to certain standards
     Funds occupation fees charged from non-nancial enterprises                                                                                                 0.00
     Gains resulting from the investment cost of the enterprise for the purpose of acquisition of the subsidiaries, joint operation and joint
                                                                                                                                                                0.00
     ventures is lower than the fair value of net identiable assets of the investee as entitled at the time of receipt of the investment
     Prot or loss from exchange of non-monetary assets                                                                                                          0.00
     Prot or loss from investment or management of assets by the others                                                                                         0.00
     Provision for impairment of assets accrued due to force majeure factors, such as natural disasters                                                         0.00
     Prot or loss from debts restructuring                                                                                                                      0.00
     Enterprise restructuring fees, such as the expenses for employees’settlement and the integration fees                                                     0.00
     Prot or loss exceeding the fair value and generated from the transaction of which the transaction price is obviously unfair                                0.00
     Net prot or loss over the current period of the subsidiaries as a result of business combination under common control from the
                                                                                                                                                                0.00
     beginning of the year to the date of consolidation
     Prot or loss from contingent issues irrelevant to the Company's normal business                                                                            0.00
     Except for the ecient hedging related to the Company's normal business, prot or loss from changes in fair value as generated
     from nancial assets and nancial liabilities held for trading and gains from investment as a result of the disposal of nancial assets                8,110,644.25
     and nancial liabilities held for trading and debt investments
     Reversals of provision for impairment of accounts receivable with individual impairment test                                                       1,013,650.67
     Prot or loss from entrusted loans                                                                                                                          0.00
     Gains or losses from changes in the fair values of investment properties that are subsequently measured using the fair value model                         0.00
     Impact of a one-time adjustment on current prot and loss according to the requirements of tax and accounting laws and regulations                          0.00
     Custody fees of entrusted operation                                                                                                                         0.00
     Other non-operating income and expenses besides the above items                                                                                   -30,737,442.83
     Other items that conform to the denition of non-recurring prot or loss                                                                                     0.00
     Less: Eect of income tax                                                                                                                          39,580,260.30
     Eect of minority equity                                                                                                                           95,131,719.24
     Total                                                                                                                                            103,502,060.48




                                                                                                                                                                 289
      Provide explanations for classifying non-recurring profit and loss items defined in the Explanatory Announcement No. 1 for
      Public Company Information Disclosures –Non-recurring Prots and Losses, and for classifying non-recurring prot and loss
      items listed in the Explanatory Announcement No. 1 for Public Company Information Disclosures –Non-recurring Prots and
      Lossesas recurring prot and loss item.
      □ Applicable √ N/A


 2. Rate of return on net assets and earnings per share
      √ Applicable □ N/A


                                                                               Weighted average           Earnings per share
      Prot for the Reporting Period
                                                                            return on equity (%)    Basic EPS       Diluted EPS
      Net loss attributable to the Company's ordinary shareholders                        11.50        0.6864            0.6858
      Net prot attributable to the parent company's shareholders,
                                                                                          10.60        0.6329            0.6324
      excluding non-recurring prot or loss


 3. Differences in accounting data under domestic and foreign accounting standards
      □ Applicable √ N/A


 4. Others
      □ Applicable √ N/A




                                                                                      Chairman: Zhu Baoguo
                                                                     Date of Submission Approved by the Board: 29 March 2022



      Revised information
      □ Applicable √ N/A




290