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健康元:健康元药业集团股份有限公司2022年年度报告(英文版)2023-04-11  

                        Joincare Pharmaceutical Group               Annual Report 2022



Stock Code: 600380                  Stock Short Name: 健康元




JOINCARE PHARMACEUTICAL GROUP INDUSTRY CO., LTD.
                2022 Annual Report




                                1
Joincare Pharmaceutical Group                                                    Annual Report 2022


                                        Important Notice



I. The Board of Directors (the “Board”), the Board of Supervisors and directors, supervisors
and senior management of the Company hereby warrant the truthfulness, accuracy and
completeness of the contents of this annual report (the “Report”), and that there are no false
representations, misleading statements or material omissions contained in the Report, and
severally and jointly accept legal responsibility.


II. All directors of the Company attended the Board meeting.


III. Grant Thornton (Special General Partnership) issued a standard unqualified audit report
for the Company.


IV. Mr. Zhu Baoguo (朱保国), the person-in-charge of the Company, and Mr. Qiu Qingfeng
(邱庆丰), the person-in-charge of accounting work and the person-in-charge of the accounting
department (the head of the accounting department) declare that they hereby warrant the
truthfulness, accuracy and completeness of the financial statements contained in the Report.


V. Profit distribution plan or plan for conversion of capital reserve to share capital approved
by the Board resolution during the Reporting Period
Based on the audit conducted by Grant Thornton (Special General Partnership), in 2022, the Parent
Company generated net profit of RMB849,731,957.95, 10% of which was contributed to the
statutory surplus reserve, namely RMB84,973,195.80, the remainder of which, together with
undistributed profits for the last year of RMB1,400,174,178.18 and gain on disposal of other equity
investments of RMB80,749,859.60, subtracting cash dividends for the last year of
RMB277,557,631.65, is the profits available for distribution to shareholders for the year of
RMB1,968,125,168.28. The Company plans to distribute cash dividends for the fiscal year 2022,
based on the total number of shares for dividend distribution, which is defined by the total shares of
Company, minus the shares in the Share Repurchase Account, on the equity registration date
designated by the annual profit distribution plan. The Company plans to distribute cash dividend of
RMB1.80 (tax inclusive) for every 10 shares of to all shareholders of the Company, and the
remaining undistributed profits will be carried forward to the following year.


VI. Risk declaration for the forward-looking statements
√Applicable □N/A
The Report contains forward-looking statements which involve the future plans, development
strategies, etc. of the Company, yet do not constitute substantive undertakings of the Company to
investors. Investors should exercise caution prior to making investment decisions.


VII. Whether there is non-operating use of funds by the controlling shareholder and their
related parties
No


VIII. Whether there is a violation of the prescribed decision-making procedures to provide
external guarantees

                                                  2
Joincare Pharmaceutical Group                                                  Annual Report 2022


No


IX. Whether more than half of directors cannot warrant the truthfulness, accuracy and
completeness of the Report disclosed by the Company
No


X. Significant risk warnings
There is no exceptionally significant risk that will have a material impact on the production and
operation of the Company during the Reporting Period. In this Report, the Company has elaborated
on the risks and countermeasures that the Company may face in the course of production and
operation, including industry policy risk, market risk, risk of safety and environmental protection,
risk in price and supply of raw materials and R&D risk. For more information, please refer to
“Potential risks” part in Chapter 3 Management Discussion and Analysis.


XI. Others
□Applicable √N/A




                                                 3
Joincare Pharmaceutical Group                                                                                 Annual Report 2022



                                                     Table of Contents


Important Notice.........................................................................................................................2

Chairman's Statement .................................................................................................................5

Financial Highlights .................................................................................................................10

Chapter 1 Definitions ...............................................................................................................12

Chapter 2 Company Profile and Major Financial Indicators ....................................................14

Chapter 3 Management Discussion and Analysis ....................................................................19

Chapter 4 Corporate Governance .............................................................................................78

Chapter 5 Environmental and Social Responsibility ................................................................99

Chapter 6 Major Events .........................................................................................................123

Chapter 7 Changes in Equity and Shareholders .....................................................................141

Chapter 8 Information on Preferred Shares ............................................................................148

Chapter 9 Information on Bonds ............................................................................................149

Chapter 10 Financial Statements ............................................................................................150




                          The Financial Statements signed and sealed by the person-in-charge of
                          the Company, the person-in-charge of the Company's accounting work
                          and the person-in-charge of the accounting department (the head of the
                          accounting department)
   List of documents      The original document of the auditors’ report sealed by the accounting
 available for inspection firm and signed and sealed by the certified public accountants
                          The original copies of all documents and announcements of the
                          Company which have been disclosed to the public on the website
                          designated by CSRC (China Securities Regulatory Commission) during
                          the Reporting Period




                                                                    4
Joincare Pharmaceutical Group                                                     Annual Report 2022



                                  Chairman's Statement

Dear shareholders,

2022 was a year of both carrying forward and breaking new ground for the implementation of the
“14th Five-Year” Plan and a crucial year for deeply promoting the “Healthy China’ initiative, and
deepening the reform of the medical and healthcare systems. During this year, the pharmaceutical
industry underwent significant structural adjustments and steadily entered the “new normal” of
transformation and upgrading with more opportunities than challenges. Under the guidance of the
national “14th Five-Year” Plan, a number of major policies and guidelines related to the
pharmaceutical industry have been released and the theme of high-quality development has become
the focus of the new era.

2022 was the 30th anniversary of the establishment of Joincare. During the 30 years with significant
changes in the industry, the Group adhered to the mission of “For the health, For the future” and the
vision to “Diligently make high-quality and innovative drugs”, focused on the high-quality
development of the principal pharmaceutical business, maintained its strategic focuses, and
tactically demonstrated its resilience and potential. Based on the development blueprint outlined in
the Report to the 20th National Congress of the CPC, the Group achieved effective qualitative
improvement and reasonable quantitative growth in expediting product innovation, achieving
technical breakthroughs, expanding industrial chains, enhancing the comprehensive
competitiveness, and accelerating the pace of internationalization. With the fortitudinous and
steadfast efforts of all staff, the Group recorded sustained and steady performance growth and
successfully achieved its annual business goals.

In 2022, the Group realized total revenues of RMB17,143 million, representing a year-on-year
increase of approximately 7.79%; realized a net profit attributable to shareholders of listed
companies of RMB1,503 million, representing a year-on-year increase of approximately 13.10%;
and realized a net profit attributable to shareholders of listed companies after deduction of the
extraordinary gains and losses of RMB1,419 million, representing a year-on-year increase of
approximately RMB194 million or 15.84%.

We maintained steady performance growth and strived to create higher returns for our
shareholders. Based on the operating results and overall financial position of the Group in 2022,
the Board of Directors proposed that we continue to adopt a stable profit distribution scheme in
2022. Specifically, a cash dividend of RMB1.80 (tax inclusive) for every 10 shares will be
distributed to all shareholders of the Company, based on the total number of shares (excluding the
number of shares repurchased but not cancelled by the Company) on the equity registration date
designated by the annual profit distribution plan for 2022. No bonus shares will be distributed and
no conversion of capital reserve into share capital will be carried out. The profit distribution scheme
for 2022 is yet to be reviewed and approved at the Company’s 2022 Annual General Meeting.

In 2022, the Group deeply implemented the dual-drive strategy of developing platforms of
both innovative medicines and high-barrier complex formulations, focused on unmet clinical
needs and constantly created and developed new drivers and new advantages. In terms of
R&D innovation, the Group continuously increased R&D expenditures while constantly refining

                                                  5
Joincare Pharmaceutical Group                                                    Annual Report 2022


differentiated innovation R&D strategies. It combined “long-term” and “short-term” plans on
strategic plannings and pipeline deployments and concentrated on the construction of R&D systems
covering the full lifecycle of drugs development and production.

We continued to increase our R&D expenditures and boosted efforts in the construction of
innovative R&D technology platforms for high-barrier complex formulations, including inhalation
formulation, antibody, and sustained-release microspheres for injections. We have achieved
remarkable results. In 2022, the R&D of many innovative medicine products and high-barrier
complex formulations in the Group’s pipeline made significant progress with 6 products approved
for launching, 5 products applied for production and 5 products approved for clinical trials.

The birth of each new drug or the initiation of each new therapy represents a process of perception
to diseases. In October 2022, Tobramycin Inhalation Solution (妥布霉素吸入溶液), a blockbuster
product of the Group, was approved for launching. It is the first inhalation drug for bronchiectasis
in the world as well as the first nebulizer inhalation antibiotic launched in China, marking that the
situation of “no drugs available” faced by bronchiectasis patients in China will be significantly
relieved. Meanwhile, it further validates our strategic correctness and the market leader advantages
in the inhalation formulation products market.

While adhering to strengthening independent innovation, the Group also pays close attention to
domestic and overseas cutting-edge technologies and opportunities. In 2022, Joincare and its
subsidiary, Livzon Group, jointly established an industrial investment entity and contributed a total
of RMB1 billion to strategically invest in high-quality healthcare industry projects, demonstrating
the strength and determination of the Group in boosting industrial innovation through “bringing in
investments”, establishing diversified platforms for incubating and introducing R&D and
innovation projects, rapidly diversifying core pipeline products of the Company and further
bolstering the sustained profitability of the Group.

In terms of business scope innovation, we continued to use our existing strength as a “springboard”
for new businesses, expanding our business territory at a steady pace. In 2022, the Recombinant
SARS-CoV-2 Fusion Protein (CHO Cell) Vaccine “Likang V-01”, jointly developed by the Institute
of Biophysics of the Chinese Academy of Sciences and Joincare, was successfully developed and
approved to be included for heterologous booster vaccination.

Our success in R&D of Likang V-01 relies on our ability of R&D transform R&D achievements in
the whole chain from clinical research and production to approval, marketing and terminal
promotion; and the launch of Likang V01 represents significant breakthroughs in both the
construction of the recombinant protein vaccine platform and the commercialization capability in
vaccine market niche.

In the end of 2022, we adopted new measures in the expansion of the business scope. Relying on
the strategic advantages in “APIs-formulations vertical integration” and the leading position in core
pet drugs’ APIs of the two listed companies, Joincare and Livzon Group, we integrated our
advantageous resources in the R&D, production, brand promotion, online and offline marketing
through all channels in the pet drugs sector, coordinated the operation of animal health care products
and further boosted the layout on animal health care formulations.



                                                  6
Joincare Pharmaceutical Group                                                     Annual Report 2022


In terms of business model innovation, in 2022, the Group continued to strengthen and upgrade
the “patient-centered” digital marketing ecosystem, adopted new digital marketing models for
respiratory drugs, namely “to empower all links including education, screening, diagnosis, treatment,
and medication monitoring, form a closed-loop consisting of doctors, hospitals, patients and
pharmaceutical companies, and explore the external huge market of chronic disease management
with owned traffic, so as to realize real-time interaction between consumers and brands” to expand
to gastroenterological, psychiatric and other advantageous sectors of the Group. In 2022, healthcare
products & OTC segment of the Group successfully promoted the iteration and upgrading of “Taita”
(太太) and other core classical brands through omni-channel strategy. On one hand, it continuously
promoted the reform of the offline team structure, upgraded the distribution channel, integrated the
key chain stores and empowered the Company with resources; on the other hand, it continued to
improve online self-operated channels such as platforms of Tmall, Jingdong (JD), Douyin e-
commerce and WeChat Mall, Leveraging on online quality content platforms, it conveyed the
scientifically based healthcare concept, accurately reached target users and empowered the
revitalization of time-honored brands.

We always adhered to the strategy on the coordinated development of industry and capital
operation. With our top-notch intuition, courage and industry standard, while leveraging on
the opportunities in the capital market, Joincare has maintained the fast-moving edge in the
integration of industry and capital market for three decades.

In September 2022, the Global Depository Receipts (GDRs) of Joincare were successfully listed on
the SIX Stock Exchange, making us the first domestic bio-pharmaceutical enterprise with GDRs
issued and successfully listed in Switzerland. As a result, the two listed companies under the Group
jointly set a precedent for being listed on, in total, four exchanges in China, Hong Kong and
Switzerland. The Group has been paying close attention to policies and opportunities for the
innovative development of the capital market and actively serving the strategic development and
business layout of enterprises through the capital market. The successful issuance of GDRs in
Switzerland represents a key milestone in the internationalization strategy of Joincare, facilitates the
Group’s internalization strategy in expanding businesses overseas, and allows the Company to
develop an international horizon, pattern and operating logic to improve international recognition,
so as to enhance the overall profitability and comprehensive competitiveness of the Company.

We always actively undertake social responsibilities and integrate the ESG concept into all
links of the strategy and operation of the Group with practical actions. We proactively focus
on the internal regulatory environment and external policy guidance and practice the CSR strategy
and social welfare initiatives adapted to our current business situation in combination with China’s
14th Five-Year Plan and the local government’s development plan.

As a leader in domestic market niche of inhalation formulations, we shoulder the undertakings of
pharmaceutical enterprises to serve the country and people. Following the listing of three inhalation
formulation products in the fifth-round national volume-based procurement, including 雾舒, 舒
坦琳,丽雾安 and 特瑞通, a new product, successfully won the bidding in the seventh round of
national volume-based procurement in July 2022. We have been implementing the concept of
inclusive health through academic works, public welfare actions and the promotion of scientific
popularization to increasingly enhance the awareness on the diagnosis, treatment and management


                                                   7
Joincare Pharmaceutical Group                                                    Annual Report 2022


of chronic diseases and improve the accessibility of drugs. As of the end of 2022, “Respiratory
Experts' Views” ( 呼 吸 专 家 说 ), a public welfare patient education platform in the domestic
respiratory diseases sector under the Group, which is the first of its kind in the industry, had joined
hands with thousands of doctors in popularizing the scientific concept on the prevention of chronic
respiratory diseases among millions of followers. It focused on Chronic obstructive pulmonary
disease (COPD), bronchiectasis and other respiratory diseases with high morbidity but low
awareness and rate of standardized treatment, supporting the “Healthy China 2030” with practical
actions. In 2022, the segment of inhalation formulations of Joincare realized revenues of RMB1.174
billion, representing a year-on-year increase of 103.37%. Such figures mean that an increasing
number of Chinese people obtain high-quality domestic new drugs at a more affordable price.

In 2022, the Recombinant SARS-CoV-2 Fusion Protein (CHO Cell) Vaccine “Likang V-01” under
the Group was included into the preferred combinations under the Implementation Plan for
Vaccination of Second Booster Dose of COVID-19 Vaccines. During the fight against the COVID-
19 pandemic, the Group contributed the strength of pharmaceutical enterprises in building
immunologic barriers for people with underlying diseases, the elderly, people exposed to high risks
and other key groups through vaccines with excellent protection and high safety. In addition, the
Tocilizumab Solution for Injection (Atvtia) (托珠单抗注射液(安维泰)) was approved for market
launch in January 2023 and listed in the Diagnosis and Treatment Protocol for COVID-19 (Trial
Version 10) and the Diagnosis and Treatment Protocol for Severe COVID-19 Cases (Trial Version
4), effectively relieving the shortage of drugs for severe COVID-19 patients.

The Group has actively responded to national policies and calls for years. In combination with its
own industrial advantages, the Group jointly launched the “Access to Public Welfare for Chronic
Diseases Prevention and Treatment (普惠慢病防治公益项目)”program, which currently covers 8
provinces and 1 autonomous region. It brought drugs and other materials for patients with chronic
diseases in remote areas, alleviated their medical burdens and further improved the accessibility of
drugs. In 2022, the Group’s public welfare donations amounted to approximately RMB12.117
million.

2023 is the first year for implementing the spirit of the 20th National Congress of the CPC. Based
on the new situation and new stage of the pharmaceutical industry, the Group will anchor in high-
quality development, conduct in-depth layout with the focus on the two strategic orientations of
innovation and internationalization, and review current opportunities and challenges while
continuing to balance aspiration with practicality. Firstly, we will stick to and speed up in R&D
innovation and continuously launch products with high quality and accurate efficacy. Secondly, we
will boost technological and management innovation and vigorously advance the progress of
internationalization. Thirdly, we will bravely try new technologies and models, and implement the
digital and intelligent transformation in all links of industrial chains from R&D, production and
sales to management, so as to improve the operational efficiency and adapt to the new trends of the
pharmaceutical industry and market. The Group will continue to deeply penetrate into the markets
of innovative drugs and high-barrier complex formulations, keep an acute insight on market changes,
break conventional thinking and path dependence, continuously consolidate the industrial position
of the Group in all segments and speed up in promoting the high-quality development of industries.

In 1992, Joincare embarked on its journey with a strong sense of purpose and determination. Over


                                                  8
Joincare Pharmaceutical Group                                                     Annual Report 2022


the past three decades, it has overcome many challenges and navigated through significant changes
in the industry. This top integrated pharmaceutical enterprise with revenues of RMB17.1 billion,
was not a surf boat but became an aircraft carrier in the domestic field of innovation. It will not only
ride through the ups and downs of the industry firmly and confidently, but also attract, match and
carry more and more like-minded partners to sail, at full speed, towards the new era for the
pharmaceutical industry with a bright future.

On behalf of the Board of the Company, I would like to take this opportunity to express my sincere
gratitude to all Shareholders, all staff of the Group and business partners for their long-lasting care,
companion and support.




                                                                               Chairman: Zhu Baoguo

                                                                                          7 April 2023




                                                   9
Joincare Pharmaceutical Group                          Annual Report 2022



                                Financial Highlights




                                         10
Joincare Pharmaceutical Group                          Annual Report 2022



                                Financial Highlights




                                         11
Joincare Pharmaceutical Group                                                      Annual Report 2022



                                  Chapter 1 Definitions

I.    Definitions

In this Report, unless the context otherwise requires, the following expressions shall have the
following meanings:

 Definitions of common terms
 CSRC                              Refers to   China Securities Regulatory Commission
 SSE                               Refers to   Shanghai Stock Exchange
 SZSE                              Refers to   Shenzhen Stock Exchange
 Baiyeyuan or the Controlling                  Shenzhen Baiyeyuan Investment Co., Ltd. * (深圳市百业
                                   Refers to
 Shareholder                                   源投资有限公司)
 Company, the Company, Group or                Joincare Pharmaceutical Group Industry Co., Ltd.* (健康
                                   Refers to
 the Group                                     元药业集团股份有限公司)
 GMP                               Refers to   Good Manufacturing Practice
 GSP                               Refers to   Good Supply Practice
                                               The certification of the products by European Union,
                                               indicating that the product has complied the safety
                                               requirements specified in the European Directives. The
 CE                                Refers to   access condition for a product to enter the EU market is
                                               that the product has undergone the appropriate conformity
                                               assessment procedures and the declaration of conformity
                                               of a manufacturer, with attachment of CE mark
                                               Certificate of Suitability to Monograph of European
 CEP                               Refers to
                                               Pharmacopoeia
 BE                                Refers to   Bioequivalence
 BLA                               Refers to   Biologics License Application
 IND                               Refers to   Investigational New Drug Application
 R&D                               Refers to   Research and Development
 TCM                               Refers to   Traditional Chinese Medicine
 NHSA                              Refers to   National Health Security Administration
 NMPA                              Refers to   National Medical Products Administration
                                               Livzon Pharmaceutical Group Inc.* (丽珠医药集团股份
 Livzon Group                      Refers to
                                               有限公司)
                                               Shenzhen Haibin Pharmaceutical Co., Ltd.* (深圳市海滨
 Haibin Pharma                     Refers to
                                               制药有限公司)
                                               Joincare Haibin Pharmaceutical Co., Ltd.* (健康元海滨药
 Joincare Haibin                   Refers to
                                               业有限公司)
                                               Xinxiang Haibin Pharmaceutical Co., Ltd. * (新乡海滨药
 Xinxiang Haibin                   Refers to
                                               业有限公司)
                                               Shenzhen Taitai Pharmaceutical Co., Ltd. * (深圳太太药
 Taitai Pharmaceutical             Refers to
                                               业有限公司)
                                               Shenzhen Taitai Genomics Inc. Co., Ltd. * (深圳太太基因
 Taitai Genomics                   Refers to
                                               工程有限公司)
                                               Shenzhen Taitai Biotechnology Co., Ltd. *(深圳太太生物
 Taitai Biotechnology              Refers to
                                               科技有限公司)
                                               Henan Province Joincare Biopharmaceutical Research
 Joincare Biopharmaceutical
                                   Refers to   Institute Co., Ltd. *(河南省健康元生物医药研究院有
 Research Institute
                                               限公司)
                                               Jiaozuo Joincare Bio Technological Co., Ltd.*(焦作健
 Jiaozuo Joincare                  Refers to
                                               康元生物制品有限公司)
                                               Joincare Daily-Use & Health Care Co., Ltd. * (健康元日
 Joincare Daily-Use                Refers to
                                               用保健品有限公司)
 Topsino                           Refers to   Topsino Industries Limited * (天诚实业有限公司)
                                               Shenzhen Fenglei Electric Power Investment Co., Ltd. *
 Fenglei Electric Power            Refers to
                                               (深圳市风雷电力投资有限公司)
                                               Health Pharmaceutical (China) Co., Ltd. * (健康药业(中国)
 Health Pharmaceutical             Refers to
                                               有限公司)


                                                 12
Joincare Pharmaceutical Group                                                      Annual Report 2022


                                                 Shenzhen Hiyeah Industry Co., Ltd. * ( 深圳市喜悦实业
 Hiyeah Industry                     Refers to
                                                 有限公司)
                                                 Shanghai Frontier Health Pharmaceutical Technology Co.,
 Shanghai Frontier                   Refers to   Ltd. *(上海方予健康医药科技有限公司)
                                                 Joincare (Guangdong) Special Medicine Food Co., Ltd.
 Joincare Special Medicine Food      Refers to   *(健康元(广东)特医食品有限公司)
                                                 Livzon MABPharm Inc. * (珠海市丽珠单抗生物技术有
 Livzon MAB                          Refers to
                                                 限公司)
                                                 Zhuhai Livzon Diagnostics Inc. * ( 珠海丽珠试剂股份有
 Livzon Diagnostics                  Refers to
                                                 限公司)
                                                 Livzon Group Fuzhou Fuxing Pharmaceutical Co.,
 Fuzhou Fuxing                       Refers to   Ltd.*(丽珠集团福州福兴医药有限公司)
                                                 Livzon Group Xinbeijiang Pharmaceutical Manufacturing
 Livzon Xinbeijiang                  Refers to   Inc.*( 丽珠集团新北江制药股份有限公司)
                                                 Livzon Group (Ningxia) Pharmaceutical Manufacturing
 Ningxia Pharmaceutical              Refers to
                                                 Co., Ltd.* ( 丽珠集团 ( 宁夏) 制药有限公司)
                                                 Gutian Fuxing Pharmaceutical Co., Ltd. * ( 古田福兴医
 Gutian Fuxing                       Refers to
                                                 药有限公司)
                                                 Zhuhai     FTZ     Livzon     Hecheng      Pharmaceutical
 Livzon Hecheng                      Refers to   Manufacturing Co., Ltd. * ( 珠海保税区丽珠合成制药有
                                                 限公司)
                                                 Livzon Group Limin Pharmaceutical Manufacturing
 Livzon Limin                        Refers to   Factory *(丽珠集团利民制药厂)
                                                 Livzon Group Livzon Pharmaceutical Factory * (丽珠集
 Livzon Pharmaceutical Factory       Refers to
                                                 团丽珠制药厂)
                                                  Jiaozuo Livzon Hecheng Pharmaceutical Manufacturing
 Jiaozuo Hecheng                     Refers to
                                                  Co., Ltd.* ( 焦作丽珠合成制药有限公司)
                                                 Shanghai Livzon Pharmaceutical Manufacturing Co., Ltd.
 Shanghai Livzon                     Refers to   *( 上海丽珠制药有限公司)
                                                 Sichuan Guangda Pharmaceutical Manufacturing Co., Ltd.
 Sichuan Guangda                     Refers to   *( 四川光大制药有限公司)
                                                 Jiaozuo Jinguan Jiahua Electric Power Co., Ltd. *( 焦作金
 Jinguan Electric Power              Refers to
                                                 冠嘉华电力有限公司)
                                                 Tianjin Tongrentang Group Co., Ltd. * ( 天津同仁堂集团
 Tianjin Tongrentang                 Refers to
                                                 股份有限公司)
                                                 Zhuhai Sanmed Biotech Inc. * ( 珠海圣美生物诊断技术
 Sanmed Biotech                      Refers to
                                                 有限公司)
                                                 Zhuhai Livzon Biotechnology Co., Ltd.*( 珠海市丽珠生
 LivzonBio                           Refers to
                                                 物医药科技有限公司)
 Greenanew                           Refers to   Greenanew (Shanghai) Biotechnology Co., Ltd.
 COVID-19                            Refers to   A new coronavirus (SARS-CoV-2)
                                                 The outbreak of the disease caused by a new coronavirus
  COVID- 19 pandemic or pandemic     Refers to
                                                 called SARS-CoV-2
                                                 Ruihua Certied Public Accountants (Special General
 Ruihua Certied Public Accountants   Refers to
                                                 Partnership)
 Grant Thornton                      Refers to   Grant Thornton (Special General Partnership)
 Reporting Period                    Refers to   From 1 January 2022 to 31 December 2022
 End of the Reporting Period         Refers to   31 December 2022
 Currency or unit                    Refers to   RMB unless otherwise specied




                                                  13
Joincare Pharmaceutical Group                                                              Annual Report 2022




         Chapter 2 Company Profile and Major Financial Indicators
I. Company profile

Chinese name of the Company                       健康元药业集团股份有限公司
Abbreviation of the Chinese name                  健康元
English name of the Company                       Joincare Pharmaceutical Group Industry Co., Ltd.
Abbreviation of the English name                  Joincare
Legal representative of the Company               Zhu Baoguo(朱保国)


II. Contact persons and contact information

                 Board Secretary                                Representatives of Securities Aairs
Name             Zhao Fengguang ( 赵凤光 )                      Li Hongtao( 李洪涛 ) and Luo Xiao( 罗逍 )
                 Joincare Pharmaceutical Group Building, No.    Joincare Pharmaceutical Group Building, No. 17,
Address          17, Langshan Road, North District, Hi-tech     Langshan Road, North District, Hi-tech Zone,
                 Zone, Nanshan District, Shenzhen               Nanshan District, Shenzhen
Telephone        0755-86252656, 0755-86252388                   0755-86252656, 0755-86252388
Fax              0755-86252165                                  0755-86252165
                                                                lihongtao@joincare.com
E-mail           zhaofengguang@joincare.com
                                                                luoxiao@joincare.com


III. Introduction of the Company's basic information

Registered        Joincare Pharmaceutical Group Building, No. 17, Langshan Road, North District, Hi-tech
address           Zone, Nanshan District, Shenzhen
                    Registered at B5, Hengfeng Industrial City, Hezhou Community, Huangtian Village, Xin’an
                    Town, Bao’an County on 18 December 1992
                    Changed its registered address to 4-5/F, Dongpeng Building, Shangmeilin Industrial
                    Area, Futian District, Shenzhen on 25 May 1994
                    Changed its registered address to 24/F, Block B, Fujian Building, Caitian South Road,
                    Futian District, Shenzhen on 4 July 1995
                    Changed its registered address to 2 3 / F, Diwang Building, Shun Hing Square, No . 3 3 3 ,
Historical          Shennan East Road, Shenzhen on 20 June 1997
changes in
                    Changed its registered address to Taitai Pharmaceutical Industrial Building, the 5th
registered
                    Industrial Area, Nanshan District, Shenzhen on 22 September 2000
address
                    Changed its registered address to 23/F, Diwang Building, Shun Hing Square, No .5002,
                    Shennan East Road, Luohu District, Shenzhen on 4 June 2003
                    Changed its registered address to Joincare Pharmaceutical Group Building, No. 17,
                    Langshan Road, North District, Hi-tech Zone, Nanshan District, Shenzhen on 29 January
                    2008
                    Changed its registered address to Joincare Pharmaceutical Group Building, No. 17,
                    Langshan Road, North District, Hi-tech Zone, Nanshan District, Shenzhen on 27 November
                    2012
                  Joincare Pharmaceutical Group Building, No. 17, Langshan Road, North District, Hi-tech
Oce address
                  Zone, Nanshan District, Shenzhen
Postal code of
                  518057
Oce address
Website           www.joincare.com
E-mail            joincare@joincare.com


IV. Information disclosure and place for inspection


                                                        14
Joincare Pharmaceutical Group                                                                 Annual Report 2022




Designated media and website for disclosing China Securities Journal, Securities Times, Securities Daily, and
annual report                                Shanghai Securities News
Stock exchange website for disclosing annual
                                             www.sse.com.cn
report
The place for inspection of annual report    Oce address of the Company


V. Company stock profile

                                            Company Stock Profile
                                                                                       Stock abbreviation prior to
Class of stock    Listed on                   Stock Abbreviation         Stock code
                                                                                       change
A Share           Shanghai Stock Exchange              健康元              600380         太太药业, S健康元
                                              Joincare Pharmaceutical
GDR               SIX Swiss Exchange                                       JCARE                     /
                                              Group Industry Co., Ltd.


VI. Other relevant information

                                  Name                  Grant Thornton (Special General Partnership)
                                                        5th Floor, Scitech Palace, 22 Jianguomen Wai Avenue,
 Accounting firm appointed        Oce address
                                                        Chaoyang District, Beijing
 by the Company (domestic)        Name of the
                                  signing               Wang Yuan (王远) and Wang Qilai (王其来)
                                  accountants
                                  Name                  Minsheng Securities Co., Ltd.
                                                        17th Floor, Block D, Minsheng Financial Centre, 28
                                  Oce address
 Sponsor appointed for                                  Jianguomen Nei Avenue, Dongcheng District, Beijing
 performing the duty of           representatives
 continuous supervisory           signing the           Yu Chunyu (于春宇) and Ma Chujin (马初进)
 responsibilities during the      report
 Reporting Period                 Period of
                                  continuous            From 24 October 2018 to 31 December 2019
                                  supervision

Note: According to Article 29 of “Measures for the Administration of the Sponsorship Business for the Offering
and Listing of Securities”, for offering of new stocks or convertible corporate bonds by a company listed on the
main board, the period of continuous supervision and guidance shall be the remaining time of the current year
of the listing of securities and the following one full accounting year. As the Company issued shares to the public
by allotment on 24 October 2018, the period of continuous supervision should start from the completion of this
issuance and end on 31 December 2 01 9 . Furthermore, according to “Article 13 of the Guidelines of Shanghai
Stock Exchange for Self-Regulation Rules for Listed Companies No. 1 1 - Continuous Supervision”, the sponsor
shall continue to perform the obligations of continuous supervision if the funds raised have not been fully
utilized upon the expiration of the continuous supervision period. During the Reporting Period, funds raised in
this issuance have not yet been fully utilized, so the sponsor, Minsheng Securities, shall continue to perform its
continuous supervision obligations in respect of the deposit and utilization of the funds raised.


VII. Major accounting data and financial indicators in the last three years

(1) Major accounting data

                                                                                   Unit: Yuan Currency: RMB
                                                                              YoY Change
    Major accounting data              2022                  2021                                        2020
                                                                                 (%)
 Revenues                       17,142,753,068.82      15,903,688,266.59               7.79     13,521,605,768.20
 Net prot attributable to
 shareholders of the listed      1,502,595,840.48       1,328,499,432.05              13.10      1,120,439,799.25
 company


                                                        15
Joincare Pharmaceutical Group                                                                     Annual Report 2022


 Net prot attributable to
 shareholders of the listed
 company after deduction of      1,419,050,912.26      1,224,997,371.57                  15.84         966,680,220.14
 extraordinary gains and
 losses
  Net cash ow from
                                 3,977,705,139.29      2,563,089,045.24                  55.19       3,024,999,592.24
  operating activities
                                                                                   Increase or
                                                                                   decrease at
                                                                                 the end of the
                                    End of 2022            End of 2021            period over          End of 2020
                                                                                    the same
                                                                                 period of last
                                                                                     year(%)
 Net assets attributable to
 shareholders of the listed     13,121,820,410.55     11,820,293,656.69                  11.01      11,096,125,890.51
 company
 Total assets                   35,729,253,651.41     31,103,900,389.29                  14.87      28,156,977,599.07


(2) Major financial indicators

                                                                                      YoY Change
         Major nancial indicators                   2022            2021                                      2020
                                                                                         (%)
 Basic earnings per share (RMB/share)                  0.7933        0.6864                   15.57           0.5753
 Diluted earnings per share (RMB/share)                0.7921        0.6858                   15.50           0.5728
 Basic earnings per share after deduction
 of extraordinary gains and losses                     0.7492        0.6329                         18.38     0.4964
 (RMB/share)
                                                                                    Increased by 0.73
 Weighted average return on net assets (%)                 12.23         11.50                                  10.41
                                                                                    percentage points
 Weighted average return on net assets
                                                                                    Increased by 0.95
 after deduction of extraordinary gains and                11.55         10.60                                   8.98
                                                                                    percentage points
 losses (%)

Statement on major accounting data and nancial indicators within three years before the End of the
Reporting Period

√Applicable □N/A
The net cash flow from operating activities was RMB3,978 million, representing a year-on-year
increase of 55.19%, mainly due to the combined effect of an increase in sales receipts and a decrease
in payment of marketing expenses during the Reporting Period.

VIII. Differences in accounting data under domestic and foreign accounting standards

(1) Differences in net profit and net assets attributable to shareholders of the listed company
disclosed in the financial statements according to international accounting standards (IFRS)
and Chinese accounting standards (Chinese GAAP)
□ Applicable √ N/A

(2) Differences in net profit and net assets attributable to shareholders of the listed company
disclosed in the financial statements according to foreign accounting standards and Chinese
accounting standards
□ Applicable √ N/A

(3) Explanations on differences under domestic and foreign accounting standards:
□ Applicable √ N/A

IX. Major financial indicators in 2022 by quarter

                                                       16
  Joincare Pharmaceutical Group                                                              Annual Report 2022




                                                                                         Unit: Yuan Currency: RMB
                                      1st quarter            2nd quarter          3rd quarter           4th quarter
                                    (Jan. - Mar.)            (Apr.- Jun.)        (Jul. - Sept.)         (Oct. - Dec.)
Revenues                            4,657,343,538.89     3,907,601,746.66      4,447,021,452.61      4,130,786,330.66
Net prot attributable to
shareholders of the listed            460,537,813.53       340,730,705.97       325,293,433.73        376,033,887.25
company
Net profit attributable to
Shareholders of the listed
company after deducting               457,193,702.95       346,800,729.08       312,360,089.27        302,696,390.96
the extraordinary gains or
losses
Net cash flow from
                                      871,904,476.98     1,031,048,747.81       706,039,308.18      1,368,712,606.32
operating activities

  Statement on differences between quarterly data and the data disclosed in previous periodic
  reports
  □Applicable √N/A

  X. Items and amounts of extraordinary gains and losses
  √Applicable □N/A
                                                                                       Unit: Yuan Currency: RMB
      Item of extraordinary gains and losses              2022                2021                   2020
    Gain or loss on disposal of non-current
                                                          -705,357.30        14,492,047.24        102,634,566.25
    assets
    Government grants recognized in profit or
    loss for the current period (excluding
    government grants that are closely related
    to the business of the Company and are             286,842,932.33       245,335,140.69        246,707,925.30
    provided in fixed amount or quantity
    continuously according to the applicable
    polices and standards of the country)
    Profit or loss on debt restructuring                          0.00                0.00           -298,617.11
    Gains and losses on fair value changes
    incurred from financial assets held for
    trading, derivative financial assets,
    financial liabilities held for trading and
    derivative financial liabilities, and
    investment income on disposal of financial
                                                       -109,887,696.11        8,110,644.25         48,458,672.96
    assets held for trading, derivative financial
    assets, financial liabilities held for trading,
    derivative financial liabilities and other
    debt investments, except for effective
    hedging activities related to the ordinary
    operating business of the Company
    Reversal of impairment loss on accounts
    receivable and contract assets tested for              158,470.77         1,013,650.67                  0.00
    impairment individually
    Other non-operating income and expenses
                                                        -23,830,838.49      -30,737,442.83        -22,794,516.25
    apart from the above items
    Less: Effect of income tax                          31,919,034.26        39,580,260.30         51,541,134.41
          Effect of minority equity (after tax)         37,113,548.72        95,131,719.24        169,407,317.63
                         Total                          83,544,928.22       103,502,060.48        153,759,579.11

  Explanations for the Company’s extraordinary gain or loss items as defined in the ‘“Explanatory
  Announcement No.1 for Public Company Information Disclosures – Extraordinary Gains or
  Losses’”, and the extraordinary gain or loss items as illustrated in the ‘“Explanatory Announcement
  No.1 for Public Company Information Disclosures – Extraordinary Gains or Losses’” which has
  been defined as its recurring gain or loss items.
  □ Applicable √ N/A

                                                            17
Joincare Pharmaceutical Group                                                     Annual Report 2022




XI. Items measured at fair value
√ Applicable □ N/A

                                                                             Unit: Yuan Currency: RMB
                                                                Change for the      Effect on profits &
         Item            Beginning balance   Ending balance
                                                                   period          losses for the period
 Financial assets
                            184,638,344.31    109,015,664.98     -75,622,679.33        -113,211,242.08
 held for trading
 Other equity
 instrument               1,408,882,377.42   1,193,958,879.05   -214,923,498.37          18,713,637.23
 investments
 Financial liabilities
                                143,302.24        755,634.43         612,332.19            -612,332.19
 held for trading
        Total             1,593,664,023.97   1,303,730,178.46   -289,933,845.51         -95,109,937.04

XII. Others
□ Applicable √ N/A




                                                   18
Joincare Pharmaceutical Group                                                  Annual Report 2022




                  Chapter 3 Management Discussion and Analysis


I. Discussion and analysis of business operation

2022 was a crucial year for China to promote the implementation of the “14th Five-Year” Plan and
the 30th anniversary of the establishment of Joincare. Facing the complex and volatile external
environment and various unexpected hardships and challenge, the Company adhered to the
corporate vision of “Diligently make high-quality and innovative drugs” and the core values of
“Putting People First, Valuing Workmanship and Quality, Pursuing Innovation and Truth, Promoting
Cooperation and Sharing”, and achieved sustained and stable growth by focusing on its principal
business, fully leveraging its comprehensive strengths, increasing investments in R&D to improve
its innovative capability, optimizing the product structure at a faster pace and adapting to the in-
depth market-oriented reform and innovation of the marketing system.
(I) Focusing on innovative drugs and high-barrier complex formulations to promote high-
quality development

Driven by R&D and innovation, the Company has been concentrating on developing innovative
drugs and high-barrier complex preparations to meet the needs of patients. The Company carried
out the R&D of differentiated products covering the full lifecycle of drugs, gradually broke through
technological barriers in segmented industries and developed competitive advantages in the market.
While deeply cultivating inhalation administration, sustained-release microspheres, antibody
technology and other platforms with technical strength, the Company continued to develop and
deploy on platforms for complex injections represented by nanocrystals and liposomes and
constantly consolidated the leading position of the Company in the domestic high-end complex
formulations. During the Reporting Period, the Company made a significant headway in developing
multiple medicines in our R&D pipeline and sped up the innovation process. Tobramycin Solution
for Inhalation (妥布霉素吸入溶液) was approved for market launch. The Recombinant SARS-
CoV-2 Fusion Protein Vaccine (Likang) was successfully included for the emergency use for
heterologous booster vaccination. Indacaterol Maleate Powder for Inhalation (马来酸茚达特罗吸
入粉雾剂) and Ilaprazole Sodium for injection (注射用艾普拉唑钠) with new indication had
applied for production. Salmeterol Xinafoate-Fluticasone Propionate Powder for Inhalation (沙美
特罗替卡松吸入粉雾剂), Aripiprazole Microspheres for Injection (注射用阿立哌唑微球) (1-
month sustained release), Recombinant Anti-human IL-17A/F Humanized Monoclonal Antibody
for Injection (重组抗人 IL-17A/F 人源化单克隆抗体注射液) and XYP-001 were currently under
clinical studies. The Company has been paying attention to the R&D of drug-device combinations.
Two products developed by the Company have obtained the registration certificates of class II
medical devices and one product has obtained the filing certificate for medical devices.

While continuously strengthening independent innovation, the Company has been paying close

                                                19
Joincare Pharmaceutical Group                                                   Annual Report 2022


attention to cutting-edge technologies, enhancing external cooperation and actively promoting
innovative business cooperation models in global market. It has been actively seeking opportunities
for frontier technology expansion and global product layout through cooperative development and
licensing, among other means, to strengthen its commercialization and integration capabilities. The
Company has been strengthening the licensing on introduction of products in core sectors,
authorizing the introduction of various projects in the fields of respiratory, psychiatry and
gastroenterology and expanding the R&D pipeline of the Group. It has made phased progress in
collaborative projects. XYP-001 and Asenapine transdermal patch licensed-in were approved for
clinical trials in China. Moreover, the Company succeeded in exporting its products under research,
with its R&D strength gradually recognized by overseas markets. The Company is still continuously
advancing international cooperation and licensing on innovative products and pipelines, and
conducting negotiations on cooperation with various parties in the international community. For
Tobramycin Inhalation Solution (妥布霉素吸入溶液), an modified new drug, the Company is
conducting negotiations on licensing with customers in Europe, Southeast Asia and other regions.
(II) Innovating a diversified marketing model to enhance corporate brand value

In 2022, the marketing teams of prescription medicines actively implemented the sales strategies
and completed the following key tasks: strengthening product and brand promotion, integrating
resources of end-users, focusing on appraisal of hospitals at above grade II, and enhancing the
hospital coverage of core brands and fulfillment rate of evaluation indicators. During the Reporting
Period, the hospital coverage rate of key products continued to rise, and the overall sales revenues
of prescription medicines showed a steady increase compared with the previous period. As Online
and offline linkage of prescription drugs were enhanced, and with “patients” as the starting point,
online digital marketing was continuously promoted, content construction on doctors intensified,
diseases management knowledge spread, cooperation between hospitals and chain pharmacies
deepened, and offline patient services, brand reputation and patient satisfaction improved. We
continued to carry out evidence marketing, boost academic marketing and maintain close
communication with domestic and international academic communities. Tobramycin Inhalation
Solution (妥布霉素吸入溶液), Ilaprazole series(艾普拉唑系列) and other key products were
incorporated into several core guides and clinical consensus. The clinical and pharmacoeconomic
study for key products went on smoothly, boosting continuous growth of products. We actively
follow up the implementation of policies on national medical reform, and two products are included
into the 7th round national volume-based procurement to reduce the price and improve the
accessibility to patients.

Actively expanding overseas markets remained the focus for API marketing this year. Against the
backdrop of the complicated and severe global economic situation and increasingly fierce
competition in API sales in 2022, the sales team of the Company deeply explored in the market and
advanced against headwinds, achieving remarkable performance. The Company increasingly
became the preferred strategic partner of global leading pharmaceutical enterprises. Sales of high-

                                                 20
Joincare Pharmaceutical Group                                                      Annual Report 2022


end antibiotics and high-end pet drugs achieved remarkable growth. More than ten products further
consolidated their advantages while maintaining the biggest market share in the global export
market. In addition, after over ten years of development, the pet API of the Company occupied a
large global market share, and it has established strategic partnerships with many multinational
animal healthcare companies. The Company’s first pet formulation product - Imidacloprid and
Moxidectin Spot-on Solutions (吡虫啉莫昔克丁滴剂)-had been launched for sale in 2022.
(III) Attaching equal importance to quality and efficiency, and entering a new stage of
internationalization

Adhering to the concept that quality, safety and environmental protection are the lifeline, the
Company conducted systematic control of quality and safety risks, improved the management
mechanism, and increased investment in safety and environmental protection, to ensure production
safety and stable quality of drugs. At the same time, the Company always adheres to the principle
of sustainable development and integrates the concept of green development into operation and
management processes. It promoted lean production of major products through green chemical
technological means and the improvement and upgrading of equipment and facilities to improve the
production efficiency, achieving comprehensive cost reduction and efficiency improvement. While
constantly consolidating the foundation for environmental protection and safety, improving the
quality study on existing products, optimizing the production process, and promoting the
normalization of GMP, all production enterprises have been actively applying for international
certification, thus the internationalization process is further accelerated.

With respect to formulation products, the Company strengthened overseas market access, product
registration   and    promotion    of    inhalation     products,   assisted   reproductive   products,
gastroenterological products, antiviral products, etc. Ilaprazole Sodium for injection (注射用艾普
拉唑钠) and Ilaprazole Enteric-Coated Tablets (艾普拉唑肠溶片), key products of the Company,
were approved to be launched for market in Indonesia. The work related to overseas registration of
Recombinant Human Choriogonadotropin alfa for Injection (注射用重组人绒促性素) is being
promoted, the submission of registration materials has been completed in Indonesia, Pakistan, five
countries in Central and South America and 2 countries in Central Asia, and it has been approved to
be launched for market in Tajikistan. Budesonide Suspension for Inhalation (布地奈德吸入混悬
液), Compound Ipratropium Bromide Solution for Inhalation (吸入用复方异丙托溴铵溶液) and
other products are undergoing registration in the Philippines and other countries. Budesonide
Suspension for Inhalation has completed registration in Macau and the company completed the first
overseas sale of inhaled formulation products. With respect to APIs, during the Reporting Period,
the Company obtained 4 international authentication certificates for APIs and intermediates, namely
1 EU GMP certificate for Teicoplanin (替考拉宁) and Vancomycin Hydrochloride (盐酸万古霉素);
and 3 CEP certificates, namely the CEP certificate for Moxidectin (莫昔克丁), the CEP certificate
for Acarbose (阿卡波糖) and the CEP certificate for Tobramycin (妥布霉素).



                                                   21
Joincare Pharmaceutical Group                                                    Annual Report 2022


(IV) Implementing scientifically-based lean management and improving the overall operating
efficiency

During the Reporting Period, the Company ensured that the management processes follow the
development of the Company by improving the management efficiency through formulating and
optimizing management processes and strengthening standardized operation and risk control. The
Company raised higher requirements and targets on work related to the sustainable development,
released appraisal rules on ESG indicators and actively performed social responsibilities. The
Company intensified the management by an objective system with OKRs and KPIs in parallel, with
full cooperation and support from all functional departments to provide strong services and
guarantee for R&D, production and marketing, attached great importance to talent acquisition and
team building, implemented the A/B role working mechanism, enhanced the working capability of
employees, continued to introduce global high-end talents while strengthening identification,
training and promotion of internal talents to ensure stability of the core talent team, actively
disseminated the corporate culture and developed highly unified core values of enterprises to
enhance their sense of happiness and enterprise identity, so as to achieve greater cohesiveness and
affinity in the workplace.
(V) Practicing corporate social responsibility to boost sustainable development

The Company adhered to the path of green development and facilitated the achievement of “carbon
peaking and carbon neutrality” targets with practical actions. Through the formulation of the
“Energy Conservation and Emission Reduction Targets 2021-2025”, it continuously promotes all
its production enterprises to carry out energy saving and emissions reduction and complete the
environmental management targets for 2022. During the Reporting Period, the Company introduced
the Environmental Management Targets on Carbon Emissions and strived to achieve carbon
neutrality by 2055. While focusing on its own development, the Company always participates in
social welfare initiatives and vigorously undertakes social responsibilities. The Group has actively
responded to national policies and calls for years. In combination with its own industrial advantages,
the Group jointly launched the “Access to Public Welfare for Chronic Diseases Prevention and
Treatment ( 普 惠 慢 病 防 治 公 益 项 目 )”program, which currently covers 8 provinces and 1
autonomous region. It provided drugs and other materials for patients with chronic diseases in
remote areas, alleviated their medical burdens and further improved the affordability of drugs. In
addition, the Company actively conducted public welfare and science popularization activities,
deeply spread knowledge on diseases through preparing videos on public welfare and science
popularization, invited experts to conduct livestreaming on public welfare and science
popularization, and hosted public welfare lectures. It carried out bronchiectasis assistance programs
as well. Through the “Enterprise WeCom Expert’s little helper”, it provided one-to-one services for
bronchiectasis patients and offered medication consultation, disease consultation, free expert
diagnosis and other services. In 2022, the Company’s public welfare donations amounted to
approximately RMB12.117 million.

                                                 22
Joincare Pharmaceutical Group                                                   Annual Report 2022


II. Overview on the industry in which the Company operates during the Reporting Period

The pharmaceutical industry is a national strategic emerging industry bearing on the national
economy and people's livelihood, and an important part of the national economy. According to the
14th Five-Year Plan for the Development of Pharmaceutical Industry(《“十四五”医药工业发展规
划》), the overall development of the pharmaceutical industry will reach a new level. During the
"13th Five-Year Plan" period, the average annual growth rate of the added value of pharmaceutical
industry above designated scale was 9.5%, 4.2 percentage points higher than the overall growth rate
of all the industries, and the proportion of the total added value of the pharmaceutical industry to
that of all the industries increased from 3.0% to 3.9%; the average annual growth rate of the
operating revenues and total profit of enterprises above designated scale were 9.9% and 13.8%,
respectively, being at the forefront of various industries in terms of growth rate. At the same time,
the scale of leading pharmaceutical manufacturers has further expanded with the steadily increasing
industry concentration. In 2022, with the deepening reform of the national medical and healthcare
system and increasing improvement in the innovation environment, the pharmaceutical industry
continued to advance towards high-quality development featuring transformation as well as
upgrading and encouraging innovation. With the aging population and the increasing urbanization
rate in China, from the long-term and holistic perspective, China's pharmaceutical industry will
continue to present a promising development trend.

The R&D expenditures in new drugs in the pharmaceutical industry remained high and the pipeline
of new drugs under research was increasingly diversified. In 2022, 10 innovative chemical drugs,
31 modified new chemical drugs, 6 innovative biological drugs and 5 new TCM drugs were
approved for market launch. The number of new drugs approved for market launch remained
relatively stable. Meanwhile, the time from the launching of innovative drugs to the inclusion in the
medical insurance system was shortened from the original 4-5 years to the current about 1 year. The
application of innovative drugs with “clinical value” in hospitals was further accelerated. Data of
National Bureau of Statistics shows that in 2022, enterprises in the pharmaceutical manufacturing
industry above designated scale in China recorded revenues of RMB2,911.14 billion, representing
a year-on-year decrease of 1.6%; operating costs of RMB1,698.46 billion, representing a year-on-
year increase of 7.8%; and total profits of RMB428.87 billion, representing a year-on-year decrease
of 31.8%.
III. Overview on the businesses of the Company during the Reporting Period
(I) Principal businesses and products of the Company
The Company is primarily engaged in the R&D, production and sales of pharmaceutical products
and health care products. The business scope of the Company covers chemical pharmaceuticals,
biologics, chemical active pharmaceutical ingredients (APIs) and intermediates, traditional Chinese
medicine, diagnostic reagents, equipment, health care products, etc. The comprehensive product
series and mix provide larger market and growth opportunities for the Company. Main products of
the Company are as follows:

                                                 23
Joincare Pharmaceutical Group                                                   Annual Report 2022




(II) Business model of the Company

With the stable operation and rapid development over the years, the Company has become an
integrated pharmaceutical group that is driven by scientific research and innovation, integrating the
R&D, production, sale and service of pharmaceutical and health care products. It has complete
systems of R&D, procurement, production and sale. Main business models of the Company are as
follows:

1. R&D

Taking independent R&D as the mainstay and combining external introduction and cooperative
development, the Company has been paying attention to the cutting-edge technology and unmet
clinical needs, with efforts focused on innovative drugs and high-barrier complex formulations and
has established an efficient R&D innovation management model. In terms of independent
innovation, the Company has a diversified and multi-dimensional R&D organization with mature
R&D teams for chemical pharmaceuticals, biologics, TCM drugs, APIs, diagnostic reagents and
health care products. Based on technology platform construction, the Company has built a clear
product R&D pipeline centering on key areas such as respiratory, tumor immunity and psychiatry.
In terms of cooperative innovation, the Company has launched technical cooperation with domestic
and foreign scientific research institutions by way of commissioned development or cooperative
development, and has introduced new technologies and products that meet the strategic development
goal of the Company through technology transfer or license-in to implement industrial

                                                 24
Joincare Pharmaceutical Group                                                  Annual Report 2022


transformation, so as to reinforce and strengthen our position and strategy in the leading and
emerging fields.

2. Procurement

In terms of procurement, the Company pays strict attention to effectiveness, quality and cost of
procurement and has established long-term and stable partnership with many suppliers. Active
pharmaceutical ingredients, supplementary materials, and packaging materials were purchased and
stocked up by manufacturers according to production schedules. The Company has developed strict
quality standards and procurement management systems and required subordinate manufacturers to
make procurements in accordance with the GMP. Meanwhile, the Company established long-term
strategic partnerships with bulk material suppliers, and strengthened the management of supply
quality and cost control based on strict quality standards. The Company has established an internal
evaluation system and files of market prices so as to promptly acquire market information for
procurement through comparisons of quality and price.

3. Production

In terms of production, the Company adopts the principle of market demand-oriented approach
paying attention to real market demand. Specifically, the Sales Department of the Company
investigated market demands, made sales plans, and comprehensively considered factors such as
the product inventory quantity and capacity of production lines of the Company so as to determine
the monthly production quantities and specifications. Moreover, the purchase orders of raw
materials are determined according to the production schedule and the inventory levels of raw
materials. The final production plans are issued upon approval of the management of the Company
and implemented by the Production Technology Department of the Company.

The Company has been carrying out production in strict accordance with the GMP. The Company
and its affiliates have established a sound quality management system and implemented the
qualified-person system. In terms of quality control, the Company has established a strict and sound
production quality assurance system, and is geared to international standards and subject to
international certification while in compliance with national standards. The Company conducts
annual GMP self-inspection, ISO9001 internal and external audits, and is subject to various external
audits. It actively pursued the internationally advanced GMP management, and implemented whole-
process quality control over supplier selection, audit, incoming material inspection, production
process, product release from factory, and market tracking. The system is running well.

4. Sales

(1) Drug formulation products

End customers of drug formulation products (chemical pharmaceuticals, biologics, traditional
Chinese medicine) of the Company are mainly hospitals, clinics, and retail pharmacies. In line with


                                                25
Joincare Pharmaceutical Group                                                     Annual Report 2022


the pharmaceutical industry practice and the sales model of most peers in the industry, the Company
has conducted sales of drug formulation products through drug distribution enterprises. The
Company carried out selection and centralized management of qualified drug distribution
enterprises (with Drug Supply Certificate, GSP Certification, etc.) according to their distribution
capability, market familiarity, financial strength, credit record, and operation scale. General sales
process: After end customers place purchase orders to distribution enterprises, drug distribution
enterprises will send those orders to the Company according to their inventories, distribution
agreements and conditions; then, the Group will deliver products to drug distribution enterprises
and do the revenue recognition.

 (2) APIs and intermediates

Main target customers of APIs are large pharmaceutical manufacturers. The selling prices are
determined based on a set of integrated factors such as costs of production, inventory levels, industry
rivalry and market trend. Specific pricing method: The sales and marketing department conduct
weekly or bi-weekly meetings to analyze the current market conditions, the trends and drivers of
prices; the selling prices are determined based on a set of comprehensive factors such as costs of
production, inventory levels, industry rivalry and market conditions; the selling prices will be
effective once are reported by the managers of the sales department to our management team and
get approvals.

Specific sales methods of APIs include: ① Domestic market: The Company directly signs product
sales contracts with large manufacturers to directly sell products to customers. Meanwhile, the
Company also sells products through distributors. ② Foreign market: The Company directly sells
products in the foreign market and in areas with high market and political risks, products are sold
through distributors. At present, products of the Company are mainly exported to over 60 countries
and regions in Asia, Europe, North America, and Africa.

(3) Diagnostic reagents and equipment

Diagnostic reagents and equipment sold by the Company both domestically manufactured and
imported. Main end customers are hospitals, centers for disease control and prevention, and health
departments. The Company mainly sells those products in combination with direct sales and sales
through drug distribution enterprises.

The Company has an experienced sales team responsible for the sales of diagnostic reagents and
equipment, with provision of marketing support for some drug distribution enterprises. The
Company carried out selection and centralized management of qualified drug distribution
enterprises (with Drug Supply Certificate, GSP Certification, etc.) according to their distribution
capability, market familiarity, financial strength, credit record, and operation scale.




                                                  26
Joincare Pharmaceutical Group                                                    Annual Report 2022


(4) Health care products

The sales model of health care products is mainly distributor management model. Product
promotion, price control, and channel carding are managed and improved with the distributor
distribution channel and terminal coverage capability. At present, the Company has set up 25
provincial branches and 92 subordinate offices across China and maintained long-term partnership
with distributors with better area coverage capability for stable strategic alliance and common
development. The Company has cooperated with about 103 first-level/primary distributors in total,
including 78 businesses in drug distribution line and approximately 25 businesses in food
distribution line with more than 150,000 subordinate secondary businesses and terminal businesses
in drug and food distribution lines. Products are well managed and promoted through the tiered
marketing channel. In addition to the traditional distribution management model, the Company
realizes synergetic development through online channels. At present, the Company has set up
official flagship stores on mainstream e-commerce platforms such as Tmall(天猫), Jingdong(京
东), Douyin(抖音), Kuaishou (快手) and Pinduoduo (拼多多).

(III) Industry status of the Company

Through years of development, the Company has become a comprehensive pharmaceutical
enterprise covering multiple areas including chemical pharmaceuticals, biologics, chemical APIs
and intermediates, traditional Chinese medicine, diagnostic reagents and equipment, health care
products, etc. In terms of revenues in 2021, the Company ranked sixth among the listed integrated
pharmaceutical enterprises in China. Chemical pharmaceuticals are the largest revenue generator of
the Company, among which gastroenterological products, anti-infection products and gonadotropic
hormones products are traditional competitive products of the Company, with key products securing
a long-standing leading position in national drug formulation market segment. Respiratory and
psychiatric products have been the focus of the Company, with key products maintaining a strong
sales growth momentum.

In terms of R&D expenditures in 2021, the Company ranked fifth among listed integrated
pharmaceutical enterprises in China. During the Reporting Period, with solid strength in R&D,
production, and steady marketing presence, the Company ranked Top 10 in 2021 Annual Ranking
of Top 100 Chinese Chemical Drug Enterprises and Top 100 in the “2022 Annual Ranking of
Chinese Pharmaceutical R&D Comprehensive Strength”.

(IV) Performance drivers during the Reporting Period

In 2022, the Company actively implemented sales deployment, strengthened market promotion and
reinforced sales specialization. In addition, the Company increased digital marketing and enhanced
delicacy management. That is how we can realize steady growth of main business revenues and
consolidate the foundation and ability of sustainable development of enterprises. During the
Reporting Period, sales of main varieties in key specialist areas, especially in fields of respiratory


                                                 27
Joincare Pharmaceutical Group                                                   Annual Report 2022


and psychiatry of the Company, kept steady growth, and contribution of sales revenues from key
preparation products to overall revenues was continuously improved. In addition, the proportion of
sales and profit of high-end APIs increased as the Company has been taking measures to integrate
resources, optimize product structure, and reinforce international certification while actively using
advanced technologies including synthetic biology and continuous production to ensure green
production.
IV. Analysis of core competitive strengths during the Reporting Period

√Applicable □N/A

1.   Leading integrated pharmaceutical company under continuous innovation and
development in China

The Company is primarily engaged in the R&D, production and sale of pharmaceutical products
and health care products. The business scope of the Company covers chemical pharmaceuticals,
biologics, chemical APIs and intermediates, TCM drugs, diagnostic reagents and equipment, as well
as health care products, allowing the Company to establish competitive advantages across various
therapeutic areas such as respiratory, anti-infection, assisted reproduction, gastroenterology,
psychiatry, and tumor immunity. 1) Innovative R&D drives growth: The Company has developed
and launched a number of innovative medicine products and high-barrier complex formulation
products, strengthening the Group’s product portfolio and drug candidates in the pipeline. 2) The
Company has first-tier commercialization ability, and its sales network covers all provinces in China
and over 80 overseas countries and regions in the world. The Company emphasizes scientific
promotion and evidence-based marketing. By building a professional marketing team, the Company
has established a comprehensive marketing system, and market education and brand building have
been deeply strengthened through digital marketing. Leveraging our comprehensive sales channels,
broad market coverage, leading digital marketing and brand awareness, the Company is able to sell
the products at scale in an efficient manner. 3) Cross-industry and multi-specialist innovative R&D
and coordinated development: On one hand, the Company actively adapts to the changes in the
pharmaceutical market and constantly adjusts its product strategy and R&D direction according to
policies and clinical needs. This will realize the continuous iteration and upgrade of the main
products. On the other hand, the Company fully utilizes external scientific research and commercial
resources, such as strategic collaboration with Chinese Academy of Sciences, Tencent Quantum
Lab and other scientific research institutes and innovative companies and invests in cutting-edge
biotechnology companies to expand the Company’s product portfolio and R&D pipeline, thus
realizing the Company’s sustainable development.




                                                 28
Joincare Pharmaceutical Group                                                  Annual Report 2022



2. Strong R&D capabilities, diversified product portfolio and leading commercialization

capabilities

Focusing on innovative medicines and high-barrier complex formulation, the Company has formed
diversified product portfolio. With the huge clinical demand and high product quality, it has
established market competitive advantages in many pharmaceutical segments. The Company’s
chemical pharmaceuticals cover gastroenterology, assisted reproduction, anti-infection, respiratory,
psychiatry, tumor and other fields, among which alimentary tract proton pump inhibitor (PPI) drugs,
gonadorelin hormone drugs, and inhalation formulation for respiratory diseases have an
advantageous market position. Relying on APIs production, the Company’s core products, together
with our chemical APIs and intermediates, form an integrated and stable pharmaceutical industrial
chain of “APIs-formulations vertical integration”. Meanwhile, the Company actively develops
overseas markets, and our products are marketed and distributed worldwide, facilitating strategic
cooperation with many internationally renowned pharmaceutical companies. In addition, the
Company also has a number of TCM drugs and in vitro diagnostic reagent products and has
accumulated resources and extensive brand influence in healthcare products for many years.

3. Making breakthroughs in the key R&D and industrialization technologies of complex

formulation

The technology platform, which has been developed over the years in the field of innovative
medicines and high-barrier complex formulation, enables the Company to address the complex
process problems in the R&D and production of relevant drugs. Guided by clinical value, the
Company develops R&D projects with high short-term certainty and cutting-edge technologies with
long-term growth potential (such as AI-driven drug molecular design, proteolysis targeted chimeric
(PROTAC), synthetic biology, gene-editing, cellular treatment, etc.). All in all, the Company’s
R&D system covers through-cycle of drug development and production. Based on the mature R&D
platform of innovative drugs and high-barrier complex formulations, the Company has designed
extensive pipeline in fields with significant clinical demand such as respiratory, gastroenterology,
assisted reproduction, psychiatry, and tumor.

4. Stable management and R&D team with expertise, long-term vision and commitment to

social responsibility

The Company has a stable, visionary and experienced, results-oriented management team and an
outstanding talent team. Outstanding leaders are the key to the Company’s rapid development. The
founder of the Company has over 30 years of expertise in the pharmaceutical industry as well as a
global vision and a strategic mindset. With a deep industry insight, the founder has led us develop
platform technologies centered on high-barrier complex formulations, which has established leading
position of the Group with sustainable development in the broader healthcare industry. The senior


                                                29
Joincare Pharmaceutical Group                                                     Annual Report 2022


management team of the Company has over 20 years of industry experience on average, with an
average of more than 10 years of service in the Company, and has a thorough understanding of
market demand, industry development and growth opportunities. Each key R&D field of the
Company is led by industry-leading scientists and accompanied by an efficient R&D management
team. In addition, the Company has upheld the core value of “Putting People First, Valuing
Workmanship and Quality, Pursuing Innovation and Truth, Promoting Cooperation and Sharing”
and laid emphasis on talent team training to build a diversified reserve of talents with global vision,
advanced knowledge, strong implementation capability and sense of self-reliance. Driven by the
corporate culture of pursuing excellence, the talent team works diligently and conscientiously to
jointly contribute to the sustainable development of the enterprise through teamwork and
collaboration.

V. Overview of business operations during the Reporting Period

During the Reporting Period, the Company realized revenues of RMB17,143 million, representing
a year-on-year increase of approximately 7.79%; a net profit attributable to shareholders of the listed
company of RMB1,503 million, representing a year-on-year increase of approximately 13.10%, and
a net profit attributable to shareholders of the listed company after deducting the extraordinary gains
or loss of RMB1,419 million, representing a year-on-year increase of approximately 15.84%. In
2022, business development of various segments of the Company is as follows:

(1) Livzon Group (excluding Livzon MAB)

As at the End of the Reporting Period, the Company directly and indirectly held 44.77% equity
interest in Livzon Group (000513.SZ, 01513.HK). During the Reporting Period, Livzon Group
(excluding Livzon MAB) realized revenues of RMB12,424 million, representing a year-on-year
increase of approximately 3.35%; and realized a net profit of approximately RMB1,038 million
attributable to shareholders of the Company.

During the Reporting Period, the sales of the drug formulation segment of Livzon Group increased
steadily, and recorded the steady growth in the proportion and profitability of high-end specialty
APIs in the API segment. The sales of its products in the key therapeutic areas are as follows:
Gastroenterology products realized revenues of RMB3,436 million, representing a year-on-year
decrease of approximately 6.48%; gonadotropic hormones products realized revenues of RMB2,591
million, representing a year-on-year increase of approximately 5.64%; and psychiatry products
realized revenues of RMB545 million, representing a year-on-year increase of approximately
32.19%.

(2) Livzon MAB

As at the End of the Reporting Period, the equity interest directly and indirectly held by the
Company in Livzon MAB was 55.90%, and the amount affecting the Company's net profit
attributable to the parent company for the current period was approximately RMB-446 million.

                                                  30
Joincare Pharmaceutical Group                                                   Annual Report 2022


During the Reporting Period, Livzon MAB focused on promoting the application on conditional
marketing approval of the Recombinant SARS-CoV-2 Fusion Protein Vaccine (重组新型冠状病
毒融合蛋白疫苗) (Likang). Livzon MABcompleted the Phase III clinical master analysis report
for sequential immunization and basic immunization and submitted related application materials to
CDE in February and May 2022, respectively. It was approved for the domestic heterologous
booster vaccination in June 2022 and was officially included into the national immunization plans
in September of the same year. Currently, it has been applied in the booster vaccination in over 20
provinces and municipalities across China. To meet the market demand, Livzon MAB has
completed the construction of the third preparation workshop (2-tests and 10-tests production line),
which has been fully put into operation, on the basis of the existing 1 stock solution production line
and 2 preparation production lines. In addition, in response to the global trend of COVID-19
pandemic and the prevalence of COVID-19 variants, Livzon MAB developed several vaccines
against the variants and related bivalent vaccines and carried out explorations on enhanced
immunization with portfolios of various types of vaccines. During the Reporting Period, Livzon
MAB carried out the R&D of bivalent vaccine BV-01-B5 on prototype strain + Omicron strain.
Data showed that BV-01-B5 has outstanding cross-neutralization effects on Omicron BA.4/5 and
other subtypes. Currently, complete clinical application materials for the bivalent vaccine have been
submitted and are under CDE’s review.

On the other hand, Livzon MAB continued to focus on new molecules, new targets and
differentiated molecular designs in the fields of tumors, immune diseases and assisted reproduction.
During the Reporting Period, Livzon MAB made phased progress in the R&D of the following
projects: Recombinant Human Choriogonadotropin alfa for Injection (注射用重组人绒促性素)
was approved for launching in 2021 and had started sales, which is the first generic drug of its kind
in China. Livzon MAB had been actively promoting overseas registrations. Its submission of
registration materials had been completed in Indonesia, Pakistan, five countries in Central and South
America and 2 countries in Central Asia and the drug had been approved for launching in Tajikistan.
The application for launch approval on Tocilizumab Solution for Injection (托珠单抗注射液) (i.e.
Recombinant Humanized Anti-human IL-6R Monoclonal Antibody Solution for Injection (重组人
源化抗人 IL-6R 单克隆抗体注射液) , with the indication of rheumatoid arthritis, had been
approved. Meanwhile, it was listed in the Diagnosis and Treatment Protocol for COVID-19 (Trial
Version 10) and the Diagnosis and Treatment Protocol for Severe COVID-19 Cases (Trial Version
4). With tight domestic supply of brand-name drugs at the end of 2022 and the beginning of 2023,
the approval for market launch of Tocilizumab Solution for Injection of Livzon MAB relieved the
tight supply to a certain extent. The phase II clinical trials for Recombinant Anti-human IL-17A/F
Humanized Monoclonal Antibody for Injection (重组抗人 IL-17A/F 人源化单克隆抗体注射液)
were completed and Livzon MAB was about to conduct the phase III clinical trials. Results showed
that such product has fast action, outstanding efficacy, long maintenance of efficacy and other
clinical advantages. It has better efficacy than IL-17A single-target drug and is expected to provide


                                                 31
Joincare Pharmaceutical Group                                                   Annual Report 2022


better solutions for psoriasis treatment in China. Moreover, the product with ankylosing spondylitis
indication jointly applied for clinical trial by Livzon MAB and Beijing Kanova was under the
preliminary analysis of interim data of the phase II clinical trials.

In addition to advancing projects in the clinical phase, Livzon MAB is also exploring through R&D
in areas such as bispecific antibodies and NKT cell therapy. With more and more products approved
for market launch, Livzon MAB expanded its pharmacovigilance, production quality, production
and sales linkage and other relevant teams, gradually enhanced the GMP system and
industrialization capability and improved the overall operational capability.

(3) Joincare (excluding Livzon Group and Livzon MAB)

During the Reporting Period, Joincare (excluding Livzon Group and Livzon MAB) realized
revenues of RMB4,832 million, representing a 17.04% year-on-year increase of approximately, and
realized a net profit attributable to shareholders of listed companies of RMB929 million,
representing a year-on-year increase of approximately 43.00%. Joincare realized a net profit
attributable to shareholders of the listed company after deducting the extraordinary gains and losses
of RMB863 million, representing a year-on-year increase of approximately 39.73%. Key results of
the main business segments are as follows:

①   Prescription medicines

During the Reporting Period, Joincare (excluding Livzon Group and Livzon MAB) realized sales
revenues of RMB2,120 million from prescription drug segment, representing a year-on-year
increase of approximately 18.46%. Among which, the sales revenues and year-on-year change of
key therapeutic areas are as follows: the revenues generated from the field of respiratory totaled
RMB1,174 million, representing a year-on-year increase of 103.37%; the revenues generated from
the field of anti-infection totaled RMB921 million, representing a year-on-year decrease of 22.76%.

In 2022, the Company gradually enhanced the national sales team in respiratory line, established a
three-level fine marketing development system of regional managers, provincial managers, and
development managers, actively taking various measures to speed up the penetration of key products
into hospitals: 1. The coverage and fulfillment rate of evaluation indicators were enhanced; the
development speed of respiratory variety was obviously accelerated; drug formulary expansion of
more than 2,200 hospitals above grade II was newly conducted throughout the year; 2. Rapid
coverage and sales growth of the Levosalbutamol Hydrochloride Nebulizer Solution (盐酸左沙丁
胺醇雾化吸入溶液) was realized by taking the opportunity that the drug was included in the China’s
National Reimbursement Drug List (“NRDL”); 3. Construction of digital marketing platforms was

continuously advanced, marketing process accelerated through digital means and the brand
comprehensively communicated via the platform of “Respiratory Experts' Views” (呼吸专家说);
4. With three inhalation formulations being included to the fifth batch of the volume-based
procurement and one inhalation formulation being included to the seven batch of the volume-based

                                                   32
Joincare Pharmaceutical Group                                                  Annual Report 2022


procurement, the Company has rapidly tapped into the domestic sales market and gradually
improved market share for inhalation formulation products; 5. Construction of regional warehouses
in 10 regions across the country completed, including Shijiazhuang, Wuhan and Zhengzhou and
were put into operation in 2022, which effectively ensured the timely and efficient distribution of
drugs.

②   APIs and intermediates

During the Reporting Period, Joincare (excluding Livzon Group and Livzon MAB) realized sale
revenues of RMB2,360 million from APIs and intermediates segment, representing a year-on-year
increase of approximately 16.05%.

During the Reporting Period, in the API segment, Joincare adhered to the management concept of
“green production, cost reduction and efficiency enhancement”, focused on the transformation and
upgrading of production equipment, enhanced the establishment of the quality management system
and strengthened the construction of safety and environmental management, guaranteeing the steady
improvement in the production and yield of key products of the Company. In terms of marketing,
Joincare actively expanded domestic and international markets for the key product 7-ACA by
optimizing strategic cooperation channels and strengthening in-depth cooperation with strategic
customers. Leveraging the advantages in the upstream and downstream industry chains, we
continued to increase our market share. The export share of Meropenem Trihydrate (美罗培南混
粉) has repeatedly set a new high. Despite increased competition in the market this year, the
Company continued to strengthen its position in the market through making plans in advance, thus
the sales and profit of the product hit a historical high. In addition, the Company applied the
registration for Meropenem Trihydrate and Meropenem Crude (美罗培南粗品) in Japanese market
and Italian market, respectively, boosting market development efforts for the products to expand
overseas market share. With the implementation of the centralized procurement of Meropenem for
injection, the Company displayed the advantages of APIs-preparations vertical integration and
actively explored domestic API markets in response to the impacts of centralized procurements.

In terms of API R&D, the Company focuses on two frontier fields to carry out key scientific research.
Firstly, through the transformation and selection systems previously established and in combination
with metabolic engineering, gene editing, systems biology, enzyme directed evolution, high-
throughput screening and other technologies, the Company further optimized conditions for all
processes of genetic modification, gene editing and strains selection. The Company has obtained
more than 450 potential Cephalosporin C (头孢菌, CPC) high-yielding mutant strains from over
65,000 acremonium chrysogenum (产黄支顶孢霉) strains in the initial screening. It obtained 3 new
CPC high-yielding mutant strains for large-scale industrial fermentation through selection, which
made the average CPC yield per unit increased remarkably. Secondly, leveraging on the computer-
assisted protein engineering technology platform and through the omics research, rational
transformation and metabolic regulation on strains, the Company successfully developed screening

                                                 33
Joincare Pharmaceutical Group                                                             Annual Report 2022


strategies on metabolite biosensor applicable to aromatic amino acid and its intermediate products
relying on the optimization of metabolic pathways guided by machine learning. Moreover, the
Company made phased progress in the selection of doramectin, Acarbose, pleocidin, erythrocin,
vitamin B2, levodopa, α-arbutin and other industrial strains and in the improvement of production
process.

③   Health care products and OTC drugs

During the Reporting Period, Joincare (excluding Livzon Group and Livzon MAB) realized
revenues of RMB309 million from health care products and OTC segment, representing a year-on-
year increase of approximately 7.24%.

During the Reporting Period, the Company established a data-driven digital marketing system with
user operation as the core to drive sales growth. On content marketing front, it focused on
strengthening its exposure on social media platforms such as Douyin, RED(小红书) and WeChat,
established cooperative relationships with several professional KOLs and promoted brands and
products through graphics, short videos and livestreaming, to greatly enhance its brand exposure
and at the same time to spread common knowledge on healthcare. In terms of brand marketing, it
jointly unveiled the White Paper on Melasma Prevention and Treatment with industry associations
and professional physicians, carried out common knowledge education and conveyed scientifically-
based health concepts to foster its professional brand image and reputation. In terms of channel sales,
in addition to maintaining the existing sales model of offline channels, we focused on expanding
businesses through online channels such as Tmall, JD.com and Douyin to increase the penetration
rate of channels, thereby boostering brand sales.



 (I) Analysis of principal business
1. Analysis of changes in items of income statement and cash flows statement
                                                                                 Unit: Yuan Currency: RMB
                                                                   Amount for the same
                    Item                   Amount for the period                               Change (%)
                                                                   period of last year
 Revenues                                     17,142,753,068.82      15,903,688,266.59                   7.79
 Operating costs                               6,252,265,308.40        5,716,293,887.58                  9.38
 Selling expenses                              4,950,802,456.16        5,026,812,145.41                 -1.51
 Administrative expenses                         992,483,591.51          939,253,444.33                  5.67
 Financial expenses                             -352,447,424.62          -92,894,751.72                  N/A
 R&D expenses                                  1,742,088,079.94        1,397,131,273.33                 24.69
 Net cash flow from operating
                                               3,977,705,139.29        2,563,089,045.24                 55.19
 activities
 Net cash flow from investing activities       -2,252,167,188.62      -1,964,157,731.17                  N/A
 Net cash flow from financing
                                                 566,122,659.80         -974,904,353.44                  N/A
 activities


                                                      34
   Joincare Pharmaceutical Group                                                            Annual Report 2022


   Reasons for changes in financial expenses: Mainly due to the increase in interest income and the
   increase in foreign exchange gains as a result of exchange rate changes during the Period.

   Reasons for changes in net cash flow from operating activities: Mainly due to the combined effect
   of an increase in sales receipts and a decrease in payment of marketing expenses during the
   Reporting Period.

   Reasons for changes in net cash flow from financing activities: Mainly due to the combined effect
   of new borrowing and investment absorption (through GDR issuance) during the Reporting Period.

   Details of material changes in business type, components or source of profits during the
   current period
   □Applicable √N/A


   2. Analysis of revenues and costs

   √Applicable □N/A
   During the Reporting Period, the Company realized revenues of RMB17,143 million, representing
   a year-on-year increase of 7.79%; the operating costs totaled RMB6,252 million, representing a
   year-on-year increase of 9.38%.


   (1). Composition of principal businesses by industry, product, region and sales model
                                                                                    Unit: Yuan Currency: RMB
                                          Principal business by industry
                                                                               YoY         YoY
                                                                                                      YoY change in
                                                              Gross profit   change in   change in
  By industry         Revenues         Operating costs                                                 gross profit
                                                              margin (%)     revenues    operating
                                                                                                       margin (%)
                                                                                (%)        costs
Pharmaceutical                                                                                       Decreased by
manufacturing      17,005,972,382.14   6,157,580,341.92             63.79         8.03        9.90   0.62 percentage
Industry                                                                                             points
                                                                                                     Decreased by
Service industry        6,761,356.72      2,750,242.27              59.32        34.89       55.02   5.28 percentage
                                                                                                     points
                                          Principal business by product
                                                                               YoY         YoY
                                                                                                      YoY change in
                                                              Gross profit   change in   change in
  By product          Revenues         Operating costs                                                 gross profit
                                                              margin (%)     revenues    operating
                                                                                                       margin (%)
                                                                                (%)        costs
                                                                                                     Increased by
Chemical
                    9,226,385,569.43   1,813,969,087.68             80.34         3.94        3.44   0.09 percentage
pharmaceuticals
                                                                                                     points
Chemical APIs                                                                                        Increased by
and                 5,229,641,907.04   3,409,781,896.55             34.80        11.50        7.06   2.70 percentage
intermediates                                                                                        points
Traditional                                                                                          Decreased by
Chinese             1,296,583,761.24    427,894,665.07              67.00        16.88       44.89   6.38 percentage
medicine                                                                                             points
Diagnostic                                                                                           Decreased by
reagents and         723,535,115.00     352,636,503.06              51.26        -0.05       10.49   4.65 percentage
equipment                                                                                            points
                                                                                                     Decreased by
Biologics            408,488,131.90     106,811,638.64              73.85        80.94     568.08
                                                                                                     19.07 percentage

                                                         35
   Joincare Pharmaceutical Group                                                            Annual Report 2022


                                                                                                     points
                                                                                                     Decreased by
Health care
                     121,235,545.22      46,223,021.02              61.87         5.27       37.35   8.91 percentage
products
                                                                                                     points
                                           Principal business by region
                                                                               YoY         YoY
                                                                                                      YoY change in
                                                              Gross profit   change in   change in
   By region          Revenues         Operating costs                                                 gross profit
                                                              margin (%)     revenues    operating
                                                                                                       margin (%)
                                                                                (%)        costs
                                                                                                     Decreased by
Domestic           14,170,771,017.92   4,326,229,111.25             69.47         7.56       12.73   1.40 percentage
                                                                                                     points
                                                                                                     Increased by
Overseas            2,841,962,720.94   1,834,101,472.94             35.46        10.51        3.80   4.17 percentage
                                                                                                     points

                                        Principal business by sales model

                                                                               YoY         YoY
                                                                                                      YoY change in
                                                              Gross profit   change in   change in
By sales model        Revenues         Operating costs                                                 gross profit
                                                              margin (%)     revenues    operating
                                                                                                       margin (%)
                                                                                (%)        costs
                                                                                                     Decreased by
Channel sales      11,185,248,628.68   2,566,303,271.29             77.06         4.51       11.47   1.43 percentage
                                                                                                     points
                                                                                                     Increased by
Direct sales        5,827,485,110.18   3,594,027,312.90             38.33        15.54        8.83   3.80 percentage
                                                                                                     points

   Note: Biological products include Recombinant SARS-CoV-2 Fusion Protein Vaccine (重组新型

   冠状病毒融合蛋白疫苗), Mouse Nerve Growth Factor for Injection (注射用鼠神经生长因子),

   Bifidobacterium Viable Capsule (双歧杆菌活菌胶囊), Recombinant Human Choriogonadotropin

   alfa for Injection (注射用重组人绒促性素), etc.



   Explanations on composition of principal businesses by industry, product, region and sales
   model

   During the Reporting Period, the Company’s principal businesses generated revenues of
   RMB17,013 million, representing a year-on-year increase of RMB1,266million or 8.04%.

   The growth of the Company’s revenues of principal businesses was primarily due to the Company’s
   continuous efforts in promoting marketing reforms, fully facilitating the mass market product
   channels and accelerating sales in key specialist fields. Sales of main varieties in the key fields of
   chemical pharmaceuticals kept sustained robust growth. In addition, the sales revenues of APIs
   segment grew noticeably with an obvious increase of gross profit margin as the Company taken
   measures to integrate resources, adjust product portfolio, reinforce international certification while
   actively using advanced technologies including synthetic biology and continuous production to
   ensure green production.


   (2). Analysis of production and sales
   √Applicable □N/A


                                                         36
Joincare Pharmaceutical Group                                                                   Annual Report 2022


                                                                                YoY
                                                                                                YoY          YoY change in
     Main                                                   Inventory        change in
                     Unit       Production     Sales                                          change in        Inventory
    products                                                  level          production
                                                                                              sales (%)         (%)
                                                                                (%)
 Ilaprazole      Ten
 sodium for      thousand         1,866.33    1,956.16          225.38            29.94           57.12             -28.71
 injection       boxes
 Leuprorelin
                 Ten
 Acetate
                 thousand          151.98       151.94                 -           -2.39          10.47                     -
 Microspheres
                 ampules
 for Injection
 Ilaprazole
                 Ten
 Enteric-
                 thousand         2,502.09    2,257.23          482.82            28.25            9.82             101.71
 Coated
                 boxes
 Tablets
                 Ten
 Meropenem
                 thousand         1,873.59    2,011.01           13.32             2.59            1.71             -91.16
 for Injection
                 ampules
 7-ACA
 (including D-   Ton              3,065.58    3,018.95          102.50             5.57            1.07                 83.43
 7ACA)


Explanations on production and sales
 In 2022, the Company actively implemented sales planning, stepped up efforts in marketing, and
enhanced specialized and fine sale management, thus leading to significant increase in the output
and sales volume of our major product, Ilaprazole sodium for injection. The change in inventory
was mainly due to the supply and demand at the end of the year and the stock preparation for the
new year.


(3). Performance of major procurement contracts and major sales contracts
□Applicable √N/A


(4). Cost analysis
                                                                                                          Unit: Yuan
                                                                                                   As a
                                                            As a                                percentage
                                                         percentage        Amount incurred        of total
                                   Amount incurred                                                              YoY
                     Cost                                  of total          in the same          costs in
 By industry                        in the current                                                             change
                  components                               costs in           period of          the same
                                        period                                                                  (%)
                                                         the current        previous year        period of
                                                         period (%)                              previous
                                                                                                 year (%)
                 Costs of
                                   3,908,782,585.27           62.52        3,426,827,118.77          59.95      14.06
                 materials
                 Labor costs          809,277,538.94          12.94         619,622,563.47           10.84      30.61
Pharmaceutical
                 Manufacturing
manufacturing                       1,684,532,284.52          26.94        1,487,278,456.52          26.02      13.26
                 costs
Industry
                 Depreciation         406,107,662.76           6.50          322,761,251.80           5.65      25.82
                 Others              -559,185,005.37          -8.94         -141,969,567.28          -2.48       N/A
                 Subtotal           6,249,515,066.13          99.96        5,714,519,823.28          99.97       9.36
Service          Costs of                 512,284.05           0.01              408,782.66           0.01      25.32


                                                       37
      Joincare Pharmaceutical Group                                                                Annual Report 2022


     industry            materials
                         Labor costs           1,757,712.56           0.03          1,022,280.28         0.02     71.94
                         Manufacturing
                                                 327,719.99           0.01           223,280.63          0.00     46.77
                         costs
                         Depreciation            152,525.67           0.00            119,720.73         0.00     27.40
                         Subtotal              2,750,242.27           0.04          1,774,064.30         0.03     55.02
                         Costs of
                                           3,909,294,869.32         62.53    3,427,235,901.43           59.96     14.07
                         materials
                         Labor costs         811,035,251.51         12.97         620,644,843.75        10.86     30.68
                         Manufacturing
     Total                                 1,684,860,004.51         26.95    1,487,501,737.14           26.02     13.27
                         costs
                         Depreciation        406,260,188.43          6.50      322,880,972.53             5.65    25.82
                         Others             -559,185,005.37         -8.94     -141,969,567.28            -2.48     N/A
                         Subtotal          6,252,265,308.40        100.00    5,716,293,887.58          100.00      9.38
                                                                                                      As a
                                                               As a                                percentage
                                                               percentage    Amount incurred         of total
                                         Amount incurred                                                          YoY
                             Cost                              of total      in the same             costs in
       By product                        in the current                                                          change
                          components                           costs in      period of              the same
                                         period                                                                   (%)
                                                               the current   previous year          period of
                                                               period (%)                           previous
                                                                                                    year (%)
                         Costs of
                                              36,089,962.70           0.58         26,560,959.72         0.46     35.88
                         materials
                         Labor costs          11,329,854.63           0.18          6,336,694.50         0.11     78.80
     Health care         Manufacturing
                                               9,444,348.04           0.15          2,677,541.36         0.05    252.72
     products            costs
                         Depreciation          5,463,682.37           0.09          2,564,510.61         0.04    113.05
                         Others              -16,104,826.72          -0.26         -4,487,206.18        -0.08      N/A
                         Subtotal             46,223,021.02           0.74         33,652,500.02         0.59     37.35
                         Costs of
                                           3,841,254,506.51         61.44    3,359,165,272.77           58.76     14.35
                         materials
                         Labor costs         795,400,898.83         12.72         611,624,924.03        10.70     30.05
     Pharmaceutical      Manufacturing
                                           1,620,338,814.98         25.92    1,435,952,937.90           25.12     12.84
     Products            costs
                         Depreciation        400,238,957.27          6.40      320,084,243.85            5.60     25.04
                         Others             -546,139,386.60         -8.74     -157,879,982.96           -2.76      N/A
                         Subtotal          6,111,093,791.00         97.74    5,568,947,395.59           97.42      9.74


      Other information on cost analysis

      Cost and variety of main medicinal herbs used in main TCMs
                   Variety of main                                                  Procurement
 Main TCMs                                        Supply and demand                                    Influence of price fluctuation
                   medicinal herb                                                   model
                                         The supply of Livzon Limin’s
                                         codonopsis root and astragalus root is                        Codonopsis Root: the supply
                                         relatively stable. Both medicinal                             price fall compared with the
Shenqi                                   herbs are supplied by plantation bases     Supplied by        same period last year;
Fuzheng                                  and external suppliers. Plantation         Livzon Limin       Astragalus Root: the supply
                   Codonopsis Root
Injection(参芪                           Base of Livzon Limin Pharmaceutical        Base and           maintained relatively stable,
                   and Astragalus Root
扶正注                                   Manufacturing Factory (“Livzon            external           and the supply price edged up
射液)                                    Limin Base”) maintains safety stock       suppliers          due to the increase in
                                         of medicinal herbs, which ensures the                         processing costs, labor costs
                                         supply quantity and stabilizes the                            and other expenses.
                                         supply price. Meanwhile, Limin


                                                              38
      Joincare Pharmaceutical Group                                                              Annual Report 2022


                                      signed annual demand-based supply
                                      agreements with external suppliers
                                      who are obligated to stock up
                                      according to Limin's quality
                                      requirements, so as to ensure
                                      sufficient supply of herbs with stable
                                      quality.
                                                                                                    For main raw medicinal herbs
                                                                                                    used in Anti-Viral Granules,
                                                                                                    compared with the same
                                                                                                    period of the previous year,
                                                                                                    price of Rehmanniae Radix
                                                                                                    fell largely as the plantation
                                                                                                    area was supplemented
                                                                                                    stimulated by the high price at
                                      There is sufficient supply of main raw
                                                                                                    the earlier stage; price of
                Indigowoad Root,      medicinal herbs used in Anti-Viral
                                                                                                    Radix Curcumae decreased as
                Fructus Forsythiae,   Granules. Indigowoad Root, Acori
Anti-Viral                                                                                          results of expansion of the
                Anemarrhena, Acori    Graminei Rhizome, Anemarrhena,           Tendering
Granules,                                                                                           plantation area; the prices of
                graminei Rhizoma,     Patchouli, Rehmanniae Radix and          procurement,
Anti-Viral                                                                                          some medicinal herbs such as
                Gypsum, Rhizoma       Radix Curcumae are supplied by           supplied by
Granules                                                                                            Indigowoad Root, Fructus
                Phragmitis,           plantation bases and external            plantation base
(Sugar-free),                                                                                       Forsythiae, Rhizoma
                Patchouli,            suppliers; some wild medicinal herbs     and external
Anti-Viral                                                                                          Phragmitis, Patchouli,
                Rehmanniae Radix,     such as Fructus Forsythiae and Acori     suppliers
Syrup, Anti-                                                                                        Anemarrhena, Acori graminei
                Radix Curcumae,       Graminei Rhizome have a certain
Viral Tablets                                                                                       Rhizoma stayed relatively the
                Dahurian Angelica     amount of safety stock to ensure
                                                                                                    same. However, as the
                Root                  basically stable supply and price.
                                                                                                    demand for certain
                                                                                                    varieties of medicinal herbs
                                                                                                    such as Indigowoad Root,
                                                                                                    Fructus Forsythiae, Rhizoma
                                                                                                    Phragmitis and Patchouli
                                                                                                    increased significantly in the
                                                                                                    market at the end of 2022,
                                                                                                    their prices rose to varying
                                                                                                    degrees.



      (5). Changes in consolidation scope due to equity change of major subsidiaries during the
      Reporting Period
      □Applicable √N/A
      (6). Material changes or adjustments in business, products or services during the Reporting
      Period
      □Applicable √N/A
      (7). Major customers of sales and major suppliers
      A. Major customers of sales
      √Applicable □N/A
      Sales to the top 5 customers were RMB1,524.4901 million, representing 8.89% of the total annual
      sales; of which the sales to related parties were RMB0 million, representing 0.00% of the total
      annual sales.
      Sales to any individual customer in excess of 50% of the total, any new customer in the top 5
      customers or heavy dependence on a few customers during the Reporting Period
      □Applicable √N/A

                                                            39
Joincare Pharmaceutical Group                                                           Annual Report 2022


B. Information on major suppliers
√Applicable □ N/A
Purchases from top 5 suppliers were RMB835.906 million, representing 17.24% of the total annual
purchase cost, of which the purchases from related parties were RMB268.667 million, representing
5.54 % of the total annual purchase cost.
Purchases from any individual supplier in excess of 50% of the total, any new supplier in top 5
suppliers or heavy dependence on a few suppliers during the Reporting Period.
□Applicable √N/A
3. Expenses

√Applicable □ N/A
                                                                                                   Unit: Yuan
                                                                         YOY
         Item                   2022                    2021                               Explanations
                                                                       Change(%)
 Selling expenses          4,950,802,456.16      5,026,812,145.41            -1.51   No material change
 Administrative
                            992,483,591.51         939,253,444.33             5.67   No material change
 expenses
                                                                                     Mainly due to the
                                                                                     increase in interest
                                                                                     income and the increase
 Financial expenses        -352,447,424.62            -92,894,751.72          N/A    in foreign exchange
                                                                                     gains as a result of
                                                                                     exchange rate changes
                                                                                     during the Period.
 R&D expenses              1,742,088,079.94      1,397,131,273.33            24.69   No material change


4. Investment in R&D
(1). Investment in R&D
√Applicable □ N/A
                                                                                                   Unit: Yuan
 Current expensed R&D expenditure                                                         1,583,502,138.74
 Current capitalized R&D expenditure                                                        175,159,872.18
 Total R&D expenditure                                                                    1,758,662,010.92
 Total amount R&D expenditure as a percentage of Revenues (%)                                          10.26
 Ratio of capitalized R&D expenditure (%)                                                                 9.96


(2). R&D Staff
√Applicable □ N/A
 Number of R&D staff                                                                                      1,717
 Proportion of R&D staff to the total employees (%)                                                       12.20
                                       Education background of R&D staff
 Education composition                                                                    Number
 PhD                                                                                                        58
 Postgraduate                                                                                              417
 Bachelor                                                                                                  774
 Junior college graduate                                                                                   350


                                                        40
    Joincare Pharmaceutical Group                                                                  Annual Report 2022


     High school and below                                                                                            118
                                              Age composition of R&D staff
     Age composition                                                                                Number
     Under 30 years old (exclusive)                                                                                   842
     30-40 years old (including 30 years old, excluding 40 years old)                                                 640
     40-50 years old (including 40 years old, excluding 50 years old)                                                 187
     50-60 years old (including 50 years old, excluding 60 years old)                                                  48
     Over 60 years old                                                                                                  0


    (3). Explanations
    □Applicable √ N/A

    (4). Reasons for and impact of the material change in the composition of R&D staff
    personnel on future development of the
    Company
    □Applicable √ N/A
    5. Cash flows
    √Applicable □ N/A
                                                                         YOY Change
          Item                   2022                   2021                                         Explanations
                                                                           (%)
                                                                                             Mainly due to the combined
                                                                                             effect of an increase in sales
 Net cash flow from
                             3,977,499,939.73     2,563,089,045.24                 55.19     receipts and a decrease in
 operating activities
                                                                                             payment of marketing expenses
                                                                                             during the Reporting Period.
 Net cash flow from                                              -
                            -2,252,167,188.62                                       N/A      No material change
 investing activities                             1,964,157,731.17
                                                                                             Mainly due to the combined
                                                                                             effect of new borrowing and
 Net cash flow from
                              566,327,859.36       -974,904,353.44                  N/A      investment absorption (through
 financing activities
                                                                                             GDR issuance) during the
                                                                                             Reporting Period.
    (II) Statement on material changes in profits arising from non-principal businesses
    √Applicable □ N/A

                                                                                                                 Unit: Yuan
                                                As a percentage                                                  Sustainable or
           Item                 Amount                                               Cause
                                                 of total profit                                                       not
                                                                   Primarily due to changes in gains or losses
Investment income             55,973,114.29             1.62%                                                         No
                                                                   of the associates.
Gains or losses from                                               Primarily due to fluctuations in market
                             -76,262,989.83            -2.21%                                                         No
changes in fair value                                              value of the securities investment held.
                                                                   Primarily due to the impairment provision
Impairment of assets       -142,627,936.44             -4.13%                                                         No
                                                                   for inventories.
                                                                   Primarily due to income from disposal of
                                                                   scrap and transfer to non-operating income
Non-operating income           8,229,847.57             0.24%                                                         No
                                                                   from buying on credit for longer terms and
                                                                   not required to be paid.
                                                                   Primarily due to donation expenses and
Non-operating expenses        32,060,686.06             0.93%                                                         No
                                                                   loss on retirement of fixed assets.
                                                                   Primarily due to government grants
Other income                 289,868,006.44             8.39%                                                         Yes
                                                                   received.

                                                            41
        Joincare Pharmaceutical Group                                                                  Annual Report 2022




        (III) Analysis of assets and liabilities
        √Applicable □ N/A
        1. Status of assets and liabilities
                                                                                                                   Unit: Yuan
                                                                              The
                                      Proportion                         proportion of
                                       of ending        Ending              ending
                                                                                         Change in
                    Ending balance    balance of       balance of         balance of
      Item                                                                                amount                 Explanations
                     of this period   this period       previous           previous
                                                                                           (%)
                                      to the total       period          period to the
                                      assets (%)                          total assets
                                                                              (%)
                                                                                                      Primarily due to fluctuations in
Financial assets                                                                                      market value of the securities
                     109,015,664.98          0.31    184,638,344.31               0.59       -40.96
held for trading                                                                                      investment held by Livzon Group, a
                                                                                                      subsidiary of the Company.
                                                                                                      Primarily due to the collection of
Other receivables     52,535,740.14          0.15     88,053,825.12               0.28       -40.34   capital reduction proceeds for the
                                                                                                      period.
                                                                                                      Primarily due to the reclassification
Non-current
                                                                                                      of time deposit due within one year
assets due within     54,048,611.11          0.15       317,381.23                0.00    16,929.55
                                                                                                      to non-current assets due within one
one year
                                                                                                      year.
                                                                                                      Primarily due to the increase in cash
Other current                                                                                         management businessof Livzon
                     163,539,900.32          0.46     83,986,214.37               0.27       94.72
assets                                                                                                Group, a subsidiary of the
                                                                                                      Company, for the period.
                                                                                                      Primarily due to the recovery of
Long-term                                                                                             finance lease payments by Livzon
                               0.00          0.00       266,904.13                0.00      -100.00
receivables                                                                                           Group, a subsidiary of the
                                                                                                      Company.
                                                                                                      Primarily due to the fact that the
                                                                                                      “Recombinant SARS-CoV-2 Fusion
                                                                                                      Protein Vaccine (重组新型冠状病
                                                                                                      毒融合蛋白疫苗)” of Livzon MAB
                                                                                                      was included in the emergency use
Intangible assets    802,115,125.75          2.24    456,782,094.80               1.47       75.60    in sequential booster immunization
                                                                                                      against a novel coronavirus SARS-
                                                                                                      CoV-2 in September 2022, and the
                                                                                                      accumulated development
                                                                                                      expenditure of this project was
                                                                                                      transferred to intangible assets.
                                                                                                      Primarily due to the fact that the
                                                                                                      “Recombinant SARS-CoV-2 Fusion
                                                                                                      Protein Vaccine (重组新型冠状病
                                                                                                      毒融合蛋白疫苗)” of Livzon MAB
                                                                                                      was included in the emergency use
Development
                     428,284,884.17          1.20    786,993,435.71               2.53       -45.58   in sequential booster immunization
expenditure
                                                                                                      against a novel coronavirus SARS-
                                                                                                      CoV-2 in September 2022, and the
                                                                                                      accumulated development
                                                                                                      expenditure of this project was
                                                                                                      transferred to intangible assets.
Long-term            277,867,716.95          0.78    200,715,740.93               0.65       38.44    Primarily due to the transfer of


                                                                    42
         Joincare Pharmaceutical Group                                                                   Annual Report 2022


prepaid expenses                                                                                        completion of plant decoration to
                                                                                                        long-term prepaid expenses for the
                                                                                                        period.
                                                                                                        Primarily due to the reclassification
Other non-
                       1,156,772,182.99        3.24    663,584,003.80             2.13          74.32   of time deposit to other non-current
current assets
                                                                                                        assets.
Financial                                                                                               Primarily due to changes in fair
liabilities held for          755,634.43       0.00       143,302.24              0.00        427.30    value of foreign currency forward
trading                                                                                                 contracts.
Non-current                                                                                             Primarily due to the repayment of
liabilities due          63,077,260.98         0.18     91,576,066.33             0.29         -31.12   long-term loans due within one
within one year                                                                                         year.
                                                                                                        Primarily due to the increase in
Other current                                                                                           expected refunds payable of Livzon
                        101,276,714.35         0.28     15,626,224.29             0.05        548.12
liabilities                                                                                             Group, a subsidiary of the
                                                                                                        Company, for the period.
                                                                                                        Primarily due to the newly incurred
Long-term loans        3,230,844,042.88        9.04    826,780,252.78             2.66        290.77    long-term bank borrowings of for
                                                                                                        the period.
                                                                                                        Primarily due to the increase in
Treasury shares         347,176,561.29         0.97    222,644,454.50             0.72          55.93   repurchase of shares to be
                                                                                                        cancelled.

         2. Overseas assets
         √Applicable □ N/A
         (1) Asset size
         Of which: Overseas assets were 42.03 (Unit: 100 million Currency: RMB), representing 11.76 % of
         the total assets.
         (2) Statement on high proportion of overseas assets
         □Applicable √ N/A
         3. Restrictions on assets entitlements as at the end of the Reporting Period
         √Applicable □ N/A
                                                                                                               Unit: Yuan
                                           Carrying value at the
                       Item                                                                  Cause of restriction
                                             end of the period
                                                                         Letters of credit, bank acceptances and forward exchange
           Other monetary funds                         1,392,407.76
                                                                         settlement deposits, etc.
           Notes receivable                           469,659,266.19     Notes pool business and pledge of notes receivable
           Total                                      471,051,673.95



         4. Others
         □Applicable √ N/A
         (IV) Analysis of industry-related business information
         √Applicable □N/A
         According to the Guidelines for the Industry Classification of Listed Companies (2012 Revision)
         issued by the CSRC, the Company is operating in the pharmaceutical manufacturing industry.
         Adhering to the mission of “For the health, For the future” and the vision of “diligently make high-
         quality and innovative drugs”, the Company has been committed to the pharmaceutical business


                                                                    43
Joincare Pharmaceutical Group                                                   Annual Report 2022


and been strengthening R&D, production, marketing and management of medical products, to strive
to become a domestic leading integrated pharmaceutical enterprise with capacity for independent
innovation and international competitiveness in terms of production, technology and management
in the near future.

Analysis of business information on pharmaceutical manufacturing industry
1. Basic information on industry and main drugs (products)
(1). Basic information on industry
√Applicable □N/A

I. Influence of industry policies

The year of 2022 is the second year of the 14th Five-Year Plan, and the pharmaceutical industry is
still magnificent, as opportunities and challenges coexist. Various key programmatic documents and
policies on the pharmaceutical industry have been released, and the major policies that had a
significant impact on the Company are as follows.

① Release of the 14th Five-Year Plan for the Development of the Pharmaceutical Industry

In January 2022, nine departments, including the Ministry of Industry and Information Technology,
the National Development and Reform Commission, jointly issued the “14th Five-Year Plan for the
Development of the Pharmaceutical Industry” (the “Plan”). The Plan clarifies the development goals
for the next five years: by 2025, major economic indicators will achieve medium-high growth,
innovation achievements in frontier fields will be prominent, innovation driving force will be
strengthened, the modernization level of industrial chain will be significantly improved, the supply
and guarantee system of pharmaceutical devices will be further improved, and internationalization
will be advanced in an all-round way. The Plan puts forward goals for the pharmaceutical industry
in terms of scale efficiency, innovation-driven development transformation, industrial chain and
supply chain, drug and equipment supply and international development, it also proposes the
specific development direction of chemical pharmaceuticals, traditional Chinese medicine,
biological medicine and medical device. The pharmaceutical industry is expected to enter into a
new era of sustainable development.

②   Routine operation of volume-based procurement

In July 2022, the Notice on the Results of National Centralized Drug Procurement (GY-YD2022-1)
《关于公布全国药品集中采购(GY-YD2022- 1)中选结果的通知》 was released by the National
Organization Office for Centralized Procurement of Pharmaceuticals. A total of 60 drugs were
successfully procured in this round of centralized procurement, with an average price reduction of
48% for the drugs to be selected. In order to better ensure the stable supply of the drugs for
centralized procurement, the mechanism of "reserve supply enterprises" was introduced in the
procurement documents initially for the seventh batch of centralized drug procurement, to explore
the implementation of "double supply in one province", each province not only has a selected


                                                 44
Joincare Pharmaceutical Group                                                     Annual Report 2022


enterprise, that is, the main supply enterprise, but also has a reserve supply enterprise.

③   Adjustment of the catalog of medicines covered by medical insurance

In June 2022, the NHSA issued the 2022 Work Plan of the Adjustment to the Catalogue of Drugs
for National Basic Medical Insurance, Work-related Injury Insurance and Maternity Insurance
(《2022 年国家基本医疗保险、工伤保险和生育保险药品目录调整工作方案》) and related
documents for public comments, marking commencement of a new round of adjustment work for
the National Medical Insurance Catalogue. The adjustment work for the Medical Insurance
Catalogue has been continuously improved and has entered the era of dynamic adjustment. While
continuing to support COVID-19 treatment drugs and innovative drugs, the new medical adjustment
plan issued in June 2022 fully reflects the attention to treatment drugs for rare disease and drugs for
children. In September 2022, the NHSA issued the 2022 National Medical Insurance Catalogue
Adjustment through Initial Review of Drugs and Information (2022 年国家医保药品目录调整通
过初步形式审查药品及信息), with 344 varieties shortlisted.

④   New Notice of reform of DRG/DIP payment method

In April 2022, the NHSA issued the Notice on the Convergence of the Use of DRG/DIP Functional
Module of the Payment Method Management Subsystem (《关于做好支付方式管理子系统
DRG/DIP功能模块使用衔接工作的通知》), which clarified that the NHSA had developed the
basic version of the DRG/DIP functional module based on the nationally unified medical insurance
information platform, and would promote the DRG/DIP payment method reform to a deeper level.
According to the arrangement, the DRG/DIP functional module would be implemented and applied
nationwide by the end of November 2022.

⑤   Promoting innovation in traditional Chinese medicine

In March 2022, the General Office of the State Council issued the 14th Five-Year Plan for the
Development of Traditional Chinese Medicine (《“十四五”中医药发展规划》) , which specifies
the guiding ideology, basic principles and development goals for the development of TCM during
the 14th Five-Year Plan period, proposes 10 major tasks and 11 work columns, and specific
measures for each of the major tasks. By 2025, the capacity of TCM health services will be
significantly enhanced, the policy and system for high-quality development of TCM will be further
improved, positive results will be achieved in the revitalization and development of TCM, and its
unique advantages in the construction of a healthy China will be given full play.

In December 2022, the National Administration of Traditional Chinese Medicine issued the 14th
Five-ear Plan for the Development of Traditional Chinese Medicine Informatization (《“十四五”
中医药信息化发展规划》), which clearly proposed the construction of TCM internet hospitals, the
development of telemedicine and internet diagnosis and treatment, and providing support for the
construction of intelligent hospitals in about 20 Class III TCM hospitals. Meanwhile, governments
at various levels actively support the development of TCM informatization through existing funding

                                                  45
Joincare Pharmaceutical Group                                                     Annual Report 2022


channels, and through guiding social investment to increase investment in TCM informatization and
statistics.

⑥    In-depth reform of medical and healthcare system

In May 2022, the General Office of the State Council issued the Key Tasks for Deepening the
Reform of the Medical and Health System in 2022 (《深化医药卫生体制改革2022年重点工作任
务》)(the "Tasks"), which put forward 21 key tasks from 4 aspects covering accelerating the
construction of a new pattern of orderly access to medical diagnosis and treatment, deeply
promoting the experience of Sanming's medical reform, making efforts to enhance the capacity of
public health services, and promoting the high-quality development of medicine and health. The
general requirements of the Tasks are to comprehensively promote the construction of a healthy
China, deeply promote the experience of Sanming's medical reform, promote the expansion and
balanced layout of high-quality medical resources, deepen the linkage reform of medical care,
medical insurance and medicine, continuously promote the shift from focusing on the treatment to
focusing on people's health, and continuously promote to solve the difficult problems of the lack of
accessibililty to and the high costs of medical treatment. For the pharmaceutical industry, new
requirements for development at stages have also been put forward.

⑦    Market exclusivity of new drugs for rare diseases

In May 2022, the NMPA conducted a study on the Implementation Rules of the Law of the PRC on
the Administration of Drugs (《中华人民共和国药品管理法实施条例》),forming an amended
consultation draft for public comments (the “Consultation Draft"). The Consultation Draft proposes
for the first time to grant a period of market exclusivity to new drugs such as drugs for rare diseases.
The Consultation Draft proposes that the state encourages the development and innovation of drugs
for rare diseases, supports the development of drugs for rare diseases by the holders of drug
marketing licenses, encourages the development of launched drugs for new indications of rare
diseases, and gives priority to the review and approval of drugs for rare diseases that are in urgent
clinical need. During drug development and registration filing, communication with sponsors will
be strengthened to facilitate the speedy launch of drugs for rare diseases and meet the clinical needs
of patients with rare diseases. For new drugs approved for marketing for rare diseases, a period of
market exclusivity of up to seven years will be granted under the commitment of the drug's
marketing licensee to safeguard the supply of the drug, during which time the same variety will not
be approved for marketing.

Response measures: The Company will take effective measures to cope with major changes in
policies of the pharmaceutical industry through early layout, transformation, and compliance, and
constantly improve its core competitive strength. Meanwhile, the Company will actively increase
the research, development and innovation of new products, drive development through R&D,
continuously optimize and adjust the product structure, strenuously apply for medical insurance


                                                  46
Joincare Pharmaceutical Group                                                     Annual Report 2022


coverage, and maintain the competitive sales of large varieties while keeping striving for market
access and promoting sales to lower-tier markets. The Company will create more competitive
advantages of products, improve the production quality management, standardize the safe and
environmentally friendly production, operate in compliance with regulations, and establish a more
reasonable market-oriented system in order to establish its own advantageous position and core
competitiveness.

II. Basic information on the sector where the Company operates

The Company is primarily engaged in the R&D, production and sale of hundreds of varieties of
pharmaceutical products and health care products in areas such as chemical pharmaceuticals,
biologics, chemical active pharmaceutical ingredients (APIs), TCM, and health care products. Basic
information on the market niches in which the Company operates are follows:

Chemical pharmaceuticals: In recent years, influenced by policies regarding medical insurance
payment control, volume-based procurement and consistency evaluation, chemical pharmaceuticals
have recorded a slower growth in revenues and profit. The market of chemical pharmaceuticals is
relatively competitive as there are many domestic manufacturers. However, innovative drugs and
high-barrier formulations will become an industry trend and an important source of profits thanks
to low competitive pressure and continuous support from national policies. The Company's
chemical pharmaceuticals cover many therapeutic fields with competitive strengths in product
varieties, sales channels, end user groups and brand awareness. In the future, the Company will
speed up research and development, introduce new technologies, and accelerate the product
structure optimization and strategic planning to cope with the increasingly fierce market competition.

Biologics: Biologics include monoclonal antibodies, vaccines, recombinant therapeutic proteins and
other biological therapies. Globally, the development of biologics has been relatively late compared
to chemical pharmaceuticals products, and it is only in the last 40 years that they have entered the
large-scale industrialization stage. However, due to the safety, efficacy, and other clinical needs met
by biologics that chemical pharmaceuticals could not satisfy, the biologics industry has grown
rapidly in recent years, especially in emerging markets such as China, where the biologics industry
is growing at a much faster rate than the general pharmaceutical industry. China's biologics market
is still in a period of unstable segment structure, continued increase in unmet clinical needs, more
frequent technology iteration, and rapid growth of emerging segments such as monoclonal
antibodies. LivzonBio is the primary biopharmaceutical R&D platform of the Company and
principally engages in the independent innovative R&D and commercialization of
biopharmaceuticals, including innovative mAbs (monoclonal antibodies), mAb biosimilars,
bispecific antibodies, antibody drug conjugates, CAR-T cell therapies, etc., with its products
covering multiple fields such as tumor, autoimmune disease, vaccine, etc.

Chemical APIs: At present, the Company has the following chemical APIs: cephalosporin series,


                                                  47
Joincare Pharmaceutical Group                                                    Annual Report 2022


statin series, and carbapenem series among others. Restricted by heavy investment, long
construction period, high technical threshold and strict environmental protection requirements, the
bulk API market in China is relatively concentrated. However, overcapacity causes fierce
competition. To adapt to future competition, the Company gradually completed the transformation
and upgrading from bulk APIs to high-end characteristic APIs, from nonstandard market to
standardized market and from domestic market to international market. Meanwhile, in an effort to
further implement the Implementation Plan to Promote the High-quality Development of the API
Industry issued by the National Development and Reform Commission and the Ministry of Industry
and Information Technology in November 2021, the Company strengthened forward-looking
research layout to accelerate high-quality development of APIs under new background. Since
October 2020, the Company has focused on building a research and development platform in
synthetic biology with AI integrated to promote green, low-carbon transformation of the industry,
to give more added value to pharmaceutical intermediates and APIs, and to accelerate integration
into the global industrial chain and value chain.

TCM: In recent years, encouraged by many favorable national policies, the TCM industry has
gained abundant opportunities to grow. Since 2021, the state has successively issued several policies,
including the Several Policies and Measures on Accelerating the Characteristic Development of
Traditional Chinese Medicine, the Notice on Updating the Classification and Codes of Diseases and
Patterns of Traditional Chinese Medicine (Covered by Medical Insurance) and the14th Five-Year
Plan for the Development of Traditional Chinese Medicine. These policies emphasize the need to
optimize the TCM evaluation and approval management, to improve the classification and
registration management, to implement suitable payment policies, to strengthen the price
management, to adopt integrative medicine approach, and to promote the development of TCM
industry. In the fight against the epidemic, ‘three drugs and three prescriptions’ of TCM play an
important role in clinic treatment, highlighting the importance of TCM. Shenqi Fuzheng Injection,
Anti-Viral Granules and other products from Livzon Group, a holding subsidiary of the Company,
are representatives of the Company's TCM products. In the future, the Company will continue to
intensify R&D and technological innovation to drive sustainable profitability.

Diagnostic reagents and equipment: As China's healthcare industry develops gradually, in vitro
diagnostic reagents industry is seeing a bigger market but remains in primary stage compared with
developed countries such as European countries and America. With more product varieties and more
advanced technologies, in vitro diagnostic reagents are used in more scenarios, from traditional
hospital laboratories to third-party medical diagnostic institutions, physical examination centers,
families, and other primary healthcare institutions. More application scenarios make the demand for
different kinds of in vitro diagnostic reagents fully released, promoting rapid development of the
industry. Since its establishment, Livzon Diagnostics, controlled by Livzon Group (a holding
subsidiary of the Company), has been committed to the R&D, production and sales of diagnostic
reagents and equipment. After years of efforts and development, it has built a multi-faceted technical

                                                    48
              Joincare Pharmaceutical Group                                                                                        Annual Report 2022


              platform that supports ELISA test, colloidal gold rapid test, chemiluminescence assay, multiplex
              liquid-chip assay, and nucleic acid assay. It has strong market influence in such fields as respiratory
              infection, infectious diseases, and drug concentration monitoring. Some of its products hold big
              market shares in China.

              Health care products: Driven by increasing public awareness of wellness, aging, consumption
              upgrading and promotion of direct sales, health care industry has developed rapidly in recent years.
              However, due to low technical threshold and high gross profit, the domestic market is highly
              competitive with serious product homogeneity issues and low market concentration. The
              Company’s well-known health care foods brands such as “Taita” (太太),“ Jingxin” (静心) and
              “Eagle's” (鹰牌) deeply rooted in people's minds and have high market awareness. Faced with
              intense market competition, while staying committed to traditional pharmaceutical chain channels,
              the Company also actively expands online channels through strategic cooperation with new social
              e-commerce sales platforms to drive sales growth. In addition, the Company actively prepares to
              access to fields of functional food by leveraging its R&D and market strengths to enrich product
              pipelines and enhance core competitiveness.


                (2). Basic information on main drugs (products)
              √Applicable □N/A
              Basic information on main drugs (products) by segment and therapeutic areas
              √Applicable □N/A
                                                                                                                                                       Included
                                                                                                                                          New drug
                                                                                                                         Effective and                  in the
                                                                                                                                          (product)
                                                                                                           Protected      expiration                   Catalog     Included
                       Main            Name of                                                                                            launched
                                                     Registration                           Prescription     TCM         date of patent                   of          in
   Segment          therapeutic          drug                         Indications                                                         during the
                                                         Category                           drug or not     or not (if     right for                   National     NRDL
                        area          (product)                                                                                           Reporting
                                                                                                           applicable)   invention (if                 Essential    or not
                                                                                                                                          Period or
                                                                                                                          applicable)                  Drugs or
                                                                                                                                             not
                                                                                                                                                         not
                                                                                                                         From 23
                                     Ilaprazole      Chemical
Chemical                                                            Peptic ulcer                                         October
                  Gastroenterology   Sodium for      drugs Class                                Yes            No                            No           No         No
pharmaceuticals                                                     bleeding                                             2009 to 23
                                     Injection       2
                                                                                                                         October 2029
                                                                                                                         From 23
                                     Leuprorelin                    Endometriosis,
                                                     Chemical                                                            December
Chemical          Gonadotropic       Acetate                        hysteromyoma,
                                                     drugs Class                                Yes            No        2010 to 23          No           No         Yes
pharmaceuticals   hormones           Microspheres                   breast cancer,
                                                     6                                                                   December
                                     for Injection                  etc.
                                                                                                                         2030
                                     Ilaprazole                                                                          From 24
                                                     Chemical       Duodenal ulcer
Chemical                             Enteric-                                                                            March 2006 to
                  Gastroenterology                   drugs          and reflux                  Yes            No                            No           No         Yes
pharmaceuticals                      Coated                                                                              24 March
                                                     Class 1.1      esophagitis
                                     Tablets                                                                             2026
                                                                    Used to treat
                                                                    infection caused                                     From 6 June
                                                     Chemical       by one                                               2006 to 6 June
Chemical                             Meropenem
                  Anti-infection                     drugs Class    bacterium                   Yes            No        2026 From 31        No           No         Yes
pharmaceuticals                      for Injection
                                                     4              or more bacteria                                     July 2012 to
                                                                    sensitive to                                         31 July 2032
                                                                    meropenem.

              Note: The starting and expiration dates listed above refer to the corresponding term of patents of
              core products in each product category.




                                                                                       49
  Joincare Pharmaceutical Group                                                                 Annual Report 2022


  Main drugs (products) newly added into and exited from the National Reimbursement Drug
  List during the Reporting Period
  √Applicable □N/A
                                             Catalog of National Essential        National Reimbursement Drug
         Name of main products
                                                          Drugs                                     List
    Ilaprazole Sodium for Injection                    Not included                            Included
    Leuprorelin Acetate Microspheres                   Not included                            Included
    for Injection
    Ilaprazole Enteric-Coated Tablets                  Not included                            Included
    Meropenem for Injection                            Not included                            Included


  Winning bids for main drugs in centralized drug procurement during the Reporting Period
  √Applicable □N/A
                                                                                Total actual
                                                                                procurement
            Name of main drugs                      Bid-winning price range       volume by                    Unit
                                                                                   medical
                                                                                 institutions
Ilaprazole Sodium for Injection                                   RMB71.00             1,697.62       Ten thousand boxes
Leuprorelin Acetate Microspheres for
                                                      RMB1,272.58-1,275.90                 153.70     Ten thousand ampules
Injection
Ilaprazole Enteric-Coated Tablets (6 tablets)             RMB78.34-99.58               1,490.93       Ten thousand boxes
Ilaprazole Enteric-Coated Tablets (10 tablets)           RMB156.30-158.12                118.60       Ten thousand boxes
Meropenem for Injection 0.25g                              RMB6.30-54.66                 638.23       Ten thousand ampules
Meropenem for Injection 0.5g                              RMB10.71-86.53               1,178.07       Ten thousand ampules
Meropenem for Injection 1g                                 RMB18.21-167                   73.49       Ten thousand ampules


  Explanations
  √Applicable □N/A
  ① Data regarding total actual procurement volume by medical institutions are from IQVIA;
  ② The information disclosed is the bid-winning price of the issuer province and newly
      implemented winning prices during the Reporting Period.
  ③ Meropenem for Injection was included in the seventh batch of national volume-based drug
      procurement in July 2022, with a significant price adjustment.

  Operating data by therapeutic areas or main drug (products)
  √Applicable □N/A
                                                           Unit: 10,000 Yuan Currency: RMB
                                                                    YoY                        YoY
                                                                                 YoY                         Gross profit
                                                      Gross        change                     change
                                                                                change                        margin of
                       Operating      Operating       profit          in                     in gross
 Therapeutic area                                                                  in                       products in the
                        income          costs         margin      operating                    profit
                                                                               operating                   same field in the
                                                       (%)         income                     margin
                                                                               costs (%)                    same industry
                                                                     (%)                        (%)
Gastroenterology       343,589.84       47,011.06       86.32          -6.48        5.00         -1.50                79.23
Gonadotropic
                       259,068.36       82,191.10       68.27           5.64       -4.66            3.43                   -
hormones
Anti-infection         130,468.34       24,765.24       81.02         -16.44       -2.24        -2.76                 58.39
Respiratory            117,364.29       20,014.56       82.95         103.37       87.69         1.43                 84.95
Psychiatry              54,484.55        2,845.42       94.78          32.19       44.07        -0.43                 82.92


                                                            50
Joincare Pharmaceutical Group                                                   Annual Report 2022




Explanations
√Applicable □N/A
① The gross profit margin of products in the field of gastroenterology is derived from that of the
   relevant industry in “Major products of metabolism and alimentary system” in Fosun Pharma's
   2021 Annual Report.
②    No comparable data on gross profit margin in the field of gonadotropic hormones has been
     found.
③    The data on the gross profit margin of products in the field of anti-infection comes from that
     of “anti-infection category” in the 2021 Annual Report of Tianyao Co., Ltd.
④     The gross profit margin data of products in the field of the respiratory comes from that of
     “respiratory system category” in Luoxin Pharmaceutical's 2021 Annual Report.
⑤ The gross profit margin data of products in the psychiatric field comes from that of “psychiatric
   category” in Nhwa Pharmaceutical 's 2021 Annual Report.

2. Drug (product) R&D of the Company
(1). Overview of R&D of the Company
√Applicable □N/A

(1)Chemical pharmaceuticals

① High-barrier complex formulations: There were a total of 45 projects under research, of which,
4 had been launched to the market, 6 had been applied for production, 11 were under the clinical/BE
study and 2 received clinical trial approvals. The progress of the major projects was as follows:

Inhalation formulations: Terbutaline Sulfate Nebulizer Solution (硫酸特布他林雾化吸入用溶
液) and Levosalbutamol Hydrochloride Nebulizer Solution (盐酸左沙丁胺醇雾化吸入溶液)
(3ml:1.25mg), Acetylcysteine solution for inhalation(吸入用乙酰半胱氨酸溶液) and Tobramycin
Inhalation Solution (妥布霉素吸入溶液) had been launched for market. Fluticasone Propionate
Inhalation Suspension (丙酸氟替卡松雾化吸入用混悬液) had been applied for production; The
clinical trial of Indacaterol Maleate Powder for Inhalation (马来酸茚达特罗吸入粉雾剂) had been
completed and the drug had been applied for production; The registration application of Salmeterol
Xinafoate -Fluticasone Propionate Powder for Inhalation (沙美特罗替卡松吸入粉雾剂) was
submitted after the completed PK-BE study, the notice of clinical trial approval was received, and
the phase III clinical study was quickly started; Phase I clinical trials of Levosalbutamol
Hydrochloride and Ipratropium Bromide Inhalation Solution (盐酸左沙丁胺醇异丙托吸入溶液)
and Formoterol Fumarate Inhalation Aerosol (富马酸福莫特罗吸入气雾剂) were completed; For
class 2 new drug XYP-001, the Company had received the notice of the clinical trial approval and
started phase I clinical trials;

Sustained-release microspheres: The project of Triptorelin Acetate Microspheres for Injection (注
射 用 醋 酸 曲 普 瑞 林 微 球 ) (1-month sustained release) for treatment of prostate cancer had
completed all registration verification, GMP compliance checks, the first registration inspection,


                                                 51
Joincare Pharmaceutical Group                                                        Annual Report 2022


and the supplementary data studywhich was submitted to CDE; the project of Triptorelin Acetate
Microspheres for Injection (注射用醋酸曲普瑞林微球) (1-month sustained release) for treatment
of endometriosis has completed patient enrollment, the follow-up period close to end; Aripiprazole
Microspheres for Injection (注射用阿立哌唑微球) (1-month sustained release) completed phase I
multiple-dosing clinical trial; Octreotide Acetate Microspheres for Injection (注射用醋酸奥曲肽
微球) (1-month sustained release) and Leuprorelin Acetate Microspheres for Injection (注射用醋
酸亮丙瑞林微球) (3-month sustained release) were undergoing BE trials; Alarelin Microspheres
for Injection (注射用丙氨瑞林微球) (1-month sustained release) was undergoing phase I clinical
trial; Triptorelin Pamoate Microspheres for Injection (注射用双羟萘酸曲普瑞林微球) (3-month
sustained release) was in phase I clinical trial; Triptorelin microspheres of dihydroxynaphthoate for
injection (3-month sustained release) was prepared for phase I clinical trial; Goserelin Acetate
Sustained-release Implant (醋酸戈舍瑞林缓释植入剂) (1-month sustained-release) had carried out
the bridging study of pilot-scale and full-scale production.

②Conventional formulations: There were a total of 42 projects under research, of which, 6
projects had applied for production, 5 projects were under the clinical/BE study and 3 projects
received clinical trial approval. The progress of the major projects was as follows: New indications
of Ilaprazole Sodium for injection (注射用艾普拉唑钠), Blonanserin Tablets(布南色林片) and
Lurasidone Hydrochloride Tablets (盐酸鲁拉西酮片) had been applied for production; LZ001 and
Ilaprazole Enteric-coated Tablets(艾普拉唑微丸肠溶片) have been approved for phase I clinical
trials; and Progesterone Injection(黄体酮注射液) was undergoing BE trial.

③Consistency evaluation: There were a total of 16 projects under research, of which, 6 projects
have been approved for launching and 3 projects applied for review. 6 varieties such as
Clarithromycin Tablets(克拉霉素片), Valsartan Capsules(缬沙坦胶囊), and Cefodizime Sodium
for Injection (注射用头孢地嗪钠) had been approved for launching; Supplemental information had
been submitted for Imipenem and Cilastatin Sodium( 亚 胺 培 南 西 司 他 丁 钠 ), Cyclosporine
Softgels(环孢素软胶囊) (50 mg), Vancomycin Hydrochloride for Injection and Bismuth Potassium
Citrate Capsule (枸橼酸铋钾胶囊).

(2)Biologics

There were a total of 8 projects under research, of which, 1 was approved for launching, 1 in the
conditional marketing application stage; 1 in the marketing application (BLA) stage (approved for
marketing in January 2023), 1 in the phase III clinical trial, 2 in the phase Ib or phase II clinical trial
and 2 in the phase I clinical trial.

Therapeutic biological products: Recombinant Human Choriogonadotropin Alfa for injection was
approved for launching in China in 2021 and overseas registration is underway; the BLA application of
Tocilizumab injection (托珠单抗注射液) has been accepted by CDE and approved for launching in
China in January 2023; phase II clinical trials of Recombinant Anti-human IL-17A/F Humanized


                                                    52
Joincare Pharmaceutical Group                                                       Annual Report 2022


Monoclonal Antibody for Injection (重组抗人 IL-17A/F 人源化单克隆抗体注射液)were completed;
Recombinant Humanized Anti-PD-1 Monoclonal Antibody for Injection (注射用重组人源化抗 PD-1
单 克 隆 抗 体 ) is undergoing phase Ib/II clinical trials; Recombinant Human Follicle Stimulating
Hormone for Injection (重组人促卵泡激素注射液) completed Phase I clinical trials; and Recombinant
Tumor Enzyme Specific Interferon α-2bFc Fusion Protein for Injection (注射用重组肿瘤酶特异性干
扰素 α-2bFc 融合蛋白) was undergoing phase I clinical trials. The diabetic drug Semaglutide injection
(司美格鲁肽注射液) was approved for clinical trials, and the first phase III clinical center was launched
in December 2022.

Preventive biological products: The Recombinant SARS-CoV-2 Fusion Protein Vaccine (Likang V-01)
was approved for emergency use in domestic heterologous booster vaccination in June 2022, and was
included in the national immunization program in September 2022. Meanwhile, a conditional marketing
application of such vaccine had been submitted to the NMPA, which was under review.

(3)APIs and intermediates

There were a total of 39 projects under research, of which 23 were new product R&D projects and
16 were tech-upgradation projects of existing products. For new product R&D projects, the API of
Fluticasone Furoate ( 糠 酸 氟 替 卡 松 ) had been approved for launching, and the registration
application for the API of Biapenem(比阿培南) and the API of Caspofungin Acetate (醋酸卡泊芬
净)were submitted. For technological upgrading projects of existing products, the key project
Cephalosporin C-High Producing Mutant Strains (头孢菌素 C 高产突变株) was progressing
smoothly. After screening, the scale production verification of the strains had been completed, and
the average unit yield had been steadily increased; in the development and selection project of new
L-phenylalanine – High Producing Strains (L-苯丙氨酸新型高产菌株) driven by IBT technology,
high-value natural product chassis strains such as L-phenylalanine, L-tyrosine and shikimic acid
had been screened, strain modification and selection was proceeding and shake-flask cultivation has
achieved initial results.

(4)Traditional Chinese medicine

There were 8 projects under research for new TCM, of which, SXSHL gel, a new improved
traditional Chinese medicine, had completed pre-clinical trial experiment research, and its
application materials were being prepared and collected. The single-center clinical trial of in-
hospital preparations was completed for TGDX Granules, a class 1.1 new traditional Chinese
medicine, and initial draft of the clinical trial summary report was obtained.

(5)Diagnostic reagents and equipment

There were 86 projects under research, of which, 1 was in the clinical stage (including evaluation); there
were a total of 15 technological upgradation projects, including 7 projects were filed for change of
registration. In March 2022, Livzon Diagnostics actively responded to the national pandemic prevention
and control policy, and promptly initiated the registration of Livzon Rapid Test for 2019-nCoV Antigen

                                                   53
          Joincare Pharmaceutical Group                                                                   Annual Report 2022


          (Lateral Flow) (新型冠状病毒 (2019-nCoV)抗原检测试剂盒(乳胶法)), which was successfully
          approved for launching on April 9, 2022. Diagnostic Kit for Immunoglobulin G4 (Chemiluminescence
          Immunoassay) (免疫球蛋白 G4 测定试剂盒(化学发光法)) and its supporting calibrators and quality
          control products obtained registration certificates in June 2022; mycoplasma pneumoniae IgM antibody
          detection kit (chemiluminescence) and four diabetes specific autoantibodies were registered successively
          in November 2022; three items of chromatography platform blood type card were registered in August
          2022. In addition, 6 projects, including Livzon Rapid Test for 2019-nCoV Antigen (Lateral Flow) (新型
          冠状病毒(2019-nCoV)抗原检测试剂盒(乳胶法)) and Nucleic Acid Test Kit for Monkeypox Virus
          (Real-time PCR) ( 猴 痘 病 毒 核 酸 检 测 试 剂 盒 (PCR- 荧 光 探 针 法 )), and full automated
          chemiluminescence analyzer successively obtained CE certificates.



          (2). Basic information on main R&D projects
          √Applicable □N/A
                                                                                                               Protected
    R&D projects
                          Name of drug       Registration                                      Prescription   TCM or not     R&D stage
 (including projects                                                   Indications
                           (product)          Category                                         drug or not        (if       (registration)
   subject to GCE)
                                                                                                              applicable)
                                                            It is suitable for maintenance
                                                            therapy of bronchiectasis to
Indacaterol Maleate    Indacaterol Maleate   Chemical       relieve symptoms in adults with                                 Application
Powder for             Powder for            drugs Class    chronic obstructive pulmonary          Yes            No        for
Inhalation             Inhalation            4              disease (COPD), including                                       registration
                                                            chronic bronchitis and
                                                            emphysema.
Fluticasone            Fluticasone
                                             Chemical                                                                       Application
Propionate             Propionate                           Treatment of moderate and
                                             drugs Class                                           Yes            No        for
Inhalation             Inhalation                           severe persistent asthma.
                                             4                                                                              registration
Suspension             Suspension
                                                            Suitable for the maintenance
                                                            treatment of bronchoconstriction
Formoterol             Formoterol            Chemical                                                                       Application
                                                            in patients with chronic
Fumarate Inhalation    Fumarate Inhalation   drugs Class                                           Yes            No        for
                                                            obstructive pulmonary disease
Solution               Solution              3                                                                              registration
                                                            (COPD), including chronic
                                                            bronchitis and emphysema.
                                                            In combination (bronchodilators
Salmeterol             Salmeterol
                                                            and inhaled corticosteroids) for
Xinafoate and          Xinafoate and         Chemical
                                                            the regular treatment of
Fluticasone            Fluticasone           drugs Class                                           Yes            No        Clinical trial
                                                            reversible obstructive airways
Propionate Powder      Propionate Powder     4
                                                            disease, including asthma in
for Inhalation         for Inhalation
                                                            adults and children.
                                             Chemical
                                             drugs Class    For the treatment of Idiopathic
XYP-001                XYP-001                                                                     Yes            No        Clinical trial
                                             2.2; Class     pulmonary fibrosis (IPF)
                                             2.4
Mometasone             Mometasone
Furoate and            Furoate and           Chemical       Suitable for bronchial asthma
Formoterol             Formoterol            drugs Class    and chronic obstructive                Yes            No        Clinical trial
Fumarate Dihydrate     Fumarate Dihydrate    3              pulmonary disease.
Inhalation Aerosol     Inhalation Aerosol




                                                                     54
          Joincare Pharmaceutical Group                                                                         Annual Report 2022


Formoterol               Formoterol            Chemical       Suitable for bronchial asthma
Fumarate Inhalation      Fumarate              drugs Class    and chronic obstructive                  Yes            No           Clinical trial
Aerosol                  Inhalation Aerosol    2.2            pulmonary disease.
                         Recombinant Novel     Preventive
                         Coronavirus Fusion    biological     Prevention of diseases caused by                                     Launched
V-01(COVID-19)                                                                                       Yes            No
                         Protein Vaccine       product        novel coronavirus infection                                          under EUA
                                               (Class 1.1)
                         Recombinant
                         Humanized   Anti-     Therapeutic                                                                         Application
LZM009(PD-1)           PD-1 Monoclonal       biological     Advanced solid tumors                    Yes            No           for
                         Antibody     For      product                                                                             registration
                         Injection
Triptorelin acetate                                           Metastatic prostate cancer,
sustained-release        Triptorelin Acetate   Chemical       endometriosis (stage I to IV),                                       Application
microspheres      for    Microspheres    for   drugs Class    female infertility, preoperative         Yes            No           for
injection (1 month       Injection             2.2            treatment of uterine fibroids,                                       registration
release)                                                      precocious puberty
                         Recombinant Anti-
                         Human     IL-17A/F    Therapeutic
LZM012        (   IL-   Humanized             biological     Moderate to severe plaque
                                                                                                       Yes            No           Clinical trial
17A/F)                  Monoclonal            product        psoriasis
                         Antibody        for   (Class 1)
                         Injection
                                               Chemical                                                                            Application
Blonanserin              Blonanserin           drugs Class    Schizophrenia                            Yes            No           for
                                               4                                                                                   registration


          (3). Drugs (products) filed for regulatory approval and granted approval during the
          Reporting Period
          √Applicable □N/A

          ①       Drugs (products) filed for regulatory approval during the Reporting Period
                                       Registration
              Name of drug                              Approval items                                 Indications
                                         Category
     Fluticasone Propionate            Chemical         Application for        Treatment of mild to moderate acute asthma attacks in
     Nebulized Suspension              drugs Class 4    registration           children and adolescents aged 4-16 years.
                                                                               This product is a bronchodilator suitable for maintenance
     Indacaterol maleate               Chemical         Application for
                                                                               treatment of adult patients with chronic obstructive
     inhalation powder                 drugs Class 4    registration
                                                                               pulmonary disease (COPD).
     Triptorelin Acetate
                                       Chemical
     Microspheres for                                   Application for
                                       drugs Class                             Prevent stress ulcer bleeding in severe patients.
     Injection (new                                     registration
                                       2.4
     indications)
                                       Chemical         Application for
     Blonanserin Tablets                                                       Schizophrenia.
                                       drugs Class 4    registration
     Lurasidone Hydrochloride          Chemical         Application for
                                                                               Schizophrenia.
     Tablets                           drugs Class 4    registration
                                                                               Used for routine treatment of reversible obstructive
     Salmeterol Xinafoate and
                                       Chemical         Application for        airway diseases through combination of drugs
     Fluticasone Propionate
                                       drugs Class 4    Clinical trials        (bronchodilators and inhaled corticosteroids), including
     Powder for Inhalation
                                                                               asthma in adults and children.


                                                                          55
    Joincare Pharmaceutical Group                                                                       Annual Report 2022


                                Chemical
                                                 Application for
XYP-001                         drugs Class                             Temporarily used for idiopathic pulmonary fibrosis
                                                 Clinical trials
                                2.2 and 2.4
Recombinant Novel
Coronavirus Fusion              Preventive
Protein Bivalent                Biological       Application for        Used for treatment of novel coronavirus infection
(prototype strain/Omicron       products         Clinical trial         (COVID-19).
strain) Vaccine (CHO            Class 1.1
cells)
                                Chemical         Application for        Luteal function supplementation in infertile women
Progesterone Injection
                                drugs Class 3    Clinical trials        undergoing assisted reproductive technology.
                                                                        1. Treat duodenal ulcer and reflux esophagitis.2.
                                                                        Treatment of duodenal ulcer and reflux esophagitis in
                                Chemical
Ilaprazole enteric-coated                        Application for        children (12-17 years old).3. Treat non-erosive
                                drugs Class
pellets                                          Clinical trials        gastroesophageal reflux disease.4. Treat gastric ulcer.5.
                                2.2 and 2.4
                                                                        Eradication of helicobacter pylori.6. Prevent gastric ulcer
                                                                        caused by non-steroidal anti-inflammatory drugs.
                                Chemical
                                                 Application for        Treatment of schizophrenia in adults; treatment of manic
Asenapine patch                 drugs Class
                                                 Clinical trials        or mixed episodes of bipolar I disorder.
                                2.2
Bismuth potassium citrate       Chemical
                                                 Supplemental           Used for chronic gastritis and relieving stomach pain,
capsules (under                 drugs
                                                 application            heartburn and acid regurgitation caused by hyperacidity.
consistency evaluation)
                                                                        Intravenous infusion of this product is indicated for
                                                                        infections caused by methicillin-resistant staphylococcus
                                                                        aureus and other bacteria: septicemia, infective
                                                                        endocarditis, osteomyelitis, arthritis, burns, surgical
Vancomycin                                                              trauma and other superficial secondary infections,
                                Chemical
Hydrochloride             for                    Supplemental           pneumonia, lung abscess, empyema, peritonitis and
                                drugs
injection (under                                 application            meningitis. It may be administered orally for antibiotic-
consistency evaluation)                                                 associated pseudomembranous colitis due to clostridium
                                                                        difficile and staphylococcal enterocolitis, while
                                                                        administration by injection has not been shown to be
                                                                        effective for either indication. Oral vancomycin is not
                                                                        effective for other types of infections.
                                                                        1. Duodenal ulcer. 2.Stomach ulcer. 3.Moderate and
Pantoprazole sodium for         Chemical
                                                 Supplemental           severe reflux esophagitis. 4.Acute upper gastrointestinal
injection     (consistency      drugs
                                                 application            bleeding caused by duodenal ulcer, gastric ulcer, acute
evaluation)
                                                                        gastric mucosal lesion, compound gastric ulcer, etc.


    ②      Drugs (products) granted clinical approval during the Reporting Period
                                        Registration
            Name of drug                                                                Indications
                                          Category
     Salmeterol Xinafoate             Chemical drugs     Asthma: In combination (bronchodilators and inhaled
     and Fluticasone                  Class 4            corticosteroids) for the regular treatment of reversible


                                                                   56
Joincare Pharmaceutical Group                                                             Annual Report 2022


 Propionate Powder for                           obstructive airways disease, including asthma in adults and
 Inhalation                                      children.
                             Chemical drugs
 XYP-001                                         Treatment of idiopathic pulmonary fibrosis (tentative)
                             Class 2.2 and 2.4
                             Therapeutic
                             biological
 Semaglutide Injection                           Type II diabetes
                             products Class
                             3.3
                             Chemical drugs      Advanced solid tumours carrying NTRK1/2/3, ROS1 or ALK
 LZ001
                             Class 1             gene fusions
                                                 1. treat duodenal ulcer and reflux esophagitis.2. treatment of
                                                 duodenal ulcer and reflux esophagitis in children (12-17 years
 Ilaprazole enteric-coated   Chemical drugs      old).3. Treat non-erosive gastroesophageal reflux disease.4.
 pellets                     Class 2.2 and 2.4   treat gastric ulcer.5. eradication of helicobacter pylori. 6.
                                                 prevent gastric ulcer caused by non-steroidal anti-
                                                 inflammatory drugs.
                             Chemical drugs      Luteal function supplementation in infertile women
 Progesterone injection
                             Class 3             undergoing assisted reproductive technology.


③   Drugs (products) granted registration approval during the Reporting Period
                                Registration
      Name of drug                                                         Indications
                                classification
 Levosalbutamol
                                                 Used for treating respiratory diseases such as bronchial asthma
 Hydrochloride Nebuliser     Supplemental
                                                 or asthmatic bronchitis accompanied by bronchospasm in
 Solution                    application
                                                 children.
 (3ml:1.25mg)
 Terbutaline sulfate
                             Chemical drugs      Relieves bronchospasm associated with bronchial asthma,
 solution for nebulized
                             Class 4             chronic bronchitis, emphysema and other lung diseases.
 inhalation
                                                 Used for the treatment of respiratory diseases with excessive
 Acetylcysteine solution     Chemical drugs      secretion of thick mucus, such as acute bronchitis, chronic
 for inhalation              Class 4             bronchitis and its exacerbation, emphysema, mucoviscidosis,
                                                 and bronchiectasis
                                                 It is indicated for bronchiectasis in adults with pulmonary
 Tobramycin Solution for     Chemical drugs
                                                 Pseudomonas aeruginosa infection to control infection and
 Inhalation                  Class 2.4
                                                 improve symptoms.
 Ilaprazole Sodium for
 Injection (Application in   NDA                 Peptic ulcer bleeding
 Indonesia)
                             Preventive
 Recombinant SARS-
                             biological
 CoV-2 Fusion Protein                            Prevention of novel coronavirus infection
                             products
 Vaccine (EUA)
                             Class 1.1
                                                 Clarithromycin is indicated for the treatment of infections
                                                 caused by pathogens sensitive to clarithromycin, including:
                                                 1.Lower respiratory tract infection (bronchitis, pneumonia)
 Clarithromycin Tablets
                             Chemical drugs      2.Upper respiratory tract infection (pharyngitis, sinusitis)
 (consistency evaluation)
                                                 3.Skin and soft tissue infections (folliculitis, cellulitis,
                                                 erysipelas) 4.Local or disseminated infection 5.Mixed infection
                                                 6.Eradication of Helicobacter pylori 7.Dental infection
 Valsartan Capsules
 (consistency                Chemical drugs      Used for treatment of mild to moderate essential hypertension.
 evaluation)
                                                 Long-term treatment of coronary heart disease; prevention of
 Isosorbide Mononitrate
                                                 angina pectoris; treatment of persistent angina pectoris after
 Tablets (consistency        Chemical drugs
                                                 myocardial infarction; treatment of chronic congestive heart
 evaluation)
                                                 failure in combination with digitalis and/or diuretics.

                                                       57
Joincare Pharmaceutical Group                                                            Annual Report 2022


                                              This product is indicated for cefodizine-sensitive
                                              streptococcus, streptococcus pneumoniae, neisseria
                                              gonorrhoeae, branhamella catarrhalis, escherichia coli,
 Cefodizime sodium for                        citrobacter, klebsiella, enterobacter, serratia, roteus, morganella
 injection (consistency    Chemical drugs     morganii, providencia, haemophilus influenzae,
 evaluation)                                  peptostreptococcus, bacteroides, the infections caused by
                                              prevotella including upper urinary tract infection, lower
                                              urinary tract infection, lower respiratory tract infection and
                                              gonorrhea.
                                              It is indicated for the following conditions caused by sensitive
                                              bacteria:
                                              1.Respiratory tract infection;
                                              2.Ear, nose and throat infections;
 Cefuroxime sodium for
                                              3.Urinary tract infection;
 injection (consistency    Chemical drugs
                                              4.Skin and soft tissue infections;
 evaluation)
                                              5.Bone and joint infections;
                                              6.Obstetric and gynaecological infections;
                                              7.Gonorrhea;
                                              8. Other infections;
                                              1.Duodenal ulcer.
                                              2.Stomach ulcer.
 Pantoprazole sodium for
                                              3.Moderate and severe reflux esophagitis.
 injection (consistency    Chemical drugs
                                              4.Acute upper gastrointestinal bleeding caused by duodenal
 evaluation)
                                              ulcer, gastric ulcer, acute gastric mucosal lesion, compound
                                              gastric ulcer, etc.

(4). Cancellation of main R&D projects or the failure to obtain approval for drugs
(products) during the Reporting Period
□Applicable √N/A

(5). R&D accounting policy
√Applicable □N/A

Expenditures on an internal research and development project are classified into expenditures on
the research phase and expenditures on the development phase.

Expenditures on the research phase shall be recognized in profit or loss for the current period when
incurred.

Expenditures on the development phase will be capitalized only when all of the following conditions
are satisfied: it is technically feasible to finish the development of the intangible asset so that it will
be available for use or sale; the Company intends to finish the development of the intangible asset
and use or sell it; it can be demonstrated how the intangible asset will generate economic benefits,
including proving that the intangible assets or the products produced by it will have markets, or the
intangible assets for internal use will be useful; there are adequate technical, financial and other
resources to complete the development and the Company is able to use or sell the intangible assets;
and expenditures on the development phase attributable to the intangible assets can be reliably
measured. The development expenditures that do not satisfy the above conditions shall be
recognized in profit or loss for the current period.




                                                    58
Joincare Pharmaceutical Group                                                            Annual Report 2022


Our research and development projects enter the development stage after meeting the above
conditions and forming the project through the technical and economic feasibility studies.

Capitalized expenditures on the development phase are shown as development expenditures on the
balance sheet and reclassified as intangible assets on the date the project meets the intended purpose.

Capitalization conditions for specific research and development projects are as follows:

①     For research and development projects that are not required to obtain clinical approvals, the
period from the beginning of research and development to before the pilot phase is treated as the
research phase, and all expenditures shall be recognized in profit or loss for the current period when
incurred; the period from the pilot phase to the obtaining of production approvals is treated as the
development phase, and all expenditures shall be recognized as development expenditures and
reclassified as intangible assets after the obtaining of production approvals.

②     For research and development projects that require clinical approval, the period from the
beginning of research and development to the obtaining of clinical approval is treated as the research
phase, and all expenditures incurred shall be recognized in profit or loss for the current period when
incurred; the period from the obtaining of clinical approval to the obtaining of production approval
is treated as the development phase, and the expenditures shall be recognized as development
expenditures and reclassified as intangible assets after the obtaining of production approval.

③External technology transfer fees and the cost of purchasing clinical approvals can be recognized
directly as development expenditures, and subsequent expenditures are accounted for in accordance
with ① and ② above.

④The Company reviews the latest research and development status of each project at the end of
each year and if the research and development project no longer qualifies for the development stage,
the corresponding development expenditure are recognized in profit or loss for the current period.

⑤Where it is impossible to differentiate the expenditures on the research phase and the expenditures
on the development phase, all the research and development expenditures are recognized in profit
or loss for the current period.



(6). R&D expenditures
Horizontal comparison
√Applicable □N/A

                                                                    Unit: 10,000 Yuan Currency: RMB
                                                           Proportion of                          Ratio of
                                                                             Proportion of
                                                               R&D                            capitalized R&D
     Comparable peer                                                             R&D
                          R&D expenditures amount         expenditures to                       expenditures
       companies                                                            expenditures to
                                                           revenues (%)                              (%)
                                                                             net assets (%)

 Fosun Pharma                           497,500.00                 12.75             10.28              22.93



                                                     59
Joincare Pharmaceutical Group                                                         Annual Report 2022


 Kelun Pharma                               179,953.47            10.42            12.99                3.50
 CR Double-Crane                             63,974.38              7.02            6.11               35.98
 Humanwell Healthcare
                                            106,053.87              5.16            8.19               23.58
 (Group)
 North China
                                             50,467.67              4.86            8.29               74.85
 Pharmaceutical
 Average R&D expenditures in the same industry                                                    179,589.88
 Proportion of R&D expenditures to revenues during
                                                                                                      10.26
 the Reporting Period (%)
 Proportion of R&D expenditures to net assets during
                                                                                                        7.99
 the Reporting Period (%)
 Ratio of capitalized R&D expenditures during the
                                                                                                        9.96
 Reporting Period (%)
Notes: 1. The data regarding comparable companies listed above are from each company's 2021
annual report;
2. The average R&D expenditures in the same industry is the arithmetic average of the R&D
expenditures of five comparable companies listed above.

Statement on material changes in R&D expenditures and rationality of R&D expenditures
proportion and capitalization proportion
√Applicable □N/A
Mainly due to the fact that the “Recombinant SARS-CoV-2 Fusion Protein Vaccine (重组新型冠
状病毒融合蛋白疫苗)” of Livzon MAB was included in the emergency use in sequential booster
immunization against a novel coronavirus SARSCoV-2 in September 2022, and the accumulated
development expenditure of this project was transferred to intangible assets.

Investment in major R&D projects
√Applicable □N/A
                                                                     Unit: 10,000 Yuan Currency: RMB
                                                                                 Proportion of
                                R&D            Expensed          Capitalized
                                                                                     R&D           YoY
       R&D project           expenditures        R&D               R&D
                                                                                expenditures to change (%)
                               amount         expenditures      expenditures
                                                                                 revenues (%)
 Indacaterol Maleate
                                 1,318.71                0.02       1,318.69               0.08      206.37
 Powder for Inhalation
 Fluticasone Propionate
                                   646.40              646.40              -               0.04       -32.98
 Nebulizable Suspension
 Formoterol Fumarate
                                 1,116.59              219.48         897.11               0.07       -28.97
 Solution for Inhalation
 Salmeterol Xinafoate and
 Fluticasone Propionate          3,042.37              577.16       2,465.20               0.18      131.93
 Powder for Inhalation
 XYP-001                         2,589.01              479.56       2,109.45               0.15     5,527.28
 Mometasone Furoate and
 Formoterol Fumarate
                                   145.08              145.08              -               0.01       -65.44
 Dihydrate Inhalation
 Aerosol
 Formoterol Fumarate
                                   432.91              432.91              -               0.03         9.13
 Inhalation Aerosol
 V-01(COVID-19)               39,010.09         32,244.11         6,765.98               2.27       -20.57
 LZM009(PD-1)                  6,661.86          4,796.98         1,864.88               0.39        31.18
 Triptorelin acetate             6,359.08          6,219.99           139.10               0.37        44.42

                                                         60
Joincare Pharmaceutical Group                                                             Annual Report 2022


 sustained-release
 microspheres for injection
 (1 month release)
 LZM012(IL-17A/F)              3,932.42         3,932.42                   -               0.23        154.78
 Blonanserin                       181.04           181.04                   -               0.01        -84.84
Notes:
1. The projects listed above are the main R&D projects conducted by the Company, of which
project Blonanserin Tablets is a Priority Review & Approval project.
2. The main reason for the quite significant YoY change in our R&D expenditure is that our R&D
projects were in different R&D stages during the Reporting Period.

3. Sales of drugs (products) of the Company
(1). Analysis of main sales model
√Applicable □N/A

Please refer to the “Overview on the businesses of the Company during the Reporting Period” in
this Chapter.

(2). Analysis of selling expenses
Components of selling expenses
√Applicable □N/A
                                                                             Unit: 10,000 Yuan Currency: RMB
                                     Amount incurred in the             Proportion of amount incurred in the
                Item
                                        current period            current period to total selling expenses (%)
  Business promotion expenses                      437,208.76                                             88.31
  Employee compensation                             45,687.52                                              9.23
  Entertainment and travel
                                                      5,036.34                                                  1.02
  expenses
  Business meeting expenses                          1,369.68                                               0.28
  Others                                             5,777.95                                               1.17
               Total                               495,080.25                                             100.00

Horizontal comparison
√Applicable □N/A
                                                                             Unit: 10,000 Yuan Currency: RMB
                                                                            Proportion of selling expenses to
    Comparable peer companies                Selling expenses
                                                                                     revenues (%)
  Fosun Pharma                                             909,900.00                                    23.33
  Kelun Pharma                                             502,233.28                                    29.07
  CR Double-Crane                                          280,731.43                                    30.81
  Humanwell Healthcare (Group)                             400,667.12                                    19.50
  North China Pharmaceutica                                216,131.38                                    20.81
  Total selling expenses of the Company during the Reporting Period                                 495,080.25
  Proportion of selling expenses to revenues during the Reporting
                                                                                                         28.88
  Period (%)
Note: The data regarding comparable companies listed above are from each company's 2021
annual report.

Statement on material changes in selling expenses and rationality of selling expenses
√Applicable □N/A
During the Reporting Period, the Company's selling expenses were RMB4,950.8025 million,
accounting for 28.88% of revenues, representing a year-on-year decrease of 1.26%. The increase
was mainly due to more efforts to promote products and brands, and an increase in selling expenses

                                                      61
Joincare Pharmaceutical Group                                                 Annual Report 2022


in prescription drugs which recorded significant sales growth during this period. Looking forward,
the Company will continue to deepen the reform of the marketing system to optimize sales channels
and increase the cost efficiency for high profitability.


4. Others
√Applicable □N/A
(V) Analysis of investments
Overall analysis of equity investments
√Applicable □N/A
During the Reporting Period, the Company carried out strategic investments in accordance with
our development plans as follow:




                                                  62
             Joincare Pharmaceutical Group                                                                                                                                                           Annual Report 2022


             1. Major equity investment
             √Applicable □N/A
                                                                                                                                                                                        Unit: 10,000 Yuan Currency: RMB
                                         Whether                                                                                                                                                              Litig
                                                                                                      In the       Item on the                                                                      Impact
                                       the target is                                                                                                        Invest                       Expect               ation   Disclos    Disclos
                                                                                                  Consolidation      financial      Source                             Status as of                 of gain
  Name of                                primarily     Investment    Investment   Percentage of                                              Partner (if     ment                           ed                invol    ure          ure
                 Principal business                                                                scope of the     statement          of                             balance sheet                 or loss
  investee                              engaged in       method        amount     shareholding                                               applicable)   period                        return                ved    date (if    index
                                                                                                  Company or            (if          funds                                date                      for the
                                        investment                                                                                                         (if any)                      (if any)               or     any)      (if any)
                                                                                                       not         applicable)                                                                      period
                                          business                                                                                                                                                             not

                 Primarily engaged
                 in technology
                 development,
                 technology
Shanghai Sheo
                 consulting,
Pharma
                 technology transfer                                                                                   Long-term                                         Capital
Technology                                               Capital                                                                    Own                     Long
                 and technology            No                         1,700.00       21.70%            No                equity                 N/A                    contribution         -       230.92     No      N/A        N/A
Co., Ltd.(上海                                          injection                                                                   funds                   term
                 services in the                                                                                       investment                                     was completed
偕怡医药科技
                 fields of medical
有限公司)
                 technology,
                 biotechnology and
                 computer
                 technology.




                 Primarily engaged
                                                                                                                                                                        The parties
                 in pharmaceutical
                                                                                                                                                                            have
                 manufacturing;
Jiaozuo                                                                                                                                                                completed a
                 health care food
Jianfeng                                                                                                                                                                total capital
                 manufacturing;                            New
Biotech Co.,                                                                                                                        Own                     Long      contribution of
                 food                      No          establishme    3,325.00       66.50%           Yes                 N/A                Greenanew                                      -          -       No      N/A        N/A
Ltd.(焦作健风                                                                                                                       funds                   term          RMB10
                 manufacturing;                             nt
生物科技有限                                                                                                                                                             million in
                 food additive
公司)                                                                                                                                                                  proportion to
                 manufacturing;
                                                                                                                                                                            their
                 cosmetics
                                                                                                                                                                      shareholdings
                 manufacturing, etc.




                                                                                                                  63
            Joincare Pharmaceutical Group                                                                                                          Annual Report 2022


                 Primarily engaged
                 in the research and
                 development of
Jiangsu Atom     human medicine,
Bioscience &     veterinary
Pharmaceutica    medicine,                                                                 Long-term                            Capital
                                                Capital                                                 Own           Long
l Technology     pesticides, health      No                 3,000.00   3.35%    No           equity             N/A           contribution     -   -510.52   No     N/A   N/A
                                               injection                                                funds         term
Co., Ltd.(江苏   care products and                                                         investment                        was completed
新元素医药科     chemical products,
技有限公司)      product technology
                 transfer, technology
                 consulting, project
                 cooperation.
                 Engaged in all the
                 business of
                 manufacturers,
                 producers,
                 importers,
                 exporters,
                 purchasers,
                 vendors,
                 distribution agents
                 and distributors of
LIVZON                                                                                                                          Capital
                 patents,                         New
BIOLOGICS                                                                                               Own           Long    contribution
                 pharmaceuticals,        No   establishme   0.0152     60.43%   Yes           N/A               N/A                            -      -      No     N/A   N/A
(MALAYSIA)                                                                                              funds         term    was not yet
                 medicines,                        nt
SDN. BHD                                                                                                                       completed
                 nutritional supplem
                 ents, health care
                 products, drugs and
                 vaccine products,
                 and all goods,
                 compounds, and
                 substances
                 commonly used in
                 connection
                 therewith.
Shenzhen         Biochemical                                                                                                    Capital
Kangti           product technology                                                        Long-term                         contribution of
                                                Capital                                                 Own           Long
Biomedical       research          and   No                 1,000.00   1.42%    No           equity             N/A          RMB6 million             -      No     N/A   N/A
                                               injection                                                funds         term
Technology       development;                                                              investment                        was completed
Co., Ltd.(深圳   technology




                                                                                      64
           Joincare Pharmaceutical Group                                                                                                                                                                      Annual Report 2022


康体生物医药     services,
科技有限公       technology
司)              development,
                 technical
                 consulting,
                 technology
                 exchange,
                 technology transfer,
                 technology
                 promotion

   Total                  /                /              /          9,025.0152          /                   /                 /            /              /           /              /                      -279.60     /            /   /
           Note: Jiangsu Atom Bioscience & Pharmaceutical Technology Co., Ltd. completed its Series C financing on 18 March 2022.


           2. Major non-equity investment
           □Applicable √N/A

           3. Financial assets measured at fair value
           √Applicable □N/A
                                                                                                                                                                                                    Unit: Yuan Currency: RMB
                                         Amount at the        Gain or loss on           Accumulated                Impairment              Amount of            Amount of disposal
                                                                                                                                                                                                             Amount at the end of
                 Type of assets         beginning of the      change in fair value   change in fair value        provision for the       purchase during       / redemption during        Other change
                                                                                                                                                                                                                 the period
                                             period           for the period          included in equity              period               the period               the period
               Shares                        215,317,489.90                      -           6,682,661.01                            -                   -           212,384,666.97                      -             9,615,483.94
               Private Equity                701,277,471.64                      -          33,186,359.03                            -          884,764.97            48,229,068.96                      -           687,119,526.68
               Derivatives                     7,376,328.32          -1,943,816.75                       -                           -                   -                        -                      -             5,432,511.57
               Others                        492,287,415.88                      -          40,418,396.69                            -                   -            35,481,944.14                      -           497,223,868.43
               Others                        177,262,015.99         -73,706,840.89                       -                           -           27,978.31                        -                      -           103,583,153.41
                       Total               1,593,520,721.73         -75,650,657.64          80,287,416.73                            -          912,743.28           296,095,680.07                      -         1,302,974,544.03


           Information on investment in securities
                                                                                                                                                                                                    Unit: Yuan Currency: RMB




                                                                                                                       65
Joincare Pharmaceutical Group                                                                                                                                                               Annual Report 2022


                                                                                                                                       Amount
                                                                              Carrying         Gain or loss on    Accumulated                                            Profit         Carrying
                                               Initial                                                                                    of            Amount of
  Type of      Securities    Securities                      Source of     amount at the       change in fair    change in fair                                         or loss       amount at the       Accounting
                                             investment                                                                                purchase       disposal during
 securities      code       abbreviation                       fund         beginning of        value for the    value included                                         for the        end of the            item
                                                cost                                                                                  during the         the period
                                                                             the period            period           in equity                                           period           period
                                                                                                                                        period
                                                                                                                                                                                                          Other equity
                                                               Own
 Shares       601881        China Galaxy    144,915,000.00                  212,384,666.97                   -                    -            0.00    212,384,666.97         -                       -    instrument
                                                               funds
                                                                                                                                                                                                          investment
                                                                                                                                                                                                            Financial
                            Kunlun                             Own
 Shares       00135                           4,243,647.64                    5,976,656.00       -1,001,142.10                    -            0.00              0.00         -         4,975,513.90      assets held
                            Energy                             funds
                                                                                                                                                                                                           for trading
                                                                                                                                                                                                            Financial
                            Penghua                            Own
 Funds        206001                           150,000.00                      940,162.94            -5,873.00                    -            0.00              0.00         -           934,289.94      assets held
                            Fund                               funds
                                                                                                                                                                                                           for trading
                                                                                                                                                                                                            Financial
                            Huadong                            Own
 Shares       000963                             39,851.86                   13,250,402.40       2,175,439.20                     -            0.00              0.00         -        15,425,841.60      assets held
                            Medicine                           funds
                                                                                                                                                                                                           for trading
                            Beam                                                                                                                                                                            Financial
                                                               Own
 Shares       BEAM(US)      Therapeutics,    34,209,846.54                  157,094,794.65     -74,876,557.68                     -            0.00              0.00         -        82,218,236.97      assets held
                                                               funds
                            Inc.                                                                                                                                                                           for trading
                                                                                                                                                                                                            Financial
                                                               Own
 Others                                          27,978.31                                 -         1,292.69                     -       27,978.31              0.00         -            29,271.00      assets held
                                                               funds
                                                                                                                                                                                                           for trading
 Total                /           /         134,376,477.81       /          389,646,682.96     -73,706,840.89                     -       27,978.31    212,384,666.97         -       103,583,153.41             /


Information on investment in private equity fund
√Applicable □N/A

                                                                          Gain or
                                                                                                                                                                 Amount of
                                                                           loss on                                   Impairment               Amount of
                                                 Amount at the                            Accumulated change                                                      disposal /                      Amount at the
                                                                         change in                                    provision                purchase                                Other
                Type of assets                  beginning of the                          in fair value included                                                 redemption                        end of the
                                                                         fair value                                    for the                during the                              change
                                                     period                                      in equity                                                        during the                         period
                                                                           for the                                     period                   period
                                                                                                                                                                    period
                                                                           period
 Qianhai Equity Investment Fund(前海股权
                                                  264,930,500.00                      -           -21,551,757.83                      -                    -                      -          -    243,378,742.17
 投资基金)




                                                                                                     66
Joincare Pharmaceutical Group                                                                                                                                                                  Annual Report 2022


 PANTHEON D,L.P.                                            3,715,566.69                  -              2,238,734.51                  -                        -                      -        -        5,954,301.20
 Shanghai Yunfeng Xinchuang Equity
 Investment Center(上海云锋新创股权投资                    94,040,236.88                  -              8,210,913.25                  -                        -     34,315,445.77             -      67,935,704.36
 中心)
 Shanghai Jingyi Investment Center(上海经
                                                           66,175,062.50                  -              7,441,297.41                  -                        -                      -        -      73,616,359.91
 颐投资中心)


Information on investment in derivatives
√Applicable □N/A
                                                                                                                                                                                                     Unit: 10,000 Yuan
                         Is this a                         Initial                                                                                                        Investment      Percentage of
Name of the                                                                                        Investment                       Amount of
                          related         Type of        investment                                                Amount of                                               amount at investment amount Actual gain or
operator of   Related                                                   Commence    Maturity         amount                          disposal            Impairment
                           party        derivatives       amount of                                              purchase during                                              the      to the net assets of loss for the
derivatives relationship                                                ment date    date       at the beginning                    during the         provision (if any)
                         transact       investment       derivatives                                               the period                                              end of the the Company at the      period
investment                                                                                        of the period                       period
                            ion                          investment                                                                                                          period     end of the period
                                      Forward foreign
Financial     Non-related
                            No       exchange contract       2,108.32    2021/8/3   2022/2/8            2,269.07                -           2,071.02                  -            -                0.00%          58.89
institution   party
                                           (sell)
                                      Forward foreign
Financial     Non-related
                            No       exchange contract       7,708.90    2021/9/2   2022/3/31           7,835.52                -           7,572.32                  -            -                0.00%         399.98
institution   party
                                           (sell)
                                      Forward foreign
Financial     Non-related
                            No       exchange contract      11,312.51 2021/10/11    2022/4/7          11,589.76                 -          11,227.57                  -            -                0.00%         183.27
institution   party
                                           (sell)
                                      Forward foreign
Financial     Non-related
                            No       exchange contract      18,301.91 2021/11/1     2022/5/9          18,602.45                 -          18,387.38                  -            -                0.00%          40.70
institution   party
                                           (sell)
                                      Forward foreign
Financial     Non-related
                            No       exchange contract      17,268.19 2021/12/10    2022/6/13         17,664.55                 -           9,153.79                  -            -                0.00%         -21.70
institution   party
                                           (sell)
                                      Forward foreign
Financial     Non-related
                            No       exchange contract      17,960.93    2022/1/5   2022/7/26                  -        17,960.93          18,439.57                  -            -                0.00%        -384.03
institution   party
                                           (sell)
                                      Forward foreign
Financial     Non-related
                            No       exchange contract       8,197.90 2022/2/10     2022/8/8                   -         8,197.90           8,582.48                  -            -                0.00%        -345.20
institution   party
                                           (sell)




                                                                                                          67
Joincare Pharmaceutical Group                                                                                                             Annual Report 2022


                                  Forward foreign
Financial     Non-related
                            No   exchange contract   18,437.37 2022/3/11     2022/9/1         -   24,878.83   26,386.53   -           -      0.00%     -1,310.43
institution   party
                                       (sell)
                                  Forward foreign
Financial     Non-related
                            No   exchange contract   12,507.52   2022/4/7   2022/10/10        -   16,323.43   16,845.74   -           -      0.00%      -769.47
institution   party
                                       (sell)
                                  Forward foreign
Financial     Non-related
                            No   exchange contract    7,037.84   2022/5/5   2022/11/30        -    7,037.84    7,349.49   -           -      0.00%      -292.77
institution   party
                                       (sell)
                                  Forward foreign
Financial     Non-related
                            No   exchange contract   10,888.09   2022/6/2   2022/12/23        -   14,447.06   15,034.70   -           -      0.00%      -559.15
institution   party
                                       (sell)
                                  Forward foreign
Financial     Non-related
                            No   exchange contract    9,319.83   2022/7/4   2023/1/30         -   14,702.35   14,645.26   -     607.17       0.03%      -519.13
institution   party
                                       (sell)
                                  Forward foreign
Financial     Non-related
                            No   exchange contract   10,632.66   2022/8/2    2023/2/3         -   16,163.56   14,514.10   -    2,183.36      0.10%      -480.15
institution   party
                                       (sell)
                                  Forward foreign
Financial     Non-related
                            No   exchange contract   10,560.82   2022/9/5   2023/2/24         -   12,986.49    7,733.99   -    5,376.80      0.24%      -142.27
institution   party
                                       (sell)
                                  Forward foreign
Financial     Non-related
                            No   exchange contract   17,297.95 2022/10/8     2023/4/4         -   19,447.09    8,612.85   -   10,392.16      0.47%       214.17
institution   party
                                       (sell)
                                  Forward foreign
Financial     Non-related
                            No   exchange contract   12,377.21 2022/11/1    2023/4/24         -   15,220.85    3,494.34   -   11,361.13      0.52%         0.41
institution   party
                                       (sell)
                                  Forward foreign
Financial     Non-related
                            No   exchange contract    9,034.15 2022/12/2    2023/6/26         -    9,034.15      80.36    -    8,939.17      0.41%         0.80
institution   party
                                       (sell)
                                 Forward foreign
Financial     Non-related
                            No   exchange contract   14,528.73 2022/4/21     2022/8/4         -   14,528.73   14,986.04   -           -      0.00%       333.01
institution   party
                                 (buy)
                                 Forward foreign
Financial     Non-related
                            No   exchange contract     925.07 2022/5/10     2022/12/15        -     925.07      893.48    -           -      0.00%        -38.11
institution   party
                                 (buy)
Financial     Non-related        Forward foreign
                            No                        1,358.88 2022/9/22    2023/3/21         -    1,358.88           -   -    1,355.92      0.06%             -
institution   party              exchange contract




                                                                                         68
Joincare Pharmaceutical Group                                                                                                                                                                                 Annual Report 2022


                                       (buy)
                                       Forward foreign
   Financial Non-related
                                  No   exchange contract            831.80 2022/11/14      2023/2/15                     -            831.80             386.81                   -        461.69                  0.02%              1.12
  institution party
                                       (buy)
                                       Forward foreign
   Financial Non-related
                                  No   exchange contract          2,402.70 2022/12/2       2023/6/26                     -          2,402.70           1,174.90                   -      1,257.76                  0.06%              1.89
  institution party
                                       (buy)
                                       Forward foreign
   Financial Non-related
                                  No   exchange contract                    - 2022/12/22   2023/1/30                     -          2,091.39                   -                  -      2,089.38                  0.09%                  -
  institution party
                                       (buy)
                                       Forward foreign
   Financial Non-related
                                  No   exchange contract                    - 2022/12/29   2023/2/3                      -          2,093.79                   -                  -      2,089.38                  0.09%                  -
  institution party
                                       (buy)
                          Total                                220,999.29         --           --              57,961.35         200,632.85          207,572.71                   -     46,113.94                  2.09%         -3,786.71
Source of funds for derivatives investment                 Own funds
Litigation involved (if applicable)                        Not applicable
Disclosure date of the announcement in relation to the
approval of investment in derivatives by the Board (if 31 March 2022
any)
Disclosure date of the announcement in relation to the
approval of derivatives investment by the general      Not applicable
meeting of shareholders (if any)

                                                           To effectively manage the uncertainty of exchange rate fluctuations on assets denominated in foreign currency of the Company, foreign exchange forward contracts and other
                                                           financial derivatives are employed to lock relevant exchange rates for the purpose of hedging. The Company has formulated the Management System for Financial Derivatives
                                                           Trading (《金融衍生品交易业务管理制度》) in relation to the operation and control of foreign exchange derivatives: 1. Market risk: the uncertainty of exchange rate
                                                           fluctuations in the foreign exchange market has led to higher market risk in foreign exchange forward business. Control measures: The Company’s foreign exchange forward
                                                           business is entered into for hedging exchange rate risk associated with assets denominated in US dollar and lock the future exchange settlement price of such assets. It is
                                                           designed to be used as a hedging instrument. Such foreign exchange derivatives shall not be used for speculative trading. The principle of prudence and conservation shall be
Risk analysis of derivatives position held during the
                                                           observed so as to effectively prevent market risk. 2. Operational risk: operational risk arises from imperfect internal process, improper operation, system failure and other
Reporting Period and explanation of control measures
                                                           factors. Control measures: The Company has formulated the corresponding management measures, clearly defined the responsibilities of all parties, improved the review and
(including but not limited to market risk, liquidity risk,
                                                           approval process and established supervisory mechanism, so as to effectively reduce operational risk. 3. Legal risk: The Company’s foreign exchange forward business is
credit risk, operational risk, legal risk, etc.)
                                                           subject to applicable laws and regulations, and shall clearly stipulate the relationship of rights and obligations with financial institutions. Control measures: In addition to
                                                           strengthening the knowledge of laws and regulations and market rules in the Company’s responsible department, the Company’s legal department shall also strictly review
                                                           various business contracts, agreements and other documents, specify the rights and obligations, and strengthen compliance inspection, so as to ensure that the Company’s
                                                           investment and operation in derivatives have met the requirements of applicable laws and regulations as well as the Company’s internal systems.

                                                           In order to manage the uncertainty risk caused by price fluctuations of bulk commodities on the purchase cost of raw materials of the Company, financial derivatives such as
                                                           commodity futures contracts are employed to hedge raw materials. The Company has formulated the Internal Control System for Commodity Futures Hedging Business (《商




                                                                                                                   69
Joincare Pharmaceutical Group                                                                                                                                                                               Annual Report 2022


                                                       品期货套期保值业务内部控制制度》) to standardize the management and risk control of commodity futures derivatives: 1. Market risk: the uncertainty of price changes of
                                                       bulk commodities has led to greater market risk in futures business. Control measures: The Company’s futures hedging business shall not carry out speculative trading, the
                                                       operation principle of prudence and conservation shall be observed, the number of hedging transactions shall be strictly limited, such that it does not exceed the actual number
                                                       of spot transactions, and the futures position shall not exceed the spot volume for hedging purpose. 2. Operational risk: operational risk arises from imperfect internal process,
                                                       improper operation, system failure and other factors. Control measures: The Company has formulated the corresponding management system, clearly defined the division of
                                                       responsibilities and approval process, and established an improved supervisory mechanism, so as to effectively reduce operational risk through risk control of business process,
                                                       decision-making process and transaction process. 3. Legal risk: The Company’s commodity futures hedging business is subject to applicable laws and regulations, and shall
                                                       clearly stipulate the relationship of rights and obligations with financial institutions. Control measures: In addition to strengthening the knowledge of laws and regulations and
                                                       market rules in the Company’s responsible department, the Company’s legal department shall also strictly review various business contracts, agreements and other documents,
                                                       specify the rights and obligations, and strengthen compliance inspection, so as to ensure that the Company’s investment and operation in derivatives have met the requirements
                                                       of applicable laws and regulations as well as the Company’s internal systems.
Change in market price or fair value of the derivatives
invested during the Reporting Period, the specific
                                                        Gains and losses arising from change in fair value of the forward foreign exchange contracts, option contracts and commodity futures contracts during the Reporting Period
method, related assumptions and parameters used in the
                                                        were RMB-2.5561 million.
analysis of the fair value of derivatives shall be
disclosed
Explanation as to whether there has been a material
change in the accounting policy and accounting
principles for the Company’s derivatives during the   No
Reporting Period as compared with the previous
reporting period




                                                       Due to the growing import and export business of the Company, a large amount of foreign exchange transactions are required. To avoid and prevent foreign exchange risk,
                                                       we are of the view that the forward foreign exchange derivatives trading business carried out by the Company and its subsidiaries are in line with the actual development
Specific opinion of independent Directors on
                                                       needs of the Company. When the Board reviewed this proposal, the relevant
investment in derivatives and risk control of the
                                                       decision-making procedures were in compliance with the Company Law, the Securities Law, the Rules Governing the Listing of Stocks on the Shanghai Stock Exchange and
Company
                                                       other relevant laws and regulations and the provisions in the Articles of Association of the Company. In view of above, we concurred that the Company conducted foreign
                                                       exchange derivatives trading business with its own funds within the limit approved by the Board.




                                                                                                                 70
       Joincare Pharmaceutical Group                                                                           Annual Report 2022


       4. Progress of Material Asset Restructurings of the Company during the Reporting Period
       □Applicable √N/A

       (VI) Sale of major assets and equity
       □Applicable √N/A

       (VII) Analysis of major controlled and invested companies
       √Applicable □N/A

                                                                                                                   Unit: 10,000 Yuan

                  Nature of      Main products and         Registered                                                 Operating
  Company                                                               Asset size    Net assets    Revenues                       Net profit
                  business           services               capital                                                    profit

                              R&D, production and
                              sale of oral liquids,
                              tablets (hormone-
                              containing), aerosols
                              (including hormone-
Taitai                        containing aerosols),
                 Industry                                      10,000    48,195.86      35,935.68      26,623.31        9,040.71    8,470.05
Pharmaceutical                inhalation formulations
                              (solution for inhalation)
                              (hormone-containing),
                              nasal sprays (hormone-
                              containing), and dietary
                              supplements
                              Wholesale and retail of
                              skincare products,
                              cosmetics, and other
Taitai
                 Industry     daily necessities;                  500        462.49         59.47        293.69           -56.39        -64.87
Biotechnology
                              domestic trading
                              business, and R&D of
                              dietary supplements
                              Powders for injection
                              (including penicillin-
                              containing powders),
                              tablets, hard capsules,
                              APIs, sterile APIs,
                              inhalation formulations
Haibin Pharma    Industry     (solution for inhalation),       70,000   270,567.22     157,802.84     176,563.89       39,159.15   33,810.82
                              powders for inhalation,
                              pharmaceutical
                              excipients, R&D
                              technical services, and
                              testing technical
                              services
                              Manufacturing and sale
                              of pharmaceutical
                              intermediates and APIs
Xinxiang                      (excluding proprietary
                 Industry                                      17,000   157,414.92      38,007.93      76,236.57        7,717.10    6,803.30
Haibin                        Chinese medicine or
                              TCM decoction pieces)
                              (excluding hazardous
                              chemicals)
                              Production and sale of
                              self-produced dietary
Health
                 Industry     supplements, TCM             HKD7,317      13,541.87       9,352.64       3,113.88         -552.83       -498.57
Pharmaceutical
                              decoction pieces, and
                              drug products
                              R&D of new
                              pharmaceutical
                              products, dietary
                              supplements, medical
                              devices, diagnostic
Shanghai                      reagents, and
                 Industry                                       5,000    16,314.32      11,460.04       9,813.17        2,808.70    2,666.34
Frontier                      pharmaceutical
                              intermediates, and
                              provision of relevant
                              technical consulting,
                              technical services and
                              technology transfer




                                                                        71
           Joincare Pharmaceutical Group                                                                        Annual Report 2022


                                Technology
                                development of
                                biologics; investment in
                                industry, domestic
                                trading and economic
                                information consulting.
Hiyeah Industry    Commerce     Production of beverages        17,800          617.63         566.30            6.25       -41.55       -41.55
                                and solid beverages;
                                whole sale of pre-
                                packaged food
                                (excluding reheatable
                                food)

                                Wholesale and retail of
                                skincare products,
                                cosmetics, and other
Joincare Daily-
                   Commerce     daily necessities;              2,500         3,858.95      3,852.62               -        -0.08        -1.46
Use
                                domestic trading
                                business, and R&D of
                                dietary supplements
                                Screening of human
                                disease-specific genes,
                                R&D, production, sale
                                and technical consulting
                                service for genetic
                                engineering drugs and
Taitai
                   Industry     diagnostic reagents,            5,000         3,635.48      3,635.48            0.17         5.81         5.81
Genomics
                                wholesale of medical
                                devices, and in vitro
                                diagnostic reagents
                                (except for diagnostic
                                reagents under special
                                management)
                                Forensic evidence
                                identification; forensic
Appraisal                       toxicology identification
                   Commerce     (limited to ethanol                 -          964.40         888.16         153.10        -54.39       -57.01
institution
                                detection and drug
                                detection)。
                                Investment in power
                                and industry; domestic
Fenglei Electric
                   Investment   commerce, and material         10,000     29,278.31        14,282.70               -       91.86        91.86
Power
                                supply and marketing
                                industry
Hong Kong
                   Investment   Investment and trading          HKD1      35,457.68           835.04               -      131.87       120.99
Pharmaceutical
                                R&D, production and
                                sale of pharmaceuticals,
                                chemical APIs,
Jiaozuo
                   Industry     biological APIs,               50,000    185,715.54        88,087.38     159,030.74     29,330.87    25,470.94
Joincare
                                pharmaceutical
                                intermediates, and
                                biological products
Topsino            Commerce     Investment and trading      HKD89,693    185,901.35       128,993.00               -    44,136.90    44,080.67
                                According to the laws
Health
                   Investment   where it was                    USD5          2,834.63      2,834.63               -            -            -
Investment
                                incorporated
                                R&D, production,
                                storage, transportation
                                and sale of chemical
                                APIs (including
                                intermediates) and
Joincare Haibin    Industry     pharmaceuticals. Import        50,000     98,129.06        82,133.68      68,579.14     42,109.14    36,773.72
                                and export business and
                                domestic trading
                                (excluding State
                                controlled or franchised
                                goods)
                                R&D, production and
                                sale of formula food,
Joincare Special
                   Industry     dietary products and            2,000         1,720.47           4.46              -      -311.98      -228.08
Medicine Food
                                food for special medical
                                use
                                Drug R&D, production,
Livzon Group       Industry                                    93,555   2,486,482.54     1,493,625.16   1,262,957.90   235,055.56   195,554.02
                                manufacturing and sale


           (VIII) Structured entities controlled by the Company

                                                                         72
Joincare Pharmaceutical Group                                                                Annual Report 2022


□ Applicable √N/A

VI. Discussion and analysis of the Company's future development
(I) Industry landscape and trend
For details, please refer to the “Basic information on industry” in this chapter.

(II) Company's strategies for business development
√Applicable □N/A

Taking scientific and technological innovation as a strategic priority and executing our dual-drive strategy
of developing platforms of both innovative medicines and high-barrier complex formulation, we have
been evolving into a world-wide influential innovative pharmaceutical enterprise paying great attention to
people's livelihood and actively undertaking social responsibilities. Over the years, the Company has been
committed to developing itself in the pharmaceutical field, and has grown into an integrated
pharmaceutical enterprise covering multiple areas including chemical pharmaceuticals, biologics,
chemical APIs and intermediates, traditional Chinese medicine, diagnostic reagents and equipment. In the
future, the Company will continue to increase R&D expenditures to improve its research and innovation
capacity, accelerate the optimization and adjustment of its product structure, fully leverage its existing
market advantages, and actively deepen the reform of the marketing system, to promote its sustainable
and steady business growth.

(III) Business plan
√Applicable □N/A
The year of 2023 is crucial for the transformation of the Chinese market to the “post-pandemic” era, as
well as an important window period for the reshaping of the pharmaceutical industry and the
transformation and upgrading of enterprises. The main business plans for each business segment of the
Company in 2023 are set as follows:
1.R&D Center
R&D and innovation are the hard power of the Company to maintain sustainable development. The Company
will, on one hand, define the direction of research and development strategy, and screen and evaluate key high-
barrier varieties, to enrich and diversify the pipelines; and will, on the other hand, promote product
transformation, and effectively advance the research and clinical development of existing core products, to
accelerate the launching process.
(1) Strategic plannings of R&D and innovation: In recent years, focusing on inhalation formulations, the Group
has conducted in-depth research on a few of carefully selected new products with high clinical value and
promising market potential, and has achieved good performance. In the future, under the existing R&D pipeline,
the Group will focus on the following R&D areas: 1) Inhalation formulations: continue to enrich the pipeline
and portfolio of inhalation formulations; 2) Complex injections: Complex injections are mainly microcrystals
and liposome injections, with broad clinical application prospect and high technical barrier, and will be added
to the Company’s R&D platforms of high-barrier complex formulation ; 3) New drug delivery devices: drugs
for respiratory treatment are usually delivered through combined medical instruments with a complex structure,
thus posing high requirements on the structural design, performance and quality control. The Group will
develop supporting drug delivery devices based on the progress of R&D of drugs for respiratory diseases,
improve the industrial chain of inhalation formulations, and enhance the added value and core competitive
strengths of products to be launched.
(2) Accelerating the commercialization of existing drugs candidates under R&D: Currently, the Company has
244 drug candidates under R&D, including 45 high-barrier complex formulations. In 2023, the Company will
focus on promoting the marketing application of indacaterol maleate powder for inhalation, salmeterol
xinafoate - fluticasone propionate powder for inhalation, triptorelin acetate microspheres for injection (1-month

                                                       73
Joincare Pharmaceutical Group                                                                Annual Report 2022


sustained release) and clinical research of XYP-001, Recombinant Anti-Human IL-17A/F Humanized
Monoclonal Antibody Injection and other key varieties, while actively promoting the establishment and
research of innovative high-barrier complex formulations.
(3) In addition to independent research and development, the Company will continue to focus on cutting-
edge technologies, enhance external cooperation, proactively carry out innovative business cooperation in
the global market, and actively seek opportunities for international expansion of cutting-edge technologies
and products through licensing-in, cooperative development and other means. By focusing on its
advantageous fields, the Company will also strive to realize product iteration, build its technology platform,
and improve the construction of product portfolio in its core and advantageous fields, thus achieving long-
term sustainable development.
2. Sales Center
The key work deployments in marketing of prescription drugs are as follows: 1. Strengthen team building and
improve comprehensive quality through expanding and reinforcing the sales team of hospital channels and the
sales team of OTC channels, attracting excellent talents to join the sales team, making brand building a goal,
and enhancing the practical capability and comprehensive quality of marketing teams nationwide; 2. Continue
to strengthen integration of terminal resources, focus on establishing national benchmark areas, benchmark
hospitals and benchmark sales teams, include key hospitals above grade II in appraisal system, and
comprehensively enhance the coverage and fulfillment rate of evaluation indicators; 3. Make continuous efforts
in commerce, production, end-users and other links, rapidly increase market share and raise brand awareness
in all aspects; 4. Continue to advance construction of digital marketing platform and support for end-user market
activities, effectively combine online and offline methods, and enhance in-depth brand recognition among
doctors and patients; 5. Follow up in real time national medical reform-related policies, strengthen clinical and
pharmacoeconomic research of launched products , and actively respond to medical insurance policy
adjustments and volume-based procurement.
In terms of marketing and promotion of APIs and intermediates, the Company will further strengthen
construction of sales team, make full use of OKR and strengthen management by objectives, to build a vigorous
and highly efficient sales team; continue to deepen cooperation with global strategic customers, pursue further
development in segments, actively develop customer resources, maintain partnership, give full play to the
strength of the company brand, and establish a long-term, stable and win-win cooperation model with strategic
partners. Moreover, the Company will build good brand reputation in global market through close cooperation
with world-class enterprises. In addition, the Company will pay close attention to changes in exchange rates
and market conditions and promptly adjust sales strategies. The Company’s pet formulation product,
imidacloprid moxidectin drops, was launched in 2022. Considering the characteristics and promising
development prospects of animal health products-related business, the Company and our controlled subsidiary
Livzon Group jointly invested in the establishment of a joint venture, aiming at integrating the advantages of
both sides in the fields of R&D, production, brand promotion, online and offline omni-channel marketing, and
further accelerating the business plannings and enhancing efforts of promotion in the field of animal health care.
It is conducive to reinforce and enhance the Company’s inherent advantages in the field of animal health care
APIs and comprehensive competitiveness of business, and enter the rapidly developing consumer market of
animal health care formulations.
Health care products, as the Company’s first business segment developed, are attached great importance to the
Company's entire marketing strategies. In the future, the Group will implement digital marketing system for
increasing the on-line sale; meanwhile, strengthening the “online + offline” synergy to upgrade the offline
marketing model. We will continue to promote organizational structure reform of offline channels, channel in-
depth distribution and integration of key chains, and strengthen the sales empowerment of offline channels
through market resources empowerment, “Menopause Experts’ Views” and chain live-streaming. We will
continue to promote digital marketing system, attract off-site drainage and enhance on-site linkage, while we
deeply conduct big sales events and deliver festival gift boxes to drive online sales. In terms of content
marketing, we expand the KOL cooperation, continue to break through audience boundaries from vertical KOL


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Joincare Pharmaceutical Group                                                                Annual Report 2022


to non-vertical KOL, constantly expanding brand exposure. In terms of brand marketing and building, we will
continue to deepen the cooperation with industry associations and professional forums, strengthen the
professional building of brands, and carry out corresponding joint cooperation in platform promotion and
festival marketing to expand brand exposure and enhance brand sales. In addition, we will continue to increase
investment in user operations, and have established a special user operation team to attract, activate and operate
users with Wecom as the carrier, improve the WeChat digital mall, loyalty points and content operation system,
cultivate original users through user operation, and develop loyal fans belonging to the brand.
3.Production Center
On the production side, the Company will continue to strengthen internal operation management, enhance
the linkage of production, supply and sales plans and improve the operational efficiency of the supply
chain; continue to strengthen quality management throughout the life cycle, attach great importance to the
quality control of products and the effective operation of the quality system to prevent major quality and
safety incidents; further deepen the promotion of lean production, promote the construction of green
energy projects and continue to enhance production efficiency and the domestic driver of energy saving,
emission reduction and green environment protection; actively adopt intelligent technology to optimize
the production process, achieve cost reduction and efficiency enhancement, and further enhance the
competitive edge of core products.
4.Functions and strategies
In 2023, in respect of function management, the major tasks are as follows: firstly, we will further improve
the Company’s organizational structure and its set-up, and comprehensively promote lean management to
reduce costs and improve efficiency; secondly, we will continue to promote the construction of corporate
culture, strengthen the publicizing and following of the corporate culture among the Group and its
subsidiaries, and enhance corporate cohesion and centripetal force; thirdly, we will continue to strengthen
the construction of talents and systems, and improve the objective management system of OKR and KPI
in parallel; fourthly, we will actively practice corporate social responsibility, strive to improve corporate
governance and promote high-quality and sustainable development of the Company; fifthly, we will
actively leverage on our the advantages of internal and external resources to enhance the Group’s brand
influence.


(IV) Potential risks
√ Applicable    □ N/A
1. Risks of changes in industrial policies
The pharmaceutical manufacturing industry is significantly affected by changes in industrial policies. The
pharmaceutical industry will face great challenge in development in the future with continuous deepening
of medical reform, advancement of supply-side structural reform in the industry, revision of Drug
Administration Law, acceleration of consistency evaluation of generic drugs, adjustment of the new
edition of Medical Insurance Catalogue, expansion of volume-based procurement, and other industrial
policies that have been successively launched. In July 2022, the Company’s key product Meropenem for
Injection (注射用美罗培南) was selected in the seventh batch of volume-based procurement organized
by the PRC Government. This volume-based procurement was implemented in November 2022 and will
have a great impact on the sales price and market share of this product.
Response measures: The Company will pay close attention to industry dynamics and reform, cope with
major changes in policies of the pharmaceutical industry through early layout, transformation, and
compliance, and actively strengthen new product R&D and innovation and constantly improve its core
competitive strengths. Meanwhile, the Company is actively engaged in the access to the national


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Joincare Pharmaceutical Group                                                           Annual Report 2022


reimbursement drug list and negotiation and continue to increase the coverage of hospitals and sales, to
realize the objective of “price for quantity”, so as to reduce the impact of price adjustment on the
Company’s steady growth. Moreover, the volume-based drug procurement is becoming a regular practice.
In the face of the seventh batch of volume-based drug procurement and the possible impact on the business
performance of the Company, the Company will continue to strengthen innovation and improve its
competitiveness, to ensure sound operation. With the Company’s new high-barrier complex formulation,
represented by inhalation formulations appearing on the market one after another, commercialization will
gradually enter a stable contribution period. The Company’s product structure will be further optimized,
and the reliance on a single product will also gradually reduce. The Company will make continued efforts
to innovate and develop innovative medicines and high-barrier complex formulation with high added value
that are urgently needed for clinical research, explore the types of existing products with market potential
and technical barriers, actively reevaluate key medicines after their marketing and assess the consistency
of relevant medicines, continuously optimize the product structure, and actively explore and expand
overseas markets.
2. Market risk
With advancement of supply-side structural reform in the pharmaceutical manufacturing industry and two
invoice policy in circulation domain, pharmaceutical market structure is deeply changed. With the gradual
standardization and centralization of the market, competition in the pharmaceutical industry becomes
increasingly fierce. Affected by increasingly stricter drug regulation, policy-based drug price reduction,
price cutting during bidding, medical insurance premium control, and minimum procurement commitment
of the pharmaceutical industry in current stage, bid winning price of drugs will be further lowered,
competition among enterprises in the industry will be intensified, and price war will occur frequently, thus
the Company will be at the risk of drug price reduction.
Response measures: The Company will establish a more reasonable market system through strict
compliance operation so as to maintain its dominant position and core competitive strengths, and ensure
that it can achieve sustainable and steady development and improve its profitability by reinforcing
marketing. Meanwhile, the Company will offset the impact of product price reduction by means of price
supplement based on quantity, and optimize technical process and reduce production costs through internal
exploration and transformation. Moreover, the Company will speed up the R&D and marketing of new
products, spread risks of the Company while expanding the range of existing products in segment markets,
improve sales and form new profit growth point by increasing product varieties in the future.
3. Risk of safety and environmental protection
The Company is an integrated pharmaceutical manufacturing enterprise. During production, it implements
relevant chemical synthesis process and uses a large number of acid and alkali and other chemical
components, which are inflammable, explosive, toxic, irritant and corrosive, and have hidden hazards of
fire, explosion and poisoning, posing certain risks to the production and operation of the Company. As
environmental protection policies and regulations have been constantly issued in recent years,
environmental protection standards have become more stringent, and the state has strengthened its control
over pollutants, risks of environmental protection of the Company are increasing.
Response measures: The Company has always obeyed the safety work concept of “Putting People First”
and the guideline of “Safety First, Precaution Crucial and Comprehensive Treatment”. It will strengthen
the construction of safe production infrastructure and ensure a sound environment for safe production of
the Company through regular internal audit of safety and environment systems as well as employee safety
education and training. The Company will carry out discharge after treatment and reaching standards in
accordance with environmental protection provisions, actively accept supervision and inspection of
environmental protection authorities, and try to reduce emission and increase expenditures in



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Joincare Pharmaceutical Group                                                            Annual Report 2022


environmental protection by improving production process and promptly updating environmental
protection technology.
4. Risk in price and supply of raw materials
There is a larger fluctuation in the supply price of some raw materials of the Company due to changes in
material prices, especially the materials of traditional Chinese medicine, causing greater volatility or rise
in production costs of the Company. Meanwhile, the quantity and category of raw material suppliers of
the Company are various, thus quality of final products of the Company will be directly affected by the
selection of raw material suppliers and the guarantee and control of quality of raw materials.
Response measures: In terms of selection of suppliers, the Company will conduct an open tendering and
bidding based on the principle of selecting qualified suppliers, strengthen audit of suppliers, and eliminate
the adulteration of adverse suppliers. The Quality Assurance Department and Supply Department of the
Company will directly conduct process control of products provided by suppliers of key raw materials and
carry out quality inspection and control of final products
5. Risk of R&D for new drugs
New drug R&D is characterized by high input, high risk and long period. The State has frequently issued
drug R&D related policies in recent years to further enhance approval work requirements of new drugs
for marketing, thus bringing certain risks for new drug R&D of the Company. Meanwhile, promotion of
drugs after marketing is affected by national regulations, industry policies, market environment and
competitive intensity, causing that income obtained after marketing of new drugs cannot reach the
expected income, making the Company at risk of product R&D.
Response measures: The Company will focus on innovative medicines and high-barrier complex
formulation, pay attention to unmet clinical needs, and continuously invest in innovative research and
development. The Company will further improve the R&D and innovation systems, introduce and develop
high-end talents, proactively carry out cooperation and introduction of overseas innovative medicines,
strengthen market research and evaluation of varieties, reinforce the process regulation and risk
management of the initiation of R&D projects, and concentrate efforts and make key breakthroughs in the
R&D of core products. At the same time, the Group’s advantages in APIs will be fully utilized to reinforce
the integration of API and drug formulations to ensure the long-term sustainable development of the
Company.

(V) Others
□Applicable √N/A

VII. Information not disclosed according to guidelines due to inapplicability of the standard,
involving state secrets or trade secrets or other reasons, and notes on relevant reasons
□Applicable √N/A




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Joincare Pharmaceutical Group                                                           Annual Report 2022



                                Chapter 4 Corporate Governance

I. Corporate Governance
√Applicable □N/A
The Company is in compliance with the corporate governance requirements applicable to it as a PRC
public company listed on the Shanghai Stock Exchange in all material aspects, including but not limited
to the Company Law, the Securities Law, the Guidelines for Corporate Governance of Listed
Companies, and the Rules Governing the Listing of Stocks on Shanghai Stock Exchange. During the
Reporting Period, the Company continued to improve its corporate governance structure, strengthen
information disclosure management and enhance investor relations management and internal control to
standardize the operation of the Company.
1. Shareholders and General Meetings
During the Reporting Period, 1 annual general meeting and 4 extraordinary general meetings were held
by the Company. The Company convened and held general meetings in strict compliance with the Articles
of Association, Rules of Procedure for the General Meetings and other relevant regulations to ensure that
resolutions can be made at general meetings based on fairness and openness, thereby safeguarding the
rights and interests of shareholders. In addition, the Company made full use of modern information
technology such as online voting to ensure that all shareholders, particularly minority shareholders, can
attend general meetings and exercise their rights to know and participate in decision making in the most
convenient and fastest way.
2. Controlling shareholders and the listed company
The Company is able to carry on its business and operations independently. In terms of business, personnel,
assets, organizations and finance, the Company performed management and accounting independently
from the controlling shareholders of the Company. The controlling shareholders of the Company have
exercised their rights and assumed their obligations in strict compliance with the laws and regulations, and
have never directly or indirectly interfered with the decision-making or business activities of the Company
without authorization of the general meeting. The Company has formulated the Management Policy of
Joincare Pharmaceutical Group Industry Co., Ltd. for Preventing the Controlling Shareholders or De Facto
Controller and Other Related Parties from Appropriating Funds of the Company, and has established a
long-term mechanism to prevent the controlling shareholders or de facto controller and their related parties
from using funds of the listed company or damaging the interests of the listed company. During the
Reporting Period, there was no circumstance where the Company's controlling shareholders, de facto
controller, and their related parties embezzled assets of the Company or damaged the interests of the
Company and minority shareholders.
3. Directors and the Board
During the Reporting Period, the Company held 14 Board meetings in multiple ways, including on-site
meeting, voting through electronic means and the combination of on-site meeting and electronic means,
providing convenience for the attending directors. During the Reporting Period, the Board of the Company
performed its duties actively and effectively in strict compliance with the relevant regulations, including
the Company Law, the Articles of Association, and the Rules of Procedure for the Board Meetings.
The Board of the Company comprises a total of 9 directors, including 4 independent directors who are
legal and financial professionals and provide constructive advice for the effective, standard governance
and decision-making on major policies of the Company. Besides, five special committees are set up under
the Board of the Company, namely the Audit Committee, the Remuneration Committee, the Strategy
Committee, the Nomination Committee, and the Corporate Social Responsibility Committee. These
committees assist the Board in performing its decision-making and supervision functions and give full

                                                    78
Joincare Pharmaceutical Group                                                             Annual Report 2022


play to their expertise, so as to ensure the legality, scientificity, and correctness of decisions made by the
Board.
During the Reporting Period, the Company convened, held and voted at the board meetings in accordance
with the Rules of Procedure for the Board Meetings, and all directors of the Company have attended
meetings including the board meetings and general meetings in a conscientious, responsible and honest
manner, actively participated in relevant business training, familiarized themselves with relevant laws and
regulations, and clarified the rights, obligations and responsibilities of directors.
4. Supervisors and the Supervisory Committee
During the Reporting Period, the Company held 12 meetings of the Supervisory Committee for review of
the periodic report, option exercise, special report on fund raising, and other matters of the Company. The
Supervisory Committee of the Company is comprised of three supervisors, including one employee's
representative. During the Reporting Period, the Supervisory Committee of the Company performed its
duties in accordance with the law, supervised the duty performance of directors and senior management
of the Company, carried out regular inspections on the financial position of the Company, and focused on
significant investments of the Company, fully protecting the interests of the Company and all shareholders.
5. Performance evaluation and incentive restraint mechanism for senior management
The appointment and dismissal of and reward and punishment for senior management of the Company are
performed in strict accordance with the relevant laws, regulations, and the Articles of Association. The
Company has established the selection, appointment and performance assessment criteria and the
remuneration decision-making procedure for the senior management. The Nomination Committee of the
Company provided appropriate candidates for directors and senior management in accordance with the
law, and submitted the list of candidates to the Board of the Company for review. The Remuneration
Committee of the Company, pursuant to the regulations such as the Management Policy on the
Remuneration and Performance Assessment of Senior Management, determined the result of performance
assessment of senior management based on the completion of business objectives of the Company and
work objectives of the senior management in 2022. Based on the result of performance assessment, the
performance bonus and remuneration of senior management in 2022 were determined and submitted to
the Board of the Company for review and resolution.
6. Investor relations
The Company has always attached great importance to communication and exchange with investors. The
Board designated departments and personnel to manage information disclosure and investor relations,
enhance communication with minority shareholders, answer questions from shareholders on the
production, management and operation of the Company, and listen earnestly to the suggestions and advice
of shareholders on the strategy and development of the Company. Without violating regulations, the
Company satisfied to the maximum extent the information needs of investors for the sustainable and
healthy development of the Company.
7. Information disclosure and transparency
The Company disclosed information in a timely, accurate, authentic and complete manner in strict
compliance with the relevant regulations, including the Company Law, the Rules Governing the Listing
of Stocks on Shanghai Stock Exchange, the Articles of Association, and the Information Disclosure
Management Bylaws. The Company designated the Board Secretary to manage information disclosure,
receive visitors, answer questions consulted, contact shareholders, and provide investors with the
information publicly disclosed by the Company. The Company is able to disclose information in an
authentic, accurate, complete and timely manner in accordance with the laws, regulations, and the Articles
of Association, and is able to ensure equal access to information for all shareholders.




                                                     79
Joincare Pharmaceutical Group                                                            Annual Report 2022


8. Stakeholders
The Company has fully respected the legitimate rights and interests of stakeholders, including banks, other
creditors, employees, consumers, suppliers and communities, and has extended communication and
cooperation with such stakeholders based on mutual benefit, so as to jointly promote the sustained and
healthy development of the Company and protect the interests of public shareholders.
During the Reporting Period, the Company did not provide undisclosed information to its substantial
shareholders or de facto controller, and the substantial shareholders and de facto controller of the Company
did not interfere with the production, operation and management of the listed company. Overall, no
corporate governance irregularities were found.
The corporate governance of the Company complies with the Company Law and relevant regulations
issued by the CSRC. Achieving good corporate governance is a long journey, which requires continuous
improvement. The Company will continue to timely update and improve its internal governance system
in accordance with relevant regulations, discover and solve problems in a timely manner, and strengthen
internal management, so as to promote standard operation and corporate governance as well as advance
the steady and healthy development of the Company.
9. Establishment and implementation of insider registration management system for insider
information
The Resolution relating to Amendment of the Insider Registration Management System for Inside
Information of Joincare Pharmaceutical Group Industry Co., Ltd. was revised and approved at the 8th
meeting of the 8th session of the Board of the Company, with a view to strengthening the confidentiality
of inside information, maintaining the principles of openness, fairness and justice for the Company's
information disclosure, and protecting the legitimate rights and interests of investors. During the Reporting
Period, the Board Office of the Company was responsible for the management of inside information of
the Company. It is stipulated that the documents and data reported and transmitted externally and other
information involving inside information and information disclosure shall be reviewed and approved by
the Board or the Board Secretary. When preparing periodic reports and planning significant matters, the
Company performed inside information registration timely, and reminded the insiders by mail or phone
not to deal with shares of the Company during the sensitive period. Through self-inspection, it was found
that there was no circumstance where the insiders dealt with shares and derivatives using inside
information of the Company during the Reporting Period.


Whether there are any material deviations of the Company's corporate governance from laws,
administrative regulations and CSRC regulations on the governance of listed companies; If any,
give the reasons.
□Applicable √N/A

II. Measures taken by the controlling shareholder and de facto controllers to ensure the
independence of the Company's assets, personnel, finance, organization, business, in addition to
solutions, work schedules and follow-up work plans adopted to enhance the independence of the
Company
□Applicable √N/A

Engagement in the same or similar business as the Company by controlling shareholders, de facto
controllers and other units under their control, and the influence of horizontal competition or major
changes in horizontal competition on the Company, countermeasures taken, progress and follow-up plan
□Applicable √N/A

III. Introduction of General Meetings


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Joincare Pharmaceutical Group                                                               Annual Report 2022


                                    Query index of
                                    the designated
                       Date of                       Disclosure
  Meeting session                     website for                              Meeting resolution
                       meeting                          date
                                    publishing the
                                      resolution
                                                                   Eight (8) resolutions were considered and
                                                                   approved, including the Resolution on
                                                                   Changing Certain Projects Invested with
                                                                   Proceeds, the Resolution on Revision of
                                                                   Certain Clauses of Articles of Association and
 2022 First
                     11 February                     12 February   the Resolution on Revision of Certain Clauses
 Extraordinary                      www.sse.com.cn
                        2022                         2022          of the Rules of Procedure for the Board
 General Meeting
                                                                   Meetings. See the Announcement on
                                                                   Resolutions of Joincare Pharmaceutical Group
                                                                   Industry Co., Ltd. at the 2022 First
                                                                   Extraordinary General Meeting (Lin 2022-
                                                                   014) for details
                                                                   Fourteen (14) resolutions were considered and
                                                                   approved, including the 2021 Annual Work
                                                                   Report of the Supervisory Committee, the
                                                                   Resolution on Election of Mr. Xing Zhiwei as
 2021 Annual                                         19 May        Supervisor of the Company and 2021 Annual
                     18 May 2022    www.sse.com.cn
 General Meeting                                     2022          Work Report of the Board of Directors. See the
                                                                   Announcement on Resolutions of Joincare
                                                                   Pharmaceutical Group Industry Co., Ltd. at the
                                                                   2021 Annual General Meeting (Lin 2022-051)
                                                                   for details
                                                                   Ten (10) resolutions were considered and
                                                                   approved, including the Resolution on the
                                                                   Company’s Issuance of GDRs, listing on the
                                                                   SIX Swiss Exchange and Conversion into a
                                                                   Joint Stock Limited Company Offering Shares
                                                                   Overseas, the Resolution on the Plan for the
 2022 Second
                                                                   Company’s Issuance of GDRs and Listing on
 Extraordinary        8 July 2022   www.sse.com.cn   9 July 2022
                                                                   the SIX Swiss Exchange and the Resolution on
 General Meeting
                                                                   Report on the Utilization of the Proceeds
                                                                   Previously Raised by the Company. See the
                                                                   Announcement on Resolutions of Joincare
                                                                   Pharmaceutical Group Industry Co., Ltd. at the
                                                                   2022 Second Extraordinary General Meeting
                                                                   (Lin 2022-077) for details
                                                                   The Resolution on 2022 Share Options
                                                                   Incentive Scheme (Draft) and its Summary,
                                                                   the Resolution on the Administrative
                                                                   Measures for Appraisal System of the 2022
                                                                   Share Options Incentive Scheme of the
                                                                   Company and the Resolution on the General
 2022 Third
                      29 August                      30 August     Meeting for Granting Mandate to the Board to
 Extraordinary                      www.sse.com.cn
                        2022                         2022          Deal with Matters Regarding the Share
 General Meeting
                                                                   Options Incentive Scheme were considered
                                                                   and approved. See the Announcement on
                                                                   Resolutions of Joincare Pharmaceutical Group
                                                                   Industry Co., Ltd. at the 2022 Third
                                                                   Extraordinary General Meeting (Lin 2022-
                                                                   095) for details
                                                                   Four (4) resolutions were considered and
                                                                   approved, including the Resolution on
                                                                   Repurchase of Shares of the Company through
                                                                   Centralized Bidding Transactions, the
                                                                   Resolution on the General Meeting for
 2022 Fourth                                         19            Granting Mandate to the Board to Deal with
                     18 November
 Extraordinary                      www.sse.com.cn   November      Matters Regarding the Repurchase and the
                         2022
 General Meeting                                     2022          Resolution on Change in Registered Capital of
                                                                   the Company. See the Announcement on
                                                                   Resolutions of Joincare Pharmaceutical Group
                                                                   Industry Co., Ltd. at the 2022 Fourth
                                                                   Extraordinary General Meeting (Lin 2022-
                                                                   134) for details


                                                     81
                Joincare Pharmaceutical Group                                                                                  Annual Report 2022




                Holders of preferred shares with resumed voting rights requesting to hold extraordinary general
                meeting
                □ Applicable √ N/A

                Explanations of General Meetings
                □ Applicable √ N/A

                IV. Information on directors, supervisors and senior management
                (I) Changes in shareholding and remuneration of current directors, supervisors, and senior
                management and those left the Company during the Reporting Period
                √Applicable □N/A
                                                                                                Unit: shares
                                                                                                                                     Total pre-tax
                                                                                                                                     remuneration
                                                                                                                                                      Receive any
                                                                                                                                        received
                                                                              Number        Number                                                   remuneration
                                                                                                          Change in                     from the
                                                  Start date                  of shares     of shares                                                  from any
                                                               End date of                               shareholding   Reason for     Company
  Name         Position (Note)     Gender   Age     of the                   held at the   held at the                                               related party
                                                                the tenure                                during the     change        during the
                                                   tenure                    beginning     end of the                                                    of the
                                                                                                             year                      Reporting
                                                                             of the year      year                                                    Company or
                                                                                                                                         Period
                                                                                                                                                          not
                                                                                                                                      (RMB Ten
                                                                                                                                       thousand)
Zhu                                               28 August    27 August
            Chairman               Male     61                                                                                             334.09        No
Baoguo                                            2021         2024
Liu                                               28 August    27 August
            Vice Chairman          Female   54                                                                                             347.98        No
Guangxia                                          2021         2024
                                                  28 August    27 August                                                Equity
Yu Xiong    Director, President    Male     62                                 660,000       800,000         140,000                       360.00        No
                                                  2021         2024                                                     incentive
            Director, Vice
Qiu                                               28 August    27 August                                                Equity
            President, Chief       Male     52                                 537,409       717,409         180,000                       224.93        Yes
Qingfeng                                          2021         2024                                                     incentive
            Financial Officer
            Director, Vice                        28 August    27 August                                                Equity
Lin Nanqi                          Male     41                               1,051,040     1,291,040         240,000                       224.93        Yes
            President                             2021         2024                                                     incentive
                                                  28 August    27 August
Cui Liguo   Independent Director   Male     53                                                                                              11.54        No
                                                  2021         2024
                                                  28 August    27 August
Huo Jing    Independent Director   Female   47                                                                                              11.54        No
                                                  2021         2024
                                                  28 August    27 August
Qin Yezhi   Independent Director   Male     49                                                                                              11.54        No
                                                  2021         2024
                                                  28 August    27 August
Peng Juan   Independent Director   Female   59                                                                                              11.54        No
                                                  2021         2024
            Chairman of
Yu                                                28 August    27 August
            the Supervisory        Male     55                                                                                              70.13        No
Xiaoyun                                           2021         2024
            Committee
Peng                                              28 August    27 August
            Supervisor             Female   61                                   38,043       38,043               0                         4.80        No
Jinhua                                            2021         2024
                                                                                                                        Purchase
Xing                                              18 May       27 August                                                from the
            Supervisor             Male     37                                   61,100             0        -61,100                       168.88        No
Zhiwei                                            2022         2024                                                     secondary
                                                                                                                        market
Xie                                               28 August    18 May
            Supervisor(resigned)   Male     66                                   75,442       75,442               0                        38.75        No
Youguo                                            2021         2022
            Vice President,
Zhao                                              28 August    27 August                                                Equity
            Secretary to the       Male     48                                 588,000       768,000         180,000                     2,010.58        No
Fengguang                                         2021         2024                                                     incentive
            Board
  Total               /              /       /        /             /        2,949,934     3,689,934         740,000    /                                  /

                Notes: 1. Mr. Zhu Baoguo serves as the chairman of Livzon Group, a controlled subsidiary of the Company; and Mr. Yu
                Xiong and Mr. Qiu Qingfeng serve as non-executive directors of Livzon Group. The remuneration listed above does not
                include the part paid by Livzon Group. Please refer to Livzon Group's 2022 Annual Report for details.
                     2.Upon the consideration and approval at the 2021 annual general meeting of the Company, Mr. Xing Zhiwei has
                been a Supervisor of the Company with effect from 18 May 2022, after that there was not any change in shareholding.

                         Name                                               Main work experience
                                    Male, born in 1962, with a bachelor's degree. He was the director of Henan Xinxiang Waterborne Resin
                                    Research Institute, vice chairman and general manager of Henan Feilong Fine Chemical Products Co.,
                  Zhu Baoguo
                                    Ltd., and had been the general manager and vice chairman of the Company since 1992. He is currently
                                    the chairman of the Company and the chairman of Livzon Pharmaceutical Group Inc. Mr. Zhu Baoguo

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Joincare Pharmaceutical Group                                                                    Annual Report 2022


                is a shareholder of Shenzhen Baiyeyuan Investment Co., Ltd., a controlling shareholder of the Company,
                and is the de facto controller of the Company.
                Female, born in 1969, with a college degree. She was the manager of the Advertising Department of
                CCTV International Corporation Shenzhen, deputy general manager and director of the Company, and
 Liu Guangxia   the vice chairman of Livzon Group. She is currently the vice chairman of the Company. Ms. Liu
                Guangxia is a shareholder of Shenzhen Baiyeyuan Investment Co., Ltd., a controlling shareholder of
                the Company, and is the spouse of Mr. Zhu Baoguo, the de facto controller of the Company.
                Male, born in 1961, researcher. He graduated from the Department of Chemistry of Fudan University
                with a bachelor of science degree in July 1984. In 1999, he received the special government allowance
                from the State Council. In 2004, he studied at KU Leuven in Modern Enterprise Management. From
                July 2005 to January 2006, he worked as a senior visiting scholar at California State University,
                Northridge. Since 2016, he had been the vice president of the Company. He serves currently as director
                and president of the Company, director of Livzon Group, chairman of Shanghai Frontier and Haibin
                Pharma, independent director of Tianjin Tianyao Pharmaceuticals Co., Ltd. and Sichuan Biokin
                Pharmaceutical Co., Ltd., director of Shanghai Huatai Investment Development Co., Ltd., honorary
                director of Chinese Pharmaceutical Association, honorary chairman of Pharmaceutical Engineering
 Yu Xiong
                Specialized Committee, honorary director of Shanghai Society of Chemistry and Chemical Industry,
                and adjunct professor of East China University of Science and Technology. He was formerly the vice
                president of China State Institute of Pharmaceutical Industry, chemistry department director and vice
                president of Shanghai Institute of Pharmaceutical Industry, chairman of Shanghai Techwell
                Biopharmaceutical Co., Ltd., legal person of National Shanghai Center for New Drug Safety Evaluation
                and Research, and general manager and chairman of Sinopharm Yangzhou VAC Biological
                Engineering Co., Ltd. He was also the person in charge of the comprehensive new drug research and
                development platform under the national key project of “new drug creation”(Shanghai Institute of
                Pharmaceutical Industry) and the technical chief of rolling projects under the 12th Five-Year Plan.
                Male, born in 1971, with an executive master of business administration degree from China Europe
                International Business School, member of Chinese Institute of Certified Public Accountants (non-
                practicing). He worked at Tianjin No.1 Machine Tool Works. Since 1996, he had served successively
 Qiu Qingfeng   as the finance personnel, finance supervisor, finance manager, deputy general manager of the Company,
                and the general manager, board secretary, and president of the Company. He is currently the director,
                vice president and chief financial officer of the Company and a non-executive director of Livzon
                Pharmaceutical Group Inc.
                Male, born in 1982, with a bachelor of engineering degree. He was formerly the workshop supervisor
                of Chongqing Daxin Pharmaceutical Co., Ltd., the workshop manager, production director and deputy
 Lin Nanqi      general manager of Livzon Group Xinbeijiang Pharmaceutical Manufacturing Inc., and the general
                manager of Jiaozuo Joincare Bio Technological Co., Ltd., a wholly-owned subsidiary of the Company.
                He is currently the director and vice president of the Company.
                Male, born in 1970, with a master of laws degree. He is the founding partner and director of
                Management Committee of Beijing Guantao Law Firm. He is currently an independent director of the
 Cui Liguo      Company, APT Satellite Holdings Limited (security code: 01045), CNNC International Ltd. (security
                code: 02302), Frontier Services Group Ltd. (security code: 00500), China Coal Xinji Energy Co., Ltd.
                (security code: 601918) and Beijing Life Insurance Co., Ltd.
                Female, born in 1976, with a bachelor's degree. She is a member of All China Lawyers Association and
                Tencent Guangdong Real Estate Think Tank. She was a specially invited lawyer by chinacourt.org,
                9ask. cn, 66law.cn, Southern Metropolis Daily, and Shenzhen Evening News. Since 2007, she has been
                the lawyer and partner of Guangdong Sun Law Firm. She was a member of Real Estate Specialized
 Huo Jing
                Committee of Shenzhen Lawyers Association, and served successively as permanent legal adviser to
                many companies, fully responsible for the review of corporate legal affairs, drafting and amendment of
                economic contracts, and issuance of legal opinions, with extensive litigation experience for various
                types of cases. She is currently an independent director of the Company.
                Male, born in 1974, with a bachelor's degree, a practicing member of Chinese Institute of Certified
                Public Accountants and China Certified Tax Agents Association, and a non-practicing member of China
                Certified Public Valuers Association. He successively served as auditor of Shenzhen Zhengfeng Lifu
 Qin Yezhi
                Accounting Firm, partner of Shenzhen Jinzheng Accounting Firm, and partner of Asia Pacific (Group)
                CPAs (Special General Partnership). From 2014 to date, he has served as partner of China Shu Lun Pan
                Certified Public Accountants LLP. He is currently an independent director of the Company.
                Female, born in 1964, doctor and doctoral supervisor. From 1997 to date, she has been an associate
                professor at the Department of Accounting of Antai College of Economics and Management in
                Shanghai Jiao Tong University, covering research areas of digital finance, green finance, marketing
                audit, and corporate governance. She is currently an independent director of the Company. She
                successively served as instructor at the Department of Accounting of School of Economics and
 Peng Juan
                Management in Shanghai Maritime University, and director of Executive Education Center of Antai
                College of Economics and Management in Shanghai Jiao Tong University. She is currently the president
                and training supervisor of Shanghai Cost Research Society of Shanghai Jiao Tong University, adviser
                of China Financial Cloud Institute, a member of Behavioral Science Council, a member of Finance and
                Accounting Association of Shanghai Jiao Tong University, and a member of Green Finance Center of


                                                         83
Joincare Pharmaceutical Group                                                                         Annual Report 2022


                Shanghai Environment and Energy Exchange. She served concurrently as independent director of
                Shanghai Sunglow Packaging Technology Co., Ltd. (stock code: 603499), Dynamiker Biotechnology
                (Tianjin) Co., Ltd. and Shanghai Sunmi Technology Co., Ltd.
                Male, born in 1968, with a bachelor's degree, and an MBA degree from University of Greenwich. He is
                a senior engineer and high-level professional talent of Shenzhen. He worked for Henan Institute of
                Traditional Chinese Medicine. From December 1992 to date, he has served successively as technical
 Yu Xiaoyun
                manager of the Company, government affairs manager of Institute of Traditional Chinese Medicine,
                and vice president of the Institute. He is currently the adviser of the Institute and chairman of the
                Supervisory Committee of the Company, and also a standing member of China Healthcare Association.
                Female, born in 1962, with a college degree. She served as technical data processor at State-owned
                272nd Plant of Ministry of Nuclear Industry and accountant of the staff hospital of the Plant, teacher of
                Hengyang Radio & TV University, and finance manager of Shenzhen New Era Industrial City Industrial
 Peng Jinhua    Co., Ltd. She joined the Company in March 1994, and served successively as finance supervisor,
                manager of planning and finance department, manager of finance department, manager of tax
                department, administration manager, and general manager assistant. She is currently a supervisor of the
                Company.
                Male, born in 1986. He graduated from Sichuan University majoring in light industry biotechnology
                with a bachelor's degree. He currently serves as the deputy director of the Center of the Production
                Management and a supervisor of the Company, the general manager and vice president of the
                Company’s subsidiary Jiaozuo Joincare Bio Technological Co., Ltd. and a director and the general
 Xing Zhiwei
                manager of the Company’s subsidiary Henan Province Joincare Biopharmaceutical Research Institute
                Co., Ltd. He served successively as workshop supervisor and workshop manager of Livzon Group
                Xinbeijiang Pharmaceutical Manufacturing Inc., and workshop manager, production director and
                deputy general manager of Jiaozuo Joincare Bio Technological Co., Ltd.
                Male, born in 1975, with a bachelor of economics degree and master of science degree, member of
                Jiusan Society. He was formerly the secretary to president of Shenyang Pharmaceutical University,
                council secretary and office director of Shenzhen Research Center of Traditional Chinese Medicine and
 Zhao           Natural Products, and assistant to director of Chinese Medicine Laboratory of Research Institute of
 Fengguang      Tsinghua University in Shenzhen. Since August 2011, he served successively as manager of project
                research and management department of the institute of the Company, deputy head and project research
                director of the institute of the Group, and director of the controlling subsidiary Shanghai Frontier. He is
                currently the vice president and board secretary of the Company

Explanations of other relevant information
√Applicable □N/A
On 22 April 2022, the Company held the ninth meeting of the eighth session of the Supervisory Committee
to consider and approve the Resolution on Nominating Mr. Xing Zhiwei as a Candidate for Supervisor of
the Supervisory Committee, and the Supervisory Committee agreed to nominate Mr. Xing Zhiwei as a
candidate for Supervisor of the eighth session of the Supervisory Committee of the Company, and
submitted this resolution to the general meeting for consideration. On 18 May 2022, the Resolution on
Election of Mr. Xing Zhiwei as Supervisor of the Company was considered and approved at the 2021
Annual General Meeting of the Company, pursuant to which Xing Zhiwei serves as the supervisor of the
Company for a term commencing from the date of consideration and approval at the General Meeting to
the date of expiry of the term of the eighth session of the Supervisory Committee.

(II) Posts held by current directors, supervisors, and senior management and those resigned during
the Reporting Period
1. Posts held at corporate shareholders of the Company
√Applicable □N/A
                                                                                                 End date
                                                                                 Start date of the
     Name        Corporate shareholder                 Posts held                                   of the
                                                                                      tenure
                                                                                                   tenure
 Zhu Baoguo      Baiyeyuan                 Chairman, General Manager           11 March 2014           /
 Liu Guangxia    Baiyeyuan                 Director                           21 January 1999          /
                 Mr. Zhu Baoguo, Chairman of the Company, directly holds 90% of shares in Baiyeyuan, and
                 Ms. Liu Guangxia, Vice Chairman of the Company, directly holds 10% of shares in
 Note
                 Baiyeyuan. Both of them are directors of Baiyeyuan, and Mr. Zhu Baoguo is the spouse of
                 Ms. Liu Guangxia.




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Joincare Pharmaceutical Group                                                                      Annual Report 2022


2. Posts held at other entities
√Applicable □N/A
                                                                                                           End date
                                                                                      Start date of the
    Name                     Other entities                       Posts held                                 of the
                                                                                      tenure
                                                                                                            tenure
               Shenzhen Federation of Industry and           Honorary Vice
                                                                                      November 2014            /
               Commerce                                      President
               Federation of Shenzhen Commerce               Director                 April 2015               /
                                                             Council Member,
    Zhu        TNC Greater China Council of Advisors                                  December 2012            /
                                                             Secretary General
   Baoguo
               The Paradise International Foundation         Director                 April 2015               /
               China Entrepreneur Club                       Council Member           April 2017               /
               Central China Management Company
                                                             Independent Director     May 2021                 /
               Limited
               Shanghai Society of Chemistry and
                                                             Honorary Director        October 2016             /
               Chemical Industry
               Tianjin Tianyao Pharmaceuticals Co., Ltd.     Independent Director     December 2016            /
               Shanghai Huatai Investment Development
                                                             Director                 May 2018                 /
               Co., Ltd.
               East China University of Science and
  Yu Xiong                                                   Adjunct Professor        July 2019                /
               Technology
               Sichuan Biokin Pharmaceutical Co., Ltd.       Independent Director     September 2019           /
               Pharmaceutical Engineering Specialized
               Committee of Chinese Pharmaceutical           Honorary Chairman        November 2019            /
               Association
               Chinese Pharmaceutical Association            Honorary Director        January 2022             /
               Jiaozuo Jinguan Jiahua Electric Power Co.,
                                                             Director                 November 2015            /
    Qiu        Ltd.
  Qingfeng     Jiangsu Baining Yingchuang Medical
                                                             Director                 November 2020            /
               Technology Co., Ltd.
               Jiaozuo Jinguan Jiahua Electric Power Co.,
  Lin Nanqi                                                  Director                 January 2022             /
               Ltd.
                                                             Founding Partner,
                                                             Director of
               Beijing Guantao Law Firm                                               February 1994            /
                                                             Management
                                                             Committee
               APT Satellite Holdings Limited (listed        Independent non-
                                                                                      July 2007                /
               overseas)                                     executive director
                                                             Independent non-
               CNNC International Ltd. (listed overseas)                              November 2008            /
                                                             executive director
               Frontier Services Group Ltd.(listed           Independent non-
  Cui Liguo                                                                           June 2020                /
               overseas)                                     executive director
               China Electronics Information Service Co.,
                                                             External Director        July 2016                /
               Ltd.
                                                                                                          December
               Essence Securities Co., Ltd.                  Independent Director     November 2016
                                                                                                            2022
               Beijing Life Insurance Co., Ltd.              Independent Director     March 2018              /
               CEC      Xinze     (Beijing)   Investment
                                                             External Director        May 2018                 /
               Management Co., Ltd.
               China Coal Xinji Energy Co., Ltd.             Independent Director     May 2019                 /
  Huo Jing     Guangdong Sun Law Firm                        Lawyer, Partner          June 2007                /
               China Shu Lun Pan Certified Public
               Accountants LLP (Special General              Partner                  July 2014                /
  Qin Yezhi    Partnership)
               Shenzhen Yongpeng CTA Firm (Special
                                                             Partner                  September 2013           /
               General Partnership)
                                                             Associate Professor of
               Antai College of Economics and
                                                             Department of
  Peng Juan    Management of Shanghai Jiao Tong                                       September 1997           /
                                                             Accounting, Doctoral
               University
                                                             Supervisor


                                                            85
Joincare Pharmaceutical Group                                                                     Annual Report 2022


                Kexin Development Co., Ltd., Shanxi         Independent Director          July 2016        June 2022
                                                                                                            August
                Zhejiang Dibay Electric Co., Ltd.           Independent Director        August 2016
                                                                                                             2022
                Jiangsu Pizhou Rural Commercial Bank        Independent Director      September 2016       July 2022
                Dynamiker Biotechnology (Tianjin) Co.,
                                                            Independent Director          July 2020            /
                Ltd.
                Shanghai Sunglow Packaging Technology
                                                            Independent Director        March 2022             /
                Co., Ltd.
                Shanghai Sunmi Technology Co., Ltd.         Independent Director         May 2022              /
                Shanghai Jiaopeng Technology Co., Ltd.      Supervisor                   July 2019             /
                Shanghai Jiaoshang Digital Technology
                                                            General Manager            December 2022           /
                Co., Ltd.
     Yu         Shenzhen Science and Technology
                                                            Review Expert             November 2022            /
   Xiaoyun      Innovation Commission
                Shenzhen Nanbei Shengying Industrial
                                                            Director                      July 2017
                Development Co., Ltd.
 Peng Jinhua
                Shenzhen      Xinfengfan    Technology
                                                            Supervisor                  August 2005
                Development Co., Ltd.
    Note        Not applicable


(III) Remuneration of directors, supervisors and senior management
√Applicable □N/A

                          The emolument of chairman and vice chairman of the Company shall follow the Resolutions
                          of the 2018 Second Extraordinary General Meeting of the Company, which is RMB3.25
                          million per year, with the individual income tax withheld and remitted by the Company in
                          accordance with the relevant provisions of the tax laws. On 29 March 2022 and 18 May 2022,
                          the Company convened the ninth meeting of the eighth session of the Board of Directors and
                          the 2021 Annual General Meeting, respectively, at which the Resolution on Adjusting the
                          Emolument of Independent Directors of the Company(《关于调整公司独立董事津贴的议
                          案》) was considered and approved, the emolument of each independent director shall be
                          adjusted to RMB10,000 (before tax) from RMB9,000 (before tax) per month, with the
                          individual income tax withheld and remitted by the Company in accordance with the relevant
                          provisions of the tax laws.
                          On 10 August 2021 and 28 August 2021, the Company convened the 39th meeting of the
                          seventh session of the Supervisory Committee and the 2021 Third Extraordinary General
                          Meeting, respectively, at which Resolution on Adjusting the Emolument of the Supervisors of
                          the Company( 《 关于调 整公 司监事津 贴的议 案》 ) was considered and approved, the
                          emolument of each supervisor shall be adjusted to RMB4,000 (before tax) per month from
 Decision-making          RMB3,000 (before tax) per month, with the individual income tax withheld and remitted by
 procedure regarding      the Company in accordance with the relevant provisions of the tax laws. During the Reporting
 remuneration of          Period, the remuneration received by supervisors is the wage based on the wage system of the
 directors, supervisors   Company plus the emolument paid to them.
 and senior
 management               The remuneration of senior management of the Company shall follow the resolution of the 52th
                          meeting of the 6th session of the Board of the Company. The annual basic remuneration of the
                          president, vice president and other senior management members during the term of office is
                          RMB2.60 million, RMB1.35 million and RMB1.20 million, respectively. In addition to the
                          basic remuneration, pursuant to the regulations such as the Management Policy on the
                          Remuneration and Performance Assessment of Senior Management (《高级管理人员薪酬及
                          绩效考核管理制度》), individual assessment shall be performed and performance-based
                          bonuses shall be paid according to the assessment result. In case of holding concurrent
                          positions, the highest remuneration among all positions shall prevail.
                          For the Company's directors who serve concurrently as a senior management member of the
                          Company, the remuneration received by them is equal to the wage paid according to their
                          position as a senior management member, and no directors’ emoluments are paid by the
                          Company.
                          On 16 January 2023, the Remuneration Committee under the Board of the Company convened
                          the 8th meeting of the 8th session of the Board, at which the Resolution on the 2022 Annual
                          Performance Assessment Result and Remuneration Distribution of Senior Management of the
                          Company (《关于公司高级管理人员 2022 年度绩效考核结果及薪酬分配的议案》) was

                                                          86
  Joincare Pharmaceutical Group                                                                      Annual Report 2022


                            considered and approved. It was agreed that the Company, pursuant to the regulations such as
                            the Management Policy on the Remuneration and Performance Assessment of Senior
                            Management, determined the 2022 annual performance assessment result and annual
                            remuneration of senior management based on the completion of business objectives of the
                            Company and work objectives of the senior management in 2022. On 16 January 2023, the
                            Board of the Company convened the 22th meeting of the 8th session of the Board, at which the
                            Resolution on Remuneration Distribution of Senior Management for the year 2022 was
                            considered and approved.
                            Except for fulfilling the job responsibilities of being directors, supervisors and senior
                            management of the Company, other remuneration paid for positions held in subsidiaries shall
                            be implemented according to the relevant remuneration system of the corresponding
                            subsidiaries.
                            Pursuant to the regulations such as the Management Policy on the Remuneration and
   Basis for determining    Performance Assessment of Senior Management, the result of performance assessment of
   remuneration of          senior management is determined based on the completion of business objectives of the
   directors, supervisors   Company and work objectives of the senior management in 2022. Based on the result of
   and senior               performance assessment, the performance bonus and remuneration of senior management in
   management               2022 were determined and submitted to be reviewed by the Remuneration Committee under
                            the Board who shall then submit it to the Board for review and resolution.
   Remuneration
   actually paid to
                            As at the date of the Report, remuneration of directors, supervisors and senior management has
   directors, supervisors
                            been fully paid.
   and senior
   management
   Total remuneration
   paid to all directors,
   supervisors and senior
                            RMB20.1058 million.
   management as of the
   end of the Reporting
   Period


  (IV) Changes in directors, supervisors and senior management
  √Applicable □N/A

       Name          Position     Change                                   Reason for change
    Xie Youguo      Supervisor    Resigned                                     Resigned
    Xing Zhiwei     Supervisor     Elected      Nominated by the Supervisory Committee and elected at the general meeting


  (V) Statement on punishments imposed by securities regulatory authorities in the last three years
  □Applicable √N/A

    (VI) Others
  □Applicable √N/A

  V. Board meetings held during the Reporting Period
   Meeting          Date of
                                                                     Meeting resolution
   session          meeting
                                  Eighteen (18) resolutions were considered and approved, including the Resolution on
                                  Changing Certain Projects Invested with Proceeds, the Resolution on the Opening a New
8th meeting of                    Special Account Designated for Proceeds and Proposed Signing the Proceeds Escrow
the 8th session    2022-01-24     Agreement by the Company and the Resolution on the 2021 Annual Performance
of the Board                      Assessment Result and Remuneration Distribution of Senior Management of the Company.
                                  See the Announcement on Resolutions of Joincare Pharmaceutical Group Industry Co., Ltd.
                                  at the 8th meeting of the 8th session of the Board (Lin 2022-006) for details
                                  Nineteen (19) resolutions were considered and approved, including the 2021 Annual Work
                                  Report of the President, 2021 Annual Work Report of the Board of Directors, 2021 Final
9th meeting of
                                  Account Report, 2021 Annual Profit Distribution Plan and 2021 Annual Report of Joincare
the 8th session    2022-03-29
                                  Pharmaceutical Group Industry Co., Ltd. (Full Text and Abstract). See the Announcement
of the Board
                                  on Resolutions of Joincare Pharmaceutical Group Industry Co., Ltd. at the 9th Meeting the
                                  8th Session of the Board of (Lin 2022-026) disclosed on 31 March 2022 for details



                                                            87
 Joincare Pharmaceutical Group                                                                     Annual Report 2022


                                 The 2022 Q1 Report of Joincare Pharmaceutical Group Industry Co., Ltd., the Resolution
                                 on the Second Phase Ownership Scheme under Medium to Long-term Business Partner
                                 Share Ownership Scheme of the Company (Draft) and its Summary, the Resolution on the
10th meeting of                  General Meeting for Granting Mandate to the Board to Deal with Matters Related to the
the 8th session   2022-04-22     Second Phase Ownership Scheme under Medium to Long-term Business Partner Share
of the Board                     Ownership Scheme of the Company and the Resolution on Convening the 2021 Annual
                                 General Meeting of the Company were considered and approved. See the Announcement on
                                 Resolutions of Joincare Pharmaceutical Group Industry Co., Ltd. at the 10th Meeting of the
                                 8th Session of the Board (Lin 2022-047) disclosed on 25 April 2022 for details
                                 The Resolution on the Amendment to the Second Phase Ownership Scheme under Medium
                                 to Long-term Business Partner Share Ownership Scheme of the Company (Draft) and its
11th meeting of
                                 Summary was considered and approved. See the Announcement of Joincare Pharmaceutical
the 8th session   2022-05-31
                                 Group Industry Co., Ltd. on the Amendment to the Second Phase Ownership Scheme under
of the Board
                                 Medium to Long-term Business Partner Share Ownership Scheme of the Company (Draft)
                                 and its Summary (Lin 2022-053) disclosed on 1 June 2022 for details
                                 The Resolution on Planning to Issue Global Depository Receipts Overseas and Listing on
12th meeting of                  the SIX Stock Exchange was considered and approved. See the Indicative Announcement of
the 8th session   2022-06-15     Joincare Pharmaceutical Group Industry Co., Ltd. on Planning to Issue Global Depository
of the Board                     Receipts Overseas and List on the SIX Stock Exchange (Lin 2022-061) disclosed on 16 June
                                 2022 for details
                                 Twenty (12) resolutions were considered and approved, including the Resolution on the
                                 Company’s Issuance of GDRs and Listing on the SIX Stock Exchange and Conversion into
                                 a Joint Stock Limited Company Offering Shares Overseas, the Resolution on the Plan for
13th meeting of
                                 the Company’s Issuance of GDRs and Listing on the SIX Swiss Exchange and the
the 8th session   2022-06-22
                                 Resolution on Report on the Utilization of the Proceeds Previously Raised by the Company.
of the Board
                                 See the Announcement on Resolutions of Joincare Pharmaceutical Group Industry Co., Ltd.
                                 at the 13th Meeting of the 8th Session of the Board (Lin 2022-063) disclosed on 23 June
                                 2022 for details
                                 The Resolution on Adjusting the Exercise Price of the 2018 Share Options Incentive Scheme
14th meeting of                  of the Company was considered and approved. See the Announcement of Joincare
the 8th session   2022-06-30     Pharmaceutical Group Industry Co., Ltd. on Adjusting the Exercise Price of the 2018 Share
of the Board                     Options Incentive Scheme of the Company (Lin 2022-069) disclosed on 1 July 2022 for
                                 details
                                 Six (6) resolutions were considered and approved, including the 2022 Interim Report of
                                 Joincare Pharmaceutical Group Industry Co., Ltd. and its Summary, the Special Report of
15th meeting of                  Joincare Pharmaceutical Group Industry Co., Ltd. on Deposit and Actual Use of Proceeds
the 8th session   2022-08-10     for the half year of 2022 and the Resolution on the 2022 Share Options Incentive Scheme
of the Board                     (Draft) and its Summary. See the Announcement on Resolutions of Joincare Pharmaceutical
                                 Group Industry Co., Ltd. at the 15th Meeting of the 8th Session of the Board (Lin 2022-083)
                                 disclosed on 11 August 2022 for details
                                 The Resolution on Matters Related to the Adjustment of the 2022 Share Options Incentive
16th meeting of                  Scheme and the Resolution on the First Grant of Share Options to Incentive Participants
the 8th session   2022-09-05     were considered and approved. See the Announcement on Resolutions of Joincare
of the Board                     Pharmaceutical Group Industry Co., Ltd. at the 16th Meeting of the 8th Session of the Board
                                 (Lin 2022-100) disclosed on 6 September 2022 for details
                                 The Resolution on the Cancellation of Certain Share Options Granted but Not Yet Exercised
                                 under the 2018 Share Options Incentive Scheme, the Resolution on Repurchase of Shares
17th meeting of                  through Centralized Bidding Transactions and the Resolution on the General Meeting for
the 8th session   2022-10-14     Granting Mandate to the Board to Deal with Matters Regarding the Repurchase. See the
of the Board                     Announcement on Resolutions of Joincare Pharmaceutical Group Industry Co., Ltd. at the
                                 17th Meeting of the 8th Session of the Board (Lin 2022-119) disclosed on 17 October 2022
                                 for details
                                 The 2022 Q3 Report of Joincare Pharmaceutical Group Industry Co., Ltd.,
                                 the Resolution on Change in Registered Capital of the Company, the Resolution on the
18th meeting of                  Amendment to Certain Clauses of the Articles of Association and the Resolution on
the 8th session   2022-10-26     Convening the 2022 Fourth Extraordinary General Meeting of the Company were
of the Board                     considered and approved. See the Announcement on Resolutions of Joincare Pharmaceutical
                                 Group Industry Co., Ltd. at the 18th Meeting of the 8th Session of the Board (Lin 2022-124)
                                 disclosed on 17 October 2022 for details
                                 The Resolution on Co-investment with Controlling Subsidiary Livzon Group was considered
19th meeting of
                                 and approved. See the Announcement of Joincare Pharmaceutical Group Industry Co., Ltd.
the 8th session   2022-11-28
                                 on Co-investment with Controlling Subsidiary Livzon Group (Lin 2022-136) disclosed on
of the Board
                                 29 November 2022 for details
20th meeting of                  The Resolution on the Establishment of a Joint Venture with Controlling Subsidiary Livzon
the 8th session   2022-12-12     Group and the Resolution relating to the Adjustment to Projected Daily Connected
of the Board                     Transactions between Controlling Subsidiaries Jiaozuo Joincare and Jinguan Electric Power


                                                           88
 Joincare Pharmaceutical Group                                                                        Annual Report 2022


                                   were considered and approved. See the Announcement on Resolutions of Joincare
                                   Pharmaceutical Group Industry Co., Ltd. at the 20th Meeting of the 8th Session of the Board
                                   (Lin 2022-141) disclosed on 13 December 2022 for details
                                   The Resolution on the Temporary Replenishment of Working Capital with Idle Proceeds was
21th meeting of
                                   considered and approved. See the Announcement of Joincare Pharmaceutical Group
the 8th session    2022-12-29
                                   Industry Co., Ltd. on the Temporary Replenishment of Working Capital with Idle Proceeds
of the Board
                                   (Lin 2022-146) disclosed on 30 December 2022 for details


 VI. Performance of duties by directors
 (1) Attendance by directors of the Board meetings and general meetings

                                                                                                                  Attendance
                                                     Attendance of the Board meetings                             at general
                                                                                                                   meetings
              Whether                                           Number                             Whether the
              indepen                                               of      Number                   director     Number of
  Name                        Number of           Number of                              Numb
                dent                                           meetings         of                  has been      attendances
                             meetings the          meetings                              er of
              director                                          attended    meetings               absent from        at the
                            director should        attended                              Absen
                                                                through     attended                   two           general
                          attend for the year     in person                               ces
                                                               electronic   by proxy               consecutive     meetings
                                                                 means                              meetings
Zhu Baoguo        No               14                 14            8           0           0          No              4
    Liu
                  No               14                 14           8            0           0          No              3
 Guangxia
 Yu Xiong         No               14                 14           8            0           0          No              5
    Qiu
                  No               14                 14           8            0           0          No              5
 Qingfeng
 Lin Nanqi        No               14                 14           8            0           0          No              5
 Cui Liguo        Yes              14                 14           8            0           0          No              5
 Huo Jing         Yes              14                 14           8            0           0          No              5
 Qin Yezhi        Yes              14                 14           8            0           0          No              5
 Peng Juan        Yes              14                 14           8            0           0          No              4

 Statement on absence from two consecutive meetings
 □Applicable √N/A

   Board meetings held during the year                                                                                 14
   In which: On-site meetings                                                                                           6
   Meetings held through electronic means                                                                               8
   Meetings held both in the form of on-site meeting and through electronic means                                       0


 (2) Objections raised by directors to affairs of the Company
 □Applicable √N/A

 (3) Others
 □Applicable √N/A

 VII. Board committees
 √Applicable □N/A
 (1). Members of the Board committees
         Committee name                                                     Member
 Audit Committee                        Qin Yezhi, Huo Jing, Peng Juan
 Nomination Committee                   Cui Liguo, Qiu Qingfeng, Huo Jing
 Remuneration Committee                 Huo Jing, Qin Yezhi, Peng Juan
 Strategy Committee                     Zhu Baoguo, Yu Xiong, Qin Yezhi, Cui Liguo, Peng Juan
 Corporate Social Responsibility
                                        Zhu Baoguo, Lin Nanqi, Cui Liguo
 (CSR) Committee


                                                              89
Joincare Pharmaceutical Group                                                                       Annual Report 2022




(2). 7 meetings were held by the Audit Committee during the Reporting Period
                                                                                                              Important
                                                                                                               opinion
  Date of meeting                                           Content
                                                                                                                 and
                                                                                                              suggestion
                      Review of the 2021 Annual Financial Statements of Joincare harmaceutical Group
 21 January 2022                                                                                               Approved
                      Industry Co., Ltd. (Unaudited)
                      Review of the Draft Audit Opinions for the 2021 Annual Financial Statements of
 21 March 2022                                                                                                 Approved
                      Joincare Pharmaceutical Group Industry Co., Ltd.
                      Review of the Audit Report for the 2021 Annual Financial Statements of the
                                                                                                               Approved
                      Company (Final)
                      Review of the Audit Report for the 2021 Annual Internal Control of the Company
                                                                                                               Approved
                      (Final)
                      Review of the Summary Report on Audit Work for the Year 2021 from Grant Thornton
                                                                                                               Approved
                      (Special General Partnership)
                      Review of the Self-Assessment Report of Joincare Pharmaceutical Group Industry Co.,
 29 March 2022                                                                                                 Approved
                      Ltd. on Risk Management and Internal Control for the Year 2021
                      Review of the Resolution on Appointment of Grant Thornton (Special General
                                                                                                               Approved
                      Partnership) as the Auditor of the Company for the Year 2022
                      Review of the Resolution on Daily Connected Transactions between the Controlling
                                                                                                               Approved
                      Subsidiaries Jiaozuo Joincare and Jinguan Electric Power
                      Review of the Resolution on Providing Loan Guarantee for Jinguan Electric Power by
                                                                                                               Approved
                      the Company and its Controlling Subsidiary Jiaozuo Joincare
 22 April 2022        Review of the 2022 Q1 Report of Joincare Pharmaceutical Group Industry Co., Ltd.         Approved
 26 October 2022      Review of the 2022 Q3 Report of Joincare Pharmaceutical Group Industry Co., Ltd.         Approved
 28 November          Review of the 2022 Financial Statements and Internal Control Audit Proposal of
                                                                                                               Approved
 2022                 Joincare Pharmaceutical Group Industry Co., Ltd.
 12 December          the Resolution relating to the Adjustment to Projected Daily Connected Transactions
                                                                                                               Approved
 2022                 between Controlling Subsidiaries Jiaozuo Joincare and Jinguan Electric Power


(3). 4 meetings were held by the Remuneration Committee during the Reporting Period
                                                                                                              Important
   Date of
                                                        Content                                              opinion and
   meeting
                                                                                                              suggestion
 24 January      Review of the Resolution on the 2021 Annual Performance Assessment Result and
                                                                                                              Approved
 2022            Remuneration Distribution of Senior Management of the Company
                 Review of the Review of the Resolution on the 2022 Share Options Incentive Scheme
                                                                                                              Approved
 10 August       (Draft) and its Summary
 2022            Resolution on the Administrative Measures for Appraisal System of the 2022 Share
                                                                                                              Approved
                 Options Incentive Scheme of the Company
                 Review of the Resolution on Matters Related to the Adjustment of the 2022 Share Options
 5 September                                                                                                  Approved
                 Incentive Scheme
 2022
                 Review of the Resolution on the First Grant of Share Options to Incentive Participants       Approved
 14 October      Review of the Resolution relating to Cancellation of Certain Share Options of the
                                                                                                              Approved
 2022            Company Granted but Not Yet Exercised under the 2018 Share Options Incentive Scheme


(4). 4 meetings were held by the Strategy Committee during the Reporting Period
    Date of                                                                                           Important opinion
                                                      Content
    meeting                                                                                            and suggestion
                   Review of the Resolution on Planning to Issue Global Depository Receipts
 15 June 2022                                                                                              Approved
                   Overseas and Listing on the SIX Stock Exchange
                   Review of the Resolution on the Company’s Issuance of GDRs and Listing on the
                   SIX Stock Exchange and Conversion into a Joint Stock Limited Company Offering           Approved
                   Shares Overseas
 22 June 2022      Review of the Resolution on the Plan for the Company’s Issuance of GDRs and
                                                                                                           Approved
                   Listing on the SIX Swiss Exchange
                   Review of the Resolution on the Plan for the Use of Proceeds Raised by the
                                                                                                           Approved
                   Issuance of GDRs
 28 November       Review of the Resolution on Co-investment with Controlling Subsidiary Livzon
                                                                                                           Approved
 2022              Group



                                                          90
Joincare Pharmaceutical Group                                                                         Annual Report 2022


 12 December      Review of the Resolution on the Establishment of a Joint Venture with Controlling
                                                                                                             Approved
 2022             Subsidiary Livzon Group


(5). 2 meetings were held by the Corporate Responsibility Committee during the Reporting Period
                                                                                                        Important opinion
  Date of meeting                                       Content
                                                                                                         and suggestion
                     Review of the 2021 Corporate Social Responsibility Report of Joincare
                                                                                                             Approved
                     Pharmaceutical Group Industry Co., Ltd.
                     Review of the Resolution on the Set-up of Environmental Management
                                                                                                             Approved
  29 March 2022      Targets for Carbon Emissions of Joincare Group
                     Review of the Resolution on the Introduction of ESG Indicator Assessment
                     Mechanism into Individual Performance of the Corporate Responsibility Work              Approved
                     Group of Joincare Pharmaceutical Group
                     Review of the Resolution on the Establishment of 2022 Corporate
   23 November
                     Responsibility Work Group of Joincare Pharmaceutical Group Industry Co.,                Approved
       2022
                     Ltd.


(6). Affairs subject to objection
□Applicable √N/A

VIII. Statement on risks of the Company identified by the Board of Supervisors
□Applicable √N/A
The Supervisory Committee had no objection to the matters under their supervision within the reporting
period.

IX. Employees of the parent company and major subsidiaries
(I)    Employees
 Number of active employees of the parent company                                                                 517
 Number of active employees of major subsidiaries                                                              13,599
 Total number of employees                                                                                     14,116
 Number of retired employees for whom the parent company and major
                                                                                                                  669
 subsidiaries need to pay certain expenses
                                                   Profession
                                  Category                                                  Number
 Production staff                                                                                               8,312
 Sales staff                                                                                                    2,635
 Technical staff                                                                                                2,181
 Financial staff                                                                                                  258
 Administrative staff                                                                                             730
                                    Total                                                                      14,116
                                              Education background
                           Education background                                             Number
 PhD                                                                                                               64
 Postgraduate                                                                                                     620
 Undergraduate                                                                                                  3,730
 Junior college diploma                                                                                         4,021
 Others                                                                                                         5,681
                                    Total                                                                      14,116


(II) Compensation policy
√Applicable □N/A
The Company implements scientific, reasonable and incentive-based compensation strategies. Based on
scientific analysis and assessment of the organizational structure and job responsibilities, the Company
determines the relative value of each position, and by combining the external market compensation data
and the ability of the Company to pay, the Company provides a reasonable employee compensation
package. Employee compensation consists of two parts: fixed income and variable income. Variable
income is linked to business results of the Company and individual performance of employees. In this


                                                          91
Joincare Pharmaceutical Group                                                               Annual Report 2022


way, employees are encouraged to increase their enthusiasm and motivation at work. Competitive
compensation policies are adopted for talents in key positions and those urgently needed in the market, so
as to prevent loss of key talents and provide a talent pool for the development of the Company.

  (III) Training programs
√Applicable □N/A
In 2022, the Company continued to attach great importance to internal talent training. With multi-level,
diversified training systems and a combination of online and offline learning, the Company organized and
carried out new employee orientation training, employee on-the-job training, career-based study for a
master's or doctor's degree, training and team building. Meanwhile, the Company encouraged employees
to actively participate in external learning activities related to work, facilitated the improvement of
employee competence and team cohesion, and built talent teams.

 (IV) Outsourced workers

□Applicable √N/A

X. Profit distribution proposal or proposal for capitalization of capital reserve
(I) Formulation, implementation or adjustment of cash dividend distribution policy
√Applicable □N/A
1. Cash dividend distribution policy and its formulation
To establish a scientific, consistent and stable decision-making and supervision mechanism for dividends,
and fully protect and safeguard the rights and interests of the majority of shareholders, the Company
formulated this cash dividend policy in accordance with the Regulatory Guidelines for Listed Companies
No. 3 - Distribution of Cash Dividends of Listed Companies released by the CSRC (CSRC announcement
[2022] No. 3) and the Regulatory Guideline for Self-regulation of Listed Companies No. 1 - Standardized
Operation released by Shanghai Stock Exchange and other relevant documents and requirements, and in
light of the reality of the Company, clarified the formulation, decision-making and adjustment procedures
for the policy in the Articles of Association: If the Company is in a sound operating condition and its cash
flow can meet the needs of normal operation and long-term development, the Company shall actively
implement the profit distribution policy to provide reasonable returns to investors while taking into
account the sustainable development of the Company, in order to maintain the continuity and stability of
the policy. The profits may be distributed in cash, stocks, or combination thereof or in any other way
permitted by laws and regulations. Cash dividends are superior to stock dividends in the distribution of
profits, and shall be adopted whenever the conditions are met. Unless otherwise provided for in the Articles
of Association, the profits distributed in cash shall not be less than 10% of the distributable profits realized
in the current year. The specific amount and proportion of cash dividends for each year shall be determined
by the Board of Directors of the Company in accordance with relevant provisions and in light of the
Company's current operating situation, and shall be reported to the annual general meeting for deliberation
and decision.
2. Implementation of cash dividend distribution policy in 2022
On 18 May 2022, the Company convened the 2021 Annual General Meeting, at which the Company's
Profit Distribution Plan for 2021 was considered and approved: a cash dividend of RMB1.50 (tax inclusive)
will be distributed to all shareholders for every 10 shares, based on the total share capital of the Company
on the equity registration date as determined for implementation of the Company's profit distribution plan
for 2021, minus the total number of shares in the Company's special securities account for repurchase,
with the remaining undistributed profits to be carried forward to the following year. As of the end of this
Reporting Period, the above cash dividends have been fully distributed.

                                                      92
Joincare Pharmaceutical Group                                                                           Annual Report 2022


3. Profit distribution scheme for 2022
Based on the audit conducted by Grant Thornton (Special General Partnership), in 2022, the Parent
Company generated net profit of RMB849,731,957.95, 10% of which was contributed to the statutory
surplus reserve, namely RMB84,973,195.80, the remainder of which, together with undistributed profits
for the last year of RMB1,400,174,178.18 and gain on disposal of other equity investments of
RMB80,749,859.60, subtracting cash dividends for the last year of RMB277,557,631.65, is the profits
available for distribution to shareholders for the year of RMB1,968,125,168.28.The Company plans to
distribute cash dividends for the fiscal year 2022, based on the total number of shares for dividend
distribution, which is defined by the total shares of Company, minus the shares in the Share Repurchase
Account, on the equity registration date designated by the annual profit distribution plan. The Company
plans to distribute cash dividend of RMB1.80 (tax inclusive) for every 10 shares of to all shareholders of
the Company, and the remaining undistributed profits will be carried forward to the following year.
4. Modification and adjustment of the cash dividend distribution policy during the Reporting Period
The Company's cash dividend policy was not modified or adjusted during the Reporting Period.

(II) Special statement on cash dividend distribution policy
√Applicable □N/A
 Whether it meets the requirements of the articles of association or the resolution of the general meeting    √Yes □No
 Are there defined and clear distribution qualifications and proportions                                      √Yes □No
 Are there well-designed decision-making procedures and system                                                √Yes □No
 Have independent directors performed their duties and role properly                                          √Yes □No
 Whether the minority shareholders have the chance to fully express their opinions and demands and
                                                                                                              √Yes □No
 whether their legitimate rights and interests have been well protected


(III) If the Company made a profit during the Reporting Period and there's profit distributable by
the parent company to shareholders, but the Company does not propose to distribute profits in cash,
the Company shall explain the reason in detail, usage of the undistributed profit and usage plan

□Applicable √N/A
  (IV) Profit distribution and conversion of capital reserve into share capital for the Reporting
Period
√Applicable □N/A

                                                                                              Unit: Yuan Currency: RMB
 Number of bonus shares to be distributed for every ten shares (share)                                          0
 Amount to be distributed for every ten shares (RMB) (tax inclusive)                                         1.80
 Number of shares to be converted into share capital for every ten shares (share)                               0
 Amount of cash dividend (tax inclusive)                                                          342,139,018.68
 Net profit attributable to ordinary shareholders of the listed company in the consolidated
                                                                                                1,502,595,840.48
 financial statement during the year of distribution
 Percentage of the net profit attributable to ordinary shareholders of the listed company
                                                                                                           22.77
 in the consolidated financial statement (%)
 Amount of repurchase of shares under cash offer included in cash dividend                        724,513,822.62
 Total amount of dividend (tax inclusive)                                                       1,066,652,841.30
 Total amount of dividend as a percentage of the net profit attributable to ordinary
                                                                                                           70.99
 shareholders of the listed company in the consolidated financial statement (%)
     Note: The Company proposes to distribute cash dividend of RMB1.80 (tax inclusive) for every 10 shares to all
shareholders of the Company (except for those in the Share Repurchase Account of the Company). The cash dividends
proposed to be distributed for 2022 will be RMB342,139,018.68 (tax inclusive) based on the total share capital of
1,929,189,374 shares less the 28,417,048 shares in the Share Repurchase Account of the Company as of 31 December 2022.
The final and actual total distribution amount is calculated based on the total shares entitled to participate in the equity
distribution on the equity registration date for the implementation of equity distribution.

                                                              93
 Joincare Pharmaceutical Group                                                                          Annual Report 2022




 XI Share incentive plan, employee share ownership scheme and other employee incentives of the
 Company and their effect
 (1) Matters related to equity incentive scheme have been disclosed have been disclosed in the
 provisional announcements without progress or change in subsequent implementation
 √Applicable □N/A

                            Overview                                                       Query index
The number of share options exercised was 4,005,170 from 1
                                                                      See the Announcement on 2022 Q1 Independent Exercise
January 2022 to 31 March 2022. As of 31 March 2022, the
                                                                      Results of the 2018 Share Options Incentive Scheme of
number of options cumulatively exercised and completing share
                                                                      Joincare Pharmaceutical Group Industry Co., Ltd. &
transfer registration during the exercise period of the first grant
                                                                      Changes in Shares (Lin 2022-038) disclosed by the
and reserved grant under the 2018 Share Options Incentive
                                                                      Company on 2 April 2022 for details.
Scheme of the Company was 28,835,036.
The Resolution on the Second Phase Share Ownership Scheme
under Medium to Long-term Business Partner Share Ownership
                                                                      See the relevant Announcements on the Second Phase
Scheme of the Company (Draft) and its Summary and the
                                                                      Share Ownership Scheme under Medium to Long-term
Resolution on the General Meeting for Granting Mandate to the
                                                                      Business Partner Share Ownership Scheme of Joincare
Board to Deal with Matters Related to the Second Phase Share
                                                                      Pharmaceutical Group Industry Co., Ltd. (Draft) and its
Ownership Scheme under Medium to Long-term Business
                                                                      Summary disclosed by the Company on 25 April 2022 for
Partner Share Ownership Scheme of the Company were
                                                                      details;
considered and approved at the Congress of Workers and Staff,
                                                                      See the Announcement on Resolutions of Joincare
the 10th Meeting of the 8th Session of the Board, and the 9th
                                                                      Pharmaceutical Group Industry Co., Ltd. at the 2021
Meeting of the 8th Session of the Supervisory Committee on 22
                                                                      Annual General Meeting (Lin 2022-051) disclosed by the
April 2022.
                                                                      Company on 19 May 2022 for details.
The said resolutions were considered and approved at the 2021
Annual General Meeting on 18 May 2022.
                                                                      See the Announcement on Resolution in Relation to
                                                                      Revision of the Second Phase Share Ownership Scheme
The Resolution on Revision of the Second Phase Share
                                                                      under Medium to Long-term Business Partner Share
Ownership Scheme under Medium to Long-term Business
                                                                      Ownership Scheme of Joincare Pharmaceutical Group
Partner Share Ownership Scheme of Joincare Pharmaceutical
                                                                      Industry Co., Ltd. (Draft) and its Summary (Lin 2022-
Group Industry Co., Ltd. (Draft) and its Summary was
                                                                      053), and the Second Phase Share Ownership Scheme
considered and approved at the 11th Meeting of the 8th Session
                                                                      under Medium to Long-term Business Partner Share
of the Board and at the 10th Meeting of the 8th Session of the
                                                                      Ownership Scheme of Joincare Pharmaceutical Group
Supervisory Committee on 31 May 2022.
                                                                      Industry Co., Ltd. (Revised Draft) and its Summary
                                                                      disclosed by the Company on 1 June 2022 for details.
On 1 June 2022, the First Holders’ Meeting of the Second Phase
Share Ownership Scheme of Medium to Long-term Business
Partners was held by the Company, at which the Resolution on
                                                                      See the Announcement on Resolutions of Joincare
Establishing the Management Committee of the Second Phase
                                                                      Pharmaceutical Group Industry Co., Ltd. at the First
Share Ownership Scheme of the Company, the Resolution on
                                                                      Holders’
Electing Members of the Management Committee of the Second
                                                                      Meeting of the Second Phase Share Ownership Scheme of
Phase Share Ownership Scheme and the Resolution on
                                                                      Medium to Long-term Business Partners (Lin 2022-056)
Authorizing the Management Committee of the Second Phase
                                                                      disclosed by the Company on 2 June 2022 for details.
Share Ownership Scheme of the Company to Handle Matters
Related to the Employee Share Ownership Scheme were
considered and approved.
As of 7 June 2022, the Second Phase Share Ownership Scheme
of the Company has purchased a total of 6,275,372 shares by           See the Announcement of Joincare Pharmaceutical Group
way of secondary market centralized bidding trading,                  Industry Co., Ltd. on Completing the Purchase of Shares
representing 0.33% of the total share capital of the Company at       for the Second Phase Share Ownership Scheme under
that time, with a total turnover of RMB75,740,661.60 and an           Medium to Long-term Business Partner Share Ownership
average transaction price of approximately RMB12.07 per share.        Scheme (Lin 2022-059) disclosed by the Company on 8
Then the Company has completed the purchase of the underlying         June 2022 for details.
shares for the Second Phase Share Ownership Scheme.
The Resolution on Adjusting the Exercise Price of the 2018
Share Options Incentive Scheme of the Company was
                                                                      See the Announcement on Adjusting the Exercise Price of
considered and approved at the 14th Meeting of the 8th Session
                                                                      the 2018 Share Options Incentive Scheme of the Company
of the Board and at the 12th Meeting of the 8th Session of the
                                                                      by Joincare Pharmaceutical Group Industry Co., Ltd. (Lin
Supervisory Committee on 30 June 2022. Due to profit
                                                                      2022-069) disclosed by the Company on 1 July 2022 for
distribution, the exercise price under the first grant was adjusted
                                                                      details.
to RMB7.59 per share, while that under the reserved grant was
adjusted to RMB10.01 per share.


                                                                94
 Joincare Pharmaceutical Group                                                                        Annual Report 2022


The number of options exercised in total was 807,589 from 1         See the Announcement on 2022 Q2 Independent Exercise
April 2022 to 30 June 2022. As at 30 June 2022, the number of       Results of the 2018 Share Options Incentive Scheme of
options cumulatively exercised and completing share transfer        Joincare Pharmaceutical Group Industry Co., Ltd. &
registration under the first grant and reserved grant of the 2018   Changes
Share Options Incentive Scheme of the Company was                   in Shares (Lin 2022-071) disclosed by the Company on 2
29,642,625.                                                         July 2022 for details.
                                                                    See the Announcement on the 2022 Share Options
The Resolution on the 2022 Share Options Incentive Scheme           Incentive Scheme (Draft) and its Summary of Joincare
(Draft) and its Summary of the Company and other relevant           Pharmaceutical Group Industry Co., Ltd. (Lin 2022-087)
resolutions were considered and approved at the 15th Meeting        and relevant announcements disclosed by the Company on
of the 8th Session of the Board and at the 13th Meeting of the      11 August 2022 for details;
8th Session of the Supervisory Committee on 10 August 2022.         See the Announcement on Resolutions of Joincare
The above resolutions were considered and approved at the 2022      Pharmaceutical Group Industry Co., Ltd. at the 2022 third
third extraordinary general meeting on 29 August 2022.              extraordinary general meeting (Lin 2022-095) disclosed
                                                                    by the Company on 30 August 2022 for details.
The Resolution on the Matters Related to the Adjustment of the
2022 Share Options Incentive Scheme and the Resolution on the
                                                                    See the Announcement on the Matters Related to the
First Grant of Share Options to Incentive Participants were
                                                                    Adjustment of the 2022 Share Options Incentive Scheme
considered and approved at the 16th Meeting of the 8th Session
                                                                    of Joincare Pharmaceutical Group Industry Co., Ltd. (Lin
of the Board and at the 14th Meeting of the 8th Session of the
                                                                    2022-101), the Announcement on the First Grant of Share
Supervisory Committee on 5 September 2022. The number of
                                                                    Options to Incentive Participants of Joincare
incentive participants under this incentive scheme was adjusted
                                                                    Pharmaceutical Group Industry Co., Ltd. (Lin 2022-102)
from 430 to 423, while the number of share options granted was
                                                                    and other relevant announcements disclosed by the
adjusted from 55,000,000 to 54,950,000. The first grant date was
                                                                    Company on 6 September 2022 for details.
5 September 2022, and 49,450,000 share options were granted
to 423 incentive participants.
The number of options exercised was 2,249,270 from 1 July
                                                                    See the Announcement on 2022 Q3 Independent Exercise
2022 to 30 September 2022. As at 30 September 2022, the
                                                                    Results of the 2018 Share Options Incentive Scheme of
number of options cumulatively exercised and completing share
                                                                    Joincare Pharmaceutical Group Industry Co., Ltd. &
transfer registration under the first grant and reserved grant of
                                                                    Changes in Shares (Lin 2022-115) disclosed by the
the 2018 Share Options Incentive Scheme of the Company was
                                                                    Company on 11 October 2022 for details.
31,891,895.
The Resolution relating to the Cancellation of Certain Share
Options of the Company Granted but Not Yet Exercised under
the 2018 Share Option Incentive Plan was considered and
approved at the 17th meeting of the 8th session of the Board and
the 15th meeting of the 8th session of the Supervisory              See the Announcement on the Cancellation of Certain
Committee of the Company on 14 October 2022, 26,000 share           Share Options of the Company Granted but Not Yet
options under the reserved grant that have been granted but not     Exercised under the 2018 Share Option Incentive Plan of
yet exercised by certain incentive participants were cancelled      Joincare Pharmaceutical Group Industry Co., Ltd. (Lin
due to not being exercised by them within the validity period of    2022-120) disclosed by the Company on 17 October 2022
the options.                                                        for details.
Upon review and confirmation by the Shanghai Branch of China
Securities Depository and Clearing Corporation Limited, the
said cancellation of 26,000 share options was completed on 24
October 2022.
The number of options exercised was 1,534,105 from 1 October
                                                                    See the Announcement on 2022 Q4 Independent Exercise
2022 to 31 December 2022. As at 31 December 2022, the
                                                                    Results of the 2018 Share Options Incentive Scheme of
number of options cumulatively exercised and completing share
                                                                    Joincare Pharmaceutical Group Industry Co., Ltd. &
transfer registration under the first grant and reserved grant of
                                                                    Changes in Shares (Lin 2023-001) disclosed by the
the 2018 Share Options Incentive Scheme of the Company was
                                                                    Company on 4 January 2023 for details
33,426,000.

 (2) Incentives not disclosed in the provisional announcements or with subsequent progress

 Equity incentives
 □Applicable √N/A

 Others
 □Applicable √N/A

 Employee share ownership scheme
 □Applicable √N/A


                                                              95
 Joincare Pharmaceutical Group                                                                      Annual Report 2022


 Other incentive program
 □Applicable √N/A

 (3) Equity incentives granted to directors and senior management during the Reporting Period
 √Applicable □N/A

                                                                                                    Unit: 10,000 shares
                                 Number     Number of                   Number
                                                                                                      Number      Market
                                 of share     newly      Number of         of
                                                                                                      of share    price at
                                 options     granted     exercisable   exercised
                                                                                   Exercise price     options    the end of
                                  held at     share        options      options
  Name            Title                                                               of share        held at        the
                                    the      options     during the     during
                                                                                   options(RMB)       the end    Reporting
                                beginning   during the   Reporting        the
                                                                                                       of the      Period
                                  of the    Reporting      Period      Reporting
                                                                                                       period      (RMB)
                                   year       Period                     Period
            Director,
Yu Xiong                           14          80              14         14           7.74             80         11.29
            President
            Director, Vice
Lin Nanqi                          24          80              24         24           7.74             80         11.29
            President
            Director, Vice
Qiu
            President, Chief       18          60              18         18           7.74             60         11.29
Qingfeng
            Financial Officer
Zhao        Vice President,
                                   18          60              18         18           7.59             60         11.29
Fengguang   Board Secretary
   Total            /              74          280             74         74             /              280          /


 (4) Performance assessment mechanism for senior management during the Reporting Period, and
 the development and implementation of incentive scheme
 √Applicable □N/A

 According to the relevant provisions of the Company such as the Remuneration and Performance
 Appraisal Management System for Senior Management, the plans on performance appraisal results and
 remuneration of senior management for the year 2022 are set based on the completion of the operation
 targets of the Company and the corresponding personal performance of each senior management for the
 year 2022. The plans shall be submitted to the Board for review and approval. During the Reporting Period,
 senior management of the Company faithfully performed their duties in strict accordance with the
 Company Law, the Articles of Association and other relevant regulations, actively implemented the
 relevant resolutions of the Company's General meetings and the Board meetings, actively adjusted
 business plans under the guidance of the Board, continuously strengthened internal control management,
 and strived to improve the Company's core competitiveness.

 XII. Development and implementation of internal controls during the Reporting Period
 √Applicable □N/A

 During the Reporting Period, the Company carried out standard operation and risk control in strict
 accordance with the laws and regulations in China and the internal control system of the Company. The
 Company established a rigorous internal control management system, continued to optimize and improve
 the internal control system by combining the industry characteristics and the actual operation of the
 Company, enhanced its decision-making efficiency, and ensured the legal compliance of business
 management and the security of corporate assets, facilitating the steady implementation of strategies of
 the Company. Thanks to an effective internal control mechanism, the Company can prevent, timely
 identify and correct any deviation in the operation and management, and can reasonably ensure the security
 and integrity of corporate assets, as well as the authenticity, accuracy and completeness of accounting
 information, safeguarding the interests of the Company and all shareholders.




                                                          96
Joincare Pharmaceutical Group                                                           Annual Report 2022


Based on the identification of material deficiencies of internal control of the Company, there was no
material deficiency or significant deficiency of internal control over financial reporting and non-financial
reporting in the Company for the year 2022. Through operation, analysis and evaluation of the internal
control system, the Company effectively prevented business management risks, and promoted the
achievement of internal control objectives. Looking ahead, the Company will continue to improve the
internal control system, standardize its implementation, strengthen the supervision and inspection over
internal control, and promote the healthy and sustainable development of the Company. See the Risk
Management and Internal Control Self-Assessment Report 2022 of Joincare Pharmaceutical Industry
Group Co., Ltd. disclosed by the Company on 11 April 2023 for details.
Statement on material loopholes in internal controls during the Reporting Period
□Applicable √N/A

XIII. Management and control of subsidiaries during the Reporting Period
√Applicable □N/A
The Company formulated relevant subsidiary management rules, such as the Detailed Rules for
Standardized Operation and Management of Subsidiaries, to strengthen internal control of wholly-owned
and majority-owned subsidiaries by specifying their governance structure, the management of the Board,
the general meetings and the Supervisory Committee, special transactions, legal person's authorization
and relevant issues, to improve the Company's overall operating efficiency and risk control capability.
During the Reporting Period, the Company exercised management and control over its subsidiaries in
accordance with the Company Law, the Articles of Association and other relevant laws and regulations.
First, it provided guidance for the subsidiaries as to how to improve the corporate governance structure,
and how to revise and improve the Articles of Association and other relevant systems in accordance with
relevant laws and regulations; second, through internal training such as training on connected transactions,
the Company urged subsidiaries to report to the Company on connected transactions, external guarantee
and other major matters in advance; third, the Company updated the internal control manual and related
materials, to improve the internal control system, and strengthen implementation and enhance the
effectiveness of internal control.

XIV. Related information on internal control audit report
√Applicable □N/A
In accordance with relevant standards, guidelines and regulatory documents, and upon the approval by the
audit committee of the Board of Directors, the Board of Directors and the general meeting, the Company
engaged Grant Thornton China (special general partnership) to conduct internal control audit in 2022. In
accordance with the Basic Standards for Enterprise Internal Control and the Application Guidelines for
Enterprise Internal Control, Grant Thornton China conducted audit of the effectiveness of internal control
over financial reporting of the Company and its subsidiaries as of 31 December 2022, and issued a standard
internal control audit report with unqualified opinion. See the Internal Control Audit Report 2022 of
Joincare Pharmaceutical Industry Group Co., Ltd. disclosed by the Company on 11 April 2023 for details.

Disclosure of internal control auditor's report: Yes
Types of internal control auditor's opinion: Standard unqualified opinion

XV. Rectification of self-examined deviations in the Special Action for Governance of Listed
Companies
1. Optimization of the meeting convening methods of the Board of Directors and Special Committees
of the Board
Description: At present, the Board of Directors and the special committees mostly hold meetings through
electric means which is not conducive to full expression of opinions by directors.

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Joincare Pharmaceutical Group                                                             Annual Report 2022


Rectification measures: In order to ensure that directors can fully express their opinions, the Company
will increase the number of on-site meetings of the Board of Directors and its special committees. In
particular, on-site meetings or on-site + virtual means will be held for matters related to major asset
purchase or sale or major connected transactions in the future. In 2022, the Company held 6 meeting
through a combination of on-site + virtual means, accounted for 42.86% of the number of all meetings,
representing an increase of 38.51% over 2021
2. Improvement of the audit institution selection and engagement review process
Description: The special self-inspection found that the Company engaged the audit institution based on
inquiry into public available information on its professional competence and integrity, without consulting
the record of integrity of the audit institution in the securities and futures market through the China
Securities Regulatory Commission in advance.
Rectification measures: From 2021, in addition to the inquiry into public available information, the
Company would, before selecting and engaging an audit institution, consult the records of integrity of the
audit institution and relevant certified public accountants to be engaged in the securities and futures market
as maintained by Shenzhen Securities Regulatory Bureau, to fully learn about its practicing experience,
professional competence and integrity


XVI. Others
□Applicable √N/A




                                                     98
                 Joincare Pharmaceutical Group                                                                                Annual Report 2022




                                             Chapter 5 Environmental and Social Responsibility
                 I. Environmental information
                   If the environment protection mechanism was
                                                                                                                                                 Yes
                   established
                   Amount of funds invested in environment protection
                                                                                                                                            12,273.48
                   during the Reporting Period (Unit: RMB0’000)


                 (I) Environmental issues of companies and their major subsidiaries belonging to key
                 pollutant discharging units as announced by the environmental protection department
                 √ Applicable □ N/A
                 1. Pollution discharge information
                 √ Applicable □ N/A
                 ⅰJiaozuo Joincare
                                                                                                               Pollutant                         Total
                                                         Number                                                                 Total
  Name of         Name of major                                         Number of           Discharge          discharge                       amount of
                                         Mode of            of                                                                amount of                     Excessive
company or         pollutants and                                       discharge          concentratio        standards                       discharge
                                         discharge      discharge                                                             discharge                     discharge
 subsidiary      specific pollutants                                     outlets            n (mg/L)         implemented                       approved
                                                         outlets                                                                 (t/a)
                                                                                                                (mg/L)                            (t/a)
                 Chemical oxygen                                     Master outlet in
                                        Continuous                                             119              220             757              942.1         Nil
  Jiaozuo           demand                                              sewage
                                                            1
  Joincare           Ammonia                                           treatment
                                        Continuous                                             14                35              91              105.3         Nil
                     nitrogen                                          workshop


                 ⅱTaitai Pharmaceutical
                                                                                                                Pollutant                         Total
                    Name of major                         Number                                                                 Total
   Name of                                                               Number of           Discharge          discharge                       amount of
                    pollutants and        Mode of            of                                                                amount of                     Excessive
 company or                                                              discharge          concentratio        standards                       discharge
                       specific           discharge      discharge                                                             discharge                     discharge
  subsidiary                                                              outlets            n (mg/L)         implemented                       approved
                      pollutants                          outlets                                                                 (t/a)
                                                                                                                 (mg/L)                            (t/a)
                       Chemical
                                                                                               39.44             345             0.35             19.34         Nil
                    oxygen demand
                      Biochemical                                     Master outlet in
                                                                         sewage                 3.05             150             0.021              /           Nil
                    oxygen demand        Intermittent          1
                                                                        treatment
                       Suspended
    Taitai                                                              workshop                 4               250             0.034              /           Nil
                         solids
Pharmaceutical
                        pH value                                                                7.66             6~9              /                /           Nil
                     Sulfur dioxide                                                             1.69              50             0.20               /           Nil
                                                                         Discharge
                    Nitrogen oxide                                                             13.92              150            0.16               /           Nil
                                         Intermittent          1       outlet of boiler
                       Particulate
                                                                        exhaust gas            14.26              20             0.15               /           Nil
                         matter


                 iii Haibin Pharma
                                                                                                                  Pollutant                       Total
                  Name of major                          Number                                                                   Total
  Name of                                                                                      Discharge          discharge                     amount of
                  pollutants and        Mode of             of       Number of discharge                                        amount of                    Excessive
company or                                                                                    concentratio        standards                     discharge
                     specific           discharge       discharge         outlets                                               discharge                    discharge
 subsidiary                                                                                    n (mg/L)         implemented                     approved
                    pollutants                           outlets                                                                   (t/a)
                                                                                                                   (mg/L)                          (t/a)
                     Chemical
                                                                                                     54.8             500             3.2         41.65         Nil
                  oxygen demand                                        Master outlet in
                     Ammonia                               1          sewage treatment
                                                                                                     0.99              45          0.06            3.75         Nil
                     nitrogen                                            workshop
                   Total nitrogen                                                                    6.09              70         0.3374           5.83         Nil
  Haibin
                   Total volatile      Intermittent
  Pharma                                                             Discharge outlet of
                      organic                              1                                         0.42             100         0.0013           0.50         Nil
                                                                     process exhaust gas
                    compounds
                                                                     Discharge outlet of
                   Non-methane
                                                           1           exhaust gas in               11.27              60          0.87            5.04         Nil
                   hydrocarbon
                                                                       sewage station




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                Joincare Pharmaceutical Group                                                                                 Annual Report 2022


                iv Xinxiang Haibin
                   Name of                                                                                        Pollutant                     Total
                                                        Number                                                                   Total
  Name of            major                                                                      Discharge         discharge                   amount of
                                      Mode of              of             Number of                                            amount of                   Excessive
company or       pollutants and                                                               concentration       standards                   discharge
                                      discharge        discharge       discharge outlets                                       discharge                   discharge
 subsidiary         specific                                                                     (mg/L)         implemented                   approved
                                                        outlets                                                                   (t/a)
                   pollutants                                                                                      (mg/L)                        (t/a)
                   Chemical
                    oxygen                                              Master outlet in         66.01              220            9.8          14.81          Nil
 Xinxiang
                    demand           Continuous           1            sewage treatment
  Haibin
                   Ammonia                                                workshop
                                                                                                  5.22               35           0.78           1.66          Nil
                    nitrogen


                v Fuzhou Fuxing
                 Name of                                                                                          Pollutant                      Total
                                                      Number
  Name of           major                                                                        Discharge        discharge       Total        amount of
                                   Mode of               of           Number of discharge                                                                  Excessive
company or       pollutants                                                                    concentration      standards    amount of       discharge
                                   discharge         discharge             outlets                                                                         discharge
 subsidiary     and specific                                                                      (mg/L)         implemente   discharge (t)    approved
                                                      outlets
                 pollutants                                                                                       d (mg/L)                        (t/a)
                 Chemical
                   oxygen
                  demand                                                                           16.59            100          19.41           102.19       Nil
  Fuzhou                                                              The northwest side
                                  Intermittent           1
  Fuxing         (COD)                                                of the factory
                 Ammonia
                                                                                                   0.22              15          0.255           10.22        Nil
                  nitrogen
                Note: The discharge concentration represents the actual discharge concentration. The standards implemented
                represent the standards for discharge to the environment by Jiangyin sewage plant (江阴污水处理厂) (i.e. COD
                ≤100mg/L, ammonia nitrogen ≤15mg/L), and the agreed standard for discharge of COD and ammonia nitrogen
                from the company to Jiangyin sewage plant shall be ≤500mg/L and ≤60mg/L, respectively. The data was obtained
                from Fuqing Environmental Protection Bureau.

                vi Livzon Xinbeijiang
                  Name of                                                                                         Pollutant                     Total
                                                      Number                                                                    Total
  Name of           major                                                                        Discharge        discharge                   amount of
                                     Mode of             of        Number of discharge                                        amount of                    Excessive
company or      pollutants and                                                                 concentration      standards                   discharge
                                     discharge       discharge          outlets                                               discharge                    discharge
 subsidiary        specific                                                                       (mg/L)         implemente                   approved
                                                      outlets                                                                     (t)
                  pollutants                                                                                      d (mg/L)                       (t/a)
                  Chemical
                   oxygen                                                                          88.3             240          70.95          213.6         Nil
  Livzon                                                               Sewage treatment
                   demand          Intermittent          1
Xinbeijiang                                                               workshop
                  Ammonia
                                                                                                      3.3            70          2.69            24.5         Nil
                   nitrogen
                Note: The discharge concentration represents the concentration of discharge into Qingyuan Henghe Sewage
                Treatment Plant (清远横荷污水处理厂), while the standard adopted for discharge represents the standard
                stipulated in the pollutant discharge license of the company, i.e. COD ≤240mg/L, ammonia nitrogen ≤70mg/L. The
                data was obtained from Qingyuan Environmental Protection Bureau.

                vii Livzon Hecheng
                                                                                                                 Pollutant
                      Name of                                                                                                                   Total
                                                          Number                               Discharge         discharge      Total
    Name of             major                                              Number of                                                          amount of
                                         Mode of             of                              concentration       standards    amount of                    Excessive
  company or        pollutants and                                         discharge                                                          discharge
                                         discharge        discharg                            (mg/L)/(mg/      implemented    discharge                    discharge
   subsidiary          specific                                             outlets                                                           approved
                                                          e outlets                               m3)          (mg/L)/(mg/        (t)
                      pollutants                                                                                                                 (t/a)
                                                                                                                    m3)
                     Chemical
                       oxygen                                                                    120              192           15.37           26.68         Nil
                                                                          Wastewater
                      demand
                                        Intermittent          1            treatment
                     Ammonia
                                                                             station
                      nitrogen                                                                   1.78              40           1.38            5.48          Nil
                      (NH3-N)
                       Sulfur
                                                              3           Boiler room             3                50           0.125             /           Nil
    Livzon             dioxide
   Hecheng            Nitrogen
                                                              3           Boiler room           74.85             150           2.051             /           Nil
                        oxide
                                       Organized
                     Particulate
                                       continuous             3           Boiler room            1.43              20           0.034             /           Nil
                       matter
                                       emission
                     Hydrogen
                                                              7            Workshop              2.29             100           0.829             /           Nil
                      chloride
                    Non-methane
                                                              7            Workshop             11.41              60           7.551           77.76         Nil
                    hydrocarbon


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                Joincare Pharmaceutical Group                                                                             Annual Report 2022


                   Non-methane
                                                               1           RTO               5.25                60         0.815                        Nil
                   hydrocarbon
                     Nitrogen
                                                               1           RTO                30                200         2.278            /           Nil
                      oxide
                      Sulfur
                                                               1           RTO                   3              200         0.467            /           Nil
                     dioxide

                Notes: 1. The discharge concentration of pollutants in waste water represents the average concentration by online
                monitoring from the master discharge outlet by the company into South District Sewage Treatment Plant, while the
                standard adopted for discharge represents the standard stipulated in the pollutant discharge license of the company,
                i.e. COD ≤192mg/L, ammonia nitrogen ≤40mg/L.
                2. The discharge concentration of pollutants in the discharge outlet of waste gas represents the average concentration
                detected by a qualified third party engaged, of which the boiler exhaust adopted the Emission Standard for Boiler
                Atmospheric Pollutants in Guangdong Province (DB 44/765-2019) (《广东省锅炉大气污染物排放标准》(DB
                44/765-2019)). The workshop and wastewater treatment station emission complied with the “Air Pollutant Discharge
                Standards for Pharmaceutical Industry” (《制药工业大气污染物排放标准》) (GB 37823-2019).

                viii Gutian Fuxing
                 Name of                                                                                 Pollutant                        Total
                                                     Number
  Name of          major                                            Number of          Discharge         discharge     Total amount     amount of
                                   Mode of              of                                                                                           Excessive
company or       pollutants                                         discharge        concentration       standards     of discharge     discharge
                                   discharge        discharge                                                                                        discharge
 subsidiary     and specific                                         outlets            (mg/L)         implemented          (t)         approved
                                                     outlets
                 pollutants                                                                               (mg/L)                           (t/a)
                 Chemical
                  oxygen                                            Southeastern          46.37            120            11.274           108          Nil
  Gutian
                  demand          Continuous           1             part of the
  Fuxing
                 Ammonia                                            factory zone
                                                                                          9.80             35             2.381           31.5          Nil
                  nitrogen
                Note: The discharge concentration represents the concentration of ultimate discharge into the environment, while
                the standard adopted for discharge represents the standard stipulated in the pollutant discharge license of the
                company, i.e. COD ≤120mg/L, ammonia nitrogen ≤35mg/L.

                ix Livzon Limin
                   Name of                                                                               Pollutant                        Total
                                                        Number
   Name of           major                                            Number of        Discharge         discharge     Total amount     amount of
                                      Mode of              of                                                                                        Excessive
 company or      pollutants and                                       discharge       concentratio       standards     of discharge     discharge
                                      discharge        discharge                                                                                     discharge
  subsidiary        specific                                           outlets         n (mg/L)        implemented          (t)         approved
                                                        outlets
                   pollutants                                                                             (mg/L)                           (t/a)
                   Chemical
                    oxygen                                            Wastewater          19.00           110              4.86            Nil          Nil
   Livzon
                    demand           Intermittent          1           treatment
   Limin
                   Ammonia                                               station
                                                                                          0.51             15              0.14            Nil          Nil
                    nitrogen
                Note: The wastewater of Livzon Limin was discharged into Shaoguan Second Sewage Treatment Plant (韶关市第
                二污水处理厂) and the standard adopted for pollutant discharge represented the standard stipulated in the pollutant
                discharge license of the company, i.e. COD ≤110mg/L, ammonia nitrogen ≤15mg/L, while the data detected by third
                party inspection was adopted as the discharge concentration.


                x Livzon Pharmaceutical Factory
                     Name of                                                                               Pollutant                       Total
                                                         Number
    Name of            major                                            Number of        Discharge         discharge        Total        amount of
                                       Mode of              of                                                                                        Excessive
  company or         pollutants                                         discharge      concentration       standards     amount of       discharge
                                       discharge        discharge                                                                                     discharge
   subsidiary       and specific                                         outlets          (mg/L)         implemented    discharge (t)    approved
                                                         outlets
                     pollutants                                                                             (mg/L)                          (t/a)
                     Chemical                                          Wastewater
                      oxygen                                1           treatment          17.65            120             2.22            Nil          Nil
   Livzon
                      demand                                              station
Pharmaceutical                        Intermittent
                                                                       Wastewater
   Factory           Ammonia
                                                            1           treatment           0.10             20             0.012           Nil          Nil
                     nitrogen
                                                                          station
                Note: The discharge concentration of pollutants in the wastewater discharge outlet represents the average
                concentration detected by a qualified third party engaged, by implementing the strictest of Schedule 2 Water
                Pollutant Discharge Concentration Limits for Newly-Built Enterprises (表 2 新建企业水污染物排放浓度限值) of
                the Emission Standard for Pharmaceutical Industrial Water Pollutants from Mixing and Formulation Category (《混
                装制剂类制药工业水污染物排放标准》) (GB 21908-2008), Schedule 2 Water Pollutant Discharge Concentration
                Limits for Newly-Built Enterprises ( 表 2 新建企业水污染 物 排放浓度 限值 ) of “Discharge Standards for
                Biopharmaceutical Industrial Wastewater” (《生物工程类制药工业水污染物排放标准》) (GB 21907-2008), and



                                                                                    101
                 Joincare Pharmaceutical Group                                                                                  Annual Report 2022


                 the level 1 of phase II standard of “Guangdong Provincial Capping on Polluted Effluents Discharge” (《广东省水
                 污染物排放限值》) (DB44/26–2001).

                 xi Ningxia Pharmaceutical
                                                                                                                    Pollutant                     Total
                      Name of                                                                                                       Total
                                                          Number                                                    discharge                    amount
    Name of             major                                             Number of           Discharge                            amount
                                         Mode of             of                                                     standards                       of       Excessive
  company or        pollutants and                                        discharge          concentration                            of
                                         discharge       discharge                                                implemented                   discharge    discharge
   subsidiary          specific                                            outlets          (mg/L)/(mg/m3)                        discharge
                                                          outlets                                                 (mg/L)/(mg/                   approved
                      pollutants                                                                                                      (t)
                                                                                                                       m3)                         (t/a)
                      Chemical                                              Sewage
                       oxygen                                              treatment              108                  200          110.47         Nil          Nil
                      demand                                             workshop on
                                                                1
                                                                         the north side
                      Ammonia
                                                                         of the factory           0.6                  25               0.74       Nil          Nil
                      nitrogen
                                                                              zone
                        Sulfur
                                                                                                     92                200          24.46        156.816        Nil
                       dioxide                                              Boiler
   Ningxia             Nitrogen                                          workshop on
                                        Continuous              1                                 138                  200          72.72        156.816        Nil
Pharmaceutical          oxide                                            north side of
                      Particulate                                        factory zone
                                                                                                     14                30               6.11     23.522         Nil
                        matter
                                                                          4 outlets for
                                                                        fermentation, 3
                       Volatile
                                                                           outlets for
                       organic                                  9                                 2.2                  100              5.38     79.535         Nil
                                                                         refinery and 2
                     compounds
                                                                           outlets for
                                                                             sewage

                 Notes: 1. The discharge concentration of wastewater represents the concentration of ultimate discharge to the
                 environmental protection control center of Ningxia Xin'an Technology Co., Ltd. (宁夏新安科技有限公司) (“Xin'an
                 Company”). The standard adopted for pollutant discharge was the standard stipulated in the pollutant discharge
                 license of the company and the amount of discharge was calculated by the amount received by Xin'an Company. In
                 respect of the total amount of approved discharge, since Ningxia Pharmaceutical adopted indirect discharge, the
                 local government of Ningxia cancelled the limitation of total discharge of chemical oxygen demand and ammonia
                 nitrogen of all indirect discharge enterprises, and the total amount index was directly allocated to sewage treatment
                 plants in the pharmaceutical industrial park established by the government after the renewal of the pollution
                 discharge license.
                 2. The emission concentration of boiler exhaust gas represents the self-monitoring average concentration throughout
                 the year, the standard adopted for discharge was the standard stipulated in the pollutant discharge license of the
                 company and the amount of discharge was calculated by the amount indicated by online monitoring. The
                 concentration of volatile organic compounds (VOCs) represents the concentration of ultimate discharge to the
                 environment (self-monitoring concentration). The adopted standard was the standard limits stipulated in Schedule I
                 of the “Air Pollutant Discharge Standards for Pharmaceutical Industry” (《制药工业大气污染物排放标准》)
                 (GB37823-2019) and the amount of discharge was calculated by the amount of exhaust gas emissions and the
                 discharge concentration recorded by the monitoring report.

                 xii Jiaozuo Hecheng
                    Name of                                                                                    Pollutant                         Total
                                                        Number
    Name of           major                                             Number of          Discharge           discharge         Total         amount of
                                       Mode of             of                                                                                               Excessive
  company or      pollutants and                                        discharge         concentratio         standards      amount of        discharge
                                       discharge       discharge                                                                                            discharge
   subsidiary        specific                                            outlets           n (mg/L)          implemented     discharge (t)     approved
                                                        outlets
                    pollutants                                                                                  (mg/L)                            (t/a)
                    Chemical
                                                                     Master outlet in
                     oxygen                                                                 99.213               220            8.037            60.8          Nil
   Jiaozuo                                                             industrial
                     demand           Continuous            1
   Hecheng                                                            wastewater
                    Ammonia
                                                                       workshop              3.483               35             0.281             8.8          Nil
                     nitrogen
                 Note: The discharge concentration and the total amount of discharge represent the concentration and total amount
                 of ultimate discharge into the downstream sewage treatment plant, and the source is online monitoring data.

                 xiii Shanghai Livzon
                 Name of                                                                                     Pollutant                           Total
                                                      Number                           Discharge
  Name of          major                                             Number of                               discharge       Total amount      amount of
                                    Mode of              of                          concentration                                                           Excessive
company or       pollutants                                          discharge                               standards       of discharge      discharge
                                    discharge        discharge                        (mg/L)/(mg/                                                            discharge
 subsidiary     and specific                                          outlets                              implemented             (t)         approved
                                                      outlets                             m3)
                 pollutants                                                                               (mg/L)/(mg/m3)                          (t/a)
                 Chemical
 Shanghai                                                           Master outlet
                  oxygen           Intermittent         1                                 39.92                50                3.30            6.291          Nil
  Livzon                                                             in the park
                  demand

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               Joincare Pharmaceutical Group                                                                              Annual Report 2022


               Ammonia
                                                                                        4.72               5-8            0.38           0.923         Nil
               nitrogen
                                                                  No. 5 and 6
               Particulate
                                                      2          outlets on the           -                 -             0.008          0.054         Nil
                 matter
                                  Organized                            roof
                                 intermittent                    No.1, 2, 3, 4,
                 Volatile
                                  discharge                      7, 8, 9 and 10
                 organic                              8                                 1.35               60             0.03            0.82         Nil
                                                                 outlets on the
               compounds
                                                                       roof
               Note: The discharge concentration was the average of monthly third-party monitoring data, and the amount of
               discharge was the cumulative sum of monthly discharge. The discharge of VOCs and particulate were in accordance
               with the “Air Pollutant Discharge Standards for Pharmaceutical Industry” (《制药工业大气污染物排放标准》)
               (GB37823-2019), and the discharge of COD and Ammonia nitrogen were implemented in accordance with the
               comprehensive sewage discharge standard DB31/199-2018. Shanghai Livzon was among other key pollutant
               discharge units, but not among the key pollutant discharge units of water environment and atmospheric environment.


               xiv Livzon MAB
                  Name of                                                                                 Pollutant                     Total
                                                     Number
  Name of           major                                            Number of           Discharge        discharge       Total       amount of
                                     Mode of            of                                                                                        Excessive
company or      pollutants and                                       discharge          concentratio      standards    amount of      discharge
                                     discharge      discharge                                                                                     discharge
 subsidiary        specific                                           outlets            n (mg/L)       implemented   discharge (t)   approved
                                                     outlets
                  pollutants                                                                               (mg/L)                        (t/a)
                  Chemical                                           Wastewater
                   oxygen                                 1           treatment            17.65           120            2.88           Nil         Nil
  Livzon           demand                                               station
                                    Intermittent
  MAB                                                                Wastewater
                  Ammonia
                                                          1           treatment               0.10          20           0.016           Nil         Nil
                  nitrogen
                                                                        station
               Note: The discharge concentration of pollutants in the wastewater discharge outlet represents the average
               concentration detected by a qualified third party engaged, by implementing the strictest of Schedule 2 Water
               Pollutant Discharge Concentration Limits for Newly-Built Enterprises (表 2 新建企业水污染物排放浓度限值) of
               the “Emission Standard for Pharmaceutical Industrial Water Pollutants from Mixing and Formulation Category”
               (《混装制剂类制药 工业水污 染物排放标准》) (GB 21908-2008), Schedule 2 Water Pollutant Discharge
               Concentration Limits for Newly-Built Enterprises (表 2 新建企业水污染物排放浓度限值) of “Discharge Standards
               for Biopharmaceutical Industrial Wastewater” (《生物工程类制药工业水污染物排放标准》) (GB 21907-2008),
               and the level 1 of phase II standard of “Guangdong Provincial Capping on Polluted Effluents Discharge” (《广东省
               水污染物排放限值》) (DB44/26–2001).

               xv Sichuan Guangda
                   Name of                                                                                Pollutant                     Total
                                                      Number                                                             Total
   Name of           major                                            Number of           Discharge       discharge                   amount of
                                      Mode of            of                                                            amount of                  Excessive
 company or      pollutants and                                       discharge          concentratio     standards                   discharge
                                      discharge      discharge                                                         discharge                  discharge
  subsidiary        specific                                           outlets            n (mg/L)      implemented                   approved
                                                      outlets                                                              (t)
                   pollutants                                                                              (mg/L)                        (t/a)
                   Chemical
                    oxygen                                            Wastewater              35.85         500           3.26           Nil         Nil
  Sichuan
                    demand           Intermittent         1            treatment
  Guangda
                   Ammonia                                               station
                                                                                              1.61              45        0.15           Nil         Nil
                    nitrogen
               Note: The wastewater of Sichuan Guangda was discharged into Pengzhou First Sewage Treatment Plant (彭州市第
               一污水处理厂) and the standard adopted for pollutant discharge represented the standard stipulated in the pollutant
               discharge license of the company, i.e. COD ≤500mg/L, ammonia nitrogen ≤45mg/L, while the discharge
               concentration of pollutants in the wastewater discharge outlet represents the average concentration detected by a
               qualified third party engaged.


               2. Construction and operation of pollution preventive facilities
               √ Applicable □ N/A

                 Name of company or
                                                              Construction and operation of pollution preventive facilities
                    subsidiary
                                                 Exhaust gas: The treatment process of “water spray + acid spray + alkali spray + mist
                                                 eliminator + dry filter + adsorption concentrator + RCO” + “secondary alkali spray”
                    Jiaozuo Joincare             was adopted for fermentation exhaust gas. The treatment process of “bag type dust
                                                 collector” was adopted for proportioning process dust-laden exhaust gas. The
                                                 treatment process of “secondary alkali spray” was adopted for exhaust gas treatment


                                                                                  103
Joincare Pharmaceutical Group                                                                 Annual Report 2022


                         facilities in wastewater treatment station. The treatment process of “alkali adsorption”
                         was adopted for process acid waste gas. The treatment process of “tertiary finned
                         condenser + bag type dust collector + secondary alkali spray + RTO”/“-20 ℃
                         condensation + activated carbon adsorption device (including regenerating device) +
                         RTO”/“adsorption device (including regenerating device) Jiaozuo Joincare +
                         secondary alkali spray + biological uptake + secondary alkali spray”/“secondary alkali
                         spray + biological uptake + secondary alkali spray” was adopted for process organic
                         exhaust gas. 15 discharge outlets were constructed. All of them enable stable and up-
                         to-standard discharge through self-monitoring in 2022.
                         Wastewater: The treatment process of “regulating pool + hydrolysis acidification pool
                         + UASB + (CASS + air flotation) / modified A/O + secondary settling tank +
                         coagulating sedimentation” was primarily adopted. Standard wastewater outlets were
                         set; online automatic monitoring control system was installed at outlets for real-time
                         monitoring of COD, ammonia nitrogen, total nitrogen, pH, fluorion and flow.
                         Wastewater treatment process sections can be stably operated. Moreover, wastewater
                         control factors can be stably emitted in compliance with the required standard.
                         Pollution preventive facilities functioned properly and ensured up-to-standard
 Taitai Pharmaceutical
                         discharge.
                         A set of laboratory exhaust gas treatment system was set up and functioned properly.
    Haibin Pharma        Pollution preventive facilities functioned properly and ensured up-to-standard
                         discharge.
                         Wastewater: The wastewater treatment system with daily processing capacity of 600
                         tonnes through patented H/O process designed by East China University of Science
                         and Technology started operation in April 2016 and functioned properly in 2022. In
                         March 2022, a set of lift aerator system and a set of magnetic levitation blower were
                         added in the biochemical system, and they have been put into operation and
                         functioning properly at present. A new sewage anaerobic treatment system had been
                         building and is under debugging. The H/O biochemical system increased two
                         nitrification reflux pumps of 100m3/h through upgrading and constantly functioned
                         properly.
                         Exhaust gas: The 40000m/h regenerative oxidation exhaust gas treatment system
    Xinxiang Haibin      designed by Jiangsu Ruiding started operation on 2 November 2019, functioned
                         properly throughout 2022 and was emitted in compliance with the required standard.
                         After reconstruction of dry tail gas self-circulating process, the activated carbon
                         adsorption device designed by Beijing Rixin Daneng Technology Co., Ltd. functioned
                         properly in 2022. After UV photolysis+two-level alkali spray and one-level water
                         spray treatment, the waste gas from biochemical aerobic process of wastewater
                         treatment was emitted in compliance with the required standard. The organic waste
                         gas from the workshop process was recycled by membrane and then by resin, and
                         finally delivered into the RTO waste gas treatment system, it ran normally in 2022.
                         The resin recovery organic waste gas pretreatment facilities were completed and run
                         normally.
                         The company strictly complies with the “Three-Simultaneous” system of
                         environmental protection by collecting and treating “Three Wastes (waste water,
                         exhaust gas and solid waste)” according to requirements, and employs an advanced
                         wastewater treatment process known as “Regulating pool + Hydrolysis acidification
                         tank + Sequencing Batch Reactor Activated Sludge Process (SBR) + Air float”. After
                         the wastewater from production has gone through the above treatment process, all
    Fuzhou Fuxing        indicators are stable and satisfy the discharge standard. After meeting the discharge
                         standards, the wastewater is discharged to Jiangyin sewage treatment plant operated
                         by Fujian Huadong Water Treatment Co., Ltd. (福建华东水务有限公司) via sewage
                         pipe network at the industrial park area for further treatment. In 2022, the waste gas
                         treatment facilities for Fenton pool and regulating pool have been added, and the waste
                         gas was treated by secondary spraying.
                         The “Three Wastes” were collected and treated effectively in strict compliance with
                         the “Three Simultaneous” system. The sewage treatment facilities with an investment
                         amount of over RMB30 million have a designed processing capacity of 3,000t/d and
                         adopt the treatment process of “Pre-treatment + Aerobic pool + Hydrolysis
                         acidification tank + SBR + Catalytic oxidation + Air float”. In the first half of 2022,
                         the third round of environmental protection improvement has been carried out,
  Livzon Xinbeijiang
                         including replacing biological deodorization boxes of the sewage station, adding spray
                         towers and reinstalling pretreatment waste gas collection pipeline to reduce the
                         fugitive emission of waste gas, which has greatly eliminated the peculiar smell around
                         the sewage station. Mufflers were installed at the air emission outlets of the sewage
                         station and the second fermentation division to reduce the airflow sound of air
                         emissions. Sound-absorbing cotton panels have been used to surround the circulating


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Joincare Pharmaceutical Group                                                                Annual Report 2022


                         pump and steam compressor of the MVR, which have greatly reduced the noise
                         transmitted by the MVR. Meanwhile, equipment with loud noises has been surrounded
                         by sound-absorbing cotton panels to reduce noise and control the generation and
                         transmission of noise from the source.
                         The “Three Wastes” were treated in a centralized and effective manner in strict
                         compliance with the “Three Simultaneous” system and the maintenance and
                         management of pollution preventive facilities were enhanced to ensure that pollutant
                         discharge was stable and in compliance with the required standard. The treatment
                         process of “pre-treatment of drainage from the production process + hydrolytic
    Livzon Hecheng       acidification + Upflow Anaerobic Sludge Bed (UASB) + advanced oxidation + Cyclic
                         Activated Sludge System (CASS) process + air floatation/ozonation advanced
                         treatment” was adopted. Treated sewage was discharged through the municipal sewage
                         pipeline network into Zhuhai Leaguer Environmental Protection Co., Ltd. (珠海力合
                         环保有限公司) (water purification plant in the South District).
                         At the same time when the enterprise started production, the “Three Wastes” were
                         collected and treated effectively in accordance with the requirements of the “Three
                         Simultaneous” system of environmental protection. This involves a designed sewage
                         treatment capacity of 1,200 t/d, adoption of the advanced “Anarerobic-Oxic activated
                         sludge process (A/O) + SBR + nitrogen removal by denitrification + Fenton
                         decolorizing + air flotation” wastewater treatment process, 6,000 m3 of effective
                         reservoir capacity of the treatment system and more than 20 sets of treatment
     Gutian Fuxing
                         equipment with 350 KW installed capacity to improve the water treatment process,
                         thus ensuring that all wastewater treatment indicators are stable and satisfy the
                         discharge standard. Treated sewage that reaches the grade II discharge standard is
                         directly discharged into Minjiang River. The hazardous waste of the company is
                         entrusted to qualified companies for compliant disposal according to the requirements
                         of environmental impact assessment and acceptance inspection opinions. In 2022,
                         boiler air pollutant treatment facilities were upgraded and reconstructed.
                         The “Three Simultaneous” system was strictly implemented by the company for the
                         treatment of “Three Wastes” by collecting and treating the “Three Wastes” effectively.
                         The original sewage treatment plant with an investment amount of over RMB13
                         million has a designed processing capacity of 1,500t/d and adopts the treatment
                         process of “Pre-treatment + Hydrolysis acidification tank + Facultative tank + Aerobic
                         pool + Secondary sedimentation”, and the sewage after treatment was discharged
     Livzon Limin
                         through the municipal pipeline network into Shaoguan Second Sewage Treatment
                         Plant (韶关市第二污水处理厂). In respect of waste gas treatment, biomass boilers
                         were all replaced by gas boilers. The technical transformation project of the R&D
                         center has installed waste gas treatment facilities such as activated carbon adsorption
                         and acid mist spray tower. In respect of control of noise pollution, investment was
                         made to construct noise segregation wall to reduce noise pollution.
                         The “Three Simultaneous” system was strictly implemented by the company for the
                         treatment of “Three Wastes” by collecting and treating the “Three Wastes” effectively.
                         For wastewater: an investment of over RMB10 million was made for phase I and phase
                         II sewage treatment station with a designed processing capacity of 1,000t/d, which
       Livzon
                         adopted the CASS process for phase I and the A/O process for phase II, and the sewage
    Pharmaceutical
                         after treatment was discharged through the municipal pipeline network into sewage
       Factory
                         treatment plants. For waste gas: currently, the company uses purchased steam and
                         takes the boilers as backups, greatly reducing air emissions. The waste gas of the
                         wastewater treatment stations is treated by a combination of first-level spray towers,
                         Ultra Violet (UV) photoion equipment and second-level spray towers.
                         Through strict enforcement of the “Three Simultaneous” system, the “Three Wastes”
                         were collected and treated effectively. The designed total processing capacity of
                         sewage treatment was 7,500 m3/d (including one plant with capacity of 5,000 m3/d and
                         one plant with capacity of 2,500 m3/d), and the actual total treatment amount was 3,100
                         m3/d. Treated sewage that reaches the standard stipulated in the pollutant discharge
                         license is discharged to Xin’an Company through the sewage pipeline network in the
                         industrial park. In 2021, the installation and use of waste gas collection and treatment
       Ningxia           facilities for hazardous waste stations were completed, and doramectin fermentation
    Pharmaceutical       waste gas of fermentation workshop 101 was introduced into the specific waste gas
                         treatment facilities for doramectin fermentation waste gas of fermentation workshop
                         102, and a primary sedimentation tank was added to the sewage treatment station to
                         lead out waste gas for treatment. In 2022, the construction of the following pollution
                         prevention and control facilities was mainly completed: 1. Construction of the exhaust
                         sampling port and sampling platform of the waste gas collection and treatment facility
                         in the hazardous waste storage vault; 2. Renovation of the fresh air supply facility in
                         the bacteria residue crushing room. The original fresh air supply fan installed in the


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Joincare Pharmaceutical Group                                                                Annual Report 2022


                         middle of the wall was moved to the bottom of the wall, and installation of a new fresh
                         air supply fan; 3. Upgrade and improvement of the original waste gas treatment
                         facilities in 103-2 fermentation workshop, mainly including a new set of "sodium
                         hypochlorite spray absorption + water spray absorption + biphasic superoxide water +
                         micro-nano bubbles" process treatment facilities; 4. Construction of anti-leakage
                         facilities in the emergency pool of hazardous chemicals warehouse; 5. Replacement of
                         damaged cover plate of sludge storage tank; 6. reseal the cover plate of the sewage
                         treatment pre-aeration tank and seal and repair of the water-sealing groove of the cover
                         plate of the sedimentation tank, sealing the original cover plate of the pre-aeration tank
                         integrally with glass fiber cloth and epoxy resin, applying paint on the rusted pipeline,
                         and welding and plugging the damaged part of the water-seal groove of the cover plates
                         of original sedimentation tank; 7. the construction of rainwater and sewage diversion
                         facilities in the plant area, and laying and installing rainwater collection pipe network
                         facilities with a total length of about 1,000 meters.
                         The “Three Wastes” were collected and treated effectively in strict compliance with
                         the “Three Simultaneous” system. The designed sewage treatment capacity was
                         3,000t/d, the treatment process of “hydrolytic acidification tank + UASB + aerobic
                         pool + materialized treatment” was adopted, the treated wastewater would be
                         discharged through the municipal pipeline network into the sewage treatment plant of
                         Xiuwu Branch of Kangda Water Co., Ltd. (康达水务有限公司修武分公司). The
                         sewage treatment facilities were under normal operation with compliant discharge. For
                         waste gas: in 2021, the three-stage sewage spraying was replaced, and a set of waste
                         gas treatment facilities was added in the UV photolysis sewage station. Waste gas
                         would be discharged after standard was met. Waste gas generated from technical
                         process in the production zone would be collected and treated by adopting two sets of
                         processes of “water spray + activated carbon and -20℃ condensation + water spray +
                         activated carbon” and then discharged after reaching the required standard. Solid waste
                         and hazardous waste would be stored in the hazardous waste station constructed in
                         compliance with the requirements of “Three Protections” (protection against leaks,
                         erosion and rain) according to the requirements under the (Pilot) Guidelines for
                         Standardized Management of Hazardous Waste in Henan Province (《河南省危险废
   Jiaozuo Hecheng       物规范化管理工作指南(试行)》) for hazardous waste. In January 2022, a self-
                         monitoring and automatic monitoring equipment comparison contract was signed with
                         Henan Zhongfang Quality Inspection Technology Co., Ltd. (河南中方质量检测技术
                         有限公司) to monitor the company’s discharge outlets on a regular basis; in January
                         2022, an operation and maintenance contract in relation to online continuous
                         monitoring system for water quality was signed with Jiaozuo Lansheng Environmental
                         Technology Service Co., Ltd. (焦作市蓝晟环保技术服务有限公司) to maintain the
                         water quality by the company’s online continuous monitoring system. In April 2022,
                         the company entered into a hazardous waste disposal agreement with Henan
                         Zhonghuanxin Environmental Technology Co., Ltd. (河南中环信环保科技有限公
                         司) for disposal of hazardous waste on regular basis. Other general solid waste would
                         be disposed of in compliance with the relevant requirements. In March 2022, we
                         signed a wastewater discharge water quality standard agreement with Kangda
                         Environmental Protection Water Co., Ltd. (康达环保水务有限公司) Xiuwu Branch,
                         and in the same month, we signed an LDAR test agreement with Shandong Xianglong
                         Environmental Testing Co., Ltd. In July 2022, we signed a gas online operation and
                         maintenance contract with Jiaozuo City Kailin Environmental Protection Technology
                         Co., Ltd. (焦作市凯霖环保科技有限公司).
                         The company designed and built a sewage treatment station with a processing capacity
                         of 200 m3/d in 2018. The company’s wastewater was treated by such sewage treatment
                         station and then entered the park’s sewage treatment station for secondary treatment,
                         and finally discharged into the municipal pipeline network. The company had the
                         hazardous waste station in compliance with the requirements of “Three Preventions”
                         to store hazardous waste and appointed a qualified company for compliant disposal.
    Shanghai Livzon
                         The company’s main discharge outlets were treated with activated carbon adsorption
                         and filtration, and the activated carbon was replaced every half a year to ensure that
                         the air emissions met the standards. In January 2022, the company demolished the
                         solid preparation workshop on the third floor and transformed it into a microsphere
                         workshop, and there is no particulate matter emission from the No. 5 and No.6
                         discharge outlets accordingly.
                         The “Three Simultaneous” system was strictly implemented by the company for the
                         treatment of “Three Wastes” by collecting and treating the “Three Wastes” effectively.
     Livzon MAB
                         For wastewater (relying on the wastewater treatment of Pharmaceutical Factory in the
                         park): an investment of over RMB10 million was made for phase I and phase II sewage


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Joincare Pharmaceutical Group                                                                  Annual Report 2022


                          treatment station with designed processing capacity of 1,000t/d, which adopted the
                          CASS process for phase I and the A/O process for phase II, and the sewage after
                          treatment was discharged through the municipal pipeline network into sewage
                          treatment plants. For waste gas: currently, the company uses purchased steam and
                          takes the boilers as backups, greatly reducing air emissions. The waste gas of the
                          wastewater treatment stations is treated by a combination of first-level spray towers,
                          Ultra Violet (UV) photoion equipment and second-level spray towers.
                          The “Three Simultaneous” system was strictly implemented by the company for the
                          treatment of “Three Wastes” by collecting and treating the “Three Wastes” effectively.
                          For wastewater (relying on the wastewater treatment station with an investment of over
                          RMB5 million and designed processing capacity of 400t/d, which adopted the process
                          of “Regulating pool+Anaerobic pool+Aerobic pool+Air float” forsewage treatment,
      Sichuan Guangda     the sewage after treatment was discharged through the municipal pipeline network into
                          Pengzhou No.1 Sewage Treatment Plant (彭州市第一污水处理厂). For waste gas:
                          currently, the company adopts biomass boiler with "cyclone + cloth bag
                          +SNCR+SCR" to treat the waste gas produced. The waste gas of sewage station is
                          treated by alkali washing spray.


3.  Environmental impact assessment of construction projects and other environmental
    protection administrative licensing
√Applicable □N/A

 Name of company or               Environmental impact assessment of construction projects and other
    subsidiary                              environmental protection administrative licensing
                          The Approval of Environmental Impact Report on New 12T Natural Gas Boiler Project
                          for Jiaozuo Joincare Pharmaceutical Industry Co., Ltd. (Jiao Huan Shen Ma [2022] No.
      Jiaozuo Joincare
                          2) was granted on 11 May 2022. The environmental protection inspection for the new
                          boiler project was carried out on 26 October 2022.
                          The environmental impact assessment report of new products was under the stage of
 Taitai Pharmaceutical
                          preparation and approval.
                          No environmental impact assessment project was required in 2022; with strict
                          enforcement of the “Three Simultaneous” system in the production process and
                          implementation of the environmental protection measures required under the
       Haibin Pharma
                          environmental impact assessment, the environmental protection facilities have been
                          functioning properly; the change of pollutant discharge license was applied for and
                          obtained approval in November 2022.
                          Approval of Environmental Impact Report on 20 Tonnes/Year Meropenem
                          Pharmaceutical Intermediate Project (Yu Huan Jian [2005] No. 84), Opinions on
                          Environmental Protection Inspection and Acceptance for 20 Tonnes/Year Meropenem
                          Pharmaceutical Intermediate F9 Project (Yu Huan Bao Yan [2008] No. 89), Approval
                          of Environmental Impact Report on 100 Tonnes/Year Meropenem Pharmaceutical
                          Intermediate Expansion Project (Yu Huan Shen [2014] No. 564), Independent
                          acceptance of Approval of Environmental Impact Report on 100 Tonnes/Year
      Xinxiang Haibin
                          Meropenem Pharmaceutical Intermediate Expansion Project on 24 March 2019, and
                          Opinions of Comprehensive Supervision and Enforcement Bureau of High-tech Zone on
                          Approval of Environmental Impact Report on Technical Center Expansion Project of
                          Xinxiang Haibin Pharmaceutical Co., Ltd. (Xin Gao Zong Jian Zi [2020] No. 26). The
                          reply to the Environmental Impact Assessment Report for the Peinan Series API
                          Development Project of Xinxiang Haibin Pharmaceutical Co., Ltd (Xin Huan Shu Shen
                          [2021] No. 24) was received.
                          The Environmental Impact Report on the Phase III High-end Antibiotics Project of
                          Livzon Group Fuzhou Fuxing Pharmaceutical Co., Ltd. was approved on 23 August
                          2021. The company strictly implements the “Three Simultaneous” system and takes
                          environmental protection measures required for environmental assessment, with the
                          environmental protection facilities under normal operation. Approval was granted for
      Fuzhou Fuxing       the application of a new national pollutant discharge license on 27 December 2017 and
                          the renewal of the national pollutant discharge license was completed in December 2020.
                          The company has been discharging pollutants in strict compliance with the licensing and
                          administrative requirements. The Environmental Impact Report on the Phase IV High-
                          end Antibiotics Project of Livzon Group Fuzhou Fuxing Pharmaceutical Co., Ltd. was
                          approved on 12 October 2022.
                          The “Environmental Impact Report on Current Status of Projects of Livzon Group
                          Xinbeijiang Pharmaceutical Manufacturing Inc.” (《(丽珠集团新北江制药股份有限
     Livzon Xinbeijiang
                          公司项目现状环境影响报告书》) was approved and filed on 6 December 2016. With
                          strict enforcement of the “Three Simultaneous” system and implementation of the

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Joincare Pharmaceutical Group                                                               Annual Report 2022


                         environmental protection measures required under the environmental impact
                         assessment, the environmental protection facilities have been functioning properly. On
                         29 December 2017, an approval was granted for the application of a new national
                         pollutant discharge license. The environmental protection policies were strictly
                         enforced. On 28 April 2022, the company completed the application for the pollutant
                         discharge license for Shijiao New Factory. On 16 June 2022, the company completed
                         the environmental impact assessment of the new plant for the addition of mixed
                         compound veterinary drugs and obtained the environmental assessment approval
                         (Qingcheng Shen Pi Huan Biao [2022] No. 12). The work for changing and renewing
                         the pollutant discharge license was completed in December 2022.
                         The “Environmental Impact Assessment Report on Current Status of the Product
                         Structure and Production Capacity Adjustment Project of Zhuhai FTZ Livzon Hecheng
                         Pharmaceutical Manufacturing Co., Ltd.” (《珠海保税区丽珠合成制药有限公司产品
                         结构及产能调整项目现状环境影响评价报告》) was approved in December 2016. In
                         2021, the environmental impact assessment of 14 new products including paliperidone
                         palmitate (棕榈酸帕利呱酮), aripiprazole (阿立哌唑), bismuth potassium citrate (枸橼
                         酸 铋 钾 ), i.e. the “Environmental Impact Assessment Report on Technological
   Livzon Hecheng        Renovation and Expansion Project of Livzon Synthetic Pharmaceutical Co., Ltd. in
                         Zhuhai Free Trade Zone” (《 珠海保税区丽珠合成制药有限公司技改扩建项目环境
                         影响评价报告》), passed expert review and was approved on 20 January 2022. The
                         company strictly enforced the “Three Simultaneous” system and implemented
                         environmental protection measures as required under environmental impact assessment
                         with normal operation of the environmental protection facilities. In 2022, it was awarded
                         the green card enterprise of environmental credit rating by Zhuhai Municipal Ecology
                         and Environment Bureau. In March 2022, the company completed the filing of the
                         revised environmental emergency contingency plan.
                         The company passed the environmental impact assessment on 30 June 1999 and the
                         inspection and acceptance upon completion of construction carried out by
                         Environmental Protection Bureau of Fujian Province on 5 June 2000. The company re-
                         prepared its post-environmental impact assessment report in 2019 and passed the
                         inspection and acceptance carried out by experts on 11 June 2019. The company strictly
    Gutian Fuxing        enforced the “Three Simultaneous” system and implemented environmental protection
                         measures as required under environmental impact assessment with normal operation of
                         the environmental protection facilities. The clean production passed the on-site audit and
                         acceptance by the Bureau of Ecology and Environment in September 2022, and the audit
                         and inspection opinion of the Ningde Environmental Science Institute was obtained in
                         October 2022.
                         The “Environmental Impact Report on the Technological Reform Project for the R&D
                         Center of Livzon Group Limin Pharmaceutical Manufacturing Factory” (《丽珠集团利
                         民制药厂研发中心技改项目环境影响报告表》) was approved on 6 December 2019.
                         The expert meeting of acceptance was held on 24 April 2021, in which the independent
                         acceptance was completed. The “Environmental Impact Report for Workshop II of Small
                         capacity Injection” (《小容量注射剂二车间项目环境影响报告表》) was approved on
                         23 November 2020. On 15 September 2021, the expert meeting of acceptance was held,
                         in which the independent review was completed. The National Sewage Permit was
     Livzon Limin        updated on 22 October 2021. The “Three Simultaneous” system was strictly enforced to
                         implement the environmental protection measures required under the environmental
                         impact assessment, and the environmental protection facilities were under normal
                         operation. In September 2022, Limin Pharmaceutical Manufacturing Factory passed the
                         on-site audit of cleaner production by the expert group. In the future, it will continue to
                         tap the potential of energy conservation and emission reduction, establish and improve
                         the cleaner production mechanism, and continuously improve the level of cleaner
                         production. From 2019 to 2022, it was consecutively rated as a green card enterprise by
                         Shaoguan Ecology and Environment Bureau.
                         The Environmental Impact Assessment Report on Expansion Project for Production
                         Line of Recombinant Human Chorionic Gonadotropin for Injection of Livzon Group
                         Livzon Pharmaceutical Factory (丽珠集团丽珠制药厂) was approved in March 2018.
                         The Environmental Impact Assessment Report on Expansion Project for Sewage
                         Treatment Stations of Livzon Group Livzon Pharmaceutical Factory was approved in
Livzon Pharmaceutical
                         April 2019. The Environmental Impact Assessment Report on Expansion Project for
       Factory
                         Production Line of lyophilized Powder Injection of Livzon Group Livzon
                         Pharmaceutical Factory was approved in November 2020. The Environmental Impact
                         Report Form of P07 New Wet Granulation Line Project of Livzon Group Livzon
                         Pharmaceutical Factory was approved on 18 May 2022. The pharmaceutical factory
                         obtained an updated sewage permit in June 2022. The Environmental Impact Report on


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Joincare Pharmaceutical Group                                                            Annual Report 2022


                         the Project of New Boiler and Low Nitrogen Transformation of Boiler was approved on
                         19 August 2022. The company will strictly enforce the “Three-simultaneous” system to
                         implement the environmental protection measures as required by environmental
                         assessment.
                         The environmental protection inspection for completion of doramectin expansion project
                         was completed in March 2021. In September 2021, expert review and government filing
                         were completed for the environmental impact evaluation of project work upon optimized
                         disposal of the company’s solid waste. The company applied to change its pollutant
                         discharge permit and passed the review of the Pingluo Branch of Shizuishan Municipal
                         Ecology and Environment Bureau in December 2021. In December 2022, the company
                         passed the certification of Shizuishan municipal green plant and prepared the
                         environmental impact assessment report on the increase in production capacity of
Ningxia Pharmaceutical   phenylalanine (currently under review by experts). The company reported to the national
                         pollution discharge license management information platform (pollution discharge
                         implementation report) and the ecological environment statistics business system
                         (enterprise environment statistics report) quarterly. In 2022, the second round of
                         rectification of central environmental protection supervision issues, independent
                         acceptance by enterprises and government acceptance were also completed. The
                         company strictly enforced the “Three Simultaneous” system to implement the
                         environmental protection measures as required by environmental assessment, while the
                         environmental protection facilities were under normal operation.
                         The “Environmental Impact Assessment Report on Current Status of Jiaozuo Livzon
                         Hecheng Pharmaceutical Manufacturing Co., Ltd.” (《焦作丽珠合成制药有限公司现
                         状环境影响评估报告》) was approved and filed on 15 December 2016. The “Three
                         Simultaneous” system was strictly enforced, the environmental protection measures as
                         required by environmental assessment were implemented and the environmental
                         protection facilities were under normal operation. The application for the national
   Jiaozuo Hecheng       pollutant discharge license was completed in December 2020, the environmental
                         protection policies were strictly enforced and various management measures were
                         implemented. According to the spirit of the document “Notice of the Office of the
                         Leading Group of Jiaozuo City’s Pollution Prevention and Control Battle on Doing a
                         Good Job in the Key Work of Air Pollution Prevention and Control in May 2022”, the
                         company formulated the “one policy for one enterprise” plan for Jiaozuo Hecheng VOCs
                         emission enterprise in 2022. In May 2022, the letter of commitment for environmental
                         protection and law-abiding operation of enterprises for 2022 was formulated.
                         The company passed the environmental assessment review of the “Leuprorelin Acetate
                         Microspheres for Injection Industrialization Project” (《注射用醋酸亮丙瑞林微球产
                         业化项目》) on 11 October 2010, obtained the approval for the “Environmental Impact
                         Report on Supporting Engineering and Laboratory Projects of Shanghai Livzon
   Shanghai Livzon       Pharmaceutical Manufacturing Co., Ltd.” (《上海丽珠制药有限公司配套工程及实验
                         室项目环境影响报告》 on 10 January 2020, and completed the construction and passed
                         the acceptance inspection in September 2020. The company strictly implemented the
                         “Three Simultaneous” system and took environmental protection measures required for
                         environmental assessment, while the environmental protection facilities were under
                         normal operation.
                         The “Environmental Impact Assessment Report on V-01 Industrialization Project of
                         Livzon Group Livzon Pharmaceutical Factory” (《关于丽珠集团丽珠制药厂 V-01 产
                         业 化 项 目 环 境 影 响 报 告 书 》 ) was approved in April 2021. The Third Line
                         Environmental Impact Report of the Expanded Preparation of the Large-scale
     Livzon MAB          Production Capacity Construction Project of Recombinant SARS-CoV-2 Fusion Protein
                         Vaccine (V-01) was approved in March 2022. The company obtained an updated sewage
                         permit in November 2022. The company strictly implemented the “Three Simultaneous”
                         system and took environmental protection measures required for environmental
                         assessment.
                         The “Filing Report of Environmental Impact on the Technical Upgrading Project of
                         Production Line for Chinese Patent Medicine of Sichuan Guangda Pharmaceutical
                         Manufacturing Co., Ltd.” (《四川光大制药有限公司中成药生产线技术改造项目环
   Sichuan Guangda       境影响备案报告》) was approved and filed on 27 May 2016, and was granted a national
                         pollutant discharge license on 23 July 2020. The company strictly implemented the
                         “Three Simultaneous” system and took environmental protection measures required for
                         environmental assessment, and the environmental protection facilities were under
                         normal operation.




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Joincare Pharmaceutical Group                                                              Annual Report 2022


4. Environmental emergency contingency plan
√ Applicable □ N/A

Name of company or
                                             Environmental emergency contingency plan
   subsidiary
                        Revision of the environmental emergency contingency plan of Jiaozuo Joincare was
                        completed in May 2022 and was filed in the Macun Branch of Ecology and Environment
                        Bureau of Jiaozuo City on 19 May 2022.
  Jiaozuo Joincare
                        Revision of the environmental emergency contingency plan for hazardous waste pollution
                        accident of Jiaozuo Joincare was completed in December 2020, which currently is in
                        effect.
Taitai Pharmaceutical   Review and filing was completed in July 2020, which currently is in effect.
                        The Environmental Emergency Contingency Plan was filed (File No. 440308-2020-
                        0029M). Trainings and drills on emergency responses were provided for employees to
   Haibin Pharma
                        improve the capability of the Company for dealing with environmental emergencies. In
                        2022, four emergency drills for environmental emergencies were held.
                        Environmental Emergency Contingency Plan of Xinxiiang Haibin Pharmaceutical Co.,
  Xinxiang Haibin       Ltd. was filed with the Ecology and Environment Bureau on 23 August 2022 with the file
                        reference number 410771-2022-006-M.
                        Pursuant to relevant provisions and requirements, the “Environmental Emergency
                        Contingency Plan of Livzon Group Fuzhou Fuxing Pharmaceutical Co., Ltd.” (《(丽珠
                        集团福州福兴医药有限公司突发环境事件应急预案》) was prepared based on the
                        principles of “prevention-oriented, self-help-oriented, unified command, and division of
                        responsibility”, which has been filed on 15 April 2022 (File No. 350181-2022-024-M).
                        After environmental emergencies occur, immediate, quick, effective and orderly
   Fuzhou Fuxing        emergency rescue actions shall be taken to control and prevent the spread of accident and
                        contamination, protect the surrounding environment and safeguard life and property of all
                        employees, the company and nearby communities. In accordance with the contents and
                        requirements of the plan, the company provides trainings and drills for its employees to
                        get them well-prepared for environmental emergencies, so that timely rescue can be taken
                        and the accident can be controlled in a short period of time in case of any environmental
                        emergencies. In May 2022, the second comprehensive emergency drill for four leakage
                        accidents in the workshop was conducted.
                        Based on the principles of “prevention-oriented, on-alert all the time; classified
                        management, level-by-level response; cross-department cooperation, responsibility by
                        levels; scientific prevention and efficient handling”, Livzon Xinbeijiang re-signed and
                        issued the “Environmental Emergency Contingency Plan of Livzon Group Xinbeijiang
                        Pharmaceutical Manufacturing Inc.” (《(丽珠集团新北江制药股份有限公司突发环境
 Livzon Xinbeijiang     事件应急预案》) (File No. 441802-2021-0162-H) on 30 September 2021, which has been
                        approved and filed by Qingyuan Municipal Ecology and Environment Bureau on 22
                        October 2021. Livzon Xinbeijiang conducted exercises regularly to identify environmental
                        factors and sources of hazards, as well as drills on the emergency contingency plan. An
                        environmental emergency contingency drill was conducted in June 2022 to improve the
                        operability thereof, and enhance the performance of the emergency rescue staff and the
                        responsiveness and coordination ability of the rescue team.
                        Pursuant to relevant provisions and requirements, the “Environmental Emergency
                        Contingency Plan of Zhuhai FTZ Livzon Hecheng Pharmaceutical Manufacturing Co.,
                        Ltd.” (《(珠海保税区丽珠合成制药有限公司突发环境事件应急预案》) was prepared
                        based on the principles of “Focus on Prevention, Aim at Self-rescue, Centralized
                        Command, and Division of Responsibility”, which has been approved, filed and issued
  Livzon Hecheng
                        (File No. 440462-2019-001-M). Trainings on emergency response and handling measures
                        were held regularly for employees to enable implementation of safety measures in a timely,
                        fast, effective and orderly manner to control and prevent the spread of accident and
                        contamination when encountering any environmental emergencies, so as to alleviate or
                        eliminate the impact of the accident and resume production as soon as possible.
                        Pursuant to relevant provisions and requirements, the “Environmental Emergency
                        Contingency Plan of Gutian Fuxing Pharmaceutical Co., Ltd.” (《古田福兴医药有限公
                        司突发环 境事 件应急 预案》 ) was prepared based on the principles of “Focus on
                        Prevention, Aim at Self-rescue, Centralized Command, and Division of Responsibility”.
   Gutian Fuxing        The contingency plan was approved in May 2017 (File No. 352200-2017-005-L) and
                        amended in June 2020, and has passed expert review and completed filing (File No.
                        350922-2020-002-M).
                        According to the plan, the company conducted emergency drill for sudden hydrochloric
                        acid leakage in September 2022. After environmental emergencies occur, immediate,
                        quick, effective and orderly emergency rescue actions shall be taken to control and prevent

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Joincare Pharmaceutical Group                                                                Annual Report 2022


                         the spread of accident and contamination, and to protect the surrounding environment and
                         safeguard life and property of all employees, the company and nearby communities. In
                         accordance with the content and requirements of the plan, the company provides trainings
                         for its employees to get them well-prepared for environmental emergencies, so that timely
                         rescue can be taken and the accident can be controlled in a short period of time in case of
                         any environmental emergencies.
                         The principles of occupational health and safe environment administrative system were
                         followed, including occupational protection to ensure health, risk control to ensure safety,
                         prevention and control of pollution to protect the environment, and compliance with
                         discipline and law for continuous improvement. Identification of environmental factors
                         was performed seriously and preventive measures were adopted for significant
                         environmental factors, while the governance of the “Three Wastes” was strengthened to
                         enhance the ability of control over the “Three Wastes” and ensure that the discharge of the
                         “Three Wastes” had reached the discharge standards. The “Environmental Emergency
                         Contingency Plan of Livzon Group Limin Pharmaceutical Manufacturing Factory” (《丽
    Livzon Limin
                         珠集团利民制药厂突发环境事件应急预案》) was prepared in accordance with the
                         criteria of the environmental management system and the occupational health and safety
                         administrative system. The plan was issued in May 2021 (File No. 440203-2021-009-L).
                         According to the contingency plan, an environmental accident emergency drill was
                         conducted on 24 September 2021, and a specific drill summary was made. Identification
                         of environmental factors and sources of hazards and drills for emergency were conducted
                         internally in the company on a regular basis to improve the operability of the contingency
                         plan, and enhance the performance of the emergency rescue staff and the responsiveness
                         and coordination ability of the rescue team.
                         Pursuant to relevant provisions, the “Environmental Emergency Contingency Plan of
                         Livzon Group Livzon Pharmaceutical Factory” (《丽珠集团丽珠制药厂突发环境事件
                         应急预案》) was reformulated by the company in 2021, and has been approved, filed and
                         issued (File No. 440404-2021-0212-L). The company conducted a fire emergency
                         evacuation drill in the P10 workshop in April 2022 to improve employees’ emergency
Livzon Pharmaceutical    handling ability and to alleviate or eliminate the impact of the accident. On 21 October
       Factory           2022, the special emergency drill for alcohol leakage (causing fire and explosion) was
                         carried out to provide training to the emergency response team, thus enhancing the
                         emergency execution and disposal ability of the emergency drill participants, further
                         clarifing the responsibilities and tasks of relevant personnel, and improving the emergency
                         linkage mechanism. The company improved the awareness of risk prevention and the
                         ability of self-rescue and mutual-rescue.
                         The “Environmental Emergency Contingency Plan of Livzon Group (Ningxia)
                         Pharmaceutical Manufacturing Co., Ltd.” (《丽珠集团(宁夏)制药有限公司突发环境事
                         件应急预案》) was approved filed and issued in May 2019 (File No. 640221-2019-005-
                         II). Identification of environmental factors and sources of hazards and drills for emergency
Ningxia Pharmaceutical   were conducted internally in the company on a regular basis to improve the operability of
                         the contingency plan, and enhance the performance of the emergency rescue staff and the
                         responsiveness and comprehensive coordination ability of the rescue team. The
                         Environmental Emergency Contingency Plan was amended in May 2021, and has passed
                         expert review and the review by and the filing with government environmental department
                         in August 2021.
                         The “Environmental Emergency Contingency Plan of Jiaozuo Livzon Hecheng
                         Pharmaceutical Manufacturing Co., Ltd.” ( 《焦作丽珠合成制药有限公司突发环境事
                         件应急预案》) was prepared in accordance with the relevant provisions and requirements
                         and based on the principles of “prevention-oriented, on-alert all the time; classified
                         management, level-by-level response; cross-department cooperation, responsibility by
                         levels; scientific prevention and efficient handling”. The contingency plan was approved,
                         issued and filed in April 2021 (File No. 4108042018005L). The “Hazardous Waste
                         Environmental Pollution Emergency Contingency Plan of Jiaozuo Livzon Hecheng
                         Pharmaceutical Manufacturing Co., Ltd.” (《焦作丽珠合成制药有限公司危险废物环境
   Jiaozuo Hecheng       污染事故应急预案》) was prepared under the above provisions, requirements and
                         principles as well, which was approved and filed in January 2018. Identification of
                         environmental factors and sources of hazards and drills for emergency were conducted
                         internally in the company on a regular basis to improve the operability of the contingency
                         plan, and enhance the performance of the emergency rescue staff and the responsiveness
                         and coordination ability of the rescue team. The company carried out trainings on the
                         Standard Operating Procedure for Acid Mist Purification Towers and the Standard
                         Operating Procedure for Hazardous Waste Storage Pollutants in April 2021 and June 2021,
                         respectively. According to the relevant requirements of the Hazardous Waste
                         Environmental Pollution Emergency Contingency Plan of Jiaozuo Livzon Hecheng


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 Joincare Pharmaceutical Group                                                                Annual Report 2022


                         Pharmaceutical Manufacturing Co., Ltd. In November 2021, the “Operation Regulations
                         for Exhaust Gas UV Photolysis Equipment” was added and the “Spray Towers Operation
                         Regulations” was amended, and relevant trainings were conducted to increase the
                         environmental protection knowledge of staff. In March 2022, the company amended some
                         environmental protection documents, including the “Enterprise Environmental
                         Information Disclosure System”, “Discharge Permit System” and “Operating Procedures
                         for Sewage Treatment”.
                         In March 2022, the company issued and filed the “Environmental Emergency Contingency
                         Plan of Shanghai Livzon Pharmaceutical Manufacturing Co., Ltd.” (《上海丽珠制药有
    Shanghai Livzon      限公司突发环境事件应急预案》) (File No. 02-310115-2022-108-L). The company
                         conducts drills and reviews of the plan every year to improve its emergency response
                         capabilities through such regular trainings.
                         Pursuant to relevant provisions, the “Environmental Emergency Contingency Plan of
                         Livzon MAB” (《丽珠单抗突发环境事件应急预案》) was prepared by the company in
      Livzon MAB         2022. The company conducted an emergency response drill for hazardous chemical
                         leakage in the dangerous goods warehouse in June 2022 to improve employees’
                         emergency handling ability and alleviate or eliminate the impact of the accident.
                         The principles of occupational health and safe environment administrative system were
                         followed, including occupational protection to ensure health, risk control to ensure safety,
                         prevention and control of pollution to protect the environment, and compliance with
                         discipline and law for continuous improvement. Identification of environmental factors
                         was performed seriously and preventive measures were adopted for significant
                         environmental factors, while the governance of the “Three Wastes” was strengthened to
   Sichuan Guangda       enhance the ability of control over the “Three Wastes” and ensure that the discharge of the
                         “Three Wastes” had reached the discharge standards. The “Environmental Emergency
                         Contingency Plan of Livzon Group Limin Pharmaceutical Manufacturing Factory” (《(四
                         川光大製藥有限公司突发环境事件应急预案》 ) was prepared and issued on 23
                         December 2022. Identification of environmental factors and sources of hazards and drills
                         for emergency were conducted internally in the company on a regular basis.



 5. Environmental self-monitoring program
 √ Applicable □N/A

Name of company or
                                                  Environmental self-monitoring program
   subsidiary
                        As required by the self-monitoring program for pollutant discharge licenses, Jiaozuo Joincare
                        developed the 2022 self-monitoring program for wastewater and waste gas and carried out
                        self-monitoring according to the program. Up to the end of December, Jiaozuo Joincare has
                        completed the self-monitoring for wastewater and waste gas for the year of 2022.
  Jiaozuo Joincare
                        The company is a key enterprise in terms of soil monitoring, and should carry out self-
                        monitoring of soil once a year as required. In August 2022, the company has completed the
                        preparation, on-site sampling and review of self-monitoring program and published on the
                        website of the Group on 26 August 2022.
                        Wastewater was monitored once a quarter; boiler exhaust gas and plant boundary noise were
                        monitored once a year; exhaust gases generated from technical process was monitored once
Taitai Pharmaceutical
                        half a year; online monitoring facilities of wastewater and boiler exhaust gas were additionally
                        installed and functioning well.
                        A third party is entrusted to conduct regular monitoring strictly in compliance with the relevant
                        national laws and regulations and local requirements and ensure the accuracy, validity and
                        authenticity of the monitoring data. Online wastewater monitoring equipment was installed
   Haibin Pharma
                        and connected to environmental monitoring stations at municipal and district levels in
                        accordance with environmental monitoring technical standards. Data was promptly uploaded
                        on the national monitoring platform.
                        A self-monitoring program was prepared, the annual self-monitoring of exhaust gas,
  Xinxiang Haibin       wastewater and soil has been completed throughout the year in accordance with the pollutant
                        discharge license.
                        According to the relevant requirements of the “Measures for Self-Monitoring and Information
                        Disclosure by Enterprises subject to Intensive Monitoring and Control of the State (Trial
                        Implementation)” (《国家重点监控企业自行监测及信息公开办法 (试行)》) and the
   Fuzhou Fuxing        “Technical Guidelines for Self-Monitoring by Pollution Discharge Enterprises in the
                        Fermentation Pharmaceutical Industry (HJ882-2017)” (《排污单位自行监测技术指南发酵
                        类制药工业(HJ882-2017)》), the company has completed the establishment of the self-
                        monitoring program based on its own situation in a timely manner and made the program


                                                       112
Joincare Pharmaceutical Group                                                              Annual Report 2022


                       available to the public after being examined by and filed with Fuqing Environment Protection
                       Bureau and Fuzhou Environment Protection Bureau. The analysis methods of the monitoring
                       program comply with the national environmental monitoring technical standards and methods;
                       the monitoring and analysis instruments have been examined and calibrated in strict
                       compliance with the relevant national requirements; the automated monitoring equipment has
                       been installed in accordance with the requirements of environmental assessment technical
                       standards, connected to the network of competent environmental protection authorities and
                       passed the acceptance inspection conducted by the competent environmental protection
                       authorities. The automated monitoring equipment was sound, and the monitoring information
                       was accurate, valid and authentic. In June 2022, the volatile organic matters (VOCs) leak
                       detection and repair (LDAR) work in the first half of the year was finished. In November 2022,
                       the volatile organic matters (VOCs) leak detection and repair (LDAR) work in the second half
                       of the year was finished. Information publicity website: http://wryfb.fjemc.org.cn
                       According to the relevant requirements of the “Measures for Self-Monitoring and Information
                       Disclosure by Enterprises subject to Intensive Monitoring and Control of the State (Trial
                       Implementation)” (《国家重点监控企业自行监测及信息公开办法(试行)》), the company
                       has completed the establishment of the self-monitoring program based on its own situation in
                       a timely manner and made the program available to the public after being examined by and
                       filed with Qingyuan Environment Protection Bureau. The analysis methods of the monitoring
                       program comply with the national environmental monitoring technical standards and methods;
                       the monitoring and analysis instruments have been examined and calibrated in strict
                       compliance with the relevant national requirements. The automated monitoring equipment for
Livzon Xinbeijiang     wastewater (COD, ammonia nitrogen, pH, flow) and waste gas (non-methane hydrocarbons)
                       has been installed in accordance with the requirement of environmental assessment technical
                       standards, while online monitoring equipment has passed the inspection and acceptance of the
                       relevant environmental protection authorities and the connection between online information
                       and national development platform and Qingyuan municipal platform has been completed. The
                       automated monitoring equipment was sound, and the monitoring information was accurate,
                       valid and authentic. A third party is entrusted to conduct LDAR detection and repair every half
                       year in the workshop using VOCs in compliance with the specification requirements. The
                       fugitive volatile organic compounds around the workshop of the first refinery division were
                       monitored every half year, and the monitoring results met the standard in 2022.
                       Through self-monitoring, the requirements under the “Technical Standards for Application
                       and Issuance of Pollutant Discharge License for the Pharmaceutical Industry – Active
                       Pharmaceutical Ingredient Manufacturing (HJ858.1-2017)” (《排污许可证申请与核发技术
                       规 范 制 药 工 业 - 原 料 药 制 造 ( HJ858.1-2017 ) 》 ) were strictly implemented, and the
 Livzon Hecheng        verification and calibration of monitoring analyzing devices were carried out in strict
                       compliance with relevant provisions and connected with the national development platform as
                       required. In 2022, a third party was entrusted to carry out regular LDAR testing, emission port
                       testing, boundary noise monitoring and soil testing, and the test results were in line with the
                       requirements.
                       According to the relevant requirements of the “Measures for Self-Monitoring and Information
                       Disclosure by Enterprises subject to Intensive Monitoring and Control of the State (Trial
                       Implementation)” (《国家重点监控企业自行监测及信息公开办法(试行)》), the company
                       has completed the establishment of the self-monitoring program based on its own situation in
                       a timely manner and made the program available to the public after being examined by and
                       filed with Ningde Bureau of Ecology and Environment and Ningde Gutian Bureau of Ecology
                       and Environment. The analysis methods of the monitoring program comply with the national
                       environmental monitoring technical standards and methods; the monitoring and analysis
  Gutian Fuxing        instruments have been examined and calibrated in strict compliance with the relevant national
                       requirements; the automated monitoring equipment has been installed in accordance with the
                       requirements of environmental assessment technical standards, connected to the network of
                       competent environmental protection authorities and passed the acceptance inspection
                       conducted by the competent environmental protection authorities. The automated monitoring
                       equipment was sound, and the monitoring information was accurate, valid and authentic. In
                       June and December 2022, a qualified third party was engaged to complete volatile organic
                       matter leak detection and repair (LDAR) and a report was obtained. Information publicity
                       website: http://wryfb.fjemc.org.cn
                       An entity with national qualification on inspection was engaged to conduct monitoring strictly
                       in compliance with the relevant national laws and regulations and standards. In view of its own
                       specific conditions, the company appointed the inspection party to carry out water pollutant
                       detection monitoring every quarter, boiler exhaust gas monitoring every month and VOCs
  Livzon Limin
                       exhaust gas monitoring in R&D center every half year, with every monitoring strictly in
                       compliance with the relevant national requirements to ensure the accuracy, validity and
                       authenticity of the monitoring data. The inspection acceptance of the online monitoring
                       equipment for COD, ammonia nitrogen water quality was completed and it was put into use in


                                                     113
  Joincare Pharmaceutical Group                                                              Annual Report 2022


                         January 2021, and the equipment was monitored every 2 hours. The pollution source sharing
                         data were completed and filed to the Shaoguan Ecology and Environment Bureau on a timely
                         basis, and the relevant data were announced to the public after being reviewed by Shaoguan
                         Municipal Bureau Ecology and Environment.
                         An entity with national qualification on inspection was engaged to conduct monitoring strictly
                         in compliance with the relevant national laws and regulations and standards. In view of its own
                         specific conditions, the company appointed the inspection party to carry out monitoring on
Livzon Pharmaceutical
                         sewage and waste gas every month, with every monitoring strictly in compliance with the
       Factory
                         relevant national requirements to ensure the accuracy, validity and authenticity of the
                         monitoring data. The installation and commissioning of the online sewage monitoring
                         equipment was completed and it was put into use at the beginning of 2021.
                         The company formulated the self-monitoring program for 2022, which was reviewed by and
                         filed with the Ecology and Environment Bureau of Shizuishan City. Monthly and quarterly
                         monitoring was carried out strictly in accordance with the requirements of the program, which
                         focused primarily on organized exhaust gas emission, exhaust gas emission from boiler, waste
                         water discharge, underground water, soil, unorganized environmental air monitoring above
                         plant boundary, noise and recycled water TOC. The monitoring results would be announced
                         to the public through the “System of National Pollution Sources Monitoring Information
Ningxia Pharmaceutical   Management and Sharing Platform” (《全国污染源监测信息管理与共享平台系统》) and
                         the “System of Self-monitoring Information Open Platform for Enterprises in Shizuishan”
                         (《石嘴山市企业自行监测信息公开平台系统》). Volatile organic matter leak detection and
                         repair (LDAR) work was carried out. The automated monitoring equipment passed the
                         inspection conducted by the competent environmental protection authority and was connected
                         to the network of the competent environmental protection authority. The automated
                         monitoring equipment was sound, and the monitoring information was accurate, valid and
                         authentic.
                         According to the relevant requirements of the “Measures for Self-Monitoring and Information
                         Disclosure by the Enterprises subject to Intensive Monitoring and Control of the State (Trial
                         Implementation)” (《国家重点监控企业自行监测及信息公开办法(试行)》) , the company
                         implemented and completed the self-monitoring program based on its own specific conditions
                         in a timely manner and made the program available to the public after being examined by and
                         filed with relevant competent environmental protection authorities. The analysis methods of
                         the monitoring program comply with the national environmental monitoring technical
                         standards and methods; the monitoring and analysis instruments have been examined and
                         calibrated in strict compliance with the relevant national requirements. Volatile organic matter
   Jiaozuo Hecheng
                         leakage detection and repair (LDAR) was completed in June 2022. Equipment and facilities
                         such as solvent pipelines and flanges in the workshop were detected, and places with leakage
                         were repaired and rectified. The automated monitoring equipment for sewage has been
                         installed online in accordance with the requirement of environmental assessment technical
                         standards. The online monitoring equipment of COD, ammonia nitrogen, pH, flow and total
                         nitrogen was installed, which has been connected to the national development platform as
                         required. Monthly and quarterly monitoring was carried out strictly in accordance with the
                         requirements of the self-monitoring program, which focused primarily on organized exhaust
                         gas emission, waste water discharge, plant boundary unorganized environmental air and noise.
                         In accordance with the “General Rules for the Self-Monitoring Technical Guidelines for
                         Pollutant Discharge Units” (《排污单位自行监测技术指南总则》) (HJ819-2017) and the
                         relevant requirements (including those on pollution discharge license), the company organized
                         self-monitoring and information disclosure of the pollutants it has discharged, and formulated
   Shanghai Livzon
                         the Self-monitoring Program. In 2022, the company monitored main exhaust gas outlets once
                         a month, common discharge outlets once half year, noise once every quarter and sewage once
                         a month. The monitoring items and frequency meet the requirements of the pollutant discharge
                         license.
                         Entities with national qualification on inspection were engaged to conduct monitoring strictly
                         in compliance with the relevant national laws and regulations and standards. By considering
                         its own specific conditions, the Company appointed the inspection party to carry out regular
    Livzon MAB           monitoring on sewage and waste gas according to the requirements of the implementation plan
                         of the pollutant discharge permit, each time the monitoring would be conducted strictly in
                         compliance with the relevant national requirements to ensure the accuracy, validity and
                         authenticity of the monitoring data.
                         Entities with national qualification on inspection were engaged to conduct monitoring strictly
                         in compliance with the relevant national laws and regulations and standards. By considering
                         its own specific conditions, the Company appointed the third-party inspection party to carry
  Sichuan Guangda
                         out regular monitoring on sewage and waste gas according to the requirements of the
                         implementation plan of the pollutant discharge permit. COD water quality online monitoring
                         equipment was installed at the main sewage outlet of the company, which was monitored every



                                                       114
 Joincare Pharmaceutical Group                                                                  Annual Report 2022


                         2 hours, and the data were automatically uploaded to the platform of the government regulatory
                         department.


 6. Administrative penalties imposed for environmental issues during the Reporting Period
 □ Applicable √ N/A

 7. Other environmental information to be disclosed
 □ Applicable √ N/A

 (II) Statement on environmental protection measures of companies except for key pollutant
 discharge units
 √ Applicable □N/A
 The rest subsidiaries of the Company strictly implemented and obeyed the Environmental Protection
 Law of the People’s Republic of China, Cleaner Production Law of the People’s Republic of China
 and other environmental protection and safe production laws and regulations. They constantly
 increased investment in environmental protection, continuously invested in energy conservation and
 consumption reduction projects, actively promoted cleaner production, improved comprehensive
 utilization efficiency of resources, and reduced and avoided pollutants so as to ensure mental and
 physical health of employees and the coordinated and sustainable development of economic,
 environmental and social benefits.

 1. Administrative penalties imposed for environmental issues
 □ Applicable √ N/A

 2. Refer to other environmental information disclosed by key pollutant discharge units
 □ Applicable √ N/A

 3. Reason for non-disclosure of other relavant environmental information
 □ Applicable √ N/A

 (III) Relevant information contributing to ecological protection, pollution prevention and
 control, and fulfillment of environmental responsibilities
 √ Applicable □N/A

Name of company         Relevant information contributing to ecological protection, pollution prevention and
  or subsidiary                         control, and fulfillment of environmental responsibilities
 Jiaozuo Joincare    LDAR leak detection and repair was conducted twice in 2022.
                     Creation of environmental safety standardization, management of hazardous waste
                     standardization, onsite inspection, cooperation with the Department of Ecology and
     Taitai          Environment or its entrusted third-party evaluation agency to carry out the safety evaluation and
 Pharmaceutical      inspection of corporate environmental facilities, operating systems and online inspection
                     systems, prompt rectification of hidden hazards proposed were carried out as required by the
                     Municipal Department of Ecology and Environment.
                     The company completed LDAR detection in 2022, to timely repair leakage points and reduce
 Haibin Pharma       unorganized emission of VOCs. Laboratory exhaust gas treatment system was newly built to
                     reduce emission of VOCs.
                     The company completed LDAR detection in 2022, submit environmental protection
 Xinxiang Haibin     commitment to the management department and purchased environmental pollution liability
                     insurance for the company.
                     All waste water from production was collected and sent to the waste water treatment station for
 Joincare Haibin     treatment, and then sent back to the cooling tower for reuse, so as to realize“ zero” discharge of
                     waste water.
                     LDAR leak detection and repair was completed; the amendment and filing of the Environmental
 Fuzhou Fuxing       Emergency Contingency Plan was completed; preparation and inspection of “one policy for one
                     enterprise 2.0” was completed; the preparation of the “Environmental Impact Assessment Report


                                                        115
 Joincare Pharmaceutical Group                                                               Annual Report 2022


                     on the Phase IV High-end Antibiotics” was in process; in the environmental credit evaluation
                     completed, the company was rated as an environmentally credible enterprise. The monthly and
                     quarterly self-monitoring on waste water, waste gas and noise was completed as required. Self-
                     monitoring of soil and groundwater in 2022 was completed. The construction of 3000m3/d
                     sewage treatment facilities was completed. The installation of waste gas collection and treatment
                     pipeline between the sludge and bacterial residue plate and frame workshop was completed to
                     improve the air quality of the plate and frame workshop.
                     Two rounds of LDAR leak detection and repair was completed as required; unorganized
                     emission of VOCs was reduced; a series of exhaust gas and noise control and improvement
                     measures, such as connecting the exhaust gas fan of Workshop II of Refining I to the exhaust
                     gas treatment equipment, were made to reduce unorganized emission of VOCs; the old biological
                     deodorization tank in the sewage treatment station was replaced, and 2 new exhaust gas spray
                     towers were introduced; exhaust gas collection and treatment in the sewage treatment station
                     was upgraded; pollutants in exhaust gas were degraded efficiently; silencers were installed in
                     the sewage treatment station and on the exhaust gas vent of Fermentation II to reduce air-flow
Livzon Xinbeijiang
                     noise; fermentation II and the first floor of power freezer room were enclosed with brick wall to
                     diminish the impact of noise on the surrounding environment; 3 energy-saving silent cooling
                     towers newly purchased were installed on the south side of the freezer to reduce noise generation
                     and effectively use the freezer building to block noise transmission to the community. Other
                     equipment with much noise in the plant was enclosed with sound-absorbing cotton board to
                     reduce noise. The self-monitoring plan of the year was completed and the results of wastewater,
                     exhaust gas and noise met the emission standards. A qualified third party is entrusted to dispose
                     of the waste in compliance with laws and regulations.
                     LDAR leak detection and repair was completed in the year with a reduction of 1.11 tonnes as
                     compared with that befor repair; the equipment for RTO exhaust was maintained regularly to
                     ensure its safe operation and the emission of exhaust gas within the emission standards; items
                     were washed after the completion of RTO process to reduce sulfur dioxide emissions and smell;
                     the trichloromethane liquid nitrogen cryogenic equipment in Workshop 102 was put into use to
 Livzon Hecheng
                     increase the reuse of trichloromethane to reduce emissions. Qualified units were entrusted to
                     treat hazardous waste with a compliance treatment rate of 100%; and tail gas treatment facilities
                     were added at gas collection station by the QC Testing and Technical Development Department.
                     The self-monitoring program was completed and environmental responsibilities were fulfilled
                     as required.
                     LDAR leak detection and repair was completed; cover and sealing were added to sewage
                     treatment regulating pool; waste gas was collected and treated so as to avoid odor emit; HV
                     frame was replaced in the sewage treatment workshop; water content of sludge was reduced;
                     total volume of sludge was reduced; sludge generated was entrusted to qualified units for
                     treatment; the collection, recovery, treatment of VOCs were completed and online monitoring
  Gutian Fuxing
                     facilities was installed and put into operation to reduce the random emission of VOCs; and the
                     entrusted testing of waste water, waste gas, soil and groundwater in 2022 was completed, with
                     the results showing they all met standards. the upgrading and reconstruction of boiler tail gas
                     treatment facilities were completed. Hazardous waste was entrusted to qualified companies for
                     compliant treatment to reduce the risk of environmental pollution.
                     Pollutants was discharged according to the standards in the pollution discharge license and the
                     annual self-monitoring of pollution discharge was completed; the measures on energy
                     conservation and emission reduction were formulated according to ESG objectives; solid
                     preparations and steam equipment in high-capacity workshop were renovated; steam usage was
  Livzon Limin
                     reduced effectively; locations of different drugs in the overhead cabin and TCM cabin were
                     adjusted; storage energy consumption of the two cabins was reduced; three idle water pumps of
                     the factory were used; post-treated waste water was used for watering flowers, trees and grass
                     in the factory in three lines.
                     Installation and debugging of online monitoring equipment were completed; the monthly and
                     quarterly self-monitoring was completed as required; a qualified third party was entrusted to
                     detect waste water and waste gas; compliant treatment of hazardous wastes was made to reduce
    Livzon
                     the risk of environmental pollution. Environmental impact assessment was conducted for new
 Pharmaceutical
                     workshops and acceptance of environmental protection project of the newly-built workshop was
    Factory
                     completed as required. The facilities at the waste water treatment station were renovated to
                     ensure the sewage treatment meets the national standards, and at the same time, improve the
                     treatment efficiency.
                     In 2022, the exhaust sampling port and sampling platform of the hazardous waste storage and
                     waste gas collection and treatment facility was constructed; the fresh air supply facility of the
                     fungus residue crushing room was reconstructed, the original fresh air supply fan installed in
    Ningxia          the middle of the wall was moved to the bottom of the wall, and a new fresh air supply fan was
 Pharmaceutical      installed; the original waste gas treatment facilities of the fermentation workshop of 103-2 were
                     upgraded and improved, and a set of "sodium hypochlorite spray absorption + water spray
                     absorption + dual-phase superoxygen water + micro-nano bubbles" process governance facilities
                     were added; the emergency pool leakage prevention facilities of hazardous chemicals warehouse

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Joincare Pharmaceutical Group                                                                  Annual Report 2022


                    were built; the damaged cover plate of sludge storage tank was replaced;the cover plate of the
                    pre-aeration tank for sewage treatment and the water seal tank of the cover plate of the primary
                    sedimentation tank were repaired and sealed. The original cover plate for the pre-aeration tank
                    was sealed with glass fiber cloth and epoxy resin, and the rusted pipes were painted. The
                    rainwater and sewage collection pipe network facilities with a total length of about 1,000 meters
                    were laid and installed. In December 2022, it was recognized as a city-level green factory in
                    Shizuishan. The monthly and quarterly enterprise self-monitoring work was completed as
                    required.
                    Carried out automation construction; completed the repair and inspection of LDAR; completed
                    the green development evaluation of the pharmaceutical industry in Henan Province; replaced
                    the waste gas treatment part to ensure that the treatment effect of hazardous waste was entrusted
                    to a qualified unit for disposal, and the compliance disposal rate reached 100%; entrusted a
                    qualified third party to detect the waste gas; entrusted a qualified third party to provide operation
                    and maintenance services for wastewater system equipment; completed the implementation of
                    “one policy for one plant” for emergency emission reduction in heavily polluted weather by the
Jiaozuo Hecheng     Municipal Environmental Protection Bureau; the RTO incinerator equipment operated normally
                    this year, and modified the environmental protection documents such as “Enterprise
                    Environmental Information Disclosure System”, “Pollutant Discharge Permit System and
                    Sewage Treatment Process Operating Procedures”, “Enterprise Environmental Information
                    Disclosure System” 《企业环境信息公开制度》), the “Sewage Discharge Permit System” 《排
                    污许可证制度》) and the “Sewage Treatment Process Operation Regulations’ (《污水处理工
                    艺操作规程》).
                    The company has completed the Filing and Registration of the Contingenvy Plan for Emergenty
                    Environmental Incidents; completed the VOCs emission reduction milestone of " one plan for
                    one factory " in accordance with the plan; discharged pollutants in strict accordance with the the
                    Sewage Discharge Permit System obtained, formulated the annual emission self-monitoring
                    programme at the beginning of the year and implemented emission self-monitoring according to
                    the programme, and completed the annual implementation report of the emission permits without
Shanghai Livzon     any violations of laws or regulations. Meanwhile, we strengthened the daily supervision of the
                    operation of the waste gas treatment facilities and sewage treatment stations, and entrusted a
                    third party to test the emissions of waste gas and sewage every month to ensure the effective
                    operation of the equipment and facilities. The safety facilities, occupational disease protection
                    facilities and pollution prevention facilities of the "Preparation Line 3 and Assembly Line 2
                    Purification Plant and Utility System" project were designed, constructed and put into
                    production and use at the same time as the workshop renovation project.
                    Entrusted a qualified third party CTI to test the waste water and waste gas according to the
                    requirements of the pollutant discharge license, and entrusted a qualified entity, Dongjiang
                    Environmental-protection Doumen Yongxingsheng Environmental-protection, Co., Ltd. of
                    Dongjiang Environmental Protection (东江环保斗门永兴盛环保公司), to dispose of hazardous
                    wastes in accordance with the regulations, so as to reduce the risk of environmental pollution.
 Livzon MAB
                    Carried out the environmental impact assessment of the new workshop according to the
                    requirements of "Three Simultaneities" for construction of wotkshops newly built, rebuilt and
                    expanded. The production and R&D sewage was uniformly discharged into the sewage station
                    of Livzon Pharmaceutical Factory in Livzon Industrial Park for treatment and discharge up to
                    the standard.
                    According to the requirements, the company has formulated an annual self-monitoring plan for
                    sewage discharge, entrusted a qualified third party to carry out regular testing of waste water,
                    waste gas and noise at the factory boundary, and the testing results were all qualified; entrusted
                    a qualified unit to carry out compliance disposal of hazardous wastes to reduce the risk of
Sichuan Guangda     environmental pollution; completed the preparation and filing of the Contingency Plan for
                    Environmental Emergent Incidents of the Company; the environmental protection credit
                    evaluation has been completed, and the preliminary evaluation result was: the entity with good
                    environmental protection credit; the annual implementation report of pollutant discharge permit
                    has been completed.


 (IV) Measures Taken and Effects on Reducing Carbon Emissions During the Reporting
Period
 Whether to take carbon reduction measures                                          Yes
 Equivalent of carbon emission reduction (unit: ton)                              2,171
 Types of carbon emission reduction measures (e.g. Use of "clean energy for power
 use of clean energy for power generation, use of generation", adopt carbon emission
 carbon reduction technologies in production, reduction technologies in production" and
 research and development of new products that other measures, as detailed in "Specific
 contribute to carbon reduction, etc.)               descriptions" below.

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  Joincare Pharmaceutical Group                                                                  Annual Report 2022



  Specific descriptions
  √ Applicable □N/A

Name of company or
                         Measures taken and effects on reducing carbon emissions during the Reporting Period
   subsidiary
                        1. by upgrading the preheater of the No. 1 rectification tower in the solvent storage, saved about
                        2,000 tons of steam and reducing about 600 tons of carbon emissions annually;
                        2. by changing the structure of isopropyl alcohol distillation tower and the number of distillation,
  Jiaozuo Joincare
                        saved about 100 tons of steam annually, reduce carbon emissions about 30 tons;
                        3. by upgrading and replacing an air suspension aeration fan, saved 120,000 kWh of electricity
                        and reduce carbon emissions by about 60 tons per year.
                        1. in response to the call of the municipal government, the lighting in the park was replaced with
                        energy-saving lamps, obtaining remarkable power-saving effect;
                        2. in accordance with the energy-saving requirements of the municipal government, we
Taitai Pharmaceutical   organized to replace the high-power motor in the factory with a high-efficiency energy-saving
                        motor and installed a frequency conversion device to maximize energy saving;
                        3. upgraded 4T boilers with low nitrogen burners;
                        4. chose public transport for daily traffic, low-carbon travel, and turned off lights and machines.
                        Carried out carbon verification and energy saving diagnosis, sorted out key energy-use
   Haibin Pharma
                        equipment, and implemented targeted energy saving transformation to reduce carbon emissions.
                        1. by using diaphragm pump to replace centrifugal pump, saved 27,000 kWh of electricity per
                        year, reduced carbon emissions about 14 tons;
                        2. adding preheater for solvent recovery and using steam condensate to preheat mother liquor
                        raw materials can save about 3,600 tons of steam and reduce carbon emissions about 1,080 tons
  Xinxiang Haibin       per year;
                        3. the existing chemical pump was replaced by high efficiency and energy saving pump in the
                        circulating water system, which is expected to save 774,000 kWh of electricity and reduce
                        carbon emissions of about 387 tons per year;
                        4. chose public transport for daily traffic and low-carbon travel.
                        Purchased new standard energy-saving equipment, developed the habit and thinking of saving
                        electricity, saved natural gas and carried out multiple maintenance in daily use of boiler, and
  Joincare Haibin
                        frequemt;y inspected pipelines, took good insulation measures, and used pure electric cars to
                        save fuel when going out. Adopted solar water heater in the dormitory.
                        Used photovoltaic power generation to reduce power consumption; renovated high-
                        energyconsuming pumps for energy conservation to effectively reduce energy consumption;
                        replaced with high-efficiency motor water pumps to save energy consumption; vigorously
   Fuzhou Fuxing
                        promoted energy conservation and consumption reduction, and called on employees to realize
                        the concept of “turning off lights, air conditioners and computers before leaving office” during
                        their daily work.
                        Introduced photovoltaic power generation to reduce power consumption; used water kinetic
                        energy instead of electric motors to drive the cooling tower fans to reduce the electric energy
                        consumption while ensuring the cooling effect; pre-heated the soft water of the boiler by the heat
                        generated from the operation of the air compressor to raise the temperature of the inlet water of
                        the boiler and effectively reduce the consumption of natural gas; regularly cleaned the inner wall
 Livzon Xinbeijiang
                        of the MVR equipment to increase the evaporation rate of sugar water of the MVR equipment
                        by about 40%, hence effectively reducing the running time of the MVR equipment and greatly
                        reducing electricity onsumption; replaced old boilers of high energy consumption and high
                        maintenance cost with new boilers. Accordingly, the average natural gas consumption reduced
                        by 1.06 m3 per tonne of steam generated.
                        Maintained and updated chiller units to make more rational use of energy and saved electricity
                        consumption for production through more reasonable production scheduling by the production
                        department; used natural gas as fuel for canteens and boilers; replaced sewage treatment Roots
                        blowers in the environmental protection center with magnetic levitation blowers with an energy
  Livzon Hecheng        saving rate of about 30%, saving about 107,000 kWh of electricity consumption per year; called
                        on all employees of the factory to respond to electricity conservation, turn off lights and air
                        conditioners before leaving office, and limited the minimum temperature of air conditioners;
                        promoted green travel, encouraged the use of public transportation when going out to work, and
                        set up shuttle buses to transport employees to and from work.
                        Installed 4 air compressors with a capacity of 130m3/min to replace the original air compressor
                        with high power consumption to reduce power consumption; replaced one chiller unit to reduce
   Gutian Fuxing        electricity consumption; called on all employees to “save every drop of water, save every
                        kilowatt of electricity”, so that the lights are turned off and the equipment is powered off before
                        leaving office.
                        Appropriately adjusted the temperature and humidity settings of the air conditioning system
   Livzon Limin
                        (within the standard range) in the solid workshop to keep it as close to the outside temperature

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Joincare Pharmaceutical Group                                                                 Annual Report 2022


                     and humidity as possible, thus reducing steam consumption; reduced energy consumption by
                     controlling the number of running compressors in the air conditioning units and setting
                     parameters by the Quality Control Department, and by implementing intermittent use mode for
                     the bioassay lab; used hot tailwater from the water distiller in the production workshop to heat
                     the boiler soft water, thus reducing the consumption of natural gas; renovated the air
                     conditioning ventilation system at the R&D Centre to save electricity.
                     Reduced electricity consumption by replacing incandescent lamps with LED lamps; refurbished
                     photovoltaic inverter cabinets and roof-mounted photovoltaic modules, improving the
                     photovoltaic power generation efficiency after refurbishment, saving about 600,000 kWh of
   Livzon
                     electricity per year; introduced purchased steam to reduce boiler combustion and save energy;
Pharmaceutical
                     further strengthened the energy conservation management of functional departments, turned off
   Factory
                     lights during the lunch break, encouraged employees to turn off lights and computers to save
                     electricity before leaving seats or office; set up shuttle buses to transport employees to and from
                     work.
                     Renovated the phenylalanine concentration system and adopted MVR concentration to replace
                     the original triple-effect concentration system, thus reducing energy consumption by about 50%.
   Ningxia
                     Regularly overhauled and maintained the boiler system to ensure the efficient operation of the
Pharmaceutical
                     boiler body and the desulfurization and dust removal facilities. Increased the consumption of
                     steam from external supply to cut the use of coal and reduce carbon emissions.
                     Collected and reused steam condense to reduce steam consumption, so as to reduce carbon
                     emissions; changed the packaging equipment to automatic packaging to improve production
                     efficiency; vigorously promoted energy saving and consumption reduction internally, called on
                     all employees to “save every drop of water, save every kilowatt of electricity”, and uniformly
                     managed the paint in the workshop to eliminate waste; installed additional mirrors behind the
Jiaozuo Hecheng      steam pipeline drainage valves to observe whether there is steam loss; led the steam condense to
                     the production auxiliary system of the hot water tank and the crystallization tank to reduce the
                     use of steam; changed the lighting in the common areas of the workshop, corridors, etc. to sound-
                     or light-controlled switches and gradually replaced the workshop lighting with LED lights;
                     gradually replaced high energy consuming equipment and facilities in workshops with low
                     energy consuming or automated interlocking devices.
                     Further strengthened the daily energy-saving management according to the established energy-
                     saving plan, effectively improved the energy-saving awareness of employees through inspection,
                     publicity and other means, and cultivated good habit of saving water and electricity among
                     employees; optimized the peptide splicing process, increased the peptide splicing yield by more
Shanghai Livzon      than 10%, thus reducing the power consumption per unit of product; transformed the solid
                     preparation workshop into the powder injection workshop which produces less waste and
                     conserves electricity; while comfortable air conditioning unit (cooling) utilized the chilled water
                     unit in the power room, the multi-expansion air conditioning unit was placed outdoors to use air
                     cooling, saving cooling capacity and reducing energy consumption.
                     Introduced purchased steam to save energy. Effectively improved the energy-saving awareness
                     of employees through inspection, publicity and other means, and cultivated good habit of saving
 Livzon MAB          water and electricity among employees; used LED lights to reduce electricity consumption, and
                     encouraged employees to turn off lights and computers to save electricity before leaving office.
                     Set up shuttle buses to transport employees to and from work.
                     Clean energy was used, energy use efficiency was improved and outdated equipment was
                     eliminated. For example, Class 1 energy-efficient motors and related power products was used
Sichuan Guangda      for all new plant construction, and the highly efficient, energy-saving and low-cost MVR
                     concentration technology was used for concentration equipment. In addition, the energy-saving
                     awareness among staff is effectively raised by strengthening daily management.


II.Work on Corporate Social Responsibility
(I) Whether to disclose separate corporate social responsibility report, sustainable
development report or ESG report
√Applicable □N/A
The Company has separately disclosed its corporate social responsibility report. For details, please
refer to the 2022 Corporate Social Responsibility Report of Joincare Pharmaceutical Industry Group
Co., Ltd. disclosed by the Company on the website of Shanghai Stock Exchange (www.sse.com.cn)
on 11 April 2023 for details.

(II)Specific situation of work on corporate social responsibilities
√Applicable □N/A


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Joincare Pharmaceutical Group                                                                   Annual Report 2022


     External donation, public
                                             Quantity/content                          Description
              welfare
                                                                        Mainly include investment in public welfare
                                                                        projects for chronic diseases, industrial
 Total investment (RMB’0,000)                            1,211.7
                                                                        assistance, community health, and nature
                                                                        conservation.
                                                                        Mainly include investment in nature
 Including: Funds (RMB’0,000)                               569.9
                                                                        conservation project.
 Cash converted from materials                                          Mainly include investment in public welfare
                                                             641.8
 (RMB’0,000)                                                           projects for chronic diseases.
                                                                        Mainly include projects of low-income
 Number of beneficiary (person)                              1,485      chronic disease patients and industrial
                                                                        revitalization.

Specific description
√Applicable □N/A
The Company is striving to be an explorer in the healthcare industry and insisting on creating a
healthy life driven by technology. The Group pays great attention to its sustainable development,
and actively focuses on the internal regulatory environment and external policy guidance.
Considering China's 14th Five-Year Plan and the local government's development plan, the Group
has formulated a CSR strategy and goals adapting to its current business situation. Focusing
on“ health”, the Group's CSR strategy aims to provide the whole society with high-quality, safe,
accessible and affordable medical products and services through the development of its principal
businesses, while improving the overall strength of the health industry. Meanwhile, the strategy is
committed to empowering employees and communities, emphasizing environmental protection and
promoting the overall health development in society.
The development of enterprises relies on society. Over the years, the Company has conscientiously
fulfilled its social responsibility, paid taxes according to law, supported social public welfare
projects, and actively assumed its social responsibility for building a harmonious society. At the
same time, the Group was actively creating social value. It generated tax revenues for the
government of RMB1,668 million, paid RMB2,261million in salary to employees, distributed
dividends and paid interest worth RMB1,351 million to banks and other creditors, donated funds
and goods totaling RMB12.217 million to the society, and achieved a social contribution per share
of approximately RMB3.52 for the society in 2022.
For our performance of social responsibility, see the 2022 Corporate Social Responsibility Report
of Joincare Pharmaceutical Industry Group Co., Ltd. disclosed by the Company on the website of
Shanghai Stock Exchange (www.sse.com.cn) on 11 April 2023 for details.


III.Consolidation and expansion of achievements in poverty alleviation and rural
revitalization

 Targeted Poverty Alleviation and Rural
                                                   Quantity/content                       Description
 Revitalization Project
                                                                            Public welfare projects for chronic
 Total investment (RMB’0,000)                                       300
                                                                            diseases to help rural revitalization
 Including: Funds (RMB’0,000)
 Cash converted from materials (RMB’0,000)                          300    Donation of drugs for chronic diseases
                                                                            Low-income patients with chronic
 Number of beneficiary (person)                                  1,400
                                                                            diseases
 Forms of assistance (such as industrial
                                                  Poverty alleviation
 poverty alleviation, vocational poverty
                                                  through industrial
 alleviation, educational poverty alleviation,
                                                  development
 etc. )




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Joincare Pharmaceutical Group                                                      Annual Report 2022


Specific description
√Applicable □N/A

1. Industrial revitalization
The Company follows important guiding principles of the CPC Central Committee and the General
Secretary. In accordance with the relevant requirements, we establish and implement the plan of
“Revitalization of Astragalus Root (黄芪) Industry” and adopt the model of “Company + Base” and
“Company + Professional Cooperative”, encouraging locals to cultivate and process astragalus root
and develop the astragalus root industry based on the local conditions. Making it a pillar industry
for local economy in the long-term and a new path to improve the lives of the people, the Company
explores the development of the featured astragalus root industry to promote the construction of the
“Chinese Medicine Ecological Base”.
The “Revitalization of Astragalus Root Industry” program was initiated in 2017 and is still in
operation today. Datong Livzon Qiyuan Medicine Co., Ltd. (大同丽珠芪源药材有限公司 )
(“Datong Livzon”), a subsidiary of the Company’s controlled subsidiary Livzon Group, built
cultivation bases independently in Hunyuan County of Datong City in Shanxi Province and Zizhou
County of Yulin City in Shaanxi Province. And Datong Livzon cooperated with 12 cooperatives
and 3 individuals to jointly build cultivation bases for astragalus root in Tianzhen County of Datong
City and Ying County of Shuozhou City in Shanxi Province and Yulin City of Shaanxi Province.
The total area of the self-built bases and jointly constructed bases is about 33,000 mu and a total of
265 people have been assisted. This program has effectively boosted the economy of corresponding
areas in Shanxi and Shaanxi.
During the Reporting Period, the planting area of the self-built base in Hunyuan County of Datong
City in Shanxi Province increased by 300 mu, and the number of newly hired local workers reached
55. In addition, in line with the country's "rural revitalization strategy," Datong Livzon cooperated
with the village committee of Mazhuang Village, Guaner Township, Hunyuan County, Datong City,
Shanxi Province to initiate the “Joint Construction by Villages and Enterprises” program to
construct the initial processing plant for cultivation bases for astragalus root, which has been
completed and put into use. In addition, the Company provided training on the new version of "Good
Agricultural Practice of Medicinal Plants and Animals" for management staff of joint construction
bases and about 30 growers in Zizhou County, Yulin District, Shaanxi Province, and provided
technical guidance and practical training on the traceability system of Chinese medicinal materials.
At the same time, meteorological observation stations were set up in the joint-built base in Tianzhen
County of Datong City, Shanxi Province and the joint-built base in Zizhou County of Yulin City,
Shaanxi Province, and environmental inspection was carried out for all the joint-built bases,
providing data support for their field operations. This year, Shanxi and Shaanxi joint-built bases
employed 85 local workers, harvesting a total of 184.50 tons of fresh astragalus root.
2. Access to public welfare for rural revitalization chronic diseases prevention and treatment
In supporting consolidation and expansion of achievements in poverty alleviation and rural
revitalization and In order to respond positively to the call of national policy, Joincare have launched
“Access to Public Welfare for Chronic Diseases Prevention and Treatment (普惠慢病防治公益项
目)” program by combining our own industrial advantages. The program targets at common chronic
diseases such as hypertension, hyperlipidemia, cardiovascular and cerebrovascular diseases, and
treatment drugs have been donated to remote areas, including Pravastatin Capsules (普伐他汀钠胶
囊), Amlodipine Besylate Capsules (苯磺酸氨氯地平胶囊), Valsartan Capsules (缬沙坦胶囊),
and Isosorbide Bononitrate Tablets ( 单硝酸异山梨酯片), which could be worth millions of RMB.
These drugs can really help families in remote areas, make it convenient for patients in the regions

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Joincare Pharmaceutical Group                                                    Annual Report 2022


to take drugs nearby, help the families with patients to alleviate medical pressures, and provide
timely assistance. Based on actual conditions, the project regularly makes continuous drug
donations to remote areas and helps the families with patients in such regions. The project also helps
to promote local development of rural revitalization and contributes to the state strategic goal of
common prosperity.
Since late 2018 onwards, with the support of local government agencies and relevant authorities at
all levels, we carried out the “Inclusive Chronic Disease Prevention and Control Public Welfare
Project” successively in areas including Chaotian District of Guangyuan City, Songpan County,
Jiange County and Pingwu County of the Autonomous Prefecture of Aba Zangs and Qiangs in
Sichuan Province, Hunyuan County, Guangling County and Lingqiu County of Datong City in
Shanxi Province, Dongxiang County, Tianzhu County, Linze County and Shandan County in Gansu
Province, Xianghai national nature reserve in Jilin Province, Chayu County in Tibet Autonomous
Region, Macun District of Jiaozuo City in Henan Province, Huangshan District of Huangshan City
in Anhui Province, Suining County of Hunan Province, and Fenyi County of Jiangxi Province,
bringing benefits to many patients. Joincare won the awards of “19th Shenzhen Care Action Top
100 Projects of Residents Satisfaction (第十九届深圳关爱行动百佳市民满意项目)” and
“Pioneering Enterprise Award in Social Responsibility (社会责任先锋企业奖)” for its excellent
projects supporting urban revitalization.
As at 31 December 2022, the project covered 8 provinces and one autonomous region, among which
17 were remote areas in need of help and one was natural reserve at state level, which helped more
than 6,400 low-income patients. In 2023, it is expected to donate drugs to areas including Hubei,
Gansu, Anhui and Sichuan.




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     Joincare Pharmaceutical Group                                                                                                                                                                             Annual Report 2022




                                                                                                Chapter 6 Major Events
     I. Fulfillment of undertakings
       (I) Undertakings fulfilled during the Reporting Period or not yet fulfilled as of the Reporting Period by the parties to the commitment such as
     de facto controllers, shareholders, related parties, acquirers of the Company and the Company
                     √Applicable □N/A
                                                                                                                                                                                                       Specific          Next plan
                                                                                                                                                                   Whether
                                                                                                                                                                                    Whether           reasons for         should be
                                                                                                                                                Time and time      there is a
  Commitment             Commitment                                                           Commitment                                                                        commitment is          failure in     stated in case of
                                              Subject                                                                                              limit of       time limit
  background                type                                                                content                                                                         strictly fulfilled       timely           failure in
                                                                                                                                                 commitment           for
                                                                                                                                                                                     in time          fulfillment           timely
                                                                                                                                                                 fulfillment
                                                                                                                                                                                                     shall be given      fulfillment
                                                              Shenzhen Baiyeyuan Investment Co., Ltd., the controlling shareholder of the
                                                              Company, undertook that it would not be directly or indirectly engaged in or
                                                              cause subsidiaries and branches under its control to be engaged in any business
                         Settlement of                        or activity constituting horizontal competition with the Company after the
                                                                                                                                                30 April 2001,
                           horizontal       Baiyeyuan         founding of the Company, including but not limited to the research, production                         No               Yes                  -                 -
                                                                                                                                                long-term
                          competition                         and sales of any products that were the same as or similar to products under
                                                              research, production and sales of the Company, and was willing to undertake
                                                              compensation responsibility for economic losses to the Company arising from
                                                              violation of the said commitment.
                                                              Whereas the domestically listed foreign shares of Livzon Group, a controlled
                                                              subsidiary of the Company, sought listing on the Main Board of the Stock
                                                              Exchange of Hong Kong Limited, in order to fully ensure smooth completion
                                                              of the said event and in compliance with relevant requirements of the Stock
                                                              Exchange of Hong Kong Limited, the controlling shareholders, de facto
  Commitment                                                  controller of the Company and the Company entered into relevant undertakings
related to initial                                            with Livzon Group as follows: 1. The controlling shareholders, de facto
 public offering                                              controller and persons acting-in-concert of the Company, the Company and its
                                                              controlled subsidiaries except for Livzon Group did not or would not be,
                                           Baiyeyuan, de
                                                              directly or indirectly, engaged in any business that constituted competitive
                         Settlement of    facto controllers                                                                                     10 January
                                                              relation or potential competitive relation with drug research, development,
                            horizon         and persons                                                                                         2014, long-          No               Yes                  -                 -
                                                              production and sale businesses (“Restricted Businesses”) of Livzon Group
                          competition    acting-in concert,                                                                                     term
                                                              from time to time. For the avoidance of doubt, the scope of Restricted
                                         and the Company
                                                              Businesses did not cover products that were researched, developed,
                                                              manufactured and sold on the date of relevant letter of undertaking by the
                                                              controlling shareholders and de facto controller of the Company, the Company
                                                              and its controlled subsidiaries except for Livzon Group; 2. If any new business
                                                              opportunity was found to constitute competitive relation with Restricted
                                                              Businesses, the controlling shareholders, de facto controllers and persons
                                                              acting-in-concert of the Company, the Company and its controlling subsidiaries
                                                              except for Livzon Group would inform Livzon Group in written form
                                                              immediately and firstly provide Livzon Group with the business opportunity in

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                                accordance with reasonable and fair terms and conditions. If Livzon Group
                                gave up the business opportunity, the controlling shareholders and de facto
                                controllers of the Company, the Company and its controlled subsidiaries except
                                for Livzon Group may accept the business opportunity in accordance with the
                                terms and conditions that were not superior to those offered to Livzon Group;
                                3. If assets and businesses that directly or indirectly constituted competitive
                                relation and potential competitive relation with Restricted Businesses were
                                intended to be transferred, sold, leased, licensed to use or otherwise transferred
                                or allowed to use (these Sales and Transfers), the controlling shareholders and
                                de facto controllers of the Company, the Company and its controlled
                                subsidiaries except for Livzon Group would provide the right of first refusal for
                                Livzon Group under the same condition. If Livzon Group gave up the right of
                                first refusal, the controlling shareholders, de facto controllers and persons
                                acting-in-concert of the Company, the Company and its controlled subsidiaries
                                except for Livzon Group would carry out these Sales and Transfers to a third
                                party in accordance with main terms that were not superior to those offered to
                                Livzon Group; 4. The controlling shareholders, de facto controllers and persons
                                acting-in-concert of the Company, the Company and its controlled subsidiaries
                                except for Livzon Group would not be engaged in or involved in any business
                                that might damage the interests of Livzon Group and other shareholders
                                through the relation with shareholders of Livzon Group or the identity of
                                shareholders of Livzon Group; 5. The controlling shareholders, de facto
                                controllers and persons acting-in-concert of the Company, the Company and its
                                controlled subsidiaries except for Livzon Group would not or cause its contact
                                persons (except for Livzon Group) to directly or indirectly: (1) induce or
                                attempt to induce any director, senior management or consultant of any member
                                of Livzon Group to terminate his/her employment with or to be an employee or
                                consultant of Livzon Group at any time (whichever is applicable), no matter if
                                relevant acts of the person were against the Employment Contract or
                                Consultancy Agreement (if applicable); (2) Within three years after any person
                                terminated to be the director, senior management or consultant of any member
                                of Livzon Group, employ the person who had or might have any confidentiality
                                information or business secret in relation to Restricted Businesses (except for
                                the director, senior management or consultant of the Company and/or its
                                controlling subsidiaries except for Livzon Group on the date of issuance of
                                relevant letter of undertaking); (3) Recruit or lobby any person carrying out
                                business in any member of Livzon Group, accept orders, or carry out business
                                separately, through any other person or as any person, firm, or manager,
                                advisor, consultant, employee, agent or shareholder of any company
                                (competitor of any member of Livzon Group), or lobby or persuade the person
                                making transaction with Livzon Group or negotiating with Livzon Group on
                                Restricted Businesses to terminate its transaction with Livzon Group or reduce
                                its normal business volume with Livzon Group, or ask for more favorable
                                transaction terms to any member of Livzon Group. 6. The controlling
                                shareholders, de facto controllers and persons acting-in-concert of the
                                Company, the Company and its controlled subsidiaries except for Livzon Group
                                further undertook that: (1) They would allow and cause relevant contact persons
                                (except for Livzon Group) to allow independent directors of Livzon Group to
                                review if the Company and its controlled subsidiaries except for Livzon Group
                                obeyed the Letter of Undertaking at least once a year; (2) They would provide
                                all the data required for annual review and implementation of the Letter of

                                                                                          124
      Joincare Pharmaceutical Group                                                                                                                                     Annual Report 2022




                                                      Undertaking for independent directors of Livzon Group; (3) They would allow
                                                      Livzon Group to disclose the decision on whether the controlling shareholders
                                                      and de facto controllers of the Company, the Company and its controlled
                                                      subsidiaries except for Livzon Group obeyed and implemented the Letter of
                                                      Undertaking reviewed by independent directors of Livzon Group through the
                                                      annual report or announcement; (4) The controlling shareholders, de facto
                                                      controllers and persons acting-in-concert of the Company, the Company (and
                                                      its controlled subsidiaries except for Livzon Group) would provide Livzon
                                                      Group with the Letter of Confirmation in relation to compliance with clauses
                                                      of the Letter of Undertaking every year so as to be included in the annual report
                                                      of Livzon Group. 7. The controlling shareholders, de facto controllers and
                                                      persons acting-in-concert of the Company, and the Company undertake that
                                                      they would bear corresponding legal responsibility and consequence arising
                                                      from violation of any clause relevant letter of undertaking from the date of
                                                      issuance thereof by the Company (or the Company's controlled subsidiaries
                                                      except for Livzon Group or its contact persons). 8. The said undertakings would
                                                      terminate in case of the following circumstances (whichever is earlier): (1) The
                                                      controlling shareholders, de facto controllers and persons acting-in-concert of
                                                      the Company, the Company and any of its controlled subsidiaries were not
                                                      the controlling shareholders of Livzon Group anymore; (2) Livzon Group
                                                      terminated the listing of its shares on the Hong Kong Stock Exchange and other
                                                      overseas stock exchanges (except that shares of Livzon Group stopped to be
                                                      traded temporarily for any reason).
                                                                                                                                          From 8 March
                                                                                                                                          2016 to the
                                                                                                                                          date of
                                                                                                                                          completion of
                                      The Company                                                                                         remedial
                                                      Do not interfere in the operation and management activities of Livzon Group
                      Others           and de facto                                                                                       measures in       Yes   Yes   -             -
                                                      or encroach on the interests of Livzon Group
                                        controllers                                                                                       connection
                                                                                                                                          with the non-
                                                                                                                                          public offering
                                                                                                                                          of Livzon
                                                                                                                                          Group
                                                      Pursuant to the Guiding Opinions on Matters Relating to the Dilution of Current
   Commitment                                         Returns As a Result of Initial Public Offering, Refinancing and Major Asset
related to seasoned                                   Restructuring (Announcement of CSRC [2015] No. 31), the company shall
     offerings                                        undertake to adopt specific remedial measures relating to dilution of current       From 11 May
                                                      returns as a result of the company's initial public offering, refinancing of the    2017 to the
                                                      listed company, or major asset restructuring and shall fulfill such undertaking.    date of
                                                      Pursuant to relevant provisions of CSRC, Zhu Baoguo, the de facto controller        completion of
                                  Baiyeyuan and
                                                      of Shenzhen Baiyeyuan Investment Co., Ltd., a controlling shareholder:1. Do         remedial
                      Others       the de facto                                                                                                             Yes   Yes   -             -
                                                      not intervene in the operation and management activities or encroach on the         measures in
                                    controller
                                                      interests of the company; 2. If CSRC issued other new regulatory provisions on      connection
                                                      the remedial measures in relation to returns and the relevant undertakings and      with rights
                                                      the aforesaid undertakings did not conform to such provisions from the date of      issue of
                                                      issuance of the undertaking to the completion of IPO share allotment, the           Joincare
                                                      Company/the de facto controller would undertake to issue a supplemental
                                                      undertaking in accordance with the latest provisions of CSRC; 3. The
                                                      Company/the de facto controller undertook to practically take the remedial


                                                                                                               125
      Joincare Pharmaceutical Group                                                                                                                                        Annual Report 2022




                                                    measures in relation to returns formulated by the company and fulfill the
                                                    undertaking concerning the remedial measures. In case of violation of the
                                                    undertaking, causing losses to the company or investors, the Company/the de
                                                    facto controller was willing to assume compensation responsibilities to the
                                                    company or investors in accordance with law. In case of violation of the said
                                                    undertakings or rejection to fulfill the said undertakings, as one of the liability
                                                    subjects relating to the remedial measures concerning returns, it was agreed that
                                                    relevant punishment shall be imposed on or relevant management measures
                                                    shall be taken against the Company/the de facto controller by CSRC, the
                                                    Shanghai Stock Exchange and other securities regulators in accordance with
                                                    relevant provisions and rules set or issued by them.
                                                    After the proceeds for issuance of allotment were in place, the Company would
                                                    use them according to the disclosure in the announcement, and carry out the           From the date
                                                    policies, including deposit in special account, approval by specially-assigned        of proceeds
                                                    person, and special use of special funds in accordance with management                for issuance of
                                                    measures for proceeds of the Company. The Board of the Company would                  the Rights
                      Others          The Company   regularly check the progress of projects invested with proceeds, issue a special      issue in place    No   Yes   -               -
                                                    report on deposit and use of proceeds, engage an accounting firm during the           to the date of
                                                    annual audit to issue an verification report on deposit and use of proceeds,          completion of
                                                    would be supervised by regulators and sponsors at any time, and would not             use of
                                                    make major investment, asset purchase or similar financial investment though          proceeds
                                                    proceeds in disguise.
                                                    1. While transferring tradable shares subject to selling restrictions held by the
                                                    company in Livzon Group, the company shall strict obey relevant provisions of
Other commitments                                   Guidelines of Listed Companies on Transfer of Stock Shares Subject to
   made to the                                      Selling
Restrictions ([2008] No. 15); 2. If the Company had shares subject to         17 December
medium and small      Others          The Company   selling restrictions held by it in Livzon Group that were planned to be sold          2008, long-       No   Yes   -               -
shareholders of the                                 through the bid trading system of Shenzhen Stock Exchange and reduced more            term
     company                                        than 5% shares within six months from the first share reduction, the Company
                                                    would pass the
Announcement on Sales disclosed by Livzon Group within
                                                    two trading days before the first share reduction.




                                                                                                               126
Joincare Pharmaceutical Group                                                      Annual Report 2022



(II) If the Company has made profit forecast on its assets or projects and the Reporting Period is
still within the profit forecast period, the Company shall give an explanation on why its assets or
projects achieved its profit forecast
□Realized □Unrealized √N/A


(III) Fulfillment of performance covenant and its influence on goodwill impairment test
□Applicable √N/A



II. Information on Non-operating use of funds by controlling shareholders and other
related parties during the Reporting Period
□Applicable √N/A



III. Information on illegal guarantees
□Applicable √N/A


IV. The Board's statement on the “non-standard opinion auditor's report” issued by the
appointed accounting firm
□Applicable √N/A



V. Analysis and explanation from the Company on the reasons and impact of the change of
accounting policies, accounting estimates or correction on material accounting errors
 (I) Analysis and explanation from the Company on the reasons and impact of the change of
accounting policies or accounting estimates
□Applicable √N/A



(II) Analysis and explanation from the Company on the reasons and impact of the correction on
material accounting errors
□Applicable √N/A



(III) Communication with former appointed accounting firm
□Applicable √N/A



 (IV) Others
□Applicable √N/A




                                                 127
Joincare Pharmaceutical Group                                                                   Annual Report 2022



VI. Appointment and termination of appointment of accounting firm
                                                                                 Unit: 10,000 Yuan Currency: RMB

                                                                              Current accounting firm
 Name of domestic accounting firm                                          Grant Thornton (Special General Partnership)
 Remuneration for domestic accounting firm                                                                         128
 Continuous years of auditing services provided by domestic
                                                                                                                        4
 accounting firm
 Name of certified public accountant (“CPA”) of domestic
                                                                           Wang Yuan(王远) and Wang Qilai(王其来)
 accounting firm
 Continuous years of CPA audit services of domestic accounting
                                                                                                                1 and 4
 firms


                                                                    Name                                  Fee
   Accounting firm for internal control audit   Grant Thornton (Special General Partnership)                       32



Statement on appointment and termination of appointment of accounting firm

□Applicable √N/A


Statement on re-engagement of accounting firm during the audit period

□Applicable √N/A


VII. Risk of delisting
(1) Reasons for delisting risk warning

□Applicable √N/A


(2) Countermeasures to be taken by the Company
□Applicable √N/A


(3) Risk of delisting and the reasons
□Applicable √N/A



VIII. Matters related to bankruptcy and reorganization
□Applicable √N/A



IX. Material litigation and arbitration
□The Company was involved in material litigation or arbitration in current year

√The Company was not involved in material litigation or arbitration in current year

                                                        128
Joincare Pharmaceutical Group                                                                          Annual Report 2022



X. Violations committed by the listed company and its directors, supervisors, senior management,
controlling shareholders and de facto controllers, punishments imposed and rectifications
□Applicable √N/A


XI. Credit standing of the Company and its controlling shareholders and de facto controllers during
the Reporting Period
□Applicable √N/A


XII. Material related-party transactions
(I) Related-party transactions in connection with day-to-day operation
1. Matters already disclosed in interim announcements about which no new information is available
√Applicable □N/A
                               Overview                                                     Query index

   Pursuant to the “Resolution on Connected Transactions in the         See the “Announcement on Resolutions
   Ordinary Course of Business of the Majority-owned Subsidiaries        Considered and Approved at the 9th Meeting of
   of Jiaozuo Joincare and Jinguan Electric Power” considered and       the 8th Session of the Board of Joincare
   approved at the 9th Meeting of the 8th Session of the Board on 29     Pharmaceutical Group Industry Co., Ltd.” (Lin
   March 2022, Jiaozuo Joincare intended to purchase no more than        2022-026) and the “Announcement of Joincare
   RMB270 million (inclusive) of steam and power from Jinguan            Pharmaceutical Group Industry Co., Ltd. on the
   Electric Power in 2022 so as to satisfy the demands of Jiaozuo        Connected Transactions in the Ordinary Course of
   Joincare for steam and power in the process of production and         Business of the Majority-owned Subsidiaries of
   operation. The independent directors of the Company gave prior        Jiaozuo Joincare and Jinguan Electric Power” (Lin
   approval opinions on the Resolution and gave opinions on the          2022-032) disclosed by the Company on 31 March
   approval of the independent directors at the Board meeting.           2022 for details.


   The “Resolution on the Adjustment of Connected Transactions in
   the Ordinary Course of Business of the Majority-owned
   Subsidiary Jiaozuo Joincare and Jinguan Electric Power” was
   considered and approved at the 20th Meeting of the 8th Session of
   the Board on 12 December 2022: given that the actual power            See the “Announcement on Resolutions
   consumption of Jiaozuo Joincare was higher than forecast at the       Considered and Approved at the 20th Meeting of
   beginning of the year, the annual transaction amount estimated at     the 8th Session of the Board of Joincare
   the beginning of the year between Jiaozuo Joincare and Jinguan        Pharmaceutical Group Industry Co., Ltd.” (Lin
   Electric Power is not sufficient to cover Jiaozuo Joincare's actual   2022-141) and the “Announcement of Joincare
   production requirements in 2022, to satisfy the demands of Jiaozuo    Pharmaceutical Group Industry Co., Ltd. on the
   Joincare for steam and power in the process of production and         Adjustment of Connected Transactions in the
   operation, purchase from Jinguan Electric Power, was changed          Ordinary Course of Business of the Majority-
   from RMB270 million (inclusive) to RMB280 million (inclusive)         owned Subsidiaries of Jiaozuo Joincare and
   in 2022. The independent directors of the Company gave prior          Jinguan Electric Power” (Lin 2022-143) disclosed
   approval opinions on the Resolution and gave opinions on the          by the Company on 13 December 2022 for details.
   approval at the Board meeting.Both parties referred to the market
   price to fix a price of the said connected transactions.

   During the Reporting Period, the actual amount of the said
   connected transactions was RMB268.6670 million.


2. Matters already disclosed in interim announcements about which new information is available
□Applicable √N/A


                                                           129
 Joincare Pharmaceutical Group                                                                                   Annual Report 2022



 3. Matters not disclosed in interim announcements
 □Applicable √N/A

 (II) Related-party transactions involving acquisition or sale of assets or equity
 1. Matters already disclosed in interim announcements about which no new information is available
 □Applicable √N/A

 2. Matters already disclosed in interim announcements about which new information is available
 □Applicable √N/A

 3. Matters not disclosed in interim announcements
 □Applicable √N/A

 4. Fulfillment of performance covenants (if any) during the Reporting Period
 □Applicable √N/A

 (III) Material related-party transactions involving joint external investment
 1. Matters already disclosed in interim announcements about which no new information is available
 □Applicable √N/A

 2. Matters already disclosed in interim announcements about which new information is available
 □Applicable √N/A

 3. Matters not disclosed in interim announcements
 □Applicable √N/A

 (IV) Claims and debts with related parties
 1. Matters already disclosed in interim announcements about which no new information is available
 □Applicable √N/A

 2. Matters already disclosed in interim announcements about which new information is available
 □Applicable √N/A

 3. Matters not disclosed in interim announcements
 √Applicable □N/A
                                                                                                         Unit: Yuan Currency: RMB

                                                    Offer funds to related parties                 Receive funds from related parties

       Related party        Relationship                      Amount                                           Amount
                                            Opening                              Closing       Opening                          Closing
                                                           incurred in the                                  incurred in the
                                            balance                              balance       balance                          balance
                                                           current period                                   current period

Guangdong Blue Treasure
Pharmaceutical Co., Ltd.*     Others       25,653,956.55    -16,371,152.26      9,282,804.29   379,960.00       -379,960.00             0.00
(广东蓝宝制药有限公司)




                                                                130
 Joincare Pharmaceutical Group                                                                                            Annual Report 2022



Zhuhai Sanmed Gene
Diagnostics Ltd.* (珠海市圣          Others           229,288.83        -127,761.85       101,526.98
美基因检测科技有限公司)

Subsidiaries of Sichuan
Healthy Deer Hospital
Management Co., Ltd. (四川           Others           337,395.02         160,433.28       497,828.30      8,936.17         12,011.72        20,947.89
健康阿鹿医院管理有限公司
之子公司)

Zhuhai Sanmed Biotech Inc.*
(珠海圣美生物诊断技术有              Others           211,200.00                0.00      211,200.00
限公司)

Shenzhen Youbao
Technology Co., Ltd. (深圳           Others           154,500.00          33,600.00       188,100.00
市有宝科技有限公司)

Zhongshan Renhe Health
Product Co., Ltd. (中山市仁          Others           469,895.78                0.00      469,895.78
和保健品有限公司)

Shenzhen Jiekang Health
Care Co., Ltd.* (深圳市捷康          Others        18,577,246.63     -18,577,246.63             0.00
保健有限公司)

Shenzhen Health Deer
Technology Co., Ltd.(深圳
                                     Others              4,680.00               0.00        4,680.00
市健康阿鹿信息科技有限公
司)
Jiaozuo Jinguan Jiahua
Electric Power Co., Ltd. *         Associated
                                                    8,240,517.56      67,484,396.01 75,724,913.57
(焦作金冠嘉华电力有限公            company
司)
                       Total                       53,878,680.37      32,602,268.55 86,480,948.92       388,896.17       -367,948.28        20,947.89

                                                  During the Reporting Period, the Company had normal operating fund transactions with connected
Cause for claims and debts with related parties
                                                  parties.


Impact of claims and debts with related parties   The said credits and debts with connected persons are operating fund transactions; there was no non-
on the Company                                    operating use of funds of the Company by shareholders and connected part.




 (V) Financial business among the Company, related financial companies, financial companies
 controlled by the Company, and related parties
 □Applicable √N/A

 (VI) Others
 □Applicable √N/A


 XIII. Material contracts and their fulfilments
 (I) Trusteeship, contracting and lease
 1. Trusteeship
 □Applicable √N/A

 2. Contracting
 □Applicable √N/A


                                                                         131
        Joincare Pharmaceutical Group                                                                               Annual Report 2022



        3. Lease
        □Applicable √N/A

        (II) Guarantees
        √Applicable □N/A
                                                                                                         Unit: 10,000 Yuan Currency: RMB


                                               Date of
          Relation-ship
                                              guarantee                                                           Whether Guaranteed
           between the
                        Guaranteed Guaranteed (signing Effective Expiration Guarantee Fulfilled Overdue Overdue    there's a   for a
Guarantor guarantor and                                                                                                                  Relationship
                          party     amount     date of   date      date       type     or not or not    amount     counter-   related
            the listed
                                             agreement                                                            guarantee party or not
            company
                                                  )


            Headquarter   Jinguan                                                   Joint
 Joincare     of the      Electric   3,840.00 2022/2/14 2022/2/14 2022/11/30      liability   Yes   No    0         Yes         Yes        Assoiate
             Company       Power                                                 guarantee

            Headquarter   Jinguan                                                   Joint
 Joincare     of the      Electric   4,960.00 2022/2/24 2022/2/24 2022/12/26      liability   Yes   No    0         Yes         Yes        Assoiate
             Company       Power                                                 guarantee

            Headquarter   Jinguan                                                   Joint
 Joincare     of the      Electric   3,000.00 2022/6/8    2022/6/8   2023/6/8     liability   No    No    0         Yes         Yes        Assoiate
             Company       Power                                                 guarantee

            Headquarter   Jinguan                                                   Joint
 Joincare     of the      Electric   3,000.00 2022/6/22 2022/6/22 2023/6/23       liability   No    No    0         Yes         Yes        Assoiate
             Company       Power                                                 guarantee


            Headquarter   Jinguan                                                   Joint
 Joincare     of the      Electric   4,000.00 2022/7/11 2022/7/11 2023/7/11       liability   No    No    0         Yes         Yes        Assoiate
             Company       Power                                                 guarantee



            Headquarter   Jinguan                                                   Joint
 Joincare     of the      Electric   3,000.00 2022/7/11 2022/7/11 2023/7/11       liability   No    No    0         Yes         Yes        Assoiate
             Company       Power                                                 guarantee


            Headquarter   Jinguan                                                   Joint
 Joincare     of the      Electric   2,000.00 2022/7/15 2022/7/15 2023/7/15       liability   No    No    0         Yes         Yes        Assoiate
             Company       Power                                                 guarantee


            Headquarter   Jinguan                                                   Joint
 Joincare     of the      Electric   3,000.00 2022/8/8    2022/8/8   2023/8/8     liability   No    No    0         Yes         Yes        Assoiate
             Company       Power                                                 guarantee


            Headquarter   Jinguan                                                   Joint
 Joincare     of the      Electric   3,200.00 2022/9/16 2022/9/16 2023/9/16       liability   No    No    0         Yes         Yes        Assoiate
             Company       Power                                                 guarantee



            Headquarter   Jinguan                                                   Joint
 Joincare     of the      Electric   3,800.00 2022/10/9 2022/10/9 2023/10/9       liability   No    No    0         Yes         Yes        Assoiate
             Company       Power                                                 guarantee



            Headquarter   Jinguan                                                   Joint
 Joincare     of the      Electric   3,200.00 2022/10/12 2022/10/12 2023/10/12    liability   No    No    0         Yes         Yes        Assoiate
             Company       Power                                                 guarantee




                                                                           132
            Joincare Pharmaceutical Group                                                                                           Annual Report 2022



               Headquarter     Jinguan                                                      Joint
  Joincare       of the        Electric      3,000.00 2022/11/24 2022/11/24 2023/11/24    liability    No       No        0          Yes          Yes        Assoiate
                Company         Power                                                    guarantee


               Headquarter     Jinguan                                                      Joint
  Joincare       of the        Electric      4,640.00 2022/12/19 2022/12/19 2023/12/19    liability    No       No        0          Yes          Yes        Assoiate
                Company         Power                                                    guarantee


                 Wholly-       Jinguan                                                      Joint
  Jiaozuo
                  owned        Electric      2,000.00 2022/3/28 2022/3/28 2022/12/13      liability   Yes       No        0          Yes          Yes        Assoiate
  Joincare
                subsidiary      Power                                                    guarantee


                 Wholly-       Jinguan                                                      Joint
  Jiaozuo
                  owned        Electric      2,000.00 2022/12/14 2022/12/14 2023/12/14    liability    No       No        0          Yes          Yes        Assoiate
  Joincare
                subsidiary      Power                                                    guarantee

Total guaranteed amount occurred during the Reporting Period
                                                                                                                                                              48,640.00
(excluding guarantees to subsidiaries)

Total guaranteed amount as of the End of the Reporting Period (A)
                                                                                                                                                              37,840.00
(excluding guarantees to subsidiaries)

                                               Guarantee provided by the Company and its subsidiaries to subsidiaries

Total amount of guarantees to subsidiaries during the Reporting Period                                                                                       346,492.65

Total amount of guarantees to subsidiaries as of the End of the Reporting
                                                                                                                                                             250,888.69
Period (B)

                                          Total guaranteed amount of the Company (including guarantees to subsidiaries)
Total guaranteed amount (A+B)                                                                                                                                288,728.69

Percentage of total guaranteed amount in the Company's net assets (%)                                                                                             13.11

In which:

Amount of guarantees provided to shareholders, de facto controllers and
                                                                                                                                                                    0.00
their related parties (C)

Amount of debt guarantee directly or indirectly provided to a guaranteed
                                                                                                                                                             194,335.71
party with an asset-liability ratio exceeding 70% (D)

Portion of total guaranteed amount exceeding 50% of net assets (E)                                                                                                  0.00


Total guaranteed amount of the above three items (C+D+E)                                                                                                     194,335.71

Statement on the contingent joint liability that might be assumed in
                                                                                                                                                                    N/A
connection with outstanding guarantee
                                                                            The above connected guarantees are detailed in Note X 5(4) to the Financial Statements of
Statement on guarantees
                                                                            this report.



              (III) Entrusted cash asset management
            1. Entrusted wealth management
            (1) Overall situation of entrusted wealth management
            □Applicable √N/A

            Other information
            □Applicable √N/A

            (2) Single entrusted wealth management
            □Applicable √N/A


                                                                                    133
Joincare Pharmaceutical Group                                                       Annual Report 2022



Other information
□Applicable √N/A

(3) Provision for impairment of entrusted wealth management products
□Applicable √N/A

2. Entrusted loans
(1) Overall situation of entrusted loans
□Applicable √N/A

Other information
□Applicable √N/A

(2) Single entrusted loans
□Applicable √N/A

Other information
□Applicable √N/A

(3) Provision for impairment of entrusted loans
□Applicable √N/A

3. Other information
□Applicable √N/A

(IV) Other material contracts

□Applicable √N/A

XIV. Other significant matters having significant influence on the value judgment and decisions of
investors
√Applicable □N/A

1. Use of proceeds

Pursuant to the Reply to the Approval of Share Allotment of Joincare Pharmaceutical Group Industry Co.,
Ltd. issued by CSRC (Zheng Jian Xu Ke [2018] No. 1284), the Company allotted 365,105,066 shares to
original shareholders. The planned proceeds from the share allotment amounted to RMB2,000 million; the
total actual proceeds amounted to RMB1,715.9938 million; after deducting distribution expenses of
RMB46.2536 million, the net proceeds amounted to RMB1,669.7402 million. As at 16 October 2018, the
said proceeds were in place and validated by the Capital Verification Report of Joincare Pharmaceutical
Group Industry Co., Ltd. issued by Ruihua Certified Public Accountants (Rui Hua Yan Zi [2018] No.
40060006).




                                                  134
Joincare Pharmaceutical Group                                                           Annual Report 2022



(1) Temporary replenishment of working capital by use of proceed

Pursuant to the Resolution on the Temporary Replenishment of Working Capital with Idle Proceeds
considered and approved at the 7th Meeting of the 8th Session of the Board of the Company on 30
December 2021, it was agreed that the Company temporarily replenished the working capital with no more
than RMB700 million of idle proceeds from 1 January 2022 to 31 December 2022 so as to improve the use
efficiency of proceeds and reduce financial expenses of the Company. For details, please refer to the
Announcement on the Temporary Replenishment of Working Capital with Certain Idle Proceeds of Joincare
Pharmaceutical Group Industry Co., Ltd. (Lin 2021-159). On 21 December 2022, the Company returned
the temporary replenishment of working capital of RMB700 million to the special account, and the period
of use did not exceed 12 months.

Pursuant to the Resolution on the Temporary Replenishment of Working Capital with Idle Proceeds
considered and approved at the 21st Meeting of the 8th Session of the Board and the 18th Meeting of the 8th
Session of the Supervisory Committee of the Company on 29 December 2022, it was agreed that the
Company temporarily replenished the working capital with no more than RMB500 million of idle proceeds
from 1 January 2023 to 31 December 2023 so as to improve the use efficiency of proceeds and reduce
financial expenses of the Company. For details, please refer to the “Announcement on the Temporary
Replenishment of Working Capital with Certain Idle Proceeds of Joincare Pharmaceutical Group Industry
Co., Ltd.” (Lin 2022-146).

(2) Change of projects invested with proceeds

Pursuant to the Resolution on Change of Certain Projects Invested with Proceeds considered and approved
at the 8th Meeting of the 8th Session of the Board of the Company on 24 January 2022, it was agreed that
Zhuhai Health Industry Base Construction Project was changed to the New Product R&D Project, Haibin
Pharma Pingshan Pharmaceutical Industrialization Base Expansion Project and the Information Platform
Construction Project. The resolution was approved at the 2022 1st extraordinary general meeting of the
Company on 11 February 2022. For details of the aforesaid change of projects invested with proceeds, see
the “Announcement of Joincare Pharmaceutical Group Industry Co., Ltd. on Change of Certain Projects
Invested with Proceeds” (Lin 2022-007).

Meanwhile, based on the aforesaid change of projects invested with proceeds, the Company, Taitai
Pharmaceutical, a wholly-owned subsidiary of the Company, Haibin Pharma and Joincare Haibin,
together with Minsheng Securities Co., Ltd., signed the “Three-party Supervision Agreement for Deposit
into the Special Account for the Proceeds” 《募集资金专户存储三方监管协议》 with China Merchants
Bank Co., Ltd.     (Shenzhen Branch), Industrial Bank Co., Ltd. (Shenzhen Bagualing Sub-branch),
Industrial and Commercial Bank of China Limited (Shenzhen Hongwei Sub-branch) and China
Everbright Bank Co., Ltd. (University Town of Shenzhen Sub-branch), respectively. For details, please
refer to the “Announcement on the Signing of the Three-party Supervision Agreement for Deposit into
the Special Account for the Proceeds of Joincare Pharmaceutical Group Industry Co., Ltd.” (《健康元


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Joincare Pharmaceutical Group                                                           Annual Report 2022



药业集团股份有限公司关于签订募集资金专户存储三方监管协议的公告》) (Lin 2022-015).

For details about deposit and actual use of proceeds in 2022, please refer to the Special Report of Joincare
Pharmaceutical Group Industry Co., Ltd. on Deposit and Actual Use of Proceeds in 2022 disclosed by the
Company on 11 April 2023.

2. Matters about share repurchase

(1) First share repurchases in 2022

Pursuant to the Resolution on Share Repurchase Scheme by Way of Centralized Bidding Transactions and
other resolutions considered and approved at the 6th Meeting of the 8th Session of the Board and the 2021
Fifth Extraordinary General Meeting of the Company on 6 December 2021 and 23 December 2021, it was
approved that the Company repurchased company shares by way of centralized bidding transactions with its
own funds, and the repurchased shares will be used to reduce the registered capital; the total amount of
repurchase funds should be no less than RMB300 million (inclusive) and no more than RMB600 million
(inclusive); the repurchase price should be no more than RMB15/share (inclusive); the repurchase term
should be no more than 12 months from the date when the repurchase scheme was approved by the General
Meeting of the Company. For details, please refer to the “Announcement of Joincare Pharmaceutical Group
Industry Co., Ltd. on the Share Repurchase Scheme by Way of Centralized Bidding Transactions (Lin 2021-
145)” and the “Repurchase Report of Joincare Pharmaceutical Group Industry Co., Ltd. on Share Repurchase
by Way of Centralized Bidding Transactions” (Lin 2022-002).

On 7 July 2022, the Company completed the repurchase and has repurchased a total of 50,959,668 shares by
way of centralized bidding transactions, representing 2.66% of total share capital (1,912,540,667 shares) of
the Company. The highest purchase price was RMB13.02/share, the lowest, RMB10.02/share, and the
average, RMB11.77/share. The total amount paid was RMB599,981,715.83 (including handling fee), and
50,959,668 shares repurchased were cancelled on 11 July 2022. For details, please refer to the
“Announcement of Joincare Pharmaceutical Group Industry Co., Ltd. on Implementation Results of Share
Repurchase and Share Changes” (Lin 2022-076).

(2) Second share repurchases in 2022

Pursuant to the Resolution on Share Repurchase Scheme by Way of Centralized Bidding Transactions and
other resolutions considered and approved at the 17th Meeting of the 8th Session of the Board and the 2022
Fourth Extraordinary General Meeting of the Company on 14 October 2022 and 18 November 2021, it was
approved that the Company repurchased company shares by way of centralized bidding transactions with its
own funds, and the repurchased shares will be used to reduce the registered capital; the total amount of
repurchase funds should be no less than RMB300 million (inclusive) and no more than RMB600 million
(inclusive); the repurchase price should be no more than RMB16/share (inclusive); the repurchase term
should be from 18 November 2022 to 17 November 2023. For details, please refer to the “Announcement of
Joincare Pharmaceutical Group Industry Co., Ltd. on the Share Repurchase Scheme by Way of Centralized


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Joincare Pharmaceutical Group                                                               Annual Report 2022



Bidding Transactions” (Lin 2022- 121) and the “Repurchase Report of Joincare Pharmaceutical Group
Industry Co., Ltd. on Share Repurchase by Way of Centralized Bidding Transactions” (Lin 2022-137).

On 14 December 2022, the Company initially repurchased 348,400 shares by way of centralized bidding
transactions, representing 0.02% of the total share capital of the Company. For details, please refer to the
“Announcement of Joincare Pharmaceutical Group Industry Co., Ltd. on Initial Share Repurchase by Way
of Centralized Bidding Transactions” (Lin 2022-144).

As of 31 March 2023, the Company has repurchased a total number of 40,662,579 shares by way of
centralized bidding transactions, representing 2.11% of the total share capital (1,929,189,374) of the
Company. The total amount paid was RMB494.4911 million (including handling fee). For details, please
refer to the Announcement of Joincare Pharmaceutical Group Industry Co., Ltd. on the Progress of Share
Repurchase by Way of Centralized Bidding Transactions (Lin 2023-027).

3. GDRs of the Company was issued and listed on the SIX Swiss Exchange

Pursuant to the “Resolution on the Planning of Overseas Issuance of GDRs and Listing on the SIX Swiss
Exchange of the Company” (《关于公司筹划境外发行全球存托凭证并在瑞士证券交易所上市的议
案》) considered and approved at the 12th Meeting of the 8th Session of the Board of the Company on 15
June 2022. In order to broaden the Company’s international financing channels and enhance its
international brand and image, the Company intends to plan to issue Global Depositary Receipts (“GDRs”)
overseas and list on the SIX Swiss Exchange. For details, please refer to the “Reminder Announcement
of Joincare Pharmaceutical Group Industry Co., Ltd. on the Planning of Overseas Issuance of GDRs and
Listing on the SIX Swiss Exchange” (《健康元药业集团股份有限公司关于筹划境外发行全球存托凭
证并在瑞士证券交易所上市的提示性公告》) (Lin 2022-061).

Pursuant to the “Resolution on the Issuance of GDRs and Listing on the SIX Swiss Exchange and the
Conversion of the Company into a Company Limited by Shares that Issues and Lists Its Shares Abroad”
(《关于公司发行 GDR 并在瑞士证券交易所上市及转为境外募集股份有限公司的议案》), the
“Resolution on the Company’s Plan of the Issuance of GDRs and Listing on the SIX Swiss Exchange”
(《关于公司发行 GDR 并在瑞士证券交易所上市方案的议案》) and other relevant resolutions
considered and approved at the 13th Meeting of the 8th Session of the Board of the Company on 22 June
2022, the Company intends to issue GDRs representing newly issued RMB ordinary A Shares as underlying
securities. The additional underlying A Shares represented by the GDRs to be issued shall be no more than
191,254,066 Shares (including securities issued upon the exercise of any overallotment option, if any) and
shall not account for more than 10% of the Shares capital (1,912,540,667 Shares) of the Company prior to
the issuance. The number of the additional underlying A Shares represented by the GDRs to be issued shall
be adjusted according to relevant regulations if the share capital of the Company increases or decreases as
a result of bonus issue, capitalization issue or rights issue, share repurchase etc. during the period from the
date of approval of the issuance by the Board to the issuance date. The Company has simultaneously
formulated the “Confidentiality and Records Management System for Overseas Issuance of Securities and


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Joincare Pharmaceutical Group                                                          Annual Report 2022



Listing of Joincare Pharmaceutical Group Industry Co., Ltd.” (《健康元药业集团股份有限公司境外发
行证券与上市相关保密和档案管理工作制度》) and amended the “Articles of Association”, the “Rules
of Procedure for the Shareholders’ General Meetings” and other relevant company rules and regulations in
relation to GDRs. For details, please refer to the “Announcement on Resolutions Considered and Approved
at the 13th Meeting of the 8th Session of the Board of Joincare Pharmaceutical Group Industry Co., Ltd.”
( 《 健 康 元药 业 集团 股 份有 限 公 司八 届 董事 会 十三 次 会 议决 议 公告 》 ) (Lin 2022-063), the
“Confidentiality and Records Management System for Overseas Issuance of Securities and Listing of
Joincare Pharmaceutical Group Industry Co., Ltd.” (《健康元药业集团股份有限公司境外发行证券与
上市相关保密和档案管理工作制度》) and the “Announcement on the Formulation of the Articles of
Association and its Annexes Applicable to the Company upon the Listing of GDRs of Joincare
Pharmaceutical Group Industry Co., Ltd.” (《健康元药业集团股份有限公司关于制定公司 GDR 上市
后适用的《公司章程》及其附件的公告》(Lin 2022-064).

On 8 July 2022, the Company held the 2022 Second Extraordinary General Meeting to consider and approve
the aforesaid resolutions for the issuance of GDRs and listing in Switzerland and to request the general
meeting of the Company to authorize the Board and its authorized persons to deal with matters relating to
the issuance of GDRs and listing in full, as detailed in the “Announcement on Resolutions of Joincare
Pharmaceutical Group Industry Co., Ltd. at the 2022 Second Extraordinary General Meeting” (Lin 2022-
077).

On 19 August 2022, the Company obtained the conditional approval for the issuance and listing of GDRs
on the SIX Swiss Exchange from SIX Exchange Regulation AG, and the SIX Swiss Exchange Regulation
AG agreed to the listing of the Company’s GDRs on the SIX Swiss Exchange subject to the satisfaction of
customary conditions.

On 2 September 2022, the Company received the “Approval for the Initial Public Offering and Listing
of Global Depositary Receipts on the SIX Swiss Exchange by Joincare Pharmaceutical Group Industry
Co., Ltd.” (《关于核准健康元药业集团股份有限公司首次公开发行全球存托凭证并在瑞士证券交
易所上市的批复》) (Zheng Jian Xu Ke [2022] No. 1960) granted by the CSRC.

On 26 September 2022, the Company’s GDRs were listed on the SIX Swiss Exchange in an offering of
6,382,500 GDRs representing 63,825,000 underlying A shares, representing 3.31% of the Company’s total
share capital at that time, at an issue price of USD$14.42 per GDR, with the final gross proceeds of
approximately USD$92.04 million.

The lock-up restriction period for the redemption of the GDRs issued by the Company is from 26
September 2022 (Swiss time) to 23 January 2023 (Swiss time). As 23 January 2023 falls in the Chinese
New Year holiday, the transfer and settlement of A shares in relation to the cross-border conversion of
GDRs cannot proceed during the period from 23 January to 27 January 2023. In accordance with the
relevant regulations on stock connect, the GDRs with the expiry of the lock-up restriction period for the
redemption can be converted into A shares of the Company from 30 January 2023 (Beijing time). As of


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Joincare Pharmaceutical Group                                                          Annual Report 2022



the closing of the Shanghai Stock Exchange on 30 January 2023, the number of A shares of the Company
represented by the outstanding GDRs was less than 50% of the number of underlying A shares represented
by the GDRs actually issued by the Company as approved by the CSRC.

The proceeds from the Company’s issuance of GDRs, after deducting the issuance fees, are intended for
the business development and strategic investment of the Company, aimed at improving the Company's
capabilities of global research and development, industrialization and commercialization, thus further
deepening the international business presence and replenishing the working capital of the Company. As
of the end of this Reporting Period, the proceeds from the Company’s issuance of GDRs have not been
used.

4. Overall relocation and expansion project of Sichuan Guangda

On 6 March 2019, the board of directors of Livzon Group, the controlling subsidiary of the Company,
considered and approved that Livzon Group entered into the Investment Agreement for the “Overall
Relocation and Expansion Project of Sichuan Guangda Pharmaceutical Manufacturing” (《四川光大制药
整体搬迁调迁扩建项目投资协议书》) (the “Investment Agreement”) and the “Supplemental Agreement
I with Sichuan Chengdu Pengzhou Municipal People's Government” (四川省成都市彭州市人民政府).
Pursuant to the Investment Agreement, the Company will inject capital of RMB646 million for investment
in construction of the overall relocation and expansion project (the “Project”) of Sichuan Guangda, a
wholly-owned subsidiary of the Company. Pursuant to the Supplemental Agreement I, Pengzhou Municipal
People's Government has agreed to pay a compensation for demolition of RMB90 million and grant total
incentive of not more than RMB125.8 million for the construction of new plants to the Company.

As at 31 December 2022, the total investment of the Project under specific contracts amounted to
RMB542.2556 million, and subsidies received from governments at all levels totaled RMB138.9817 million.
After the QC decoration and renovation, equipment installation and warehousing system establishment, the
equipment was put into running for commissioning and the storage system was delivered for acceptance;
after the decoration, renovation and equipment installation of the extraction workshop and after the pre-
treatment workshop were completed, the equipment was put into running for commissioning and the
remaining work of local decoration was completed. The construction of the granulation workshop, the
integrated preparation workshop and the packaging workshop commenced, the remaining work of the
decoration and renovation of the alcohol extraction workshop was completed, and the pipeline equipment
had not installed for commissioning. The overall project went smoothly.

5. Progress of the initial public offering and listing of shares of Tianjin Tongrentang, a non-
controlling invested company

The Shenzhen Stock Exchange has suspended the review of listing of Tianjin Tongrentang on 26 January
2022, as CSRC has initiated an investigation against ShineWing Certified Public Accountants (Special
General Partnership), the audit institution engaged by Tianjin Tongrentang for the initial public offering
of its shares and listing on the ChiNext Board.

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Joincare Pharmaceutical Group                                                            Annual Report 2022



Considering that ShineWing Certified Public Accountants (Special General Partnership), the auditor
appointed by Tianjin Tongrentang, has issued a review report, the Shenzhen Stock Exchange has resumed
the review of the listing of Tianjin Tongrentang on 30 March 2022.

In addition to the above disclosure, details of the non-controlling invesmtnet in Tianjin Tongrentang are set
out in the Company’s annual report for 2021.

6. Progress of Livzon Group's plan to spin off Livzon Diagnostics for A-share listing

On 7 August 2020, the board of directors of Livzon Group, a majority-controlled subsidiary of the Company,
considered and approved the proposal to spin off its subsidiary Zhuhai Livzon Diagnostics Inc. for A-share
listing (hereinafter referred to as spin-off listing). Livzon Diagnostics is mainly engaged in the R&D,
production and sale of diagnostic reagents and equipment. As at the End of the Reporting Period, Livzon
Group held approximately 39.425% of shares of Livzon Diagnostics. After completion of this spin-off, the
shareholding structure of Livzon Group will remain unchanged, and Livzon Group will still maintain control
over Livzon Diagnostics. For details, see the “Suggestive Announcement of Joincare Pharmaceutical Group
Industry Co., Ltd. on Livzon Group's Planned Spin-off of Its Subsidiary Livzon Diagnostics for A-share
Listing” (Lin 2020-106).

On 16 October 2020, the Stock Exchange of Hong Kong Limited agreed to Livzon Group's spin-off listing,
and agreed to exempt the group from the applicable regulations concerning the assured entitlement related
to the spin-off listing. For details, see the “Announcement of Joincare Pharmaceutical Group Industry Co.,
Ltd. on the Progress of Livzon Group's Planned Spin-off of Its Subsidiary Livzon Diagnostics for A-share
Listing” (Lin 2020-131).

Livzon Diagnostics would go spin-off listing on the ChiNext Board of Shenzhen Stock Exchange pursuant
to the Resolution on the Spin-off of the Subsidiary Zhuhai Livzon Diagnostics Inc. to Go Listing on the
ChiNext Board of Shenzhen Stock Exchange considered and approved at the board meeting of Livzon
Group on 23 October 2020. For details, see the “Announcement of Joincare Pharmaceutical Group Industry
Co., Ltd. on the Progress of Livzon Group's Planned Spin-off of Its Subsidiary Livzon Diagnostics for A-
share Listing” (Lin 2020-134).

The spin-off listing of Livzon Diagnostics was approved at the 2020 4th extraordinary general meeting of
Livzon Group on 20 November 2020, and was registered with Guangdong Securities Regulatory Bureau
for pre-listing tutoring in November 2020. As of the disclosure date of this report, Livzon Diagnostics has
submitted the nine issues of reports on progress of the tutoring. As of the disclosure date of this report,
Livzon Diagnostics has not submitted any application to or registered with Shenzhen Stock Exchange or
any relevant Chinese regulatory authorities other than those progresses listed above.




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          Joincare Pharmaceutical Group                                                                                         Annual Report 2022




                                  Chapter 7 Changes in Equity and Shareholders


          I. Changes in Share Capital
          (I) Table of changes in shares
          1. Table of changes in shares
                                                                                                                                             Unit: shares
                        Before the current change                   Increase/decrease (+, -) due to the current change                   After the current change
                                                                                     Conversion
                                                                       Issuance
                                        Percentage      Issuance of                   of capital                                                        Percentage
                         Number                                        of bonus                           Others         Subtotal         Number
                                           (%)          new shares                    reserve to                                                           (%)
                                                                         shares
                                                                                    share capital
I. Shares subject to
                                  0                 0             0             0                0               0                  0              0                0
selling restrictions
1. Shares held by
state government
2. Shares held by
state-owned
entities
3. Shares held by
other domestic
holders
Of which: Shares
held by domestic
non-state-owned
entities
         Shares held
by domestic
natural persons
4. Shares held by
foreign holders
Including: Shares
held by foreign
entities
         Shares held
by foreign natural
persons
II. Shares without
                       1,907,727,908           100      72,421,134              0                0    -50,959,668        21,461,466     1,929,189,374          100
selling restrictions
1. Ordinary shares
denominated in         1,907,727,908           100      72,421,134              0                0    -50,959,668        21,461,466     1,929,189,374          100
Renminbi
2. Domestically
listed foreign
shares
3. Overseas listed
foreign shares
4. Others
III. Total number
                       1,907,727,908           100      72,421,134              0                0    -50,959,668        21,461,466     1,929,189,374          100
of shares



          2.Explanations on changes in shares

          √Applicable □N/A

          (1) Share repurchase for cancellation

          From 24 December 2021 to 23 December 2022, the Company expected to repurchase shares at a price of
          no more than RMB15 per share (inclusive) and the total amount of repurchase funds shall be not less than

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Joincare Pharmaceutical Group                                                        Annual Report 2022



RMB300 million (inclusive) and not more than RMB600 million (inclusive). The repurchased shares will
be used to reduce the Company's registered capital. The Company has repurchased a total of 50,959,668
shares as of 7 July 2022, and cancelled such shares with the Shanghai Branch of China Securities
Depository and Clearing Corporation Limited on 11 July 2022.

(2) Issuance of GDRs

The Company held the 2022 second extraordinary general meeting on 8 July 2022, at which it reviewed
and approved the Resolution on the Company’s Issuance of GDRs, Listing on the SIX Swiss Exchange
and Conversion into a Joint Stock Limited Company Offering Shares Overseas (《关于公司发行 GDR
并在瑞士证券交易所上市及转为境外募集股份有限公司的议案》) and other relevant resolutions.
6,382,500 GDRs were issued by the Company, representing 63,825,000 underlying A shares, with one
GDR represents 10 A Shares of the Company, and were listed on the SIX Swiss Exchange on 26 September
2022. The total share capital of the Company increased by 63,825,000 shares as a result of the issuance
and listing of the GDRs mentioned above.

(3) Exercise of the 2018 share options

The third exercise period for the options first granted under the Company's 2018 Share Options Incentive
Plan commenced on 21 December 2021, namely from 21 December 2021 to 20 December 2022. The
second exercise period for the reserve options commenced on 23 September 2021, namely from 23
September 2021 to 22 September 2022. During the Reporting Period, the cumulative number of share
options exercised and completing share transfer registration was 8,596,134.


3.The influence of changes in shares on financial indicators such as earnings per share and net assets
per share in the most recent year and the most recent Reporting Period (if applicable)
□Applicable √N/A

4.Other information disclosed as the Company deems necessary or required by the securities
regulatory authority
□Applicable √N/A

(II) Changes in shares subject to selling restrictions
□Applicable √N/A

II. Issuance and Listing of Securities
(I) Securities issued during the Reporting Period
□Applicable √N/A

Explanations on securities issuance during the Reporting Period (list separately bonds with different
interest rates during the duration):
□Applicable √N/A

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         Joincare Pharmaceutical Group                                                                          Annual Report 2022



         (II) Changes in total number of shares, shareholding structure, and structure of assets and liabilities
         of the Company
         □Applicable √N/A


         (III) Outstanding shares granted under the employee share ownership scheme
         □Applicable √N/A


         III. Information on Shareholders and the De Facto Controller
         (I) Total number of shareholders
           Total number of shareholders of ordinary shares as of the End of the
                                                                                                                               93,510
           Reporting Period
           Total number of shareholders of ordinary shares as of the end of the
                                                                                                                               87,173
           month immediately prior to the publish date of this annual report


         (II) Shares held by top 10 shareholders and top 10 holders of tradable shares (or shares without
         selling restrictions) as of the End of the Reporting Period
                                                                                                                             Unit: shares
                                                     Shareholdings of the Top 10 shareholders
                                                                                  Number of        Pledge, mark or lock-up
                                   Change          Number of                         shares
  Name of shareholder (Full       during the     shares held at    Percentage         held                                              Nature of
           name)                  Reporting      the end of the       (%)          subject to    Share status         Number           shareholder
                                   Period            Period                         selling
                                                                                  restrictions
Shenzhen Baiyeyuan                                                                                                                    Domestic
Investment Co., Ltd.* (深圳市     -17,380,900      878,272,753           45.53              0      Pledge             95,679,725      non-state-
百业源投资有限公司)                                                                                                                   owned entity
Hong Kong Securities Clearing
                                   21,294,741      113,256,167            5.87              0     Unknown                             Unknown
Company Limited
                                                                                                                                      Foreign
Citibank, National Association     63,825,000       63,825,000            3.31              0     Unknown
                                                                                                                                      entity
                                                                                                                                      Foreign
Might Seasons Limited             -14,371,900       57,487,434            2.98              0     Unknown
                                                                                                                                      entity
Huaxia Life Insurance Co., Ltd.
                                      163,100         9,275,718           0.48              0     Unknown                             Unknown
- Equity fund
Agricultural Bank of China
Limited - CSI 500 Exchange
                                    2,663,000         8,060,294           0.42              0     Unknown                             Unknown
Traded Index Securities
Investment Fund
                                                                                                                                      Domestic
He Zhong                              -50,000         7,800,024           0.40              0     Unknown                             natural
                                                                                                                                      person
Joincare Pharmaceutical Group
Industry Co., Ltd. — the
Second Phase Ownership
                                    6,275,372         6,275,372           0.33              0     Unknown                             Others
Scheme under Medium to
Long-term Business Partner
Share Ownership Scheme
Abu Dhabi Investment                                                                                                                  Foreign
                                    4,808,605         5,920,342           0.31              0     Unknown
Authority                                                                                                                             entity

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         Joincare Pharmaceutical Group                                                                                   Annual Report 2022



Bosera Funds Management
Co., Ltd. - 419 portfolio of          -3,696,377          5,036,569            0.26             0         Unknown                             Unknown
social security funds
                                           Shareholdings of the Top 10 shareholders without selling restrictions
                                                    Number of tradable shares held                          Class and number of shares
              Name of shareholder
                                                     without selling restrictions                          Class                              Number
Shenzhen Baiyeyuan Investment Co., Ltd.* (深圳
                                                                      878,272,753       Ordinary shares denominated in Renminbi                878,272,753
市百业源投资有限公司)
Hong Kong Securities Clearing Company Limited                          113,256,167      Ordinary shares denominated in Renminbi                113,256,167
Citibank, National Association                                           63,825,000     Ordinary shares denominated in Renminbi                 63,825,000
Might Seasons Limited                                                    57,487,434     Ordinary shares denominated in Renminbi                 57,487,434
Huaxia Life Insurance Co., Ltd. - Equity fund                             9,275,718     Ordinary shares denominated in Renminbi                   9,275,718
Agricultural Bank of China Limited - CSI 500
Exchange Traded Index Securities Investment                               8,060,294     Ordinary shares denominated in Renminbi                   8,060,294
Fund
He Zhong                                                                  7,800,024     Ordinary shares denominated in Renminbi                   7,800,024
Joincare Pharmaceutical Group Industry Co., Ltd.
— the Second Phase Ownership Scheme under
                                                                          6,275,372     Ordinary shares denominated in Renminbi                   6,275,372
Medium to Long-term Business Partner Share
Ownership Scheme
Abu Dhabi Investment Authority                                            5,920,342     Ordinary shares denominated in Renminbi                   5,920,342
Bosera Funds Management Co., Ltd. - 419
                                                                          5,036,569     Ordinary shares denominated in Renminbi                   5,036,569
portfolio of social security funds
                                                         As at the End of the Reporting Period, the special repurchase account of the Company (special
Notes on the special repurchase account among
                                                    securities repurchase account of Joincare Pharmaceutical Group Industry Co., Ltd.) owned 28,417,048
the Top 10 shareholders
                                                    shares in total, accounting for 1.47%.
Description of the above shareholders involved in
entrustment/entrusted voting right and waiver of        Not applicable
voting right
                                                         There was no connection or acting-in-concert relationship between Shenzhen Baiyeyuan Investment
Description of connection or acting-in-concert
                                                    Co., Ltd., a controlling shareholder of the Company, and other shareholders; whether there is connection
relationship of the above shareholders
                                                    or acting-in-concert relationship among other shareholders is unknown.

         Notes: 1. As of the End of the Reporting Period, the balance of shares lent by Shenzhen Baiyeyuan Investment Co., Ltd. *
         (深圳市百业源投资有限公司), a controlling shareholder of the Company, by participating in the refinancing business was
         17,380,900, and the ownership transfer of such shares does not take place.

         2. Citibank, National Association is the depositary for GDRs of the Company, and the underlying domestic A shares
         represented by the GDRs are registered in its name according to law. The GDRs issued by the Company may not be
         converted into A shares from 26 September 2022 (Swiss time) to 23 January 2023 (Swiss time).


         Number of shares held by the Top 10 shareholders with selling restrictions and the description of
         the selling restrictions
         □Applicable √N/A


         (III) Strategic investors or general legal persons who became top 10 shareholders as a result of
         allotment of new shares
         □Applicable √N/A




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Joincare Pharmaceutical Group                                                                      Annual Report 2022



IV. Information on the Controlling Shareholder and the De Facto Controller
(I) Information on the Controlling shareholder
1. Legal person
√Applicable □N/A
 Name                                     Shenzhen Baiyeyuan Investment Co., Ltd.* (深圳市百业源投资有限公司)
 Person in charge of the unit or legal
                                          Zhu Baoguo
 representative
 Date of incorporation                    21 January 1999
                                          Investment in industry, domestic commerce, and material supply and
 Principal business
                                          marketing industry
 Equity held in other domestic and        Except for the daily trading of securities assets in the secondary market,
 overseas listed companies during the     Baiyeyuan did not hold or participate in the equity of other domestic and
 Reporting Period                         overseas listed companies during the Reporting Period.
 Others                                   Not applicable


2.Natural person
□Applicable √N/A

3.Special statement if the Company does not have a controlling shareholder
□Applicable √N/A

4.Statement on changes in controlling shareholders during the Reporting Period
□Applicable √N/A

5.Block diagram describing controlling shareholders' ownership of and control over the Company
√Applicable □N/A




Note: As of the End of the Reporting Period, the balance of shares lent by Shenzhen Baiyeyuan Investment Co., Ltd. * (深
圳市百业源投资有限公司), a controlling shareholder of the Company, by participating in the refinancing business was
17,380,900, and the ownership transfer of such shares does not take place.


(II) Information on the de facto controller
1.Legal person
□Applicable √N/A


                                                            145
Joincare Pharmaceutical Group                                                                     Annual Report 2022



2.Natural person
√Applicable □N/A
 Name                                                                        Zhu Baoguo
 Nationality                                                                   China
 Hold the right of residence in other countries
                                                                                 No
 or regions or not
 Main occupation and position                                 Chairman of the Company and Livzon Group
 Domestic and overseas listed companies           Except for the Company and Livzon Group, Mr. Zhu Baoguo has never
 controlled in the past 10 years                  controlled any other domestic and overseas listed companies


3.Special statement if the Company does not have a de facto controller
□Applicable √N/A


4.Statement on change of control of the Company during the Reporting Period
□Applicable √N/A


5.Block diagram describing de facto controllers' ownership of and control over the Company
√Applicable □N/A




Note: As of the End of the Reporting Period, the balance of shares lent by Shenzhen Baiyeyuan Investment Co., Ltd. * (深
圳市百业源投资有限公司), a controlling shareholder of the Company, by participating in the refinancing business was
17,380,900, and the ownership transfer of such shares does not take place.


6.De facto controller controls the Company through trust or other asset management methods
□Applicable √N/A


(III) Other information on the controlling shareholder and the de facto controllers
□Applicable √N/A


V. Cumulative Number of Shares Pledged by Controlling Shareholders or the Largest Shareholder
of the Company and Their Persons Acting in Concert Accounts for More Than 80% of the Shares
Held by Them in the Company
□Applicable √N/A



                                                           146
Joincare Pharmaceutical Group                                                                      Annual Report 2022



VI. Other Corporate Shareholders Holding More Than 10% Shares
□Applicable √N/A


VII. Explanation on Restrictions on Share Selling
□Applicable √N/A


VIII. Information on Implementation of Share Repurchases Plans during the Reporting Period
√Applicable □N/A
                                                                                          Unit: 10,000 Yuan Currency: RMB
          Name of share repurchase plan                        Plan on share repurchase by centralized bidding
 Disclosure date of share repurchase plan                7 December 2021
 Number of shares to be repurchased and its
                                                         1.05~2.10
 percentage in total share capital (%)
 Proposed repurchase amount                              30,000~60,000
                                                         12 months after the date when the share repurchase plan is
 Proposed repurchase period
                                                         approved at the general meeting
 Purpose of repurchase                                   To reduce registered capital of the Company
 Repurchased number (shares)                             50,959,668
 Percentage of repurchased shares in the target shares
                                                         Not applicable
 under share incentive scheme (%) (if any)
 The progress of the Company's reduction of
                                                         Not applicable
 repurchased shares by centralized bidding
 Remarks                                                 On 11 July 2022, 50,959,668 repurchased shares were cancelled.


          Name of share repurchase plan                        Plan on share repurchase by centralized bidding
 Disclosure date of share repurchase plan                17 October 2022
 Number of shares to be repurchased and its
                                                         0.97~1.95
 percentage in total share capital (%)
 Proposed repurchase amount                              30,000~60,000
                                                         12 months after the date when the share repurchase plan is
 Proposed repurchase period
                                                         approved at the general meeting
 Purpose of repurchase                                   To reduce registered capital of the Company
 Repurchased number (shares)                             10,957,235
 Percentage of repurchased shares in the target shares
                                                         Not applicable
 under share incentive scheme (%) (if any)
 The progress of the Company's reduction of
                                                         Not applicable
 repurchased shares by centralized bidding




                                                           147
Joincare Pharmaceutical Group                                      Annual Report 2022




                       Chapter 8 Information on Preferred Shares

□Applicable √N/A




                                          148
Joincare Pharmaceutical Group                                                Annual Report 2022




                                Chapter 9 Information on Bonds
I. Corporate Bonds, Debentures and Debt Financing Instruments Issued by Non-Financial Entities
□Applicable √N/A


II. Convertible Corporate Bonds
□Applicable √N/A




                                             149
Joincare Pharmaceutical Group                                              Annual Report 2022




                            Chapter 10 Financial Statements
I    Auditor’s report
√Applicable □N/A


                                                      GTCNSZ(2023)NO.442A008607



To all shareholders of Joincare Pharmaceutical Group Industry Co., Ltd.:

I. Auditor's Opinion

We have audited the financial statements of Joincare Pharmaceutical Group Industry Co.,
Ltd. (健康元药业集团股份有限公司) (the “Group”), which comprise the Consolidated
and Company balance sheets as at 31 December 2022, and the Consolidated and Company
income statements, the Consolidated and Company cash flow statements, the Consolidated
and Company statements of changes in shareholders' equity for the year ended 2022, and
notes to the financial statements.

In our opinion, the accompanying financial statements present fairly, in all material respects,
the Consolidated and Company financial positions as at 31 December 2022, and their
financial performance and their cash flows for the year then ended in accordance with the
requirements of Accounting Standards for Business Enterprises.

II. Basis for Opinion
We conducted our audit in accordance with China Standards on Auditing. Our
responsibilities under those standards are further described in the Auditor's Responsibilities
for the Audit of the Financial Statements section of our report. We are independent of the
Company and have fulfilled our other ethical responsibilities in accordance with the China
Code of Ethics for Certified Public Accountants. We believe that the audit evidence we
have obtained is sufficient and appropriate to provide a basis for our opinion.

III. Key Audit Matters

Key audit matters are those matters that, in our professional judgment, were of most
significance in our audit of the financial statements for the current year. These matters were
addressed in the context of our audit of the financial statements as a whole, and in forming
our opinion thereon, and we do not provide a separate opinion on these matters.

(I) Revenue recognition

For relevant disclosure, please refer to Note III. 28 and Note V. 43 to the financial
statements.

1. Description of the matter

The Group generated revenue from primary operation in year ended 31 December 2022
were RMB 17,036.97 million. We identified revenue recognition as a key audit matter due



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Joincare Pharmaceutical Group                                              Annual Report 2022



to the materiality of revenue to the financial statements as a whole and the risk of material
misstatement as to the occurrence and accuracy for in the appropriate accounting period.

2. Addressed in the context of our audit

(1) We obtained an understanding of and assessed the Company management's design and
operating effectiveness of key internal controls over revenue recognition.

(2) We obtained the contracts signed between the Company and its customers and verified
the key terms of the contracts, such as shipment and acceptance, payment and settlement,
exchange and return policies.

(3) We inquired about the business registration information of the Company's customers
and asked relevant personnel of the Company in order to confirm whether there was an
affiliated relationship between the Company and its customers; obtained an understanding
of the reasons for customer changes and contract performance among others; counted and
analyzed end sales of products purchased by selected customers from the Company based
on the business system of the Company's directly connected customers.

(4) We obtained records of returns and exchanges in the Company's business system and
checked them to confirm whether there were significant abnormalities that affected revenue
recognition.

(5) For revenue transactions recorded in the year ended 31 December 2022, we selected
samples to check contracts, purchase orders, shipping documents, transportation documents,
bookkeeping vouchers, payback documents, periodic reconciliation letters and other
supporting documents; and selected samples to perform external confirmation procedures
on major customer sales and accounts receivable.

(6) We performed analytical procedures for the reasonableness on changes in revenue by
considering the product type and factors such as market trends, industry trends, business
expansion plan as well as market data collected by third-party consultants.

(7) We selected samples of revenue transactions around the balance sheet date, reviewed
sales contracts, purchase orders, shipping documents, transportation documents, and
bookkeeping vouchers, and evaluated whether revenues were recorded in the appropriate
accounting period.

(II) Allowance for bad debts on accounts receivable

For relevant disclosure, please refer to Note III. 10 and Note V. 4 to the financial statements

1. Description of the matter

As of 31 December 2022, the Group's closing balance of accounts receivable as reported in
the consolidated balance sheet was RMB 3,176.23 million and the allowance for bad debts
was RMB 72.48 million which were material to the financial statements as a whole. The
management is required to apply significant accounting estimates and judgments in
assessing the expected recoverable amount of accounts receivable, which could have a
material impact on the financial statements if they were not collected on time or were not
recovered resulting in a bad debt loss. Therefore, we identified allowance for bad debts of
accounts receivable as a key audit matter.

2. Addressed in the context of our audit

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Joincare Pharmaceutical Group                                            Annual Report 2022



(1) We obtained an understanding of and assessed the management's design and operating
effectiveness of key internal controls over the management of accounts receivable

(2) We obtained an understanding of the methodology and process of recognizing the
expected credit loss ratio and the key parameters and assumptions applied in the expected
credit loss model, including the method of assessing the customers' credit risk
characteristics for the grouping accounts receivable and the historical migration rate data
used in the expected loss ratio; evaluated whether the expected credit loss ratio was set by
taking into account and was appropriately adjusted for current economic conditions and
forward-looking information, and assessed the reasonableness of the estimate of the
allowance for bad debts.

(3) We obtained a schedule of allowance for bad debts on accounts receivable and checked
whether the calculation method was implemented in accordance with the policy for bad
debts; and recalculated the amount of allowance for bad debts to ensure its accuracy.

(4) We analysed the ratio of the closing balance of allowance for bad debts to accounts
receivable and compared the allowance for bad debts in the previous period to the actual
amount, and analyzed whether the allowance for bad debts on accounts receivable was
adequate.

(5) We evaluated the reasonableness of the allowance for bad debts by analyzing the aging
of accounts receivable and the reputation of customers, and performing audit procedures
such as audit confirmation and subsequent collection of receivables.

IV. Other Information

Management of the Company is responsible for the other information. The other
information comprises the information included in the Company’s 2022 annual report, but
does not include the financial statements and our auditor's report thereon.

Our opinion on the financial statements does not cover the other information and we do not
express any form of assurance conclusion thereon.

In connection with our audit of the financial statements, our responsibility is to read the
other information and, in doing so, consider whether the other information is materially
inconsistent with the financial statements or our knowledge obtained in the audit or
otherwise appears to be materially misstated.

If, based on the work we have performed, we conclude that there is a material misstatement
of this other information, we are required to report that fact. We have nothing to report in
this regard.

V. Responsibilities of Management and Those Charged with Governance for the
Financial Statements

Management of the Company is responsible for the preparation of the financial statements
to achieve fair presentation in accordance with Accounting Standards for Business
Enterprises, and for the design, implementation and maintenance of such internal control
as management determine is necessary to enable the preparation of the financial statements
that are free from material misstatement, whether due to fraud or error.



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Joincare Pharmaceutical Group                                               Annual Report 2022



In preparing the financial statements, management is responsible for assessing the
Company's ability to continue as a going concern, disclosing, as applicable, matters related
to going concern and using the going concern basis of accounting unless management either
intend to liquidate the Company or to cease operations, or have no realistic alternative but
to do so.

Those charged with governance are responsible for overseeing the Company's financial
reporting process.

VI. Auditor's Responsibilities for the Audit of the Financial Statements

Our objectives are to obtain reasonable assurance about whether the financial statements as
a whole are free from material misstatement, whether due to fraud or error, and to issue an
auditor's report that includes our opinion. Reasonable assurance is a high level of assurance,
but is not a guarantee that an audit conducted in accordance with auditing standards will
always detect a material misstatement when it exists. Misstatements can arise from fraud
or error and are considered material if, individually or in the aggregate, they could
reasonably be expected to influence the economic decisions of users taken on the basis of
these financial statements.

As part of an audit in accordance with auditing standards, we exercise professional
judgment and maintain professional skepticism throughout the audit. We also:

(1) Identify and assess the risks of material misstatement of the financial statements,
whether due to fraud or error, design and perform audit procedures responsive to those risks,
and obtain audit evidence that is sufficient and appropriate to provide a basis for our opinion.
The risk of not detecting a material misstatement resulting from fraud is higher than for
one resulting from error, as fraud may involve collusion, forgery, intentional omissions,
misrepresentations, or the override of internal control.

(2) Obtain an understanding of internal control relevant to the audit in order to design audit
procedures that are appropriate in the circumstances.

(3) Evaluate the appropriateness of accounting policies used and the reasonableness of
accounting estimates and related disclosures made by management.

(4) Conclude on the appropriateness of the management’s use of the going concern basis
of accounting and, based on the audit evidence obtained, whether a material uncertainty
exists related to events or conditions that may cast significant doubt on the Company's
ability to continue as a going concern. If we conclude that a material uncertainty exists, the
auditing standards require us to draw attention to users of the financial statements in our
auditor's report to the related disclosures in the financial statements or, if such disclosures
are inadequate, to modify our opinion. Our conclusions are based on the audit evidence
obtained up to the date of our auditor's report. However, future events or conditions may
cause the Company to cease to continue as a going concern.

(5) Evaluate the overall presentation, structure and content of the financial statements,
including the disclosures, and whether the financial statements represent the underlying
transactions and events in a manner that achieves fair presentation.

(6) Obtain sufficient appropriate audit evidence regarding the financial information of the
entities or business activities within the Company to express an opinion on the financial


                                              153
Joincare Pharmaceutical Group                                               Annual Report 2022



statements. We are responsible for the direction, supervision and performance of the group
audit. We remain solely responsible for our audit opinion.

We communicate with those charged with governance regarding, among other matters, the
planned scope and timing of the audit and significant audit findings, including any
significant deficiencies in internal control that we identify during our audit.

We also provide those charged with governance with a statement that we have complied
with relevant ethical requirements regarding independence, and to communicate with them
all relationships and other matters that may reasonably be thought to bear on our
independence, and where applicable, related safeguards.

From the matters communicated with those charged with governance, we determine those
matters that were of most significance in the audit of the financial statements of the current
period and are therefore the key audit matters. We describe these matters in our auditor's
report unless law or regulation precludes public disclosure about the matter or when, in
extremely rare circumstances, we determine that a matter should not be communicated in
our report because the adverse consequences of doing so would reasonably be expected to
outweigh the public interest benefits of such communication.




 Grant Thornton(Special General               Certified Public Accountants Wang Yuan
 Partnership)                                 (The partner in charge of the auditing service project)


                                               Certified Public Accountants      Wang Qilai


 Beijing, China                                7 April 2023




                                             154
    Joincare Pharmaceutical Group                                                       Annual Report 2022


    II    Financial statements
                                           Consolidated Balance Sheet
                                                December 31, 2022

    Prepared by: Joincare Pharmaceutical Group Industry Co., Ltd.
                                                                            Unit: Yuan Currency: RMB
                       Item                           Note      December 31, 2022          December 31, 2021

Current assets:
  Cash and bank balances                               V.1          14,808,488,110.96          11,729,230,390.98
  Financial assets held for trading                    V.2             109,015,664.98             184,638,344.31
  Notes receivable                                     V.3           1,959,985,016.85           1,977,286,022.02
  Accounts receivable                                  V.4           3,103,758,850.15           2,853,655,551.54
  Receivables financing
  Prepayments                                          V.5            364,265,142.57              369,232,546.29
  Other receivables                                    V.6             52,535,740.14               88,053,825.12
  In which: Interests receivable                                                                      365,873.64
             Dividends receivable
  Inventories                                          V.7           2,561,869,999.57           2,078,944,387.68
  Contract assets
  Assets held-for-sale
  Non-current assets due within one year               V.8              54,048,611.11                 317,381.23
  Other current assets                                 V.9             163,539,900.32              83,986,214.37
     Total current assets                                           23,177,507,036.65          19,365,344,663.54
Non-current assets:
  Debt investment
  Other debt investment
  Long-term receivables                               V.10                                            266,904.13
  Long-term equity investment                         V.11           1,419,882,594.59           1,419,349,454.84
  Other equity instrument investment                  V.12           1,193,958,879.05           1,408,882,377.42
  Other non-current financial assets
  Investment properties                               V.13               6,191,475.43               6,191,475.43
  Fixed assets                                        V.14           5,265,200,110.91           4,839,005,169.81
  Construction in progress                            V.15             811,300,068.96             742,998,743.75
  Productive biological assets
  Oil and gas assets
  Right-of-use assets                                 V.16              41,843,133.97              46,774,759.69
  Intangible assets                                   V.17             802,115,125.75             456,782,094.80
  Development cost                                    V.18             428,284,884.17             786,993,435.71
  Goodwill                                            V.19             614,468,698.73             614,468,698.73
  Long-term prepaid expenses                          V.20             277,867,716.95             200,715,740.93
  Deferred tax assets                                 V.21             533,861,743.26             552,542,866.71
  Other non-current assets                            V.22           1,156,772,182.99             663,584,003.80
     Total non-current assets                                       12,551,746,614.76          11,738,555,725.75
       Total assets                                                 35,729,253,651.41          31,103,900,389.29
Current liabilities:
  Short-term loans                                    V.23           2,126,050,615.06           2,518,484,835.09
  Financial liabilities held for trading              V.24                 755,634.43                 143,302.24
  Notes payable                                       V.25           1,635,906,989.22           1,582,386,767.93
  Accounts payable                                    V.26             943,905,580.91             871,553,210.51
  Receipts in advance
  Contract liabilities                                V.27             292,977,730.74             234,140,702.29
  Employee benefits payable                           V.28             573,010,571.46             475,430,823.20
  Taxes payable                                       V.29             337,702,273.73             270,618,183.41
  Other payables                                      V.30           3,680,334,360.88           3,292,407,989.79
                                                       155
    Joincare Pharmaceutical Group                                                                 Annual Report 2022


  In which: Interests payable
             Dividends payable                                                    12,252,074.84               6,951,984.46
  Liabilities held-for-sale
  Non-current liabilities due within one year              V.31                63,077,260.98                 91,576,066.33
  Other current liabilities                                V.32               101,276,714.35                 15,626,224.29
     Total current liabilities                                              9,754,997,731.76              9,352,368,105.08
Non-current liabilities:
  Long-term loans                                          V.33             3,230,844,042.88                826,780,252.78
  Bonds payable
  Lease liabilities                                        V.34                   23,482,486.07              25,071,794.32
  Long-term payables
  Long-term payroll payable
  Estimated liabilities
  Deferred income                                          V.35               384,537,267.55                433,543,352.40
  Deferred tax liabilities                                 V.21               231,164,425.48                208,525,905.39
  Other non-current liabilities                            V.36                84,000,000.00                 78,000,000.00
     Total non-current liabilities                                          3,954,028,221.98              1,571,921,304.89
       Total liabilities                                                   13,709,025,953.74             10,924,289,409.97
Owner's equity (or shareholder's equity):
  Share capital                                            V.37             1,929,189,374.00              1,907,727,908.00
  Other equity instruments
  In which: Preferred shares
            Perpetual debts
  Capital reserve                                          V.38             2,343,693,215.99               2,265,357,311.92
  Less: Treasury shares                                    V.39               347,176,561.29                 222,644,454.50
  Other comprehensive income                               V.40                 4,704,473.53                   5,387,545.97
  Special reserve
  Surplus reserve                                          V.41               734,766,581.50                640,821,179.08
  Undistributed profits                                    V.42             8,456,643,326.82              7,223,644,166.22
  Total shareholders' equity attributable to the parent                    13,121,820,410.55             11,820,293,656.69
  Minority shareholder's equity                                             8,898,407,287.12              8,359,317,322.63
     Total owner's equity (or shareholder's equity)                        22,020,227,697.67             20,179,610,979.32
      Total liabilities and owner's equity (or
                                                                           35,729,253,651.41             31,103,900,389.29
      shareholder's equity)

Person-in-charge of the Company:             Person-in-charge of the Company’s            Person-in-charge of the accounting
           Zhu Baoguo                         accounting work: Qiu Qingfeng                    department: Qiu Qingfeng




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   Joincare Pharmaceutical Group                                                       Annual Report 2022




                                           Balance Sheet of the Parent Company
                                               December 31, 2022

   Prepared by: Joincare Pharmaceutical Group Industry Co., Ltd.
                                                                                Unit: Yuan Currency: RMB
                  Item                        Note          December 31, 2022           December 31, 2021
Current assets:
  Cash and bank balances                                          3,148,933,185.29             1,370,906,734.13
  Financial assets held for trading
  Notes receivable                                                 249,617,024.89                374,296,302.21
  Accounts receivable                                              291,630,857.74                535,543,070.24
  Receivable financing
  Prepayments                                                      542,966,676.99                201,605,530.55
  Other receivables                                                785,307,024.78              1,136,237,811.25
  In which: Interest receivable
             Dividends receivable                                  544,999,500.00                814,041,000.00
  Inventories                                                       63,656,837.97
  Contract assets
  Assets held-for-sale
  Non-current assets due within one year                             54,048,611.11
  Other current assets                                                                             9,379,100.23
     Total current assets                                         5,136,160,218.77             3,627,968,548.61
Non-current assets:
  Debt investment
  Other debt investment
  Long-term receivables
  Long-term equity investment                                     3,524,184,512.63             3,530,939,152.29
  Other equity instrument investment                                141,562,064.27               372,609,966.35
  Other non-current financial assets
  Investment properties                                              6,191,475.43                  6,191,475.43
  Fixed assets                                                      46,410,672.12                 45,139,232.27
  Construction in progress                                          15,330,867.65                  7,890,737.14
  Productive biological assets
  Oil and gas assets
  Right-of-use assets                                                7,570,096.21                 12,470,703.77
  Intangible assets                                                 20,154,211.97                 15,316,963.24
  Development cost                                                  92,797,615.87                 21,304,063.68
  Goodwill
  Long-term prepaid expenses                                            552,795.74                   900,737.50
  Deferred tax assets                                                88,792,276.83               134,711,371.96
  Other non-current assets                                          815,024,705.98                54,866,150.94
     Total non-current assets                                     4,758,571,294.70             4,202,340,554.57
       Total assets                                               9,894,731,513.47             7,830,309,103.18
Current liabilities:
  Short-term loans                                                 100,091,666.67                450,436,811.38
  Financial liabilities held for trading
  Notes payable                                                    924,199,480.81                358,526,972.01
  Accounts payable                                                 257,832,649.19                461,763,867.32
  Receipts in advance
  Contract liabilities                                               53,648,681.36                31,637,971.91
  Employee benefits payable                                         139,895,738.09                95,624,280.17
  Taxes payable                                                      10,549,309.54                17,190,533.60
  Other payables                                                  1,303,649,356.48               810,207,330.35
                                                      157
   Joincare Pharmaceutical Group                                                            Annual Report 2022
  In which: Interests payable
             Dividends payable
  Liabilities held-for-sale
  Non-current liabilities due within one
                                                                       47,152,440.47                    44,954,632.42
year
  Other current liabilities                                             3,007,795.91                     2,140,860.88
     Total current liabilities                                      2,840,027,118.52                 2,272,483,260.04
Non-current liabilities:
  Long-term loans                                                   1,154,000,000.00                   160,000,000.00
  Bonds payable
  Lease liabilities                                                     3,729,020.22                     7,683,561.03
  Long-term payables
  Long-term payroll payable
  Estimated liabilities
  Deferred income                                                      20,534,000.00                    40,796,000.00
  Deferred tax liabilities                                                997,675.94                    29,371,338.01
  Other non-current liabilities
     Total non-current liabilities                                  1,179,260,696.16                   237,850,899.04
        Total liabilities                                           4,019,287,814.68                 2,510,334,159.08
Owner's equity (or shareholder's equity):
  Paid-in capital                                                   1,929,189,374.00                 1,907,727,908.00
  Other equity instruments
  In which: Preferred shares
            Perpetual debts
  Capital reserve                                                   1,678,414,507.96                 1,605,482,128.64
  Less: Treasury shares                                               347,176,561.29                   222,644,454.50
  Other comprehensive income                                              726,576.72                    77,015,953.08
  Special reserve
  Surplus reserve                                                     646,164,633.12                   552,219,230.70
  Undistributed profits                                             1,968,125,168.28                 1,400,174,178.18
     Total owner's equity (or shareholder's
                                                                    5,875,443,698.79                 5,319,974,944.10
equity)
        Total liabilities and owner's equity
                                                                    9,894,731,513.47                 7,830,309,103.18
(or shareholder's equity)

Person-in-charge of the Company:           Person-in-charge of the Company’s          Person-in-charge of the accounting
           Zhu Baoguo                       accounting work: Qiu Qingfeng                  department: Qiu Qingfeng




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 Joincare Pharmaceutical Group                                                       Annual Report 2022


                                       Consolidated Income Statement
                                          From January to December, 2022

                                                                            Unit: Yuan Currency: RMB
                    Item                          Note              2022                     2021
I. Total revenues                                 V.43           17,142,753,068.82        15,903,688,266.59
In which: Operating revenues                                     17,142,753,068.82        15,903,688,266.59
II. Total operating costs                                        13,784,938,368.95        13,169,412,648.95
In which: Operating costs                         V.43            6,252,265,308.40         5,716,293,887.58
          Operating tax and surcharges            V.44              199,746,357.56           182,816,650.02
          Selling expenses                        V.45            4,950,802,456.16         5,026,812,145.41
          Administrative expenses                 V.46              992,483,591.51           939,253,444.33
          R&D expenses                            V.47            1,742,088,079.94         1,397,131,273.33
          Financial expenses                      V.48             -352,447,424.62            -92,894,751.72
          In which: Interest expenses                               139,016,104.44             90,278,042.69
                   Interest income                                  395,476,309.66           191,964,051.82
     Add: Other income                            V.49              289,868,006.44           247,346,934.96
           Income from investments (loss is
                                                  V.50               55,973,114.29            71,881,264.65
           indicated by “-”)
           In which: Income from investments
                                                                    70,577,657.04             10,281,021.59
           in associates and joint ventures
           Gains from derecognition of
           financial assets at amortized cost
           Gains from net exposure hedges
           (loss is indicated by “-”)
           Gains from changes in fair values
                                                  V.51              -76,262,989.83           -23,506,126.09
           (loss is indicated by “-”)
           Losses of credit impairment (loss is
                                                  V.52               -4,123,743.37            -8,024,112.20
           indicated by “-”)
           Impairment loss of assets (loss is
                                                  V.53             -142,627,936.44           -62,950,978.72
           indicated by “-”)
           Gains from disposal of assets (loss
                                                  V.54                 -705,357.30            24,044,186.55
           is indicated by “-”)
III. Operating profit (loss is indicated by
                                                                  3,479,935,793.66         2,983,066,786.79
“-”)
     Add: Non-operating income                    V.55                8,229,847.57             8,641,830.86
     Less: Non-operating expenses                 V.56               32,060,686.06            39,379,273.69
IV. Total profit (loss is indicated by “-”)                     3,456,104,955.17         2,952,329,343.96
     Less: Income tax expenses                    V.57              562,008,858.69           339,480,305.29
V. Net profit (loss is indicated by “-”)                        2,894,096,096.48         2,612,849,038.67
(I) Classified by business continuity
1. Net profit from ongoing operation (loss
                                                                  2,894,096,096.48         2,612,849,038.67
is indicated by “-”)
2. Net profit from discontinuing operation
(loss is indicated by “-”)
(II) Classified by ownership
1.Net profit attributable to shareholders of
the parent company (loss is indicated by                          1,502,595,840.48         1,328,499,432.05
“-”)
2.Profit and loss of minority shareholders
                                                                  1,391,500,256.00         1,284,349,606.62
(loss is indicated by “-”)
VI. Other comprehensive income, net of tax                          74,606,735.39           -177,686,201.25




                                                         159
   Joincare Pharmaceutical Group                                                              Annual Report 2022
 (I) Other comprehensive income
 attributable to owners of the parent                                       -683,072.44               -110,913,013.31
 company, net of tax
 1. Other comprehensive income that cannot
                                                                         -85,577,350.31                -78,059,481.21
 be reclassified into profit or loss
 (1) Changes from remeasurement of
 defined benefit plans
 (2) Other comprehensive income that
 cannot be reclassified into profit or loss                                2,116,352.61                  6,658,847.65
 under the equity method
 (3) Changes in fair value of investments in
                                                                         -87,693,702.91                -84,718,328.85
 other equity instruments
 (4) Changes in fair value of the enterprise's
 own credit risks
 2. Other comprehensive income that will be
                                                                          84,894,277.87                -32,853,532.10
 reclassified into profit or loss
 (1) Other comprehensive income that can
 be reclassified into profit or loss under the                                  236,421.59                  -13,599.80
 equity method
 (2) Changes in fair value of other debt
 investments
 (3) Amount of financial assets reclassified
 into other comprehensive income
 (4) Provision for credit impairment of other
 debt investments
 (5) Reserve for cash flow hedges
 (6) Exchange differences on translation of
 financial statements denominated in foreign                              84,657,856.28                -32,839,932.30
 currencies
 (7) Others
 (II) Other comprehensive income
 attributable to minority shareholders, net of                            75,289,807.82                -66,773,187.94
 tax
 VII. Total comprehensive income                                       2,968,702,831.87              2,435,162,837.42
 (I) Total comprehensive income attributable
                                                                       1,501,912,768.04              1,217,586,418.74
 to owners of the parent company
 (II) Total comprehensive income
                                                                       1,466,790,063.82              1,217,576,418.68
 attributable to minority shareholders
 VIII. Earnings per share:
 (I) Basic earnings per share (RMB/share)                                          0.7933                      0.6864
 (II) Diluted earnings per share (RMB/share)                                       0.7921                      0.6858

Person-in-charge of the Company:           Person-in-charge of the Company’s            Person-in-charge of the accounting
           Zhu Baoguo                       accounting work: Qiu Qingfeng                    department: Qiu Qingfeng




                                                          160
Joincare Pharmaceutical Group                                                            Annual Report 2022


                             Income Statement of the Parent Company
                                        From January to December, 2022
                                                                                 Unit: Yuan Currency: RMB
                              Item                                   Note        2022               2021

I. Operating revenues                                                       2,373,887,564.78   2,021,173,825.62
    Less: Operating costs                                                   1,612,899,011.80   1,356,825,036.11
          Operating tax and surcharges                                         14,203,470.53      12,392,762.31
          Selling expenses                                                    645,474,076.69     509,217,536.91
          Administrative expenses                                             195,475,435.39     152,344,869.22
          R&D expenses                                                         66,705,404.14      99,273,556.14
          Financial expenses                                                  -38,112,993.67     -18,244,358.04
          In which: Interest expenses                                          25,257,639.51       4,032,165.84
                  Interest income                                              70,313,743.55      22,710,793.68
    Add: Other income                                                          23,934,298.39       1,551,111.38
Income from investments (loss is indicated by “-”)                          991,369,051.76   1,293,747,303.58
In which: Income from investments in associates and joint
                                                                               1,326,243.55       -2,005,822.14
ventures
             Gains from derecognition of financial assets at
amortized cost
Gains from net exposure hedges (loss is indicated by “-”)
Gains from changes in fair values (loss is indicated by “-”)
Losses of credit impairment (loss is indicated by “-”)                       1,856,898.77        -203,993.20
Impairment loss of assets (loss is indicated by “-”)                          -154,249.81         -41,007.68
Gains from disposal of assets (loss is indicated by “-”)
II. Operating profit (loss is indicated by “-”)                            894,249,159.01    1,204,417,837.05
    Add: Non-operating income                                                    232,093.51           75,665.33
    Less: Non-operating expenses                                               1,660,096.56       13,762,938.68
III. Total profit (loss is indicated by “-”)                               892,821,155.96    1,190,730,563.70
      Less: Income tax expenses                                               43,089,198.01      -58,066,575.23
IV. Net profit (loss is indicated by “-”)                                  849,731,957.95    1,248,797,138.93
(1) Net profit from ongoing operation (loss is indicated by “-”)           849,731,957.95    1,248,797,138.93
(II) Net profit from discontinuing operation (loss is indicated
by “-”)
V. Other comprehensive income, net of tax                                     -76,289,376.36     -33,565,798.21
(I) Other comprehensive income not to be reclassified into
                                                                              -76,289,376.36     -33,565,798.21
profit and loss
1. Changes from remeasurement of defined benefit plans
2. Other comprehensive income that cannot be reclassified into
profit or loss under the equity method
3. Changes in fair value of investments in other equity
                                                                              -76,289,376.36     -33,565,798.21
instruments
4. Changes in fair value of the enterprise's own credit risks
(II). Other comprehensive income that will be reclassified into
profit and loss
1. Other comprehensive income that can be reclassified into
profit or loss under the equity method
2. Changes in fair value of other debt investments
(3) Amount of financial assets reclassified into other
comprehensive income
(4) Provision for credit impairment of other debt investments
(5) Reserve for cash flow hedges
(6) Exchange differences on translation of financial statements
denominated in foreign currencies

                                                          161
  Joincare Pharmaceutical Group                                                         Annual Report 2022
 (7) Others
 VI. Total comprehensive income                                              773,442,581.59   1,215,231,340.72
 VII. Earnings per share:
 (1) Basic earnings per share (RMB/share)
 (2) Diluted earnings per share (RMB/share)

Person-in-charge of the Company:        Person-in-charge of the Company’s       Person-in-charge of the accounting
           Zhu Baoguo                    accounting work: Qiu Qingfeng               department: Qiu Qingfeng




                                                      162
  Joincare Pharmaceutical Group                                                              Annual Report 2022


                                   Consolidated Cash Flow Statement
                                       From January to December, 2022

                                                                                  Unit: Yuan Currency: RMB
                                Item                              Note            2022                  2021
  I. Cash flow from operating activities:
  Cash received from sales of goods and rendering of services            18,615,546,255.83       16,302,075,867.93
  Tax refunds received                                                      247,896,245.67          142,987,224.70
  Other cash received related to operating activities             V.58      683,645,734.39          545,037,436.64
  Subtotal of cash inflow from operating activities                      19,547,088,235.89       16,990,100,529.27
  Cash paid for goods and services                                        5,728,697,037.48        4,536,979,552.07
  Cash paid to and on behalf of employees                                 2,260,612,483.52        1,950,726,146.40
  Payments of all types of taxes                                          1,668,389,310.43        1,653,421,224.28
  Other cash paid related to operating activities                 V.58    5,911,684,265.17        6,285,884,561.28
  Subtotal of cash outflow in operating activities                       15,569,383,096.60       14,427,011,484.03
  Net cash flow from operating activities                                 3,977,705,139.29        2,563,089,045.24
  II. Cash flow from investing activities:
  Cash received from disposal of investment                                    270,997,751.54       155,208,882.44
  Cash received from returns on investments                                    144,358,825.55       114,833,282.84
  Net cash received from disposal of fixed assets, intangible
                                                                                 3,096,825.59         9,404,128.73
  assets and other long-term assets
  Net cash received from disposal of subsidiaries and other
                                                                                                       3,311,220.53
  business units
  Other cash received related to investing activities             V.58          13,563,902.59       113,574,087.21
  Subtotal of cash inflow from investing activities                            432,017,305.27       396,331,601.75
  Cash paid for purchase and construction of fixed assets,
                                                                          1,147,832,255.23        1,521,419,292.51
  intangible assets and other long-term assets
  Cash paid for investment                                                     416,183,775.89       786,000,000.00
  Net cash paid for acquisition of subsidiaries and other
  business units
  Other cash paid related to investing activities                 V.58     1,120,168,462.77          53,070,040.41
  Subtotal of cash outflow in investing activities                         2,684,184,493.89       2,360,489,332.92
  Net cash flow from investing activities                                 -2,252,167,188.62      -1,964,157,731.17
  III. Cash flow from financing activities:
  Cash received from capital contribution                                      746,673,937.95       609,358,382.32
  In which: Cash received from investment by minority
                                                                                45,595,924.92       526,782,825.73
  interests of subsidiaries
  Cash received from borrowings                                           5,339,517,086.47        3,534,880,943.19
  Other cash received related to financing activities             V.58      381,066,270.61           37,852,177.42
  Subtotal of cash inflow from financing activities                       6,467,257,295.03        4,182,091,502.93
  Cash repayments of amounts borrowed                                     3,718,797,777.63        2,593,581,286.53
  Cash payments for interest expenses and distribution of
                                                                          1,350,994,668.54        1,271,374,383.55
  dividends or profits
  In which: Dividend paid to minority interests of subsidiaries             961,951,199.52          888,900,577.12
  Other cash payments related to financing activities             V.58      831,342,189.06        1,292,040,186.29
  Subtotal of cash outflow in financing activities                        5,901,134,635.23        5,156,995,856.37
  Net cash flow from financing activities                                   566,122,659.80         -974,904,353.44
  IV. Effect of foreign exchange rate changes on cash                       189,286,934.75          -49,290,130.94
  V. Net increase in cash and cash equivalents                            2,480,947,545.22         -425,263,170.31
  Add: Opening balance of cash and cash equivalents                      11,697,518,141.18       12,122,781,311.49
  VI. Closing balance of cash and cash equivalents                       14,178,465,686.40       11,697,518,141.18

Person-in-charge of the Company:          Person-in-charge of the Company’s             Person-in-charge of the accounting
           Zhu Baoguo                      accounting work: Qiu Qingfeng                     department: Qiu Qingfeng


                                                         163
 Joincare Pharmaceutical Group                                                     Annual Report 2022




                               Cash Flow Statement of Parent Company
                                         From January to December, 2022
                                                                             Unit: Yuan Currency: RMB
                    Item                         Note             2022                    2021
I. Cash flow from operating activities:
Cash received from sales of goods and
                                                               3,146,093,806.02          2,029,373,201.42
rendering of services
Tax refunds                                                           82,831.63
Other cash received related to operating
                                                               2,960,613,006.52            606,516,829.33
activities
Subtotal of cash inflow from operating
                                                               6,106,789,644.17          2,635,890,030.75
activities
Cash paid for goods and services                               1,901,562,593.41            983,814,721.63
Cash paid to and on behalf of employees                          246,881,656.93            181,261,857.67
Payments of all types of taxes                                   103,904,304.93            107,046,894.42
Other cash paid related to operating
                                                               3,109,052,257.96          1,062,779,580.04
activities
Subtotal of cash outflow in operating
                                                               5,361,400,813.23          2,334,903,053.76
activities
Net cash flow from operating activities                          745,388,830.94            300,986,976.99
II. Cash flow from investing activities:
Cash received from disposal of
                                                                 270,997,751.54             68,268,656.05
investment
Cash received from returns on
                                                               1,276,079,344.80            632,000,814.98
investments
Net cash received from disposal of fixed
assets, intangible assets and other long-                             21,000.00                  81,400.00
term assets
Net cash received from disposal of
subsidiaries and other business units
Other cash received related to investing
                                                                    158,470.77             101,013,650.67
activities
Subtotal of cash inflow from investing
                                                               1,547,256,567.11            801,364,521.70
activities
Cash paid for purchase and construction
of fixed assets, intangible assets and other                      11,869,023.45              8,127,874.33
long-term assets
Cash paid for investment                                          10,000,000.00            319,037,191.00
Net cash paid for acquisition of
subsidiaries and other business units
Other cash paid related to investing
                                                               1,084,392,104.38             50,000,000.00
activities
Subtotal of cash outflow in investing
                                                               1,106,261,127.83            377,165,065.33
activities
Net cash flow from investing activities                          440,995,439.28            424,199,456.37
III. Cash flow from financing activities:
Cash received from capital contribution                          701,078,013.03             82,575,556.59
Cash received from borrowings                                  1,500,000,000.00            650,000,000.00
Other cash received related to financing
                                                                                            36,583,025.57
activities
Subtotal of cash inflow from financing
                                                               2,201,078,013.03            769,158,582.16
activities
Cash repayments of amounts borrowed                              854,000,000.00            500,000,000.00



                                                        164
   Joincare Pharmaceutical Group                                                           Annual Report 2022


  Cash payments for interest expenses and
                                                                        299,984,479.95               292,289,892.43
  distribution of dividends or profits
  Other cash payments related to financing
                                                                        740,517,545.44               701,265,930.75
  activities
  Subtotal of cash outflow in financing
                                                                      1,894,502,025.39             1,493,555,823.18
  activities
  Net cash flow from financing activities                               306,575,987.64              -724,397,241.02
  IV. Effect of foreign exchange rate
                                                                         -5,804,971.77                   296,539.18
  changes on cash
  V. Net increase in cash and cash
                                                                      1,487,155,286.09                 1,085,731.52
  equivalents
  Add: Opening balance of cash and cash
                                                                      1,370,906,734.13             1,369,821,002.61
  equivalents
  VI. Closing balance of cash and cash
                                                                      2,858,062,020.22             1,370,906,734.13
  equivalents

Person-in-charge of the Company:             Person-in-charge of the Company’s      Person-in-charge of the accounting
          Zhu Baoguo                          accounting work: Qiu Qingfeng              department: Qiu Qingfeng




                                                           165
          Joincare Pharmaceutical Group                                                                                                                                                                                           Annual Report 2022
                                                                                     Consolidated Statement of Changes in Owner's Equity
                                                                                                          From January to December, 2022
                                                                                                                                                                                                                        Unit: Yuan Currency: RMB
                                                                                                                                              2022

                                                                                                 Owner's equity attributable to the parent company

       Item                                                                                                                                                                                                                         Minority            Total owner's
                                               Other equity instruments                                                   Other                                         General                                                shareholder's equity        equity
                                                                                                 Less: Treasury                           Special
                        Paid-up capital                                       Capital reserve                         comprehensive                  Surplus reserve      risk     Undistributed profits     Subtotal
                                          Preferred    Perpetual                                     shares                               reserve
                                                                     Others                                              income                                        provision
                                            share        debts
I. Balance at the
end of previous        1,907,727,908.00                                       2,265,357,311.92    222,644,454.50         5,387,545.97                 640,821,179.08                  7,223,644,166.22     11,820,293,656.69      8,359,317,322.63    20,179,610,979.32
year
Add: Change of
accounting policies
Correction to errors
of the previous
period
Business
combination
involving
enterprises under
common control
Others
II. Balance in
                       1,907,727,908.00                                       2,265,357,311.92    222,644,454.50         5,387,545.97                 640,821,179.08                  7,223,644,166.22     11,820,293,656.69      8,359,317,322.63    20,179,610,979.32
beginning of year
III. Increase and
decrease of the
                         21,461,466.00                                           78,335,904.07    124,532,106.79          -683,072.44                  93,945,402.42                  1,232,999,160.60      1,301,526,753.86       539,089,964.49      1,840,616,718.35
current year (enter
“-” for decrease)
(I) Total
comprehensive                                                                                                             -683,072.44                                                 1,502,595,840.48      1,501,912,768.04      1,466,790,063.82     2,968,702,831.87
income
(II). Capital
contribution or
                         21,461,466.00                                           72,932,379.32    124,532,106.79                                                                                              -30,138,261.47         -9,149,286.66       -39,287,548.13
reduction from
shareholders
1. Capital
contribution from        72,421,134.00                                          612,201,980.48    724,513,822.62                                                                                              -39,890,708.14         22,487,013.47       -17,403,694.67
shareholders
2. Capitals invested
by other equity
instrument holders
3. Amount of
share-based
                                                                                  9,752,446.67                                                                                                                  9,752,446.67                               9,752,446.67
payment included
in owner's equity
4. Others                -50,959,668.00                                        -549,022,047.83   -599,981,715.83                                                                                                                    -31,636,300.13       -31,636,300.13

                                                                                                                                  166
          Joincare Pharmaceutical Group                                                                                                              Annual Report 2022
(III). Profit
                                                                                              84,973,195.80   -362,530,827.45      -277,557,631.65   -967,251,289.90    -1,244,808,921.55
distribution
1. Accrual of
                                                                                              84,973,195.80     -84,973,195.80
surplus reserve
2. Accrual of
general risk
provision
3. Amount
distributed to
                                                                                                              -277,557,631.65      -277,557,631.65   -967,251,289.90    -1,244,808,921.55
owners (or
shareholders)
4. Others
(IV)     Internal
carrying forward of                                                                            8,972,206.62     92,934,147.57      101,906,354.19      15,012,358.44      116,918,712.63
owner's equity
1. Capital reserve
transferred to
increase capital (or
share capital)
2. Surplus reserve
transferred to
increase capital (or
share capital)
3. Surplus reserve
compensating
losses
4. Retained
earnings carried
over from changes
in the defined
benefit plan
5. Retained
earnings carried
over from other                                                                                8,972,206.62     92,934,147.57      101,906,354.19      15,012,358.44      116,918,712.63
comprehensive
income
6. Others
(V)      . Special
reserve
1. Accrual of the
current year
2. Amount utilized
in the current
period
(VI)     . Others                             5,403,524.75                                                                            5,403,524.75     33,688,118.79       39,091,643.54
IV. Balance at end
                       1,929,189,374.00   2,343,693,215.99   347,176,561.29   4,704,473.53   734,766,581.50   8,456,643,326.82   13,121,820,410.55   8,898,407,287.12   22,020,227,697.67
of year




                                                                                       167
           Joincare Pharmaceutical Group                                                                                                                                                                                        Annual Report 2022

                                                                                                                                                            2021
                                                                                                   Owner's equity attributable to the parent company
       Item                                     Other equity instruments                                                    Other                                         General                                                Minority
                                                                                                   Less: Treasury                            Special                                 Undistributed                                                 Total owner's equity
                        Paid-up capital   Preferred     Perpetual               Capital reserve                         comprehensive                  Surplus reserve      risk                           Subtotal         shareholder's equity
                                                                       Others                          shares                                reserve                                   profits
                                            share          debts                                                           income                                        provision
I. Balance at the
end of previous        1,952,780,764.00                                         2,533,288,674.28    253,637,154.50       116,300,559.28                 515,941,465.19               6,231,451,582.26   11,096,125,890.51     8,140,772,186.49       19,236,898,077.00
year
Add: Change of
accounting policies
Correction to errors
of the previous
period
Business
combination
involving
enterprises under
common control
Others
II. Balance in
                       1,952,780,764.00                                         2,533,288,674.28    253,637,154.50       116,300,559.28                 515,941,465.19               6,231,451,582.26   11,096,125,890.51     8,140,772,186.49       19,236,898,077.00
beginning of year
III. Increase and
decrease of the
                         -45,052,856.00                                          -267,931,362.36    -30,992,700.00       -110,913,013.31                124,879,713.89                992,192,583.96      724,167,766.18        218,545,136.13          942,712,902.32
current year (enter
“-” for decrease)
(I). Total
comprehensive                                                                                                            -110,913,013.31                                             1,328,499,432.05    1,217,586,418.74     1,217,576,418.68        2,435,162,837.42
income
(II). Capital
contribution or
                         -45,052,856.00                                          -570,478,635.27    -30,992,700.00                                                                                       -584,538,791.27        -21,931,055.41         -606,469,846.68
reduction from
shareholders
1. Capital
contribution from        10,082,440.00                                             72,493,116.59    699,900,526.87                                                                                       -617,324,970.28        437,967,405.33         -179,357,564.95
shareholders
2. Capitals invested
by other equity
instrument holders
3. Amount of share-
based payment
                                                                                    1,793,479.01                                                                                                             1,793,479.01                                 1,793,479.01
included in owner's
equity
4. Others                -55,135,296.00                                          -644,765,230.87   -730,893,226.87                                                                                         30,992,700.00       -459,898,460.74         -428,905,760.74
(III). Profit
                                                                                                                                                        124,879,713.89               -413,555,101.94     -288,675,388.05       -887,433,971.08       -1,176,109,359.13
distribution
1. Accrual of
                                                                                                                                                        124,879,713.89               -124,879,713.89
surplus reserve




                                                                                                                                     168
           Joincare Pharmaceutical Group                                                                                                                                            Annual Report 2022
2. Accrual of
general risk
provision
3. Amount
distributed to
                                                                                                                                           -288,675,388.05     -288,675,388.05    -887,433,971.08    -1,176,109,359.13
owners (or
shareholders)
4. Others
(IV)     . Internal
carrying forward of                                                                                                                          77,248,253.85       77,248,253.85      94,678,535.62      171,926,789.47
owner's equity
1. Capital reserve
transferred to
increase capital (or
share capital)
2. Surplus reserve
transferred to
increase capital (or
share capital)
3. Surplus reserve
compensating
losses
4. Retained
earnings carried
over from changes
in the defined
benefit plan
5. Retained
earnings carried
over from other                                                                                                                              77,248,253.85       77,248,253.85      94,678,535.62      171,926,789.47
comprehensive
income
6. Others
(V)      . Special
reserve
1. Accrual of the
current year
2. Amount utilized
in the current
period
(VI)     . Others                                                302,547,272.91                                                                                 302,547,272.91    -184,344,791.68      118,202,481.23
IV. Balance at end
                       1,907,727,908.00                         2,265,357,311.92   222,644,454.50   5,387,545.97          640,821,179.08   7,223,644,166.22   11,820,293,656.69   8,359,317,322.63   20,179,610,979.32
of year


                             Person-in-charge of the Company:                      Person-in-charge of the Company’s accounting work:         Person-in-charge of the accounting department:
                                        Zhu Baoguo                                                     Qiu Qingfeng                                            Qiu Qingfeng




                                                                                                            169
      Joincare Pharmaceutical Group                                                                                                                                                                  Annual Report 2022


                                                                       Statement of Changes in Owner's Equity of the Parent Company
                                                                                                  From January to December, 2022
                                                                                                                                                                                           Unit: Yuan Currency: RMB
                                                                                                                                           2022
                                                                              Other equity instruments                                                Other
                       Item                                                                                                    Less: Treasury                       Special                     Undistributed       Total owner's
                                                     Paid-up capital      Preferre   Perpetual               Capital reserve                      comprehensive               Surplus reserve
                                                                                                   Others                          shares                           reserve                       profits              equity
                                                                          d share      debts                                                         income
I. Balance at the end of previous year               1,907,727,908.00                                       1,605,482,128.64    222,644,454.50      77,015,953.08             552,219,230.70    1,400,174,178.18   5,319,974,944.10
Add: Change of accounting policies
Correction to errors of the previous period
Others
II. Balance in beginning of year                     1,907,727,908.00                                       1,605,482,128.64    222,644,454.50    77,015,953.080              552,219,230.70    1,400,174,178.18   5,319,974,944.10
III. Increase and decrease of the current year
                                                        21,461,466.00                                          72,932,379.32    124,532,106.79    -76,289,376.362               93,945,402.42    567,950,990.10     555,468,754.69
(enter “-” for decrease)
(I). Total comprehensive income                                                                                                                   -76,289,376.362                                849,731,957.95     773,442,581.59
(II) Capital contribution or reduction from
                                                        21,461,466.00                                          72,932,379.32    124,532,106.79                                                                       -30,138,261.47
shareholders
1. Capital contribution from shareholders               72,421,134.00                                        612,201,980.48     724,513,822.62                                                                       -39,890,708.14
2. Capitals invested by other equity instrument
holders
3. Amount of share-based payment included in
                                                                                                                9,752,446.67                                                                                           9,752,446.67
owner's equity
4. Others                                              -50,959,668.00                                       -549,022,047.83    -599,981,715.83
(III). Profit distribution                                                                                                                                                      84,973,195.80   -362,530,827.45    -277,557,631.65
1. Accrual of surplus reserve                                                                                                                                                   84,973,195.80    -84,973,195.80
2. Amount distributed to owners (or shareholders)                                                                                                                                               -277,557,631.65    -277,557,631.65
3. Others
(IV) . Internal carrying forward of owner's
                                                                                                                                                                                 8,972,206.62     80,749,859.60      89,722,066.22
equity
1. Capital reserve transferred to increase capital
(or share capital)
2. Surplus reserve transferred to increase capital
(or share capital)
3. Surplus reserve compensating losses
4. Retained earnings carried over from changes in
the defined benefit plan
5. Retained earnings carried over from other
                                                                                                                                                                                 8,972,206.62     80,749,859.60      89,722,066.22
comprehensive income
6. Others
(V) . Special reserve
1. Accrual of the current year
2. Amount utilized in the current period
(VI) . Others
IV. Balance at end of year                           1,929,189,374.00                                       1,678,414,507.96    347,176,561.29        726,576.72              646,164,633.12    1,968,125,168.28   5,875,443,698.79




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       Joincare Pharmaceutical Group                                                                                                                                                                         Annual Report 2022

                                                                                                                                                2021
                                                                             Other equity instruments                                                       Other
                      Item                                                                                                     Less: Treasury                             Special                      Undistributed
                                                     Paid-up capital    Preferred    Perpetual               Capital reserve                           comprehensive                Surplus reserve                      Total owner's equity
                                                                                                   Others                          shares                                 reserve                        profits
                                                                          share        debts                                                               income
I. Balance at the end of previous year               1,952,780,764.00                                       2,169,622,381.22   253,637,154.50            110,581,751.29              427,339,516.81    564,932,141.19      4,971,619,400.01
Add: Change of accounting policies
Correction to errors of the previous period
Others
II. Opening balance of the current year              1,952,780,764.00                                       2,169,622,381.22   253,637,154.50           110,581,751.29               427,339,516.81    564,932,141.19      4,971,619,400.01
III. Increase and decrease of the current year
                                                       -45,052,856.00                                       -564,140,252.58     -30,992,700.00           -33,565,798.21              124,879,713.89    835,242,036.99        348,355,544.09
(enter “-” for decrease)
(I). Total comprehensive income                                                                                                                          -33,565,798.21                               1,248,797,138.93     1,215,231,340.72
(II). Capital contribution or reduction from
                                                       -45,052,856.00                                       -570,478,635.27     -30,992,700.00                                                                              -584,538,791.27
shareholders
1. Capital contribution from shareholders              10,082,440.00                                           72,493,116.59   699,900,526.87                                                                               -617,324,970.28
2. Capitals invested by other equity instrument
holders
3. Amount of share-based payment included in
                                                                                                                1,793,479.01                                                                                                    1,793,479.01
owner's equity
4. Others                                              -55,135,296.00                                       -644,765,230.87    -730,893,226.87                                                                                30,992,700.00
(III). Profit distribution                                                                                                                                                           124,879,713.89   -413,555,101.94       -288,675,388.05
1. Accrual of surplus reserve                                                                                                                                                        124,879,713.89   -124,879,713.89
2. Amount distributed to owners (or
                                                                                                                                                                                                      -288,675,388.05       -288,675,388.05
shareholders)
3. Others
(IV) . Internal carrying forward of owner's
equity
1. Capital reserve transferred to increase capital
(or share capital)
2. Surplus reserve transferred to increase capital
(or share capital)
3. Surplus reserve compensating losses
4. Retained earnings carried over from changes
in the defined benefit plan
5. Retained earnings carried over from other
comprehensive income
6. Others
(V)       Special reserve
1. Accrual of the current year
2. Amount utilized in the current period
(VI)      Others                                                                                                6,338,382.69                                                                                                   6,338,382.69
IV. Balance at end of year                           1,907,727,908.00                                       1,605,482,128.64   222,644,454.50            77,015,953.08               552,219,230.70   1,400,174,178.18     5,319,974,944.10


                 Person-in-charge of the Company: Zhu Baoguo                                Person-in-charge of the Company’s accounting work:                               Person-in-charge of the accounting department:
                                                                                                               Qiu Qingfeng                                                                   Qiu Qingfeng


                                                                                                                        171
     Joincare Pharmaceutical Group                                                               Annual Report 2022


                     Joincare Pharmaceutical Group Industry Co., Ltd
                                     Notes to the financial statements
                        (All amounts in RMB Yuan unless otherwise stated)



I. Company Profile

1. Company Overview

     The Company is formerly known as Shenzhen Aimier Food Co., Ltd. (深圳爱迷尔食品有限公司), was a
     Sino-foreign joint venture officially established on 18 December 1992 with the approval from Shenzhen
     Administration for Industry and Commerce.

     On 24 November 1999, the Company was reorganized as a joint stock limited company.

     On 6 February 2001, the Company was approved by the China Securities Regulatory Commission to issue
     domestically listed shares (A shares) to the public. On 8 June 2001, shares of the Company were listed and
     traded on Shanghai Stock Exchange.

     As of 31 December 2022, the total share capital of the Company was RMB1,929,189,374 for a total number
     of shares of 1,929,189,374 shares. The controlling shareholder of the Company is Shenzhen Baiyeyuan
     Investment Co., Ltd. (深圳市百业源投资有限公司), and the ultimate controlling party is Zhu Baoguo (朱
     保国).

     The Company is engaged in the pharmaceutical industry.

     The Company and its subsidiaries primarily engaged in the R&D, production and sale of pharmaceutical
     products and healthcare products, which covered drug preparation products, active pharmaceutical
     ingredients (“APIs”) and intermediates, diagnostic reagents and equipment as well as healthcare products.

2. Scope of consolidated financial statements

     The information of subsidiaries included in the scope of consolidation for the year ended 31 December 2022
     refer to Note VII “Equity in other entities” and the information of the changes in scope of consolidation
     during the period refer to Note VI “Changes in scope of consolidation”.

II. Basis of Preparation for the Financial Statements

     The financial statements have been prepared in accordance with the Accounting Standards for Business
     Enterprises issued by the MOF and its application guidance, interpretations and the other related provisions
     (collectively, the “Accounting Standards for Business Enterprises”). In addition, the Company also discloses
     relevant financial information in accordance with the Information Disclosure and Presentation Rules for
     Companies Offering Securities to the Public No. 15 – General Provisions on Financial Reporting (2014
     Revision) issued by the China Securities Regulatory Commission.

     The financial statements have been prepared on the going-concern basis.

     The Company's accounting is measured on an accrual basis. Except for certain financial instruments, the
     financial statements are generally measured at historical cost. Non-current assets held for sale are stated at
     the lower of fair value less estimated selling costs and their original carrying amount if they qualify as held
     for sale. In case of asset impairment, the Company shall make provisions for impairment in accordance with
     applicable provisions.

III. Significant Accounting Policies and Accounting Estimates


                                                          172
     Joincare Pharmaceutical Group                                                                 Annual Report 2022


     The Company determines the depreciation of fixed assets, amortisation of intangible assets, capitalisation
     condition of R&D expenses and revenue recognition policies on the basis of its production and operation
     characteristics. Details of accounting policies are set out in Note III.16, Note III.20, Note III.21 and Note
     III.28.

1. Statement of compliance with the Accounting Standards for Business Enterprises

     The financial statements comply with the Accounting Standards for Business Enterprises, which gave a true
     and complete view of the consolidated and the Company's financial positions as at 31 December 2022, and
     the consolidated and the Company’s operating results and the consolidated and the Company’s cash flows
     and other relevant information for the year ended 31 December 2022.

2. Accounting period

     The fiscal year of the Company is from 1 January to 31 December in each calendar year.

3. Operating cycle

     The Company’s operating cycle is 12 months.

4. Functional currency

     The functional currency of the Company and its domestic subsidiaries is Renminbi (“RMB”). Overseas
     subsidiaries of the Company usually recognise HK dollar, Macau dollar and US dollar as their functional
     currencies according to the primary economic environment of which these subsidiaries operate. The
     Company prepares its financial statements in RMB.

5. Accounting treatment for business combinations involving enterprises under common control and business
    combinations involving enterprises not under common control

(1) Business combinations involving enterprises under common control

     For the business combination involving entities under common control, the assets acquired and liabilities
     assumed are measured based on their carrying amounts in the consolidated financial statements of the
     ultimate controlling party as at the combination date. The difference between the carrying amount of the
     consideration paid for the combination and the net assets acquired is adjusted against share premium in the
     capital reserve, with any excess adjusted against retained earnings.

     Business combination involving enterprises under common control and achieved in a number of transactions

     In the separate financial statements, the initial investment cost will be recognised at the carrying amount of
     the Company's share in the combined party's net assets in the consolidated financial statements of the ultimate
     controlling party on the date of combination. The difference between the initial investment cost and the sum
     of the carrying amount of the investment held and the carrying amount of consideration paid for the
     combination at the combination date is adjusted against share premium in the capital reserve, with any excess
     adjusted against retained earnings.

     In the consolidated financial statements, the assets acquired and liabilities assumed are measured based on
     their carrying amounts in the consolidated financial statements of the ultimate controlling party as at the
     combination date. The difference between sum of the carrying amount of the investment held and the carrying
     amount of the consideration paid for the combination and the carrying amount of the net assets acquired is
     adjusted against share premium in the capital reserve, with any excess adjusted against retained earnings. For
     long-term equity investment held before the control over the combined party is obtained, profit or loss, other
     comprehensive income and other changes to equity interest attributable to the owners recognised from the
     later of the acquisition of the original equity interest and the date when the combing party and the combined
     party are placed under common control until the date of combination shall be offset against retained profit at
     the beginning of the period of the comparative financial statements or profit or loss of the period respectively.

(2) Business combinations involving enterprises not under common control

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     Joincare Pharmaceutical Group                                                                  Annual Report 2022


     For the business combinations involving enterprises not under common control, the combination cost shall
     be the fair value of the assets transferred, liabilities incurred or assumed, and equity securities issued by the
     acquirer for acquisition of control in the acquiree on the acquisition date. The assets, liabilities and contingent
     liabilities acquired or assumed on the date of acquisition are recognised at fair value.

     Where the combination cost exceeds the fair value of the acquiree's identifiable net assets in the business
     combination, the difference is recognised as goodwill and is subsequently measured at cost less accumulated
     impairment provisions. Where the combination cost is less than the fair value of the acquiree's identifiable
     net assets in the business combination, the difference shall be included in profit or loss for the period after
     review.

     Business combination involving enterprises not under common control and achieved in a number of
     transactions

     In the separate financial statements, the initial cost of the investment is the sum of the carrying amount of the
     acquiree's equity investment held before the acquisition date and the additional investment cost on the
     acquisition date. In respect of the equity investment held prior to the acquisition date, other comprehensive
     income will not be recognised using equity method on the acquisition date, and such investment will be
     accounted for on the same accounting treatment as direct disposal of relevant asset or liability by the investee
     at the time of disposal. Shareholder's equity recognised due to the changes of other shareholder's equity other
     than the changes of net loss and profit, other comprehensive income and profit distribution shall be
     transferred to profit or loss for current period when disposed. If the equity investment held prior to the
     acquisition date is measured at fair value, the cumulative changes in fair value recognised in other
     comprehensive income shall be transferred to retained earnings when accounted for using cost method.

     In the consolidated financial statements, the combination cost is the sum of consideration paid on the
     acquisition date and fair value of the acquiree's equity held prior to the acquisition date. The equity of the
     acquirees held before the acquisition date is re-measured at the fair value of the equity on the acquisition date
     and the differences between the fair value and the carrying amount are recognised in the income for the
     current period; in respect of any other comprehensive income attributable to the equity interest in the acquiree
     held prior to the acquisition date and any changes of other shareholder's equity shall be transferred to
     investment profit or loss for current period on the acquisition date, except for the other comprehensive income
     incurred due to the changes arising from remeasuring net assets or net liabilities of defined benefit plan
     attributable to the acquiree.

(3) Transaction fees attribution during the combination

     The intermediary and other relevant administrative expenses such as audit, legal and valuation advisory for
     business combinations are recognised in profit or loss when incurred. Transaction costs of equity or debt
     securities issued as the considerations of business combination are included in the initial recognition amounts.

6. Preparation of consolidated financial statements

(1) Scope of consolidation

     The scope of consolidated financial statements is determined based on control. Control means the Company
     has exposures or rights to variable returns from its involvement with the investee and the ability to affect
     those returns through power over such investee. Subsidiaries are the entities controlled by the Company
     (including enterprises, a dividable part of investees and structured entities).

(2) Method for preparation of the consolidated financial statements

     The consolidated financial statements are based on the financial statements of the Company and its
     subsidiaries, and are prepared by the Company in accordance with other relevant information. In preparing
     the consolidation financial statements, the Company and its subsidiaries are required to apply consistent
     accounting policy and accounting period, intra-group transactions and balances shall be offset.

     A subsidiary or a business acquired through a business combination involving entities under common control


                                                            174
     Joincare Pharmaceutical Group                                                                 Annual Report 2022


     in the reporting period shall be included in the scope of the consolidation of the Company from the date when
     it is under control of the ultimate controlling party, and then its operating results and cash flows will be
     included in the consolidated income statement and the consolidated cash flow statement, respectively.

     For a subsidiary or a business acquired through a business combination involving entities not under common
     control in the reporting period, its income, expenses and profits are included in the consolidated income
     statement, and its cash flows are included in the consolidated cash flow statement from the acquisition date
     to the end of the reporting date.

     The shareholders' equity of the subsidiaries that are not attributable to the Company shall be presented under
     shareholders' equity in the consolidated balance sheet as minority interests. The portion of net profit or loss
     of subsidiaries for the period attributable to minority interest is presented in the consolidated income
     statement under the “profit or loss of minority interest”. When the amount of loss attributable to the minority
     shareholders of a subsidiary exceeds the minority shareholders' portion of the opening balance of owners'
     equity of the subsidiary, the excess amount shall be allocated against minority interest.

(3) Purchase of the minority stake in the subsidiary

     The difference between the long-term equity investments costs acquired by the purchase of minority interests
     and the share of the net assets that the subsidiaries have to continue to calculate from the date of purchase or
     the date of consolidation in proportion to the new shareholding ratio, and the difference between the disposal
     of the equity investment without losing control over its subsidiary and the disposal of the long-term equity
     investment corresponding to the share of the net assets of the subsidiaries from the date of purchase or the
     date of consolidation, shall be adjusted to the capital reserve (or share premium), if the capital reserve is not
     sufficient, any excess will be adjusted to retained earnings.

(4) Treatment of loss of control of subsidiaries

     Where the Company loses its control over the original subsidiary due to the disposal of some equity
     investment or other reasons, the remaining equity is re-measured at its fair value on the date when the
     Company loses its control. The difference between the sum of the consideration acquired due to the disposal
     of the equity and the fair value of the remaining equity, and the Company's share in the sum of carrying value
     of net assets of the original subsidiary and goodwill calculated on an ongoing basis from the acquisition date
     based on the original shareholding proportion is recognised in the investment income for the current period
     when the control is lost.

     Other comprehensive income in relation to the original subsidiary's equity investment are transferred to profit
     or loss for the current period when control ceases, except for those arising from re-measuring net assets or
     net liabilities of defined benefit plan by the investee.

(5) Treatment of disposal through several transactions until the loss of control of subsidiaries

     Where the Company disposes of the equity interests in the subsidiary through several transactions until it
     loses control, and the transaction terms, conditions and economic effects satisfy one or several of the
     following circumstances, such several transactions shall be deemed as a basket of transactions in accounting
     treatment:

     ① Such transactions are entered into simultaneously or upon the consideration of the mutual impacts;

     ② No complete commercial result will be realised without such transactions as a whole;

     ③ The occurrence of one transaction depends on the occurrence of at least another transaction;

     ④ The result of an individual transaction is not economical, but it would be economical after taken into
     account of other transactions in the series.

     In the separate financial statements, where the Company disposes of the equity investment in the subsidiary
     through several transactions until the loss of control, and such transactions are not regarded as “a basket of

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     Joincare Pharmaceutical Group                                                                Annual Report 2022


     transactions”, the carrying amount of the long-term equity investment involving each disposal will be carried
     forward, with the difference between the disposal price and the carrying amount of the long-term equity
     investment involving the disposal being accounted into the investment incomes for the current period; where
     the transactions constitute “a basket of transactions”, the difference between the consideration of each
     disposal and the carrying amount of the long-term equity investment involving the disposal before the loss
     of the control, is recognised as the other comprehensive income and will be carried forward to the profit or
     loss for the current period when the control is lost.

     In the consolidated financial statements, where the Company disposes of the equity investment in the
     subsidiary through several transactions until the loss of control, the measurement of the remaining equity
     interest and the accounting treatment of the losses and gains of the disposal will be made with reference to
     the “Treatment of loss of control of subsidiaries” as described above. For the difference between the
     consideration of each disposal before the loss of the control and the carrying amount of the Company's share
     in the net assets involving the disposal of such subsidiary calculated on an on-going basis from the acquisition
     date, the treatment will be made as follows:

     ① In case the transactions are “a basket of transactions”, such difference is recognised as the other
     comprehensive income and will be carried forward to the profit or loss for the current period when the control
     is lost.

     ② In case the transactions are not “a basket of transactions”, such difference is accounted into the capital
     reserve (or share premium) as equity, and shall not be carried forward to the profit or loss for the current
     period when the control is lost.

7. Classification of joint arrangement and accounting treatment for joint operation

     A joint arrangement is an arrangement jointly controlled by two or more parties. The Company's joint
     arrangement is classified into the joint operation and the joint venture.

(1) Joint operation

     A joint operation is a joint arrangement whereby the Company have rights and obligations to the relevant
     assets and liabilities.

     The Company recognises the following items in relation to its interest in a joint operation, and makes
     corresponding accounting treatment in accordance with relevant accounting standards:

     A. The solely-held assets, and the share of any assets held jointly;

     B. The solely-assumed liabilities, and its share of any liabilities incurred jointly;

     C. Its revenue from the sale of its share of the output arising from the joint operation;

     D. Its share of the revenue from the sale of the output by the joint operation;

     E. The solely-incurred expenses, including its share of any expenses incurred jointly.

(2) Joint ventures

     A joint venture is a joint arrangement whereby the Company only entitled to the net assets of the arrangements.

     The Company's investment in joint ventures is accounted for using the equity method according to the rules
     of the long-term equity investment.

8. Determination of cash and cash equivalents

     Cash and cash equivalents of the Company include cash on hand, bank deposit readily available for payment
     and those investments held by the Company that are short-term (normally due in three months since the
     acquisition date), highly liquid, readily convertible into known amounts of cash and subject to an insignificant

                                                            176
     Joincare Pharmaceutical Group                                                                  Annual Report 2022


     risk of change in value.

9. Foreign currency transactions and translation of financial statements in foreign currency

(1) Foreign currency transactions

     Foreign currency transactions incurred by the Company are translated to the functional currency at the spot
     exchange rates on the date of the transactions upon initial recognition.

     Monetary items denominated in foreign currencies are translated to functional currency at the spot exchange
     rate on the balance sheet date. Exchange differences arising from the differences between the spot exchange
     rate prevailing at the balance sheet date and those spot rates used on initial recognition or at the previous
     balance sheet date are recognised in profit or loss for the current period; non-monetary items denominated in
     foreign currencies that are measured at historical cost are translated using the spot exchange rate on the
     transaction date. Non-monetary items denominated in foreign currencies that are measured at fair value are
     translated using the spot exchange rate on the date the fair value is determined; the resulting exchange
     differences between the amounts in functional currency upon translation and in original functional currency
     are recognised in profit or loss for the current period.

(2) Translation of financial statements in foreign currency

     At the balance sheet date, when translating the foreign currency financial statements of overseas subsidiaries,
     the assets and liabilities in the balance sheet are translated at the spot exchange rate at the balance sheet date;
     all items except for “Retained earnings” of the shareholders' equity are translated at the spot exchange rate
     on the transaction date.

     The revenue and expenses in profit or loss are translated at the spot exchange rate on the transaction date.

     All items in the statement of cash flows are translated at the spot exchange rate on the transaction date. The
     effect of exchange difference on cash is adjusted and separately presented as “Effect of changes in foreign
     exchange rates on cash and cash equivalents” in the cash flow statement.

     The exchange differences arising from translation of the financial statements are presented as the “other
     comprehensive income” in the shareholders' equity of the balance sheet.

     When the Company disposes of the overseas operation and loses control, the differences arising from the
     translation of the financial statements in foreign currency that have been presented under the shareholders'
     equity in the balance sheet and involving such overseas operation are carried forward to the profit or loss for
     the current period in whole or in the proportion of the disposal of the overseas operation.

10. Financial instruments

     Financial instruments are contracts creating financial assets of a party and financial liabilities or equity
     instruments of other parties.

(1) Recognition and Derecognition of financial instruments

     A financial asset or financial liability is recognised when the Company becomes one of the parties under a
     financial instrument contract.

     The financial assets will be derecognised if any of the following conditions is satisfied:

     ① The contractual right to receive the cash flow of the financial assets is terminated;

     ② The financial assets have been transferred and the transferred financial asset satisfies the following
     conditions of derecognition.

     If the current obligation of a financial liability (or a part thereof) has been discharged, the financial liability
     (or that part of the financial liability) will be derecognised. When the Company (as the debtor) and the lender

                                                              177
     Joincare Pharmaceutical Group                                                                   Annual Report 2022


     have signed an agreement which uses a new financial liability to replace the existing financial liability, and
     the contract terms of the new financial liability are substantially different with the original financial liability,
     the original financial liability shall be de-recognised, and the new financial liability shall be recognised at
     the same time.

     The regular transactions of the financial assets are recognised and derecognised at the transaction date.

(2) Classification and measurement of financial assets

     The Company classifies financial assets into three categories: financial assets at amortised cost; financial
     assets at fair value through other comprehensive income; and financial assets at fair value through profit or
     loss based on the business model for managing financial assets and their contractual cash flow characteristics
     upon initial recognition.

     Financial assets at amortised cost

     The Company shall classify financial assets that meet the following conditions and are not designated as
     financial assets at fair value through profit or loss for the current period as financial assets measured at
     amortised cost:

         The Company's business model for managing the financial assets is to collect contractual cash flow;

         The terms of the financial asset contract stipulate that the cash flow generated on a specific date is only
         the payment for principal and interest accrued on the outstanding principal.

     After initial recognition, these financial assets are measured at amortised cost using the effective interest
     method. Gains or losses arising from financial assets which are measured at amortised cost and not part of
     any hedging relationship are included in the profit and loss of the current period upon de-recognition,
     amortisation using the effective interest method, or impairments recognition.

     Financial assets at fair value through other comprehensive income

     The Company shall classify financial assets that meet the following conditions and are not designated as
     financial assets measured at fair value through profit or loss for the current period as financial assets measured
     at fair value through other comprehensive income

         The Company's business model for managing the financial assets is both to collect contractual cash
         flows and to sell the financial assets;

         The terms of the financial asset contract stipulate that the cash flow generated on a specific date is only
         the payment for principal and interest accrued on the outstanding principal.

     After initial recognition, these financial assets are subsequently measured at fair value. Interest, impairment
     losses or gains and exchange losses and gains calculated using the effective interest method are recognised
     in profit or loss for the current period, while other gains or losses are recognised in other comprehensive
     income. The cumulative profit or loss previously included in other comprehensive income will be transferred
     to the profit or loss for the current period upon derecognition of the financial assets.

     Financial assets at fair value through profit or loss for the current period

     In addition to the above financial assets which are measured at amortised cost or at fair value a through other
     comprehensive income, the Company classifies all other financial assets as financial assets measured at fair
     value through profit or loss for the current period. When initial recognition, in order to eliminate or
     significantly reduce accounting mismatches, the Company irrevocably designates some financial assets that
     should have been measured at amortised cost or at fair value through other comprehensive income as financial
     assets at fair value through profit or loss for the current period.

     After initial recognition, these financial assets are subsequently measured at fair value, and the profits or
     losses (including interest and dividend income) generated from which are recognised in profit or loss for the

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     Joincare Pharmaceutical Group                                                                    Annual Report 2022


     current period, unless the financial assets are part of the hedging relationship.

     However, with respect to non-trading equity instrument investments, the Company may irrevocably designate
     them as financial assets measured at fair value through other comprehensive income at initial recognition.
     The designation is made on the basis of individual investment, and the relevant investment conforms to the
     definition of equity instruments from the issuer's point of view.

     After initial confirmation, financial assets are subsequently measured at fair value. Dividend income that
     meets the requirements is recognised in profit and loss, and other gains or losses and changes in fair value
     are recognised in other comprehensive gains. When derecognised, the accumulated gains or losses previously
     recognised in other comprehensive gains are transferred from other comprehensive gains to retained earnings.

     The business model of managing financial assets refers to how the Company manages financial assets to
     generate cash flow. The business model decides whether the source of cash flow of financial assets managed
     by the Company is to collect contract cash flow, sell financial assets or both of them. Based on objective facts
     and the specific business objectives of financial assets management decided by key managers, the Company
     determines the business model of financial assets management.

     The Company evaluates the characteristics of the contract cash flow of financial assets to determine whether
     the contract cash flow generated by the relevant financial assets on a specific date is only to pay principal
     and interest based on the amount of unpaid principal. Among them, principal refers to the fair value of
     financial assets at the time of initial confirmation; interest includes the consideration of time value of money,
     credit risk related to the amount of unpaid principal in a specific period, and other basic borrowing risks,
     costs and profits. In addition, the Company evaluates the terms and conditions of the contracts that may lead
     to changes in the time distribution or amount of cash flow in financial asset contracts to determine whether
     they meet the requirements of the above contract cash flow's characteristics.

     Only when the Company changes its business model of managing financial assets, all the financial assets
     affected shall be reclassified on the first day of the first reporting period after the business model changes,
     otherwise, financial assets shall not be reclassified after initial confirmation.

     Financial assets are measured at fair value on initial recognition. The relevant transaction cost of financial
     assets at fair value through profit or loss is directly recognised in profit or loss for the current period, and that
     of other types of financial assets is included in the initially recognised amount. Trade receivables or notes
     receivable arising from sales of goods or rendering services, without significant financing component, are
     initially recognised based on the transaction price expected to be entitled by the Company.

(3) Classification and measurement of financial liabilities

     On initial recognition, the Company's financial liabilities are classified into financial liabilities at fair value
     through profit or loss and financial liabilities at amortised cost. For financial liabilities not classified as
     financial liabilities at fair value through profit or loss, the relevant transaction costs are included in the
     initially recognised amount.

     Financial liabilities at fair value through profit or loss

     Financial liabilities at fair value through profit or loss include financial liabilities held for trading and
     financial liabilities designated at fair value through profit or loss upon initial recognition. Such financial
     liabilities are subsequently measured at fair value, all gains and losses arising from changes in fair value and
     dividend and interest expense relative to the financial liabilities are recognised in profit or loss for the current
     period.

     Financial liabilities at amortised cost

     Other financial liabilities are subsequently measured at amortised cost using the effective interest method;
     gains and losses arising from derecognition or amortisation is recognised in profit or loss for the current
     period.



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     Joincare Pharmaceutical Group                                                                     Annual Report 2022


     Distinction between financial liabilities and equity instruments

     The financial liability is the liability that meets one of following criteria:

     ① Contractual obligation to deliver cash or other financial instruments to another entity.

     ② Under potential adverse condition, contractual obligation to exchange financial assets or financial
     liabilities with other parties.

     ③ A contract that will or may be settled in the entity's own equity instruments and is a non-derivative for
     which the entity is or may be obliged to deliver a variable number of the entity's own equity instruments.

     ④ A derivative that will or may be settled other than by the exchange of a fixed amount of cash or another
     financial asset for a fixed number of the entity's own equity instruments.

     An equity instrument is any contract that evidences a residual interest in the assets of an entity after deducting
     all of its liabilities.

     If the Company cannot unconditionally avoid fulfilling a contractual obligation by delivering cash or other
     financial assets, the contractual obligation meets the definition of financial liability.

     If a financial instrument must or are able to be settled by the Company's own equity instrument, the Company
     should consider whether the Company's equity instrument as the settlement instrument is a substitute of cash
     or other financial assets or the residual interest in the assets of the Company after deducting all of its liabilities.
     If the former, the tool is the Company's financial liability; if the latter, the tool is the equity instrument of the
     Company.

(4) Derivative financial instruments and embedded derivatives

     The Company's derivative financial instruments include forward foreign exchange contracts, and are initially
     measured at fair value on the date of the derivative contract signed and are subsequently measured at fair
     value. A derivative with positive fair value shall be recognised as an asset, otherwise that with negative fair
     value shall be recognised as a liability. Any profit or loss arising from changes of fair value and not
     compliance with the accounting provision of hedge shall be recognised as profit or loss for current period.

     For the hybrid instrument which includes embedded derivatives, where the host contract is a financial asset,
     requirements in relation to the classification of financial assets shall apply to the hybrid instrument as a whole.
     Where the host contract is not a financial asset, and the hybrid instrument is not measured at fair value and
     its changes are included in the profit and loss for the current period for accounting purposes, there is no close
     relation between the embedded derivatives and the host contract in terms of economic features and risks, and
     the instrument that has the same condition with the embedded derivatives and exists independently meets the
     definition of derivatives, the embedded derivatives shall be separated from the hybrid instrument and treated
     as a separate derivative financial instrument. If it is unable to separately measure the embedded derivatives
     upon acquisition or on the subsequent balance sheet date, the hybrid instrument shall be entirely designated
     as the financial assets or financial liabilities measured at fair value and whose movements are included in the
     profit and loss of the current period.

(5) Fair value of the financial instrument

     The methods for determining the fair value of the financial assets or financial liabilities are set out in Note
     III.11.

(6) Impairment of financial assets

     The following items are subject to impairment accounting and recognition of loss allowances based on
     expected credit losses:

     A. Financial assets measured at amortised cost;


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Joincare Pharmaceutical Group                                                                 Annual Report 2022


B. Receivables and debt investments that are measured at fair value through other comprehensive income;

C. Contract assets as defined in the Accounting Standard for Business Enterprises No. 14 – Revenue;

D. Lease receivables;

E. Financial guarantee contracts, except for those carried at fair value through profit or loss, those which the
transfer of financial assets does not satisfy the derecognition condition or those formed as a result of
continued involvement of the transferred financial assets.

Measurement of expected credit loss (ECLs)

The ECL is a weighted average of credit losses on financial instruments weighted at the risk of default. Credit
loss is the difference between all receivable contractual cash flows according to the contract and all cash
flows expected to be received by the Company discounted to present value at the original effective interest
rate, i.e. the present value of all cash shortfalls.

The Company takes into account reasonable and valid information on past events, current conditions and
forecasts of future economic conditions, with the risk of default as the weight, to calculate the probabilistic
weighted amount of the present value of the difference between the cash flow receivable from contract and
the expected cash flow to be received and recognise the expected credit loss.

The Company respectively measures the expected credit losses of financial instruments by different stages.
If the credit risk of the financial instrument does not increase significantly since the initial recognition, it
would be classified in Stage 1, the Company would measure loss allowance according to the future 12-month
expected credit losses. If the credit risk of a financial instrument has significantly increased since the initial
recognition but not yet credit-impaired, it would be classified in Stage 2, the Company would measure loss
allowance according to the lifetime expected credit losses of that instrument. If the financial instrument has
credit-impaired since the initial recognition, it would be classified in Stage 3, and the Company would
measure loss allowance according to the lifetime expected credit losses of that instrument.

For financial instruments with lower credit risk on the balance sheet date, the Company assumes that its
credit risk has not increased significantly since the initial recognition, and measures loss allowance according
to the 12-month expected credit losses.

Lifetime ECLs are the ECLs that result from all possible default event over the expected life of a financial
instrument. Future 12-month ECLs are the portion of ECL that results from default events on a financial
instrument that are possible within the 12 months after the balance sheet date (or the expected life of the
instrument, if it is less than 12 months).

The maximum period considered when estimating ECLs is the maximum contractual period over which the
Company are exposed to credit risk (including the option to renew).

For the financial instruments classified in Stage 1 and Stage 2 and those with lower credit risk, the Company
would measure the interest income by the book balance (that is, without deduction for credit allowance) and
the effective interest rate. For financial instruments classified in Stage 3, the Company would measure the
interest income by the amortised cost (that is, book balance less impairment allowance) and the effective
interest rate.

For notes receivable, trade receivables and contract assets, regardless whether it has significant financing
components or not, the Company has always measured its loss allowance at an amount equal to lifetime
expected credit losses.

If the expected credit losses of one individual financial asset cannot be estimated at a reasonable cost, the
Company classifies notes receivable and trade receivables into portfolios based on credit risk characteristics,
and measures expected credit losses on portfolios basis to determine portfolios by the following basis:

A. Notes receivable


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Joincare Pharmaceutical Group                                                                Annual Report 2022


   Bills receivable portfolio 1: Bank acceptance bills

   Bills receivable portfolio 2: Commercial acceptance bills

B. Accounts receivables

   Accounts receivables portfolio 1: Amount due from domestic customers

   Accounts receivables portfolio 2: Amount due from overseas customers

   Accounts receivables portfolio 3: Receivables of consolidated companies

Contract assets

   Contract assets portfolio: Sale of products

For bills receivable classified as portfolio, the Company measures expected credit losses based on the risk
exposures of default and lifetime expected credit losses rate with reference to the historical credit loss
experience, current situation and forecasts of future economic conditions.

For accounts receivables classified as portfolio, the Company measures expected credit losses through
preparing a table of concordance between the aging of trade receivables and lifetime expected credit losses
rate with reference to the historical credit loss experience, current situation and forecasts of future economic
conditions.

Other receivables

The Company classifies other receivables into certain portfolios based on credit risk characteristics, and
measures expected credit losses on portfolios basis to determine portfolios by the following basis:

   Other receivables portfolio 1: Receivables of export tax refund

   Other receivables portfolio 2: Receivables of deposits under guarantee and security deposits and lease
   expenses

   Other receivables portfolio 3: Other receivables

   Other receivables portfolio 4: Receivables of consolidated companies

For other receivables classified as portfolio, the Company measures expected credit losses based on the risk
exposures of default and future 12-month or lifetime expected credit losses rate.

Long-term receivables

The Company's long-term receivables include finance lease receivables and equity transfer receivables.

The Company classifies finance lease receivables and equity transfer receivables into certain portfolios based
on credit risk characteristics, and measures expected credit losses on portfolios basis to determine portfolios
by the following basis:

A. Finance lease receivables

   Portfolio of finance lease receivables: other receivables

B. Other long-term receivables

   Portfolio of other long-term receivables: equity transfer receivables

For finance lease receivables and equity transfer receivables, the Company measures expected credit losses
based on the risk exposures of default and lifetime expected credit losses rate with reference to the historical

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Joincare Pharmaceutical Group                                                                Annual Report 2022


credit loss experience, current situation and forecasts of future economic conditions.

For other receivables and long-term receivables other than finance lease receivables and equity transfer
receivables that are classified as portfolio, the Company measures expected credit losses based on the risk
exposures of default and future 12-month or lifetime expected credit losses rate.

Debt investments and other debt investments

For debt investments and other debt investments, the Company measures expected credit losses based on the
nature of investments, counterparties and various types of risk exposures and the risk exposures of default
and future 12-month or lifetime expected credit losses rate.

Assessment of significant increase in credit risk

By comparing the risk of default of financial instruments occurring on the balance sheet date and on the
initial recognition date, the Company determines the relative changes in risk of default over the expected life
of financial instruments and assesses whether the credit risk of financial instruments have increased
significantly since the initial recognition.

When determine whether credit risks have significantly increased since the initial recognition, the Company
considers information that is reasonable and supportable, including forward-looking information that is
available without undue cost or effort. The information considered by the Company includes:

   Failure to make payments of principal or interest on debtors' contractually due dates;

   An actual or expected significant deterioration in a financial instrument's external or internal credit
   rating (if any);

   An actual or expected significant deterioration in the operating results of debtors;

   Existing or forecast changes in the technological, market, economic or legal environment that have
   significant adverse effect on the debtors' abilities to repay to the Company.

Depending on the nature of the financial instruments, the Company assesses whether credit risks have
significantly increased on either an individual financial instrument basis or a collective financial instrument
basis. When the assessment is performed on a collective financial instrument basis, the Company can classify
the financial instruments based on the shared credit risk characteristics, such as past due information and
credit risk ratings.

The Company determines that the credit risk on a financial instrument has increased significantly if it is more
than 30 days past due.

Credit-impaired financial assets

The Company assesses whether financial assets at amortised cost and debt investments measured at fair value
through other comprehensive income are credit-impaired at balance sheet date. A financial asset is “credit-
impaired” when one or more events that have an adverse impact on the estimated future cash flows of the
financial asset have occurred. Evidence that a financial asset is credit-impaired includes the following
observable information:

   Significant financial difficulty of the issuer or debtor;

   A breach of contract by debtor, such as a default or delinquency in interest or principal payments;

   For economic or contractual reasons relating to the borrower's financial difficulty, the Company having
   granted to the borrower a concession that would not otherwise consider;

   It is probable that the borrower will enter bankruptcy or other financial reorganization;


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      Joincare Pharmaceutical Group                                                                     Annual Report 2022


         The disappearance of an active market for that financial asset because of financial difficulties.

      Presentation of allowance for ECL

      The Company re-measures the ECLs on each balance sheet date to reflect changes in the financial
      instruments' credit risk since initial recognition, and the increase or reversal of the loss provision resulted
      therefrom is recognised as an impairment gain or loss in profit or loss. For financial assets measured at
      amortised cost, the loss provision is offset against their carrying amounts in the balance sheet. For debt
      investments at FVOCI, the Company recognises the loss provision in other comprehensive income and does
      not deduct the carrying amount of the financial assets.

      Write-off

      The gross carrying amount of a financial asset is written off (either partially or in full) to the extent that there
      is no realistic prospect of recovery. A write-off constitutes a derecognition event. This is generally the case
      the Company determines that the debtor does not have assets or sources of income that could generate
      sufficient cash flows to repay the amounts subject to the write-off. However, financial assets that are written
      off could still be subject to enforcement activities in order to comply with the Company's procedures for
      recovery of amounts due.

      Subsequent recoveries of an asset that was previously written off are recognised as a reversal of impairment
      in profit or loss in the period in which the recovery occurs.

(7) Transfer of financial assets

      Transfer of financial assets refers to the transfer or delivery of financial assets to the other party (the transferee)
      other than the issuer of financial assets.

      The Company derecognises a financial asset only if it transfers substantially all the risks and rewards of
      ownership of the financial asset to the transferee; the Company should not derecognise a financial asset if it
      retains substantially all the risks and rewards of ownership of the financial asset.

      The Company neither transfers nor retains substantially all the risks and rewards of ownership, shows as the
      following circumstances: if the Company has forgone control over the financial assets, derecognise the
      financial assets and verify the assets and liabilities; if the Company retains its control of the financial asset,
      the financial asset is recognised to the extent of its continuing involvement in the transferred financial asset
      and recognise an associated liability is recognised.

(8) Offsetting financial assets and financial liabilities

      When the Company has the legal right to offset recognised financial assets and financial liabilities, and the
      legal right can be executed at present, and the Company has a plan to settle the financial assets and financial
      liabilities at the same time or at net amount, the financial assets and financial liabilities can be presented on
      the balance sheet after offsetting. Except for the above circumstances, financial assets and financial liabilities
      cannot be offset and shall be presented separately on the balance sheet.

11. Fair value measurement

      The fair value is defined as the price that would be received to sell an asset or paid to transfer a liability in
      an orderly transaction between market participants at the measurement date.

      The Company measures the relevant assets or liability at fair value supposing the orderly transaction of asset
      selling or liability transferring incurring in a principal market of relevant assets or liabilities. In the absence
      of a principal market for the asset or liability, the Company assumes that the transaction takes place at the
      most advantageous market of relevant asset or liability. A principal market (or the most advantageous market)
      is the transaction market that the Company can enter into at measurement date. The Company implements
      the hypothesis used by the market participants to realise the maximum economic benefit in assets or liabilities
      pricing.


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     Joincare Pharmaceutical Group                                                                 Annual Report 2022


     If there exists an active market for the financial assets or financial liabilities, the Company uses the quotation
     on the active market as its fair value. For those in the absence of active market, the Company uses valuation
     technique to recognise its fair value. However, under limited circumstances, the Company may use all
     information about the results and operation of the investee obtained after the date of initial recognition to
     determine whether cost represents fair value. Cost may represent the best estimate of fair value of the relevant
     financial asset within the scope of distribution, and such cost represents the appropriate estimate of fair value
     within the scope of distribution.

     For non-financial assets measured at fair value, the Company should consider the capacity of the market
     participants to put the assets into optimal use thus generating the economic benefit, or the capacity to sell
     assets to other market participants who can put the assets into optimal use and generate economic benefit.

     The Company implements the valuation technique suitable for the current condition and supported by enough
     available data and other information, gives priority in use of relevant observable inputs, only the observable
     inputs cannot be obtained or impracticable before using unobservable inputs.

     For the assets and liabilities measured or disclosed at fair value on financial statements, fair value hierarchies
     are categorized into three levels as the lowest level input that is significant to the entire fair value
     measurement: Level 1: inputs are quoted prices (unadjusted) in active markets for identical assets and
     liabilities. Level 2: inputs are inputs other than quoted prices included within Level 1 that are observable for
     the asset or liability, either directly or indirectly. Level 3: inputs are unobservable inputs for the asset or
     liability.

     At each balance sheet date, the Company re-evaluates the assets and liabilities recognised to be measured at
     fair value on the financial statements to make sure whether conversion occurs between fair value hierarchies.

12. Inventories

(1) Classification of inventories

     The Company's inventories include raw materials, packaging materials, finished goods, work-in-progress,
     low-value consumables, subcontracting materials, inventory goods, expendable biological assets and goods
     in transit.

(2) Method of costing

     The method of costing of the Company's inventories: Cost of finished goods are measured at planned cost,
     and material cost differences are carried forward at the end of the period to adjust planned cost to actual cost;
     other inventories are measured at actual cost on acquisition and raw materials received are accounted for by
     the weighted-average method; low-value consumables and packaging materials are amortised in full upon
     the use.

(3) Method in the determination and the basis of provision for diminution in net realisable value of inventories

     On the balance sheet date, the inventories are calculated at the lower of cost and the net realisable value.
     When the net realisable value is lower than the cost, the provision for diminution in value of inventories is
     made on an item-by-item basis at the excess of the cost of the inventory over its net realisable value. For
     large volume inventories with low unit price, the provision for diminution in the value of inventories is made
     by categories. Inventories that are related to a product line manufactured and sold in the same region, have
     the same or similar end use or purpose, and are difficult to measure separately from other items are
     consolidated the provision for diminution in the value of inventories.

(4) Inventory system

     The Company maintains a perpetual inventory system.

(5) Amortisation methods of consumables and packaging materials

     Low-value consumables and packaging materials of the Company are amortised in full when used.

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     Joincare Pharmaceutical Group                                                                    Annual Report 2022


13. Held for sale and discontinued operations

(1) Category and measurement of non-current assets or the disposal group held for sale

     Non-current assets and disposal groups are classified as held for sale if the Company recovers its book value
     mainly by selling (including the exchange of nonmonetary assets with commercial substance) rather than
     continuing to use it.

     The aforesaid non-current assets do not include investment property measured with the basis of fair value;
     the biological assets measured with the basis of fair value less selling costs; the assets formed by employee
     benefits; financial assets and the right arising from deferred income tax assets and insurance contracts.

     A disposal group is a group of assets to be disposed through sale or other means as a whole in a single
     transaction, and liabilities directly associated with those assets that will be transferred in the transaction. In
     certain circumstance, disposal groups include the goodwill obtained through business combination.

     Non-current assets and disposal groups that meet the following conditions are classified as held for sale:
     according to the practice of disposing of this type of assets or disposal groups in a similar transaction, a non-
     current asset or disposal group is available for immediate sale at its present condition; the sale is likely to
     occur, that is, a decision has been made on a sale plan and a determined purchase commitment is made, and
     the sale is expected to be completed within one year. Where the loss of control over the subsidiaries is due to
     the sales of investment in subsidiaries, no matter whether the Company retains part of the equity investment
     after selling or not, the investment in subsidiaries shall be classified as held for sale in the separate financial
     statements when it satisfies the conditions for category of held for sale; all assets and liabilities of subsidiaries
     shall be classified as held for sale in the consolidated financial statements.

     The difference between carrying amount of non-current assets or disposal groups classified as held for sale
     and the net amount of fair value less selling costs shall be recognised as impairment loss on assets upon initial
     measurement or when such non-current assets or disposal groups are remeasured at the balance sheet date.
     For the amount of impairment loss on assets recognised in disposal groups, the carrying amount of disposal
     groups' goodwill shall be offset against first, and then offset against the carrying amount of non-current assets
     according to the proportion of carrying amount of the individual non-current assets in the disposal groups.

     If on a subsequent balance sheet date, the net amount of the fair value of a held-for-sale disposal group less
     its selling costs increases, the amount reduced previously shall be recovered, and reversed in the asset
     impairment loss recognised on the noncurrent asset which is applicable to the measurement requirements of
     Held-For-Sale Standards after the non-current asset is classified into held-for-sale category. The reversed
     amount is credited to current profit or loss. The carrying value of goodwill which has been offset cannot be
     reversed.

     No depreciation or amortisation is provided for the non-current assets in the held-for-sale and the assets in
     the disposal group held for sale. The interest on the liabilities and other costs in the disposal group held for
     sale is recognised continuously. As far as all or part of investment in the associates and joint ventures is
     concerned, for the part classified into the held-for-sale category, the accounting with equity method shall be
     stopped, while the remaining part (which is not classified into the held for- sale category) shall still be
     accounted for using the equity method. When the Company loses the significant influence on the associates
     and joint venture due to the sale, the use of equity method shall be ceased.

     When certain non-current asset or disposal group classified into the held-for-sale category no longer meets
     the classification criteria for held-for-sale category, the Company shall stop classifying it into the held-for-
     sale category and measure it according to the lower of the following two amounts:

     ① The carrying amount of the asset of disposal group before it was classified into the held-for-sale category
     after being adjusted with the depreciation, amortisation or impairment that could have been be recognised if
     it was not classified into the held-for-sale category;

     ② The recoverable amount.



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     Joincare Pharmaceutical Group                                                                       Annual Report 2022


(2) Discontinued operation

     Discontinued operation refers to the component meeting one of the following conditions that has been
     disposed of by the Company or classified by the Company into the held-for-sale type and can be identified
     separately:

     ① The component represents an independent principal business or a separate principal business place.

     ② The component is a part of the related plan for the contemplated disposal of an independent principal
     business or a separate principal business place.

     ③ The component is a subsidiary acquired exclusively for the purpose of resale.

(3) Presentation

     The Company presents the non-current assets held for sale and the assets in the disposal group held for sale
     under “assets classified as held for sale”, and the liabilities in the disposal group held for sale under “liabilities
     classified as held for sale” in the balance sheet.

     The Company presents the profit and loss for continuing operation and profit and loss for discontinued
     operation in the income statement, respectively. The impairment loss and reversal amount and disposal profit
     and loss of the non-current assets held for sale or disposal group not meeting the definition of discontinued
     operation will be presented as the profit and loss of continuing operation. The operating profit and loss (such
     as impairment loss and reversal amount) and disposal profit and loss of the discontinued operation will be
     presented as the profit and loss of the discontinued operation.

     The disposal group proposed for retirement rather than sale and meeting the condition about the relevant
     component in the definition of the discontinued operation will be presented as discontinued operation from
     the date of retirement.

     For the discontinued operation reported in the current period, the information formerly presented as profit
     and loss of continuing operation will be presented as the profit and loss of discontinued operation for the
     comparable accounting period in the financial statement of the current period. If the discontinued operation
     no longer meets the classification criteria for held-for-sale category, the information formerly presented as
     profit and loss of discontinued operation will be presented as the profit and loss of continuing operation for
     the comparable accounting period in the financial statement of the current period.

14. Long-term equity investment

     The long-term equity investment includes the equity investment in the subsidiary, joint ventures and
     associates. The investee over which the Company has significant influence is the associates of the Company.

(1) Determination of initial investment cost

     The long-term equity investment resulting from corporate merger: For the long-term equity investment
     resulting from merger of companies under the same control, the carrying amount of the ownership equity of
     the merged party obtained on the merger date presented in the consolidated financial statement of the final
     controlling party will be used as the investment cost. For the long-term equity investment resulting from
     merger of companies under different controls, the merger cost will be used as the investment cost of the long-
     term equity investment.

     The long-term equity investment obtained by other means: For the long-term equity investment obtained by
     paying cash, the actually paid purchase price will be used as the initial investment cost. For the long term
     equity investment obtained by issuing equity securities, the fair value of the issued equity securities will be
     used as the initial investment cost.

(2) Subsequent measurement and recognition method of profit or loss



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Joincare Pharmaceutical Group                                                                 Annual Report 2022


The investment in subsidiary will be accounted for using cost method, unless the investment meets the criteria
of held-for-sale category. The investment in associates and joint venture will be accounted with equity
method.

For the long-term equity investment accounted for using cost method, except for the price actually paid upon
the investment or the cash dividend or profit in the consideration that has been declared but not released, the
cash dividend or profit declared and distributed by the investee is recognised as the investment income and
recorded into the profit and loss for the current period.

For the long-term equity investment accounted for using equity method, the investment cost of the long-term
equity investment shall not be adjusted if the initial investment cost of the long-term equity investment is
higher than the Company's share in the fair value of the identifiable net value of the investee at the time of
investment; if the initial investment cost of the long-term equity investment is lower than the Company's
share in the fair value of the identifiable net value of the investee at the time of investment, the carrying
amount of the long-term equity investment will be adjusted, with the difference recorded into the profit and
loss for the current period of investment.

When accounted for using the equity method, return on investment and other comprehensive income are
recognised according to the share in the investee's realised net profit or loss and other comprehensive income
respectively, and the carrying amount of the long-term equity investment is adjusted. The carrying amount
of the long-term equity investment will be deducted according to the profit distribution declared by the
investee or cash dividend attributable to the Company. The carrying amount of long term equity investment
will be adjusted for changes to equity interest attributable to the owners of the investee other than net profit
or loss, other comprehensive income and profit distribution, and recorded into capital reserve (other capital
reserve). The Company's share of the net profit or loss of the investees will be recognised after adjustment
of the net profit of the investees according to the accounting policy and accounting period of the Company
on the basis of fair value of all identifiable assets of the investee on acquisition.

If the Company is able to exert significant influence or implement joint control (which does not constitute
control) on the investee through additional investment or other reason, the sum of the fair value of the original
equity plus the additional investment cost will be used as the initial investment cost, which will be accounted
for with equity method, on the conversion date. The difference between the fair value of the original equity
on the conversion date and its carrying amount, and the accumulated change of fair value recorded into other
comprehensive income will be transferred into the profit and loss for the current period, which will be
accounted for using equity method.

If an entity loses joint control or has no significant influence over investees due to the elimination of parts of
the equity investment, the surplus equity after disposal shall be recognised in accordance with “Accounting
Standards for Business Enterprises No. 22 – Recognition and Measurement of Financial Instruments”, and
the difference between fair value and carrying amount should be recognised as profit or loss for current period.
Other comprehensive income of original equity investment recognised under equity method shall be
recognised in accordance with the same foundation used by the investees when dispose the relevant assets or
liabilities directly in the termination of equity method. Other changes of owners' equity related to the original
equity investment shall be transferred into profit or loss for current period.

If an entity loses control over investees due to the elimination of parts of the equity investment, the surplus
owners' equity that is able to implement joint control or have significant influence over investees shall be
measured at equity method and are deemed to be recognised under equity method since the acquisition date.
The surplus owners' equity that are unable to implement joint control or have no significant influence over
investees shall be processed in accordance with “Accounting Standards for Business Enterprises No. 22 –
Recognition and Measurement of Financial Instruments”, and the difference between fair value and carrying
amount at the day of loss of control shall be recognised as profit or loss for current period.

If the shareholding ratio of the Company is reduced due to the increase of capital of other investors, and thus
the control is lost, but the joint control or significant influence can be exerted on the invested entity, the
Company should recognise net asset according to the new shareholding ratio. The difference between the
original book value of the long-term equity investment corresponding to the decrease in the shareholding
ratio should be included in the current profit and loss; then, according to the new shareholding ratio, the

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     Joincare Pharmaceutical Group                                                                 Annual Report 2022


     equity method is used to adjust the investment.

     The Company recognises the unrealised profit or loss of intra-transaction between the joint ventures or
     associates that belongs to itself according to the proportion of the shares and recognises the investment
     income or loss after offset. However, the loss arising from the unrealised intra-transaction between the
     Company and investees, which belongs to the impairment loss of assets transferred, cannot be offset.

(3) Basis of determining common control and significant influence on the investee

     Joint control is the contractually agreed sharing of control over an arrangement under which the decisions
     relating to any activity require the unanimous consent of the parties sharing control. In determining whether
     there is a joint control, the first judge is to determine whether the relevant arrangement is controlled
     collectively by all the parties involved or the group of the parties involved. Secondly, and then determine
     whether the decisions related to the basic operating activities should require the unanimous consent of the
     parties involved. If the parties involved or the group of the parties involved must act consistently to determine
     the relevant arrangement, it is considered that the parties involved or the group of the parties involved control
     the arrangement. If two or more parties involve in the collectively control of certain arrangement, it shall not
     be considered as joint control. Protection of rights shall not be considered in determining whether there is
     joint control.

     Significant influence refers to the power to participate in the decision making process for financial and
     operational policies of the investees without control or common control over the formulation of such policies.
     When determining whether it has significant influence over the investee, the influence of the voting shares
     of the investee held by the investor directly and indirectly and the potential voting rights held by the investor
     and other parties which are exercisable in the current period and converted to the equity of the investee,
     including the warrants, stock options and convertible bonds that are issued by the investee and can be
     converted in the current period, shall be taken into account.

     When the Company owns directly or indirectly through its subsidiaries more than 20% (including 20%) but
     less than 50% of the voting shares of the investee, it is generally considered to have significant influence
     over the investee, unless there is clear evidence that it cannot participate in the production and operation
     decisions of the investee and does not have a significant influence under such circumstances. When the
     Company owns less than 20% (excluding) of the voting shares of the investee, it is generally not considered
     to have significant influence on the investee unless there is clear evidence that it can participate in the
     production and operation decisions of the investee and have significant influence under such circumstances.

(4) Held-for-sale equity investment

     Refer to Note III. 13 for the relevant accounting treatment of the equity investment to joint ventures or
     associates all or partially classified as assets held for sale.

     The surplus equity investments that are not classified as assets held for sale shall be accounted for using
     equity method.

     The equity investment to joint ventures or associates already classified as held for sale no longer meets the
     conditions of assets held for sale shall be adjusted retroactively using equity method from the date of being
     classified as assets held for sale.

(5) Impairment test and impairment provision

     Refer to note III. 22 for investment to subsidiaries, associates and joint ventures and the impairment provision
     of assets.

15. Investment properties

     Investment properties are properties held to earn rental or capital appreciation or both. The investment
     properties of the Company include land use rights that have already been leased out, land use rights that are
     held for the purpose of sale after capital appreciation, buildings that have already been leased out, etc.


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     Joincare Pharmaceutical Group                                                                Annual Report 2022


     Investment properties of the Company are measured initially at cost upon acquisition, and subject to
     depreciation or amortisation in the relevant periods according to the relevant provisions on fixed assets or
     intangible assets.

     The Company adopts the cost model for subsequent measurement of the investment properties. The method
     for asset impairment provision is set out in note III. 22.

     The balance after the disposal income from the disposal, transfer, scrapping or destruction of the investment
     properties deducts the book value and the relevant taxes shall be recorded into the profit and loss for the
     current period.

16. Fixed asset

(1) Conditions for recognition of fixed assets

     The Company's fixed assets represent the tangible assets held by the Company using in the production of
     goods, rendering of services, rent and for operation and administrative purposes with useful life over one
     year.

     The fixed asset can be recognised only when the economic benefit related to the fixed asset is probable to
     flow into the company and the cost of the fixed asset can be reliably measured.

     The Company's fixed assets are initially measured at the actual cost at the time of acquisition.

(2) Method of depreciation

     The Company adopts the straight-line method to provision for depreciation. Depreciation of fixed assets
     begins when they reach the status of intended use, and ceases to be depreciated when they are derecognized
     or classified as non-current assets held for sale. Without taking into account the provision for impairment,
     the Company determines the annual depreciation rates of various types of fixed assets according to the type
     of fixed assets, estimated useful life and estimated residual value as follows:

      Category                              Useful years (year)         Annual depreciation          Residual rate %
      Properties and Buildings                      20                      4.5%-4.75%                  5%-10%
      Machine and equipment                         10                       9%-9.5%                    5%-10%
      Transportation equipment                      5                       18%-19%                     5%-10%
      Electric equipment and others                5-10                     18%-19%                     5%-10%

     Where, for the fixed assets for which depreciation provision is made, to determine the depreciation rate, the
     accumulated amount of the fixed asset depreciation provision that has been made shall be deducted.

(3) Refer to note III. 22 for the impairment testing and the impairment provision of fixed assets.

(4) Recognition basis, valuation and depreciation method of financial leased fixed assets

     When the Company's leased fixed assets meet one or more of the following criteria, it is recognized as finance
     leased fixed assets:

     ① At the expiration of the lease term, the ownership of the leased assets is transferred to the Company.

     ② The Company has the option to purchase leased assets. The agreed purchase price is expected to be much
     lower than the fair value of the leased asset when the option is exercised. Therefore, it can be reasonably
     determined that the Company will exercise this option on the lease start date.

     ③ Even if the ownership of the asset is not transferred, the lease term occupies most of the useful life of the
     leased asset.


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     Joincare Pharmaceutical Group                                                                  Annual Report 2022


     ④ The present value of the Company's minimum lease payment on the lease start date is almost equivalent
     to the fair value of the leased assets on the lease start date.

     ⑤The leased assets are of special nature, and only our company can use them if they don't undergo major
     transformation.

     For fixed assets leased by finance leases, the lower of the fair value of the leased assets on the lease start date
     and the present value of the minimum lease payment shall be the entry value. The minimum lease payment
     is taken as the entry value of the long-term payable, and the difference is taken as the unrecognized financing
     expense. In the process of lease negotiation and signing of the lease contract, the initial direct costs
     attributable to the lease item, such as handling fees, attorney fees, travel expenses, stamp duty, etc., are
     included in the value of the leased asset. The unrecognized financing costs shall be amortized by the effective
     interest method during each period of the lease term.

     The fixed assets acquired by finance lease adopt the same policy as self-owned fixed assets to calculate the
     depreciation of leased assets. If it can be reasonably determined that the ownership of the leased asset will
     be obtained at the end of the lease term, depreciation shall be accrued on the useful life of the leased asset; if
     it cannot be reasonably determined that the ownership of the leased asset will be obtained at the end of the
     lease term, depreciation is accrued in the shorter of the lease period and the useful life of the leased asset.

(5) The Company reviews the useful life and estimated net residual value of fixed asset and the depreciation method
     applied annually at each of the period end.

     The useful lives of fixed asset are adjusted if their expected useful lives are different from the original
     estimates; the estimated net residual values are adjusted if they are different from the original estimates.

(6) Overhaul costs

     The overhaul costs occurred in regular inspection of f are recognised in the cost of property, plant and
     equipment if there is undoubted evidence to confirm that they meet the recognition criteria of fixed assets,
     otherwise, the overhaul costs are recognised in profit or loss for the current period. Property, plant and
     equipment are depreciated during the intervals of the regular overhaul.

17. Construction in progress

     Construction in progress is measured at actual cost. Actual cost comprises necessary project expenditure
     incurred during construction, borrowing cost that are eligible for capitalisation and other necessary cost
     incurred to bring the fixed assets ready for their intended use.

     Construction in progress is transferred to fixed assets when the assets are ready for their intended use.

     For provision for impairment of construction in progress, refer to note III. 22.

     In the balance sheet, the ending balance of construction materials is presented under “construction in
     progress”.

18. Borrowing costs

(1) Recognition principle of capitalisation of borrowing costs

     For borrowing costs that are directly attributable to the acquisition, construction or production of a qualifying
     asset, they shall be capitalised and included in the cost of related assets; other borrowing costs are recognised
     as expenses and included in profit or loss when incurred. Capitalisation of such borrowing costs can
     commence only when all of the following conditions are satisfied:

     ① Expenditures for the asset incurred, capital expenditure includes the expenditure in the form of cash
     payment, transfer of non-cash assets or the interest bearing liabilities for the purpose of acquiring or
     constructing assets eligible for capitalisation;


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      Joincare Pharmaceutical Group                                                                 Annual Report 2022


      ② Borrowing costs incurred;

      ③ Activities relating to the acquisition, construction or production of the asset that are necessary to prepare
      the asset for its intended use or sale have commenced.

(2) Capitalisation period of borrowing costs

      Capitalisation of such borrowing costs ceases when the qualifying assets being acquired, constructed or
      produced become ready for their intended use or sale. The borrowing cost incurred after that is recognised as
      an expense in the period in which they are incurred and included in profit or loss for the current period.

      Capitalisation of borrowing costs is suspended during periods in which the acquisition, construction or
      production of a qualifying asset is interrupted abnormally and when the interruption is for a continuous period
      of more than 3 months; the borrowing costs in the normally interrupted period continue to capitalise.

(3) Calculation of the capitalisation rate and amount of borrowing costs

      The interest expense of the specific borrowings incurred at the current period, deducting any interest income
      earned from depositing the unused specific borrowings in bank or the investment income arising from
      temporary investment, shall be capitalised. The capitalisation rate of the general borrowing is determined by
      applying the weighted average effective interest rate of general borrowings, to the weighted average of the
      excess amount of cumulative expenditures on the asset over the amount of specific borrowings.

      During the capitalisation period, exchange differences on foreign currency special borrowings shall be
      capitalised; exchange differences on foreign currency special borrowings shall be recognised as current
      profits or losses.

19. Biological assets

(1) Determination of biological assets

      Biological assets refer to assets comprising living animals and plants. No biological asset shall be recognised
      unless it meets the conditions as follows simultaneously:

      ① An enterprise possesses or controls the biological asset as a result of past transaction or event;

      ② The economic benefits or service potential concerning this biological asset are likely to flow into the
      enterprise;

      ③ The cost of this biological asset can be measured reliably.

(2) Classification of biological assets

      The Company’s biological assets are consumable biological assets which include traditional Chinese medical
      herbal plant species.

      The consumable biological assets refer to the biological assets held for sale, or biological assets to be
      harvested as agricultural products in the future, consisting of growing traditional Chinese medical herbal
      plant species. The consumable biological asset is initially measured at cost. The cost of any consumable
      biological assets by way of self-planting, self-cultivating, self-breading is the necessary cost directly
      attributable to this asset prior to the harvest, consisting of borrowing costs that meet the conditions of
      capitalisation. The subsequent expenses for the maintenance, protection and cultivation of a consumable
      biological asset after the harvest shall be included in the current profits or loss.

      The cost of a consumable biological asset shall, at the time of harvest or sale, be carried over at its book value
      by the weighted average method.

(3) Impairment of biological assets


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     Joincare Pharmaceutical Group                                                                    Annual Report 2022


     If the net realisable value of the consumable biological assets is lower than their carrying amount, provision
     of impairment loss is made and recognised in the profit or loss for the current period as the excess of the
     carrying amount over the net realisable value. If the factors affecting the impairment of consumable
     biological assets no longer exist, the amount of write-down shall be resumed and shall be reversed from the
     original provision for the impairment loss before being recognised in the profit or loss for the current period.

20. Intangible assets

     An intangible asset is an identifiable non-monetary asset without physical substance owned or controlled by
     the Company. An intangible asset is recognised only when all of the following conditions are satisfied: It is
     probable that the economic benefits associated with the intangible assets will flow to the enterprise; The cost
     of the intangible asset can be reliably measured. Intangible assets are initially measured at actual cost.

     The Company's intangible assets include land use rights, patents and proprietary technologies, software,
     trademark rights, etc.

     Intangible assets are initially measured at historical cost, and the Company shall make judgement to
     determine the useful life of intangible assets upon acquisition. Intangible assets with finite useful life are
     amortised in the profit or loss over the estimated useful life, using the method that reflects the expected
     realisation of economic benefits associated with the asset, and if the expected realisation cannot be reliably
     determined, it is amortised using the straight-line method. Intangible assets with indefinite useful life is not
     amortised.

     Amortisation of intangible assets with finite useful life is as follows:

      Category                                   Expected useful life             Amortization method          Note

      Land use rights                                     30-50 years                       Straight-line

      Patent and technical know-how                         1-10 years                      Straight-line

      Software                                              2-10 years                      Straight-line

      Trademark rights                                         5 years                      Straight-line

      Others                                                 10 years                       Straight-line




     The useful life for an intangible asset with a finite useful life and the method of amortisation are reviewed at
     least once at the end of each financial year. If the useful life and amortisation method for the intangible assets
     are different from the previous estimate, the change of amortisation is recognised prospectively as the change
     of accounting estimate.

     When the Company estimates an intangible asset can no longer bring future economic benefits to the
     Company at the end of a period, the carrying amount in which should be reversed to profit or loss for the
     current period.

     Please refer to note III. 22 for the provision of impairment of intangible assets.

21. Research and development expenditures

     Expenditures on an internal research and development project are classified into expenditures on the research
     phase and expenditures on the development phase.

     Expenditures on the research phase shall be recognised in profit or loss for the current period when incurred.

     Expenditures on the development phase will be capitalised only when all of the following conditions are
     satisfied: it is technically feasible to complete the intangible asset so that it will be available for use or sale;
     the Company intends to complete the intangible asset and use or sell it; it can be demonstrated how the

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     Joincare Pharmaceutical Group                                                               Annual Report 2022


     intangible asset will generate economic benefits, including proving that the intangible assets or the products
     produced by it will have markets, or the intangible assets for internal use will be useful; there are adequate
     technical, financial and other resources to complete the development and the Company is able to use or sell
     the intangible assets; and expenditures on the development phase attributable to the intangible assets can be
     reliably measured. The development expenditures that do not satisfy the above conditions shall be recognised
     in profit or loss for the current period.

     Our research and development projects enter the development stage after meeting the above conditions and
     forming the project through the technical and economic feasibility studies.

     Capitalised expenditures on the development phase are shown as development expenditures on the balance
     sheet and reclassified as intangible assets on the date the project meets the intended purpose.

     Capitalisation conditions for specific research and development projects are as follows:

     ① For research and development projects that are not required to obtain clinical approvals, the period from
     the beginning of research and development to the pilot phase is treated as the research phase, and all
     expenditures shall be recognised in profit or loss for the current period when incurred; the period from the
     pilot phase to the obtaining of production approvals is treated as the development phase, and all expenditures
     shall be recognised as development expenditures and reclassified as intangible assets after the obtaining of
     production approvals.

     ② For research and development projects that require clinical approval, the period from the beginning of
     research and development to the obtaining of clinical approval is treated as the research phase, and all
     expenditures incurred shall be recognised in profit or loss for the current period when incurred; the period
     from the obtaining of clinical approval to the obtaining of production approval is treated as the development
     phase, and the expenditures shall be recognised as development expenditures and reclassified as intangible
     assets after the obtaining of production approval.

     ③ External technology transfer fees and the cost of purchasing clinical approvals can be recognised directly
     as development expenditures, and subsequent expenditures are accounted for in accordance with ① and ②
     above.

     ④ The Company reviews the latest research and development status of each project at the end of each year
     and if the research and development project no longer qualifies for the development stage, the corresponding
     development expenditure are recognised in profit or loss for the current period.

     ⑤ Where it is impossible to differentiate the expenditures on the research phase and the expenditures on
     the development phase, all the research and development expenditures are recognised in profit or loss for the
     current period.

     Please refer to note III.22 for the impairment testing methodology and impairment provision for intangible
     assets.

22. Impairment of assets

     The impairment of subsidiaries, associates and joint ventures in the long-term equity investments, investment
     properties subsequently measured at cost, fixed assets, construction in progress, right-of-use assets,
     intangible assets, etc. (Excluding inventories, deferred income tax assets and financial assets) are determined
     as follows:

     At the balance sheet date, the Company determines whether there may be evidence of impairment, if there is
     any, the Company will estimate the recoverable amount for impairment, and then test for impairment. For
     goodwill arising from a business combination, intangible assets with indefinite useful life and the intangible
     assets that have not yet ready for use are tested for impairment annually regardless of whether such evidence
     exists.

     The recoverable amount of an asset is determined by the higher amount of fair value deducting disposal costs

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     Joincare Pharmaceutical Group                                                                  Annual Report 2022


     and net present value of future cash flows expected from the assets. The Company estimates the recoverable
     amount based on individual asset; for individual asset which is difficult to estimate the recoverable amount,
     the recoverable amount of the asset group is determined based on the asset group involving the asset. The
     identification of the asset group is based on whether the cash flow generated from the asset group is
     independent of the major cash inflows from other assets or asset groups.

     When the asset or asset group’s recoverable amount is lower than its carrying amount, the Company reduces
     its carrying amount to its recoverable amount, the reduced amount is included in profit or loss, while the
     provision for impairment of assets is recognised.

     In terms of impairment test of the goodwill, the carrying amount of the goodwill, arising from business
     combination, shall be allocated to the related asset group in accordance with a reasonable basis at acquisition
     date. Those that are difficult to be allocated to related assets shall be allocated to related asset group. Related
     assets or assets group refer to those that can benefit from the synergies of business combination and are not
     larger than the Company’s recognised reporting segment.

     When there is an indication that the asset and asset group are prone to impair, the Company should test for
     impairment for asset and asset group excluding goodwill and calculate the recoverable amount and recognise
     the impairment loss accordingly. The Company should test for impairment for asset or the asset group
     including goodwill and compare the asset or asset group’s recoverable amount with its carrying amount,
     provision for impairment of assets shall be recognised when the recoverable amount of assets is lower than
     its carrying amount.

     Once impairment loss is recognised, it cannot be reversed in subsequent accounting periods.

23. Long-term deferred expenses

     The Company’s long-term deferred expenses measured at cost actually incurred and evenly amortised on
     straight-line basis over the expected beneficial period. For the long-term deferred expense items that cannot
     benefit in subsequent accounting period, their amortised value is recognised through profit or loss.

24. Employee compensation

(1) The scope of employee compensation

     Employee compensation are all forms of remuneration and compensation given by the Company in exchange
     for service rendered by employees or the termination of employment. Employee compensation include short-
     term employee compensation, post-employment benefits, termination benefits and other long-term employee
     benefits. Employee compensation include benefits provided to employees’ spouses, children, other
     dependants, survivors of the deceased employees or to other beneficiaries.

     According to liquidity, employment compensations are presented separately as “accrued payroll” item and
     “long-term employment compensation payable” item in the balance sheet.

(2) Short-term employee compensation

     During the accounting period in which the employees render the related services, wages, bonuses, social
     security contributions (including medical insurance, injury insurance, maternity insurance, etc.) and house
     funding are recognised as liability and included in the profit or loss for the current period or related asset
     costs.

(3) Post-employment benefits

     Post-employment benefit plans mainly includes defined contribution plans. Defined contribution plans are
     post-employment benefit plans under which an enterprise pays fixed contributions into a separate fund and
     will have no future obligations to pay the contributions. Defined contribution plans include the basic pension
     insurance, unemployment insurance, etc.

     The Company shall recognise, in the accounting period in which an employee provides service, the

                                                            195
      Joincare Pharmaceutical Group                                                                 Annual Report 2022


      contribution payable to a defined contribution plan as a liability, with a corresponding charge to the profit or
      loss for the current period or the cost of a relevant asset.

(4) Termination benefits

      The liability of employee compensation arising from termination benefits is recognised and included in profit
      or loss for the current period in the earlier date of the followings: The Company cannot unilaterally withdraw
      the offer of termination benefits because of an employment termination plan or a curtailment proposal; the
      Company recognises costs or expenses related to the restructuring that involves the payment of termination
      benefits.

      For the implementation of the internal retirement plan for employees, the economic compensation before the
      official retirement date is a termination benefit. The wage of and social insurance contributions for the
      internally retired employee which would have incurred from the date on which the employee cease rendering
      services to the Company to the scheduled retirement date will be included in the profit or loss for the current
      period. Economic compensation after the official retirement date (such as normal pension) should be treated
      as post-employment benefits.

(5) Other long-term employee benefits

      When other long-term employee benefits provided to the employees by the Company are satisfied the
      conditions of a defined contribution plan, those benefits shall be accounted for in accordance with the relevant
      provisions of the above defined contribution plans. When the benefits are satisfied the conditions of a defined
      benefit plan, those benefits shall be accounted for in accordance with the relevant provisions of the above
      defined benefit plans, except that the “change in remeasurement of the net liability or net assets of the defined
      benefit plans” in the cost of the related employee compensation shall be included in profit or loss for the
      current period or related asset costs.

25. Provision for liabilities

      An obligation related to a contingency is recognised as a provision when all of the following conditions are
      satisfied:

      (1) The obligation is a present obligation of the Company;

      (2) It is probable that an outflow of economic benefits will be required to settle the obligation;

      (3) The amount of the obligation can be measured reliably.

      Provisions are initially measured at the best estimate of the payment to settle the associated obligations and
      consider the relevant risk, uncertainty and time value of money. If the impact of time value of money is
      significant, the best estimate is determined as its present value of future cash outflow. The Company reviews
      the carrying amount of provisions at the balance sheet date and adjusts the carrying amount to reflect the best
      estimate.

      If the expenses for clearing of provisions is fully or partially compensated by a third party, and the
      compensated amount can be definitely received, it is recognised separately as asset. The compensated amount
      recognised shall not be greater than the carrying amount of the liability recognised.

26. Share-based payment and equity instruments

(1) Accounting treatment of share-based payment

      Share-based payments are transactions in which equity instruments are granted or liabilities are assumed on
      the basis of equity instruments in order to obtain services from employees or other parties. Share-based
      payment is classified into equity-settled share-based payment and cash-settled share-based payment.

     ① Equity-settled share-based payment


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     Joincare Pharmaceutical Group                                                                 Annual Report 2022


     Equity-settled share-based payment is measured at the fair value of the equity instruments granted to
     employees. If vesting is conditional upon completion of services in the pending period or fulfilment of
     performance conditions, at each balance sheet date during the pending period, based on the best estimates of
     the number of vested equity instruments, the services received for the period are recognised as the costs or
     expenses on a straight-line basis. Instruments which are vested immediately upon the grant are included in
     relevant costs or expenses at the fair value of equity instruments on the date of grant and capital reserves are
     increased accordingly.

     At each balance sheet date during the pending period, the Company makes the best estimate and revises the
     number of equity instruments expected to be exercisable based on subsequent information such as changes
     in the number of exercisable employees obtained from the latest available information. The effect of the
     above estimates is recognised as the relevant cost or expense in the current period, and capital surplus is
     adjusted accordingly.

     For the equity instruments granted under an equity-settled share-based payment for services from other
     parties, if the fair value of services received from other parties can be measured reliably, the fair value of the
     equity instruments is measured at the fair value of services from other parties on the grant date; if the fair
     value of services received from other parties cannot be measured reliably but the fair value of the equity
     instruments can be measured reliably, the fair value of the equity instruments on the date on which services
     are received shall be recognised as related costs or expenses, with a corresponding increase in owners' equity.

    ② Cash-settled share-based payment

     Cash-settled share-based payments are measured at the fair value of the liabilities (share-based or other equity
     instrument-based) assumed by the Company. Instruments which are vested immediately upon the grant are
     included in relevant costs or expenses at the fair value of liabilities assumed by the Company on the date of
     grant and liabilities are increased accordingly. If vesting is conditional upon completion of services in the
     pending period or fulfilment of performance conditions, at each balance sheet date during the pending period,
     based on the best estimates of the vesting situation, the services received for the period are recognised as the
     costs or expenses and corresponding liabilities at fair value of the liabilities assumed by the Company.

     At each balance sheet date and settlement date before the relevant liabilities are settled, the fair value of
     liabilities is re-measured and the resulting changes are included in the profit and loss for the current period.

(2) Accounting treatment for amendment and termination of share-based payments

     When the Company modifies the share-based payment plan, and if such modification increases the fair value
     of the equity instruments granted, the increase in services received will be recognised accordingly following
     the increase in fair value of the equity instruments; if such modification increases the number of equity
     instruments granted, the increase in fair value of the equity instruments is recognised as a corresponding
     increase in service achieved. The increase in fair value of the equity instruments refers to the difference in
     fair value on the date of modification before and after the modification in respect of the equity instruments.
     If the modification reduces the total fair value of the share-based payments or adopts any form that is
     unfavorable to employees to modify the terms and conditions of the share-based payment plan, accounting
     treatment will be continued to be conducted in respect of the services received and the modification will be
     deemed to have never occurred, unless the Company had cancelled part or all of the equity instruments
     granted.

     During the pending period, if the equity instruments granted are cancelled (except for failure to meet the non-
     market conditions of the vesting conditions), the Company will undertake an accelerated vesting in respect
     of the cancelled equity instruments that had been granted, include the remaining amount that shall be
     recognised during the pending period in the current profit and loss immediately and recognise capital reserve
     accordingly. Where employees or other parties are permitted to choose to fulfil non-vesting conditions but
     have not fulfilled during the pending period, the Company will treat the granted equity instruments as
     cancelled.

(3) Accounting treatment for share-based payments involving the Company and the shareholders or the de facto
controller of the Company

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      Joincare Pharmaceutical Group                                                                  Annual Report 2022


      For share-based payment transactions involving the Company and the shareholders or the de facto controller
      of the Company, the settlement enterprise and the enterprise receiving services (one under the Company
      while another external to the Company) shall follow the requirements below to conduct accounting treatment
      in the Company’s consolidated financial statements:

      ① For settlement enterprises settling through their own equity instruments, such share-based payment
      transaction will be treated as equity-settled share-based payment; except for this, such share-based payment
      transaction will be treated as cash-settled share-based payment.

      Where a settlement enterprise is an investor of an enterprise receiving services, the fair value of the equity
      instruments on the date of grant or the fair value of the liabilities that shall be assumed are recognised as
      long-term equity investment in the enterprise receiving services, at the same time, capital reserve (other
      capital reserve) or liabilities are recognised.

      ② Where an enterprise receiving services has no settlement obligations or grants its own equity instruments
      to employees, such share-based payment transaction will be treated as equity-settled share-based payment;
      where an enterprise receiving services has settlement obligations and grants equity instruments (other than
      its own) to employees, such share-based payment transaction will be treated as cash-settled share-based
      payment.

      For a share-based payment transaction occurring among enterprises under the Company where the enterprise
      receiving services and the settlement enterprise are not the same enterprise, such share-based payment
      transaction shall be recognised and measured in each of the respective financial statements of the enterprise
      receiving services and the settlement enterprise by reference to the above principles.

27. Preferred shares, perpetual bonds and other financial instruments

(1) Classification of financial liabilities and equity instruments

      The Company classifies the financial instrument or its components as financial assets, financial liabilities or
      equity instruments at the initial recognition based on the contract terms of the issued financial instrument and
      the economic substance it reflects, instead of only in legal form, and combine the definition of financial assets,
      financial liabilities and equity instruments.

(2) Accounting treatment of preferred shares, perpetual bonds and other financial instruments

      The financial instruments issued by the Company are initially recognised and measured in accordance with
      the financial instrument standards; thereafter, interest or dividends are accrued or distributed on each balance
      sheet date and processed in accordance with relevant specific accounting standards for enterprises. That is,
      on the basis of the classification of the financial instrument issued, the accounting treatment of interest
      expenses or dividend distributions of the instrument is determined. For financial instruments classified as
      equity instruments, interest expenses or dividend distributions are treated as profit distribution of the
      Company, and repurchases and cancellations are treated as changes in equity; for financial instruments
      classified as financial liabilities, interest expenses or dividend distributions are in principle treated according
      to borrowing costs, and gains or losses arising from repurchase or redemption are credited to profit or loss
      for the current period.

      The transaction costs such as charges and commissions incurred by the Company when issuing financial
      instruments, if classified as debt instruments and measured at amortised cost, are included in the initial
      measurement amount of the issued instrument; if classified as equity instruments, are deducted from equity.

28. Revenue

      The Company shall recognise revenue when the Company satisfies the performance obligation of the contract,
      that is, the customer obtains control of relevant goods or services.

      When the contract contains two or more performance obligations, on the effective date of the contract, the
      Company allocates the transaction price to each performance obligation based on the percentage of respective


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Joincare Pharmaceutical Group                                                                   Annual Report 2022


unit price of a good or service guaranteed by each performance obligation, and the revenue is measured
according to the transaction price allocated to each performance obligation.

If one of the following conditions is fulfilled, the Company satisfies a performance obligation over time;
otherwise, it satisfies a performance obligation at a point in time:

① When the customer simultaneously receives and consumes the benefits provided by the Company when
the Company performs its obligations under the contract.

② When the customer is able to control the commodity in progress in the course of performance by the
Company under the contract.

③ The product produced by the Company under the contract is irreplaceable and the Company has the right
to payment for performance completed to date during the term of the contract.

For a performance obligation satisfied over time, the Company shall recognise revenue over time by
measuring the process towards complete satisfaction of the performance obligation. When the progress of
performance cannot be reasonably determined, if the costs incurred by the Company are expected to be
recoverable, the revenue will be recognised to the extent of the costs incurred until the progress of
performance can be reasonably determined.

For a performance obligation satisfied at a point in time, the Company shall recognise revenue when the
customer obtains control of relevant goods or services. When determining whether the customer has obtained
control of the goods and services, the Company will consider the following indications:

① The Company has the current right to receive payment for the goods or services, which is when the
customers have the current payment obligations for the goods.

② The Company has transferred the legal title of the goods to the client, which is when the client possesses
the legal title of the goods.

③ The Company has transferred the physical possession of goods to the customer, which is when the
customer obtains physical possession of the goods.

④ The Company has transferred all of the substantial risks and rewards of ownership of the goods to the
customer, which is when the client obtains all of the substantial risks and rewards of ownership of the goods
to the customer.

⑤ When the customer has accepted the goods or services.

⑥ When other information indicates that the customer has obtained control of the goods.

A contract asset represents the Company’s right to consideration in exchange for goods or services that it has
transferred to a customer when that right is conditioned on factors other than passage of time, for which the
loss allowances for expected credit loss is recognised (see Note III.10(6)). The Company shall present any
unconditional (i.e. if only the passage of time is required) rights to consideration separately as a receivable.
A contract liability is the Company’s obligation to transfer goods or services to a customer for which the
Company has received consideration (or the amount is due) from the customer.

The contract assets and liabilities under the same contract shall be shown on a net basis. If the net amount
stated in debit balance, it will be presented under the items of “Contract assets” or “Other non-current assets”
according to its mobility; If the net amount stated in credit balance, it will be presented under the items of
“Contract liabilities” or “Other non-current liabilities” according to its mobility.

The Company enters into sales contracts with customers. Revenue from sales is recognised according to the
invoiced amount upon the delivery of goods to the designated carrier or purchaser according to the orders
received from customers; revenue from export sales is recognised mainly by adopting FOB mode according


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     Joincare Pharmaceutical Group                                                                 Annual Report 2022


     to custom declaration upon making declaration for goods and completing the export procedures.

29. Contract costs

     Contract costs are either the incremental costs of obtaining a contract with a customer or the costs to fulfil a
     contract with a customer.

     Incremental costs of obtaining a contract are those costs that the Company incurs to obtain a contract with a
     customer that it would not have incurred if the contract had not been obtained e.g. an incremental sales
     commission. The Company recognises as an asset the incremental costs of obtaining a contract with a
     customer if it expects to recover those costs. Other costs of obtaining a contract are expensed when incurred.

     If the costs to fulfil a contract with a customer are not within the scope of inventories or other accounting
     standards, the Company recognises an asset from the costs incurred to fulfil a contract only if those costs
     meet all of the following criteria:

     ① The costs relate directly to an existing contract or to a specifically identifiable anticipated contract,
     including direct labour, direct materials, allocations of overheads (or similar costs), costs that are explicitly
     chargeable to the customer and other costs that are incurred only because the Company entered into the
     contract;

     ② The costs generate or enhance resources of the Company that will be used in satisfying (or in continuing
     to satisfy) performance obligations in the future;

     ③ The costs are expected to be recovered.

     Assets recognised for the incremental costs of obtaining a contract and assets recognised for the costs to fulfil
     a contract (the “assets related to contract costs”) are amortised on a systematic basis that is consistent with
     the transfer to the customer of the goods or services to which the assets relate and recognised in profit or loss
     for the current period.

     The Company recognises an impairment loss in profit or loss to the extent that the carrying amount of an
     asset related to contract costs exceeds:

     ① Remaining amount of consideration that the Company expects to receive in exchange for the goods or
     services to which the asset relates;

     ② The cost estimated to be happened for the transfer of related goods or services.

     The costs of contract performance recognised as assets, if the amortisation period is less than one year or a
     normal operating cycle upon the initial recognition, are presented as “Inventories” item, and if the
     amortisation period is more than one year or a normal operating cycle upon the initial recognition, are
     presented as “Other non-current assets” item.

     The contract obtaining costs recognised as assets, if the amortisation period is less than one year or a normal
     operating cycle upon the initial recognition, are presented as “Other current assets” item, and if the
     amortisation period is more than one year or a normal operating cycle upon the initial recognition, are
     presented as “Other non-current assets” item.

30. Government grants

     A government grant shall be recognised only when the enterprise can comply with the conditions attaching
     to the grant and the enterprise can receive the grant.

     If a government grant is in the form of a transfer of a monetary asset, the item is measured at the amount
     received. If a government grant is in the form of a transfer of a non-monetary asset, the item is measured at
     fair value, when fair value is not reliably determinable, the item is measured at a nominal amount of RMB1.



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      Joincare Pharmaceutical Group                                                                 Annual Report 2022


      Government grant related to assets represents the government grant received for acquisition and construction
      of long term assets, or forming long term assets in other ways. Except for these, all are government grant
      related to income.

      Regarding to the government grant not clearly defined in the official documents and can form long term
      assets, the part of government grant which can be referred to the value of the assets is classified as government
      grant related to assets and the remaining part is government grant related to income. For the government
      grant that is difficult to distinguish, the entire government grant is classified as government grant related to
      income.

      The government grant related to assets is recognised as deferred income and would be transferred to profit
      or loss in reasonable and systematic manner within the period of use of the relevant assets. The government
      grant related to income which is used to compensate the relevant costs or losses incurred should be recognised
      in the profit or loss for the current period; the government grant related to income which is used to compensate
      the relevant costs or losses for the subsequent period is recognised as deferred income and shall be recognised
      in profit or loss during the relevant cost or loss confirmation period. Government grants measured in nominal
      terms are directly included in the profit or loss for the current period. The Company has adopted a consistent
      approach to the same or similar government grant business.

      The government grants related to daily activities are recognised as other gains in accordance with the
      substance of economic business. Government grants that are not related to daily activities are recognised as
      non-operating income.

      If the recognised government grants need to be refunded, adjust the carrying amount of assets when the
      carrying amount of assets is offset at the time of initial recognition; the balance of deferred income is offset
      against the carrying amount of the balance of deferred income and the excess is recognised in the profit or
      loss for the current period. Other circumstances, it is directly recognised in the profit or loss for the current
      period.

31. Deferred tax assets and deferred tax liabilities

(1) Current tax

      At the balance sheet date, for the current tax liabilities (or assets) arising from the current period and the
      previous period, should be measured by the tax of the estimated payable (returnable) amount which be
      calculated according to the regulations of the tax law. The amount of the tax payable which is based by the
      calculation of the current tax expenses, are according to the result measured from the corresponding
      adjustment of the pre-tax accounting profit of the current period which in accord to the relevant regulations
      of the tax law.

(2) Deferred tax assets and deferred tax liabilities

      The difference between the carrying amount of an asset or liability and its tax basis, as well as the temporary
      differences arising from differences between the carrying amount and tax basis of items that are not
      recognised as assets and liabilities but in accordance with the tax law, can be recognised as deferred tax assets
      and deferred tax liabilities by adopting the balance sheet liability method.

      No deferred tax liability is recognised for a temporary difference arising from the initial recognition of
      goodwill the initial recognition of assets or liabilities due to a transaction other than a business combination,
      which affects neither accounting profit nor taxable profit (or deductible loss). Besides, no deferred tax assets
      well be recognised for the taxable temporary differences related to the investments in subsidiaries, associates
      and joint ventures, if the Company can control the time of the reverse of temporary differences as well as the
      temporary differences are unlikely to be reversed in the foreseeable future. Except for the above exceptions,
      the Company recognises all deferred income tax liabilities arising from other taxable temporary differences.

      The deductible temporary differences the initial recognition of assets or liabilities arising from transactions
      that are neither a business combination, nor do they affect accounting profits and taxable income (or
      deductible losses), will not be recognised as related deferred income tax assets. In addition, as for the taxable


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      Joincare Pharmaceutical Group                                                                     Annual Report 2022


      temporary differences associated with investments in subsidiaries, associates and joint ventures, if the
      Company is able to control the timing of the reversal of the temporary differences, and the temporary
      differences may not be reversed in the foreseeable future, the related deferred income tax assets will also not
      be recognised. Except for the above exceptions, the Company recognises a deferred tax asset arising from
      other deductible temporary differences, to the extent that it is probable that taxable income will be available
      against which the deductible temporary differences.

      The Company recognises a deferred tax asset for the carry-forward of deductible losses and tax credits to
      subsequent periods, to the extent that it is probable that future taxable profits will be available against which
      deductible losses and tax credits can be utilised.

      At the balance sheet date, deferred tax assets and deferred tax liabilities are measured at the tax rates that are
      expected to apply to the period when the asset is realised or the liability is settled in accordance with the
      provisions of the tax law.

      At the balance sheet date, the Company reviews the carrying amount of a deferred tax asset. If it is probable
      that sufficient taxable profits will not be available in future periods to allow the benefit of the deferred tax
      asset to be utilised, the carrying amount of the deferred tax asset is reduced. Any such reduction in amount
      is reversed when it becomes probable that sufficient taxable profits will be available.

(3) Tax expenses

      The tax expenses comprise current tax and deferred tax.

      The rest current tax and deferred tax expenses or revenue should be included into current gains and losses
      expect for the current tax and the deferred tax related to the transaction and events that be confirmed as other
      comprehensive income or be directly included in the shareholders’ equity which should be included in other
      comprehensive income or shareholders’ equity as well as the book value for adjusting the goodwill of the
      deferred income tax occurs from the business combination.

(4) Offset of tax

      The current tax assets and liabilities of the Company should be listed by the written-off net amount which
      intend to execute the net amount settlement as well as the assets acquiring and liabilities liquidation at the
      same time while owns the legal rights of settling the net amount.

      The deferred tax assets and liabilities of the Company should be listed as written-off net amount when having
      the legal rights of settling the current tax assets and liabilities by net amount and the deferred tax and liabilities
      is relevant to the tax which be collected from the same taxpaying bodies by the same tax collection and
      administration department or is relevant to the different taxpaying bodies but during each period which there
      is significant reverse of the deferred income assets and liabilities in the future and among which the involved
      taxpaying bodies intend to settle the current income tax and liabilities by net amount or are at the same time
      acquire the asset as well as liquidate the liabilities.

32. Leases

(1) Identification of leases

      At the inception of a contract, the Company, as a lessee or lessor, assesses if the customer in a contract has
      the right to obtain substantially all the economic benefits from use of the identified assets and the right to
      direct the use of the identified assets in the period of use. The Company would identify that a contract is a
      lease, or contains a lease if a party of the contract transfers the right to control the use of one or more identified
      assets for a period of time in exchange for consideration.

(2) The Company as the lessee

      At the inception of a lease, the Company recognises all its leases as the right-of-use assets and lease liabilities,
      except for the short-term leases and the leases of low-value assets which are treated with a simplified
      approach.

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     Joincare Pharmaceutical Group                                                                   Annual Report 2022


     For the accounting policies on the right-of-use assets, please refer to Note III. 33.

     Lease liabilities are initially measured based on the present value of outstanding lease payment at the
     inception of a lease, discounted using the interest rate implicit in the lease or the incremental borrowing rate.
     Lease payment include: fixed payments and in-substance fixed payments, less any lease incentives (if there
     is a lease incentive); variable lease payment that are based on an index or a rate; the exercise price of a
     purchase option if the lessee is reasonably certain to exercise that option; payments of penalties for
     terminating the lease option, if the lease term reflects that the lessee will exercise that option; and amounts
     expected to be payable under the guaranteed residual value provided by the lessee. The Company shall
     subsequently calculate the interest expenses of lease liabilities over the lease term at the fixed periodic interest
     rate, and include it into the profit or loss for the current period. Variable lease payments not included in the
     measurement of lease liabilities are charged to profit or loss in the period in which they actually arise.

     Short-term lease

     Short-term lease refers to the lease that the lease term does not exceed 12 months from the inception of a
     lease, and the lease that includes the option of purchase is not a short-term lease.

     The Company recognises the amount of lease payments of short-term lease in the cost of the related asset or
     the profit or loss for the current period, on a straight-line method over each period of the lease term.

     Leases of low-value assets

     For the Leases of low-value assets, the Company chooses to adopt the above simplified treatment method in
     accordance with the specific conditions of each lease.

     The Company recognised the lease payments for the leases of low-value assets in the relevant asset cost or
     the profit or loss for the current period on a straight-line basis over each period of the lease term.

(3) The Company as the lessor

     When the Company is the lessor, the lease that substantially transfers all the risks and rewards related to the
     ownership of assets is recognised as a finance lease, and leases other than finance leases are recognised as
     operating leases.

     Finance leases

     In a financial lease, the Company uses the net investment in leases as the carrying amount of finance lease
     receivables at the inception of a lease. The net investment in leases is the sum of the unguaranteed residual
     value and the present value of the outstanding lease payment at the inception of a lease, discounted using the
     interest rate implicit in the lease. The Company, as the lessor, calculates and recognises the interest income
     over each period of the lease term at a fixed periodic interest rate. Variable lease payments not included in
     the measurement of the lease liability, which are obtained by the Company as a lessor, are recognised in profit
     or loss as incurred.

     The termination of recognition and impairment of financial lease receivables is accounted for in accordance
     with the provisions of “Accounting Standards for Business Enterprises No. 22 – Recognition and
     Measurement of Financial Instrument” and “Accounting Standards for Business Enterprises No. 23 –
     Transfer of Financial Assets”.

     Operating leases

     For the rental of operating leases, the Company recognises it in the profit or loss for the current period on a
     straight- line basis over each period of the lease term. The initial direct cost incurred in connection with an
     operating lease shall be capitalised and amortised on the same basis for recognition of rental income during
     the lease term, and shall be included in instalments in the profit or loss for the current period. The variable
     lease payment, which is obtained in connection with an operating lease and not included in the lease
     receivables, shall be included in the profit and loss for the current period when they actually occur.


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     Joincare Pharmaceutical Group                                                                Annual Report 2022


33. Right-of-use assets

(1) Recognition condition of right-of-use assets

     The right-of-use assets of the Company are defined as the right of underlying assets in the lease term for the
     Company as a lessee.

     Right-of-use assets are initially measured at cost as at the commencement date of the lease, which consists
     of: the amount of the initial measurement of the lease liability; any lease payments made at or before the
     commencement date of the lease less any lease incentives received if any; initial direct expenses incurred by
     the Company as a lessee; costs to be incurred by the Company as a lessee in dismantling and removing a
     leased asset, restoring the site on which it is located or restoring the leased assets to the condition required
     by the terms and conditions of the lease. The Company as a lessee recognises and measures the costs of
     demolition and restoration according to “Accounting Standards for Business Enterprises No.13 –
     Contingencies”, and subsequently adjusts for any remeasurement of lease liability.

(2) Depreciation method of right-of-use assets

     The Company calculates depreciation on a straight-line basis. Right-of-use assets in which the Company as
     a lessee is reasonably certain to obtain ownership of the underlying leased assets at the end of the lease term
     are depreciated over the remaining useful life. Otherwise, right-of-use assets are depreciated over the shorter
     of the lease term and its remaining useful life.

(3) For methods of impairment testing and provision for impairment for right-of-use assets, please refer to note III.
     22.

34. Repurchase of shares

     Prior to cancellation or transfer of shares repurchased, the Company recognises all expenditures arising from
     share repurchase as cost of treasury shares in the treasury share account. Considerations and transaction fee
     incurred from the repurchase of shares shall lead to the elimination of owners’ equity and does not recognise
     profit or loss when shares of the Company are repurchased, transferred or cancelled.

     The difference between the actual amount received and the carrying amount of the treasury stock are
     recognised as capital reserve when the treasury stocks are transferred, if the capital reserve is not sufficient
     to be offset, the excess amount shall be recognised to offset surplus reserve and undistributed profit. When
     the treasury stocks are cancelled, the capital shall be eliminated according to the number of shares and par
     value of cancellation shares, the difference between the actual amount received and the carrying amount of
     the treasury stock are recognised as capital reserve, if the capital reserve is not sufficient to be offset, the
     excess amount shall be recognised to offset surplus reserve and undistributed profit.

35. Restricted shares

     If the Company grants the restricted shares to incentive participants under the Share Options Incentive
     Scheme, the incentive participants subscribe for the shares first. If the unlocking conditions stipulated in the
     Share Options Incentive Scheme cannot be fulfilled subsequently, the Company repurchases the shares at the
     predetermined price. If the registration and other capital increase procedures for the restricted shares issued
     to employees are completed in accordance with relevant regulations, the Company recognises share capital
     and capital reserve (or capital premium) based on the subscription money received from the employees on
     the grant date; and recognises treasury shares and other payables for repurchase obligation.

36. Significant accounting judgements and estimates

     Significant accounting estimates and critical assumptions adopted by the Company are continually evaluated
     based on historical experience and other factors, including expectations of future events that are believed to
     be reasonable. The significant accounting estimates and critical assumptions that have a significant risk of
     causing a material adjustment to the carrying amounts of assets and liabilities within the next accounting year
     are set out below:


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Joincare Pharmaceutical Group                                                                 Annual Report 2022


(1) Classification of financial assets

Significant judgements involved in determining the classification of financial assets include analysis of
business mode and characteristics of the contractual cash flows.

Factors considered by the Company in determining the business model of financial assets management for a
group of financial assets include past experience on how financial asset’s performance is evaluated and
reported to key management personnel, how risks affecting the performance of financial asset are assessed
and managed and how managers of related businesses are compensated.

When assessing whether the contractual cash flows of financial assets are consistent with basic lending
arrangement, the Company adopts the following significant judgements: whether the time distribution or
amounts of the principal within the duration may change due to early repayment and other reasons; whether
the interest includes only the time value of money, credit risk, other basic lending risks and the consideration
for cost and profit. For example, the amounts of early repayment only reflect principal unpaid, the interest
based on principal unpaid and reasonable compensation paid for early termination of a contract.

(2) Measurement of ECL for accounts receivables

The Company calculates ECL of accounts receivables according to their exposure at default and ECL rate,
and determines ECL rate based on probability of default and loss given default. When determining ECL rate,
the Company adopts data like historical credit loss experience in combination with current situation and
forward-looking information to adjust historical data. When considering forward-looking information, the
Company uses indicators including the risk of economic downturn, external market environment, technology
environment and changes on customer situation. The Company periodically monitors and reviews
assumptions relevant to the measurement of ECL.

(3) Impairment of non-current assets other than financial assets (other than goodwill)

The Company determines at the balance sheet date whether there are signs of possible impairment of non-
current assets other than financial assets. For intangible assets that have not yet reached usable condition, in
addition to the annual impairment test, when there are signs of impairment, the impairment test is also carried
out. Other non-current assets, other than financial assets, are tested for impairment when there are indications
that their carrying amount is not recoverable. An impairment occurs when the carrying amount of an asset or
group of assets is higher than the recoverable amount, which is the present value of the fair value net of
disposal costs and projected future cash flows. The net amount of fair value less disposal costs, is determined
by referencing to the agreed sale price or observable market value of a similar asset in an arm's length
transaction, less incremental costs directly attributable to the disposal of that asset. When projecting the
present value of future cash flows, management must estimate the projected future cash flows of the asset or
group of assets and select an appropriate discount rate to determine the present value of future cash flows.

(4) Impairment of goodwill

The Company evaluates whether goodwill is impaired at least once a year. This requires an estimate of the
value in use of the asset groups to which the goodwill is allocated. In estimating the value in use, the Company
needs to estimate the future cash flows generated from the asset groups and also to choose an appropriate
discount rate in order to calculate the present value of the future cash flows.

(5) Development costs

Determining the amounts to be capitalised requires the management to make assumptions regarding the
expected future cash flows generated from the relevant assets, discount rates to be applied and the expected
period of benefits.

(6) Deferred tax assets

The deferred income tax assets will be recognised for all unused tax losses to the extent that it is probable
that there will be sufficient taxable profits against which the loss is utilised. This requires the management to


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     Joincare Pharmaceutical Group                                                                 Annual Report 2022


     exert numerous judgments to estimate the timing and amount of the future taxable profits so as to determine
     the amount of deferred income tax assets to be recognised with reference to the tax planning strategy.

     (7) Revenue recognition

     As stated in note III. 28, the Company makes the following significant accounting judgements and estimates
     in terms of revenue recognition: identifying customer contracts; estimating the recoverability of the
     considerations that are entitled to be obtained by transferring goods to customers; identifying the performance
     obligation in the contract; estimating the variable consideration in the contract and cumulative revenue
     recognised where it is highly probable that a significant reversal therein will not occur when the relevant
     uncertainty is resolved; assessing whether there is a significant financing component in the contract;
     estimating the individual selling price of the individual performance obligation in the contract, etc. The
     Company makes judgments primarily based on historical experiences and works. Changes in these significant
     judgments and estimates may have significant impacts on the operating income, operating costs, and profit
     or loss of the current or subsequent periods.

     (8) Determination of the fair value of unlisted equity investment

     The fair value of unlisted equity investments represents the expected future cash flows discounted at the
     prevailing discount rate of items with similar terms and risk characteristics. It requires the Company to
     estimate the expected future cash flows and discount rates, and therefore there is uncertainty. Under limited
     circumstances, if the information used to determine the fair value is insufficient, or the possible estimated
     amount of fair value is widely distributed, and cost represents the best estimate of the fair value within such
     scope, the cost may represent an appropriate estimate of the fair value within such distribution scope.

37. Changes in significant accounting policies and accounting estimates and correction to accounting errors

(1) Changes in significant accounting policies

① Interpretation No. 15 of Accounting Standards for Business Enterprises

     The Ministry of Finance issued the Interpretation No. 15 of Accounting Standards for Business Enterprises
     (Cai Kuai [2021] No. 35, hereinafter referred to as “Interpretation No. 15”) in December 2021.

     Interpretation No. 15 stipulates that when the Company sells the products or by-products produced before
     the fixed assets reach the status of intended use or during the research and development process (hereinafter
     collectively referred to as “revenue in trial operation”), in accordance with the “Accounting Standards for
     Business Enterprises No. 14 - Revenue", "Accounting Standards for Business Enterprises No. 1 - Inventories"
     and other regulations, the revenue and costs relevant to the trial operation shall be accounted for separately
     and included in the profit or loss for the current period, rather than the net amount of sale revenue after
     offsetting relevant costs of the trial operation sales write-off against the cost of fixed assets or research and
     development expenditures. When the relevant products or by-products produced by the trial operation are
     sold externally, those that meet the requirements of the "Accounting Standards for Business Enterprises No.
     1 - Inventory" should be recognized as inventories, and those that meet the relevant asset recognition
     conditions in other relevant Accounting Standards for Business Enterprises should be recognized as related
     assets.

     The Company implemented Interpretation No. 15 “Accounting treatment for the sale of products or by-
     products produced by the enterprise before the fixed assets reach the intended usable state or during the
     research and development process” from 1 January 2022.

     Interpretation No. 15 stipulates that in onerous contracts, "costs that will inevitably occur in performing
     contractual obligations" should reflect the minimum net cost of exiting the contract, i.e. the lower of the cost
     of performing the contract and the compensation or penalty for failure to perform the contract. The cost for
     the Company to perform the contract includes the incremental cost of performing the contract and the
     apportioned amount of other costs directly related to the performance of the contract, of which the
     incremental cost of fulfilling the contract includes direct labor, direct materials, etc.; the apportioned amount
     of other costs directly related to the performance of the contract includes the apportioned amount of the

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     Joincare Pharmaceutical Group                                                                  Annual Report 2022


     depreciation expense of the fixed assets used to perform the contract.

     The Company implemented Interpretation No. 15 “Judgment on Onerous Contracts” from 1 January 2022.

     The adoption of Interpretation No. 15 did not have any significant impact on the financial position and
     operating results of the Company.

② Interpretation No. 16 of Accounting Standards for Business Enterprises

     The Ministry of Finance issued the Interpretation No. 16 of Accounting Standards for Business Enterprises
     (Cai Kuai [2022] No. 31, hereinafter referred to as “Interpretation No. 16”) in November 2022.

     Interpretation No. 16 stipulates that for financial instruments such as perpetual bonds classified as equity
     instruments, the Company shall recognize the income tax impact related to dividends when confirming
     dividends payable. For the distributed profit comes from the transaction or event that generated profit or loss
     in the past, the income tax effect of the dividend should be included in the profit or loss for the current period;
     For the profit distributed from the transactions or event previously recognized in the owner’s equity, the
     income tax effect of the dividend should be included in the owner’s equity item.

     Interpretation No. 16 stipulates that if the Company modifies the terms and conditions of a cash-settled share-
     based payment agreement to make it an equity-settled share-based payment, on the date of modification, the
     Company shall measure the equity-settled share-based payment according to the fair value of the equity
     instrument granted on the day, include the services obtained in the capital reserve, and at the same time
     derecognize the liabilities of the cash-settled share-based payment recognized on the date of modification,
     the difference between the two is included in the profit or loss for the current period. If the vesting period is
     extended or shortened due to the revision, the Company shall perform the above accounting treatment
     according to the revised vesting period (without considering the relevant accounting treatment provisions of
     adverse revisions).

     The adoption of Interpretation No. 16 did not have any significant impact on the financial position and
     operating results of the Company.

(2) Changes in significant accounting estimates

     None.

IV. Taxation

1. Major taxes and their tax rates

       Tax category                                         Tax basis                            Statutory tax rate %
       Value-added tax                             Taxable revenue                                         3, 6, 13
       Urban maintenance and construction tax      Turnover tax paid                                         1, 5, 7
       Education surcharge                         Turnover tax paid                                              3
       Local education surcharge                   Turnover tax paid                                        Note 1
       Enterprise income tax                       Taxable profit                                           Note 2

     Note 1. The Company and its subsidiaries that are incorporated in Shenzhen and Zhuhai shall pay local
     education surcharges that are charged as 2% of the turnover tax payable. Other subsidiaries shall pay local
     education surcharges according to the tax rate as specified at their places of incorporation on the basis of
     turnover tax payable.



     Note 2. Enterprise income tax rate implementation is as follows:



                                                             207
     Joincare Pharmaceutical Group                                                                        Annual Report 2022


                                              Entity                                                     Income tax rate %
      Hong Kong Health Pharmaceutical Industry Company Limited (香港健康药业有限公
      司), Livzon Pharmaceutical Biotechnology Co., Ltd. (丽珠医药生物科技有限公司),
                                                                                                                       16.5
      Lian (Hong Kong) Co., Ltd. (丽安香港有限公司), Livzon Biologics Hong Kong
      Limited (丽珠生物科技香港有限公司)
                                                                                                  0 or 12 (Tax rate is 12%
                                                                                              where the taxable income is
                                                                                                MOP600,000 or more; for
      Companhia de Macau Carason Limitada (澳门嘉安信有限公司), Li Zhu (Macau)
                                                                                                those with taxable income
      Limitada (丽珠(澳门) 有限公司)                                                         less than MOP600,000, they
                                                                                               are exempted from income
                                                                                                                     taxes.)
      The Company and Shenzhen Taitai Pharmaceutical Industry Co., Ltd. (深圳太太药业
      有限公司), Shenzhen Haibin Pharmaceutical Co., Ltd. (深圳市海滨制药有限公司),
      Xinxiang Haibin Pharmaceutical Co., Ltd. (新乡海滨药业有限公司), Jiaozuo
      Joincare Bio Technological Co., Ltd. (焦作健康元生物制品有限公司), Shanghai
      Frontier Health Pharmaceutical Technology Co., Ltd. (上海方予健康医药科技有限
      公司), Guangzhou Joincare Respiratory Medicine Engineering Technology Co., Ltd.
      (广州健康元呼吸药物工程技术有限公司), Joincare Haibin Pharmaceutical Co., Ltd.
      (健康元海滨药业有限公司);Livzon Group and subsidiaries of Livzon Group, Livzon
      Group Limin Pharmaceutical Manufacturing Factory (丽珠集团利民制药厂) . Livzon
      Group Livzon Pharmaceutical Manufacturing Factory (丽珠集团丽珠制药厂) .
      Zhuhai FTZ Livzon Hecheng Pharmaceutical Manufacturing Co., Ltd. (珠海保税区丽
                                                                                                                         15
      珠合成制药有限公司), Shanghai Livzon Pharmaceutical Manufacturing Co., Ltd. (上
      海丽珠制药有限公司), Livzon Group Xinbeijiang Pharmaceutical Manufacturing
      Inc. (丽珠集团新北江制药股份有限公司). Sichuan Guangda Pharmaceutical
      Manufacturing Co., Ltd. (四川光大制药有限公司), Zhuhai Livzon Diagnostics Inc.
      (珠海丽珠试剂股份有限公司), Livzon Group Fuzhou Fuxing Pharmaceutical Co.,
      Ltd. (丽珠集团福州福兴医药有限公司), Shanghai Livzon Biotechnology Co., Ltd.
      (上海丽珠生物科技有限公司), Livzon Group (Ningxia) Pharmaceutical
      Manufacturing Co., Ltd. (丽珠集团(宁夏) 制药有限公司), Livzon MABPharm Inc.
      (珠海市丽珠单抗生物技术有限公司), Zhuhai Lihe Medical Diagnostic Products
      Co., Ltd. (珠海丽禾医疗诊断产品有限公司), Zhuhai Livzon Chinese Medicine
      Modern Technology Co., Ltd. (珠海市丽珠中药现代化科技有限公司)
      Livzon MAB Pharm (US) Inc. (丽珠单抗生物技术(美国) 有限公司)                                                       21
                                                                                            17 or 24 (registered capital of
                                                                                              less than MYR 2.5 million,
                                                                                                 the tax rate is 17% on the
                                                                                                first profit less than MYR
      LIVZON BIOLOGICS (MALAYSIA) SDN. BHD.                                                         600,000; the registered
                                                                                                 capital exceeds MYR 2.5
                                                                                             million or the profit exceeds
                                                                                            MYR 600,000, the tax rate is
                                                                                                                       24%)
      Health Investment Holdings Ltd, Joincare Pharmaceutical Group
       Industry Co.,Ltd., Livzon International Ventures, Livzon International Ventures I,                        0 (Note1)
      Livzon International Ventures II
      Other subsidiaries                                                                                                 25

     Note 1. Companies registered in the British Virgin Islands and the Cayman Islands are not subject to
     enterprise income tax.

2. Tax incentives and approval documents

     (1) Preferential value added tax
     In accordance with the Announcement on Value Added Tax on Biological Products Sold by Pharmaceutical
     Operation Enterprises issued by the State Administration of Taxation (Announcement of State Administration
     of Taxation 2012 No. 20) and the Notice of the Ministry of Finance, the General Administration of Customs,

                                                                 208
     Joincare Pharmaceutical Group                                                             Annual Report 2022


     the State Administration of Taxation and the State Drug Administration on the Value-Added Tax Policies for
     Anti-Cancer Drugs (Caishui [2018] No. 47), the biological products sold by the Company are subject to value
     added tax at 3% by the simple approach.

     (2) Preferential enterprise income tax
     The Company enjoys the preferential income tax policy for high-tech enterprises for the 3 years from 2022;
     The Company's subsidiaries, Shenzhen Taitai Pharmaceutical Co., Ltd. (深圳太太药业有限公司), Shenzhen
     Haibin Pharmaceutical Co., Ltd (深圳市海滨制药有限公司), Xinxiang Haibin Pharmaceutical Co., Ltd. (新
     乡海滨药业有限公司) and Shanghai Frontier Health Medicine Technology Co., Ltd. (上海方予健康医药
     科技有限公司) are entitled to enjoy preferential income tax policies applicable to high and new technology
     enterprises for 3 years with effective from 2020. Joincare Haibin Pharmaceutical Co., Ltd. (健康元海滨药
     业有限公司) entitled to enjoy preferential income tax policies applicable to high and new technology
     enterprises for 3 years with effective from 2020. Jiaozuo Joincare Bio Technological Co., Ltd. (焦作健康元
     生物制品有限公司), Guangzhou Joincare Respiratory Drug Engineering Technology Co., Ltd. (广州健康
     元呼吸药物工程技术有限公司) have re-applied for high-tech enterprise certification in this period. Livzon
     Group and its subsidiaries— Livzon Group Limin Pharmaceutical Manufacturing Factory (丽珠集团利民
     制药厂), Livzon Group Livzon Pharmaceutical Factory (丽珠集团丽珠制药厂), Zhuhai FTZ Livzon
     Hecheng Pharmaceutical Manufacturing Co., Ltd. (珠海保税区丽珠合成制药有限公司), Shanghai Livzon
     Pharmaceutical Manufacturing Co., Ltd. ( 上 海 丽 珠 制 药 有 限 公 司 ), Livzon Group Fuzhou Fuxing
     Pharmaceutical Co., Ltd. (丽珠集团福州福兴医药有限公司 ) and Sichuan Guangda Pharmaceutical
     Manufacturing Co., Ltd. (四川光大制药有限公司) are entitled to enjoy preferential income tax policies
     applicable to high and new technology enterprises for 3 years with effective from 2020. Livzon Group
     Xinbeijiang Pharmaceutical Manufacturing Inc. (丽珠集团新北江制药股份有限公司), Zhuhai Livzon
     Diagnostics Inc. (珠海丽珠试剂股份有限公司) and Livzon MABPharm Inc. (珠海市丽珠单抗生物技术
     有限公司) have re-applied for high-tech enterprise certification in this period, and has been announced to be
     identified as a high-tech enterprise. Shanghai Livzon Biotechnology Co., Ltd. (上海丽珠生物科技有限公
     司) are entitled to preferential income tax policies applicable to high and new technology enterprises for 3
     years with effective from 2021. Livzon Group (Ningxia) Pharmaceutical Manufacturing Co., Ltd. (丽珠集
     团(宁夏) 制药有限公司) was approved to enjoy the enterprise taxation preference of the Encouraged
     Industries in Western China. The above companies were subject to enterprise income tax rate of 15% for the
     period.

     In accordance with Article 27 of the Enterprise Income Tax Law of the People's Republic of China and Article
     86 of the Regulations for the Implementation of the Enterprise Income Tax Law of the People's Republic of
     China, the business of planting Chinese herbal medicines engaged by the subsidiaries of the Livzon, Datong
     Livzon Qiyuan Medicine Co., Ltd. (大同丽珠芪源药材有限公司) and Longxi Livzon Shenyuan Medicine
     Co., Ltd. (陇西丽珠参源药材有限公司) are exempted from enterprise income tax.

     According to the "Notice of the Ministry of Finance and the State Administration of Taxation on the
     Preferential Policies for Enterprise Income Tax in the Hengqin Guangdong-Macao Deep Cooperation Zone"
     (Cai Shui [2022] No. 19), enterprise income tax is levied at a reduced rate of 15% for qualified industrial
     enterprises located in the Hengqin Guangdong-Macao Deep Cooperation Zone. The Livzon Grou’s
     subsidiaries, Zhuhai Lihe Medical Diagnostic Products Co., Ltd. (珠海丽禾医疗诊断产品有限公司) and
     Zhuhai Livzon Chinese Medicine Modern Technology Co., Ltd. (珠海市丽珠中药现代化科技有限公司)
     meet the relevant conditions and are subjected to 15% enterprise income tax rate for the current period.

     According to the preferential tax policies for small low-profit enterprises, the portion of annual taxable
     income of a small low profit enterprise which does not exceed RMB1 million is subject to enterprise income
     tax at a tax rate of 2.5%; the portion over RMB1 million but not exceeding RMB3 million is subject to
     enterprise income tax at a tax rate of 5%.

V. Notes to the items of consolidated financial statements
1. Cash and bank balances


                                                         209
     Joincare Pharmaceutical Group                                                                Annual Report 2022


                              Item                            2022.12.31                      2021.12.31
       Cash on hand                                                      231,883.95                    225,179.98
       Cash at bank                                               14,792,867,005.08             11,554,754,721.43
       Other monetary funds                                           15,389,221.93                174,250,489.57
                              Total                               14,808,488,110.96             11,729,230,390.98
         Including: Total amount of money deposited
                                                                   1,491,900,539.35              1,309,853,620.27
       abroad

     ① Other monetary funds are mainly deposits for investments, deposits under guarantee of letter of guarantee,
     issuing letters of credit and foreign exchange forward contracts, etc.

     ② Restricted funds relating to issuing letters of credit, bank acceptance bills and foreign exchange forward
     contracts, etc. in other monetary funds were deducted from cash and cash equivalents in the cash flow
     statement. Apart from these restricted funds, there is no other charge, pledge or lock up on the cash at bank
     balance that may limit its use, is kept outside China and may have probable risks in its collection. Below are
     the details of the use of restricted monetary funds:

                                 Item                              2022.12.31                   2021.12.31

       Deposits for letter of credit                                          444,032.37                   1,788,607.74

       Deposits for bank acceptance bills                                     947,255.39                   6,004,457.37

       Deposits for other business                                              1,120.00                   3,949,531.92

                                Total                                    1,392,407.76                  11,742,597.03

2. Financial assets held for trading

(1) Classification

                               Item                              2022.12.31                    2021.12.31

       Financial assets held for trading                             109,015,664.98                   184,638,344.31
       Including: Debt instruments investment                            934,289.94                         940,162.94
              Equity instruments investment                          102,648,863.47                   176,321,853.05
              Derivative financial assets                               5,432,511.57                       7,376,328.32
                               Total                                 109,015,664.98                   184,638,344.31
     ① The Company's investments in equity instruments and debt instruments for financial assets held for
     trading at period end were listed for trading on Shenzhen Stock Exchange, Hong Kong Stock Exchange and
     NASQAQ. The fair value was determined based on the closing price on the last trading day in the Reporting
     Period.

     ② Derivative financial assets represent foreign currency forward contracts, futures contracts and gains from
     unexpired contracts measured at fair value which were recognised as financial assets as at the balance sheet
     date.

(2) No restrictive financial asset measured at fair value through profit or loss was included in the closing balance.

(3) No hedging instruments in the closing balance and no hedging transactions have occurred during the period.

3. Notes receivable




                                                           210
       Joincare Pharmaceutical Group                                                                                                           Annual Report 2022


                                                    2022.12.31                                                              2021.12.31
      Category                                       Provision                                                             Provision
                          Book balance                for bad            Carrying amount            Book balance            for bad               Carrying amount
                                                       debts                                                                 debts
     Bank
     acceptance          1,959,985,016.85                    0.00          1,959,985,016.85       1,977,767,022.02         481,000.00               1,977,286,022.02
     bills

(1) Notes receivable pledged at year end

            Category                                                                                                            Amount pledged at year end
            Bank acceptance bills                                                                                                                  469,659,266.19


       As at 31 December 2022, bank acceptance bills with carrying amount of RMB469,659,266.19 (31 December
       2021: RMB870,153,979.75) have been used as pledge for opening of bills.

(2) Bills endorsed or discounted to other parties but not yet expired at balance sheet date

                                                                                  Amount derecognized at                 Amount not derecognized at year
                                    Category
                                                                                               year end                                              end
            Bank acceptance bills not yet mature but
                                                                                                542,620,475.62                                                   0.00
            already endorsed
            Bank acceptance bills not yet mature but
                                                                                                422,899,944.56                                                   0.00
            already discounted
                                     Total                                                      965,520,420.18                                                   0.00


       In the current period, the Company discounted bank acceptance bills of RMB1,089,259,970 (previous year:
       RMB76,908,320). Since the major risks and rewards such as interest rate risk related to these bank acceptance
       bills have been transferred to the bank, the Company derecognizes the discounted unexpired bank acceptance
       bills. Factoring expenses incurred was RMB6,363,470 (previous year: RMB506,780).

(3) There was no bills transferred into account receivables for non-performance by the issuer at balance sheet date
     of the period

(4) Disclosure by method of provision for bad debts

                                                2022.12.31                                                                        2021.12.31


 Category             Book balance             Provision for bad debts                                    Book balance               Provision for bad debts
                                                             Expected       Carrying value                                                         Expected      Carrying value
                                     Ratio
                   Amount                       Amount       credit loss                          Amount            Ratio (%)         Amount       credit loss
                                     (%)
                                                              rate (%)                                                                              rate (%)
 Provision
 for bad
 debts on                   0.00        0.00          0.00          0.00                0.00         481,000.00                 0.02 481,000.00        100.00                0.00
 individual
 item
 Including:
 Bank
 acceptance                 0.00        0.00          0.00          0.00                0.00         481,000.00                 0.02 481,000.00        100.00                0.00
 bills
 Provision
 for bad
 debts on        1,959,985,016.85     100.00          0.00          0.00     1,959,985,016.85   1,977,286,022.02            99.98          0.00           0.00    1,977,286,022.02
 portfolio
 basis
 Including:
 Bank
 acceptance      1,959,985,016.85     100.00          0.00          0.00     1,959,985,016.85   1,977,286,022.02            99.98          0.00           0.00    1,977,286,022.02
 bills
    Total        1,959,985,016.85     100.00          0.00          0.00     1,959,985,016.85   1,977,767,022.02           100.00 481,000.00              0.02    1,977,286,022.02


(5) Provision for bad debts on individual item:


                                                                                       211
     Joincare Pharmaceutical Group                                                                                                Annual Report 2022


                                                       2022.12.31                                                          2021.12.31
            Name                                Provision      Expected                                        Provision       Expected
                                 Book                                            Reason of       Book                                              Reason of
                                                 for bad       credit loss                                      for bad        credit loss
                                balance                                          provision      balance                                            provision
                                                  debts         rate (%)                                         debts          rate (%)
       Henan
       Jiuzhoutong                                                                                                                                Expected to be
                                        0.00           0.00             0.00                    431,000.00     431,000.00           100.00
       Pharmaceutical                                                                                                                              uncollectible
       Co., Ltd.
                                                                                                                                                 Expected to be
       Other customers                  0.00           0.00             0.00                     50,000.00      50,000.00           100.00
                                                                                                                                                  uncollectible
             Total                      0.00           0.00             0.00                    481,000.00     481,000.00           100.00

(6) Accrual, recovery or reversal of bad debt provision during the year

                     Item                                                      Amount of provision for bad debts
       Beginning balance                                                                                                                     481,000.00
       Provision for the year                                                                                                                      0.00
       Recovered or reversal in the
                                                                                                                                                   0.00
       year
       Write-off in the year                                                                                                                 481,000.00

               Closing balance                                                                                                                     0.00

 (7) Actual write-off of notes receivable during the year

                            Item                                                              Written-off amount
       Actual write-off of notes receivable                                                                                                  481,000.00

4. Accounts receivable

(1) Disclosure by ageing

                     Ageing                                           2022.12.31                                       2021.12.31
     Within one year                                                             3,120,189,972.55                                  2,872,710,981.81
     1 to 2 years (inclusive of 2 years)                                            23,444,432.08                                       18,541,236.06
     2 to 3 years (inclusive of 3 years)                                              3,734,160.84                                      12,869,985.75
     3 to 4 years (inclusive of 4 years)                                            12,774,996.94                                        7,835,031.26
     4 to 5 years (inclusive of 5 years)                                              2,294,804.48                                       1,332,259.38
     Over 5 years                                                                   13,796,669.97                                       12,807,886.92
                     Subtotal                                                    3,176,235,036.86                                  2,926,097,381.18
     Less: Provision for bad debts                                                  72,476,186.71                                       72,441,829.64
                        Total                                                    3,103,758,850.15                                  2,853,655,551.54
     According to the credit policy of the Company, the Company usually grants a credit period ranging from 30
     to 90 days to its customers.

(2) Disclosure by method of provision for bad debts

                                                  2022.12.31                                                          2021.12.31

                          Book balance          Provision for bad debts                         Book balance        Provision for bad debts
    Category
                                                                                                                                    Expected
                                                               Expected Carrying value                                                        Carrying value
                                        Ratio                                                                 Ratio                 credit
                         Amount                   Amount       credit loss                     Amount               Amount
                                        (%)                                                                   (%)                   loss rate
                                                                rate (%)
                                                                                                                                    (%)
    Provision for
                        10,454,599.67     0.33 6,257,914.47         59.86      4,196,685.20    9,709,854.02    0.33 5,513,168.82         56.78      4,196,685.20
    bad debts on


                                                                                212
     Joincare Pharmaceutical Group                                                                                                      Annual Report 2022


    individual
    item
    Including:
       Receivables
    from domestic   10,454,599.67 0.33 6,257,914.47                  59.86      4,196,685.20        9,709,854.02    0.33 5,513,168.82          56.78     4,196,685.20
    customers
       Receivables
    from overseas            0.00 0.00           0.00                 0.00                0.00              0.00    0.00            0.00        0.00             0.00
    customers
    Provision for
    bad debts on 3,165,780,437.19 99.67 66,218,272.24                 2.09 3,099,562,164.95 2,916,387,527.16 99.67 66,928,660.82                2.29 2,849,458,866.34
    portfolio basis
    Including:
       Receivables
    from domestic 2,659,276,844.47 83.72 60,180,304.43                2.26 2,599,096,540.04 2,333,938,533.50 79.76 58,705,544.56                2.52 2,275,232,988.94
    customers
       Receivables
    from overseas   506,503,592.72 15.95 6,037,967.81                 1.19    500,465,624.91      582,448,993.66 19.91 8,223,116.26             1.41   574,225,877.40
    customers
        Total        3,176,235,036.86 100.00 72,476,186.71            2.28 3,103,758,850.15 2,926,097,381.18 100.00 72,441,829.64               2.48 2,853,655,551.54


     Provision for bad debts on individual item:

                                                                                              Closing balance
                   Name                                               Provision for              Expected credit
                                            Book balance                                                                         Reason of provision
                                                                       bad debts                  loss rate (%)
                                                                                                                                Full amount is unlikely to be
       Purchase of goods                      10,454,599.67              6,257,914.47                       59.86
                                                                                                                                                   recovered

     Provision for bad debts on portfolio basis:

     Provision for bad debts on portfolio basis: Receivables from domestic customers

                                                        2022.12.31                                                         2021.12.31
            Ageing                                                              Expected
                                       Accounts          Provision for                               Accounts              Provision for       Expected credit
                                                                                credit loss
                                       receivable         bad debts                                  receivable             bad debts           loss rate (%)
                                                                                 rate (%)
    Within one year                  2,618,111,979.83     35,631,686.09                  1.36       2,290,261,988.15        32,953,674.70                 1.44
    1 to 2 years (inclusive
                                       18,418,832.08       3,486,917.81                 18.93         18,541,236.06          2,450,973.15                13.22
    of 2 years)
    2 to 3 years (inclusive
                                         3,589,415.19      2,144,629.72                 59.75           4,476,615.34         2,960,042.15                66.12
    of 3 years)
    3 to 4 years (inclusive
                                         4,381,626.53      4,171,620.14                 95.21           7,550,258.06         7,277,583.42                96.39
    of 4 years)
    4 to 5 years (inclusive
                                         1,667,403.89      1,637,863.72                 98.23           1,271,992.78         1,226,828.03                96.45
    of 5 years)
    Over 5 years                       13,107,586.95      13,107,586.95              100.00            11,836,443.11        11,836,443.11               100.00

             Total                   2,659,276,844.47     60,180,304.43                  2.26       2,333,938,533.50        58,705,544.56                 2.52

     Provision for bad debts on portfolio basis: Receivables from overseas customers

                                                         2022.12.31                                                        2021.12.31
                 Ageing                                                                                                                           Expected
                                        Accounts        Provision for        Expected credit          Accounts             Provision for bad
                                                                                                                                                  credit loss
                                        receivable       bad debts            loss rate (%)           receivable                 debts
                                                                                                                                                   rate (%)
       Within one year                 506,503,592.72    6,037,967.81                    1.19         582,448,993.66            8,223,116.26              1.41

                 Total                 506,503,592.72    6,037,967.81                    1.19         582,448,993.66            8,223,116.26              1.41


(3) Accrual, recovery or reversal of bad debt provision during the year

                              Item                                               Amount of provision for bad debts
       Beginning balance                                                                                                          72,441,829.64



                                                                                  213
     Joincare Pharmaceutical Group                                                                              Annual Report 2022


      Provision for the year                                                                                 2,978,050.82
      Recovered or reversal in the year                                                                              0.00
      Write-off in the year                                                                                  2,971,670.00
      Others                                                                                                   27,976.25

                  Closing balance                                                                         72,476,186.71
     At 31 December 2022 and 31 December 2021, the Company had no overdue but not impaired accounts
     receivable.

(4) Accounts receivable written-off during the year

                            Item                                                Written-off amount
      Actual written-off of accounts receivable                                                              2,971,670.00

(5) Accounts receivable due from the top five debtors

     As of 31 December 2022, the total amount of the top five debtors in closing balance is RMB380,564,636.45,
     accounting for 11.98% of the total amount of closing balance of accounts receivable, and the corresponding
     closing balance of provision for bad debts is total RMB3,048,053.17.

(6) There were no accounts receivable derecognized due to the transfer of financial assets in each reporting period.

(7) There were no assets or liabilities formed by the continuing involvement of transferred accounts receivables
     in each reporting period.

5. Prepayments

(1) Prepayments by ageing

                                             2022.12.31                                         2021.12.31
            Ageing
                                    Amount                  Ratio %                      Amount                   Ratio %
       Within one year               343,457,382.98                   94.29                 354,340,559.20              95.97
       1 to 2 years                   16,867,695.41                      4.63                 8,031,100.50                  2.17
       2 to 3 years                       948,519.54                     0.26                 6,323,201.42                  1.71
       Over 3 years                    2,991,544.64                      0.82                  537,685.17                   0.15
             Total                   364,265,142.57                 100.00                  369,232,546.29             100.00

(2) Prepayments due from the top five debtors:

     As of 31 December 2022, the total amount of the top five prepayments in closing balance is
     RMB127,433,641.24, accounting for 34.98% of the total amount of closing balance of prepayments.

6. Other receivables

                  Item                                2022.12.31                                     2021.12.31
      Interest receivable                                                       0.00                                365,873.64
      Other receivables                                            52,535,740.14                                  87,687,951.48
                 Total                                             52,535,740.14                                  88,053,825.12

(1) Other receivables

     ① by ageing


                                                                   214
Joincare Pharmaceutical Group                                                                               Annual Report 2022


                 Ageing                                      2022.12.31                                  2021.12.31
 Within one year                                                          46,704,835.62                                53,953,012.32

 1 to 2 years                                                                6,086,106.11                              33,803,432.35

 2 to 3 years                                                                2,206,852.09                               1,821,553.83
 3 to 4 years                                                                1,821,553.83                               2,532,015.23

 4 to 5 years                                                                1,816,535.04                                807,025.60

 Over 5 years                                                             32,171,819.98                                50,248,098.81

 Subtotal                                                                 90,807,702.67                            143,165,138.14
 Less: Provision for bad debts                                            38,271,962.53                                55,477,186.66

                   Total                                                  52,535,740.14                                87,687,951.48

② Disclosure by nature

                                          2022.12.31                                               2021.12.31
      Item                               Provision for       Carrying                              Provision for         Carrying
                    Book balance                                                Book balance
                                          bad debts          amount                                 bad debts            amount
 Security
 deposits,                                                                       11,003,281.04      2,897,272.69        8,106,008.35
                    12,668,692.36         3,613,600.49       9,055,091.87
 deposits and
 rental fees
 Reserved fund                                                                   17,870,245.40      2,259,346.33       15,610,899.07
                    25,494,468.62         2,952,756.24      22,541,712.38
 and advances
 Related party                                                                   20,328,583.96     19,068,538.71        1,260,045.25
                       1,097,855.07         477,066.07         620,789.00
 balances
 External
 entities           13,226,352.58        11,966,700.69       1,259,651.89        22,417,100.76     11,924,828.60       10,492,272.16
 balances
 Tax refund on                                                                   17,708,111.60        198,927.69       17,509,183.91
                    16,539,609.68           290,344.77      16,249,264.91
 exports
 Treasury
 bonds and                                                                       17,968,386.04     17,968,386.04                  0.00
                    17,968,386.04        17,968,386.04                0.00
 security
 deposits
 Capital                                                                         24,078,925.22              0.00       24,078,925.22
                                0.00              0.00                0.00
 reduction
 Amounts of
 exercised                      0.00              0.00                0.00        8,463,240.98              0.00        8,463,240.98
 options
 Others                3,812,338.32       1,003,108.23       2,809,230.09         3,327,263.14      1,159,886.60        2,167,376.54

     Total          90,807,702.67        38,271,962.53      52,535,740.14       143,165,138.14     55,477,186.66       87,687,951.48

③Information of provision for bad debts

At 31 December 2022, there is no provision for bad debts on those in first stage.

At year end, provision for bad debts on those in second stage:

                                                         Expected credit
                                                                           Provision for bad         Carrying
            Category                   Book balance      loss rate for the                                               Reason
                                                                                 debts               amount
                                                           lifetime(%)
Provision for bad debts on
                                                 0.00                 0.00                  0.00                0.00              --
individual item
Provision for bad debts on
                                        62,329,598.16              15.71           9,793,858.02     52,535,740.14
portfolio basis
  Export tax refund receivable          16,539,609.68                 1.76           290,344.77     16,249,264.91
  Security deposits, deposits           12,668,692.36              28.52           3,613,600.49       9,055,091.87


                                                                215
Joincare Pharmaceutical Group                                                                              Annual Report 2022


  and rental receivable

  Other receivables                33,121,296.12               17.78         5,889,912.76         27,231,383.36
            Total                  62,329,598.16               15.71         9,793,858.02         52,535,740.14

At year end, provision for bad debts on those in third stage:

                                                   Expected credit
                                                                        Provision for           Carrying
           Category              Book balance      loss rate for the                                               Reason
                                                                         bad debts              amount
                                                     lifetime(%)
Provision for bad debts on
                                 28,478,104.51                100.00      28,478,104.51                 0.00
individual item
                                                                                                               Not expected to
  Other receivables              28,478,104.51                100.00      28,478,104.51                 0.00
                                                                                                                be recoverable
Provision for bad debts on
                                          0.00                   0.00              0.00                 0.00                 --
portfolio basis
             Total               28,478,104.51                100.00      28,478,104.51                 0.00



As of 31 December 2021, information of provision for bad debts:

As of 31 December 2021, Provision for bad debts on those in first stage:

                                                       Expected
                                                    credit loss rate    Provision for          Carrying
           Category               Book balance                                                                     Reason
                                                     in the next 12      bad debts             amount
                                                      months (%)
Provision for bad debts on         32,542,166.20                 0.00             0.00         32,542,166.20
individual item
 Amounts of exercised options        8,463,240.98                0.00             0.00          8,463,240.98 Expected to be
                                                                                                               recovered
 Capital reduction                 24,078,925.22                 0.00             0.00         24,078,925.22 Expected to be
                                                                                                               recovered
Provision for bad debts on                   0.00                0.00             0.00                  0.00                 --
portfolio basis
              Total                32,542,166.20                 0.00             0.00         32,542,166.20

As of 31 December 2021, Provision for bad debts on those in second stage:

                                                    Expected credit
                                                                      Provision for bad           Carrying
          Category               Book balance       loss rate for the                                               Reason
                                                                            debts                 amount
                                                      lifetime(%)
Provision for bad debts on
                                            0.00                 0.00                   0.00                0.00             --
individual item
Provision for bad debts on
                                   63,594,020.80               13.28         8,448,235.52         55,145,785.28
portfolio basis
  Export tax refund receivable     17,708,111.60                 1.12          198,927.69         17,509,183.91
  Security deposits, deposits
                                   11,003,281.04               26.33         2,897,272.69          8,106,008.35
and rental receivable
  Other receivables                34,882,628.16               15.34         5,352,035.14         29,530,593.02

            Total                  63,594,020.80               13.28         8,448,235.52         55,145,785.28

As of 31 December 2021, Provision for bad debts on those in third stage:

                                                   Expected credit
                                                                        Provision for           Carrying
           Category              Book balance      loss rate for the                                               Reason
                                                                         bad debts              amount
                                                     lifetime(%)
Provision for bad debts on
                                 47,028,951.14                100.00      47,028,951.14                 0.00
individual item
                                                                                                               Not expected to
  Other receivables              47,028,951.14                100.00      47,028,951.14                 0.00
                                                                                                                be recoverable

                                                           216
Joincare Pharmaceutical Group                                                                                        Annual Report 2022


Provision for bad debts on
                                                0.00                    0.00                  0.00              0.00                     --
portfolio basis
              Total                47,028,951.14                    100.00        47,028,951.14                 0.00

④Accrual, recovery or reversal of bad debt provision during the year

                                           First stage             Second stage                  Third stage
                                                                                               Expected credit
    Provision for bad debts          Expected credit            Expected credit loss           loss for lifetime             Total
                                     loss within next          for lifetime (no credit              (credit
                                        12 months             impairment occurred)             impairment has
                                                                                                  occurred)
 Beginning balance                                     0.00               8,448,235.52               47,028,951.14        55,477,186.66
 Movement of beginning
 balance during the period
 --transfer to second stage                            0.00                         0.00                      0.00                   0.00
 --transfer to third stage                             0.00                    -42,585.00               42,585.00                    0.00
 --Reverse to second stage                             0.00                         0.00                      0.00                   0.00
 --Reverse to first stage                              0.00                         0.00                      0.00                   0.00
 Provision for the year                                0.00               1,304,163.32                        0.00         1,304,163.32
 Reversal in the year                                  0.00                         0.00               -158,470.77          -158,470.77
 Transfer in the year                                  0.00                         0.00                      0.00                   0.00
 Write-off in the year                                 0.00                138,045.77                18,434,960.86        18,573,006.63
 Other movement                                        0.00                222,089.95                         0.00           222,089.95

         Closing balance                               0.00               9,793,858.02               28,478,104.51        38,271,962.53

⑤Actual written-off of other receivables in the year

                        Item                                                     Written-off amount
 Actual written-off of other receivables                                             18,573,006.63

⑥Other receivables due from the top five debtors

                                                             Other                                                       Provision for
                                                                                                  Proportion to
                                                          receivables                                                     bad debts
        Name of entity                Nature                                     Ageing             total other
                                                            Closing                                                        Closing
                                                                                                 receivables (%)
                                                            balance                                                        balance
                                    Treasury
Hua Xia Securities Co., Ltd.        bonds and
                                                         17,968,386.04         Over 5 years                   19.79     17,968,386.04
(华夏证券股份有限公司)              security
                                    deposits
                                    Export tax                                  Within one
Tax refund on exports                                    16,539,609.68                                        18.21        290,344.77
                                    rebate                                            year
Guangzhou Yinhe Sunshine
Biological Products Co., Ltd.
(广州银河阳光生物制品有限           Loan                  5,000,000.00         Over 5 years                    5.51       5,000,000.00
公司)
People's Republic of China
Wanchai Customs (中华人民共         Security                                    Within one
                                                          1,271,801.36                                         1.40         12,718.01
                                    deposits                                          year
和国湾仔海关)
Suzhou Sino Promise Import &
Export Co., Ltd. (苏州中诺进        Security
                                                          1,200,000.00            1-2 years                    1.32         60,000.00
                                    deposits
出口有限公司)
              Total                                      41,979,797.08                                        46.23     23,331,448.82



                                                                 217
     Joincare Pharmaceutical Group                                                                                                        Annual Report 2022


     ⑦ There were no other receivables derecognised due to the transfer of financial assets in each reporting
     period.

     ⑧ There were no assets or liabilities formed by the continuing involvement of transferred other receivables
     in the period.

7. Inventories

(1) Inventories by category

                                                    2022.12.31                                                         2021.12.31
           Item
                                                     Provision for                                                     Provision for
                                 Book balance                          Carrying amount            Book balance                             Carrying amount
                                                   decline in value                                                  decline in value
    Raw materials               642,893,858.16       37,543,320.41          605,350,537.75       553,234,567.88        16,068,254.74         537,166,313.14

    Packaging materials         137,488,629.87       11,191,692.58          126,296,937.29       125,197,237.91          7,099,883.19        118,097,354.72
    Goods in process
    and Proprietary             649,362,917.78       65,482,989.52          583,879,928.26       538,151,968.97          2,891,675.04        535,260,293.93
    semi-finished goods
    Low-value
                                 80,473,347.95          495,743.41           79,977,604.54        61,806,078.47            217,760.90         61,588,317.57
    consumables
    Finished goods and
                              1,138,363,946.23       22,354,857.60     1,116,009,088.63          834,035,538.26        30,182,179.43         803,853,358.83
    stock goods
    Sub-contracting
                                  2,318,531.50                0.00            2,318,531.50          2,251,074.26                   0.00         2,251,074.26
    materials
    Consumptive
                                 13,692,837.04                0.00           13,692,837.04        12,342,303.96                    0.00       12,342,303.96
    biological assets
    Goods in transit             34,344,534.56                0.00           34,344,534.56          8,385,371.27                   0.00         8,385,371.27

           Total              2,698,938,603.09     137,068,603.52      2,561,869,999.57         2,135,404,140.98       56,459,753.30        2,078,944,387.68

     (2) Provision for decline in value of inventories

                                                                 Increase                                   Decrease
                Item                  2021.12.31                                                                                             2022.12.31
                                                                                                  Reversal or
                                                           Provision             Others                                  Others
                                                                                                  written-off
    Raw materials                     16,068,254.74         23,631,216.36              0.00           2,156,150.69                 0.00        37,543,320.41

    Packaging materials                 7,099,883.19         8,764,054.20              0.00           4,672,244.81                 0.00        11,191,692.58
    Goods in process and
    Proprietary semi-finished           2,891,675.04        63,112,373.68              0.00            521,059.20                  0.00        65,482,989.52
    goods
    Low-value consumables                217,760.90            289,387.02              0.00             11,404.51                  0.00           495,743.41
    Finished goods and stock
                                      30,182,179.43         24,913,820.98              0.00          32,741,142.81                 0.00        22,354,857.60
    goods
                Total                 56,459,753.30       120,710,852.24               0.00          40,102,002.02                 0.00       137,068,603.52


     Provision for decline in value of inventories (Continued)

                                                                                                                   Reason for reversal or written-off of
                                                     Basis in determination of net recoverable                  provision for decline in value of inventories/
                       Item
                                                   amount/residual value and cost to be incurred                   Provision for impairment of contract
                                                                                                                             performance cost
                                           The estimated selling price less the estimated costs of
       Raw materials                                                                                            Processing, sale of finished goods and discard
                                           completion, selling expenses and related taxes
                                           The estimated selling price less the estimated costs of
       Packaging materials                                                                                      Processing, sale of finished goods and discard
                                           completion, selling expenses and related taxes
       Goods in process and                The estimated selling price less the estimated costs of
                                                                                                                Processing of finished goods and discard
       Proprietary semi-finished goods     completion, selling expenses and related taxes
       Low-value consumables               The estimated selling price less the related taxes                   Used or discard
                                           The estimated selling price less the estimated selling
       Finished goods and stock goods                                                                           Sale and discard
                                           expenses and related taxes

(3) There was no capitalization of borrowing costs in the balance of inventories at the end of the period.

8. Non-current assets due within one year

                                                                                 218
     Joincare Pharmaceutical Group                                                                               Annual Report 2022


                          Item                                    2022.12.31                              2021.12.31

     Long-term receivables due within one year                                         0.00                            317,381.23
     Fixed deposits due within 1 year                                         54,048,611.11                                  0.00

                          Total                                               54,048,611.11                            317,381.23

9. Other current assets

                         Item                                   2022.12.31                                  2021.12.31
      Input VAT pending deduction /Input tax
                                                                              35,679,462.66                              53,179,328.86
     pending for verification
      Prepaid income tax                                                      17,665,709.39                              30,667,849.83
      Cash management                                                         92,815,738.44                                         0.00
      Return cost receivable                                                  12,043,428.52                                         0.00
      Others                                                                   5,335,561.31                                 139,035.68
                         Total                                               163,539,900.32                              83,986,214.37




10. Long-term receivables

(1) Long-term receivables by nature

                                               2022.12.31                                   2021.12.31
                                                                                                                            Range of
               Item                             Provision                                     Provision                     discount
                                   Book                       Carrying                                       Carrying
                                                 for bad                  Book balance         for bad                        rate
                                  balance                     amount                                         amount
                                                  debts                                         debts
       Financing lease
                                        0.00           0.00        0.00        584,285.36           0.00      584,285.36       4.75%
       payments
       Less: Long-term
       receivables due                  0.00           0.00        0.00        317,381.23           0.00      317,381.23
       within one year
               Total                    0.00           0.00        0.00        266,904.13           0.00      266,904.13

(2) There was no situation of overdue of long-term receivables in the period.

(3) There was no long-term receivables derecognized due to the transfer of financial assets in the period.

(4) There was no assets or liabilities formed by the continuing involvement of transferred long-term receivables in
the period.




                                                                   219
      Joincare Pharmaceutical Group                                                                                        Annual Report 2022




11. Long-term equity investment

                                                                                                                      Movement in the year
                                                                                                                                                                                                                            Closing balance of
                  Investee             2021.12.31                                                                                                              Announced                                  2022.12.31             provision for
                                                                                            Investment gain or                                                                      Provision
                                                           Additions in     Decrease in                         Adjustment in other      Changes of other     distribution of                                                     impairment
                                                                                             loss under equity                                                                         for      Others
                                                           investment       investment                         comprehensive income          equity          cash dividend or
                                                                                                  method                                                                           impairment
                                                                                                                                                                   profit
   ①Subsidiaries
   Zhongshan Renhe Health Products
   Co., Ltd. (中山市仁和保健品有限        6,337,823.35               0.00            0.00                0.00                   0.00                  0.00                  0.00        0.00       0.00      6,337,823.35      6,337,823.35
   公司)
   Guangzhou Hiyeah Industry Co.,
                                          1,949,893.45               0.00            0.00                0.00                   0.00                  0.00                  0.00        0.00       0.00      1,949,893.45      1,949,893.45
   Ltd. (广州市喜悦实业有限公司)

                  Subtotal                8,287,716.80               0.00            0.00                0.00                   0.00                  0.00                  0.00        0.00       0.00      8,287,716.80      8,287,716.80

   ②Associates
   Livzon Medical Electronic
   Equipment (Plant) Co., Ltd. (丽珠
                                          1,200,000.00               0.00            0.00                0.00                   0.00                  0.00                  0.00        0.00       0.00      1,200,000.00      1,200,000.00
   集团丽珠医用电子设备有限公
   司)
   Guangdong Blue Treasure
   Pharmaceutical Co. Ltd. (广东蓝       78,029,592.18               0.00            0.00       15,055,174.10                   0.00                  0.00                  0.00        0.00       0.00     93,084,766.28              0.00
   宝制药有限公司)
   Shenzhen City Youbao
   Technology Co., Ltd. (深圳市有         1,222,398.89               0.00            0.00         274,196.51                    0.00                  0.00                  0.00        0.00       0.00      1,496,595.40              0.00
   宝科技有限公司)
   AbCyte Therapeutics Inc.              15,154,709.96               0.00            0.00       -1,387,449.90                   0.00                  0.00                  0.00        0.00       0.00     13,767,260.06              0.00
   L&L Biopharma, Co. Ltd. (上海健
                                         14,886,838.46               0.00            0.00         -983,161.97                   0.00                  0.00                  0.00        0.00       0.00     13,903,676.49              0.00
   信生物医药科技有限公司)
   Zhuhai Sanmed Biotech Inc. (珠海
                                         83,155,557.16               0.00            0.00      -22,889,193.47             527,718.52            497,687.40                  0.00        0.00       0.00     61,291,769.61              0.00
   圣美生物诊断技术有限公司)
   Aetio Biotheraphy, Inc.               16,028,488.48               0.00            0.00            5,826.20                   0.00                  0.00                  0.00        0.00       0.00     16,034,314.68              0.00
   Jiangsu Atom Bioscience and
   Pharmaceutical Co., Ltd. (江苏新      67,908,607.98      30,000,000.00            0.00       -5,105,198.56                   0.00                  0.00                  0.00        0.00       0.00     92,803,409.42              0.00
   元素医药科技有限公司)
   Tianjin Tongrentang Group Co.,
   Ltd. (天津同仁堂集团股份有限         751,549,763.92               0.00            0.00       82,286,589.62            4,723,927.54                 0.00       111,980,000.00         0.00       0.00    726,580,281.08              0.00
   公司)
   Infinite Intelligence
   Pharmaceutical Co. Ltd. (北京英       19,937,909.64               0.00            0.00       -1,080,182.56                   0.00                  0.00                  0.00        0.00       0.00     18,857,727.08              0.00
   飞智药科技有限公司)
   Shenzhen Kangti Biomedical
   Technology Co., Ltd. (深圳康体生                 0.00     6,000,000.00            0.00                0.00                   0.00                  0.00                  0.00        0.00       0.00      6,000,000.00              0.00
   物医药科技有限公司)(Note 1)
   Jiaozuo Jinguan Jiahua Electric
   Power Co., Ltd. (焦作金冠嘉华电      284,619,909.01               0.00            0.00         918,586.51                    0.00                  0.00                  0.00        0.00       0.00    285,538,495.52              0.00
   力有限公司)




                                                                                                                220
   Joincare Pharmaceutical Group                                                                                                Annual Report 2022




                                                                                                                           Movement in the year
                                                                                                                                                                                                                                     Closing balance of
            Investee                   2021.12.31                                                                                                                   Announced                                    2022.12.31               provision for
                                                                                                 Investment gain or                                                                      Provision
                                                             Additions in        Decrease in                         Adjustment in other      Changes of other     distribution of                                                         impairment
                                                                                                  loss under equity                                                                         for      Others
                                                             investment          investment                         comprehensive income          equity          cash dividend or
                                                                                                       method                                                                           impairment
                                                                                                                                                                        profit
Ningbo Ningrong Biomedical Co.,
Ltd. (宁波宁融生物医药有限公             27,464,098.71                 0.00               0.00         -284,889.20                    0.00                 0.00                  0.00        0.00       0.00       27,179,209.51                0.00
司)
Feellife Health Inc. (深圳来福士
                                         12,734,373.22                 0.00               0.00        2,569,122.52                    0.00                 0.00                  0.00        0.00       0.00       15,303,495.74                0.00
雾化医学有限公司)
Novastage Pharmaceuticals
(Shenzhen) , Ltd. (新领医药技术          18,080,883.21                 0.00      18,080,883.21                0.00                    0.00                 0.00                  0.00        0.00       0.00                  0.00              0.00
(深圳) 有限公司)
Jiangsu Baining Yingchuang
Medical Technology Co., Ltd. (江         28,576,324.02                 0.00               0.00          156,057.09                    0.00                 0.00                  0.00        0.00       0.00       28,732,381.11                0.00
苏百宁盈创医疗科技有限公司)
Shanghai Sheo Pharmaceutical
Technology Co., Ltd. (上海偕怡                      0.00      17,000,000.00               0.00        2,309,212.61                    0.00                 0.00                  0.00        0.00       0.00       19,309,212.61                0.00
医药科技有限公司)(Note 2)

            Subtotal                   1,420,549,454.84       53,000,000.00      18,080,883.21       71,844,689.50            5,251,646.06           497,687.40       111,980,000.00         0.00       0.00     1,421,082,594.59       1,200,000.00

             Total                     1,428,837,171.64       53,000,000.00      18,080,883.21       71,844,689.50            5,251,646.06           497,687.40       111,980,000.00         0.00       0.00     1,429,370,311.39       9,487,716.80


   Note 1: On 30 September 2022, the Company's subsidiary, Zhuhai Livzon Pharmaceutical Equity Investment Management Co., Ltd. (珠海市丽珠医药股权投资管理有限公司) ("Equity Investment Company") and Shenzhen Kangti
   Biomedical Technology Co., Ltd. (深圳康体生物医药科技有限公司) (“Kangti Biomedical”) signed a shareholder agreement. Equity Investment Company invested RMB10 million to hold a 3.1746% shareholding in Kangti
   Biomedical (including the first phase of investment of RMB6 million). According to the shareholder agreement and the articles of association, Equity Investment Company appointed a director to Kangti Biomedical. Since Equity
   Investment Company is able to exercise significant influence over Kangti Biomedical, the investment in Kangti Biomedical is accounted for as a long-term equity investment.

   Note 2: On April 22, 2022, Shanghai Frontier Health Pharmaceutical Technology Co., Ltd. (上海方予健康医药科技有限公司) ("Shanghai Frontier") ,a subsidiary of the Company, acquired 20% of the equity of Shanghai Sheo
   Pharmaceutical Technology Co., Ltd. (上海偕怡医药科技有限公司) (“Shanghai Sheo”) from the original shareholders for RMB7 million; On October 28, 2022, the Company signed a capital increase agreement with Shanghai Sheo,
   investing RMB10 million to hold 10% of the equity of Shanghai Sheo. After the company's investment, the stake of the Shanghai Frontier will be reduced to 17.999%.




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12. Other equity instruments investment

                                                                                                              Reason for
                           Item                               2022.12.31            2021.12.31
                                                                                                              designation
     China Galaxy Securities Co., Ltd. (中国银河证券
                                                                           0.00          212,384,666.97          Non-trading
     股份有限公司)
     Shanghai Yunfeng Xinchuang Equity Investment
                                                                 67,935,704.36            94,040,236.88          Non-trading
     Center (上海云锋新创股权投资中心)
     Shanghai JingYi Investment Center (上海经颐投
                                                                 73,616,359.91            66,175,062.50          Non-trading
     资中心)
     Qianhai Equity Investment Fund (前海股权投资
                                                                243,378,742.17           264,930,500.00          Non-trading
     基金)
     Apricot Forest, Inc (杏树林)                               120,788,500.00           137,711,800.01          Non-trading
     PANTHEON D ,L.P.                                             5,954,301.20             3,715,566.69          Non-trading
     Zhuhai China Resources Bank Co., Ltd. (珠海华
                                                                158,400,000.00           164,395,200.00          Non-trading
     润银行股份有限公司)
     GLOBAL HEALTH SCIENCE                                      271,980,388.15           235,133,216.46          Non-trading
     Nextech V Oncology S.C.S., SICAV-SIF                        23,996,121.32            30,667,263.04          Non-trading
     Yizun Biopharmaceutics (Shanghai) Co., Ltd. (羿
                                                                 30,513,209.27            59,999,953.41          Non-trading
     尊生物医药(上海) 有限公司)
     ELICIO THERAPEUTICS, INC.                                   34,823,014.36            31,878,510.16          Non-trading
     CARIAMA THER APEUTICS INC.                                  34,821,295.50            31,876,936.63          Non-trading
     Beijing Luzhu Biotechnology Co., Ltd. (北京绿竹
                                                                 53,654,738.60            41,944,015.67          Non-trading
     生物技术股份有限公司)
     Shanghai Keentai Biotechnology Co., Ltd. (上海
                                                                 12,000,000.00            12,000,000.00          Non-trading
     科恩泰生物医药科技有限公司)
     Others                                                      62,096,504.21            22,029,449.00          Non-trading

                           Total                              1,193,958,879.05         1,408,882,377.42

     Continued:

                                                                                              Amount
                                                                                          transferred from
                                        Dividend income
                                                                          Cumulative            other            Reason of
                  Item                  recognised in the Cumulative gain
                                                                             loss          comprehensive          transfer
                                              year
                                                                                         income to retained
                                                                                              earnings
    China Galaxy Securities Co., Ltd.
                                                       0.00            0.00       0.00        94,089,666.09          Disposal
    (中国银河证券股份有限公司)
    Shanghai Yunfeng Xinchuang
    Equity Investment Center (上海云                   0.00            0.00       0.00        -4,367,599.87         Disposal-
    锋新创股权投资中心)
    Shanghai JingYi Investment
                                              512,350.35               0.00       0.00                 0.00                  --
    Center (上海经颐投资中心)
    Qianhai Equity Investment Fund
                                            13,160,623.21              0.00       0.00                 0.00                  --
    (前海股权投资基金)
    Apricot Forest, Inc (杏树林)                       0.00            0.00       0.00                 0.00                  --

    PANTHEON D ,L.P.                                   0.00            0.00       0.00                 0.00                  --
    Zhuhai China Resources Bank
    Co., Ltd. (珠海华润银行股份有                      0.00            0.00       0.00                 0.00                  --
    限公司)
    GLOBAL HEALTH SCIENCE                    3,956,817.66              0.00       0.00                 0.00                  --
    Nextech V Oncology S.C.S.,               1,053,846.01              0.00       0.00                 0.00                  --
    SICAV-SIF



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     Joincare Pharmaceutical Group                                                                       Annual Report 2022


                                                                                               Amount
                                                                                           transferred from
                                             Dividend income
                                                                               Cumulative        other            Reason of
                    Item                     recognised in the Cumulative gain
                                                                                  loss      comprehensive          transfer
                                                   year
                                                                                          income to retained
                                                                                               earnings
    Yizun Biopharmaceutics
    (Shanghai) Co., Ltd. (羿尊生物医                      0.00           0.00           0.00             0.00                  --
    药(上海) 有限公司)
    ELICIO THERAPEUTICS, INC.                             0.00           0.00           0.00             0.00                  --
    CARIAMA THER APEUTICS                                 0.00           0.00           0.00             0.00                  --
    INC.
    Beijing Luzhu Biotechnology Co.,
    Ltd. (北京绿竹生物技术股份有                          0.00           0.00           0.00             0.00                  --
    限公司)
    Shanghai Keentai Biotechnology
    Co., Ltd. (上海科恩泰生物医药                         0.00           0.00           0.00             0.00                  --
    科技有限公司)
    Others                                           30,000.00           0.00           0.00             0.00                  --

                    Total                        18,713,637.23           0.00           0.00    89,722,066.22                  --




13. Investment properties

                                                                           Housing and
                                      Item                                                              Total
                                                                            buildings
      I. Book value
          1. Beginning balance                                                  61,914,754.28                  61,914,754.28
          2.Increase                                                                     0.00                           0.00
          3.Decrease                                                                     0.00                           0.00
          4.Closing balance                                                     61,914,754.28                  61,914,754.28
      II. Accumulated depreciation and amortisation
             1.Beginning balance                                                55,723,278.85                  55,723,278.85
             2.Increase                                                                  0.00                           0.00
          (1) Amortisation for the year                                                  0.00                           0.00
             3.Decrease                                                                  0.00                           0.00
          (1) Disposal                                                                   0.00                           0.00
             4. Closing balance                                                 55,723,278.85                  55,723,278.85
      III. Provision for impairment                                                      0.00                           0.00
             1.Beginning balance                                                         0.00                           0.00
             2.Increase                                                                  0.00                           0.00
          (1) Provision                                                                  0.00                           0.00
             3. Decrease                                                                 0.00                           0.00
             (1) Disposal                                                                0.00                           0.00
             4.Closing balance                                                           0.00                           0.00
      IV. Carrying amount
          1.Carrying value at year end                                           6,191,475.43                   6,191,475.43
          2.Carrying value at beginning of year                                  6,191,475.43                   6,191,475.43


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14. Fixed assets

                           Item                                    2022.12.31                                  2021.12.31
            Fixed assets                                                        5,265,200,110.91                  4,839,005,169.81
            Fixed assets for disposal                                                       0.00                                 0.00
                           Total                                                5,265,200,110.91                  4,839,005,169.81

     (1) Fixed assets

          ①Details of fixed assets

                                                                                          Electronic
                                         Housing and       Machinery and
                       Item                                              Motor vehicles equipment and             Total
                                          buildings         equipment
                                                                                            others
          I. Book value:
          1.Beginning balance           3,976,199,210.91 5,119,816,758.02 108,015,330.21 783,366,162.98 9,987,397,462.12
          2.Increase                     342,127,376.83     628,876,021.14   6,461,652.11   97,012,190.24 1,074,477,240.32
          (1) Purchase                    65,441,049.18     147,389,281.70   5,280,741.59   58,931,934.55      277,043,007.02
          (2) Transfer from
                                         276,686,327.65     481,486,739.44           0.00   15,719,395.68      773,892,462.77
          construction in progress
          (3) Others                               0.00               0.00   1,180,910.52   22,360,860.01        23,541,770.53
          3.Decrease                      13,272,568.72     111,148,294.43   8,185,405.44   23,825,880.16      156,432,148.75
          (1) Disposal or scrap           13,272,568.72     111,148,294.43   8,185,405.44   23,825,880.16      156,432,148.75
          4.Closing balance             4,305,054,019.02 5,637,544,484.73 106,291,576.88 856,552,473.06 10,905,442,553.69
          II. Accumulated
                                                       -                 -              -                  -                 -
          depreciation
          1.Beginning balance           1,633,263,266.38 2,850,461,052.50 76,499,140.97 478,176,262.36 5,038,399,722.21
          2.Increase                     181,477,081.95     346,324,779.03 10,462,940.46    81,920,529.52      620,185,330.96
          (1) Provision                  181,477,081.95     346,324,779.03   9,296,030.33   81,920,529.52      619,018,420.83
          (2) Other increase                       0.00               0.00   1,166,910.13               0.00      1,166,910.13
          3.Decrease                       7,852,119.16      86,818,439.43   4,791,950.88   21,842,549.49      121,305,058.96
          (1) Disposal or scrap            7,852,119.16      86,818,439.43   4,791,950.88   21,842,549.49      121,305,058.96
          4.Closing balance             1,806,888,229.17 3,109,967,392.10 82,170,130.55 538,254,242.39 5,537,279,994.21
          III. Provision for
                                                       -                 -              -                  -                 -
          impairment
          1.Beginning balance             26,564,784.45      64,186,228.26      41,578.65   19,199,978.74      109,992,570.10
          2.Increase                               0.00         161,670.35           0.00          24,878.03       186,548.38
          (1) Provision                            0.00         161,670.35           0.00          24,878.03       186,548.38
          3.Decrease                          90,292.62       6,798,397.52      41,578.65      286,401.12         7,216,669.91
          (1) Disposal or scrap               90,292.62       6,798,397.52      41,578.65      286,401.12         7,216,669.91
          4.Closing balance               26,474,491.83      57,549,501.09           0.00   18,938,455.65      102,962,448.57
          IV. Carrying amount                          -                 -              -                  -                 -
          1. Carrying value at
                                        2,471,691,298.02 2,470,027,591.54 24,121,446.33 299,359,775.02 5,265,200,110.91
          period end
          2. Carrying value at
                                        2,316,371,160.08 2,205,169,477.26 31,474,610.59 285,989,921.88 4,839,005,169.81
          beginning of year




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     ②Fixed assets with temporary idle

                                                                 Accumulated                   Provision for
                Item                    Book value                                                                 Carrying amount           Note
                                                                 depreciation                  impairment
      Housing and buildings              23,926,279.99                  14,490,518.30             5,155,770.80            4,279,990.89
      Machinery and
                                        169,656,887.40              117,171,435.61               35,728,561.41          16,756,890.38
      equipment
      Electronic equipment
                                           3,119,826.93                  2,533,159.51               180,534.90              406,132.52
      and others
                Total                   196,702,994.32              134,195,113.42               41,064,867.11          21,443,013.79

     ③Fixed assets held under finance leases

                                       Item                                                               Carrying amount
      Housing and buildings                                                                                                              1,753,301.29

     ④Fixed assets without property certificate

                             Item                                  Carrying amount                       Reasons for pending title certificate
      Housing and buildings                                                       182,318,779.85                             Application in progress

15. Construction in progress

                     Item                                        2022.12.31                                           2021.12.31
      Construction in progress                                                810,835,273.97                                        742,533,534.23
      Construction materials                                                        464,794.99                                          465,209.52
                     Total                                                    811,300,068.96                                        742,998,743.75



     ① Information of construction in progress

                                                           2022.12.31                                              2021.12.31
                  Item
                                                           Provision for                                           Provision for
                                         Book balance                       Net book value         Book balance                       Net book value
                                                            impairment                                              impairment
     Haibin Pharma Pingshang New
                                        133,771,969.05 11,068,266.54        122,703,702.51        144,364,877.42          0.00        144,364,877.42
     Factory (深圳海滨坪山新厂)
     Guangda New Factory Project        360,963,893.27             0.00     360,963,893.27        179,745,064.48          0.00        179,745,064.48
     Fuxing Company Phase I & II
     Projects and others (福兴公司I.     38,842,449.73             0.00      38,842,449.73         36,580,114.83          0.00         36,580,114.83
     二期项目及其他)
     Project of Shijiao New Factory
                                         12,409,895.73             0.00      12,409,895.73         61,845,397.73          0.00         61,845,397.73
     (石角新厂项目)
     Transformation Project of
     Pharmaceutical Factory              70,972,186.23             0.00      70,972,186.23         19,579,452.17          0.00         19,579,452.17
     Workshop (药厂车间建设项目)
     Construction Project for
     Microsphere Workshop
     (including Gose) of Livzon
     Group Livzon Pharmaceutical         39,976,590.91             0.00      39,976,590.91         15,616,651.12          0.00         15,616,651.12
     Factory (丽珠制药厂) 微球车间
     (含戈舍) 建设项目)
     P06 Construction Project of
     Livzon Group Livzon
                                              180,053.79           0.00         180,053.79         83,020,966.01          0.00         83,020,966.01
     Pharmaceutical Factory (丽珠制
     药厂) P06建设项目)
     Project of lyophilized powder
     injection workshop (冻干粉针车       1,157,559.47             0.00       1,157,559.47         70,673,332.62          0.00         70,673,332.62
     间项目)
     P09 Construction Project of
                                                    0.00           0.00                 0.00       54,924,595.61          0.00         54,924,595.61
     Livzon Group Livzon


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         Joincare Pharmaceutical Group                                                                                                        Annual Report 2022


                                                                   2022.12.31                                                 2021.12.31
                       Item
                                                                   Provision for                                              Provision for
                                                 Book balance                      Net book value             Book balance                           Net book value
                                                                    impairment                                                 impairment
         Pharmaceutical Factory (丽珠制
         药厂) P09建设项目)
         P04/P05 Construction Project of
         Livzon Group Livzon
                                                  1,560,960.52             0.00         1,560,960.52            257,441.66             0.00              257,441.66
         Pharmaceutical Factory (丽珠制
         药厂) P04/P05建设项目)
         Shanghai Livzon-Microsphere
         Phase II Technical
                                                 34,677,843.69             0.00      34,677,843.69            10,123,776.54            0.00           10,123,776.54
         Transformation Project (上海丽
         珠-微球二期技改项目)
         Others                                 127,559,478.58       169,340.46    127,390,138.12             65,971,204.50    169,340.46             65,801,864.04

                       Total                    822,072,880.97 11,237,607.00       810,835,273.97         742,702,874.69       169,340.46            742,533,534.23


         ②Changes in significant construction in progress

                                                                                                                     Including:        Interest
                                                                                                         Cumulativ
                                                                                                                       interest       capitalisati
                                                                    Transfer to fixed                     e amount
   Name of Project             2021.12.31          Increase                               Other decrease              capitalise      on rate for      2022.12.31
                                                                         assets                          of interest
                                                                                                                       d in the        the year
                                                                                                         capitalised
                                                                                                                         year            (%)
Haibin Pharma
Pingshang New Factory          144,364,877.42 218,228,529.86            164,393,809.16      64,427,629.07           0.00       0.00           0.00     133,771,969.05
(深圳海滨坪山新厂)
Guangda New Factory
                               179,745,064.48 181,218,828.79                       0.00                0.00         0.00       0.00           0.00     360,963,893.27
Project (光大新厂项目)
Fuxing Company Phase
I & II Projects and
                                36,580,114.83      77,051,711.32         74,789,376.42                 0.00         0.00       0.00           0.00      38,842,449.73
others (福兴公司一、
二期项目及其他)
Project of Shijiao New
Factory (石角新厂项             61,845,397.73      30,318,359.71         79,753,861.71                 0.00         0.00       0.00           0.00      12,409,895.73
目)
Transformation Project
of Pharmaceutical
Factory Workshop (药            19,579,452.17      70,984,195.20         19,591,461.14                 0.00         0.00       0.00           0.00      70,972,186.23
厂车间建设项目)
Construction Project for
Microsphere Workshop
(including Gose) of
Livzon Group Livzon
Pharmaceutical Factory          15,616,651.12      29,308,744.91          4,948,805.12                 0.00         0.00       0.00           0.00      39,976,590.91
(丽珠集团丽珠制药厂
微球车间(含戈舍) 建
设项目)
P06 Construction
Project of Livzon Group
Livzon Pharmaceutical           83,020,966.01       7,323,839.40         90,164,751.62                 0.00         0.00       0.00           0.00        180,053.79
Factory (丽珠集团丽珠
制药厂 P06 建设项目)
Project of lyophilized
powder injection
                                70,673,332.62      49,803,364.24        119,319,137.39                 0.00         0.00       0.00           0.00       1,157,559.47
workshop 冻干粉针车
间项目)
P09 Construction
Project of Livzon Group
Livzon Pharmaceutical           54,924,595.61      99,318,116.09        154,242,711.70                 0.00         0.00       0.00           0.00               0.00
Factory (丽珠集团丽珠
制药厂 P09 建设项目)
P04/P05 Construction
Project of Livzon Group
Livzon Pharmaceutical
Factory (丽珠集团丽珠              257,441.66       1,303,518.86                   0.00                0.00         0.00       0.00           0.00       1,560,960.52
制药厂 P04/P05 建设项
目)
Technology
transformation project
                                10,123,776.54      24,554,067.15                   0.00                0.00         0.00       0.00           0.00      34,677,843.69
for Microsphere Phase
II of Shanghai Livzon



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                                                                                                             Including: Interest
                                                                                                 Cumulativ
                                                                                                               interest capitalisati
                                                            Transfer to fixed                     e amount
   Name of Project         2021.12.31        Increase                             Other decrease              capitalise on rate for    2022.12.31
                                                                 assets                          of interest
                                                                                                               d in the   the year
                                                                                                 capitalised
                                                                                                                 year       (%)
(上海丽珠微球二期技
改项目)
Others                       65,971,204.50 151,152,406.67        66,688,548.51      22,875,584.08        0.00       0.00        0.00    127,559,478.58

         Total              742,702,874.69 940,565,682.20      773,892,462.77       87,303,213.15        0.00       0.00        0.00    822,072,880.97


         Changes in significant construction in progress (Continued) :

                                                                            Proportion of
                 Name of Project                        Budget            cumulative input          Progress %                Source of fund
                                                                            to budget %
         Haibin Pharma Pingshang New                                                                 Completion of         Self-funding and funds
                                               1,037,000,000.00                           78.1       some projects                         raised
         Factory (深圳海滨坪山新厂)
         Guangda New Factory Project (光大
                                                 646,000,000.00                         55.88 Under construction                       Self-funding
         新厂项目)
         Fuxing Company Phase I & II Projects
                                                                                                     Completion of
         and others (福兴公司一、二期项目        378,090,800.00                         87.45                                          Self-funding
                                                                                                     some projects
         及其他)
         Project of Shijiao New Factory (石角                                                        Completion of         Self-funding and funds
                                                 377,005,000.00                         89.92
         新厂项目)                                                                                   some projects                         raised
         Transformation Project of
                                                                                                     Completion of
         Pharmaceutical Factory Workshop (药 306,558,388.48                             61.17                                          Self-funding
                                                                                                     some projects
         厂车间建设项目)
         Construction Project for Microsphere
         Workshop (including Gose) of Livzon
         Group Livzon Pharmaceutical Factory 262,445,000.00                                          Completion of         Self-funding and funds
                                                                                        65.12        some projects                         raised
         (丽珠集团丽珠制药厂微球车间(含
         戈舍) 建设项目)
         P06 Construction Project of Livzon
         Group Livzon Pharmaceutical Factory                                                         Completion of
                                                 117,710,000.00                         95.02                                          Self-funding
         (丽珠集团丽珠制药厂 P06 建设项                                                              some projects
         目)
         Project of lyophilized powder
                                                                                                     Completion of         Self-funding and funds
         injection workshop (冻干粉针车间项 143,500,000.00                              95.11        some projects                         raised
         目)
         P09 Construction Project of Livzon
         Group Livzon Pharmaceutical Factory 296,580,000.00                            100.00            Completed                     Self-funding
         (丽珠丽珠制药厂 P09 建设项目)
         P04/P05 Construction Project of
         Livzon Group Livzon Pharmaceutical
         Factory (丽珠集团丽珠制药厂             126,880,000.00                           1.23 Under construction                      Self-funding
         P04/P05 建设项目)
         Technology transformation project for
         Microsphere Phase II of Shanghai
         Livzon (上海丽珠微球二期技改项           40,500,000.00                         85.62 Under construction                       Self-funding
         目)
          Others                                                     --                      --                     --                 Self-funding
                           Total                   3,732,269,188.48                          --                     --                            --

         Other decrease is mainly transferred to long-term deferred expenses.

 16. Right-of-use assets

                         Item                                 Housing and buildings                                           Total
         I. Book value:



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                             Item                                 Housing and buildings                                  Total
                 1.Beginning balance                                                      69,960,518.27                          69,960,518.27
                 2.Increase                                                               29,002,437.68                          29,002,437.68
                 (1) Leasing                                                              29,002,437.68                          29,002,437.68
                 3.Decrease                                                               20,627,100.42                          20,627,100.42
                 4. Closing balance                                                       78,335,855.53                          78,335,855.53
           II. Accumulated depreciation
                 1.Beginning balance                                                      23,185,758.58                          23,185,758.58
                 2.Increase                                                               32,367,074.98                          32,367,074.98
                 (1) Provision                                                            32,367,074.98                          32,367,074.98
                 3.Decrease                                                               19,060,112.00                          19,060,112.00
                 4.Closing balance                                                        36,492,721.56                          36,492,721.56
           III. Provision for impairment
                 1.Beginning balance                                                               0.00                                      0.00
                 2.Increase                                                                        0.00                                      0.00
                 3.Decrease                                                                        0.00                                      0.00
                 4.Closing balance                                                                 0.00                                      0.00
           IV. Carrying amount
                 1.Carrying value at year
                                                                                          41,843,133.97                          41,843,133.97
           end
                2.Carrying value at
                                                                                          46,774,759.69                          46,774,759.69
           beginning of year

           As of 31 December 2022, the Company recognised lease expenses related to short-term leases and the leases
           of low value assets of RMB239,280.

17. Intangible assets

     (1) Details of intangible assets

                                                           Patent and                         Trademark
                 Item               Land use rights                           Software                          Others               Total
                                                       technical know-how                       rights
        I. Book value

          1.Beginning balance         413,762,737.87       519,813,876.67    79,232,390.69    62,769,716.98   10,985,294.53      1,086,564,016.74

          2.Increase                   28,488,823.32       496,141,693.87    14,020,493.45             0.00            0.00       538,651,010.64

          (1) Purchase                 28,488,823.32          1,100,000.00   14,020,493.45             0.00            0.00        43,609,316.77

          (2) Internal R&D                      0.00       495,041,693.87             0.00             0.00            0.00       495,041,693.87

          3.Decrease                            0.00                  0.00            0.00             0.00            0.00                   0.00

         Disposal                               0.00                  0.00            0.00             0.00            0.00                   0.00

        4.Closing balance             442,251,561.19      1,015,955,570.54   93,252,884.14    62,769,716.98   10,985,294.53      1,625,215,027.38
        II. Accumulated
        amortisation
          1.Beginning balance         122,997,170.29       369,635,517.03    56,287,892.35    62,765,196.55    5,584,191.37       617,269,967.59

          2.Increase                    9,122,311.45       172,774,379.26     7,114,468.80          471.72     1,098,529.45       190,110,160.68

               Provision                9,122,311.45       172,774,379.26     7,114,468.80          471.72     1,098,529.45       190,110,160.68

          3.Decrease                            0.00                  0.00            0.00             0.00            0.00                   0.00




                                                                             228
          Joincare Pharmaceutical Group                                                                                    Annual Report 2022


                                                      Patent and                              Trademark
                 Item          Land use rights                            Software                                Others            Total
                                                  technical know-how                            rights
         Disposal                          0.00                 0.00               0.00                0.00             0.00                0.00

         4.Closing balance       132,119,481.74       542,409,896.29     63,402,361.15        62,765,668.27      6,682,720.82     807,380,128.27
       III. Provision for
       impairment
         1.Beginning balance         981,826.94        11,530,127.41               0.00                0.00             0.00       12,511,954.35

         2.Increase                        0.00         3,207,819.01               0.00                0.00             0.00        3,207,819.01

               Provision                   0.00         3,207,819.01               0.00                0.00             0.00        3,207,819.01

         3.Decrease                        0.00                 0.00               0.00                0.00             0.00                0.00

         4.Closing balance           981,826.94        14,737,946.42               0.00                0.00             0.00       15,719,773.36

       IV. Carrying amount
         1.Carrying value at
                                 309,150,252.51       458,807,727.83     29,850,522.99             4,048.71      4,302,573.71     802,115,125.75
       year end
         2.Carrying value at
                                 289,783,740.64       138,648,232.23     22,944,498.34             4,520.43      5,401,103.16     456,782,094.80
       beginning of year

          As of 31 December 2022, intangible assets formed through internal research and development of the
          company account for 39.03% of the balance of intangible assets.

          At the balance sheet date, the Company engaged an appraiser to test the impairment of biopharmaceutical
          technologies of the current period carry-over intangible assets, using the biotechnology-related asset group
          to estimate the present value of future cash flows in anticipation of the recoverable amount of input costs.
          The asset group was tested as not impaired.

          The projected future cash flows of the asset group are determined on the basis of the financial budget for the
          next five years established by management, and the cash flow for the years beyond which the five-year
          financial budget is zero.

          The main assumptions of discounted future cash flows in the impairment test are as follows:

          The calculation of the projected present future cash flow value of the asset group related to this biotechnology
          uses a gross margin of 84.50%-91.50% and an operating income growth rate of -93%~71%, and a discount
          cash flow rate of 15.00% as key assumptions. Management determines these assumptions based on historical
          conditions prior to the budget period and projections of market developments.

    (2) Intangible assets pending for certificates of ownership

                                 Item                              Carrying amount                 Reasons for pending title certificate
           Land use rights                                                     4,012,089.17                             Application in progress

    (3) Intangible assets

          The land use rights represent the state-owned land use rights obtained by the Company in accordance with
          PRC laws in China, and the term of grant will be 50 years commencing from the date of obtaining the land
          use rights

18. Development costs

                                                              Increase                                Decrease
                    Item          2021.12.31               Internal                 Recognized as              Recognised in      2022.12.31
                                                                             Other
                                                       development                     intangible             profit or loss in
                                                                           increase
                                                              costs                        assets                     the year
           Chemical
                                179,411,666.34        99,354,717.46              0.00     75,078,369.10        66,830,198.83      136,857,815.87
           pharmaceuticals
           Biologics            527,275,067.73        92,785,310.25              0.00 381,832,741.41                       0.00   238,227,636.57



                                                                         229
     Joincare Pharmaceutical Group                                                                                            Annual Report 2022


     APIs and others            80,306,701.64         11,023,313.45                 0.00    38,130,583.36                     0.00       53,199,431.73
            Total             786,993,435.71        203,163,341.16                  0.00 495,041,693.87           66,830,198.83        428,284,884.17

    Continued:

                                 Time for commencement                                                            Progress of research and
               Item                                                    Specific basis of capitalisation
                                    of capitalisation                                                             development at year end
     Chemical
                                                   Clinical trial         Obtain approval for clinical trial                         Clinical stage
     pharmaceuticals
     Biologics                                     Clinical trial         Obtain approval for clinical trial                         Clinical stage
     APIs and others                                 Pilot stage                    Pilot related information                    Post-pilot stage

19. Goodwill

(1) Book value of goodwill

                                                                                           Increase                 Decrease
      Name of investee or matter from which goodwill
                                                              2021.12.31         Formation by                                             2022.12.31
                           arose                                                                                 Disp
                                                                                   business           Others             Others
                                                                                                                 osal
                                                                                 combination
      Shanghai Livzon Pharmaceutical Manufacturing
                                                                2,045,990.12               0.00          0.00     0.00        0.00           2,045,990.12
      Co., Ltd. (上海丽珠制药有限公司)
      Zhuhai FTZ Livzon Hecheng Pharmaceutical
      Manufacturing Co., Ltd. (珠海保税区丽珠合成制             3,492,752.58               0.00          0.00     0.00        0.00           3,492,752.58
      药有限公司)
      Sichuan Guangda Pharmaceutical Manufacturing
                                                               13,863,330.24               0.00          0.00     0.00        0.00          13,863,330.24
      Co., Ltd. (四川光大制药有限公司)
      Livzon Group Xinbeijiang Pharmaceutical
      Manufacturing Inc. (丽珠集团新北江制药股份有              7,271,307.03               0.00          0.00     0.00        0.00           7,271,307.03
      限公司)
      Livzon Group Fuzhou Fuxing Pharmaceutical Co.,
                                                               46,926,155.25               0.00          0.00     0.00        0.00          46,926,155.25
      Ltd. (丽珠集团福州福兴医药有限公司)
      Livzon Group Livzon Pharmaceutical Factory (丽珠
                                                               47,912,269.66               0.00          0.00     0.00        0.00          47,912,269.66
      制药厂)
      Livzon Group                                           395,306,126.41                0.00          0.00     0.00        0.00         395,306,126.41
      Shenzhen Haibin Pharmaceutical Co., Ltd. (深圳市
                                                               91,878,068.72               0.00          0.00     0.00        0.00          91,878,068.72
      海滨制药有限公司)
      Joincare Daily-Use & Health Care Co., Ltd. (健康
                                                                1,610,047.91               0.00          0.00     0.00        0.00           1,610,047.91
      元日用保健品有限公司)
      Shenzhen Taitai Pharmaceutical Co., Ltd. (深圳太
                                                                    635,417.23             0.00          0.00     0.00        0.00            635,417.23
      太药业有限公司)
      Health Pharmaceuticals (China) Limited (健康药业
                                                               23,516,552.65               0.00          0.00     0.00        0.00          23,516,552.65
      (中国) 有限公司)
      Shenzhen Hiyeah Industry Co., Ltd (深圳市喜悦实
                                                                6,000,000.00               0.00          0.00     0.00        0.00           6,000,000.00
      业有限公司)
      Jiaozuo Joincare Bio Technological Co., Ltd. (焦作
                                                                     92,035.87             0.00          0.00     0.00        0.00              92,035.87
      健康元生物制品有限公司)
                            Total                            640,550,053.67                0.00          0.00     0.00        0.00         640,550,053.67

(2) Provision for impairment of goodwill

                                                                                            Increase               Decrease
       Name of investee or matter from which goodwill
                                                                2021.12.31                                                                 2022.12.31
                            arose                                                                               Dispos
                                                                                     Provision    Others                 Others
                                                                                                                  al
      Livzon Group Xinbeijiang Pharmaceutical
      Manufacturing Inc. (丽珠集团新北江制药股份有限                 7,271,307.03          0.00         0.00      0.00        0.00           7,271,307.03
      公司)
      Livzon Group Fuzhou Fuxing Pharmaceutical Co.,
                                                                    11,200,000.00          0.00         0.00      0.00        0.00          11,200,000.00
      Ltd. (丽珠集团福州福兴医药有限公司)
      Shenzhen Hiyeah Industry Co., Ltd (深圳市喜悦实
                                                                     6,000,000.00          0.00         0.00      0.00        0.00           6,000,000.00
      业有限公司)
      Joincare Daily-Use & Health Care Co., Ltd. (健康元
                                                                     1,610,047.91          0.00         0.00      0.00        0.00           1,610,047.91
      日用保健品有限公司)
                             Total                                  26,081,354.94          0.00         0.00      0.00        0.00          26,081,354.94



                                                                           230
      Joincare Pharmaceutical Group                                                                        Annual Report 2022


     Goodwill of the Company arose from its business combination involving enterprises not under common
     control in previous years.

      On the balance sheet date, the Company conducts an impairment test on goodwill. When estimating the
      recoverable amount of input costs, it uses a assets group related to goodwill to estimate the present value of
      future cash flows.

     The estimated future cash flow of asset groups is calculated according to the five-year financial budget plan
     made by the management, the cash flows in the years beyond the five-year budget plan remain stable.

     Key assumptions of discounted future cash flow for goodwill impairment test are as follows:

      For the calculation of estimated present value of future cash flow of the asset groups related to goodwill of
      Livzon Group, key assumptions are a gross margin of 63.27%-63.46% and a business revenue growth rate
      of 0-9.08% as well as a cash flow discount rate of 12.21%. The management took into account historical
      conditions and predictions for future market development in making the above assumptions.

     For the calculation of estimated present value of future cash flow of the asset groups related to goodwill of
     Shenzhen Haibin Pharmaceutical Co., Ltd. (深圳市海滨制药有限公司), key assumptions are a gross margin
     of 38.91%-40.11% and a business revenue growth rate of -9.19~2.79% as well as a cash flow discount rate
     of 11.78%. The management took into account historical conditions and predictions for future market
     development in making the above assumptions.

     The calculation of the estimated future present value of the goodwill-related asset portfolio of Livzon Group
     Livzon Pharmaceutical Manufacturing Factory uses a gross profit margin of 82.19%-83.33% and an
     operating income growth rate of 0~7.83%, and a discount cash flow rate of 14.72% as key assumptions.
     Management determines these assumptions based on historical conditions prior to the budget period and
     projections of market developments.

     The calculation of the expected future present value of goodwill-related asset portfolio of Livzon Group
     Fuzhou Fuxing Pharmaceutical Co., Ltd. uses a gross profit margin of 63.43%-64.44% and an operating
     income growth rate of 0~11.80%, and a discount cash flow rate of 15.04% as key assumptions. Management
     determines these assumptions based on historical conditions prior to the budget period and projections of
     market developments.

      As tested, the management of the Company expects that no impairment provision is needed during the
      period.

20. Long-term deferred expenses

                                                                                  Decrease
             Item              2021.12.31       Increase                                      Other          2022.12.31
                                                                        Amortization
                                                                                             decrease
    Renovation costs of
                              26,940,700.02     9,114,501.74               3,437,654.72      212,648.78       32,404,898.26
    offices
    Renovation costs of
                             138,705,258.94    70,216,911.41              31,651,658.96             0.00    177,270,511.39
    plants
    Certification costs of
                                 311,654.79                0.00             120,640.56              0.00        191,014.23
    GMP project
    Others                    34,758,127.18    56,097,158.72              22,844,892.83         9,100.00      68,001,293.07
             Total           200,715,740.93   135,428,571.87              58,054,847.07      221,748.78     277,867,716.95

21. Deferred tax assets and deferred tax liabilities

(1) Deferred tax assets and deferred tax liabilities before offsetting




                                                                  231
     Joincare Pharmaceutical Group                                                                             Annual Report 2022


                                                           2022.12.31                                    2021.12.31
                       Item                    Deductible or                                 Deductible or          Deferred tax
                                                                       Deferred tax
                                              taxable timing                                taxable timing           assets or
                                                                    assets or liabilities
                                                differences                                   differences            liabilities
     Deferred tax assets:
     Provision for impairment of assets        336,502,793.26            51,790,732.85       323,372,877.26         54,704,601.96
     Deductible difference arising from
                                               965,912,234.46           145,014,131.32       945,774,497.50      166,481,490.01
     accrued expenses
     Deductible difference arising from tax
                                               399,128,528.63            61,021,514.54       497,850,865.29         84,167,365.69
     loss
     Deferred income                           329,970,021.95            49,511,503.29       375,321,674.10         60,145,851.14
     Unrealised gains from intra-company
                                               694,726,037.62           104,182,311.29       560,934,298.63         84,185,529.66
     transactions
     Changes in fair value of other equity
                                               146,540,719.40            36,635,179.85       146,653,568.40         36,663,392.10
     instruments
     Deductible difference arising from
                                               107,474,309.53            16,149,104.44        77,872,943.63         11,933,224.52
     share incentive expenses
     Changes in fair value of financial
                                                 7,298,819.37              1,234,418.76        6,918,505.67          1,158,336.82
     assets held for trading
     Other deductible temporary difference     455,485,646.11            68,322,846.92       282,821,670.90         53,103,074.81
                      Total                   3,443,039,110.33          533,861,743.26      3,217,520,901.38     552,542,866.71

     Deferred tax liabilities:
     Changes in fair value of financial
                                                20,269,315.67              3,216,065.39       19,970,547.94          3,215,329.05
     assets held for trading
     Accelerated depreciation of fixed
                                              1,094,571,545.41          167,757,444.03       752,180,706.08      114,114,492.09
     assets
     Changes in fair value of other equity
                                               242,925,303.81            39,399,916.06       359,110,036.65         70,405,084.25
     instruments
     Unrealised gains from intra-company
                                               105,940,000.00            20,791,000.00       105,940,000.00         20,791,000.00
     transactions
                       Total                  1,463,706,164.89          231,164,425.48      1,237,201,290.67     208,525,905.39

(2) Deductible temporary differences and deductible tax losses of unrecognized deferred tax assets

                       Item                                2022.12.31                                    2021.12.31
     Deductible temporary differences                                    239,109,485.46                             175,707,417.84
     Deductible tax loss                                               2,804,958,759.64                         1,365,909,940.62

                       Total                                           3,044,068,245.10                         1,541,617,358.46

(3) Expiry of deductible tax losses in subsequent period

                       Year                             2022.12.31                          2021.12.31                   Note
     2022                                                                     0.00               129,386,282.40
     2023                                                         182,300,762.40                 182,300,761.96
     2024                                                         385,139,111.62                 385,138,859.92
     2025                                                         253,044,280.36                 254,360,863.53
     2026                                                         390,203,263.39                 389,994,598.37
     2027                                                        1,485,158,186.92                            0.00
     Non-expiry                                                   109,113,154.95                  24,728,574.44
                       Total                                     2,804,958,759.64              1,365,909,940.62

22. Other non-current assets

                                                                 232
      Joincare Pharmaceutical Group                                                                Annual Report 2022


                         Item                           2022.12.31                           2021.12.31

      Term deposit and interests                                   812,562,286.58                         52,127,500.00
      VAT carry forward                                               3,338,552.19                        56,384,552.60
      Prepayment for acquisition of project
                                                                   340,456,344.22                     491,703,933.59
      and equipment
      Prepayment for acquisition of technical
                                                                       415,000.00                         63,368,017.61
      know-how
                         Total                                    1,156,772,182.99                    663,584,003.80

23. Short-term loans

(1) Short-term loans by category

                          Item                           2022.12.31                            2021.12.31
      Unsecured loans                                              2,089,585,755.20                      1,666,838,964.15
      Guaranteed loans                                                36,464,859.86                        851,645,870.94
                         Total                                     2,126,050,615.06                      2,518,484,835.09
(2) The Company has no overdue short-term loans.

24. Financial liabilities held for trading

                          Item                           2022.12.31                            2021.12.31
      Financial liabilities held for trading                             755,634.43                            143,302.24
      Including:
        Derivative financial liabilities                                 755,634.43                            143,302.24

                         Total                                           755,634.43                            143,302.24
      Derivative financial liabilities represent foreign currency forward contracts. The loss from unexpired onerous
      contracts measured at fair value on balance sheet date was recognised as financial liabilities held for trading.

25. Notes payable

                        Category                        2022.12.31                           2021.12.31
       Bank acceptance bills                                   1,635,906,989.22                     1,582,386,767.93

      The Company has no overdue notes payable.

26. Accounts payable

                        Item                           2022.12.31                           2021.12.31
      Within one year                                             815,158,453.21                     809,539,858.35
      Over 1 year                                                 128,747,127.70                      62,013,352.16
                        Total                                     943,905,580.91                     871,553,210.51

      No significant accounts payable aging over 1 year at the end of the period.

27. Contract liabilities

                        Item                           2022.12.31                           2021.12.31
      Within one year                                             260,935,024.18                     208,025,612.34



                                                            233
     Joincare Pharmaceutical Group                                                                         Annual Report 2022


     Over 1 year                                                    32,042,706.56                             26,115,089.95
                      Total                                        292,977,730.74                            234,140,702.29

     No significant contract liabilities with ageing for more than 1 year at the end of the period. The amount of
     contract liabilities at beginning of the period recognised as revenue during the period is RMB188,045,099.86.

28. Employee benefits payables

                     Item                2021.12.31            Increase                Decrease               2022.12.31
      Short-term employee benefits       473,806,357.40      2,179,864,994.17        2,082,528,146.47        571,143,205.10
      Post-employment benefits -
                                            341,723.80        146,280,117.93          146,037,217.37             584,624.36
      Defined contribution plans
      Termination benefits                 1,282,742.00            1,880,944.59         1,880,944.59            1,282,742.00
                     Total               475,430,823.20      2,328,026,056.69        2,230,446,308.43        573,010,571.46

(1) Short-term employee benefits

                     Item                   2021.12.31             Increase            Decrease               2022.12.31

     Salaries, bonus and allowances         325,123,978.13     1,788,026,844.16      1,738,082,893.10         375,067,929.19
     Staff welfare                            5,352,134.66          79,667,401.75       79,225,055.24           5,794,481.17
     Social insurances                          569,488.75          59,195,181.10       58,520,239.41           1,244,430.44
     Including: 1. Medical insurance            467,562.91          54,244,259.70       53,558,791.79           1,153,030.82
            2. Work injury insurance             62,711.37           3,046,821.43        3,058,209.96              51,322.84
            3. Maternity insurance               39,214.47           1,904,099.97        1,903,237.66              40,076.78
     Housing fund                             1,493,719.88          60,105,695.76       59,375,841.16           2,223,574.48
     Union funds and staff education            541,564.60           6,475,988.92        6,598,647.56            418,905.96
     Stock Ownership Plan Special
                                            140,725,471.38         186,393,882.48      140,725,470.00         186,393,883.86
     Fund
                     Total                  473,806,357.40     2,179,864,994.17       2,082,528,146.47        571,143,205.10

(2) Defined contribution plans

                      Item                   2021.12.31             Increase            Decrease              2022.12.31

     Post-employment benefits                   341,723.80          146,280,117.93      146,037,217.37           584,624.36
     Including: 1. Basic pension
                                                303,582.07          142,280,070.58      142,038,057.53           545,595.12
     insurance
            2. Unemployment insurance            38,141.73            4,000,047.35          3,999,159.84           39,029.24

                      Total                     341,723.80          146,280,117.93      146,037,217.37           584,624.36

     The Company participates in pension insurance and unemployment insurance plans established by the
     government in accordance with relevant requirements. According to the plans, the Company makes
     contributions to these plans in accordance with relevant requirements of the local government. Save for the
     above contributions, the Company no longer undertakes further payment obligation. The corresponding cost
     is charged to the profit or loss for the current period or the cost of relevant assets when it occurs.

29. Taxes payable

                              Taxation                              2022.12.31                             2021.12.31
      Value-added tax                                                      166,151,353.61                        91,860,518.74



                                                             234
     Joincare Pharmaceutical Group                                                              Annual Report 2022


                           Taxation                                 2022.12.31                  2021.12.31
      Urban maintenance and construction tax                                14,374,197.97             10,047,715.71

      Enterprise income tax                                                124,039,899.44            145,106,168.70
      Property tax                                                           7,992,927.81                 2,178,644.31

      Land use tax                                                           2,847,286.45                 1,716,626.70

      Individual income Tax                                                  7,524,584.67                 9,991,974.56
      Stamp duty                                                             2,904,260.39                  676,792.62

      Education surcharge                                                    9,613,697.69                 6,594,414.24

      Others                                                                 2,254,065.70                 2,445,327.83

                               Total                                       337,702,273.73            270,618,183.41

30. Other payables

                                Item                                2022.12.31               2021.12.31
      Dividends payable                                                   12,252,074.84              6,951,984.46
      Other payables                                                  3,668,082,286.04           3,285,456,005.33
                                Total                                 3,680,334,360.88           3,292,407,989.79

(1) Dividends payable

                                 Item                                2022.12.31              2021.12.31
      Common shares dividend                                                     20,174.46                20,174.46
      Qingyuan Xinbeijiang Enterprise (Group) Co., Ltd.                    1,200,710.00              1,200,710.00
      Other legal persons and individual shareholder of
                                                                           6,682,964.50              3,311,300.00
      subsidiaries
      Internal staff shareholders of subsidiaries                          4,348,225.88              2,419,800.00
                                 Total                                    12,252,074.84              6,951,984.46

(2) Other payables

                       Item                                 2022.12.31                       2021.12.31
     Office expenses                                                      69,513,003.38            66,603,733.56
     Security deposits                                                    89,750,329.22            85,316,947.15
     Business promotion expenses                                      1,722,993,407.82           1,385,121,675.36
     Technology transfer fee                                              10,000,000.00            10,000,000.00
     Accrued expenses                                                 1,714,076,189.32           1,696,272,218.54
     Others                                                               61,749,356.30            42,141,430.72

                       Total                                          3,668,082,286.04           3,285,456,005.33

     The obligations of repurchasing restricted shares held by the directors, the senior management and their
     spouses amounted RMB0.00 at period end.

     Including, details of accrued expenses are as follow:

                                                                                                  Reason of
                   Item                        2022.12.31                2021.12.31          outstanding at year
                                                                                                    end



                                                              235
      Joincare Pharmaceutical Group                                                                                    Annual Report 2022


      Utility bill                                       28,378,759.70                    23,611,733.95                          Unpaid
      Research expenses                                  61,153,064.06                   122,637,625.45                          Unpaid
      Business development and
                                                    1,517,084,251.92                   1,459,695,485.76                          Unpaid
      promotion expenses
      Audit and information
                                                          4,775,560.70                     4,893,299.88                          Unpaid
      disclosure expenses
      Others                                            102,684,552.94                    85,434,073.50                          Unpaid

                     Total                          1,714,076,189.32                   1,696,272,218.54

31. Non-current liabilities due within one year

                                    Item                                    2022.12.31                          2021.12.31

      Lease liabilities due within one year                                           19,415,779.34                        21,295,233.00
      Long-term loans and interest due within one year                                43,661,481.64                        70,280,833.33

                                    Total                                             63,077,260.98                        91,576,066.33

32. Other current liabilities

                             Item                                         2022.12.31                                   2021.12.31

       Output VAT pending for transfer                                                    17,734,822.42                       15,626,224.29
       Payables for goods return                                                          83,440,368.95                                   0.00
       Others                                                                                101,522.98                                   0.00
                         Total                                                           101,276,714.35                       15,626,224.29

33. Long term loans

                                                                                 Range of                                   Range of
                         Item                             2022.12.31                                  2021.12.31
                                                                               interest rate                              interest rate
      Unsecured loans                                    1,475,974,398.32       2.45%-3.20%           897,061,086.11      3.45%-3.70%
      Guaranteed loans                                   1,798,531,126.20       2.70%-3.60%                     0.00
                    Subtotal                             3,274,505,524.52                             897,061,086.11
      Less: Long-term loans due within one
                                                            43,661,481.64                              70,280,833.33
      year
                        Total                            3,230,844,042.88                             826,780,252.78

34. Lease liabilities

                               Item                                      2022.12.31                         2021.12.31
      Lease payments payable                                                   42,898,265.42                        46,367,027.32
      Less: Lease liabilities due within one year                              19,415,779.35                        21,295,233.00
                               Total                                           23,482,486.07                        25,071,794.32

      Interest expenses accrued on lease liabilities within 2022 was RMB3.54 million, which was recorded in
      financial expenses-Interest expense.

35. Deferred income

                                                                                                                             Reason of
               Item                   2021.12.31            Increase             Decrease              2022.12.31
                                                                                                                             formation
      Government grants                433,543,352.40       91,591,736.00        140,597,820.85         384,537,267.55



                                                                         236
     Joincare Pharmaceutical Group                                                                                              Annual Report 2022


     Government grants recorded as deferred income refer to Note 62. Government grants.

36. Other non-current liabilities

                                    Item                                            2022.12.31                                2021.12.31
      The overall relocation and expansion project of
                                                                                              84,000,000.00                              78,000,000.00
      Sichuan Guangda Pharmaceutical Manufacturing

37. Share capital

     In year 2022

                                                                                      Movement in the year (+ or -)
                       Item                    2021.12.31                                                                                   2022.12.31
                                                                 Issue of new Conversion from
                                                                                                           Others         Subtotal
                                                                    shares     capital reserve
       I. Tradable shares subject to
       selling restrictions
       1. Domestic legal person shares                      0                  0                      0               0              0                   0

       2. Domestic natural person shares                    0                  0                      0               0              0                   0

       3. Overseas legal person shares                      0                  0                      0               0              0                   0
       Tradable shares subject to selling
                                                            0                  0                      0               0              0                   0
       restrictions in aggregate
       II. Tradable shares
                                                                                                                                     0                   0
       1. Ordinary shares denominated in
                                               1,907,727,908       72,421,134                         0     -50,959,668     21,461,466      1,929,189,374
       RMB
       2. Domestically listed foreign shares                0                  0                      0               0              0                   0

       Tradable shares in aggregate            1,907,727,908       72,421,134                         0     -50,959,668     21,461,466      1,929,189,374

           III. Total number of shares         1,907,727,908       72,421,134                         0     -50,959,668     21,461,466      1,929,189,374


     The increase in the year: 1. The company issued 6,382,500 GDRs on the Swiss Stock Exchange, representing
     63,825,000 A shares; 2. An increase of 8,596,134 shares due to the exercise of stock options

     The reduction of share capital in this period is cancellation of repurchased shares.

     In year 2021
                                                                                      Movement in the year (+ or -)
                       Item                    2020.12.31                           Conversion                                              2021.12.31
                                                                Issue of new
                                                                                   from capital           Others          Subtotal
                                                                   shares
                                                                                      reserve
       I. Tradable shares subject to
       selling restrictions
       1. Domestic legal person shares                      0                  0                  0                 0                0                   0

       2. Domestic natural person shares                    0                  0                  0                 0                0                   0

       3. Overseas legal person shares                      0                  0                  0                 0                0                   0
       Tradable shares subject to selling
                                                            0                  0                  0                 0                0                   0
       restrictions in aggregate
       II. Tradable shares
       1. Ordinary shares denominated in
                                               1,952,780,764       10,082,440                     0        -55,135,296     -45,052,856      1,907,727,908
       RMB
       2.Domestically listed foreign shares                 0                  0                  0                 0                0                   0

       Tradable shares in aggregate            1,952,780,764       10,082,440                     0        -55,135,296     -45,052,856      1,907,727,908

           III. Total number of shares         1,952,780,764       10,082,440                     0        -55,135,296     -45,052,856      1,907,727,908


     The increase in share capital in this period was due to issue of new shares and the decrease in share capital
     in this period was due to cancellation of repurchased shares.


                                                                          237
     Joincare Pharmaceutical Group                                                               Annual Report 2022


38. Capital reserve

     In year 2022

               Item                  2021.12.31          Increase              Decrease              2022.12.31
      Capital premium                2,152,860,227.84     642,189,404.23        573,367,347.30       2,221,682,284.77
      Other capital reserve            112,497,084.08      30,762,735.61         21,248,888.47         122,010,931.22
               Total                 2,265,357,311.92     672,952,139.84        594,616,235.77       2,343,693,215.99

     The increase in capital premium was due to: 1. The Company's stock options were exercised for 8,596,134
     shares, increasing the capital premium by RMB62,519,504.79, and correspondingly accrued share incentive
     expenses of RMB4,975,185 which were transferred from other capital reserve to capital premium. 2. The
     exercise of share options of the Company’s subsidiary, Livzon Group, increasing the capital premium of
     RMB14,645,670.47 according to shareholding held by the Company, and correspondingly accrued share
     incentive expenses of RMB9,019,288.61 which were transferred from other capital reserve to capital
     premium. 3. After the stock options are exercised, the difference between the tax deductible expenses
     according to tax regulations and the accrued expenses reduces the income tax payable by RMB1,347,279.67,
     which increased the share premium accordingly. 4. The Company issues GDRs on the Swiss Stock Exchange,
     increasing the capital reserve by RMB549,682,475.69.
     The decrease in capital premium was due to: The Company and its subsidiary, Livzon Group, cancelled the
     repurchased shares, the capital premium is reduced by RMB573,367,347.30.

     The increase in other capital reserve was due to: 1. The Company and its subsidiary, Livzon Group, accrued
     share incentive expenses RMB24,733,974.70. 2. The Company’s subsidiary, Livzon Group, made non-
     proportional capital contribution to an investee under equity accounting method that led to change in
     shareholding ratio and other equity, the capital reserve is increased by RMB6,028,760.91.

     The decrease in other capital reserve was due to: 1. The exercise of share incentive by the Company’s
     subsidiary, Livzon Group, caused the changes in the shareholding held by the Company and led to the change
     in other equity, the capital reserve is decreased by RMB7,254,414.86. 2. Transfer of share incentive expenses
     to capital premium of RMB13,994,473.61.

     In year 2021

               Item                  2020.12.31          Increase              Decrease              2021.12.31
      Capital premium                2,531,019,936.35     369,115,622.89        747,275,331.40       2,152,860,227.84
      Other capital reserve              2,268,737.93     114,769,391.67          4,541,045.52         112,497,084.08
               Total                 2,533,288,674.28     483,885,014.56        751,816,376.92       2,265,357,311.92

     Reasons for increase in capital premium: 1) 10,082,440 shares of the Company's stock options were exercised,
     increasing the capital premium by RMB72,493,116.59, and the corresponding accrued share incentive fee of
     RMB1,457,178.93 was transferred from other capital reserves to the capital premium; 2) The Company's
     subsidiary Livzon's stock options are exercised, according to the shareholding ratio of the Company, the
     corresponding increase in the share capital premium of RMB88,109,304.98, and the corresponding accrued
     equity incentive expenses of RMB3,083,866.59 are transferred from other capital reserves to the share capital
     premium; 3) After the exercise of stock options, the difference between the tax deductible expenses and the
     previous accrued expenses resulted in a reduction of income tax payable by RMB13,609,184.27, and the
     share capital premium was increased accordingly; 4) Since the overseas financing of the subsidiary Livzon
     is transferred into the Mainland China and thus the reduction of capital of the subsidiaries are not in the same
     proportion, the difference between the share of net assets of the subsidiaries owned by the Company before
     and after the reduction of capital caused the increase in capital premium by RMB190,362,971.53.

     The decrease in share capital premium of RMB747,275,331.40 for the period was due to the cancellation of
     shares repurchased by the Company and the subsidiary Livzon Group.



                                                           238
     Joincare Pharmaceutical Group                                                                                                        Annual Report 2022


     Reasons for increase in other capital reserves: 1) Share incentive expenses accrued by the Company and the
     subsidiary Livzon Group was RMB11,652,295.42; 2) The subsidiary Livzon Group's equity method
     accounting investment increased capital in different proportions, resulting in changes in the shareholding
     ratio held by the Company and changes in other equity instrument investment, so this caused the capital
     reserve increased by RMB35,846,098.47. 3) The exercise of the stock options of the incentive plan and
     repurchase of shares of the subsidiary Livzon Group lead to changes in the Company's shareholding ratio
     and changes in other equity instrument investment, so this caused the capital reserve decreased by
     RMB55,295,829.27; 4) As the Company disposed of subsidiaries, the capital reserve of RMB11,975,168.51
     transferred to profit or loss for this period.

     Other capital reserves decreased as the equity incentive expenses of RMB4,541,045.52 was transferred to
     the capital premium.

39. Treasury shares

     In year 2022

                                   Item                            2021.12.31                  Increase                Decrease                  2022.12.31
     Repurchase of shares due to Share
     Ownership Scheme and Share Options                          222,644,454.50                            0.00                      0.00       222,644,454.50
     Incentive Scheme
     Repurchase of shares to be cancelled                                      0.00           724,513,822.62           599,981,715.83           124,532,106.79
                                  Total                          222,644,454.50               724,513,822.62           599,981,715.83           347,176,561.29

     The increase in treasury shares in the period is the total amount of funds used by the Company to repurchase
     61,916,903 shares of the Company through centralized bidding transactions.

     The reduction of treasury shares in this period is: Cancellation of repurchased shares.
     In year 2021

                                 Item                            2020.12.31                    Increase                Decrease                   2021.12.31
     Repurchase of shares due to Share
     Ownership Scheme and Share Options                          253,637,154.50                           0.00           30,992,700.00            222,644,454.50
     Incentive Scheme
     Repurchase of shares to be cancelled                                      0.00           699,900,526.87           699,900,526.87                          0.00
                                 Total                           253,637,154.50               699,900,526.87           730,893,226.87             222,644,454.50

     The decrease was due to the transfer to the stock ownership plan account for the current employee stock
     ownership plan and shares incentive.

     The change of repurchase of shares to be cancelled: The increase in treasury shares in this period is the total
     amount of funds used by the Company to repurchase 55,135,296 shares of the Company through centralized
     bidding transactions. The decrease in treasury shares was the cancellation of repurchase shares.

40. Other comprehensive income

     In year 2022
                                                                                                Current year
                                                                                     Less:
                                           2021.12.31                       transferred to                              Amount            Amount      2022.12.31
                   Item                                                      profit or loss                         attributable      attributable
                                              (1)          Amount before                          Less: Income                                        (3) =(1) +(2)
                                                                                in current                             to parent       to minority
                                                                     tax                          tax expenses
                                                                                   year or                             company      interests after
                                                                                  retained                           after tax(2)               tax
                                                                                  earnings
     I. Other comprehensive
     income not reclassified into         102,556,982.18    37,438,265.00   89,722,066.22       -1,303,488.43     -85,577,350.31    34,597,037.52     16,979,631.87
     profit or loss subsequently
     1.Other comprehensive income
     not reclassified to profit or loss     6,658,847.65     4,723,927.54             0.00              0.00       2,116,352.61      2,607,574.93      8,775,200.25
     under equity method



                                                                                 239
     Joincare Pharmaceutical Group                                                                                                                 Annual Report 2022


     2.Changes in fair value of
     other equity instrument               95,898,134.53       32,714,337.46     89,722,066.22      -1,303,488.43       -87,693,702.91       31,989,462.58         8,204,431.61
     investments
     II. Other comprehensive
     income that will be
                                          -97,169,436.20      125,587,048.18               0.00             0.00         84,894,277.87        40,692,770.31      -12,275,158.33
     reclassified into profit or loss
     subsequently
        1.Other comprehensive
     income that will be transferred
                                               37,989.91         527,718.52                0.00             0.00            236,421.59           291,296.93         274,411.50
     to profit or loss under equity
     method
        2.Translation difference of
     foreign currency financial           -97,207,426.12      125,059,329.66               0.00             0.00         84,657,856.28        40,401,473.38      -12,549,569.84
     statements
       Total other comprehensive
                                            5,387,545.97      163,025,313.18     89,722,066.22        -1,303,488.43        -683,072.44       75,289,807.82         4,704,473.53
                   income


     In year 2021
                                                                                                  Current year
                                                                                        Less:
                                           2020.12.31                          transferred to                             Amount                Amount         2021.12.31
                   Item                                                         profit or loss                      attributable to      attributable to
                                              (1)                 Amount                          Less: Income                                                  (3) =(1) +(2)
                                                                                   in current                               parent             minority
                                                                before tax                        tax expenses
                                                                                      year or                       company after         interests after
                                                                                     retained                                tax(2)                   tax
                                                                                     earnings
     I. Other comprehensive
     income not reclassified into         180,616,463.38     43,382,751.21     171,926,789.47     2,196,770.08      -78,059,481.21       -52,681,327.13       102,556,982.18
     profit or loss subsequently
     1.Other comprehensive income
     not reclassified to profit or loss             0.00     14,820,196.44               0.00             0.00        6,658,847.65        8,161,348.794         6,658,847.65
     under equity method
     2.Changes in fair value of other
                                          180,616,463.38     28,562,554.77     171,926,789.47     2,196,770.08      -84,718,328.85       -60,842,675.92        95,898,134.53
     equity instrument investments
     II. Other comprehensive
     income that will be
                                          -64,315,904.10    -46,945,392.92               0.00             0.00      -32,853,532.10       -14,091,860.81       -97,169,436.20
     reclassified into profit or loss
     subsequently
        1.Other comprehensive
     income that will be transferred
                                               51,589.71       -30,268.270               0.00             0.00          -13,599.80          -16,668.468            37,989.91
     to profit or loss under equity
     method
        2.Translation difference of
                                                                         -                                                                            -
     foreign currency financial           -64,367,493.82                                 0.00             0.00      -32,839,932.30                            -97,207,426.12
                                                            46,915,124.650                                                               14,075,192.346
     statements
     Total other comprehensive                                                                                                   -                    -
                                          116,300,559.28     -3,562,641.71     171,926,789.47     2,196,770.08                                                  5,387,545.97
     income                                                                                                         110,913,013.31       66,773,187.941




41. Surplus reserve

     In year 2022

                    Item                         2021.12.31                        Increase                           Decrease                              2022.12.31
       Statutory surplus
                                                   599,506,581.71                    93,945,402.42                                    0.00                   693,451,984.13
       reserve
       Discretionary surplus
                                                    40,210,642.44                                 0.00                                0.00                    40,210,642.44
       reserve
       Reserve funds                                    1,103,954.93                              0.00                                0.00                     1,103,954.93
                   Total                           640,821,179.08                    93,945,402.42                                    0.00                   734,766,581.50

     In year 2021

                    Item                         2020.12.31                        Increase                           Decrease                              2021.12.31
       Statutory surplus
                                                   474,626,867.82                   124,879,713.89                                    0.00                   599,506,581.71
       reserve
       Discretionary surplus
                                                    40,210,642.44                                 0.00                                0.00                    40,210,642.44
       reserve
       Reserve funds                                    1,103,954.93                              0.00                                0.00                     1,103,954.93
                   Total                           515,941,465.19                   124,879,713.89                                    0.00                   640,821,179.08

42. Undistributed profits


                                                                                      240
      Joincare Pharmaceutical Group                                                                        Annual Report 2022


(1) Movement of undistributed profits

                                                                         2022                     2021              Appropriat
                                Item
                                                                                                                     ion ratio
       Retained earnings in previous period before
                                                                      7,223,644,166.22       6,231,451,582.26                 --
       adjustments
       Adjustments to opening balance of retained earnings
                                                                                  0.00                     0.00               --
       (increase +, decrease -)
       Opening balance of retained earnings after adjustments         7,223,644,166.22       6,231,451,582.26
       Add: Net profit attributable to parent company for the
                                                                      1,502,595,840.48       1,328,499,432.05                 --
       current year
        Gains from disposal of other equity instruments
                                                                       101,906,354.19             77,248,253.85               --
       investment
       Less: Appropriation of statutory surplus reserve                 93,945,402.42            124,879,713.89            10%
            Appropriation of discretionary surplus reserve                        0.00                     0.00
            Appropriation for dividends to ordinary shares             277,557,631.65            288,675,388.05
            Dividend to ordinary shares converted to share
                                                                                  0.00                     0.00
       capital
              Closing balance of undistributed profits                8,456,643,326.82       7,223,644,166.22

(2) Profit distributions

                                                                                                                     Unit: RMB

                                  Item                                          2022                         2021
      Dividends:
      2021 year-end dividend (Note 2)                                           277,557,631.65                              0.00
      2020 year-end dividend (Note 3)                                                       --                    288,675,388.05
      Dividends proposed after the balance sheet date:
      2022 year-end dividend (Note 1)                                                     0.00                              0.00
      2021 year-end dividend (Note 2)                                                                             277,557,631.65

      Note 1: On 27 April 2023, the twenty-third meeting of the eighth board of directors of the Company passed
      the 2022 annual profit distribution plan. A cash dividend of RMB1.80 (tax inclusive) for every 10 shares
      would be distributed to all shareholders based on the Company's total share capital, deducted by the
      repurchased shares held in the Company's special securities account, on the equity registration date
      determined by the implementation of the Company's 2022 annual profit distribution plan. The remaining
      undistributed profits are carried forward for distribution in future years.

      Note 2: On 29 March 2022, the ninth meeting of the eighth board of directors of the Company passed the
      2021 annual profit distribution plan. A cash dividend of RMB1.50 (tax inclusive) for every 10 shares would
      be distributed to all shareholders based on the Company's total share capital, deducted by the repurchased
      shares held in the Company's special securities account, on the equity registration date determined by the
      implementation of the Company's 2021 annual profit distribution plan. The remaining undistributed profits
      are carried forward for distribution in future years.

      Note 3: According to the "Profit Distribution Plan for 2020 of the Company" approved by the Company's
      2020 Annual General Meeting of Shareholders on 21 May 2021, the Company distributed cash dividends to
      all shareholders, RMB0.15 per share, based on the 1,924,502,587 shares, which was calculated by the
      1,958,593,217 issued shares registered in China Securities Depository and Clearing Corporation Limited
      (Shenzhen Branch) on 24 June 2020 with deduction of 34,090,630 repurchased shares held in repurchased
      account, the total amount was RMB288,675,388.05.

43. Operating income and operating cost


                                                                241
     Joincare Pharmaceutical Group                                                                                 Annual Report 2022


(1) Operating income and operating cost

                                                     2022                                                   2021
                Item
                                      Revenue                       Cost                     Revenue                     Cost
      Primary operations           17,012,733,738.86           6,160,330,584.19            15,746,624,848.53          5,604,702,296.12
      Other operations                130,019,329.96               91,934,724.21              157,063,418.06           111,591,591.46
                Total              17,142,753,068.82           6,252,265,308.40            15,903,688,266.59          5,716,293,887.58

(2) Primary Disaggregate information of operating income

     ① Segregation by products

                                                       2022                                                    2021
                 Item
                                        Revenue                        Cost                    Revenue                     Cost
      chemical active
      pharmaceutical
      ingredients (APIs) and           5,229,641,907.04            3,409,781,896.55           4,690,255,375.73         3,184,889,165.53
      intermediates (化学原
      料药及中间体)
      Chemical
      pharmaceuticals (化学            9,226,385,569.43            1,813,969,087.68           8,876,919,296.64         1,753,573,833.73
      药物)
      Traditional Chinese
                                       1,296,583,761.24             427,894,665.07            1,109,344,037.45           295,328,306.33
      medicine (中药制剂)
      Biological products (生
                                        408,488,131.90              106,811,638.64              225,756,503.31            15,987,958.28
      物制品)
      Health care products
                                        121,235,545.22               46,223,021.02              115,164,422.30            33,652,500.02
      (保健食品)
      Diagnostic reagents and
      equipment (诊断试剂及             723,535,115.00              352,636,503.06              723,917,736.81           319,168,131.72
      设备)
      Others                                   102,352.31                  263,529.90               254,849.67                 328,336.21
      Subtotal of
                                      17,005,972,382.14            6,157,580,341.92          15,741,612,221.92         5,602,928,231.82
      pharmaceutical industry
      Service industry                     6,761,356.72                2,750,242.27                5,012,626.61            1,774,064.30
                 Total                17,012,733,738.86            6,160,330,584.19          15,746,624,848.53         5,604,702,296.12

     ② Segregation by operating location

                                           2022                                                        2021
        Item
                            Revenue                         Cost                         Revenue                       Cost
     Domestic              14,170,771,017.92           4,326,229,111.25                 13,175,044,906.28          3,837,751,076.40
     Overseas               2,841,962,720.94           1,834,101,472.94                  2,571,579,942.25          1,766,951,219.72
        Total              17,012,733,738.86           6,160,330,584.19                 15,746,624,848.53          5,604,702,296.12

     ③ Segregation by timing of revenue recognition

                                                       2022                                                    2021
                 Item
                                        Revenue                        Cost                    Revenue                        Cost
      Commodities
      (Recognized at a point          17,012,733,738.86            6,160,330,584.19          15,746,624,848.53         5,604,702,296.12
      in time)



                                                                     242
     Joincare Pharmaceutical Group                                                                            Annual Report 2022


     ④ Information of top five customers of business revenue

                                     Total operating revenue from top five       Proportion to primary operating income in
               Period
                                                   customers                                   the period (%)
      2022                                                  1,524,490,064.48                                                  8.96
      2021                                                  1,372,032,796.69                                                  8.71

     ⑤ Segregation by other operations

                                                     2022                                             2021
                Item
                                        Revenue                 Cost                     Revenue                      Cost
      Sale of raw materials              47,190,775.25         31,174,586.16              50,440,716.79              40,772,550.07
      Processing fee                      5,995,904.44          2,546,785.48               6,794,908.37               1,660,944.94
      Rental fees                        10,731,614.42            405,023.12               9,381,937.42                 112,497.34
      Power fee                          11,028,103.39         10,220,631.76              11,855,332.16              11,464,416.78
      Others                             55,072,932.46         47,587,697.69              78,590,523.32              57,581,182.33
                Total                   130,019,329.96         91,934,724.21             157,063,418.06             111,591,591.46

44. Taxes and surcharges

                        Item                                   2022                                       2021
     Urban construction tax                                              86,745,317.20                              78,915,243.23
     Education surcharge                                                 64,105,649.70                              57,919,345.89
     Land use tax                                                        10,656,172.45                               9,853,262.81
     Property tax                                                        24,496,501.64                              22,448,547.60
     Stamp duty and others                                               13,742,716.57                              13,680,250.49

                        Total                                           199,746,357.56                           182,816,650.02

     Note: The bases of calculations for major taxes and surcharges are set out in Note IV. Taxation.

45. Selling expenses

                          Item                                   2022                                        2021
      Marketing and promotional expenses                               4,372,087,623.70                          4,477,764,584.15

      Staff salaries                                                     456,875,210.86                             397,170,070.40
      Entertainment and travel expenses                                   50,363,363.02                              65,297,664.11

      Conference fees                                                     13,696,783.94                              23,554,731.43

      Others                                                              57,779,474.64                              63,025,095.32

                         Total                                         4,950,802,456.16                          5,026,812,145.41

46. Administrative expenses

                          Item                                   2022                                      2021
     Staff salaries                                                       570,458,570.31                             458,139,486.90
     Depreciation and amortisation                                        113,223,517.86                             118,237,699.36
     Loss on suspension of operations                                               0.00                              67,730,993.25



                                                                243
     Joincare Pharmaceutical Group                                                                       Annual Report 2022


     Share incentive expenses                                            56,241,342.12                           27,642,491.39
     Advisory, consultancy and information
     disclosure fees                                                     22,074,505.08                           28,176,640.22

     Quality project expenses                                            29,400,960.89                           46,075,518.11
     Office, entertainment and travelling
     expenses                                                            59,419,007.80                           60,231,705.78
     Repair of utilities, transportation and
     miscellaneous expenses                                              32,266,815.31                           41,571,843.51

     Recruitment and staff training expenses                             10,962,130.33                           10,648,299.29
      Others                                                             98,436,741.81                           80,798,766.52
                        Total                                           992,483,591.51                        939,253,444.33

47. Research and development expenses

                        Item                                   2022                                    2021

      Material costs                                                  290,480,597.96                          289,853,404.42
      Staff salaries                                                  429,267,039.97                          399,459,964.18
      Share incentive expenses                                            835,636.96                             6,884,591.21
      Testing fees                                                    597,331,039.56                          434,694,547.02
      Depreciation and amortisation                                   274,454,884.02                          130,493,088.54
      Acquired Technology                                                        0.00                            7,318,927.47
      Others                                                          149,718,881.47                          128,426,750.49

                        Total                                        1,742,088,079.94                      1,397,131,273.33

48. Financial expenses

                         Item                                  2022                                    2021
     Interest expense                                                  139,016,104.44                             90,278,042.69
     Less: Interest income                                             395,476,309.66                            191,964,051.82
     Exchange gain or loss                                            -104,462,941.41                              2,737,152.59
     Bank charges and others                                             8,475,722.01                              6,054,104.82
                         Total                                        -352,447,424.62                            -92,894,751.72

49. Other income

                                                                                                       Related to assets/
                        Item                          2022                           2021
                                                                                                       Related to income
      Government grants                                 132,272,375.37                59,110,913.13     Related to assets
      Government grants                                 154,570,556.96               186,224,227.56    Related to income
      Handling fees for tax withholding                   3,025,074.11                  2,011,794.27
                        Total                           289,868,006.44               247,346,934.96


     For specific information on government grants, please refer to Note V. 62. Government grants for details.

50. Investment income

                                      Item                                    2022                        2021
     Long-term equity investments income under equity method                 70,577,657.04                       10,281,021.59


                                                               244
      Joincare Pharmaceutical Group                                                                  Annual Report 2022


      Investment income from disposal of long-term equity investments                4,242,404.46           -9,552,139.31
      Investment income from financial assets held for trading during the                                    2,421,216.08
                                                                                       306,526.30
      holding period
      Dividend income from other equity instrument investments                      18,713,637.23           37,114,395.95
      Investment income from disposal of financial assets held for                                          31,616,770.34
                                                                                   -37,867,110.74
      trading
                                        Total                                       55,973,114.29           71,881,264.65

51. Gains from changes in fair value

          Source of gains from changes in fair value                        2022                     2021
      Financial assets held for trading                                            -75,650,657.64           -23,363,035.92
          Including: Debt instruments investment                                        -5,873.00                30,410.89
             Equity instruments investment                                         -73,700,967.89           -17,702,179.18
                  Derivative financial assets                                       -1,943,816.75             -5,691,267.63
      Financial liabilities held for trading                                          -612,332.19              -143,090.17
          Including: Derivative financial liabilities                                 -612,332.19              -143,090.17
                               Total                                               -76,262,989.83           -23,506,126.09

52. Credit impairment loss (“-” for loss)

                             Item                                          2022                      2021
      Bad debts of accounts receivable                                               -2,978,050.82           -9,189,454.14
      Bad debts of other receivables                                                 -1,145,692.55           1,165,341.94
                             Total                                                   -4,123,743.37           -8,024,112.20

53. Assets impairment loss (“-” for loss)

                             Item                                          2022                      2021
      Decline in value of inventories                                              -120,646,933.39          -61,759,256.42
      Impairment loss of fixed assets                                                 -186,548.38            -1,191,722.30
      Impairment loss of intangible assets                                           -3,207,819.01                    0.00
      Impairment loss of construction in progress                                   -11,068,266.54                    0.00
      Impairment loss of development costs                                           -7,518,369.12                    0.00
                             Total                                                 -142,627,936.44          -62,950,978.72

54. Gains from disposal of assets

                                       Item                                         2022             2021
      Gain from disposal of fixed assets (“-” for Loss)                             -705,357.30            6,780,989.95
      Gain from disposal of intangible assets (“-” for Loss)                               0.00           17,263,196.60

                                       Total                                          -705,357.30           24,044,186.55

55. Non-operating income




                                                                     245
     Joincare Pharmaceutical Group                                                                                    Annual Report 2022


                                                                                                                   Amount included in
                         Item                                  2022                          2021                non-recurring gains and
                                                                                                                         losses
     Gains on destruction or retirement of non-
                                                                      520,860.40                    631,652.20                  520,860.40
     current assets
     Income from scraps                                           2,478,956.98                    3,106,514.85               2,478,956.98
     Compensation income                                              542,762.41                    890,504.89                  542,762.41
     Waiver of payables                                           2,671,703.10                      891,816.68               2,671,703.10
     Others                                                       2,015,564.68                    3,121,342.24               2,015,564.68
                         Total                                    8,229,847.57                    8,641,830.86               8,229,847.57

56. Non-operating expenses

                                                                                                                 Amount included in non-
                        Item                                   2022                         2021                  recurring gains and
                                                                                                                         losses
    Donation expenses                                            12,116,987.32                   29,101,247.20              12,116,987.32
    Loss on retirement of non-current assets                     17,045,450.21                    7,057,428.39              17,045,450.21
    Others                                                        2,898,248.53                    3,220,598.10                2,898,248.53
                        Total                                    32,060,686.06                   39,379,273.69              32,060,686.06

57. Income tax expenses

(1) Details of income tax expenses

                                 Item                                              2022                                  2021
     Current income tax                                                                    489,730,614.81                   375,813,164.01
     Deferred income tax                                                                    72,278,243.88                   -36,332,858.72
                                 Total                                                     562,008,858.69                   339,480,305.29

(2) Reconciliation between income tax expenses and accounting profits:

                                         Item                                             2022                           2021
    Profit before tax                                                                 3,456,104,955.17                    2,952,329,343.96
    Income tax expenses calculated at legal/applicable tax rate                            864,026,238.79                   738,082,335.99
    Effect of different tax rates applicable to subsidiaries                                 7,219,165.25                       -157,284.13
    Effect of tax reduction and exemption                                                 -608,357,224.56                  -461,501,254.72
    Effect of non-deductible costs, expenses and losses                                     -1,338,352.12                    11,222,334.85
    Effect of deductible tax losses for which no deferred tax assets
                                                                                            -1,400,449.92                     -1,262,016.75
    were recognised in prior periods
    Effect of deductible tax losses or deductible temporary differences
    for which no deferred tax asset was recognised in the current                          237,204,163.65                    91,064,540.85
    period
    Others                                                                                  64,655,317.60                   -37,968,350.80
                           Income tax expenses                                             562,008,858.69                   339,480,305.29

58. Notes to cash flows statement

(1) Other cash received relating to operating activities

                                     Item                                             2022                               2021



                                                                       246
      Joincare Pharmaceutical Group                                                     Annual Report 2022


       Government grants                                            239,196,300.96         231,492,540.63
       Interest income                                              324,250,238.72         177,822,721.68
       Recovery of employee loans                                        7,299,222.31        8,237,323.25
       Security deposits                                                67,623,532.89       75,737,734.89
       Compensation received                                             1,175,630.74             83,043.02
       Current accounts and others                                      44,100,808.77       51,664,073.17

                                  Total                             683,645,734.39         545,037,436.64

(2) Other cash paid relating to operating activities

                                  Item                            2022                    2021
       Office Expenses                                                  97,503,048.97       98,749,129.18
       Travel expenses                                                  30,372,654.60       69,905,127.66
       Business entertainment expenses                                  69,811,587.72       84,266,002.56
       Freight expenses                                                 50,691,409.60      107,473,996.66
       advertising fee                                                    630,941.00         3,789,481.18
       Conference fees                                                  17,972,567.21       34,011,851.22
       Agency and consulting services fees                              35,039,742.74       43,892,772.99
       R&D expenses                                                 808,023,085.72         756,535,241.25
       Bank charges                                                      7,927,848.89        5,874,566.03
       Petty cash                                                         510,948.05         1,008,235.84
       Business promotion expenses                                4,634,065,689.94       4,832,518,720.60
       Letter of credit and bank acceptance deposit                      1,676,708.15       33,459,360.54
       Other expenses paid and current accounts                     157,458,032.58         214,400,075.57
                                  Total                           5,911,684,265.17       6,285,884,561.28

(3) Other cash received relating to investing activities

                                 Item                            2022                     2021
      Structured Deposits and Term Deposits                                     0.00        100,000,000.00
      Security deposits                                                 7,405,431.82         12,557,736.54
      Compensation for demolition                                       6,000,000.00                   0.00
      Withdrawal of Treasury bonds and margin                             158,470.77          1,013,650.67
      Others                                                                    0.00                2,700.00

                                Total                               13,563,902.59           113,574,087.21

(4) Other cash paid relating to investing activities

                                  Item                            2022                    2021
       Fixed deposits                                             1,084,392,104.38          50,000,000.00
       Security deposits                                                 5,755,128.00            235,000.00
       Foreign exchange forward contract losses                         30,021,080.39        2,831,260.72
       Others                                                                 150.00               3,779.69
                                  Total                           1,120,168,462.77          53,070,040.41


                                                           247
     Joincare Pharmaceutical Group                                                                     Annual Report 2022


(5) Other cash received relating to financing activities

                                 Item                                        2022                         2021
     Equity Transfer fee paid to Guosen Securities Employee                                    0.00         30,992,700.00
     Stock Ownership Plan Account
     Collection and advance payment of individual income                                                     6,859,477.42
                                                                                         347,182.11
     tax
     Discount of acceptance bills                                                    380,719,088.50                    0.00

                                Total                                                381,066,270.61         37,852,177.42

(6) Other cash paid relating to financing activities

                                Item                                         2022                        2021

     Repurchase of shares                                                            780,551,259.85       938,084,088.14
     Capital reduction in minority interests in subsidiary                                     0.00       324,225,000.00
     Rental payments                                                                  32,925,995.59         27,862,261.10
     Collection and advance payment of individual income
                                                                                       1,237,210.80          1,716,145.57
     tax
     Dividend handling fee                                                                     0.00              152,691.48
     GDRs issuance fees                                                               16,003,722.82                    0.00
     Others                                                                              624,000.00                    0.00
                                Total                                                831,342,189.06      1,292,040,186.29




59. Supplement to cash flow statement

(1) Supplement to cash flow statement

                             Supplement information                                  2022                 2021
     1. Reconciliation of net profit to cash flow from operating
     activities:
     Net profit                                                                     2,894,096,096.48      2,612,849,038.67

     Add: Assets impairment loss                                                     142,627,936.44         62,950,978.72

          Credit impairment loss                                                       4,123,743.37          8,024,112.20

     Depreciation of fixed assets                                                    615,224,869.47        540,627,410.92

     Amortisation of right-of-use assets                                              32,367,074.98         26,000,791.57

     Amortization of intangible assets                                               190,110,160.68         53,826,067.53

     Long-term prepaid expenses amortization                                          58,054,847.07         43,989,121.05
     Losses on disposal of fixed assets, intangible assets and other long-                                  -24,044,186.55
                                                                                         705,357.30
     term assets (Gain as in “-”)
     Loss on retirement of fixed assets (Gain as in “-”)                            16,524,589.81          6,425,776.19

     Losses on changes in fair value (Gain as in “-”)                               76,262,989.83         23,506,126.09

     Financial expenses (Gain as in “-”)                                            28,611,954.30        100,946,504.76

     Investment losses (Gain as in “-”)                                             -55,973,114.29        -71,881,264.65

     Decrease in deferred tax assets (Increase as in “-”)                           18,519,526.08         -75,082,337.68

     Increase in deferred tax liabilities (Decrease as in “-”)                      53,643,688.28         28,755,973.72



                                                                   248
     Joincare Pharmaceutical Group                                                                             Annual Report 2022


                            Supplement information                                    2022                          2021

     Decrease in inventories (Increase as in “-”)                                  -604,732,283.55                -306,334,662.14

     Decrease in operating receivables (Increase as in “-”)                       2,380,941,083.00              -1,593,686,129.41

     Increase in operating payables (Decrease as in “-”)                         -1,924,536,232.01               1,036,581,635.58

     Others                                                                            51,132,852.05                    89,634,088.67

     Net cash flows from operating activities                                       3,977,705,139.29               2,563,089,045.24

     2. Significant investment or finance activities not involving cash:
     Conversion of debt into capital                                                              0.00                             0.00

     Convertible bonds mature within one year                                                     0.00                             0.00

     Fixed assets acquired under finance leases                                                   0.00                             0.00

     3. Net increase / (decrease) in cash and cash equivalents:
     Cash and bank balance as at end of year                                       14,178,465,686.40              11,697,518,141.18
     Less: cash and bank balance at beginning of year                              11,697,518,141.18              12,122,781,311.49
     Add: cash equivalents at end of year                                                         0.00                             0.00
     Less: cash equivalents at beginning of year                                                  0.00                             0.00
     Net increase in cash and cash equivalents                                      2,480,947,545.22                -425,263,170.31

(2) Net cash paid for acquisition of subsidiaries during the year
     None.
(3) Net cash received from disposal of subsidiaries during the year
     None.
(4) Details of cash and cash equivalents

                                        Item                                          2022                       2021

     I. Cash                                                                      14,178,465,686.40          11,697,518,141.18
     Including: Cash on hand                                                              231,883.95                225,179.98
     Cash at bank readily available for payment                                   14,164,236,988.28          11,554,754,721.43
     Other monetary fund readily available for payment                                 13,996,814.17            142,538,239.77
     II. Cash equivalents                                                                        0.00                       0.00
     Including: bonds investment mature within 3 months                                          0.00                       0.00
     III. Cash and cash equivalents as at closing balance                         14,178,465,686.40          11,697,518,141.18

     Cash and cash equivalents do not include any cash and cash equivalents that are restricted in use.

60. Ownership or using rights of assets subject to restriction

                                                  Carrying value at
                        Item                                                            Reason of restriction
                                                      year end
                                                                        Security deposits of letters of credit, bank acceptance bills
     Other monetary funds                               1,392,407.76
                                                                                                             and forward settlement
     Notes receivable                                 469,659,266.19                   Bills pool business, pledge notes receivable
                        Total                         471,051,673.95

61. Items in foreign currencies



                                                                  249
      Joincare Pharmaceutical Group                                                                                              Annual Report 2022


                                              Balance in foreign currency                                     Equivalent RMB balance at year
                        Item                                                        Conversion rate
                                                      at year end                                                          end
      Cash and bank balances
      Including: HKD                                           771,333,142.89                   0.89327                                 689,008,756.54
                 Euro                                                 94,684.76                      7.4229                                 702,835.51
                 USD                                           257,758,337.95                        6.9646                         1,795,183,720.46
                 MOP                                              4,921,985.97                       0.8681                               4,272,776.02
                 JPY                                           344,798,878.00                  0.052358                                  18,052,979.65
                 GBP                                                   1,940.10                      8.3941                                  16,285.40
      Accounts receivable
      Including: USD                                             71,530,369.45                       6.9646                             498,180,411.07
                 MOP                                              1,264,788.45                       0.8681                               1,097,962.85
      Other receivables
      Including: USD                                                       21.21                     6.9646                                     147.72
                 HKD                                              3,189,409.63                  0.89327                                   2,849,003.94
                 MOP                                                581,188.00                       0.8681                                 504,529.30
      Other current assets
      Including: USD                                             13,326,786.67                       6.9646                              92,815,738.44
      Short-term loans
      Including: USD                                              1,933,328.53                       6.9646                              13,464,859.86
      Accounts payable
      Including: USD                                                512,475.01                       6.9646                               3,569,183.45
                 Euro                                                  5,665.41                      7.4229                                  42,053.77
                 JPY                                           279,370,752.84                  0.052358                                  14,627,293.88
                 Swiss Franc                                          18,810.00                      7.5432                                 141,887.59
      Other payables
      Including: HKD                                              2,892,127.05                  0.89327                                   2,583,450.33
                 USD                                              4,015,670.14                       6.9646                              27,967,536.26




62. Government grants

(1) Government grants recorded as deferred income and measured at gross amount method subsequently

                                                                                                                                             Item     Related to
                                                               Additions in the Transfer to profit     Other                             presented in   assets/
    Projects with grants        Category Beginning balance                                                            Closing balance
                                                                    year             or loss          movement                              income    Related to
                                                                                                                                          statement    income
Laboratory project of
respiratory system inhalation
preparation engineering          Financial                                                                                                               Related to
                                                3,501,550.00               0.00      1,616,100.00              0.00        1,885,450.00 Other income
                                 allocation                                                                                                                  assets
laboratory project (呼吸系统
吸入制剂工程实验室项目)
Construction of a recycling
production base for
carbapenem products (碳青霉      Financial                                                                                                               Related to
                                                3,625,000.00               0.00              0.00              0.00        3,625,000.00 Other income
                                 allocation                                                                                                                  assets
烯类系列产品循环化生产基
地建设)



                                                                            250
       Joincare Pharmaceutical Group                                                                                          Annual Report 2022


                                                                                                                                         Item     Related to
                                                                Additions in the Transfer to profit    Other                         presented in   assets/
    Projects with grants          Category Beginning balance                                                       Closing balance
                                                                     year             or loss         movement                         income     Related to
                                                                                                                                      statement    income
Construction of an integrated
production line for fully
automatic blister-type dry
powder inhalant micro-filling      Financial                                                                                                        Related to
                                                  927,666.66                0.00        242,000.04          0.00         685,666.62 Other income
and winding (全自动泡罩型          allocation                                                                                                           assets
干粉吸入剂微量灌封与卷绕
一体化生产线建设)
Change in National Science
and Technology Major
Project* Research funding for
lipid injection * Baiyunshan       Financial                                                                                                        Related to
                                                  150,000.00                0.00        150,000.00          0.00                0.00 Other income
Hanfang transfer (国家重大         allocation                                                                                                           assets
专项项目变更*注射脂质研
究经费*白云山汉方转入)
Research on common key
technologies for the large-
scale development of new           Financial                                                                                                        Related to
inhalation preparations (新型                     365,700.00                0.00        365,700.00          0.00                0.00 Other income
                                   allocation                                                                                                           assets
吸入制剂规模化发展共性关
键技术研究)
  2021 Shenzhen Sponge City
Construction Fund
Award*Shenzhen Water               Financial                                                                                                        Related to
Affairs Bureau (2021 年度深                              0.00         895,232.00        134,284.80          0.00         760,947.20 Other income
                                   allocation                                                                                                           assets
圳市海绵城市建设资金奖励
*深圳市水务局)
Large-scale development
subsidy for new inhalation         Financial                                                                                                        Related to
                                                 2,262,600.00               0.00        582,600.00          0.00        1,680,000.00 Other income
preparations (新型吸入制剂         allocation                                                                                                           assets
规模化发展补助)
Project Subsidy of Marine
mollusk kinetic protein (海洋      Financial                                                                                                        Related to
                                                23,840,000.00               0.00     19,562,000.00          0.00        4,278,000.00 Other income
软体动物动能蛋白项目补             allocation                                                                                                           assets
助)
New inhalation drug
formulation creation project       Financial                                                                                                        Related to
                                                67,248,400.00       6,349,500.00     52,689,525.12          0.00       20,908,374.88 Other income
(新型吸入给药制剂创制项            allocation                                                                                                           assets
目)
Zhimu total sapogenin project      Financial                                                                                                        Related to
                                                 8,900,000.00               0.00              0.00          0.00        8,900,000.00 Other income
(知母总皂甙元项目)                 allocation                                                                                                           assets
Glucocorticoid inhalation
                                   Financial                                                                                                        Related to
suspension project (糖皮质混                     3,600,000.00       3,600,000.00              0.00          0.00        7,200,000.00 Other income
                                   allocation                                                                                                           assets
悬液项目)
Government funding for small
molecule peptide project (政       Financial                                                                                                        Related to
                                                  319,999.80                0.00         80,000.04          0.00         239,999.76 Other income
                                   allocation                                                                                                           assets
拨款用于小分子肽项目)
Leulu total sterone project (漏    Financial                                                                                                        Related to
                                                 2,500,000.00               0.00              0.00          0.00        2,500,000.00 Other income
芦总甾酮项目)                      allocation                                                                                                           assets
R&D of active substances
with bone and joint repair and
health care functions(具有         Financial                                                                                                        Related to
                                                  957,649.92                0.00        119,706.24          0.00         837,943.68 Other income
                                   allocation                                                                                                           assets
(骨关节修复与保健) 功能的
活性物质研发)
Key technology research and
development of budesonide
nebulized inhalation solution      Financial                                                                                                        Related to
                                                 2,508,333.33               0.00        350,000.04          0.00        2,158,333.29 Other income
                                   allocation                                                                                                           assets
(布地奈德雾化吸入溶液关
键技术研发)
Return of land holding tax (土     Financial                                                                                                        Related to
                                                 3,567,661.42               0.00        107,029.80          0.00        3,460,631.62 Other income
地使用税返还)                      allocation                                                                                                           assets
Subsidies for the development
of pharmaceutical APIs             Financial                                                                                                        Related to
                                                40,741,354.94               0.00      1,219,192.68          0.00       39,522,162.26 Other income
industry (医药原料药行业发         allocation                                                                                                           assets
展支持资金补助)
Innovation coupon (Jingjin
                                   Financial                                                                                                        Related to
filter press equipment) (创新                     233,332.79                0.00         80,000.04          0.00         153,332.75 Other income
                                   allocation                                                                                                           assets
券(景津压滤设备) )
Xinxiang High-tech Project
                                   Financial                                                                                                        Related to
Fund Support (新乡高新技术                       1,861,111.08               0.00         56,397.36          0.00        1,804,713.72 Other income
                                   allocation                                                                                                           assets
项目资金扶持)


                                                                             251
       Joincare Pharmaceutical Group                                                                                            Annual Report 2022


                                                                                                                                           Item     Related to
                                                                Additions in the Transfer to profit    Other                           presented in   assets/
    Projects with grants          Category Beginning balance                                                         Closing balance
                                                                     year             or loss         movement                           income     Related to
                                                                                                                                        statement    income
Research on Common Co-
construction Technology of
Pharmaceutical Inhalation
Preparations (开发区财政局         Financial                                                                                                          Related to
                                                 2,800,000.00       2,000,000.00              0.00           0.00         4,800,000.00 Other income
                                   allocation                                                                                                             assets
拔款创业领军人才项目: 药
品吸入制剂共性共建技术的
研究)
Research and development of
respiratory system drug and
clinical research technology
service platform project talent    Financial                                                                                                          Related to
                                                 1,500,000.00          50,000.00              0.00           0.00         1,550,000.00 Other income
funding (呼吸系统药物研发          allocation                                                                                                             assets
和临床研究技术服务平台项
目人才经费)
Science and technology help
the economy key special            Financial                                                                                                          Related to
                                                  500,000.00                0.00              0.00           0.00          500,000.00 Other income
projects (科技助力经济重点         allocation                                                                                                             assets
专项)
City Service Development           Financial                                                                                                          Related to
                                                  800,000.00                0.00              0.00           0.00          800,000.00 Other income
Special (市服务发展专项)           allocation                                                                                                             assets
                                   Financial                                                                                                          Related to
Patent funding (专利资助)                         200,000.00                0.00              0.00           0.00          200,000.00 Other income
                                   allocation                                                                                                             assets
2020 Shanghai Professional
Technology Platform
Capacity Enhancement               Financial                                                                                                          Related to
Project (2020 年度上海市专                       1,000,000.00               0.00              0.00           0.00         1,000,000.00 Other income
                                   allocation                                                                                                             assets
业技术平台能力提升项目立
项)
High-growth small and micro
                                   Financial                                                                                                          Related to
innovation enterprises (高成                      400,000.00                0.00              0.00           0.00          400,000.00 Other income
                                   allocation                                                                                                             assets
长小微科创企业)
Technology giant (科技小巨         Financial                                                                                                          Related to
                                                         0.00       1,200,000.00              0.00           0.00         1,200,000.00 Other income
人)                                allocation                                                                                                             assets
First application for corporate
postdoctoral project research      Financial                                                                                                          Related to
funding (首次申请企业博士                                0.00         120,000.00              0.00           0.00          120,000.00 Other income
                                   allocation                                                                                                             assets
后项目研究资助)
Research and development
subsidy for ω-3-Fish Oil
Medium and Long Chain Fat          Financial                                                                                                          Related to
Emulsion Injection (ω-3 鱼油                     350,000.00                0.00        350,000.00           0.00                 0.00 Other income
                                   allocation                                                                                                             assets
中/长链脂肪乳注射液研究
开发补助)
Atmospheric environmental
quality improvement subsidy
funds (Atmospheric                 Financial                                                                                                          Related to
environmental quality                                    0.00         161,504.00          3,588.98           0.00          157,915.02 Other income
                                   allocation                                                                                                             assets
improvement subsidy (大气
环境质量提升补贴)资金)
R&D and industrialization of
innovative Ilaprazole Series       Financial                                                                                                          Related to
                                                16,078,166.25               0.00      4,910,000.04           0.00        11,168,166.21 Other income
(艾普拉唑系列创新药物研            allocation                                                                                                             assets
发及产业化)
Research and development
funds for new drug for Class I
Treatment of Necrosis Factor
in Human Tumour from               Financial                                                                                                          Related to
                                                 8,000,000.00               0.00      5,924,000.00    2,076,000.00                0.00 Other income
Human Source (I 类治疗用人         allocation                                                                                                           income
源化抗人肿瘤坏死因子 α 单
克隆抗体新药研制资金)
Strategic emerging industries
in 2014 (sustained release         Financial                                                                                                          Related to
                                                16,700,000.00               0.00              0.00           0.00        16,700,000.00 Other income
microspheres) (2014 年战略         allocation                                                                                                             assets
性新兴产业 (缓释微球) )
Fund for industrialization of
prolonged-action microsphere       Financial                                                                                                          Related to
                                                12,550,000.00               0.00              0.00           0.00        12,550,000.00 Other income
preparation (长效微球制剂的        allocation                                                                                                             assets
产业化款项)
Construction project for           Financial                                                                                                          Related to
                                                20,719,505.48               0.00      2,405,309.88           0.00        18,314,195.60 Other income
industrialization of               allocation                                                                                                             assets



                                                                             252
       Joincare Pharmaceutical Group                                                                                          Annual Report 2022


                                                                                                                                         Item     Related to
                                                                Additions in the Transfer to profit    Other                         presented in   assets/
    Projects with grants          Category Beginning balance                                                       Closing balance
                                                                     year             or loss         movement                         income     Related to
                                                                                                                                      statement    income
prolonged-action microsphere
preparation (phase I) (长效微
球制剂产业化建设项目 (一
期工程) )
Project subsidy from the
Ministry of Industry and           Financial                                                                                                        Related to
                                                 2,400,000.00               0.00              0.00          0.00        2,400,000.00 Other income
Information Technology (工         allocation                                                                                                           assets
业和信息化部项目补助款)
Project subsidy from the
Ministry of Industry and           Financial                                                                                                        Related to
                                                 1,366,750.00               0.00        231,000.00          0.00        1,135,750.00 Other income
Information Technology (工         allocation                                                                                                           assets
业和信息化部项目补助款)
Construction of Drug
Conformity Evaluation
Research Center Platform (药       Financial                                                                                                        Related to
                                                 1,040,000.14               0.00        159,999.96          0.00         880,000.18 Other income
                                   allocation                                                                                                           assets
物一致性评价研究中心平台
建设)
R&D and Commercialisation
of Mouse Nerve Growth
Factor for Injection (注射用       Financial                                                                                                        Related to
                                                40,045,946.93               0.00     10,560,089.28          0.00       29,485,857.65 Other income
                                   allocation                                                                                                           assets
鼠神经生长因子研发及产业
化)
Demonstration project on the
application of solar
photovoltaic architecture (太      Financial                                                                                                        Related to
                                                 2,455,499.43               0.00      1,102,000.08          0.00        1,353,499.35 Other income
                                   allocation                                                                                                           assets
阳能光电建筑应用示范项
目)
Subsidy for the Tender of
Technology Upgrade Project
for PVC Soft Bag Supported
by Provincial Finance              Financial                                                                                                        Related to
                                                 2,703,484.56               0.00        403,699.30          0.00        2,299,785.26 Other income
Departments (省财政支持技          allocation                                                                                                           assets
改招标项目补助金 PVC 软
袋)
Technical transformation
project of Shenqi Fuzheng
Injection with flexible bag (软    Financial                                                                                                        Related to
                                                15,676,470.62               0.00      3,823,529.40          0.00       11,852,941.22 Other income
                                   allocation                                                                                                           assets
袋(参芪扶正注射液) 技改项
目)
Provision for technology
transformation funds and           Financial                                                                                                        Related to
                                                 5,459,555.72               0.00      1,129,563.36          0.00        4,329,992.36 Other income
subsequent grants (技术改造        allocation                                                                                                           assets
资金拨款及事后补奖)
Provision for technology
transformation funds and           Financial                                                                                                        Related to
                                                 7,359,670.81               0.00      1,783,368.48          0.00        5,576,302.33 Other income
subsequent grants (技术改造        allocation                                                                                                           assets
资金拨款及事后补奖)
Electricity distribution
transformer performance
enhancement for energy-
saving and emission reduction      Financial                                                                                                        Related to
projects (Energy-saving and                       380,000.00                0.00         48,000.00          0.00         332,000.00 Other income
                                   allocation                                                                                                           assets
emission reduction projects
(节能减排项目) ) 配电变压
器能效提升)
R&D and industrialization
team of chemical drug liquid       Financial                                                                                                        Related to
                                                 1,534,833.44         234,000.00         57,999.84          0.00        1,710,833.60 Other income
preparation (化药液体制剂研        allocation                                                                                                           assets
发与产业化团队)
Innovation capacity building
of technology center
(antibody laboratory) (技术中      Financial                                                                                                        Related to
                                                 4,802,478.80               0.00        514,338.20          0.00        4,288,140.60 Other income
                                   allocation                                                                                                           assets
心创新能力建设 (抗体药物
实验室) )
Innovation capacity building
of technology center
(antibody laboratory) (技术中      Financial                                                                                                        Related to
                                                  166,439.46                0.00          6,747.52          0.00         159,691.94 Other income
                                   allocation                                                                                                         income
心创新能力建设 (抗体药物
实验室) )




                                                                             253
       Joincare Pharmaceutical Group                                                                                          Annual Report 2022


                                                                                                                                         Item     Related to
                                                                Additions in the Transfer to profit    Other                         presented in   assets/
    Projects with grants          Category Beginning balance                                                       Closing balance
                                                                     year             or loss         movement                         income     Related to
                                                                                                                                      statement    income
Achievement transfer of
blood screening (BCI) nucleic
acid detection testing (血液筛     Financial                                                                                                        Related to
                                                 3,961,282.44               0.00        631,622.73          0.00        3,329,659.71 Other income
                                   allocation                                                                                                           assets
查 (BCI) 核酸检测试剂成
果转化)
Technological upgrading and
transformation projects of
workshop for acarbose (APIs
for α-glucosidase inhibitor)      Financial                                                                                                        Related to
                                                  464,285.80                0.00        107,142.84          0.00         357,142.96 Other income
(α-葡萄糖苷酶抑制剂类原料         allocation                                                                                                           assets
药阿卡波糖生产车间工艺升
级技术改造项目)
R&D and industrialization of
                                   Financial                                                                                                        Related to
Statins (降血脂他汀类药物                          30,000.48                0.00         30,000.48          0.00                0.00 Other income
                                   allocation                                                                                                           assets
的研发与产业化)
Scientific technology award
and subsidy for technological      Financial                                                                                                        Related to
                                                   28,566.20                0.00         28,566.20          0.00                0.00 Other income
innovative project (科学技术       allocation                                                                                                           assets
奖及科技创新项目资助)
Scientific technology award
and subsidy for technological      Financial                                                                                                        Related to
                                                 2,200,000.00               0.00              0.00          0.00        2,200,000.00 Other income
innovative project (科学技术       allocation                                                                                                         income
奖及科技创新项目资助)
Zhuhai industrial enterprise
“cloud and platform” service
coupons supporting funds (珠       Financial                                                                                                        Related to
                                                   89,431.86                0.00         25,540.86          0.00           63,891.00 Other income
                                   allocation                                                                                                         income
海市工业企业 “云上平台”
服务券支持资金)
Commissioner workstation           Financial                                                                                                        Related to
                                                   85,000.00                0.00         60,000.00          0.00           25,000.00 Other income
(特派员工作站)                     allocation                                                                                                           assets
Industrial revitalisation
                                   Financial                                                                                                        Related to
supporting funds (产业振兴                       2,445,500.01               0.00      1,158,000.00          0.00        1,287,500.01 Other income
                                   allocation                                                                                                           assets
扶持资金)
Phase IV clinical study of
innovative drug Ilaprazole (创     Financial                                                                                                        Related to
                                                 8,210,800.00               0.00      8,210,800.00          0.00                0.00 Other income
新药物艾普拉唑 IV 期临床           allocation                                                                                                           assets
研究)
Government grant for
                                   Financial                                                                                                        Related to
industrial transformation (工                     308,333.75                0.00        199,999.92          0.00         108,333.83 Other income
                                   allocation                                                                                                           assets
业转型政府扶持资金)
New industrialization
                                   Financial                                                                                                        Related to
development grant (新型工业                      3,584,066.38       1,801,800.00        350,000.04          0.00        5,035,866.34 Other income
                                   allocation                                                                                                           assets
化发展奖金)
Policy fund for leading
industrial enterprises loan        Financial                                                                                                        Related to
                                                  366,666.57                0.00        200,000.04          0.00         166,666.53 Other income
Interests (工业龙头企业贷款        allocation                                                                                                           assets
贴息政策资金)
Supporting funds for five
advantageous industrial
clusters and one high-tech         Financial                                                                                                        Related to
                                                  300,000.20                0.00         99,999.96          0.00         200,000.24 Other income
                                   allocation                                                                                                           assets
industry (五优一新扶持资
金)
Capital project for innovation
and entrepreneurship team          Financial                                                                                                        Related to
                                                12,500,000.00               0.00        750,000.00          0.00       11,750,000.00 Other income
funding program (创新创业          allocation                                                                                                           assets
团队资助计划资金项目)
2020 Zhuhai City Innovation
and Entrepreneurship Team
(Nanocrystalline) (2020 年度       Financial                                                                                                        Related to
                                                 1,500,000.00       3,500,000.00              0.00          0.00        5,000,000.00 Other income
                                   allocation                                                                                                           assets
珠海市创新创业团队 (纳米
晶) )
Fund for R&D and
industrialization of innovative
Ilaprazole series (艾普拉唑系      Financial                                                                                                        Related to
                                                 5,600,000.00               0.00      5,600,000.00          0.00                0.00 Other income
                                   allocation                                                                                                           assets
列创新药物研发及产业化) )
项目资金)
Key projects of industrial core
and key technologies of            Financial                                                                                                        Related to
                                                 3,000,000.00               0.00              0.00          0.00        3,000,000.00 Other income
                                   allocation                                                                                                           assets
Zhuhai (Ryanodex) (珠海市



                                                                             254
       Joincare Pharmaceutical Group                                                                                           Annual Report 2022


                                                                                                                                          Item     Related to
                                                                 Additions in the Transfer to profit    Other                         presented in   assets/
    Projects with grants           Category Beginning balance                                                       Closing balance
                                                                      year             or loss         movement                         income     Related to
                                                                                                                                       statement    income
产业核心和关键技术攻关方
向项目 (丹曲林钠) )
Data-driven industrial chain
collaboration platform
demonstration project (数据         Financial                                                                                                        Related to
                                                  3,650,000.00               0.00        730,000.00          0.00        2,920,000.00 Other income
                                    allocation                                                                                                           assets
驱动的产业链协同平台示范
项目)
Fund for key projects of
industrial core and key
technologies of Zhuhai (2nd         Financial                                                                                                        Related to
batch) (珠海市产业核心和关                        2,000,000.00               0.00              0.00          0.00        2,000,000.00 Other income
                                    allocation                                                                                                           assets
键技术攻关方向项目资金
(第二批) )
Innovative drug of Ilaprazole
                                    Financial                                                                                                        Related to
sodium for injection (创新药                      2,400,000.00               0.00        120,000.00          0.00        2,280,000.00 Other income
                                    allocation                                                                                                           assets
注射用艾普拉唑钠针剂)
Technological transformation
projects of new Cefuroxime          Financial                                                                                                        Related to
                                                  1,533,100.00               0.00              0.00          0.00        1,533,100.00 Other income
(新型头孢粉针剂技术改造             allocation                                                                                                           assets
项目)
Advanced Pharmaceutical
Manufacturing Internet              Financial                                                                                                        Related to
                                                   675,000.00                0.00         90,000.00          0.00         585,000.00 Other income
Benchmarking Project (先进          allocation                                                                                                           assets
药品制造互联网标杆项目)
Cleaner Production Audit            Financial                                                                                                        Related to
                                                   180,000.08                0.00          9,999.96          0.00         170,000.12 Other income
Project (清洁生产审核项目)          allocation                                                                                                           assets
                                    Financial                                                                                                        Related to
Green factory (绿色工厂)                          1,131,666.71               0.00        129,999.96          0.00        1,001,666.75 Other income
                                    allocation                                                                                                           assets
HCG PROJECT
CONSTRUCTION (HCG 项                Financial                                                                                                        Related to
                                                  3,387,835.84               0.00        395,649.96          0.00        2,992,185.88 Other income
                                    allocation                                                                                                           assets
目建设)
Sewage treatment system
upgrade project (污水处理系         Financial                                                                                                        Related to
                                                    64,239.92                0.00          8,030.04          0.00           56,209.88 Other income
                                    allocation                                                                                                           assets
统升级改造项目)
R&D and industrialization of
Recombinant Human
Chorionic Gonadotropin for          Financial                                                                                                        Related to
                                                  1,137,500.00               0.00        150,000.00          0.00         987,500.00 Other income
Injection (注射用重组人绒促         allocation                                                                                                           assets
性素研发及产业化)
Development and
Industrialization of
Cyclosporin Self-emulsifying
Soft Capsules with High             Financial                                                                                                        Related to
                                                         0.00          800,000.00         14,000.00          0.00         786,000.00 Other income
Technology Barriers (高技术         allocation                                                                                                           assets
屛障的环孢素自乳化软胶囊
制剂的开发及产业化研究)
Guangdong Provincial Key
Laboratory of Characteristic
Drug R&D Enterprises (广东          Financial                                                                                                        Related to
                                                         0.00        1,000,000.00         58,333.31          0.00         941,666.69 Other income
                                    allocation                                                                                                           assets
省特色药物研发企业重点实
验室)
Subsidies for online
monitoring equipment and
installations of coalfired          Financial                                                                                                        Related to
                                                    82,500.00                0.00         22,500.00          0.00           60,000.00 Other income
                                    allocation                                                                                                           assets
boilers (燃煤锅炉在线监控
设备装置补助) ) 资金)
Funds for joint R&D and
industrialization of integrated
platform for molecular              Financial                                                                                                        Related to
diagnostics (集成一体化分子                        181,632.12                0.00        127,715.81          0.00           53,916.31 Other income
                                    allocation                                                                                                           assets
诊断平台的合作研发及产业
化) ) 资金)
Project supporting fund for
the first batch of special funds
for scientific and
technological innovation in         Financial                                                                                                        Related to
                                                   600,000.00                0.00              0.00          0.00         600,000.00 Other income
2019 (2019 年度第一批科技           allocation                                                                                                           assets
创新专项资金立项配套资
助)




                                                                              255
       Joincare Pharmaceutical Group                                                                                           Annual Report 2022


                                                                                                                                          Item     Related to
                                                                Additions in the Transfer to profit    Other                          presented in   assets/
    Projects with grants          Category Beginning balance                                                        Closing balance
                                                                     year             or loss         movement                          income     Related to
                                                                                                                                       statement    income
Provincial industrial
innovation (provincial
enterprise technology center)      Financial                                                                                                         Related to
project in 2019 (2019 年度省                     1,046,533.33               0.00        967,303.60           0.00           79,229.73 Other income
                                   allocation                                                                                                            assets
产业创新 (省级企业技术中
心) 项目)
China Postdoctoral Science
Foundation subsidy funds (中       Financial                                                                                                         Related to
                                                   80,000.00                0.00          6,283.19      73,716.81                0.00 Other income
国博士后科学基金会资助经           allocation                                                                                                          income
费)
Pre-appropriation of special
grants for industrialization of
diagnostic reagents for            Financial                                                                                                         Related to
COVID-19 (新型冠状病毒检                         4,116,415.65               0.00         26,694.08           0.00        4,089,721.57 Other income
                                   allocation                                                                                                            assets
测试剂产业化项目补助金预
拨)
Xiangzhou District equipment
purchase subsidy supporting
funds (Special funds for
epidemic prevention and            Financial                                                                                                         Related to
                                                   11,467.25                0.00          2,317.04           0.00            9,150.21 Other income
control) (香洲区采购设备补         allocation                                                                                                            assets
贴扶持资金 (疫情防控专项
资金)
Zhuhai innovation and
enterprising team and high-
level talent enterprising          Financial                                                                                                         Related to
project Phase I funds (珠海市                   12,000,000.00               0.00              0.00           0.00       12,000,000.00 Other income
                                   allocation                                                                                                            assets
创新创业团队和高层次人才
创业项目首期资金)
Overall relocation and
deployment expansion project       Financial                                                                                                         Related to
                                                20,000,000.00      30,000,000.00              0.00           0.00       50,000,000.00 Other income
                                   allocation                                                                                                            assets
(整体搬迁调迁扩建项目)
Environmental protection
bureau RTO project special         Financial                                                                                                         Related to
                                                  179,999.96                0.00         20,000.04           0.00         159,999.92 Other income
funds (环保局 RTO 项目资           allocation                                                                                                            assets
金)
Structure-efficiency
optimization of marine
microorganisms and                 Financial                                                                                                         Related to
evaluation of antitumor                           312,366.27                0.00        213,157.10           0.00           99,209.17 Other income
                                   allocation                                                                                                          income
activity (海洋微生物构效优
化与抗肿瘤活性评价)
R&D and demonstration of
key technologies for the
development and utilization
of swim bladder (golden
oyster) marine traditional         Financial                                                                                                         Related to
                                                         0.00         750,000.00              0.00           0.00         750,000.00 Other income
Chinese medicine resources         allocation                                                                                                          income
(鱼鳔(黄金鮸) 海洋中药资
源开发与利用关键技术研发
与示范)
2022 Special funds for the
reconstruction of the
industrial base and the high-
quality development of the
manufacturing industry from        Financial                                                                                                         Related to
                                                         0.00      32,740,000.00      4,774,583.31           0.00       27,965,416.69 Other income
the central finance (2022 年       allocation                                                                                                            assets
中央财政产业基础再造和制
造业高质量发展专项资金)
示范)
National Science and
Technology Major Special
Project Subsidy Fund               Financial                                                                                                         Related to
                                                         0.00       4,744,900.00      2,362,093.09           0.00        2,382,806.91 Other income
LZM009 (国家科技重大专             allocation                                                                                                            assets
项项目后补助资金
LZM009)
Xiangzhou District actively
responds to the impact of the
                                   Financial                                                                                                         Related to
epidemic and maintains                                   0.00       1,644,800.00              0.00           0.00        1,644,800.00 Other income
                                   allocation                                                                                                          income
stability, innovation drives
technology industry project



                                                                             256
     Joincare Pharmaceutical Group                                                                                                       Annual Report 2022


                                                                                                                                                      Item     Related to
                                                                  Additions in the Transfer to profit         Other                               presented in   assets/
   Projects with grants        Category Beginning balance                                                                   Closing balance
                                                                       year             or loss              movement                               income     Related to
                                                                                                                                                   statement    income
(香洲区积极应对和疫情影
响保稳创新驱动科技工业分
项)
          Total                                433,543,352.40        91,591,736.00       138,448,104.04      2,149,716.81      384,537,267.55


(2) Government grants recognized in income for the year by gross method

                                                                                                              Amount
                                                                                      Amount recognised                            Presented in       Related to
                                                                                                            recognised in
                       Projects with grants                          Category         in profit or loss in                            income        assets/ Related
                                                                                                           profit or loss in
                                                                                          prior year                                statement         to income
                                                                                                              the year
                                                                         Financial                                                                       Related to
     Social security subsidy (社保补助)                                                         72,684.89          226,308.66       Other income
                                                                         allocation                                                                        income
                                                                         Financial                                                                       Related to
     Patent grant (专利补助)                                                                   300,000.00            2,500.00       Other income
                                                                         allocation                                                                        income
                                                                         Financial                                                                       Related to
     Job stabilization subsidy (稳岗补贴)                                                      122,853.35        1,075,941.53       Other income
                                                                         allocation                                                                        income
                                                                         Financial                                                                       Related to
     Electricity subsidy (用电补助)                                                          1,245,193.22          570,533.30       Other income
                                                                         allocation                                                                        income
                                                                         Financial                                                                       Related to
     Maternity benefits (生育津贴)                                                             298,510.00          404,108.83       Other income
                                                                         allocation                                                                        income
                                                                         Financial                                                                       Related to
     Export credit insurance subsidy (出口信保补贴)                                            364,900.00        1,126,400.00       Other income
                                                                         allocation                                                                        income
     New inhalation drug formulation creation project (新型              Financial
                                                                                                      0.00      53,637,825.12       Other income Related to assets
     吸入给药制剂创制项目)                                               allocation
     Budesonide project acceptance transferred to other                  Financial
                                                                                             1,991,666.67          350,000.04       Other income Related to assets
     income (布地奈德项目验收转其他收益)                                 allocation
                                                                         Financial                                                                       Related to
     Enterprise R&D investment plan (企业研发投入计划)                                       2,000,000.00                   0.00    Other income
                                                                         allocation                                                                        income
                                                                         Financial                                                                       Related to
     Job training subsidy (适岗培训补贴 )                                                      236,835.00                   0.00    Other income
                                                                         allocation                                                                        income
     Construction of an integrated production line for fully
     automatic blister-type dry powder inhalant micro-filling            Financial
                                                                                             1,492,333.34                   0.00    Other income Related to assets
     and winding (全自动泡罩型干粉吸入剂微量灌封与卷                     allocation
     绕一体化生产线建设)
     Study on the technology of antifungal drug caspofungin              Financial
                                                                                             1,500,000.00                   0.00    Other income Related to assets
     (抗真菌药卡泊芬净工艺研究)                                          allocation
     Laboratory project of respiratory system inhalation
     preparation engineering laboratory project (呼吸系统吸              Financial
                                                                                             1,346,750.00                   0.00    Other income Related to assets
                                                                         allocation
     入制剂工程实验室项目)
     Laboratory project of respiratory system inhalation
     preparation engineering laboratory project (呼吸系统吸              Financial
                                                                                                      0.00       1,616,100.00       Other income Related to assets
                                                                         allocation
     入制剂工程实验室项目)
     The 9th batch of job training subsidies for enterprises in
                                                                         Financial                                                                       Related to
     Yantian District in 2020 (2020 年盐田区企业适岗培训                                     2,880,000.00                   0.00    Other income
                                                                         allocation                                                                        income
     补贴第 9 批次)
     The first batch of funding support for the development of
                                                                         Financial                                                                       Related to
     science and technology industries in 2021 (2021 年第一                                  3,000,000.00                   0.00    Other income
                                                                         allocation                                                                        income
     批科技类产业发展资金扶持资助)
     2015 Pilot Project of United Development of Emerging
     Strategic Industrial Regions in Guangdong Province                  Financial
                                                                                             9,500,002.00                   0.00    Other income Related to assets
     (2015 年广东省战略性新兴产业区域集聚发展试点项                      allocation
     目)
     Funds allocated by the Ministry of Finance (财政局拨付              Financial
                                                                                             1,219,192.66        1,219,192.68       Other income Related to assets
     补助资金)                                                           allocation
     Special funds for corporate R&D financial subsidies in              Financial                                                                       Related to
                                                                                               720,000.00                   0.00    Other income
     2020 (2020 年企业研发财政补助专项资金)                              allocation                                                                        income
     The third batch of biopharmaceutical industry leader (第            Financial                                                                       Related to
                                                                                               500,000.00                   0.00    Other income
     三批次生物医药产业领航)                                             allocation                                                                        income
     Compensation for temporary land occupation at
                                                                         Financial                                                                       Related to
     Songping Station of Metro Line 13 (地铁 13 号线松坪                                              0.00         361,614.00       Other income
                                                                         allocation                                                                        income
     站临时占地补偿款)
                                                                         Financial                                                                       Related to
     Quarterly property tax relief (减免一个季度房产税)                                               0.00         583,508.46       Other income
                                                                         allocation                                                                        income
     Amortization of Deferred Earnings*Marine Projects (摊               Financial
                                                                                                      0.00      19,562,000.00       Other income Related to assets
     销递延收益*海洋项目)                                                allocation
     Quality brand double promotion support plan (质量品牌               Financial                                                                       Related to
                                                                                               400,000.00                   0.00    Other income
     双提升扶持计划)                                                     allocation                                                                        income



                                                                                257
Joincare Pharmaceutical Group                                                                                 Annual Report 2022


The first batch of funding for the 2020 Enterprise
                                                              Financial                                                      Related to
Research and Development Funding Program (2020 年企                         871,000.00            0.00   Other income
                                                              allocation                                                       income
业研究开发资助计划第一批资助)
Deferred income 摊销*国家重大专项项目注射脂质研               Financial
                                                                                   0.00    500,000.00    Other income Related to assets
究经费(已验收)                                                allocation
Industrial value-added growth rate projects (工业增加值       Financial                                                      Related to
                                                                                   0.00   1,145,100.00   Other income
增速达标项目)                                                 allocation                                                       income
2021 Annual Industrial Added Value Growth Standard            Financial                                                      Related to
                                                                                   0.00    946,624.88    Other income
Award (2021 年度工业增加值增速达标奖励)                       allocation                                                       income
2022 Industrial Enterprise Expansion and Efficiency
Support Program Funding (2022 年工业企业扩产增效              Financial                                                      Related to
                                                                                   0.00   1,650,000.00   Other income
                                                              allocation                                                       income
扶持计划资助)
2022 High-tech Enterprise Cultivation Funding First
Batch of Grants Shenzhen Science and Technology               Financial                                                      Related to
                                                                                   0.00    500,000.00    Other income
Innovation No. 202225 (2022 年高新技术企业培育资              allocation                                                       income
助第一批拨款深科技创新 202225 号)
2022 Industrial "Carbon Peak" Pilot Demonstration
                                                              Financial                                                      Related to
Project Funding Fund (2022 年工业“碳达峰”工作试点                                0.00    500,000.00    Other income
                                                              allocation                                                       income
示范项目资助款)
Freeze-dried raw material production line project funding     Financial                                                      Related to
                                                                                   0.00   2,045,300.00   Other income
(冻干原料生产线项目资助经费)                                  allocation                                                       income
Funds for Encouraging Industrial Enterprises to Expand
                                                              Financial                                                      Related to
Production and Increase Efficiency (鼓励工业企业扩产                               0.00    620,000.00    Other income
                                                              allocation                                                       income
增效项目经费)
Preclinical study of targeted anti-tumor innovative drug      Financial                                                      Related to
                                                                            500,000.00            0.00   Other income
JK00265 (靶向抗肿瘤创新药物 JK00265 临床前研究)               allocation                                                       income
Science and Technology Development Fund for
                                                              Financial                                                      Related to
Enterprise R&D Institutions in Pudong New District (浦                      800,000.00            0.00   Other income
                                                              allocation                                                       income
东新区科技发展基金企业研发机构专项)
Special subsidy for research and development expenses         Financial                                                      Related to
                                                                            550,000.00     100,000.00    Other income
of gazelle enterprises (瞪羚企业研发费专项补助)               allocation                                                       income
2022 The central government guides local science and
technology development funds (2022 年中央引导地方             Financial                                                      Related to
                                                                                   0.00    400,000.00    Other income
                                                              allocation                                                       income
科技发展资金 40 万)
Funds to support business development (扶持企业发展           Financial                                                      Related to
                                                                                   0.00   3,543,000.00   Other income
资金)                                                         allocation                                                       income
Grant Funding for Science and Technology Projects (科         Financial                                                      Related to
                                                                                   0.00   1,500,000.00   Other income
技项目补助资金)                                               allocation                                                       income
                                                              Financial                                                      Related to
Government grants                                                                  0.00   1,400,000.00   Other income
                                                              allocation                                                       income
2022 High-tech Cultivation Fund (22 年高新培育资助            Financial                                                      Related to
                                                                                   0.00    500,000.00    Other income
款)                                                           allocation                                                       income
2022 Shenzhen High-tech Zone Special Fund Municipal           Financial                                                      Related to
                                                                                   0.00    750,000.00    Other income
Funding (2022 年度深圳高新区专项资金市级资助款)               allocation                                                       income
In the first half of 2022, subsidies for industrial
assistance projects to help enterprises bail out (2022 年上   Financial                                                      Related to
                                                                                   0.00    383,300.00    Other income
                                                              allocation                                                       income
半年工业助企纾困项目补助)
High-tech Zone Finance Bureau’s 2021 special funds for
enterprise R&D financial subsidies (高新区财政局 2021         Financial                                                      Related to
                                                                                   0.00    320,000.00    Other income
                                                              allocation                                                       income
年企业研发财政补助专项资金) )
High-tech Zone Finance Bureau 2022 Central Air
                                                              Financial                                                      Related to
Pollution Prevention and Control Fund (高新区财政局                                0.00    750,000.00    Other income
                                                              allocation                                                       income
2022 年中央大气污染防治资金)
The second batch of funding plans for technological
                                                              Financial                                                      Related to
transformation investment projects in 2021 (2021 年技术                    1,710,000.00           0.00   Other income
                                                              allocation                                                       income
改造投资项目第二批资助计划)
2022 Shenzhen High-tech Zone Development Special
Plan Science and Technology Enterprise Cultivation            Financial                                                      Related to
                                                                                   0.00    500,000.00    Other income
Project Subsidy (2022 年度深圳高新区发展专项计划              allocation                                                       income
科技企业培育项目补助-深圳市坪山区科技创新局)
                                                              Financial                                                      Related to
One-time job training subsidy (一次性留工培训补助)                                 0.00    311,875.00    Other income
                                                              allocation                                                       income
Government Subsidy of Special Fund for Scientific and
Technological Innovation-Shenzhen Pingshan District           Financial                                                      Related to
                                                                           1,085,794.00           0.00   Other income
Science and Technology Innovation Bureau (科技创新            allocation                                                       income
专项资金政府补助-深圳市坪山区科技创新局)
                                                              Financial                                                      Related to
Export credit insurance subsidy (出口信保补贴)                             1,991,489.70   2,087,098.80   Other income
                                                              allocation                                                       income
                                                              Financial                                                      Related to
R&D subsidy (研究开发费补助))                                              6,267,222.00   1,200,440.00   Other income
                                                              allocation                                                       income
Research and development funds for new drug for Class I       Financial                                                      Related to
                                                                                   0.00   5,924,000.00   Other income
Treatment of Necrosis Factor in Human Tumour from             allocation                                                       income



                                                                    258
Joincare Pharmaceutical Group                                                                                  Annual Report 2022


Human Source (I 类治疗用人源化抗人肿瘤坏死因子 α
单克隆抗体新药的研制资金)
Government Subsidy for Long-acting Microspheres
                                                            Financial
Major New Drug Creation (长效微球重大新药创制政                            4,784,320.37    3,155,309.88   Other income Related to assets
                                                            allocation
府补助)
R&D and industrialization of innovative Ilaprazole Series   Financial
                                                                           4,910,000.04   18,720,800.04   Other income Related to assets
(艾普拉唑系列创新药物研发及产业化)                          allocation
R&D and industrialization of innovative Ilaprazole Series   Financial                                                         Related to
                                                                            560,000.00             0.00   Other income
(艾普拉唑系列创新药物研发及产业化)                          allocation                                                          income
                                                            Financial
HCG PROJECT CONSTRUCTION (HCG 项目建设)                                     395,649.97      395,649.96    Other income Related to assets
                                                            allocation
Fiscal Subsidy and Operating Subsidy (财政补贴及经营        Financial                                                         Related to
                                                                         119,047,484.00   59,063,950.86   Other income
运营补贴)                                                   allocation                                                          income
R&D and Commercialisation of Mouse Nerve Growth
Factor for Injection (注射用鼠神经生长因子研发及产          Financial
                                                                          10,560,089.27   10,560,089.28   Other income Related to assets
                                                            allocation
业化)
Provincial Science and Technology Innovation Strategy       Financial
                                                                            473,166.56       57,999.84    Other income Related to assets
Special Fund (省科技创新战略专项资金)                       allocation
Import discount and supporting funds (进口贴息及配套        Financial                                                         Related to
                                                                                   0.00     500,000.00    Other income
资金)                                                       allocation                                                          income
Promoting Imports of Foreign Trade Development              Financial                                                         Related to
                                                                              50,352.00    1,809,479.00   Other income
Special Fund (外贸经济发展专项资金)                         allocation                                                          income
Subsidy for the Tender of Technology Upgrade Project
for PVC Soft Bag Supported by Provincial Finance            Financial
                                                                            408,365.76      403,699.30    Other income Related to assets
Departments (省财政支持技改招标项目补助金 PVC               allocation
软袋)
Technical transformation project of Shenqi Fuzheng
                                                            Financial
Injection with flexible bag (软袋(参芪扶正注射液) 技                       3,823,529.40    3,823,529.40   Other income Related to assets
                                                            allocation
改项目)
Demonstration project on the application of solar
                                                            Financial
photovoltaic architecture (太阳能光电建筑应用示范项                        1,102,000.08    1,102,000.08   Other income Related to assets
                                                            allocation
目)
                                                            Financial                                                         Related to
Electricity Incentive Funds (用电奖励资金)                                  364,257.43       20,000.00    Other income
                                                            allocation                                                          income
Subsidies for high and new technology enterprises and
high and new technology products (高新技术企业及高          Financial                                                         Related to
                                                                           1,071,346.00     250,000.00    Other income
                                                            allocation                                                          income
新技术产品项目补贴)
Grants to high-growth technology companies from
Dazhangjiang project A04 (大张江项目 A04 对高增长           Financial                                                         Related to
                                                                           1,500,000.00    1,500,000.00   Other income
                                                            allocation                                                          income
技术企业资助款)
Provision for technology transformation funds and           Financial                                                         Related to
                                                                           1,576,000.00    2,300,000.00   Other income
subsequent grants (技术改造资金拨款及事后补奖)              allocation                                                          income
Provision for technology transformation funds and           Financial
                                                                           4,131,600.00    2,543,679.56   Other income Related to assets
subsequent grants (技术改造资金拨款及事后补奖)              allocation
Technology transformation of recycling system of            Financial
                                                                            397,818.48      397,818.48    Other income Related to assets
Acarbose project (阿卡波糖糖回收系统技术改造项目)           allocation
Special Fund and Encouraging funds for Energy Saving        Financial                                                         Related to
                                                                            352,000.00      289,500.00    Other income
and Emission Reduction (节能减排专项资金及奖励金)           allocation                                                          income
Scientific technology award and subsidy for
                                                            Financial                                                         Related to
technological innovative project (科学技术奖及科技创                       7,352,000.00    2,663,400.00   Other income
                                                            allocation                                                          income
新项目资助)
Patent (Intellectual Property) Support Fund (专利(知识     Financial                                                         Related to
                                                                            849,370.00      548,500.00    Other income
产权)资助资金)                                             allocation                                                          income
Reward Fund for Industry Growth and Production              Financial                                                         Related to
                                                                           5,050,000.00     667,700.00    Other income
Expansion (工业保值增长及增产奖励)                          allocation                                                          income
New industrialization development funds (新型工业化         Financial
                                                                            350,000.04      350,000.04    Other income Related to assets
发展资金)                                                   allocation
Industrial revitalisation supporting funds (产业振兴扶持    Financial
                                                                           1,158,000.00    1,158,000.00   Other income Related to assets
资金)                                                       allocation
                                                            Financial                                                         Related to
Industrial supporting funds (产业扶持资金)                                    13,000.00     944,100.00    Other income
                                                            allocation                                                          income
Employment Assurance and Re-employment and
Attraction to Graduates of Tertiary Academic Institutions   Financial                                                         Related to
                                                                           5,024,018.69    5,949,048.90   Other income
Subsidy (企业稳岗及再就业和吸纳高校毕业生补贴               allocation                                                          income
款)
New Scientific Research Institution Subsidy (新型科研       Financial
                                                                           2,000,000.00            0.00   Other income Related to assets
机构补助资金)                                               allocation
Enterprise Technology Center Innovation Capacity
                                                            Financial
Development (Antibody Laboratory) (企业技术中心创                           445,755.36      514,338.20    Other income Related to assets
                                                            allocation
新能力建设 (抗体药物试验室) )




                                                                  259
    Joincare Pharmaceutical Group                                                                                      Annual Report 2022


    Supporting subsidy for “Talents Plan” and subsidy for
                                                                  Financial                                                           Related to
    talents introduction and cultivation ( “人才计划”配套补                     646,759.03         583,774.23   Other income
                                                                  allocation                                                            income
    贴及引才育才补贴)
    Integrating Informatization and Industrialization Rewards     Financial                                                           Related to
                                                                                         0.00        500,000.00   Other income
    (两化融合奖励)                                                allocation                                                            income
    Incentive funds for expansion of export scale (扩大出口       Financial                                                           Related to
                                                                                  519,700.00         456,300.00   Other income
    规模奖励基金)                                                 allocation                                                            income
    Special funds for key leading enterprises in the 13th
                                                                  Financial                                                           Related to
    Five-Year Plan (2019) (十三五重点领军企业专项资金                                    0.00    14,133,300.00    Other income
                                                                  allocation                                                            income
    (2019 年)
                                                                  Financial                                                           Related to
    Subsidies for work-based training (以工代训补贴)                              848,400.00         395,000.00   Other income
                                                                  allocation                                                            income
                                                                  Financial                                                           Related to
    Subsidies for insurance fees (保险费用补贴)                                   200,000.00         609,243.30   Other income
                                                                  allocation                                                            income
    Special Funds for Promoting High-quality Economic             Financial
                                                                                  357,200.00      5,741,886.91    Other income Related to assets
    Development (促进经济高质量发展专项资金)                      allocation
    Special Funds for Promoting High-quality Economic             Financial                                                           Related to
                                                                                 3,540,020.00    11,578,756.00    Other income
    Development (促进经济高质量发展专项资金)                      allocation                                                            income
    Funds for joint R&D and industrialization of integrated
    platform for molecular diagnostics (集成一体化分子诊          Financial
                                                                                 1,368,367.87        127,715.81   Other income Related to assets
                                                                  allocation
    断平台的合作研发及产业化)
    Funds for industrial volatile organic pollution control       Financial                                                           Related to
                                                                                  628,000.00               0.00   Other income
    projects (工业挥发性有机污染治理项目资金)                     allocation                                                            income
    Achievement transfer of blood screening BCI nucleic
                                                                  Financial
    acid detection testing (血液筛查 BCI 核酸检测试剂成                          2,038,717.57        631,622.73   Other income Related to assets
                                                                  allocation
    果转化)
    COVID-19 emergency technology special emergency
                                                                  Financial
    fund and special grants for industrialization (新冠应急科                    1,084,784.35         26,694.08   Other income Related to assets
                                                                  allocation
    技攻关专项款及产业化项目补助金)
                                                                  Financial                                                           Related to
     “Specialized and new” subsidy ( “专精特新”补贴)                          175,000.00      1,200,000.00    Other income
                                                                  allocation                                                            income
    Hengqin Guangdong-Macao Deep Cooperation Zone
                                                                  Financial                                                           Related to
    Factory Rental Subsidy (横琴粤澳深度合作区厂房租金                                   0.00        690,024.00   Other income
                                                                  allocation                                                            income
    补贴)
    Zhuhai Investment Promotion Award (珠海市招商引资             Financial                                                           Related to
                                                                                         0.00        600,000.00   Other income
    奖)                                                           allocation                                                            income
    National Science and Technology Major Special Project
                                                                  Financial
    Subsidy Fund LZM009 (国家科技重大专项项目后补助                                      0.00     2,362,093.09    Other income Related to assets
                                                                  allocation
    资金 LZM009)
    Data-driven industrial chain collaboration platform
    demonstration project (数据驱动的产业链协同平台示             Financial
                                                                                         0.00        730,000.00   Other income Related to assets
                                                                  allocation
    范项目)
    Several Measures for Payment Enterprises to Overcome
    Difficulties in Response to the Novel Coronavirus
    Pneumonia Epidemic-Financial Support Project Funds            Financial                                                           Related to
                                                                                 6,093,000.00        381,000.00   Other income
                                                                  allocation                                                            income
    (应对新型冠状病毒肺炎疫情支付企业共渡难关的若
    干措施-金融支持项目资金)
    Project funds for promoting the development of the
    biomedical industry (促进生物医药产业发展用途项目             Financial                                                           Related to
                                                                                         0.00     7,665,180.00    Other income
                                                                  allocation                                                            income
    资金)
    Application of artificial intelligence in triptorelin long-
                                                                  Financial                                                           Related to
    acting microsphere preparation (人工智能在曲普瑞林长                                 0.00        800,000.00   Other income
                                                                  allocation                                                            income
    效微球制剂中的应用)
                                                                   Financial
    Others                                                                       2,271,603.34     2,584,330.85    Other income Related to assets
                                                                  allocation
                                                                   Financial                                                          Related to
    Others                                                                       4,847,038.25     7,044,647.21    Other income
                                                                  allocation                                                            income
                                                                  Financial
                              Total                                            245,335,140.69   286,842,932.33
                                                                  allocation

(3) Government grants using the net amount method to offset related costs

    None.

(4) Return of government grants

                                      Item                                        Amount                             Reason
    Research and development funds for new drug for Class I
    Treatment of Necrosis Factor in Human Tumour from                                                       Return the remaining funds
                                                                                      2,076,000.00
    Human Source (I 类治疗用人源化抗人肿瘤坏死因子 α 单                                                  after the project is completed
    克隆抗体新药研制资金)

                                                                        260
       Joincare Pharmaceutical Group                                                                                              Annual Report 2022


       China Postdoctoral Science Foundation subsidy funds (中国
                                                                                                   73,716.81                      Balance returned
       博士后科学基金会资助经费)



VI. Changes in the scope of consolidation

1. Disposal of subsidiaries

       None.

2. Set-up of subsidiaries

       The Company’s subsidiary, Jiaozuo Joincare Bio Technological Co., Ltd. (焦作健康元生物制品有限公司)
       together with Fenghuolun (Shanghai) Biotechnology Co., Ltd. (风火轮(上海) 生物科技有限公司) to
       established Jiaozuo Jianfeng Biotechnology Co., Ltd. on 5 August 2022, with a registered capital of RMB50
       million. Jiaozuo Joincare Bio Technological Co., Ltd. (焦作健康元生物制品有限公司) is holding 66.5%
       shares.

3. Change to scope of consolidation in the subsidiary Livzon Group

       The Company's subsidiary, Livzon Group's Subsidiaries Livzon Biotechnology Hong Kong Co., Ltd.
       established LIVZON BIOLOGICS (MALAYSIA) SDN. BHD. on January 12, 2022, with registered capital
       of Malaysia Ringgit 100, of which the Livzon Group's investment is Malaysia Ringgit 100 and accounts for
       its registered capital of 100%.

VII. Equity in other entities

1. Interests in subsidiaries

(1) Group structure

                                                             Main                                                       Shareholding %
                                Type of       Corporate                   Place of     Business                                             Acquisition
    Name of subsidiary                                    operating                                Registered capital
                              subsidiaries    Category                  registration    nature                                     Indire    method
                                                           location                                                      Direct
                                                                                                                                     ct

 Topsino Industries Limited        Wholly-
                                                Limited                                                                                        Set-up by
 (天诚实业有限公司)                 owned                 Hong Kong      Hong Kong      Business HKD896,933,973.00        100
                                               company                                                                                        investment
 (Topsino) )                     subsidiary

 Shenzhen Taitai Genomics
                                   Wholly-
 Inc. Co., Ltd. (深圳太太基                     Limited                                                                                        Set-up by
                                    owned                   Shenzhen       Shenzhen     Industry    RMB50,000,000.00      75        25
 因工程有限公司)(Taitai          subsidiary
                                               company                                                                                        investment
 Genomics) )

 Shenzhen Taitai
 Pharmaceutical Industry           Wholly-
                                                Limited                                                                                        Set-up by
 Co., Ltd. (深圳太太药业            owned                   Shenzhen       Shenzhen     Industry RMB100,000,000.00        100
                                               company                                                                                        investment
 有限公司) (Taitai               subsidiary
 Pharmaceutical)
 Health Investment                 Wholly-
                                                Limited  The British    The British                                                            Set-up by
 Holdings Ltd. (Health              owned                                            Investment         USD50,000.00                100
                                               company Virgin Islands Virgin Islands                                                          investment
 Investment)                     subsidiary

 Joincare Pharmaceutical           Wholly-
                                                Limited  The British    The British                                                            Set-up by
 Group Industry                     owned                                            Investment         USD 50,000.00               100
                                               company Virgin Islands Virgin Islands                                                          investment
 Co.,Ltd.(BVI) *                 subsidiary

 Joincare Pharmaceutical
                                   Wholly-
 Group Industry                                 Limited      Cayman          Cayman                                                            Set-up by
                                    owned                                             Investment        USD 50,000.00               100
 Co.,Ltd.(CAYMAN                               company        Islands         Islands                                                         investment
                                 subsidiary
 ISLANDS)

 Xinxiang Haibin                   Wholly-
                                                Limited        Henan          Henan                                                            Set-up by
 Pharmaceutical Co.,                owned                                               Industry RMB170,000,000.00                  100
                                               company       Xinxiang       Xinxiang                                                          investment
 Ltd.(Xinxiang Haibin) (新       subsidiary




                                                                              261
      Joincare Pharmaceutical Group                                                                                                Annual Report 2022


                                                               Main                                                      Shareholding %
                                 Type of       Corporate                   Place of     Business                                             Acquisition
   Name of subsidiary                                       operating                               Registered capital
                               subsidiaries    Category                  registration    nature                                     Indire    method
                                                             location                                                     Direct
                                                                                                                                      ct

乡海滨药业有限公司(新
乡海滨) )

Shenzhen Fenglei Electric
Power Investment Co.,               Wholly-
                                                 Limited                                                                                        Set-up by
Ltd. (深圳市风雷电力投               owned                    Shenzhen      Shenzhen Investment RMB100,000,000.00          100
                                                company                                                                                        investment
资有限公司) (Fenglei              subsidiary
Electric Power) )

Jiaozuo Joincare Bio
Technological Co., Ltd.             Wholly-
                                                 Limited                                                                                        Set-up by
(焦作健康元生物制品有                owned               Henan Jiaozuo Henan Jiaozuo     Industry RMB500,000,000.00        75        25
                                                company                                                                                        investment
限公司) (Jiaozuo                  subsidiary
Joincare) )

Shanghai Frontier Health
Pharmaceutical
Technology Co., Ltd. (上                         Limited                                                                                        Set-up by
                                Subsidiaries                  Shanghai       Shanghai    Industry    RMB50,000,000.00      65
海方予健康医药科技有                            company                                                                                        investment
限公司)(Shanghai
Frontier)

Shenzhen Taitai Biological
                                    Wholly-
Technology Co., Ltd (深圳                        Limited                                                                                        Set-up by
                                     owned                    Shenzhen      Shenzhen     Industry     RMB5,000,000.00      100
太太生物科技有限公司)             subsidiary
                                                company                                                                                        investment
(Taitai Biological)

Guangzhou Joincare
Respiratory Medicine
Engineering Technology                           Limited                                                                                        Set-up by
Co., Ltd. (广州健康元呼         Subsidiaries                Guangzhou      Guangzhou     Industry    RMB10,000,000.00                26
                                                company                                                                                        investment
吸药物工程技术有限公
司) (Joincare Respiratory )

Guangdong Taitai
Forenstic Test Institute (广        Wholly-
                                                   Other                                                                                        Set-up by
                                     owned                    Shenzhen      Shenzhen     Business             RMB0.00                100
东太太法医物证司法鉴                         organization                                                                                      investment
                                  subsidiary
定所(鉴定所) )

Joincare Haibin
Pharmaceutical Co., Ltd.            Wholly-
                                                 Limited                                                                                        Set-up by
                                     owned                    Shenzhen      Shenzhen     Industry RMB500,000,000.00        25        75
(健康元海滨药业有限公                           company                                                                                        investment
                                  subsidiary
司) (Joincare Haibin) )

Shenzhen Haibin                                                                                                                                 Business
Pharmaceutical Co., Ltd.            Wholly-                                                                                                  combination
                                                 Limited
                                     owned                    Shenzhen      Shenzhen     Industry RMB700,000,000.00       97.87      2.13      not under
(深圳市海滨制药有限公                           company
                                  subsidiary                                                                                                    common
司) (Haibin Pharma)                                                                                                                              control

Joincare Daily-Use &                                                                                                                            Business
Health Care Co., Ltd. (健           Wholly-                                                                                                  combination
                                                 Limited
                                     owned                    Shenzhen      Shenzhen     Business    RMB25,000,000.00      80        20        not under
康元日用保健品有限公                            company
                                  subsidiary                                                                                                    common
司) (Joincare Daily-Use)                                                                                                                         control

Health Pharmaceuticals                                                                                                                          Business
                                    Wholly-                                                                                                  combination
(China) Limited (健康药                          Limited
                                     owned                      Zhuhai         Zhuhai    Industry    HKD73,170,000.00                100       not under
业(中国) 有限公司)                subsidiary
                                                company
                                                                                                                                                common
(Health China)                                                                                                                                   control

Livzon Pharmaceutical                                                                                                                           Business
                                                                                                                                             combination
Group Inc. (丽珠医药集团                     Joint-stock
                                Subsidiaries                    Zhuhai         Zhuhai    Industry RMB935,552,687.00       23.66     21.11      not under
股份有限公司) (Livzon                          company
                                                                                                                                                common
Group) * Note 1 & 2                                                                                                                              control

Hong Kong Health                                                                                                                                Business
Pharmaceutical Industry             Wholly-                                                                                                  combination
                                                 Limited
                                     owned                  Hong Kong     Hong Kong Investment           HKD10,000.00                100       not under
Company Limited (香港健                         company
                                  subsidiary                                                                                                    common
康药业有限公司)                                                                                                                                  control




                                                                               262
      Joincare Pharmaceutical Group                                                                                                  Annual Report 2022


                                                             Main                                                         Shareholding %
                               Type of       Corporate                     Place of     Business                                               Acquisition
   Name of subsidiary                                     operating                                 Registered capital
                             subsidiaries    Category                    registration    nature                                       Indire    method
                                                           location                                                         Direct
                                                                                                                                        ct
                                                                                                                                                   Business
Health Pharmaceutical             Wholly-                                                                                                       combination
                                               Limited
Industry Company Limited           owned                   Hong Kong      Hong Kong Investment           HKD10,000.00                  100        not under
                                              company
(健康药业有限公司)              subsidiary                                                                                                         common
                                                                                                                                                    control

Shenzhen Hiyeah Industry                                                                                                                           Business
                                  Wholly-                                                                                                       combination
Co., Ltd (深圳市喜悦实业                       Limited
                                   owned                     Shenzhen       Shenzhen     Business RMB178,000,000.00         97.58      2.42       not under
有限公司) (Shenzhen             subsidiary
                                              company
                                                                                                                                                   common
Hiyeah) )                                                                                                                                           control

                                                                                                                                                   Business
Guangzhou Hiyeah                  Wholly-                                                                                                       combination
                                               Limited
Industry Co., Ltd. (广州市         owned                   Guangzhou       Guangzhou     Industry     RMB3,000,000.00                  100        not under
                                              company
喜悦实业有限公司)               subsidiary                                                                                                         common
                                                                                                                                                    control

                                                                                                                                                   Business
Zhongshan Renhe Health            Wholly-                                                                                                       combination
                                               Limited
Products Co., Ltd. (中山市         owned                   Zhongshan       Zhongshan     Industry       RMB500,000.00                  100        not under
                                              company
仁和保健品有限公司)             subsidiary                                                                                                         common
                                                                                                                                                    control
                                                                                                                                                   Business
Shenzhen Jiekang Health           Wholly-                                                                                                       combination
                                               Limited
Care Co., Ltd. (深圳市捷           owned                     Shenzhen       Shenzhen     Industry     RMB4,000,000.00                  100        not under
                                              company
康保健有限公司 )                subsidiary                                                                                                         common
                                                                                                                                                    control

Joincare (Guangdong)
Special medicine Food             Wholly-
                                               Limited                                                                                            Set-up by
Co., Ltd. (健康元(广东)            owned                    Shaoguan        Shaoguan     Industry    RMB20,000,000.00        100
                                              company                                                                                            investment
特医食品有限公司)               subsidiary
(Joincare Special Food)
Henan Joincare Biology
                                               Limited                                                                                            Set-up by
Medical Research Institute    Subsidiaries                     Jiaozuo        Jiaozuo    Industry    RMB100,000,000.0                 70.13
                                              company                                                                                            investment
Co., Ltd.* Note 3

Jiaozuo Jianfeng
                                               Limited                                                                                            Set-up by
Biotechnology Co., Ltd.       Subsidiaries                     Jiaozuo        Jiaozuo    Industry     RMB50,000,000.0                  66.5
                                              company                                                                                            investment
*Note 4


      *Note 1: Shanghai Frontier Health Pharmaceutical Technology Co., Ltd. (上海方予健康医药科技有限公司) and the Company's subsidiary Livzon
      Group established Shanghai Liyu Biomedical Technology Co., Ltd. (上海丽予生物医药技术有限责任公司) on 30 March 2021. Livzon Group holds
      55% of the shares and Shanghai Frontier Health Pharmaceutical Technology Co., Ltd holds 45%.

      *Note 2: Zhuhai Livzon Biotechnology Co., Ltd. (珠海市丽珠生物医药科技有限公司) is a subsidiary within the scope of Livzon Group's consolidation.
      It was originally 100% indirectly held by Livzon Group. In the current period, due to the restructuring of the shareholding structure of the subsidiary,
      Livzon Group holds 51% of its shares, the Company holds 33.07% of the shares, YF Pharmab Limited holds 8.43% of the shares, and Hainan
      Lishengjuyuan Investment Partnership (Limited Partnership) (海南丽生聚源投资合伙企业(有限合伙)) holds 7.50%.

      *Note 3: Henan Joincare Biomedical Research Institute Co., Ltd. (河南省健康元生物医药研究院有限公司) is a joint venture established on 26 October
      2020 by Jiaozuo Joincare Biological Products Co., Ltd. (焦作健康元生物制品有限公司), a subsidiary of the Company, and Livzon Group Xinbeijiang
      Pharmaceutical Co., Ltd. (丽珠集团新北江制药股份有限公司), a subsidiary of the Company’s Livzon Group. Jiaozuo Joincare Biological Products
      Co., Ltd. holds 51% of the shares. The investee completed its industrial and commercial registration on 26 October 2020.

      *Note 4: Jiaozuo Jianfeng Biotechnology Co., Ltd. Is jointed established by the Company’s subsidiary, Jiaozuo Joincare Bio Technological Co., Ltd. (焦
      作健康元生物制品有限公司) and Fenghuolun (Shanghai) Biotechnology Co., Ltd. (风火轮(上海) 生物科技有限公司) on 5 August 2022. Jiaozuo
      Joincare Bio Technological Co., Ltd. (焦作健康元生物制品有限公司) holds 66.5% shares.

      Subsidiaries not included in the scope of consolidation in the current period:

      Name of subsidiary                                         Registered capital                 Actual investment                   Interest held

      Guangzhou Hiyeah Industry Co., Ltd. (广州
                                                                              3,000,000.00                        3,000,000.00                 100%
      市喜悦实业有限公司)

      Zhongshan Renhe Health Products Co., Ltd.                                 500,000.00                          500,000.00                 100%

                                                                               263
     Joincare Pharmaceutical Group                                                                                                                     Annual Report 2022



     (中山市仁和保健品有限公司)

     Shenzhen Jiekang Health Care Co., Ltd. (深
                                                                                      4,000,000.00                             4,000,000.00                      100%
     圳市捷康保健有限公司 )

     Guangzhou Hiyeah Industry Co., Ltd. (广州市喜悦实业有限公司), Zhongshan Renhe Health Products Co.,
     Ltd. (中山市仁和保健品有限公司) are wholly-owned subsidiaries of Shenzhen Hiyeah. They entered the
     liquidation process in 2008, and has been out of business for many years, and completed the tax cancellation
     procedures, so they were not included in the scope of the consolidated.

     Shenzhen Jiekang Health Care Co., Ltd. (深圳市捷康保健有限公司) was wholly-owned subsidiary of
     Shenzhen Hiyeah. It had entered the liquidation process in 2008, and has been out of business for many years,
     and completed the tax cancellation procedures, and it was approved and cancelled by Shenzhen Market
     Supervision and Administration Bureau on May 30, 2022.

(2) Significant non-wholly owned subsidiaries

                                                                             Profit or loss                                                         Balance of minority
             Name of               Shareholding of                                                                 Dividend paid to
                                                                  attributable to minority                                                           interests at period
            subsidiary             minority interest                                                               minority interest
                                                                                   interest                                                                         end
       Livzon Group                          55.2266%                      1,053,970,833.13                          670,811,289.90                      7,663,254,428.90

(3) Principal financial information of significant non-wholly owned subsidiaries

                                                                                         Closing balance
    Name of
   subsidiary                                         Non-current                                                                      Non-current
                        Current assets                                        Total assets             Current liabilities                                      Total liabilities
                                                        assets                                                                          liabilities
   Livzon
                       16,987,297,040.38           7,877,528,325.85          24,864,825,366.23           7,396,664,920.29            2,531,908,854.22           9,928,573,774.51
   Group

     Continued (1) :

                                                                                         Beginning balance
       Name of
      subsidiary                                        Non-current                                                                     Non-current
                           Current assets                                       Total assets           Current liabilities                                      Total liabilities
                                                          assets                                                                         liabilities
     Livzon
                          14,673,096,594.67           7,698,818,996.15       22,371,915,590.82           6,925,068,067.24            1,135,822,729.96           8,060,890,797.20
     Group

     Continued (2) :

                                               Current year                                                                            Prior year
   Name of
   subsidia                                                   Total        Cash flows from                                                         Total
      ry                                                                                                                                                          Cash flows from
               Operating income       Net profit          comprehensive       operating        Operating income         Net profit             comprehensive
                                                                                                                                                                 operating activities
                                                             income           activities                                                          income
   Livzon
               12,629,579,047.66   1,955,540,213.06     2,084,847,720.65    2,772,671,295.03   12,063,863,272.98    1,952,101,168.93         1,834,898,051.39   1,902,328,139.03
   Group


(4) Changes in share of owners' equity in subsidiaries and still controls the subsidiaries

       None.




                                                                                        264
     Joincare Pharmaceutical Group                                                                              Annual Report 2022


2. Interests in joint arrangement or associates

(1) Significant associates

       Joint venture or associate         Main                                             Shareholding (%)              Accounting
                                                       Place of            Business
         Name of other related         operating                                                                        treatment of
                                                     registration           nature              Direct   Indirect
               parties                  location                                                                         investment

       Associates
       Jiaozuo Jinguan Jiahua
       Electric Power Co., Ltd.            Henan
                                                           Henan       For electricity
                                          Jiaozuo                                                 0.00        49        Equity method
       (焦作金冠嘉华电力有限                         Jiaozuo City         production
                                             City
       公司)
       Tianjin Tongrentang
                                                                      Pharmaceutical
       Group Co., Ltd. (天津同             Tianjin         Tianjin                                0.00        40        Equity method
                                                                       manufacturing
       仁堂集团股份有限公司)

(2) Main financial information of significant associates

   ①Jiaozuo Jinguan Jiahua Electric Power Co., Ltd. (焦作金冠嘉华电力有限公司)

                                                                 Jiaozuo Jinguan Jiahua Electric Power Co., Ltd.
                                                                           (焦作金冠嘉华电力有限公司)
                           Item
                                                              Closing balance/ Current         Beginning balance/ Prior
                                                                      year                             year
     Current assets                                                         1,034,890,763.04                         900,929,930.10
       Including: Cash and cash equivalents                                  193,286,823.41                          151,817,021.98
     Non-current assets                                                      274,836,800.49                          295,290,603.34
     Total assets                                                           1,309,727,563.53                        1,196,220,533.44
     Current liabilities                                                     734,194,376.70                          621,231,810.54
     Non-current liabilities                                                  12,419,097.25                           13,660,568.14
     Total liabilities                                                       746,613,473.95                          634,892,378.68
     Net assets                                                              563,114,089.58                          561,328,154.76
      Including: Minority interests                                                      0.00                                   0.00
         Owners’ equity attributable to parent
                                                                             563,114,089.58                          561,328,154.76
     company
     Net assets share calculated by shareholding                             275,925,903.89                          275,050,795.83
     Adjustments
      Including: Goodwill
        Unrealized profit or loss in internal
     transactions
       Provision for impairment
       Others                                                                   9,612,591.63                           9,569,113.18
     Carrying value of equity investment in
                                                                             285,538,495.52                          284,619,909.02
     associates
     Fair value of publicly quoted equity
     investments

     Continued:




                                                                     265
    Joincare Pharmaceutical Group                                                                             Annual Report 2022


                                                              Jiaozuo Jinguan Jiahua Electric Power Co., Ltd.
                                                                        (焦作金冠嘉华电力有限公司)
                          Item
                                                           Closing balance/ Current       Beginning balance/ Prior
                                                                    year                           year
    Operating income                                                     1,100,595,142.50                     702,123,322.31
    Financial expenses                                                     16,069,876.59                       14,968,954.50
    Income tax expenses                                                        15,013.60                        -1,540,629.99
    Net profit                                                              1,785,934.82                       -65,176,444.97
    Net profit from discontinued operations
    Other comprehensive income
    Total comprehensive income                                              1,785,934.82                       -65,176,444.97
    Net cash flows from operating activities                              132,858,948.24                      -135,982,225.15
    Dividends received from joint ventures in the
    current period

  ②Tianjin Tongrentang Group Co., Ltd. (天津同仁堂集团股份有限公司)

                                                                                 Tianjin Tongrentang Group Co., Ltd.
                                      Item                                         (天津同仁堂集团股份有限公司)
                                                                                                 2022.12.31
      Owners’ equity attributable to parent company                                                            570,306,493.51
      Net assets share calculated by shareholding                                                               228,122,597.40
      Adjustments
       Including: Goodwill                                                                                      498,457,683.68
      Carrying value of equity investment in associates                                                         726,580,281.08
      Fair value of publicly quoted equity investments

    Continued:

                                                                                 Tianjin Tongrentang Group Co., Ltd.
                                     Item                                           (天津同仁堂集团股份有限公司)
                                                                                               Current year
      Operating income                                                                                        1,086,062,042.02
      Dividends received by the company from associates in the current
                                                                                                                111,980,000.00
      period

    The Company calculates the share of assets of associate based on the shareholding for the amount attributable
    to the parent company in the consolidated financial statements. The amounts in the consolidated financial
    statements of associates take into account the fair value of identifiable net assets and liabilities of associates
    at the time of acquisition and the impact of unified accounting policies. the above data is the preliminary
    results announcement of Tianjin Tongrentang.

(3) Summary of financial information of other insignificant associates

                                                                 Closing balance/                   Beginning balance/
                             Item
                                                                  Current year                          Prior year
    Associates:
    Total carrying amount of investment                                      407,763,817.99                      1,134,729,545.83
    The following amount are calculated on the basis of
    shareholding ratio
    Net profit                                                                -11,360,486.63                       42,217,479.63



                                                               266
     Joincare Pharmaceutical Group                                                                    Annual Report 2022


     Other comprehensive income                                            527,718.52                      14,789,928.17
     Total comprehensive income                                         -10,832,768.11                     57,007,407.80

(4) Significant limitations on the ability of joint ventures or associates to transfer funds to the Company

     None.

VIII. Risks Management of Financial Instruments

     The major financial instruments of the Company include cash, bills receivable and accounts receivable, other
     receivables, non-current assets due within one year, other current assets, financial assets held for trading,
     other equity instrument investments, bills payable and accounts payable, other payables, short-term
     borrowings, financial liabilities held for trading, non-current liabilities due within one year, long-term
     borrowings and long-term payables. The details of these financial instruments are disclosed in the respective
     notes. The financial risk of these financial instruments and financial management policies used by the
     Company to minimize the risk are disclosed as below. The management of the Company manages and
     monitors the exposure of these risks to ensure the above risks are controlled in the limited range.

1. Management objectives and policies of risks

     The operation activities of the Company are subject to various financial risks: market risks (mainly including
     foreign exchange risks and interest rate risks), credit risks and liquidity risks. The Company formulates an
     overall risk management plan with respect to the unforeseeability of the financial market in order to minimise
     the potential adverse impacts on the financial performance of the Company.

(1) Foreign exchange risks

     The Company conducts its operation primarily in China. Substantially all of the transactions were
     denominated and settled in Renminbi. However, the Company still has certain imports and exports businesses
     regarding APIs and diagnostic reagents that are settled in U.S. dollar and Japanese Yen. The Company’s
     businesses outside China (mainly in Hong Kong, India, Europe) are settled in Hong Kong dollars, U.S. dollar
     and Eurodollar. In addition, the Company will have foreign currency loans according to the operating needs.
     In respect of the above, the Company still exposes to certain foreign exchange risks. Taking into account the
     foreign exchange risks acceptable by the Company, the Company adopted Derivative instruments to control
     foreign exchange risk. However, as to the foreign exchange risk in loans, the Company shall closely monitor
     the trend of the exchange rate of Renminbi, and timely adjust the extent of borrowings, so as to minimise its
     risks.

     Financial assets and liabilities in foreign currencies held by the Company expressed in Renminbi are stated
     below:

     ① As at 31 December 2022

                                                                                                       Unit: RMB 1,000

                 Item                HKD            USD           EUR           JPY          GBP      MOP        CHF
     Financial assets in foreign
     currency -
     Cash and bank balances          689,008.76   1,795,183.72     702.84      18,052.98      16.29   4,272.78      0.00
     Financial assets held for
                                      87,193.75           0.00          0.00          0.00     0.00       0.00      0.00
     trading
     Accounts receivable                   0.00    498,180.41           0.00          0.00     0.00   1,097.96      0.00
     Other receivables                 2,849.00           0.15          0.00          0.00     0.00     504.53      0.00
     Other current assets                  0.00     92,815.74           0.00          0.00     0.00       0.00      0.00
     Other equity instruments
                                     524,464.51           0.00          0.00          0.00     0.00       0.00      0.00
     investment


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     Joincare Pharmaceutical Group                                                                                 Annual Report 2022


               Subtotal:             1,303,516.02   2,386,180.02        702.84         18,052.98       16.29        5,875.27         0.00
     Financial liabilities in
                                             0.00           0.00             0.00            0.00          0.00           0.00       0.00
     foreign currency -
     Short-term loans                        0.00      13,464.86             0.00            0.00          0.00           0.00
     Accounts payable                        0.00       3,569.18         42.05         14,627.29           0.00           0.00     141.89
     Other payables                     2,583.45       27,967.54             0.00            0.00          0.00           0.00       0.00
               Subtotal:                2,583.45       45,001.58         42.05         14,627.29           0.00           0.00     141.89

     ② As at 31 December 2021

                                                                                                                    Unit: RMB 1,000

                  Item                  HKD                 USD                EUR            JPY                 GBP            MOP
     Financial assets in foreign
     currency -
     Cash and bank balances               516,034.78        1,296,568.06            559.42    2,406.62              16.70        1,121.33
     Financial assets held for
                                          163,071.45                  0.00            0.00          0.00                0.00         0.00
     trading
     Accounts receivable                        0.00          579,062.08       4,493.18             0.00                0.00     2,824.85
     Other receivables                      2,712.73                  0.00            0.00          0.00                0.00      461.23
     Other equity instruments
                                          480,531.75                  0.00            0.00          0.00                0.00         0.00
     investment
               Subtotal:                1,162,350.71        1,875,630.14       5,052.60       2,406.62              16.70        4,407.41
     Financial liabilities in
                                                0.00                  0.00            0.00          0.00                0.00         0.00
     foreign currency -
     Accounts payable                           0.00                213.29           40.90          0.00                0.00       11.01
     Other payables                         2,503.18           16,034.63              0.00          0.00                0.00         0.00
               Subtotal:                    2,503.18           16,247.92             40.90          0.00                0.00       11.01

     As at 31 December 2022, in respect of the Company’s financial assets and liabilities denominated in foreign
     currencies such as Hong Kong dollar, U.S. dollar, Euro, Japanese Yen and Macau dollar, should the value of
     RMB appreciate or depreciate by 5% against foreign currencies such as Hong Kong dollar, U.S. dollar, Euro,
     Japanese Yen and Macau dollar, and other factors remain unchanged, the Company would be subject to an
     increase or decrease in profit of approximately RMB182,597.36 (31 December 2021: approximately
     RMB151,553,060).

(2) Interest rate risk

     The Company’s exposures to interest rate risk are mainly arising from interest-bearing liabilities such as
     bank borrowings. The interest rates are affected by the macro monetary policies of China, hence the Company
     will face the risks arising from fluctuation of interest rates in the future.

     The finance department of the head office of the Company continues to monitor the level of interest rate of
     the Company. The rise in the interest rate will increase the cost of additional interest-bearing liabilities and
     the interest expenses of the Company’s outstanding interest-bearing liabilities of which the interests are
     calculated at floating rates, and impose material adverse impact on the financial results of the Company. The
     management will make timely adjustment based on the updated market conditions. The directors of the
     Company consider that the future changes in the interest rate will have no material adverse impact on the
     operating results of the Company.

(3) Credit risk

     Credit risk is primarily attributable to cash and cash equivalents, restricted funds, accounts receivables and
     other receivables. In respect of cash at banks, they were placed at several banks with good reputations, for

                                                              268
     Joincare Pharmaceutical Group                                                                      Annual Report 2022


     which the credit risk was limited. In respect of receivables, the Company shall assess the credit limit granted
     to customers for credit purpose. Moreover, as the customer base of the Company is large, the credit risk on
     accounts receivables is not concentrated. In terms of bills receivable settlement, external payments are settled
     with bills receivable with priority and most of the remaining bills are high-quality bills with maturity within
     three months; thus none expected major credit risk exits. In addition, the provision made on the impairment
     of accounts receivables and other receivables are adequate to manage the credit risk.

     Among the accounts receivables of the Company, the accounts receivable of the top five customers accounted
     for 11.98% (31 December 2021: 11.60%); among the other receivables of the Company, the other receivables
     of the top five customers accounted for 46.23% (31 December 2021: 60.63%).

(4) Liquidity risk

     The Company adopts prudent liquidity risk management for the sufficient supply of monetary funds and
     liquidity. It secures readily available credit loans from banks mainly by maintaining adequate monetary funds
     and banking facilities. Apart from indirect financing from banks, a number of financing channels were
     available, such as direct financing by inter-bank market including short-term financing bills and medium-
     term financing bills, corporate bonds etc. These instruments can effectively reduce the effects of scale of
     financing and the macro monetary policies of China on indirect bank financing, which shall secure adequate
     funds in a flexible manner.

     As at the date of the balance sheet, the contractual cash flows of financial assets and financial liabilities are
     presented below by term of maturity:

     ① As at 31 December 2022

                                                                                             Over 5
                 Item              Within a year        1-2 years         2-5 years                          Total
                                                                                             years
     Financial assets:
     Cash and bank balances        14,808,488,110.96             0.00                 0.00       0.00    14,808,488,110.96
     Financial assets held for
                                     109,015,664.98              0.00                 0.00       0.00       109,015,664.98
     trading
     Notes receivable               1,959,985,016.85             0.00                 0.00       0.00     1,959,985,016.85
     Accounts receivable            3,103,758,850.15             0.00                 0.00       0.00     3,103,758,850.15
     Other receivables                52,535,740.14              0.00                 0.00       0.00        52,535,740.14
     Other current assets            104,859,166.96              0.00                 0.00       0.00       104,859,166.96
              Subtotal:            20,138,642,550.04             0.00                 0.00       0.00    20,138,642,550.04

     Financial liabilities:
     Short-term loans               2,126,050,615.06             0.00                 0.00       0.00     2,126,050,615.06
     Financial liabilities held
                                         755,634.43              0.00                 0.00       0.00          755,634.43
     for trading
     Notes payable                  1,635,906,989.22             0.00                 0.00       0.00     1,635,906,989.22
     Accounts payable                943,905,580.91              0.00                 0.00       0.00       943,905,580.91
     Other payables                 3,680,334,360.88             0.00                 0.00       0.00     3,680,334,360.88
     Other current liabilities        83,541,891.93              0.00                 0.00       0.00        83,541,891.93
     Non-current liabilities due
                                      63,077,260.98              0.00                 0.00       0.00        63,077,260.98
     within one year
     Lease liabilities                          0.00    14,509,839.81       8,972,646.26         0.00        23,482,486.07
     Long term loans                            0.00   907,182,927.81   2,323,661,115.07         0.00     3,230,844,042.88
     Subtotal:                      8,533,572,333.41   921,692,767.62   2,332,633,761.33         0.00    11,787,898,862.36




                                                                269
      Joincare Pharmaceutical Group                                                                          Annual Report 2022


     ② As at 31 December 2021

                Item              Within a year        1-2 years           2-5 years          Over 5 years        Total
    Financial assets:
    Cash and bank balances        11,729,230,390.98                0.00                0.00           0.00     11,729,230,390.98
    Financial assets held for
                                      184,638,344.31               0.00                0.00           0.00       184,638,344.31
    trading
    Notes receivable               1,977,286,022.02                0.00                0.00           0.00      1,977,286,022.02
    Accounts receivable            2,853,655,551.54                0.00                0.00           0.00      2,853,655,551.54
    Other receivables                  88,053,825.12               0.00                0.00           0.00         88,053,825.12
    Non-current assets due
                                         317,381.23                0.00                0.00           0.00           317,381.23
    within one year
    Long-term receivables                       0.00      266,904.13                   0.00           0.00           266,904.13
             Subtotal:            16,833,181,515.20       266,904.13                   0.00           0.00     16,833,448,419.33

    Financial liabilities:
    Short-term loans               2,518,484,835.09                0.00                0.00           0.00      2,518,484,835.09
    Financial liabilities held
                                         143,302.24                0.00                0.00           0.00           143,302.24
    for trading
    Notes payable                  1,582,386,767.93                0.00                0.00           0.00      1,582,386,767.93
    Accounts payable                  871,553,210.51               0.00                0.00           0.00       871,553,210.51
    Other payables                 3,292,407,989.79                0.00                0.00           0.00      3,292,407,989.79
    Non-current liabilities due
                                       91,576,066.33               0.00                0.00           0.00         91,576,066.33
    within one year
    Lease liabilities                           0.00    13,186,526.27      11,885,268.05              0.00         25,071,794.32
    Long term loans                             0.00   466,780,252.78     360,000,000.00              0.00       826,780,252.78
             Subtotal:             8,356,552,171.89    479,966,779.05     371,885,268.05              0.00      9,208,404,218.99


2. Capital management

      The capital management policies are made to keep the continuous operation of the Company, to enhance the
      return to shareholders, to benefit other stakeholders and to maintain the best capital structure to minimize the
      cost of capital.

      For the maintenance or adjustment of the capital structure, the Company might adjust financing method, the
      amount of dividends paid to shareholders, return capital to shareholders, issue new shares and other equity
      instruments or make an asset disposal to reduce the liabilities.

      The Company monitors the capital structure with gearing ratio (calculated by dividing total liabilities by total
      assets). On 31 December 2022, the Company’s gearing ratio is 38.37% (31 December 2021: 35.12%).

3. Transfer of financial assets

(1) Financial assets which are transferred but have not been derecognised in their entirety

     None.

(2) Financial assets which have been transferred and ceased to be recognised but still have involvement with the
transferor

     As at 31 December 2022, the Company discounted a banker's acceptance bill to the bank of
     RMB1,190,002,804.98 (previous period: RMB76,908,320.00). Since the principal risks and rewards, such as


                                                              270
      Joincare Pharmaceutical Group                                                                        Annual Report 2022


      interest rate risks associated with these bankers' acceptances, have been transferred to the banks, the Company
      derecognizes discounted unmatured bankers' acceptance bills. According to the discount agreement, if the
      banker's acceptance bill is not accepted when due, the bank has the right to require the Company to pay the
      outstanding balance. As a result, the Company continued to engage in discounted bankers' acceptances, which
      amounted to RMB422,899,944.56 (31 December 2021: RMB67,908,033.05) as at 31 December 2022.

      As at 31 December 2022, the carrying value of the Company's unexpired bankers' acceptance bills endorsed
      to suppliers for settlement of accounts payable was RMB542,620,475.62 (31 December 2021:
      RMB186,290,992.91) and no outstanding commercial acceptance bills endorsed to suppliers for settlement of
      accounts payable (31 December 2021: Nil). In accordance with the Negotiable Instruments Law, the holders
      of the bills have a right of recourse against the Company if payment is refused by the bank of acceptance (the
      “Continuing Involvement”). The maturity date is within 1 to 6 months as at 31 December 2022, in the opinion
      of the Company, the Company has transferred substantially all risks and rewards. Accordingly, their full
      carrying amounts and the corresponding account payables have been derecognised. The maximum loss and
      the undiscounted cash flows from the Continuing Involvement and repurchasing is equal to their carrying
      amounts. In the opinion of the Company, the fair values of the Continuing Involvement are not significant.

      During the year ended 31 December 2022, no gain or loss was generated by the Company on the date of
      transfer of the bills. The Company had no current or accumulated gain or loss arising from the continuing
      involvement in financial assets which had been derecognised. The endorsement was incurred evenly
      throughout the period.

IX. Fair value

      The level in which fair value measurement is categorised is determined by the level of the fair value hierarchy
      of the lowest level input that is significant to the entire fair value measurement. The levels are defined as
      follows:

      Level 1 inputs: unadjusted quoted prices in active markets that are observable at the measurement date for
      identical assets or liabilities.

      Level 2 inputs: inputs other than Level 1 inputs that are either directly or indirectly observable for
      underlying assets or liabilities.

      Level 3 inputs: inputs that are unobservable for underlying assets or liabilities.

(1) Items and amounts measured at fair value

      As at 31 December 2022, the assets and liabilities measured at fair value are listed as follows according to
      the above three levels:

                                                 Level 1 fair          Level 2 fair
                                                                                      Level 3 fair value
                      Item                         value                 value                                    Total
                                                                                       measurement
                                                measurement           measurement
  I. Recurring fair value measurement
  (1) Financial assets held for trading         103,583,153.41         5,432,511.57                 0.00        109,015,664.98
    1.debt instruments investment                   934,289.94                 0.00                 0.00            934,289.94
    2.equity instruments investment             102,648,863.47                 0.00                 0.00        102,648,863.47
     3.Derivative financial assets                        0.00         5,432,511.57                 0.00          5,432,511.57
  (2) Other equity instruments investment         9,615,483.94                 0.00    1,184,343,395.11       1,193,958,879.05
  Total assets measured at fair value on a
                                                113,198,637.35         5,432,511.57    1,184,343,395.11       1,302,974,544.03
  recurring basis
  (3) Financial liabilities held for trading
     Derivative financial liabilities                     0.00           755,634.43                 0.00            755,634.43
  Total liabilities measured at fair value on
                                                          0.00           755,634.43                 0.00            755,634.43
  a recurring basis

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     Joincare Pharmaceutical Group                                                                                Annual Report 2022


                                                   Level 1 fair            Level 2 fair
                                                                                             Level 3 fair value
                        Item                         value                   value                                       Total
                                                                                              measurement
                                                  measurement             measurement
 II. Non-recurring fair value measurement
 Assets held-for-sale                                            0.00               0.00                   0.00                  0.00
 Total assets measured at fair value on a
                                                                 0.00               0.00                   0.00                  0.00
 non-recurring basis
 Total liabilities measured at fair value on
                                                                 0.00               0.00                   0.00                  0.00
 a non-recurring basis

     During the year ended 31 December 2022, the Company’s investment LUNGLIFE AI, INC. was listed on
     the London Stock Exchange, as a result, the fair value measurement of this investment in other equity
     instruments transferred from level 3 to level 1; except for this investment in other equity instruments, tthere
     were no transfers of the fair value measurements between level 1 and level 2 and no transfers into or out of
     level 3.

     For the items in level 1 fair value measurement which listed on the Shanghai Stock Exchange, Shenzhen
     Stock Exchange, Hong Kong Stock Exchange or the United States, their fair value is determined based on
     the closing price on the last trading day of the reporting period.

     For the items in level 2 fair value measurement which uses valuation techniques and qualitative and
     quantitative information of important parameters to determine the fair value. For derivative financial
     instruments such as foreign exchange forward contracts, the fair value is determined based on the quoted
     forward exchange rate corresponding to the expiring contract.

     For the items in level 3 fair value measurement uses valuation techniques and qualitative and quantitative
     information of important parameters to determine the fair value. For some other equity instruments held, the
     fair value is based on the cost or the present value of the estimated future net cash flow as the best estimate.

(2) Relevant information of level 2 fair value measurement

                Content              Fair value as at 2022.12.31                           Valuation techniques
                                                                        Calculated and determined based on the quoted forward
      Derivative financial assets                   5,432,511.57
                                                                        exchange rate corresponding to the expiring contract
      Derivative financial                                              Calculated and determined based on the quoted forward
                                                      755,634.43
      liabilities                                                       exchange rate corresponding to the expiring contract

(3) Quantitative information of important unobservable input values used in level 3 of fair value measurement

                                                                                  Fair value as at
                                     Content                                                               Valuation techniques
                                                                                    2022.12.31
     Other equity instrument investments- (Shanghai Yunfeng Xinchuang
                                                                                       67,935,704.36                     Net assets
     Equity Investment Center (上海云锋新创股权投资中心)
     Other equity instrument investments - Shanghai JingYi Investment
                                                                                       73,616,359.91                     Net assets
     Center (上海经颐投资中心) (L.P.)
     Other equity instrument investments-Qianhai Equity Investment Fund
                                                                                      243,378,742.17                     Net assets
     (前海股权投资基金) (L.P.)
     Other equity instrument investments -PANTHEOND,L.P.                                   5,954,301.20                  Net assets
     Other equity instrument investments –Apricot Forest, Inc                        120,788,500.00                Income method
     Other equity instrument investments –Zhuhai China Resources Bank
                                                                                      158,400,000.00                 Market method
     Co., Ltd. (珠海华润银行股份有限公司)
     Other equity instrument investments - Yizun Biopharmaceutics
                                                                                       30,513,209.27                 Market method
     (Shanghai) Co., Ltd. (羿尊生物医药(上海) 有限公司) )
     Other equity instrument investments - Zhuhai Medpha Biotechnology
                                                                                       32,099,443.70         Recent financing price
     Co., Ltd. (珠海麦得发生物科技股份有限公司) ) )
     Other equity instrument investments- Beijing Luzhu Biotechnology
                                                                                       53,654,738.60         Recent financing price
     Co., Ltd. (北京绿竹生物技术股份有限公司)
     Other equity instruments investment- Xiangrong (Shanghai)
                                                                                       19,613,667.00         Recent financing price
     Biotechnology Co., Ltd. (享融(上海) 生物科技有限公司)


                                                                   272
     Joincare Pharmaceutical Group                                                                              Annual Report 2022


                                                                                Fair value as at
                                     Content                                                               Valuation techniques
                                                                                  2022.12.31
     Other equity instrument investments –GLOBAL HEALTH SCIENCE                    271,980,388.15                       Net assets
     Other equity instrument investments –SCC VENTURE VI 2018-
                                                                                        257,909.57                       Net assets
     B,L.P.
     Other equity instrument investments –Nextech V Oncology S.C.S.,
                                                                                     23,996,121.32                       Net assets
     SICAV-SIF
     Other equity instrument investments -Others                                     82,154,309.86                               Cost




X. Related party and related party transactions

1. Information of parent company

                                                                                        Shareholding ratio Voting right by
      Name of parent       Place of
                                               Business nature       Registered capital by parent company parent company
        company          registration
                                                                                               (%)              (%)
     Shenzhen                                    Investment and
     Baiyeyuan                         establishment of industry,
     Investment Co.,          Shenzhen domestic commerce, and             80,000,000.00            45.53                 45.53
     Ltd. (深圳市百业                        material supply and
     源投资有限公司)                                   marketing

     The ultimate controller of the Company is Zhu Baoguo (朱保国).

     (1) Registered capital of parent company and its changes

          Name of parent company                   2021.12.31            Increase           Decrease               2022.12.31
     Shenzhen Baiyeyuan Investment
     Co., Ltd. (深圳市百业源投资有限                80,000,000.00                   0.00             0.00               80,000,000.00
     公司)

     (2) Shares of the company held by the parent company and its changes

      Name of other related
                                     2021.12.31          Ratio      Increase        Decrease               2022.12.31         Ratio
             parties
     Shenzhen Baiyeyuan
     Investment Co., Ltd.
                                     895,653,653.00      46.95%          0.00      17,380,900.00       878,272,753.00            45.53%
     (深圳市百业源投资有
     限公司)
     On 20 September 2022, Shenzhen Baiyeyuan Investment Co., Ltd. (深圳市百业源投资有限公司) lent
     17,380,900 shares due to participating in the refinancing securities lending business, and the ownership of
     this part of the equity has not been transferred in the current period.

2. Subsidiaries of the Company

     Details of subsidiaries refer to Note VII. 1

3. Joint venture and associates of the Company

     Details of significant joint ventures or associates refer to Notes V.11 and VII. 2.

     Other joint ventures or associates entered into transactions with the Company during the period, or during
     the prior period with remaining closing balance were as follows:

               Name of joint ventures and associates                             Relationship with the Company
     Jiaozuo Jinguan Jiahua Electric Power Co., Ltd. (焦作金冠
                                                                                                                        Associates
     嘉华电力有限公司)


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     Joincare Pharmaceutical Group                                                                      Annual Report 2022


               Name of joint ventures and associates                          Relationship with the Company
     Guangdong Blue Treasure Pharmaceutical Co. Ltd. (广东蓝
                                                                                                                Associates
     宝制药有限公司)
     Novastage Pharmaceuticals (Shenzhen) , Ltd. (新领医药技
                                                                                                                Associates
     术(深圳) 有限公司)
     Shenzhen City Youbao Technology Co., Ltd. (深圳市有宝科
                                                                                                                Associates
     技有限公司)
     AbCyte Therapeutics Inc.                                                                                   Associates
     L&L Biopharma, Co. Ltd. (上海健信生物医药科技有限公
                                                                                                                Associates
     司)
     Zhuhai Sanmed Biotech Inc. (珠海圣美生物诊断技术有限
                                                                                                                Associates
     公司)
     Aetio Biotherapy Inc                                                                                       Associates
     Jiangsu Atom Bioscience and Pharmaceutical Co., Ltd. (江苏
                                                                                                                Associates
     新元素医药科技有限公司)
     Tianjin Tongrentang Group Co., Ltd. (天津同仁堂集团股份
                                                                                                                Associates
     有限公司)
     Infinite Intelligence Pharmaceutical Co. Ltd. (北京英飞智药
                                                                                                                Associates
     科技有限公司)
     Shenzhen Kangti Biomedical Technology Co., Ltd. (深圳康
                                                                                                                Associates
     体生物医药科技有限公司)
     Shanghai Sheo Pharmaceutical Technology Co., Ltd. (上海偕
                                                                                                                Associates
     怡医药科技有限公司)
     Zhuhai Sanmed Gene Diagnostics Ltd. (珠海市圣美基因检
                                                                                          Entity controlled by an associate
     测科技有限公司)
     Zhuhai Hengqin Weisheng Precision Medicine Technology
                                                                                          Entity controlled by an associate
     Co., Ltd. (珠海横琴维胜精准医学科技有限公司)

4. Other related parties of the Company

                    Name of other related parties                              Relationship with the Company
     Shenzhen Taitelixing Investment Development Co., Ltd. (深圳
                                                                  Subsidiaries of the company’s ultimate actual controller
     泰特力兴投资发展有限公司)
     Zhuozhou Jingnan Yongle Golf Club Co., Ltd. (涿州京南永乐
                                                                 A company controlled by the Company’s parent company
     高尔夫俱乐部有限公司)
     Shenzhen Healthy Deer Information Technology Co., Ltd. (深
                                                                          An associate of the Company’s parent company
     圳市健康阿鹿信息科技有限公司)
     Sichuan Healthy Deer Hospital Management Co., Ltd. and its      A subsidiary of an associate of the Company’s parent
     subsidiaries (四川健康阿鹿医院管理有限公司及其子公司)                                                         company
     Zhuhai Medpha Biotechnology Co., Ltd. (珠海麦得发生物科 The supervisor of Livzon Group works as director for t
     技股份有限公司)                                                                                              his entity
     Zhuhai Xianghetai Investment Management Partnership
     (Limited Partnership) (珠海祥和泰投资管理合伙企业(有限合           The executive of Livzon Group controls this entity
     伙) )
     Zhuhai Zhong Hui Yuan Investment Partnership (Limited
                                                                         The director of Livzon Group controls this entity
     Partnership) (珠海中汇源投资合伙企业(有限合伙)
     Zhuhai Liying Investment Management Partnership (Limited
                                                                         The director of Livzon Group controls this entity
     Partnership) (珠海丽英投资管理合伙企业(有限合伙) )
     Jiangsu One Winner Medical Technology Co., Ltd. (江苏一赢
                                                                         The director of Livzon Group controls this entity
     家医疗科技有限公司)
     Zhuhai Pu Xiaoying Enterprise Management Co., Ltd. (Zhuhai
                                                                 The close family member of the director of Livzon Group
     Pu Xiaoying Enterprise Management Co., Ltd. (珠海市蒲小英
                                                                                                         controls this entity
     企业管理有限公司))
     Directors, Supervisors and other senior management personnel                                 Key management personnel

5. Related party transactions

(1) Purchase or sale with related parties

                                                               274
     Joincare Pharmaceutical Group                                                                              Annual Report 2022


      ①Purchase of goods/receiving of services

                  Name of other related parties                  Nature of transaction      Current year          Prior year
     Guangdong Blue Treasure Pharmaceutical Co. Ltd. (广东
                                                                          Raw materials        2,917,946.91        2,786,053.10
     蓝宝制药有限公司)
     Zhuhai Sanmed Biotech Inc. (珠海圣美生物诊断技术有
                                                                         Finished goods                  0.00         28,558.55
     限公司)
     Sichuan Healthy Deer Hospital Management Co., Ltd. and
     its subsidiaries (四川健康阿鹿医院管理有限公司及其               Finished goods,
                                                                                                         0.00        887,872.67
                                                                   Business promotion
     子公司)
     Jiangsu One Winner Medical Technology Co., Ltd. (江苏
                                                                   Business promotion          3,160,667.40          408,427.00
     一赢家医疗科技有限公司)
     Zhuhai Sanmed Gene Diagnostics Ltd. (珠海市圣美基因
                                                                                Testing          137,358.49           14,377.36
     检测科技有限公司)
     L&L Biopharma, Co. Ltd. (上海健信生物医药科技有限                     Research and
                                                                                                         0.00        943,396.20
     公司)                                                                 development
     Shenzhen City Youbao Technology Co., Ltd. (深圳市有
                                                                   Business promotion          2,083,948.00        1,062,850.00
     宝科技有限公司)
     Zhuozhou Jingnan Yongle Golf Club Co., Ltd. (涿州京南
                                                                        Member services                  0.00         84,037.00
     永乐高尔夫俱乐部有限公司)
     Infinite Intelligence Pharmaceutical Co. Ltd. (北京英飞智             Research and
                                                                                                 339,805.83          148,514.85
     药科技有限公司)                                                       development
     Zhuhai Pu Xiaoying Enterprise Management Co., Ltd. (珠
                                                                        Modern services          249,975.00                0.00
     海市蒲小英企业管理有限公司)
     Shanghai Sheo Pharmaceutical Technology Co., Ltd. (上                 Research and
                                                                                              18,867,924.60                0.00
     海偕怡医药科技有限公司)                                               development
     Feellife Health Inc. (深圳来福士雾化医学有限公司)                        Nebulizer          902,115.48                0.00
     Jiaozuo Jinguan Jiahua Electric Power Co., Ltd. (焦作金
                                                                     Electricity, Steam      268,666,999.03      212,585,953.81
     冠嘉华电力有限公司)
                              Total                                                          297,326,740.74      218,950,040.54

     ②Sales of goods/rendering of services

                   Name of related parties                     Nature of transaction        Current year           Prior year
     Guangdong Blue Treasure Pharmaceutical Co. Ltd. (广            Finished Products,
                                                                                               35,703,972.73        63,972,886.45
     东蓝宝制药有限公司)                                       Hydropower and Power
     Zhuhai Sanmed Biotech Inc. (珠海圣美生物诊断技术               Finished Products,
                                                               Hydropower, Power and             1,435,666.13         577,453.14
     有限公司)                                                                  others
     Sichuan Healthy Deer Hospital Management Co., Ltd.
     and its subsidiaries (四川健康阿鹿医院管理有限公司              Finished Products           3,036,532.62        4,951,551.99
     及其子公司)
     Zhuhai Sanmed Gene Diagnostics Ltd. (珠海市圣美基              Finished Products,
                                                               Hydropower, Power and              592,356.49          667,998.89
     因检测科技有限公司)                                                        others
     Shanghai Sheo Pharmaceutical Technology Co., Ltd.                   Research and
                                                                                                 3,960,000.00                  0.00
     (上海偕怡医药科技有限公司)                                           development
                             Total                                                             44,728,527.97        70,169,890.47

(2) Rental with related party

                                                     Type of assets        Rental income in current        Rental income in prior
                    Name of lessee
                                                        leased                       year                           year
      Zhuhai Sanmed Biotech Inc. (珠海圣美生
                                                           Buildings                      2,226,299.00                 2,226,299.00
      物诊断技术有限公司)
      Zhuhai Sanmed Gene Diagnostics Ltd. (珠
                                                           Buildings                       240,000.00                    240,000.00
      海市圣美基因检测科技有限公司)


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     Joincare Pharmaceutical Group                                                               Annual Report 2022


                                                 Type of assets    Rental income in current   Rental income in prior
                   Name of lessee
                                                    leased                   year                      year
      Shenzhen Baiyeyuan Investment Co., Ltd.
                                                       Buildings                  18,891.76                 18,891.76
      (深圳市百业源投资有限公司)
      Novastage Pharmaceuticals (Shenzhen) ,        Buildings &
                                                                                 468,302.76                315,457.80
      Ltd. (新领医药技术(深圳) 有限公司)             Equipment
      Shenzhen Taitelixing Investment
      Development Co., Ltd. (深圳泰特力兴投            Buildings                  18,720.00                 18,720.00
      资发展有限公司)
      Shenzhen Healthy Deer Information
      Technology Co., Ltd. (深圳市健康阿鹿信           Buildings                  17,174.32                 17,174.32
      息科技有限公司)
      Shenzhen City Youbao Technology Co.,
                                                       Buildings                  17,174.32                 17,174.32
      Ltd. (深圳市有宝科技有限公司)
                        Total                                                  3,006,562.16              2,853,717.20

(3) Guarantee with related parties

     ① In order to ensure the stable development of production and operation of Jinguan Electric Power, the
     Company and its controlling subsidiary Jiaozuo Joincare jointly provided a revolving guarantee facility with
     balance of no more than RMB350 million (inclusive) for Jinguan Electric Power (specific guarantors shall be
     specified in the guarantee contracts) according to “the Resolution on Providing Loan Guarantee for Jinguan
     Electric Power by the Company and Its Controlling Subsidiary Jiaozuo Joincare” considered and approved at
     the First Extraordinary General Meeting of the Company on 6 July 2016, with the guarantee period starting
     from the date when the resolution was considered and approved to 31 December 2019. Pursuant to “the
     Resolution on Providing Loan Guarantee for Jinguan Electric Power by the Company and Its Controlling
     Subsidiary Jiaozuo Joincare” considered and approved at the 2017 Annual General Meeting of the Company
     on 22 May 2018, the Company and its controlling subsidiary Jiaozuo Joincare jointly provided a revolving
     guarantee facility with balance of no more than RMB350 million (inclusive) for Jinguan Electric Power
     (specific guarantors shall be specified in the guarantee contracts), with the guarantee period starting from the
     date when the resolution was considered and approved to 31 December 2022. In order to ensure the stable
     development of production and operation of Jinguan Electric Power, the revolving guarantee facility with
     balance of no more than RMB350 million (inclusive) for Jinguan Electric Power (specific guarantors shall be
     specified in the guarantee contracts) considered and approved at the 2017 General Meeting of the Company
     was changed to the revolving guarantee facility with balance of no more than RMB450 million (inclusive) on
     10 May 2019 due to the actual business needs of Jinguan Electric Power, with the guarantee period starting
     from the date when the resolution was considered and approved to 31 December 2022. On 18 May 2022, the
     "Proposal on the Company and its subsidiary Jiaozuo Joincare in Providing Loan Guarantee for Jinguan
     Electric Power" was reviewed and approved by the Company's 2021 annual general meeting, the Company
     and its subsidiary Jiaozuo Joincare jointly provided a guarantee for Jinguan Electric Power on its revolving
     loans facility with a balance of not more than RMB450 million (including RMB450 million) (the specific
     guarantor will be specified in each guarantee contract), and the term is from the date of approval of this
     guarantee proposal at the Company’s annual general meeting to 31 December 2025.

     As at 31 December 2022, the Company provided Jinguan Electric Power with guarantees for loans of
     RMB378.40 million; of which RMB222 million in Shenzhen Branch of China Everbright Bank, RMB90
     million in Shenzhen Branch of Zheshang Bank, RMB46.40 million in Shenzhen Branch of Nanyang
     Commercial Bank and RMB20 million in Jiaozuo Branch of China CITIC Bank.

     In order to ensure the safety of secured loans, Jinguan Electric Power provided counter guarantees for the
     said guarantees provided by the Company and its subsidiary, Jiaozuo Joincare, based on its owned assets,
     and undertook that it would unconditionally provide mutual guarantees for the Company or its controlling
     subsidiary designated with total facility of no more than RMB450 million (inclusive) whenever the Company
     deemed necessary.

     ② Another shareholder of Livzon MABPharm Inc. (珠海市丽珠单抗生物技术有限公司) – the Company
     has issued a "Counter Guarantee Commitment", promising that it will share the joint and several guarantee
     liability to the extent of 33.07% of the scope of guarantee responsibility in relation to the guarantee provided


                                                           276
     Joincare Pharmaceutical Group                                                                    Annual Report 2022


     to Livzon MABPharm Inc. (珠海市丽珠单抗生物技术有限公司), and the counter guarantee period will
     expire on the date when the Company's guarantee responsibility expiry.

     ③ Zhuhai Zhong Hui Yuan Investment Partnership (Limited Partnership) (珠海中汇源投资合伙企业(有限
     合伙), being another shareholder of Livzon Group Xinbeijiang Pharmaceutical Manufacturing Inc. (丽珠集
     团新北江制药股份有限公司) has issued a "Counter Guarantee Commitment", promising that it will share
     the joint and several guarantee liability to the extent of 8.44% of the scope of guarantee responsibility incurred
     by Livzon Group in relation to the guarantee provided to Livzon MABPharm Inc. (珠海市丽珠单抗生物技
     术有限公司), and the counter guarantee period will expire on the date when Livzon Group's guarantee
     responsibility expiry.

(4) Asset transfer and debt restructuring between related parties

     None.

(5) Remuneration of key management personnel

                                                                                               Unit: RMB ten thousand

     For the year ended 31 December 2022

                        Director/
                                     Wages and       Social          Housing              Severance
                       Supervisor                                               Bonus               Others       Total
                                     allowances     security          fund                   pay
                       Allowance
     Directors:
     Zhu Baoguo
                            325.00           0.00       6.44             2.66      0.00        0.00      0.00     334.09
     (朱保国)
     Liu Guangxia
                            325.00         18.48        1.85             2.66      0.00        0.00      0.00     347.98
     (刘广霞)
     Yu Xiong (俞
                              0.00        260.00        0.00             0.00    100.00        0.00      0.00     360.00
     雄)
     Qiu Qingfeng
                              0.00        135.00        7.27             2.66     80.00        0.00      0.00     224.93
     (邱庆丰)
     Lin Nanqi (林
                              0.00        135.00        7.27             2.66     80.00        0.00      0.00     224.93
     楠棋)
     Cui Liguo (崔
                             11.54           0.00       0.00             0.00      0.00        0.00      0.00      11.54
     利国)
     Huo Jing (霍
                             11.54           0.00       0.00             0.00      0.00        0.00      0.00      11.54
     静)
     Qin Yezhi (覃
                             11.54           0.00       0.00             0.00      0.00        0.00      0.00      11.54
     业志)
     Peng Juan (彭
                             11.54           0.00       0.00             0.00      0.00        0.00      0.00      11.54
     娟)
     Supervisors:
     Yu Xiaoyun (余
                              4.80         38.31        6.82             2.25     17.95        0.00      0.00      70.13
     孝云)
     Peng Jinhua (彭
                              4.80           0.00       0.00             0.00      0.00        0.00      0.00       4.80
     金花)
     Xing Zhiwei
                              2.97         64.00        6.82             2.09     93.00        0.00      0.00     168.88
     (幸志伟)
     Xie Youguo (谢
                              1.83         36.92        0.00             0.00      0.00        0.00      0.00      38.75
     友国)
     Other senior
     management:
     Zhao Fenguang
                              0.00        135.00        7.27             2.66     45.00        0.00      0.00     189.93
     (赵凤光)
          Total             710.57        822.71       43.75            17.61    415.95        0.00      0.00   2,010.58



                                                               277
     Joincare Pharmaceutical Group                                                                     Annual Report 2022


     Note: Mr. Zhu Baoguo (朱保国) serves as the chairman of Livzon Group, a controlled subsidiary of the
     Company; and Mr. Yu Xiong (俞雄) and Mr. Qiu Qingfeng (邱庆丰) serve as non-executive directors of
     Livzon Group. Xie Youguo (谢友国) has resigned. The remuneration presented in above does not include
     the portion paid by Livzon Group.


     For the year ended 31 December 2021

                        Director/
                                       Wages and      Social          Housing              Severance
                       Supervisor                                                Bonus               Others       Total
                                       allowances    security          fund                   pay
                       Allowance
     Directors:
     Zhu Baoguo
                            330.94            0.00       6.22             2.40      0.00        0.00      0.00     339.56
     (朱保国)
     Liu Guangxia
                            330.94           17.91       8.01             2.40      0.00        0.00      0.00     359.27
     (刘广霞)
     Yu Xiong
                              0.00          240.00       0.00             0.00     95.00        0.00      0.00     335.00
     (俞雄)
     Qiu Qingfeng
                              0.00          135.00       6.22             2.40     30.00        0.00      0.00     173.62
     (邱庆丰)
     Lin Nanqi
                              0.00          135.00       6.22             2.40     30.00        0.00      0.00     173.62
     (林楠棋)
     Cui Liguo
                             10.00            0.00       0.00             0.00      0.00        0.00      0.00      10.00
     (崔利国)
     Huo Jing
                             10.00            0.00       0.00             0.00      0.00        0.00      0.00      10.00
     (霍静)
     Qin Yezhi
                             10.00            0.00       0.00             0.00      0.00        0.00      0.00      10.00
     (覃业志)
     Peng Juan
                              3.60            0.00       0.00             0.00      0.00        0.00      0.00       3.60
     (彭娟)
     Supervisors:
     Yu Xiaoyun (余
                              4.00           38.16       6.01             2.18     17.95        0.00      0.00      68.29
     孝云)
     Peng Jinhua (彭
                              4.00           32.73       0.00             1.36      0.00        0.00      0.00      38.09
     金花)
     Xie Youguo
                              4.00           36.35       0.00             1.17      2.86        0.00      0.00      44.38
     (谢友国)
     Other senior
     management:
     Zhao Fenguang
                              0.00          135.00       6.22             2.40     25.00        0.00      0.00     168.62
     (赵凤光)
          Total             707.48          770.14      38.88            16.74    200.81        0.00      0.00   1,734.05


     Note: Mr. Zhu Baoguo (朱保国) serves as the chairman of Livzon Group, a controlled subsidiary of the
     Company; and Mr. Yu Xiong (俞雄) and Mr. Qiu Qingfeng (邱庆丰) serve as non-executive directors of
     Livzon Group. The remuneration presented in above does not include the portion paid by Livzon Group.

(6) Other related party transactions

     None.

6. Receivables and payables with related party

(1) Receivable from related parties




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     Joincare Pharmaceutical Group                                                                                  Annual Report 2022


                                                                               2022.12.31                       2021.12.31
        Item                       Related party                                                                           Provision
                                                                                        Provision for
                                                                    Book balance                      Book balance          for bad
                                                                                         bad debts
                                                                                                                             debts
  Notes             Guangdong Blue Treasure Pharmaceutical Co.
                                                                      3,893,820.00               0.00      5,492,960.00            0.00
  receivable        Ltd. (广东蓝宝制药有限公司)
  Accounts          Guangdong Blue Treasure Pharmaceutical Co.
                                                                      4,781,500.00          47,336.85     18,889,500.00    490,875.00
  receivable        Ltd. (广东蓝宝制药有限公司)
  Accounts          Zhuhai Sanmed Gene Diagnostics Ltd. (珠海
                                                                          85,731.98           840.17         224,023.83       8,578.07
  receivable        市圣美基因检测科技有限公司)
                    Sichuan Healthy Deer Hospital Management
  Accounts
                    Co., Ltd. and its subsidiaries (四川健康阿鹿         497,828.30       103,325.48         337,395.02      48,933.97
  receivable
                    医院管理有限公司及其子公司)
                    Zhuhai Sanmed Biotech Inc. (珠海圣美生物
  Prepayments                                                            211,200.00              0.00        211,200.00            0.00
                    诊断技术有限公司)
                    Shenzhen City Youbao Technology Co., Ltd.
  Prepayments                                                            188,100.00              0.00        154,500.00            0.00
                    (深圳市有宝科技有限公司)
                    Jiaozuo Jinguan Jiahua Electric Power Co.,
  Prepayments                                                        75,724,913.57               0.00      8,240,517.56
                    Ltd. (焦作金冠嘉华电力有限公司)
  Other             Zhongshan Renhe Health Products Co., Ltd.
                                                                         469,895.78       469,895.78         469,895.78    469,895.78
  receivables       (中山市仁和保健品有限公司)
  Other             Shenzhen Jiekang Health Care Co., Ltd. (深圳                                                          18,577,246.6
                                                                                 0.00            0.00     18,577,246.63
  receivables       市捷康保健有限公司 )                                                                                             3
                    Shenzhen Healthy Deer Information
  Other
                    Technology Co., Ltd. (深圳市健康阿鹿信息               4,680.00            74.38           4,680.00         74.38
  receivables
                    科技有限公司)
  Other             Guangdong Blue Treasure Pharmaceutical Co.
                                                                         607,484.29          6,925.32      1,271,496.55      21,233.99
  receivables       Ltd. (广东蓝宝制药有限公司)
  Other             Zhuhai Sanmed Gene Diagnostics Ltd. (珠海
                                                                          15,795.00           170.59           5,265.00         87.93
  receivables       市圣美基因检测科技有限公司)

(2) Payables to related party

            Item                                 Related party                                  2022.12.31            2021.12.31
                          Guangdong Blue Treasure Pharmaceutical Co. Ltd. (广东蓝
   Notes payable                                                                                             0.00          379,960.00
                          宝制药有限公司)
                          Sichuan Healthy Deer Hospital Management Co., Ltd. and its
   Contract liabilities                                                                                 12,011.72                  0.00
                          subsidiaries (四川健康阿鹿医院管理有限公司及其子公司)
                          Sichuan Healthy Deer Hospital Management Co., Ltd. and its
   Other payables                                                                                        8,936.17            8,936.17
                          subsidiaries (四川健康阿鹿医院管理有限公司及其子公司)



XI. Share-based payments

1. Information about share-based payments

     (1) The Company
                                                     Item                                                           Related content
       Total amount of equity instruments granted during the year (shares)                                                   49,450,000
       Total amount of equity instruments exercised during the year (shares)                                                  8,596,134
       Total amount of equity instruments forfeited during the year (shares)                                                       26,000
       Range of exercise price and residual life of outstanding share options at the end of the
                                                                                                                                      Note
       year
       Range of exercise price and residual life of outstanding other equity instruments at the end
                                                                                                                                       —
       of the year

     Note: Share Option


                                                                   279
Joincare Pharmaceutical Group                                                                             Annual Report 2022


① On 29 August 2022, the Company held the third extraordinary general meeting of shareholders in 2022,
and reviewed and approved the "Proposal on the Company's 2022 Stock Option Incentive Plan (Draft) and its
Summary", Proposal on the Company's 2022 Stock Option Incentive Plan Implementation Appraisal
Management Measures" and "Proposal on Requesting the Company's Shareholders' Meeting to Authorize the
Board of Directors to Handle Matters Related to Shares Incentive". The Company held the 16th meeting of
the eighth board of directors on 5 September 2022, and reviewed and passed the "Proposal on First Time
Granting Stock Options to Incentive Participants". With 5 September 2022 as the grant date, 49.45 million
stock options were granted to 423 incentive participants at a price of RMB11.24 per share. The date of
completion and effective date of registration of stock options granted is 16 September 2022.

The exercise period of the options granted this time and the exercise time schedule for each period are shown
in the following table:

    Vesting period                                          Vesting date                                   Vesting ratio
                            From the first trading day 12 months after the first grant date to the last
First vesting period                                                                                                 40%
                            trading day within 24 months from the first grant date
                            From the first trading day 24 months after the first grant date to the last
Second vesting period                                                                                                30%
                            trading day within 36 months from the first grant date
                            From the first trading day 36 months after the first grant date to the last
Third vesting period                                                                                                 30%
                            trading day within 48 months from the first grant date

Company-level performance appraisal requirements: The stock options granted by this incentive plan are
subject to annual performance appraisal and vesting. To achieve the performance appraisal target as the vesting
condition for incentive participants, the annual performance appraisal targets for the first-time grant are shown
in the table below:

     Vesting period                                         Performance appraisal targets
                            Based on the net profit in 2021, the compound growth rate of net profit in 2022 shall not be
First vesting period
                            less than 15%;
                            Based on the net profit in 2021, the compound growth rate of net profit in 2023 shall not be
Second vesting period
                            less than 15%;
                            Based on the net profit in 2021, the compound growth rate of net profit in 2024 shall not be
Third vesting period
                            less than 15%.

The calculation of the above "net profit" and "net profit growth rate" indicators is based on the net profit
attributable to shareholders of listed company after deducting non-recurring gains and losses, and excluding
the impact of share-based payments in this incentive plan. If the Company fails to meet the above-mentioned
performance appraisal targets, all incentive participants whose stock options are exercisable in the year
corresponding to the appraisal shall not be exercised and shall be canceled by the Company.

② On 13 December 2018, the Company held the third extraordinary general meeting of shareholders in 2018,
and reviewed and approved the "Proposal on the Company's 2018 Stock Option Incentive Plan (Draft) and its
summary". The stock options granted for the first time was granted on 21 December 2018, with a grant price
of RMB8.21 per share, and would expire on 20 December 2022. The reserved stock options were granted on
23 September 2019, with a grant price of RMB10.47 per share, and would expire on 22 September 2022.

(2) The Company’s subsidiary, Livzon Group

 Total amount of equity instruments granted during the year (shares)                                              17,973,500
 Total amount of equity instruments exercised during the year (shares)                                             1,091,966
 Total amount of equity instruments forfeited during the year (shares)                                             4,905,012
 Range of exercise price and residual life of outstanding share options at the end of the year                        Note 1
 Range of exercise price and residual life of outstanding other equity instruments at the end
                                                                                                                      Note 2
 of the year

Note 1:Share Option

① On 14 October 2022, Livzon Group’s 2022 Second Extraordinary Shareholders’ Meeting, 2022 Second

                                                              280
Joincare Pharmaceutical Group                                                                            Annual Report 2022


A-Share Class Shareholders’ Meeting and 2022 H-Share Class Shareholders’ Meeting reviewed and approved
the “Proposal on the Company's 2022 Stock Option Incentive Plan (Revised Draft) and Its Summary",
"Proposal on the company's 2022 Stock Option Incentive Plan Implementation Appraisal Management
Measures", "Proposal on submitting to the company's general meeting of shareholders to authorize the board
of directors to handle matters related to the 2022 stock options incentive plan". On 7 November 2022, the
39th meeting of the 10th Board of Directors of Livzon Group reviewed and approved the "Proposal on Matters
Related to the First Time Grant of the 2022 Stock Option Incentive Plan". With 7 November 2022 as the grant
date, 17,973,500 stock options were granted to 1,026 incentive participants at a price of RMB31.31 per A
share. The date of completion and effective date of registration of stock options granted is 23 November 2022.

The exercise period of the options granted this time and the exercise time schedule for each period are shown
in the following table:

    Vesting period                                         Vesting date                                     Vesting ratio
First vesting period of    From the first trading day 12 months after the completion of the first time
stock options granted      grant registration to the last trading day within 24 months from the                       40%
for the first time         completion of the first time grant registration
Second vesting period      From the first trading day 24 months after the completion of the first time
of stock options granted   grant registration to the last trading day within 36 months from the                       30%
for the first time         completion of the first time grant registration
Third vesting period of    From the first trading day 36 months after the completion of the first time
stock options granted      grant registration to the last trading day within 48 months from the                       30%
for the first time         completion of the first time grant registration

Livzon Group performance appraisal requirements: The stock options granted by this incentive plan are
subject to annual performance appraisal and vesting during the 3 fiscal years of the vesting period. To achieve
the performance appraisal target as the vesting condition for incentive participants, the annual performance
appraisal targets for the first-time grant are shown in the table below:

            Vesting period                                          Performance appraisal targets
First vesting period of stock options      Based on the net profit in 2021, the compound growth rate of net profit in 2022
granted for the first time                 shall not be less than 15%;
Second vesting period of stock options     Based on the net profit in 2021, the compound growth rate of net profit in 2023
granted for the first time                 shall not be less than 15%;
Third vesting period of stock options      Based on the net profit in 2021, the compound growth rate of net profit in 2024
granted for the first time                 shall not be less than 15%.

The calculation of the above "net profit" and "net profit compound growth rate" indicators is based on the net
profit attributable to shareholders of listed company after deducting non-recurring gains and losses, and
excluding the impact of share-based payments in this incentive plan. If the Company fails to meet the above-
mentioned performance appraisal targets, all incentive participants whose stock options are exercisable in the
year corresponding to the appraisal shall not be exercised and shall be canceled by the Company.

② On 5 September 2018, Livzon Group’s 2018 Third Extraordinary Shareholders’ Meeting, the 2018 Third
A-Share Class Shareholders’ Meeting and the 2018 H-Share Class Shareholders’ Meeting reviewed and
approved the “Proposal on the Company's 2018 Stock Option Incentive Plan (Revised Draft) and its
Summary”. The stock options granted for the first time was granted on 11 September 2018, with a grant price
of RMB47.01 per share, and would expire on 23 September 2022. The reserved stock options were granted
on 28 August 2019, with a grant price of RMB28.87 per A-share, and would expire on 26 October 2022.

Note 2: Other equity incentive

Pursuant to “ the Resolution on the Disposal of Certain Equity of a Holding Subsidiary and Connected
Transaction” considered and approved at the 34th Meeting of the 9th Session of the Board of Livzon Group
on 8 November 2019, it was agreed that 9.5% equity interests (totally 8,382,100 shares) in Zhuhai Livzon
Diagnostics Inc. (珠海丽珠试剂股份有限公司) held by Livzon Group shall be transferred to Zhuhai Liying
Investment Management Partnership (Limited Partnership) (珠海丽英 投资管理合伙企业(有限合伙)) at
the consideration of RMB21,122,892. Pursuant to the Assets Appraisal Report on the Valuation of the
Shareholders'. According to “Assets evaluation report of all shareholders' equity value project of Zhuhai

                                                             281
     Joincare Pharmaceutical Group                                                              Annual Report 2022


     Livzon Diagnostics Inc. (珠海丽珠试剂股份有限公司) involved in the proposed transfer of equity by Livzon
     Pharmaceutical Group Co., Ltd.”. (Huaya Zhengxin Appraisal Report [2019] No. A02-0011), the valuation of
     all shareholders’ equity of Zhuhai Livzon Diagnostics Inc. as at 30 June 2019 was RMB647.3075 million, and
     the above equity transfer price was lower than its fair value, therefore it constitutes a share-based payment.
     The total share-based payment of the transaction is RMB40.4017 million, which should be amortized within
     5 years according to the partnership agreement and share incentive expenses were recognised due to the share-
     based payment as a result of the change in the shareholding of the shareholders of Zhuhai Liying Investment
     Management Partnership (Limited Partnership).

     Pursuant to “the Resolution on the Implementation of Employee Equity Incentive Scheme by a Holding
     Subsidiary” considered and approved at the 34th Meeting of the 9th Session of the Board of Livzon Group
     on 8 November 2019, the total number of shares of new issuance by Zhuhai Livzon Diagnostics Inc. for
     implementation of employee equity incentive scheme shall not be more than 4,643,839 shares, and the
     scheme participants shall contribute a total of RMB11,702,474.28 to directly subscribe for the above shares
     or indirectly subscribe for the such shares through the holding of the limited partnership shares of the
     employee shareholding platform. In December 2019, pursuant to the Capital Increase Agreement of Zhuhai
     Livzon Diagnostics Inc., the total shares of Zhuhai Livzon Diagnostics Inc. increased from 88,232,932 shares
     to 92,876,771 shares with par value of RMB1 per share. The increased number of shares were subscribed for
     by Zhuhai Haoxun Enterprise Management Consulting Partnership (Limited Partnership) (珠海豪汛企业管
     理咨询合伙企业(有限合伙)), Zhuhai Yichen Enterprise Management Consulting Partnership (Limited
     Partnership) (珠海熠臣企业管理咨询合伙企业(有限合伙)) and Zhuhai Qijing Enterprise Management
     Consulting Partnership (Limited Partnership) (海启靖企业管理咨询合伙企业(有限合伙)) at the
     consideration of RMB11,702,474. The subscription price is lower than the fair value, therefore it constitutes
     a share-based payment. The total share-based payment of the transaction is RMB20,709,000, which should
     be amortized within 5 years according to the Partnership Agreement, and share incentive expenses were
     recognized due to the share-based payment as a result of the change in the shares/shareholding of the
     shareholders or employee stock ownership platform of Zhuhai Livzon Diagnostics Inc.

     On 31 August 2021, the general meeting of Livzon Bio considered and approved the Equity Incentive Scheme
     of Zhuhai Livzon Biotechnology Co., Ltd. (珠海市麗珠生物醫藥科技有限公司), granting 66,666,667
     restricted shares of Livzon Biologics to incentive participants, among which 42 million shares were granted
     in the first batch and 24,666,667 shares were reserved. Incentive participants indirectly subscribed for the
     above shares through the holding of the limited partnership shares of the employee shareholding platform.
     The subscription price is lower than the fair value, therefore it constitutes a share-based payment. The total
     share-based payment of the transaction is RMB33.6 million, which should be amortized during the lock-up
     period according to the Equity Incentive Scheme of LivzonBio and the Grant Agreement and RMB16.24
     million was amortized in the 6-month period ended 30 June 2022.

2. Equity-settled share-based payments

     Method in determining the fair value of equity instruments at the date
                                                                                Black-Scholes Model, market price
     of grant
     Basis in determining the quantity of exercisable equity instruments                                      —
     Reason for significant difference of estimation between current year
                                                                                                            None
     and prior year
     Accumulated amount recorded in capital reserve for equity-settled
                                                                                                  194,032,737.35
     share-based payments
     Total expenses recognized for equity-settled share-based payments in
                                                                                                   57,076,979.08
     the year

3. Information on cash-settled share-based payments

     None.

XII. Commitments and contingencies

1. Significant commitments



                                                                  282
      Joincare Pharmaceutical Group                                                               Annual Report 2022


(1) Capital commitments

        Capital commitments entered into but not recognized in the
                                                                       Closing balance           Beginning balance
                         financial statements
        Commitments in relation to acquisition of long-term assets           455,161,816.72            582,336,168.87
        Commitments in relation to external investment                        12,000,000.00              8,000,000.00
        Commitments in relation to research and development                              0.00          309,313,880.64
       expenditures

(2) Other commitments

      None.

(3) Performance of previous commitments

      The Company has duly performed the capital expenditure commitments and the operating lease commitments
      and the other commitments as at 31 December 2022.

2. Contingencies

      As at 31 December 2022, there was no other significant contingency required to be disclosed by the Company.

XIII. Event after balance sheet date

1. Profit distribution

      On 7 April 2023, the twenty-third meeting of the eighth Board of Directors of the Company passed the 2022
      profit distribution plan. Based on the Company's total share capital deducted by the repurchased shares held
      in the Company's special securities account on the registration date determined by the implementation of the
      Company's 2022 annual profit distribution plan, a cash bonus of RMB1.80 (tax included) for every 10 shares
      will be distributed to all shareholders.

      The above profit distribution plan needs to be submitted to the company's 2023 annual general meeting of
      shareholders for consideration and approval.

      As of 7 April 2023, the Company has no other events that needed to be disclosed after the balance sheet date.

XIV. Other significant events

1. Leases

      The Company had adopted a simplified approach for short-term leases and leases of low value assets and did
      not recognize right-of-use assets and lease liabilities. The expense of short-term leases, leases of low value
      assets and variable lease payments not included in the measurement of lease liabilities are included in the
      expenses in the current period as follows:

                                           Item                                                 2022
      Short-term leases                                                                                2,583,258.77

      As of the balance sheet date, except for the above matters, the Company does not have other important matter
      to be disclosed.



XV. Notes to the significant financial statements item of the Parent Company

1. Notes receivable



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        Joincare Pharmaceutical Group                                                                                                             Annual Report 2022


                                                     2022.12.31                                                                2021.12.31
          Category                                    Provision                                                                Provision
                                                                              Carrying                                                                   Carrying
                              Book balance             for bad                                       Book balance               for bad
                                                                              amount                                                                     amount
                                                        debts                                                                    debts
        Bank
        acceptance            249,617,024.89                   0.00        249,617,024.89            374,296,302.21                       0.00      374,296,302.21
        bills
        Commercial
        acceptance                         0.00                0.00                        0.00                    0.00                   0.00                    0.00
        bills
              Total           249,617,024.89                   0.00        249,617,024.89            374,296,302.21                       0.00      374,296,302.21

(1) Notes receivable pledged at year end

                                    Category                                                            Amount pledged at year end
        Bank acceptance bills                                                                                                                     196,148,535.27

(2) Bills endorsed or discounted to other parties but not yet expired at balance sheet date

                                                                         Amount derecognized at year                     Amount not derecognized at year
                              Category
                                                                                    end                                               end
        Bank acceptance bills not yet mature but
                                                                                                287,052,316.14                                                        --
        already endorsed
        Bank acceptance bills not yet mature but
                                                                                                  81,834,471.01                                                       --
        already discounted
                               Total                                                            368,886,787.15

(3) There was no bills transferred into account receivables for non-performance by the issuer at balance sheet date
     of the period.
(4) Disclosure by method of provision for bad debts
                                                            2022.12.31                                                               2021.12.31

                                                                                                                                   Provision for bad
                                    Book balance            Provision for bad debts                          Book balance
          Category                                                                                                                       debts
                                                                                          Carrying                                           Expecte         Carrying
                                                                           Expected        value                                                             value
                                                                                                                                             d credit
                                Amount          Ratio (%)    Amount        credit loss                    Amount         Ratio (%) Amount
                                                                                                                                             loss rate
                                                                            rate (%)
                                                                                                                                               (%)
 Provision for bad debts on
 individual item
 Provision for bad debts on
                               249,617,024.89      100.00         0.00           0.00    249,617,024.89 374,296,302.21      100.00        0.00     0.00    374,296,302.21
 portfolio basis

 Including:

   Bank acceptance bills       249,617,024.89      100.00         0.00           0.00    249,617,024.89 374,296,302.21      100.00        0.00     0.00    374,296,302.21

              Total            249,617,024.89      100.00         0.00           0.00    249,617,024.89 374,296,302.21      100.00        0.00     0.00    374,296,302.21


(5) There was no accrual, recovery or reversal of bad debt provision during the period

(6) There was no actual write-off of notes receivable in the period

2. Accounts receivable

(1) Disclosure by ageing

                                    Ageing                                                      2022.12.31                                 2021.12.31
     Within one year                                                                                 290,962,991.84                               538,967,095.90
     1 to 2 years (inclusive of 2 years)                                                               2,684,445.48                                 1,410,787.21
     2 to 3 years (inclusive of 3 years)                                                               1,178,173.47                                      733,293.23


                                                                                          284
      Joincare Pharmaceutical Group                                                                                                    Annual Report 2022


                                    Ageing                                           2022.12.31                                2021.12.31
    3 to 4 years (inclusive of 4 years)                                                           641,804.42                               388,712.49
    4 to 5 years (inclusive of 5 years)                                                           388,712.49                               360,879.34
    Over 5 years                                                                                7,754,530.87                             7,723,623.65
                                Subtotal                                                   303,610,658.57                             549,584,391.82
    Less: Provision for bad debts                                                           11,979,800.83                               14,041,321.58
                                    Total                                                  291,630,857.74                             535,543,070.24


(2) Disclosure by method of provision for bad debts

                                                2022.12.31                                                             2021.12.31

                      Book balance           Provision for bad debts                            Book balance         Provision for bad debts
   Category
                                                                            Carrying                                                               Carrying
                                                           Expected                                                                Expected
                                    Ratio                                   value                            Ratio                                  value
                      Amount                  Amount       credit loss                      Amount                    Amount       credit loss
                                    (%)                                                                      (%)
                                                           rate (%)                                                                rate (%)
 Provision for
 bad debts on         771,300.68     0.25     771,300.68       100.00             0.00          771,300.68    0.14    771,300.68       100.00             0.00
 individual item
 Including:
    Receivables
 from domestic       771,300.68 0.25     771,300.68            100.00             0.00          771,300.68    0.14    771,300.68       100.00             0.00
 customers
    Receivables
 from overseas             0.00 0.00           0.00               0.00            0.00                0.00    0.00          0.00          0.00            0.00
 customers
 Provision for
 bad debts on    302,839,357.89 99.75 11,208,500.15               3.70 291,630,857.74 548,813,091.14 99.86 13,270,020.90                  2.42 535,543,070.24
 portfolio basis
 Including:
    Receivables
 from domestic 302,839,357.89 99.75 11,208,500.15                 3.70 291,630,857.74 548,813,091.14 99.86 13,270,020.90                  2.42 535,543,070.24
 customers
    Receivables
 from overseas           0.00 0.00           0.00                 0.00            0.00                0.00    0.00          0.00          0.00            0.00
 customers
     Total         303,610,658.57     100 11,979,800.83           3.95 291,630,857.74 549,584,391.82           100 14,041,321.58          2.55 535,543,070.24

      Provision for bad debts on individual item:

                                                                                                2022.12.31
                   Name                                                  Provision for bad           Expected credit
                                              Book balance                                                                         Reason of provision
                                                                               debts                  loss rate (%)
                                                                                                                                         Not expected to be
   Purchase of goods                                 771,300.68                 771,300.68                       100.00
                                                                                                                                               recoverable
                   Total                             771,300.68                 771,300.68                       100.00

      Provision for bad debts on portfolio basis:

      Provision for bad debts on portfolio basis:Receivables from domestic customers

                                                       2022.12.31                                                       2021.12.31
                                                                              Expected                                                           Expected
                                     Accounts              Provision for                             Accounts             Provision for
                                                                              credit loss                                                        credit loss
                                     receivable             bad debts                                receivable            bad debts
                                                                               rate (%)                                                           rate (%)
  Within one year                    290,962,991.84          2,721,949.54                0.94        538,967,095.90           5,259,670.96               0.98
  1 to 2 years (inclusive
                                       2,684,445.48            282,436.48            10.52             1,410,787.21             150,539.36             10.67
  of 2 years)


                                                                               285
      Joincare Pharmaceutical Group                                                                       Annual Report 2022


  2 to 3 years (inclusive
                                 1,178,173.47     378,821.59          32.15           733,293.23     239,987.97        32.73
  of 3 years)
  3 to 4 years (inclusive
                                   641,804.42     474,608.03          73.95           103,939.29      81,969.65        78.86
  of 2 years)
  4 to 5 years (inclusive
                                   103,939.29      82,681.12          79.55           300,612.74     240,490.19        80.00
  of 3 years)
  Over 5 years                   7,268,003.39    7,268,003.39     100.00            7,297,362.77    7,297,362.77      100.00
         Subtotal              302,839,357.89   11,208,500.15          3.70       548,813,091.14   13,270,020.90         2.42

(3) Accrual, recovery or reversal of bad debt provision during the period

                                                                                               Amount of provision for bad
                                                                                                         debts
    Beginning balance                                                                                         14,041,321.58
    Provision for the year                                                                                     -2,061,520.75
    Recovered or reversal in the year                                                                                  0.00

    Write-off in the year                                                                                              0.00

    Closing balance                                                                                           11,979,800.83
      At 31 December 2022 and 31 December 2021, the Company had no overdue but not impaired accounts
      receivable.

(4) No actual written-off of accounts receivable in this period.

(5) Accounts receivable due from the top five debtors

      As of 31 December 2022, the total amount of the top five debtors in closing balance is RMB56,820,132.30,
      accounting for 18.71% of the total amount of closing balance of accounts receivable, and the corresponding
      closing balance of provision for bad debts is total RMB528,427.24.

(6) There were no accounts receivable derecognized due to the transfer of financial assets in each reporting period.

(7) There were no assets or liabilities formed by the continuing involvement of transferred accounts receivables in
     each reporting period.

3. Other receivables

                               Item                                   2022.12.31                       2021.12.31
      Dividends receivable                                                544,999,500.00                    814,041,000.00
      Other receivables                                                   240,307,524.78                    322,196,811.25
                               Total                                      785,307,024.78                   1,136,237,811.25

(1) Dividends receivable

                               Item                                   2022.12.31                       2021.12.31
      Topsino                                                                 524,999,500.00                749,999,500.00

      Haibin Pharma                                                                     0.00                  44,041,500.00
      Fenglei Electric Power                                                   20,000,000.00                  20,000,000.00

      Subtotal:                                                               544,999,500.00                814,041,000.00
      Less: Provision for bad debts                                                     0.00                           0.00

                               Total                                          544,999,500.00                814,041,000.00

(2) Other receivables

                                                                286
   Joincare Pharmaceutical Group                                                                                              Annual Report 2022


   ① by ageing

                                Item                                             2022.12.31                            2021.12.31
Within one year                                                                          239,838,488.56                           321,955,080.06
1 to 2 years                                                                                590,397.78                               149,812.10
2 to 3 years                                                                                149,812.10                               206,676.00
3 to 4 years                                                                                206,676.00                               126,228.36
4 to 5 years                                                                                126,228.36                                 20,000.00
Over 5 years                                                                              19,105,586.00                            19,085,586.00

Subtotal                                                                                 260,017,188.80                           341,543,382.52
Less: Provision for bad debts                                                             19,709,664.02                            19,346,571.27
                                Total                                                    240,307,524.78                           322,196,811.25

   ② Disclosure by nature

                                                2022.12.31                                                    2021.12.31
         Item
                                               Provision for                                                 Provision for           Carrying
                          Book balance                              Carrying amount        Book balance
                                                bad debts                                                     bad debts              amount
Other receivables
of each company               238,041,400.41             0.00          238,041,400.41      294,833,504.86              0.00        294,833,504.86
within the scope of
combination
Capital reduction                       0.00             0.00                     0.00      24,078,925.22              0.00         24,078,925.22
Treasury bonds and             17,968,386.04    17,968,386.04                     0.00      17,968,386.04     17,968,386.04                  0.00
security deposits
External entities               1,384,240.83     1,253,731.83              130,509.00         3,763,793.73     1,220,062.29          2,543,731.44
balances
Security deposits                973,098.11        354,429.35              618,668.76          848,272.56        157,320.34            690,952.22

Others                          1,650,063.41       133,116.80            1,516,946.61           50,500.11           802.60              49,697.51

         Total                260,017,188.80    19,709,664.02          240,307,524.78      341,543,382.52     19,346,571.27        322,196,811.25


   ③Information of provision for bad debts

   At year end, provision for bad debts on those in first stage:

                                                                       Expected
                                                                    credit loss rate     Provision for        Carrying
                    Category                   Book balance                                                                           Reason
                                                                     in the next 12       bad debts           amount
                                                                      months (%)
   Provision for bad debts on
                                                             0.00                0.00                 0.00                 0.00
   individual item
      Capital reduction                                      0.00                0.00                 0.00                 0.00
   Provision for bad debts on
                                               238,041,400.41                    0.00                 0.00   238,041,400.41
   portfolio basis
        Other receivables of each
                                                                                                                                    Expected to be
   company within the scope of                 238,041,400.41                    0.00                 0.00   238,041,400.41
                                                                                                                                        recovered
   combination
                      Total                    238,041,400.41                    0.00                 0.00   238,041,400.41

   At year end, provision for bad debts on those in second stage:

                                                                          Expected credit
                                                                                                 Provision for       Carrying
                      Category                     Book balance           loss rate for the                                               Reason
                                                                                                  bad debts          amount
                                                                            lifetime(%)
   Provision for bad debts on individual
   item

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                                                               Expected credit
                                                                                       Provision for     Carrying
               Category                     Book balance       loss rate for the                                          Reason
                                                                                        bad debts        amount
                                                                 lifetime(%)
Provision for bad debts on portfolio          4,007,402.35                     43.45    1,741,277.98      2,266,124.37
basis
   Security deposits, deposits and rental      973,098.11                      36.42     354,429.35        618,668.76
receivable
  Other receivables                           3,034,304.24                     45.71    1,386,848.63      1,647,455.61

                 Total                        4,007,402.35                     43.45    1,741,277.98      2,266,124.37

At year end, provision for bad debts on those in third stage:

                                                      Expected credit
                                                                               Provision for        Carrying
            Category                Book balance      loss rate for the                                               Reason
                                                                                bad debts           amount
                                                        lifetime(%)
Provision for bad debts on          17,968,386.04                  100.00       17,968,386.04               0.00
individual item
  Treasury bonds and security       17,968,386.04                  100.00       17,968,386.04               0.00 Not expected to
deposits                                                                                                          be recoverable
Provision for bad debts on                     0.00                   0.00                 0.00             0.00                 --
portfolio basis
              Total                 17,968,386.04                  100.00       17,968,386.04               0.00

As of 31 December 2021, information of provision for bad debts:

As of 31 December 2021, Provision for bad debts on those in first stage:

                                                            Expected
                                                         credit loss rate     Provision for         Carrying
            Category                 Book balance                                                                     Reason
                                                          in the next 12       bad debts            amount
                                                           months (%)
Provision for bad debts on
                                       24,078,925.22                  0.00                0.00     24,078,925.22
individual item
                                                                                                                    Expected to be
  Capital reduction                    24,078,925.22                  0.00                0.00     24,078,925.22
                                                                                                                        recovered
Provision for bad debts on
                                      294,833,504.86                  0.00                0.00    294,833,504.86
portfolio basis
     Other receivables of each
                                                                                                                    Expected to be
company within the scope of           294,833,504.86                  0.00                0.00    294,833,504.86
                                                                                                                        recovered
combination
              Total                   318,912,430.08                  0.00                0.00    318,912,430.08

As of 31 December 2021, provision for bad debts on those in second stage:

                                                          Expected credit loss
                                                                                       Provision for           Carrying
Category                               Book balance               rate for the                                          Reason
                                                                                          bad debts             amount
                                                                 lifetime(%)
Provision for bad debts on
                                                  0.00                        0.00                0.00             0.00
individual item
Provision for bad debts on
                                        4,662,566.40                         29.56      1,378,185.23     3,284,381.17
portfolio basis
  Security deposits, deposits and
                                            877,102.56                       17.99        157,778.54       719,324.02
rental receivable
  Other receivables                     3,785,463.84                         32.24      1,220,406.69     2,565,057.15
              Total                     4,662,566.40                         29.56      1,378,185.23     3,284,381.17

As of 31 December 2021, provision for bad debts on those in third stage:

                                                      Expected credit
                                                                               Provision for        Carrying
            Category                Book balance      loss rate for the                                               Reason
                                                                                bad debts           amount
                                                        lifetime(%)



                                                                288
 Joincare Pharmaceutical Group                                                                                    Annual Report 2022


 Provision for bad debts on         17,968,386.04                100.00      17,968,386.04                   0.00
 individual item
   Treasury bonds and security      17,968,386.04                100.00      17,968,386.04                   0.00 Not expected to
 deposits                                                                                                          be recoverable
 Provision for bad debts on                   0.00                   0.00               0.00                 0.00                  --
 portfolio basis
                Total               17,968,386.04                100.00      17,968,386.04                   0.00

 ④ Accrual, recovery or reversal of bad debt provision during the period

                                          First stage            Second stage                Third stage
                                                                Expected credit         Expected credit
      Provision for bad debts           Expected credit         loss for lifetime       loss for lifetime               Total
                                      loss within next 12          (no credit                (credit
                                            months                impairment            impairment has
                                                                   occurred)               occurred)
 Beginning balance                                      0.00          1,378,185.23             17,968,386.04          19,346,571.27
 Movement of beginning balance
 during the period
 --transfer to second stage                             0.00                  0.00                      0.00                    0.00
 --transfer to third stage                              0.00                  0.00                      0.00                    0.00
 --Reverse to second stage                              0.00                  0.00                      0.00                    0.00
 --Reverse to first stage                               0.00                  0.00                      0.00                    0.00
 Provision for the year                                 0.00           363,092.75                       0.00             363,092.75
 Reversal in the year                                   0.00                  0.00               -158,470.77            -158,470.77
 Transfer in the year                                   0.00                  0.00                      0.00                    0.00
 Write-off in the year                                  0.00                  0.00               -158,470.77            -158,470.77
 Other movement                                         0.00                  0.00                      0.00                    0.00
 Closing balance                                        0.00          1,741,277.98             17,968,386.04          19,709,664.02

 ⑤ No actual written-off of other receivables in this period

 ⑥ Other receivables due from the top five debtors

                                                                                                    Proportion to          Closing
                                                            Closing balance of                       total other          balance of
       Name of entity                    Nature                                      Ageing
                                                            other receivables                        receivables         provision for
                                                                                                        (%)               bad debts
Shenzhen Fenglei Electric            Other receivables
                                     of each company
Power Investment Co., Ltd. (深                                 129,956,104.29       2-3 years           49.98                      0.00
                                   within the scope of
圳市风雷电力投资有限公司)                 combination
Joincare Haibin Pharmaceutical       Other receivables
                                     of each company                                Within one
Co., Ltd. (健康元海滨药业有                                     45,397,838.87                           17.46                      0.00
                                   within the scope of                              year
限公司)                                   combination
Hua Xia Securities Co., Ltd. (华   Treasury bonds and                               Over 5
                                                                17,968,386.04                              6.91          17,968,386.04
夏证券股份有限公司)                   security deposits                             years
Joincare (Guangdong) Special         Other receivables
medicine Food Co., Ltd. (健康        of each company                                Within 2
                                                                15,751,011.27                              6.06                    0.00
                                   within the scope of                              years
元(广东) 特医食品有限公司)                combination
                                     Other receivables
Topsino Industries Limited (天       of each company
                                                                15,736,384.51       2-3 years              6.05                    0.00
诚实业有限公司)                    within the scope of
                                          combination



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     Joincare Pharmaceutical Group                                                                                 Annual Report 2022


                                                                                                       Proportion to         Closing
                                                                 Closing balance of                     total other         balance of
              Name of entity                     Nature                                   Ageing
                                                                 other receivables                      receivables        provision for
                                                                                                           (%)              bad debts
                  Total                                              224,809,724.98                        86.46           17,968,386.04

     ⑦ There were no other receivables derecognised due to the transfer of financial assets in each reporting
     period.

     ⑧ There were no assets or liabilities formed by the continuing involvement of transferred other receivables
     in the period.

4. Long-term equity investment

                                          2022.12.31                                                  2021.12.31
      Item                               Provision for                                                Provision for
                      Book balance                          Carrying amount       Book balance                      Carrying amount
                                         impairment                                                   impairment
  Investment
  in                  3,453,138,312.11       7,010,047.91     3,446,128,264.20    3,453,138,312.11     7,010,047.91 3,446,128,264.20
  subsidiaries
  Investment
                        78,056,248.43               0.00        78,056,248.43        84,810,888.09                0.00    84,810,888.09
  in associates
      Total           3,531,194,560.54       7,010,047.91     3,524,184,512.63    3,537,949,200.20     7,010,047.91 3,530,939,152.29

     (1) Investment in subsidiaries

                                                                                                         Provision
                                                                                                                           Closing
                                                                                                            for
                                                                                                                          balance of
      Investee              2021.12.31           Increase       Decrease           2022.12.31          impairment
                                                                                                                         provision for
                                                                                                        in the year
                                                                                                                         impairment

  Livzon Group              608,741,654.08             0.00            0.00         608,741,654.08                0.00            0.00
  Haibin Pharma             783,054,186.38             0.00            0.00         783,054,186.38                0.00            0.00
  Joincare Daily-
                               24,116,498.56           0.00            0.00           24,116,498.56               0.00   1,610,047.91
  Use
  Topsino                   813,552,689.31             0.00            0.00         813,552,689.31                0.00            0.00
  Taitai Genomics              37,500,000.00           0.00            0.00           37,500,000.00               0.00            0.00
  Taitai
                            105,939,709.72             0.00            0.00         105,939,709.72                0.00            0.00
  Pharmaceutical
  Shenzhen
                            170,100,000.00             0.00            0.00         170,100,000.00                0.00   5,400,000.00
  Hiyeah
  Fenglei Electric
                            100,763,433.06             0.00            0.00         100,763,433.06                0.00            0.00
  Power
  Jiaozuo Joincare          375,000,000.00             0.00            0.00         375,000,000.00                0.00            0.00
  Shanghai
                               32,500,000.00           0.00            0.00           32,500,000.00               0.00            0.00
  Frontier
  Taitai Biological             4,832,950.00           0.00            0.00            4,832,950.00               0.00            0.00
  Joincare Haibin           100,000,000.00             0.00            0.00         100,000,000.00                0.00            0.00
  Joincare Special
                                3,000,000.00           0.00            0.00            3,000,000.00               0.00            0.00
  Food
  Livzon Biologics          294,037,191.00             0.00            0.00         294,037,191.00                0.00            0.00

        Total             3,453,138,312.11         0.00            0.00          3,453,138,312.11          0.00          7,010,047.91




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Joincare Pharmaceutical Group                                                                              Annual Report 2022




(2) Investment in associates and joint ventures

                                                                                                 Movement in the year
                                                                                                                                                                                          Closing
                                                                                   Investment
                                                                                                Adjustment in                   Announced                                                balance of
              Investee            2021.12.31                                       income/loss                    Changes                         Provision                2022.12.31
                                                  Additions in    Decrease in                       other                      distribution of                                          provision for
                                                                                    recognized                    of other                           for      Others
                                                  investment      investment                    comprehensive                  cash dividend                                            impairment
                                                                                     under the                     equity                        impairment
                                                                                                   income                         or profit
                                                                                  equity method
 Associates
 Ningbo Ningrong Biomedical
 Co., Ltd. (宁波宁融生物医药有    27,464,098.71            0.00            0.00    -284,889.20             0.00         0.00             0.00          0.00     0.00   27,179,209.51           0.00
 限公司)
 Feellife Health Inc. (深圳来福
                                  10,689,582.15            0.00            0.00   1,712,742.07             0.00         0.00             0.00          0.00     0.00   12,402,324.22           0.00
 士雾化医学有限公司)
 Novastage Pharmaceuticals
 (Shenzhen) , Ltd. (新领医药技    18,080,883.21            0.00   18,080,883.21           0.00             0.00         0.00             0.00          0.00     0.00            0.00           0.00
 术(深圳) 有限公司)
 Jiangsu Baining Yingchuang
 Medical Technology Co., Ltd.
                                  28,576,324.02            0.00            0.00     156,057.09             0.00         0.00             0.00          0.00     0.00   28,732,381.11           0.00
 (江苏百宁盈创医疗科技有限
 公司)
 Shanghai Sheo Pharmaceutical
 Technology Co., Ltd. (上海偕怡            0.00   10,000,000.00                    -257,666.41             0.00         0.00             0.00          0.00     0.00    9,742,333.59
 医药科技有限公司)
              Subtotal            84,810,888.09   10,000,000.00   18,080,883.21   1,326,243.55             0.00         0.00             0.00          0.00     0.00   78,056,248.43           0.00




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     Joincare Pharmaceutical Group                                                                            Annual Report 2022



5. Operating income and operating cost

(1) Operating income and operating cost

                                                2022                                               2021
           Item
                              Revenue                          Cost                 Revenue                       Cost
      Primary                                                                      1,997,946,818.28           1,345,944,915.00
                             2,318,838,433.60             1,570,518,398.66
      operations
      Other
                                55,049,131.18                 42,380,613.14           23,227,007.34              10,880,121.11
      operations
           Total             2,373,887,564.78             1,612,899,011.80         2,021,173,825.62           1,356,825,036.11

(2) Primary Disaggregate information of operating income

     ① Segregation by products

                                                  2022                                                 2021
               Item
                                 Revenue                         Cost                 Revenue                      Cost
      Chemical
      pharmaceuticals           2,156,627,002.13              1,467,215,984.98       1,844,258,573.30           1,249,873,341.86
      (化学药物)
      Traditional Chinese
      medicine (中药制                42,843,606.38             24,726,803.46           38,481,963.54             22,519,595.22
      剂)
      Health care
      products (保健食               119,285,823.66             78,384,343.41          115,187,552.33             73,483,571.30
      品)
      Others                              82,001.43                   191,266.81             18,729.10                   68,406.62
               Total            2,318,838,433.60              1,570,518,398.66       1,997,946,818.28           1,345,944,915.00

     ② Segregation by operating location

                                                2022                                              2021
           Item
                              Revenue                         Cost                 Revenue                       Cost
      Domestic               2,318,555,876.08             1,570,367,026.33         1,997,946,818.28           1,345,944,915.00
      Overseas                       282,557.52                 151,372.33                      0.00                        0.00
           Total             2,318,838,433.60             1,570,518,398.66         1,997,946,818.28           1,345,944,915.00

     ③ Segregation by timing of revenue recognition

                                                2022                                               2021
           Item
                               Revenue                         Cost                 Revenue                       Cost
      Commodities
      (Recognized at a
                              2,318,838,433.60            1,570,518,398.66         1,997,946,818.28           1,345,944,915.00
      point in time) a
      point in time)
           Total              2,318,838,433.60            1,570,518,398.66         1,997,946,818.28           1,345,944,915.00

(3) Disaggregate information of other operations

                                                       2022                                            2021
                Item
                                      Revenue                        Cost              Revenue                      Cost




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     Joincare Pharmaceutical Group                                                                                   Annual Report 2022



     Processing fees                         4,837,029.47               4,329,387.37            1,403,169.59                1,712,962.53
     Rental fees                             9,861,266.50               1,445,184.13           13,104,696.50                1,989,089.05
     Technical services                     27,233,207.55              23,946,403.27                        0.00                     0.00
     Others                                 13,117,627.66              12,659,638.37            8,719,141.25                7,178,069.53
               Total                        55,049,131.18              42,380,613.14           23,227,007.34               10,880,121.11

6. Investment income

                                          Item                                                2022                       2021
     Gain from disposal of long-term equity investment                                        985,288,053.40           1,351,395,397.50
     Investment income from long-term equity investments under equity                                                     -2,005,822.14
                                                                                                1,326,243.55
     method
     Investment income from disposal of long-term equity investments                            4,242,404.46             -59,868,800.00

     Dividend income from other equity instrument investments                                    512,350.35                4,175,569.86

     Investment income from disposal of financial assets held for trading                                0.00                   50,958.36

                                          Total                                               991,369,051.76           1,293,747,303.58

XVI. Supplement information

1. Statement of non-recurring profit or loss

                                               Item                                                  2022                  2021
       Gain or loss on disposal of non-current assets                                                -705,357.30         14,492,047.24
       Unauthorized approval, or no formal approval documents, or occasional tax
                                                                                                              0.00                 0.00
       refunds, reductions and exemptions
       Government grants that are included in the profit and loss(except for
       government grants that are closely related to the company’s normal business
                                                                                                286,842,932.33          245,335,140.69
       operations and that meet the national policy requirements and continue to enjoy
       a certain amount or quantitative basis according to certain standards)
       Capital occupation fees from non-financial enterprises                                                 0.00                 0.00
       Gains resulting from the investment cost of the enterprise for the purpose of
       acquisition of the subsidiaries, joint operation and joint ventures is lower than
                                                                                                              0.00                 0.00
       the fair value of net identifiable assets of the investee as entitled at the time of
       receipt of the investment
       Profit or loss from exchange of non-monetary assets                                                    0.00                 0.00
       Gain or loss from entrusting others to invest or manage assets                                         0.00                 0.00
       Provision for impairment of assets accrued due to force majeure factors, such
                                                                                                              0.00                 0.00
       as natural disasters
       Gain or loss arising from debt restructuring                                                           0.00                 0.00
       Enterprise restructuring fees, such as the expenses for employees’ settlement
                                                                                                              0.00                 0.00
       and the integration fees
       Profit or loss exceeding the fair value and generated from the transaction of
                                                                                                              0.00                 0.00
       which the transaction price is obviously unfair
       Net profit or loss over the current period of the subsidiaries as a result of
       business combination under common control from the beginning of the year to                            0.00                 0.00
       the date of consolidation
       Gain or loss arising from contingencies unrelated to the company’s normal
                                                                                                              0.00                 0.00
       operation
       Except for the efficient hedging related to the Company’s normal business,
       profit or loss from changes in fair value as generated from financial assets and
       financial liabilities held for trading and gains from investment as a result of the      -109,887,696.11           8,110,644.25
       disposal of financial assets and financial liabilities held for trading and debt
       investments
       Reversals of provision for impairment of accounts receivable with individual
                                                                                                     158,470.77           1,013,650.67
       impairment test



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     Joincare Pharmaceutical Group                                                                               Annual Report 2022



                                              Item                                                 2022                 2021
       Profit or loss from entrusted loans                                                                0.00                 0.00
       Gain or loss from fluctuation in fair value of investment property which is
                                                                                                          0.00                 0.00
       measured at fair value
       Impact of a one-time adjustment on current profit and loss according to the
                                                                                                          0.00                 0.00
       requirements of tax and accounting, laws and regulations
       Custody fees of entrusted operation                                                                0.00                 0.00
       Other non-operating income and expenses other than the above                             -23,830,838.49      -30,737,442.83
       Other gain or loss items met the definition of non-recurring item                                  0.00                 0.00
       Total amount of non-recurring items                                                     152,577,511.20       238,214,040.02
       Less: effects of income tax on non-recurring items                                       31,919,034.26        39,580,260.30
       Less: Non-recurring items attributable to the minority shareholders (after tax)          37,113,548.72        95,131,719.24
       Non-recurring items attributable to the shareholders of the Company                      83,544,928.22       103,502,060.48

2. Rate of return on net assets and earnings per share

     For the year ended 31 December 2022

                                                                                                   Earnings per share
                                                             Weighted average
                  Profit in reporting period                                             Basic earnings per      Diluted earnings
                                                            return on equity (%)
                                                                                                share               per share
       Net profit attributable to the shareholders of the
                                                                            12.23                     0.7933                0.7921
       Company
       Net profit attributable to ordinary shareholders
       of the Company after deducting non-recurring                         11.55                     0.7492                0.7481
       gains and losses

     For the year ended 31 December 2021

                                                                                                   Earnings per share
                                                             Weighted average
                  Profit in reporting period
                                                            return on equity (%)         Basic earnings per      Diluted earnings
                                                                                                share               per share
       Net profit attributable to the shareholders of the
                                                                            11.50                     0.6864                0.6858
       Company
       Net profit attributable to ordinary shareholders
       of the Company after deducting non-recurring                         10.60                     0.6329                0.6324
       gains and losses




                                                                           Joincare Pharmaceutical Group Industry Co., Ltd.

                                                                                                                      7 April 2023




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