First Quarterly Report 2024 of Huadong Medicine Co., Ltd. Security code: 000963 Stock abbreviation: Huadong Medicine Announcement No.: 2024-041 Huadong Medicine Co., Ltd. First Quarterly Report 2024 The Company and all members of the Board of Directors hereby guarantee that the information presented in this report is authentic, accurate and complete and free of any false records, misleading statements or material omissions. Important Declaration: 1. The Board of Directors, Board of Supervisors, directors, supervisors and senior management of Huadong Medicine Co., Ltd. (hereinafter referred to as the "Company") hereby guarantee that the information presented in this report is authentic, accurate and complete and free of false records, misleading statements or material omissions, and shall undertake individual and joint legal liabilities. 2. The Company's legal representative, the officer in charge of accounting, and the head of accounting department (accounting supervisor) hereby declare that the financial information in this quarterly report is authentic, accurate and complete. 3. Has the First Quarterly Report been audited? □Yes No According to “Stock Listing Rules of the Shenzhen Stock Exchange”, if listed companies have both Chinese and other language version of public notice, they should ensure the content of both versions are the same. In the case of discrepancy, the original version in Chinese shall prevail. 1 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. I. Key Financial Data (I) Key accounting data and financial indicators Does the Company need to retroactively adjust or restate the accounting data of previous years? □Yes No Increase or decrease during the Current reporting period Same period last year current reporting period compared with the same period of last year (%) Operating revenue (RMB) 10,410,809,128.72 10,114,531,331.77 2.93% Net profit attributable to shareholders of the listed 862,411,560.96 755,284,976.47 14.18% company (RMB) Net profit attributable to shareholders of the listed company after deduction of 838,303,551.41 757,542,618.01 10.66% non-recurring profits and losses (RMB) Net cash flow from operating -484,522,666.13 -246,152,770.16 -96.84% activities (RMB) Basic earnings per share 0.4929 0.4316 14.20% (RMB/share) Diluted earnings per share 0.4928 0.4315 14.21% (RMB/share) Weighted average return on 4.01% 3.99% 0.02% equity Increase or decrease at the end of the End of the current End of the last year current reporting period compared reporting period with the end of the last year (%) Total assets (RMB) 34,467,844,280.37 33,509,361,816.98 2.86% Owners' equity attributable to shareholders of listed 21,955,243,888.90 21,047,609,756.66 4.31% companies (RMB) (II) Non-recurring profit and loss items and amounts Applicable □Not applicable Unit: RMB Item Amount during the current reporting period Description Profit and loss on disposal of non-current assets (including 1,521,275.31 the write-off of provision for impairment of assets) Government grants included in the current profits and losses (except those that are closely related to the normal business operation of the Company, comply with national 28,822,099.15 policies and regulations, are enjoyed in accordance with the defined criteria, and have a lasting impact on the Company's profits and losses) Profits and losses from changes in fair value arising from financial assets and financial liabilities held by non- financial corporations, and profits and losses from the -25,364.49 disposal of financial assets and liabilities, except for the effective hedging business related to the normal business operation of the Company 2 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. Other non-operating revenue and expenses other than those -1,436,525.67 mentioned above Minus: Amount affected by income tax 4,281,616.36 Amount affected by minority interests (after tax) 491,858.39 Total 24,108,009.55 -- Details of other profit and loss items conforming to the definition of non-recurring profits and losses □Applicable Not applicable The Company has no other specific circumstances of profit and loss items that meet the definition of non-recurring profits and losses. An explanation of the fact that the non-recurring profit and loss items listed in the Explanatory Announcement No.1 on Information Disclosure by Companies that Offer Securities to the Public - Non-recurring Profits and Losses are defined as recurring profit and loss items □Applicable Not applicable The Company did not define the non-recurring profit and loss items listed in the Explanatory Announcement No.1 on Information Disclosure by Companies that Offer Securities to the Public - Non-recurring Profits and Losses as recurring profit and loss items. (III) Details and reasons for changes in key accounting data and financial indicators Applicable □Not applicable Amount at the Amount at the Percentage Items in the balance sheet end of the beginning of the change period period Reasons for changes Mainly attributable to the decrease in Notes receivable 0.00 681.21 -100.00% commercial acceptance bills receivable during the current period Mainly attributable to discounting of bank Receivables financing 84,325.79 143,436.63 -41.21% acceptance bills during the current period Mainly attributable to an increase in Other accounts receivable 47,383.63 29,113.51 62.75% provisional payment receivable Mainly attributable to an increase in loans Short-term borrowings 108,359.71 82,238.03 31.76% during the current period Mainly attributable to a decrease in rental Advance receipts 40.52 139.36 -70.92% received in advance Employee compensation Mainly attributable to remuneration paid 21,539.69 35,914.85 -40.03% payable during the current period Mainly attributable to the payment of long- Non-current liabilities due term payables and long-term borrowings 20,941.37 35,934.26 -41.72% within one year due within one year during the current period Mainly attributable to additional leases Lease liabilities 8,300.63 5,669.52 46.41% during the current period Mainly attributable to the transfer of Long-term accounts 2,480.53 10,725.12 -76.87% outstanding acquisition amounts to non- payable current liabilities due within one year Other comprehensive Mainly attributable to an increase in 24.80 -4,034.15 100.61% income foreign currency translation differences Items in the profit Amount in the Amount in the Percentage Reasons for changes statement current period previous period change Mainly attributable to an increase in net Financial expenses 755.50 2,915.08 -74.08% interest income Mainly attributable to an increase in Other income 3,831.17 1,458.25 162.72% revenue-related government grants Proceeds from disposal of Mainly attributable to an increase in 152.13 -219.99 169.15% assets proceeds from disposal of fixed assets Items in the cash flow Amount in the Amount in the Percentage Reasons for changes 3 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. statement current period previous period change Mainly attributable to the increase in Net cash flow from -48,452.27 -24,615.28 -96.84% purchases of goods and cash paid to operating activities employees Net cash flows from Mainly attributable to added investment -70,737.61 -44,005.53 -60.75% investing activities during the current period Net cash flow from Mainly attributable to the year-on-year 7,149.63 -84,941.26 108.42% financing activities increase in loans during the current period II. Shareholder Information (I) Total number of common shareholders, number of preferred shareholders with restored voting rights and shareholdings of top 10 shareholders Unit: Shares Total number of preferred shareholders with restored Total number of common shareholders 93,834 voting rights at the end of the reporting period (if 0 at the end of the reporting period any) Shareholdings of top 10 shareholders (excluding shares lent through refinancing) Number of Pledged, marked or locked-up Shareholdi Name of Nature of Number of shares held status ng ratio shareholder shareholder shares held with restricted (%) Status of shares Quantity sale conditions Domestic non- China Grand state-owned 41.66% 730,938,157.00 0.00 Pledged 147,070,000.00 Enterprises, INC. legal person Hangzhou Huadong State-owned Medicine Group 16.42% 288,000,000.00 0.00 Not applicable 0.00 legal person Co., Ltd. Hong Kong Overseas legal Securities Clearing 2.75% 48,286,883.00 0.00 Not applicable 0.00 person Company Limited China Securities Domestic non- Finance Corporation state-owned 1.26% 22,186,818.00 0.00 Not applicable 0.00 Limited legal person Industrial and Commercial Bank of China Limited - Zhong Ou AMC Others 1.15% 20,099,373.00 0.00 Not applicable 0.00 Medical and Health Hybrid Securities Investment Fund China Construction Bank Corporation - E Fund CSI 300 Medical and Health Others 0.72% 12,696,732.00 0.00 Not applicable 0.00 Trading Open Index Securities Investment Fund China Construction Bank Corporation - ICBC Credit Suisse Others 0.68% 12,000,000.00 0.00 Not applicable 0.00 Frontier Medical Equity Securities 4 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. Investment Fund National Social Security Fund - Others 0.63% 10,983,604.00 0.00 Not applicable 0.00 Portfolio 110 Industrial and Commercial Bank of China Limited - Others 0.54% 9,494,245.00 0.00 Not applicable 0.00 Huatai-PB CSI 300 Open-ended Index Fund China Life Insurance (Group) Company - Traditional - Others 0.50% 8,819,214.00 0.00 Not applicable 0.00 General Insurance Products - 005L- CT001 Shanghai Shareholdings of the top 10 shareholders without restricted sales conditions Number of shares held without restricted sale Type of shares Name of shareholder conditions Type of shares Quantity RMB- China Grand Enterprises, INC. 730,938,157.00 denominated 730,938,157.00 ordinary share RMB- Hangzhou Huadong Medicine Group 288,000,000.00 denominated 288,000,000.00 Co., Ltd. ordinary share RMB- Hong Kong Securities Clearing 48,286,883.00 denominated 48,286,883.00 Company Limited ordinary share RMB- China Securities Finance Corporation 22,186,818.00 denominated 22,186,818.00 Limited ordinary share Industrial and Commercial Bank of RMB- China Limited - Zhong Ou AMC 20,099,373.00 denominated 20,099,373.00 Medical and Health Hybrid Securities ordinary share Investment Fund China Construction Bank Corporation - RMB- E Fund CSI 300 Medical and Health 12,696,732.00 denominated 12,696,732.00 Trading Open Index Securities ordinary share Investment Fund China Construction Bank Corporation - RMB- ICBC Credit Suisse Frontier Medical 12,000,000.00 denominated 12,000,000.00 Equity Securities Investment Fund ordinary share RMB- National Social Security Fund - 10,983,604.00 denominated 10,983,604.00 Portfolio 110 ordinary share Industrial and Commercial Bank of RMB- China Limited - Huatai-PB CSI 300 9,494,245.00 denominated 9,494,245.00 Open-ended Index Fund ordinary share China Life Insurance (Group) Company RMB- - Traditional - General Insurance 8,819,214.00 denominated 8,819,214.00 Products - 005L-CT001 Shanghai ordinary share Description of affiliation or concerted action of the The Company did not know whether there was any relationship among above shareholders the above shareholders, or whether they were parties acting in concert. As of the end of the current reporting period, none of the top 10 common Description of the participation in securities margin shareholders of the Company held shares of the Company through trading business of top 10 shareholders (if any) securities margin trading accounts. 5 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. Participation in the lending of shares through refinancing business of shareholders holding more than 5% of shares, top 10 shareholders and top 10 shareholders holding tradable shares without restricted sale conditions Applicable □Not applicable Unit: Shares Participation in the lending of shares through refinancing business of shareholders holding more than 5% of shares, top 10 shareholders and top 10 shareholders holding tradable shares without restricted sale conditions Shares held in ordinary Shares lent through Shares lent through Shares held in ordinary accounts and credit refinancing and not yet refinancing and not yet accounts and credit accounts Name of accounts at the beginning returned at the returned at the end of at the end of the period shareholder of the period beginning of the period the period (full name) Total Proportion Total Proportion Total Proportion Total Proportion number of in share number in share number of in share number in share shares capital of shares capital shares capital of shares capital China Grand Enterprises, 730,938,157 41.66% 0 0.00% 730,938,157 41.66% 0 0.00% INC. Hangzhou Huadong Medicine 288,000,000 16.42% 0 0.00% 288,000,000 16.42% 0 0.00% Group Co., Ltd. Hong Kong Securities Clearing 47,954,932 2.73% 0 0.00% 48,286,883 2.75% 0 0.00% Company Limited China Securities Finance 22,186,818 1.26% 0 0.00% 22,186,818 1.26% 0 0.00% Corporation Limited Industrial and Commercial Bank of China Limited - Zhong Ou AMC Medical 31,080,515 1.77% 0 0.00% 20,099,373 1.15% 0 0.00% and Health Hybrid Securities Investment Fund China Construction Bank Corporation - E Fund CSI 300 Medical 12,896,932 0.74% 328,500 0.02% 12,696,732 0.72% 0 0.00% and Health Trading Open Index Securities Investment Fund China 19,000,000 1.08% 0 0.00% 12,000,000 0.68% 0 0.00% 6 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. Construction Bank Corporation - ICBC Credit Suisse Frontier Medical Equity Securities Investment Fund National Social 13,619,804 0.78% 0 0.00% 10,983,604 0.63% 0 0.00% Security Fund - Portfolio 110 Industrial and Commercial Bank of China Limited - 6,639,145 0.38% 17,500 0.00% 9,494,245 0.54% 4,600 0.00% Huatai-PB CSI 300 Open-ended Index Fund China Life Insurance (Group) Company - Traditional - 7,582,314 0.43% 0 0.00% 8,819,214 0.50% 0 0.00% General Insurance Products - 005L-CT001 Shanghai Change in top 10 shareholders and top 10 shareholders holding tradable shares without restricted sale conditions due to lending/returning of shares through refinancing as compared to the previous period Applicable □Not applicable Unit: Shares Changes in top 10 shareholders and top 10 shareholders holding tradable shares without restricted sale conditions due to lending/returning of shares through refinancing as compared to the previous period Number of shares held in shareholders' Addition/with Number of shares lent through ordinary accounts and credit accounts drawal during refinancing and not yet returned at the Name of shareholder and shares lent through refinancing and the current end of the period (full name) not yet returned at the end of the period reporting period Total number of Proportion in share Total number of Proportion in share shares capital shares capital Industrial and Commercial Bank of China Limited - Huatai- Addition 4,600 0.00% 9,498,845 0.54% PB CSI 300 Open- ended Index Fund China Life Insurance (Group) Company - Traditional - General Addition 0 0.00% 8,819,214 0.50% Insurance Products - 005L-CT001 Shanghai 7 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. New China Life Insurance Co., Ltd. - Traditional - General Withdrawal 0 0.00% 6,920,836 0.39% Insurance Products - 018L-CT001 Shenzhen Bank of Shanghai Co., Ltd. - Yinhua CSI Innovative Pharmaceutical Industry Withdrawal 0 0.00% 7,318,298 0.42% Traded Open-ended Index Securities Investment Fund (II) Total number of preferred shareholders and shareholding list of top 10 preferred shareholders of the Company □Applicable Not applicable Ⅲ. Other Important Matters Applicable □Not applicable (I) Overview of the Company's overall operations during the reporting period In 2024, the reform of the domestic pharmaceutical industry continued to be expanded, which, coupled with market competition, drove the intensification of the differentiation of pharmaceutical enterprises. By focusing on the overall strategic planning and annual business objectives, the Company actively promoted the implementation of various operational management work, and achieved a good start in the first quarter. During the reporting period, the Company achieved operating income in the amount of RMB 10.411 billion, up 2.93% year-on-year; net profit attributable to parent company in the amount of RMB 862 million, up 14.18% year-on-year; net profit attributable to the parent company after deducting non-recurring profits and losses in the amount of RMB 838 million, up 10.66% year-on-year; and realized a positive growth in operating income and net profit compared with the fourth quarter of 2023. After deducting the equity incentive expenses and the profits and losses of participating and holding R&D institutions, net profit attributable to shareholders of the listed company upon deduction of non-recurring profits and losses during the reporting period was amounted to RMB 928 million, representing an increase of 22.45% compared with the net profit attributable to shareholders of the listed company upon deduction of non-recurring profits and losses in the first quarter of 2023. During the reporting period, the overall operation of the core subsidiary Zhongmei Huadong continued to maintain a stable growth trend, achieved operating income (including CSO business) in the amount of RMB 3.399 billion, showing a year-on-year increase of 10.53%; and achieved consolidated net profit attributable to the parent company in the amount of RMB 751 million, with a 8 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. year-on-year increase of 11.67%. During the reporting period, the Company's pharmaceutical business segment achieved an overall operating income of RMB 6.717 billion, down 1.86% year-on-year, and a net profit of RMB 107 million, up 1.51% year-on-year. The decreasing operating income of the Company's pharmaceutical business segment was mainly affected by the higher base in the first quarter of 2023. It is expected that the pharmaceutical business segment will return to show positive growth in the second quarter. The Company's aesthetic medicine business continued to maintain a good growth momentum during the reporting period. Its aesthetic medicine segment realized a consolidated operating income of RMB 630 million (excluding internal offsets), representing a year-on-year increase of 25.30%. Sinclair UK, a wholly-owned subsidiary, continued to expand the global aesthetic medicine market, realized a consolidated operating income of approximately RMB 272 million during the reporting period. Due to fluctuations in demands caused by the impact of the slowdown in global macro-economic growth, it underwent a year-on-year decline of 4.40%, with the overall income reaching the operating target for the first quarter. Growth rate is expected to gradually pick up from the second quarter. Sinclair (Shanghai), a wholly-owned subsidiary engaging in domestic aesthetic medicine, was actively expanding the domestic market. During the reporting period, it achieved operating income of RMB 257 million, representing a year-on-year increase of 22.65%, and a quarter-on-quarter increase of 13.38% compared with the fourth quarter of 2023. During the reporting period, the income of the Company's industrial microbiology business maintained a stable growth, up 23.00% year-on-year. Subsequently, along with the active expansion of the overseas market, increasing online and offline marketing promotion for the domestic animal health business and the launching of products of Hubei Magic Health, it is expected that the growth of industrial microbiology business will accelerate. (II) Important R&D progress of the Company during the reporting period During the reporting period, the Company accelerated its R&D efforts and continued to increase its R&D investment. The Company's R&D investment in the pharmaceutical industry (excluding equity investment) amounted to RMB 588 million during the reporting period, of which, direct R&D expenditure amounted to RMB 349 million, representing a year-on-year increase of 13.96%. The Company's innovative drugs and biosimilar business ushered in a number of important milestones. The main progress is described as follows: 1. The Company's BLA application in China for the recurrent pericarditis indication of Rilonacept (ARCALYST) for injection, a global innovative product introduced from Kiniksa, USA, was accepted in March 2024; 9 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. 2. The Company's Chinese IND application for HDM1005, which is the GLP-1R/GIPR dual- target, long-acting peptide agonist product independently developed by the Company, intended for weight management among overweight or obese people and for Type 2 diabetes, was approved in March 2024. The first subject was enrolled and administered in the phase Ia clinical study in China in March 2024. In addition, the US IND application of HDM1005 for overweight or obesity indications was approved in April 2024; 3. Chinese IND Application for HDM2005, the first ADC program that is independently developed by the Company and intended for the treatment of advanced solid tumors and hematological tumors, was submitted and accepted in March 2024; 4. In March 2024, the Company's U.S. partner announced that ELAHERE (Mirvetuximab Soravtansine Injection), an ADC drug intended for the treatment of platinum-resistant ovarian cancer, has been converted from accelerated approval to full approval in the United States. In April 2024, the Company was approved to join the international multi-center PSOC (platinum-sensitive ovarian cancer) Phase III clinical study, to promote this product for the frontline treatment of ovarian cancer. It is being developed as maintenance therapy for the treatment of subjects with recurrent platinum-sensitive, epithelial ovarian, primary peritoneal, or fallopian tube cancers with positive folate receptor alpha (FRα) in combination with bevacizumab; 5. The NDA application for Relmapirazin Injection in China, which is an innovative drug used in conjunction with a glomerular filtration rate dynamic monitoring system, was accepted in January 2024; 6. On March 1, 2024, CARsgen's CAR-T product Zevorcabtagene Autoleucel Injection (trade name: Saikaize, R&D code: CT053), has received notification from the National Medical Products Administration (NMPA) that it has been granted conditional approval for the treatment of adult patients with relapsed or refractory multiple myeloma, who have previously progressed after at least 3 lines of therapy (including a proteasome inhibitor and immunomodulator agent). The Company was granted the exclusive right to commercialize zevorcabtagene autoleucel in mainland China, and has set up a dedicated commercialization team. The first prescription was issued on the day when such product was approved for marketing. In addition, the Company's generic drug registration was proceeded as planned. Tacrolimus Extended-Release Capsules with a specification of 5mg were approved by the NMPA for marketing in February 2024. During the reporting period, the Company continued to promote the registration and implementation of key aesthetic medicine in China: 1. The Chinese clinical trial of MaiLi Extreme, the Company's new high-end lidocaine- 10 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. containing sodium hyaluronate for injection, successfully reached the primary study endpoint and showed good product safety data. The application for registration of this product as a Class III medical device in China has recently been accepted; 2. Two innovative botulinum toxin products under development, i.e., ATGC-110 (Type A botulinum toxin) and YY001 (Type A recombinant botulinum toxin), which were introduced by the Company in cooperation with South Korea ATGC and Chongqing Claruvis, have made significant progress respectively: the marketing application of ATGC-110 has been accepted by the Ministry of Food and Drug Safety (MFDS) of Korea. The declared indication is to improve the moderate to severe frown lines between eyebrows among adult patients. YY001 has completed the enrollment of Phase III clinical subjects in China. (III) Other important matters The Company held the 20th Meeting of the 10th Session of the Board of Directors on February 7, 2024, reviewed and approved the Proposal on Investment in Construction of Bio-Innovation and Intelligent Manufacturing Center Project, which agreed that Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd., a wholly-owned subsidiary of the Company, would invest in construction of the Bio-Innovation and Intelligent Manufacturing Center Project in accordance with its own development plan and new product launch plan. The total investment amount of this project is expected to be RMB 2 billion. This project would be carried out in stages. The investment amount of Phase I is about RMB 1.188 billion (the final investment amount is subject to the actual investment expenditure of the project construction) (for details, please refer to the relevant announcements disclosed by the Company at www.cninfo.com.cn, with the Announcement No.: 2024-006). (IV) Registration form of receptions, including research, communication, interview and other activities during the reporting period Main topics Reception Reception Receptio Reception Reception discussed and Basic information date location n mode object type object information index of the survey provided For details, please refer to the Record New China Sheet of Investor Site Asset Relations Activities January 9 Meeting survey Management, Investor on January 9 and and 10, room of the and Institution Industrial communicatio 10, 2024 published 2024 Company online Securities, n by the Company at meeting Guotai Junan https://irm.cninfo.co Securities, etc. m.cn/ and at www.cninfo.com.cn. January 16 Meeting On-site Haitong Investor For details, please Institution and 17, room of the survey Securities, communicatio refer to the Record 11 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. 2024 Company Origin Asset n Sheet of Investor Management, Relations Activities SWS MU on January 16 and Fund, etc. 17, 2024 published by the Company at https://irm.cninfo.co m.cn/ and at www.cninfo.com.cn. For details, see the Soochow Exchange Record Sheet of Securities, Meeting for Investor Relations Zhong Ou Launching Activities on March Meeting Institutions Asset New Drug March 4, Online 4, 2024, which was room of the and Management, Saikaize of 2024 meeting published by the Company individuals Perseverance Huadong Company at Asset Medicine and https://irm.cninfo.co Management, CARsgen m.cn/ and at etc. Therapeutics www.cninfo.com.cn. For details, see the Record Sheet of 2023 Annual Investor Relations Performance Activities on April Meeting Institutions CICC, China April 18, Online Exchange 18, 2024, which was room of the and Securities, TF 2024 meeting Meeting of published by the Company individuals Securities, etc. Huadong Company at Medicine https://irm.cninfo.co m.cn/ and at www.cninfo.com.cn. IV. Quarterly Financial Statements (I) Financial statements 1. Consolidated balance sheet Prepared by: Huadong Medicine Co., Ltd. March 31, 2024 Unit: RMB Item Closing balance Opening balance Current assets: Monetary funds 3,563,064,869.46 4,663,378,011.64 Deposit reservation for balance Lendings to banks and other financial institutions Trading financial assets Derivative financial assets 16,409,129.45 16,434,493.97 Notes receivable 6,812,089.97 Accounts receivable 9,677,692,232.29 7,455,250,690.83 Receivables financing 843,257,932.30 1,434,366,300.69 Prepayments 362,069,336.43 279,207,655.40 Premium receivable Reinsurance accounts receivable Reinsurance contract reserve receivable Other accounts receivable 473,836,282.59 291,135,104.33 Including: Interest receivable 12 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. Dividends receivable 2,623,608.84 2,623,608.84 Financial assets purchased for resale Inventory 4,224,074,951.91 4,290,214,266.03 Including: Data resources Contract assets Assets held for sale Non-current assets due within one year Other current assets 51,878,760.17 59,881,757.08 Total current assets 19,212,283,494.60 18,496,680,369.94 Non-current assets: Loans and advances issued Debt investments Other debt investments Long-term receivables Long-term equity investment 1,529,526,141.05 1,535,907,809.85 Investment in other equity instruments 565,223,872.68 565,223,872.68 Other non-current financial assets Investment real estate 12,485,783.85 12,746,181.87 Fixed assets 4,050,202,967.46 4,140,144,817.51 Works in progress 927,713,584.81 913,147,212.17 Productive biological assets Oil and gas assets Right-of-use assets 139,021,674.64 151,175,007.16 Intangible assets 2,527,437,482.39 2,333,787,357.62 Including: Data resources Development expenses 1,068,480,143.55 992,532,091.86 Including: Data resources Goodwill 2,596,809,693.91 2,598,696,062.31 Long-term unamortized expenses 19,291,856.38 20,053,854.34 Deferred income tax assets 187,808,574.44 187,808,574.44 Other non-current assets 1,631,559,010.61 1,561,458,605.23 Total non-current assets 15,255,560,785.77 15,012,681,447.04 Total assets 34,467,844,280.37 33,509,361,816.98 Current liabilities: Short-term borrowings 1,083,597,089.07 822,380,292.37 Borrowings from the central bank Borrowings from other banks and other financial institutions Trading financial liabilities Derivative financial liabilities Notes payable 1,437,934,424.82 1,727,420,960.30 Accounts payable 4,326,094,692.22 4,374,832,979.95 Advance receipts 405,231.33 1,393,551.48 Contract liabilities 170,289,424.40 135,459,275.17 Expense for financial assets sold for repurchase Deposits from customers and interbank Receivings from vicariously traded securities Receivings from vicariously underwriting securities Employee compensation payable 215,396,862.69 359,148,474.25 Taxes and dues payable 547,143,131.41 489,385,055.57 Other accounts payable 2,910,002,629.17 2,518,621,382.87 Including: Interests payable Dividends payable 143,024,219.60 143,024,219.60 Fees and commissions payable Reinsurance accounts payable Liabilities held for sale 13 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. Non-current liabilities due within one year 209,413,662.46 359,342,623.38 Other current liabilities 18,040,693.69 14,621,494.85 Total current liabilities 10,918,317,841.26 10,802,606,090.19 Non-current liabilities: Reinsurance contract reserves Long-term borrowings 519,383,524.08 520,759,460.07 Bonds payable Including: Preferred share Perpetual bonds Lease liabilities 83,006,313.46 56,695,158.59 Long-term accounts payable 24,805,289.23 107,251,248.59 Long-term employee compensation payable Estimated liabilities 38,460,444.39 37,184,074.06 Deferred income 167,391,739.98 171,056,435.34 Deferred income tax liabilities 182,493,233.05 184,373,974.04 Other non-current liabilities 46,192,650.00 47,170,650.00 Total non-current liabilities 1,061,733,194.19 1,124,491,000.69 Total liabilities 11,980,051,035.45 11,927,097,090.88 Owners’ equity: Share capital 1,754,327,548.00 1,754,425,348.00 Other equity instruments Including: Preferred share Perpetual bonds Capital reserve 2,448,599,611.00 2,446,313,774.82 Minus: Treasury stock 82,074,369.07 84,519,369.07 Other comprehensive income 247,990.92 -40,341,544.18 Special reserves Surplus reserves 1,277,779,972.18 1,277,779,972.18 General risk reserves Undistributed profit 16,556,363,135.87 15,693,951,574.91 Total owners' equity attributable to the parent company 21,955,243,888.90 21,047,609,756.66 Minority interests 532,549,356.02 534,654,969.44 Total owners’ equity 22,487,793,244.92 21,582,264,726.10 Total liabilities and owners’ equity 34,467,844,280.37 33,509,361,816.98 Legal Representative: Lv Liang Officer In Charge of Accounting: Lv Liang Head of Accounting Department: Qiu Renbo 2. Consolidated profit statement Unit: RMB Item Amount incurred in the current period Amount incurred in the previous period I. Total operating revenue 10,410,809,128.72 10,114,531,331.77 Including: Operating revenue 10,410,809,128.72 10,114,531,331.77 Interest revenue Premiums earned Fees and commissions revenue II. Total operating costs 9,331,357,509.92 9,111,221,456.77 Including: Operating costs 7,076,397,110.06 6,790,724,204.77 Interest expense Fees and commissions expenditures Surrender value Net payments for insurance claims Net provision for insurance liabilities 14 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. Policy dividend expenditures Reinsurance expenses Taxes and surcharges 56,334,556.14 53,150,033.98 Selling expenses 1,574,261,928.29 1,642,616,610.16 Management expenses 335,169,160.39 330,086,070.32 R&D expenses 281,639,751.64 265,493,695.70 Financial expenses 7,555,003.40 29,150,841.84 Including: Interest expense 23,050,131.41 34,466,716.93 Interest revenue 24,409,865.24 12,491,377.82 Plus: Other incomes 38,311,729.18 14,582,456.30 Investment income (loss expressed -47,163,448.93 -61,752,708.66 with “-”) Including: Investment income in -37,504,466.74 -52,816,907.73 associates and joint ventures Income from derecognition of financial assets measured on the basis of amortization costs Exchange earnings (loss expressed with “-”) Net income of exposure hedge (loss expressed with “-”) Income from changes in fair value -25,364.49 (loss expressed with “-”) Credit impairment loss (loss expressed with “-”) Asset impairment loss (loss expressed with “-”) Proceeds from disposal of assets (loss 1,521,275.31 -2,199,859.71 expressed with “-”) III. Operating profit (loss expressed with “-”) 1,072,095,809.87 953,939,762.93 Plus: Non-operating incomes 1,295,600.39 1,389,195.74 Minus: Non-operating expenses 5,202,610.91 6,049,187.60 IV. Total profit (total loss expressed with “-”) 1,068,188,799.35 949,279,771.07 Minus: Income tax expense 207,943,278.46 189,354,280.74 V. Net profit (net loss expressed with “-”) 860,245,520.89 759,925,490.33 (I) Classification by continuity of operation 1. Net profits from continuing operations 860,245,520.89 759,925,490.33 (net loss expressed with “-”) 2. Net profit from discontinued operations (net loss expressed with “-”) (II) Classification by ownership 1. Net profit attributable to the owners of 862,411,560.96 755,284,976.47 the parent company 2. Minority interest income -2,166,040.07 4,640,513.86 VI. Net of tax of other comprehensive income 40,589,535.10 -31,351,409.53 Net of tax of other comprehensive income attributable to the owner of the parent 40,589,535.10 -31,351,409.53 company (I) Other comprehensive income that cannot be reclassified into the profits and 693,671.15 losses 1. Change from re-measurement of 15 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. defined benefit plan 2. Other comprehensive income that cannot be included in the profits and losses under the equity method 3. Changes in fair value of investment 693,671.15 in other equity instruments 4. Changes in fair value by the enterprise’s credit risks 5. Others (II) Other comprehensive income that 40,589,535.10 -32,045,080.68 can be reclassified into the profits and losses 1. Other comprehensive income that can be transferred to the profit and loss under the equity method 2. Changes in fair value of investments in other debt investments 3. Financial assets reclassified into other comprehensive income 4. Provision for credit impairment of other debt investments 5. Cash flow hedging reserves 6. Converted difference in foreign 40,589,535.10 -32,045,080.68 currency financial statements 7. Others Net of tax of other comprehensive income attributable to minority shareholders VII. Total Comprehensive Income 900,835,055.99 728,574,080.80 Total comprehensive income attributable to 903,001,096.06 723,933,566.94 the owner of the parent company Total comprehensive income attributable to -2,166,040.07 4,640,513.86 minority shareholders VIII. Earnings per share: (I) Basic earnings per share 0.4929 0.4316 (II) Diluted earnings per share 0.4928 0.4315 If there is a business combination under common control in this period, the net profit of the combined party before the combination is RMB 0.00, and the net profit of the combined party in the previous period is RMB 0.00. Legal Representative: Lv Liang Officer In Charge of Accounting: Lv Liang Head of Accounting Department: Qiu Renbo 3. Consolidated cash flow statement Unit: RMB Item Amount incurred in the current period Amount incurred in the previous period I. Cash flows from operating activities: Cash received from selling goods and 9,896,088,428.64 9,958,329,191.55 providing services Net increase in deposits from customers as well as banks and other financial institutions Net increase in borrowings from the central bank Net increase in borrowings from other financial institutions Cash received from the original insurance contract premium Net cash received from reinsurance 16 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. business Net increase in savings and investment funds of policyholders Cash for interest, fees and commissions Net increase in borrowings from banks and other financial institutions Net increase in funds from repurchase business Net cash received from securities trading agency Refund of taxes and fees received 3,909,537.24 1,207,680.51 Other cash received related to business 179,167,865.43 166,606,563.49 activities Subtotal of cash inflow from operating 10,079,165,831.31 10,126,143,435.55 activities Cash paid for purchases of goods and 7,688,555,061.58 7,268,626,176.06 services Net increase in customer loans and advance payments Net increase in deposits with the central bank and interbank Cash for payment of the original insurance contract Net increase in lendings to banks and other financial institutions Cash for interest, handling fees and commissions Cash for payment of dividends on policies Cash paid to and for employees 1,232,560,542.55 845,672,966.99 Various taxes and fees paid 606,028,807.91 609,699,664.95 Payment of other cash related to business 1,036,544,085.40 1,648,297,397.71 activities Subtotal of cash outflows from operating 10,563,688,497.44 10,372,296,205.71 activities Net cash flow from operating activities -484,522,666.13 -246,152,770.16 II. Cash flows arising from investment activities: Cash received from investment recovery 1,000,000.00 Cash received from obtaining investment 2,000,000.00 income Net cash recovered from disposal of fixed assets, intangible assets and other 2,328,201.94 149,204.89 long-term assets Net cash received from disposal of subsidiaries and other business units Other cash received related to investment 44,313,052.83 activities Subtotal of cash inflows from investing 5,328,201.94 44,462,257.72 activities Cash paid for the purchase and construction of fixed assets, intangible 472,272,778.22 398,081,956.46 assets and other long-term assets Cash paid for investment 65,861,678.42 51,794,250.00 17 First Quarterly Report 2024 of Huadong Medicine Co., Ltd. Net increase in pledged loans Net cash paid for acquisition of 17,006,187.32 34,641,364.12 subsidiaries and other business entities Payments of other cash related to 157,563,682.87 investing activities Subtotal of cash outflows from investing 712,704,326.83 484,517,570.58 activities Net cash flows from investing activities -707,376,124.89 -440,055,312.86 III. Cash flows arising from financing activities: Cash received by absorbing investment Including: Cash received by subsidiaries from minority shareholders' investment Cash received from obtaining loans 1,510,044,486.23 907,116,269.61 Other cash received related to financing 62,459,038.61 59,222,104.05 activities Subtotal of cash inflows from financing 1,572,503,524.84 966,338,373.66 activities Cash paid for debt repayment 1,202,198,901.63 1,652,722,088.75 Cash paid to distribute dividends, profits 36,432,249.03 64,853,544.08 or pay interest Including: Dividends and profits paid 13,328,000.00 by subsidiaries to minority shareholders Payment of other cash related to 262,376,106.69 98,175,384.50 financing activities Subtotal of cash outflows from financing 1,501,007,257.35 1,815,751,017.33 activities Net cash flow from financing activities 71,496,267.49 -849,412,643.67 IV. Impact of exchange rate changes on 17,392,454.16 4,528,971.51 cash and cash equivalents V. Net increase in cash and cash equivalents -1,103,010,069.37 -1,531,091,755.18 Plus: Opening balance of cash and cash 4,208,160,010.91 3,416,910,702.33 equivalents VI. Closing balance of cash and cash 3,105,149,941.54 1,885,818,947.15 equivalents (II) Situation of relevant items of financial statements at the beginning of the current year after the initial implementation of adjustment of the New Accounting Standards in 2024 □Applicable Not applicable (III) Audit report Has the First Quarterly Report been audited? □Yes No The First Quarterly Report of the Company has not been audited. Board of Directors of Huadong Medicine Co., Ltd. April 26, 2024 18