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公司公告

昭衍新药:H股公告:2023年中期报告2023-09-28  

(A joint stock company incorporated in the People’s Republic of China with limited liability)
Stock Code: 6127




2023
2

6

7

9

10

11

24

49

51

53

55

56
2018               2018     2    27




2019               2019     8    15




2020               2020     7    15




2021   A           2022     1    19
             2021 12       30


2021   A           2022     1    19
                   2021 12       30


2022   A            2022    11    18
                   2022 10       31


2022   H            2022    6    24              H
             2022 5    26


A                                       1.00




Biomere    Biomedical Research Models, Inc.          1996   12    11
                                               2019    12   10
                      Joinn Laboratories (Delaware) Corporation




                                                                       2023   2
                             2




                                              2008   2   14
         2012      12   26                      A
                   603127        H                            6127




        2021   A                     2022 A




    H                                  1.00




3
                                   2008   12   11




H


2021   2   26




2021   A                    2021    A                  2022   A




2018                               2019
    2020


                2021 2 16


    2023 6       30




                                                    2023          4
             571




                           1.00            A       H




                                     2002      8    16


    300204                        40.23%
                                                   47.60%   37.40%
       37.15%                                                16
                   1.97%                    1.11%




5
Y




    2023   6
              H




                  16
                       17




          5
    100176




    348
     5




          5
    100176




7
H    6127


A    603127                  15


              32 3203-3207




                        35


    10        A   509
     8              100033




              www.joinnlabs.com




                                  2023   8
                   6   30
       2023                 2022




     1,012,077           776,881      30.3%
      447,799            377,942      18.5%
       89,508            370,384     –75.8%
       90,627            371,120     –75.6%




           44.2%            48.6%      4.4


           8.8%             47.7%     38.9




            0.17              0.70   -75.7%
            0.17              0.69   -75.4%


       2023                 2022
       6    30          12 31




    10,219,310         10,364,216     –1.4%
     2,195,250          2,173,350      1.0%
     8,024,060          8,190,866     –2.0%
     8,018,014          8,183,701     –2.0%




9
2023




       10.12      30.27%   1.95   30.82%
               38.7




                                   2023    10
 I.




                                 2,500




      II   20,000              12,000             2023




                                         22,000
                    2024




                           Non-GLP




11
(1)



                              2023
                 GLP                  GLP




            AI                  CNS


      MRI              100%




                                             DDI




                                      2023         12
     (2)



           IIT         I   II




                 ADC   PROTAC




13
(3)

      2023




             NHP



(4)



                          CNAS
      GLP




                   2023          14
            2023




     38.7




     2023


                   13   2023


     1.




     2.




     3.                                    IPSC




     4.                        2.4   16%




15
II.




                                                                                 2023     6    30
                     1,012.1   2022    6   30                      776.9               30.3%




                                                         6    30

                                                2023                              2022

                                                              %                                        %


                                       976,681            96.5              755,335                  97.2
                                        31,332               3.1             19,839                   2.6
                                           4,064             0.4              1,707                   0.2


                                      1,012,077          100.0              776,881                 100.0




              2023   6   30                      564.3               2022    6    30
      398.9          41.4%




                                                                                        2023                16
         2023      6   30                                                   447.8               44.2%                          2022   6   30
                                     377.9              48.6%
                                             2023       6    30
                                                            JOINN LABORATORIES, CA Inc.




         2023      6   30                                                    99.8                       2022      6       30
         120.4                  17.1%                                                     2022    6   30
        14.4




                                                                        2023        6    30
                                 198.8                      2022   6   30
     131.3




                   2023     6   30                                             11.9                        2022       6    30
             8.2                45.0%




                                                                                          2023   6    30
                   159.7                 2022       6       30                          158.8              0.6%                       2023
     6 30                                      2022




17
            2023   6    30                                  56.9                    2022       6       30
25.5             123.4%




            2023   6    30                                  1.68                    2022       6       30
1.73             2.7%        2023    6   30                                   2022




            2023   6    30                                    27.4                      2022       6    30
   64.8            57.6%


            2023   6    30                          23.5%          2022   6   30                        14.9%




                                         2022   6   30                            370.4                     75.8%    2023
   6   30                     89.5                                   2022     6    30                        47.7%
2023 6      30               8.8%


                                                                              195.3


                                                            183.0




                                                                                                             2023       18
                 2023       6       30    3,040.5                   2022    12     31
     2,916.8               4.2%




         2023    6    30                                    21.5%           2022    12   31
     21.0%




                     2023       6    30
               2023    6       30                   115.9                  2022
     151.3




         2023    6    30




                2023       6    30




19
           2022

         2023   6   9                   2022                    2022                   2023             A
             2023                 H                    2022
                                                                       2023   7   21    2023     7    25
       33,998,630       H        180,245,794   A                       749,888,699




           2023     6       30                 2,500




                                                        291.3          2022                   241.9




III.




                                                                                                 2023       20
     CRO




21
IV.




             II   20,000   12,000   2023




      2019    Biomere
                                    Biomere




                                     2023     22
     Biomere




                      (i)
               (ii)




23
                 2023   6   30




                                       13.13    13.14     13.15   13.20    13.21




2023    6   30                                                                             XV
                                 352




                                                            (2)               (3)                  (3)




  (1)                             A            119,400,452 (L)            26.49%            22.29%
                                  A             53,375,701 (L)            11.84%                9.96%


                                  A             12,778,329 (L)            2.84%                 2.39%


                                  A              2,833,899 (L)            0.63%                 0.53%


                                  A                303,504 (L)            0.07%                 0.06%




                                  A                131,270 (L)            0.03%                 0.02%




                                                                                    2023                 24
 (1)                                                                                                 A                            119,400,452
           A                       2023   6    30                    22.29%
                      A                             53,375,701   A             2023   6   30                9.96%
                                                                        A                                              172,776,153
                                   2023    6   30                     32.25%
                          A


     (2)       L


     (3)       2023   6       30                     535,678,676                  450,682,100   A    84,996,576    H
                                                                         A


                                                                                                                  2023   6   30
                                                                                                    XV
                                      XV        7       8
                                                                                352




25
                                         2023       6   30
                                                 XV         2       3
336                                                                                     5%



                                                                                     (1)                        (2)              (2)




                                                        A                53,375,701 (L)(3)            11.84%                  9.96%
                                                        A               119,400,452 (L)(3)            26.49%                 22.29%

  UBS Group AG                                          H                 9,289,904 (L)               10.93%                 1.73%


  abrdn plc                                             H                 6,797,648 (L)                8.00%                 1.27%



  FIDELITY FUNDS                                        H                10,730,600 (L)               12.62%                 2.00%

  Brown Brothers Harriman                               H                  8,369,320(L)                9.85%                 1.56%
    & Co.                                                                  8,369,320(P)                9.85%                 1.56%

  Morgan Stanley                                        H                  6,813,087(L)                8.02%                 1.27%
                                                                           4,938,783(S)                5.81%                 0.92%

  FIL Limited                                           H                 13,462,778(L)               15.84%                 2.51%

  Pandanus Associates Inc.                              H                 13,462,778(L)               15.84%                 2.51%

  Pandanus Partners L.P.                                H                 13,462,778(L)               15.84%                 2.51%

  The Goldman Sachs                                     H                  4,956,413(L)                5.83%                 0.93%
   Group, Inc.                                                             3,443,161(S)                4.05%                 0.64%

  JP Morgan Chase & Co.                                 H                  1,637,141(L)                1.93%                 0.31%
                                                                          1,809,174(S)                 2.13%                 0.34%
                                                        H                 1,057,300 (L)                1.24%                 0.20%
                                                        H                    65,800 (L)                0.08%                 0.01%

                                                        H                   428,080 (L)                0.50%                 0.08%
                                                                            428,080 (P)                0.50%                 0.08%




(1)     (L)          (S)        (P)

(2)           2023   6     30         535,678,676                         450,682,100      A   84,996,576   H
                                                                A

(3)                                        (1)


                                                                                                                      2023             26
                                                            10%


                                                                                (%)


                                          1,000,000                              35


                                        10,000,000                               45


                                        50,000,000                               20




                        2023   6   30
       XV    2   3                                    336
            5%




                 2018              2019                           2020




 (a)




 (b)

                                                                         2020




27
(c)




(d)

                               5%



(e)

                               A


(f)



                  1%
                       10%


(g)




       48


      2018         2019      2020
             12


(h)



                                           60




                                    2023        28
 (i)

                                                                                           12    24
             36




                  (i)                           50%                     12
                                          24                  (ii)                              30%
                                24                                               36
                        (iii)                    20%                        36
                                           48


        2019                                           2020
                        (i)                      50%                        12
                                           24                        (ii)
       50%                           24                                               36



 (j)




                                                                                                48




29
(k)



            (i)                                                        1         A              1
                                 1                     (ii)
                  20         A                    20   A                    20       A




                       (i)                                                       1         A
            1                             1                    50%   (ii)
                                     20       A               20      A                   20        A
                       50%


(l)

      (1)




      (2)


      (3)


      (4)




      (5)




                                                                                         2023           30
 (m)

       (1)


       (2)


       (3)


       (4)                A




       (5)        A
              A       A


       (6)


       (7)




       (8)


       (9)




       (10)




       (11)




31
    2023   6   30
A


                                        2023                                   2023
                                         1 1                                  6 30




                    47.91 2020 7 17     188,160   0   0   4   0          0     188,160


                    47.91 2020 7 17      29,400   0   0   4   0          0      29,400




                    47.91 2020 6 24     211,680   0   0   3   0          0     211,680
                    47.91 2020 7 17      58,800   0   0   4   0          0      58,800


                    47.91 2020 7 17      58,800   0   0   4   0          0      58,800




                                       546,840    0   0       0          0    546,840




                    47.91 2020 6 24       9,800   0   0   3   0          0       9,800
                    47.91 2020 7 17      14,700   0   0   4   0          0      14,700


                                        24,500    0   0       0          0     24,500


                    14.12 2018 3 9      667,335   0   0   1   0          0     667,335
                    16.97 2019 9 9                        2
                    47.91 2020 6 24                       3
                    47.91 2020 7 17                       4


                                      1,238,675   0   0       0          0   1,238,675




                                                                  2023                   32
 (1)       2018                                                                                                                                            (i)                  50%       2019
           4    19         2020          4      18                        (ii)                    30%     2020       4    19    2021         4   18                 (iii)                 20%
           2021 4          19           2022          4 18


 (2)       2019                                                                                                                                  (i)              50%       2020     10   14
           2021       10    13                                (ii)                      30%   2021      10    14         2022   10   13                  (iii)                  20%       2022
           10 14           2023          10          13


 (3)       2019                                                                                                                                            (i)                  50%       2021
           8   11          2022         8      10                            (ii)                  50% 2022 8              11    2023 8 10


 (4)       2020                                                                                                                        (i)               50%       2021     8   31        2022
           8    30                           (ii)                     30%           2022      8   31      2023       8    30                     (iii)             20%      2023     8    31
           2024 8          30


 (5)                                                                 48


 (6)


 (7)           2018    3        9        2019             9     9     2020          6    24       2020    7     17                                                                 59.87
                62.81                          96.53                      95.42


     (8)        2023        1       1                 2018                                                    2019                                               2020
                                    29,001                40,926           1,420,020


 (9)            2023        6       30                    2018                                                2019                                               2020
                                                     1,420,020


 (10)                                               2018                                                 2019                                            2020




33
    2023   6   30
A


                                      2023                                       2023
                                      1 1                                        6 30




                    9.81 2018 3 9            0   0   0       1    0          0          0
                    8.21 2019 9 9            0   0   0       2    0          0          0


                    9.81 2018 3 9            0   0   0       1    0          0          0
                    8.21 2019 9 9            0   0   0       2    0          0          0




                    9.81 2018 3 9            0   0   0       1    0          0          0
                    8.21 2019 9 9            0   0   0       2    0          0          0


                    9.81 2018 3 9            0   0   0       1    0          0          0
                    8.21 2019 9 9            0   0   0       2    0          0          0


                                             0   0   0            0          0          0




                    9.81 2018 3 9            0   0   0       1    0          0          0
                    8.21 2019 9 9            0   0   0       2    0          0          0
                    23.74 2020 6 24          0   0   0       3    0          0          0
                    23.74 2020 6 24          0   0   0       3    0          0          0


                                             0   0   0            0          0          0


                    9.81 2018 3 9            0   0   0   (   1)   0          0          0
                    8.21 2019 9 9      3,293     0   0   (   2)   0          0    3,293
                    23.74 2020 6 24          0   0   0   (   3)   0          0          0


                                       3,293     0   0            0          0    3,293




                                                                      2023                  34
 (1)           2018                                                                                                                         (i)
                       50%     2019   4    19       2020 4 18                     (ii)                 30%    2020    4       19        2021 4        18
                       (iii)                        20% 2021 4            19    2022        4 18

 (2)           2019                                                                                                                        (i)
                       50% 2020       10       14    2021 10 13                      (ii)               30%    2021       10       14     2022    10       13
                          (iii)                         20% 2022          10   14      2023    10 13

 (3)           2019                                                                                                                        (i)
                       50%     2021   8    11       2022    8     10                 (ii)               50%    2022       8    11        2023     8    10



     (4)                                                          48



     (5)


     (6)        2018   3    9    2019      9   9     2020     6    24                                                               59.87                  62.81
                           96.53

     (7)          2023     1   1          2018                                      2019



     (8)          2023     6   30          2018                                      2019



     (9)               2018                                        2019




                2022       1   19       2022        11   18             2021   A                         2021        A                                     2022
           A


                2022 1         19          2021      A                                      2021 A




35
(a)

      2021   A




(b)

      2021   A                     A             A



(c)

         A                                   A                          2021   A
                          A




(d)

      2021   A                     505                           2021   A
                                                     5%




                                                                            2021      A
                              11         4                2022   A
                 20   4




                                                                               2023       36
 (e)

       2021       A                           A




 (f)

       2021       A                           675,400        A
       A                                                              0.13%



       10%     2021       A                                                   A
                                1%


       2021       A                               2022   A                                            124,000
           2023       6   30                0.023%



 (g)

                                                                                          2021    A


               48              2021   A                                       24


                                      48                                           2021       A



 (h)

       2021       A                        2022                           2022            A                 2022
           H                                      2022   1       28                                      2022   1   28




37
(i)

         2021         A
                 12        24         36                  2021   A                                     A




      2021   A                                                                                                    (i)
                          40%                     12                       1                                             24
                                           (ii)                      30%                              24                1
                                           36                                            (iii)                      30%
                            36                    1                                              48



      2021   A                                                                         (i)
      40%                             12                  1                     (ii)                                    30%
                                 24                   1                        (iii)                                    30%
                                36                    1


      2022   A                                                                         (i)
      50%                             12                  1                     (ii)                                    30%
                                 24                   1                        (iii)                                    20%
                                36                    1




                                                                                                           2023               38
 (j)

        2021       A                                    A




 (k)

       2021    A
              (i) 2021    A                             1       A         1
              1                   50%   (ii) 2021   A                         20     A
                         20   A             20              A       50%


                                                                1              50%




39
              2023          6   30     2021        A                                                                                                 A


                                                              2023                                                                                                     2023
                                                              1 1                                                                                                      6 30
                                                                                                  (3)




              297                    59.72 2022 1 28          512,820            0          187,880         (    1 2)                   0                   0          324,940




1.    2021    A                                                                                                      (i)                             40%        2023    3     29
         2024         3    28               (ii)                  30%     2024   3    29        2025        3   28                           (iii)                          30%
       2025       3    29       2026   3   28


(2)                                                      48



(3)   2023    3       30                                                                    2021        A
             2021      A                                                                                        2023       4   21           187,880      A                  A
       2023       4    20                                 55.9969


(4)      2021         A                                                               512,820                     2023         6   30



(5)    2022       1    28                                                               97.24


              2021          A                                                        2022     A
                                                       2023   6      30                                 0.013%




      0.23%         0.096%




                                                                                                                                                     2023                          40
 2022          H

           2022 6          24   2022   H




 (a)

        2022           H                   (i)
        (ii)                                               (iii)



 (b)

        2022 H                    H


 (c)




 (d)

        2022           H                         H



 (e)

        2022           H                             600
                   H




                                       H


        2022 H




41
(f)

           2022       H




                                                    (i)                                                                    (ii)
                                                              (iii)




(g)

               2022       H                                           2022   H                           2022   6    24            10
       2022 H                                             9


(h)    H

       2022 H                                 H


2022       H

                              2022   H                                                H                                      2,409,500
  H                    80,900,000                                                         0.45%




  2023     3    30        2023       4   27
               3,293      2019                                  A            31,108   2021                  A
           2023      7    6                                       1,884,805.29                           2023   3    30           2023   4
  27                                 2023     7 3


                                                    H                                 H      2,409,500          80,900,000




                                                                                                                    2023                 42
                                    2023 6 30




                                                2023   6   30




                    3.21




                    2023   6   30                          2023   6
 30




      2023 6   30




43
(i)

                   2023     6    30                              2023     4      27



(ii)

                   2023     6    30


(iii)

                   2023     6    30


(iv)

                   2023     6    30


                   2023      6   30
                                                       II.




H       2021            2   26                                                        2021   3   19
40,800         H                       2021   3   24         H   151.00
                                       6,373.6                            5,285.2




         (i)       2022     4    28                                                                                  (ii)
2022     4         28
                                                                                       787.9
                                 (i)                                      (ii)                               (iii)




                                                                                                      2023                  44
                   2023   6   30              2,412.7




                                                                 2023
                                                                6 30




                                   (%)


     (A)                           16.0   845.6         57.7       57.7       –   –




           (i)                      7.9   417.5         16.0           16.0   –   –




           (ii)                     1.7    89.8         36.7           36.7   –   –




           (iii)                    5.5   290.7          5.0            5.0   –   –




           (iv)                     0.9    47.6            –            –   –   –




45
                                                            2023
                                                           6 30




                                (%)


(B)                             10.0    528.5     528.5       71.5       26.1     457.0
              Biomere




      (i)                        7.6     401.7     401.7          71.5   26.1      330.2   2023




      (ii)      Biomere          2.4     126.8     126.8            –      –     126.8   2023




(C)                             39.0   2,061.3   2,061.3     174.1       26.4    1,887.2




      (i)                       17.0     898.5     898.5      141.3      19.2      757.2   2023
                          GLP
                GLP


      (ii)                      17.0     898.5     898.5          11.1    0.3      887.4   2023




      (iii)                      2.6     137.4     137.4          21.7    6.9      115.7   2026




      (iv)                       2.4     126.9     126.9            –      –     126.9   2026




                                                                                    2023          46
                                                2023
                                               6 30




                         (%)


     (D)                 5.0   264.3   264.3      33.0       6.0    231.3




           (i)     220   0.6    31.7    31.7           8.3   0.6     23.4   2024




           (ii)          0.4    21.2    21.2            –     –    21.2   2024



           (iii)         4.0   211.4   211.4          24.7   5.4    186.7   2024




47
                                                                     2023
                                                                    6 30




                                         (%)


(E)           (i)                        20.0   1,057.0   1,844.9    1,844.0            50.5        0.9   2024


      (ii)


      (iii)




(F)                                      10.0    528.5     528.5      232.4                  –   296.1


                         2023   6   30                                         2023 8   30




         2023 8     30




                                                                                                   2023          48
     2023 6   30




                            2023           2022
                           6    30        6    30




                    4     1,012,077       776,881
                          (564,278)       (398,939)


                   4(b)    447,799        377,942


                    5       99,769        120,412
                          (198,770)       131,321
                            (11,866)          (8,184)
                          (159,703)       (158,784)
                            (56,933)       (25,482)


                           120,296        437,225


                   6(a)        (1,681)        (1,727)
                               (1,679)          (350)


                    6      116,936        435,148


                    7       (27,428)       (64,764)


                            89,508        370,384




                                     –        5,235



                            13,252            12,852


                            13,252            18,087


                           102,760        388,471



49
           2023    6     30




    2023                      2022
    6    30                   6   30




     90,627                   371,120
        (1,119)                   (736)


     89,508                   370,384




    103,879                   389,207
        (1,119)                   (736)


    102,760                   388,471


8
         0.17                     0.70
         0.17                     0.69




                  2023                    50
     2023 6   30




                              2023        2022
                             6 30       12 31




                    9      1,270,082    1,234,691
                              49,710       50,442
                              20,919       22,598
                             138,755      133,739
                    10       671,743      787,419
                             158,720      158,720
                    11       511,232      485,923
                           1,514,795    1,478,774
                    12        68,195       50,891
                   22(b)      33,179       32,613


                           4,437,330    4,435,810



                    13       307,292      350,182
                    14       889,337      773,248
                    10       931,112    1,071,176
                   15(a)     104,877      128,477
                    16       169,835      211,623
                    17       102,856       68,381
                              21,688            –
                    11       214,442      408,471
                    18     3,040,541    2,916,848


                           5,781,980    5,928,406



                                   –       3,533
                    19        49,150      127,309
                   15(b)   1,394,820    1,294,707
                    20       404,371      335,504
                              27,002       24,006
                   22(a)      25,055       59,203


                           1,900,398    1,844,262


                           3,881,582    4,084,144


                           8,318,912    8,519,954




51
                       2023   6   30




          2023               2022
         6 30              12 31




               –             3,281
          53,410             56,887
22(b)    163,246            188,243
          78,196             80,677


         294,852            329,088


        8,024,060          8,190,866



 24       535,679            535,679
        7,482,335          7,648,022


        8,018,014          8,183,701

           6,046              7,165


        8,024,060          8,190,866




                    2023               52
      2023 6      30




                               (24)


     2023 1 1               535,679    5,480,135     (53,154)   119,511     3,145    92,412    2,005,973    8,183,701    7,165     8,190,866


      2023 6 30
                                  –           –          –         –        –        –     90,627       90,627     (1,119)     89,508
                                  –           –          –         –   13,252         –           –     13,252          –     13,252


                                  –           –          –         –   13,252         –     90,627      103,879     (1,119)    102,760


                                  –      (2,655)      5,386          –        –        –           –      2,731          –      2,731
                                  –           –    11,220           –        –        –           –     11,220          –     11,220
                                  –           –    (72,327)         –        –        –           –     (72,327)        –     (72,327)
                       21         –      3,156            –         –        –        –           –      3,156          –      3,156
                                  –         (88)          –         –        –        –           –         (88)        –         (88)
                                  –           –          –         –        –        –   (214,258)    (214,258)         –   (214,258)


     2023 6 30              535,679    5,480,548    (108,875)   119,511    16,397    92,412    1,882,342    8,018,014    6,046     8,024,060




53
                                                                                                   2023       6      30




2022 1 1          381,246    5,543,570    (3,935)   87,428    (20,569)   47,312    1,101,162    7,136,214           8,222    7,144,436


 2022 6 30


                        –          –         –        –         –        –    371,120      371,120             (736)    370,384
                        –          –         –        –   12,852      5,235            –     18,087                –     18,087


                        –          –         –        –   12,852      5,235     371,120      389,207             (736)    388,471


                     366       30,392    (30,758)        –         –        –           –           –              –           –
                      30        1,954          –        –         –        –           –       1,984               –       1,984
             21         –      6,284          –        –         –        –           –       6,284               –       6,284


                        –      1,856          –        –         –        –           –       1,856               –       1,856
                        –          –         –        –         –        –    (137,249)    (137,249)              –    (137,249)


2022 6 30         381,642    5,584,056   (34,693)   87,428     (7,717)   52,547    1,335,033    7,398,296           7,486    7,405,782




                                                                                                             2023                         54
     2023 6   30




                        2023       2022
                    6     30      6 30




                    336,537       589,749
                    (90,527)       (44,255)


                    246,010       545,494



                    (90,060)      (753,179)
                          –      (317,425)
                   (120,000)      (215,000)
                    (25,000)      (155,000)
                   (100,990)      (115,337)
                     (3,060)         (1,495)
                    (30,000)              –
                    293,525        609,347
                     27,516           6,827
                      1,300               –
                         44              10
                      4,418               –
                        200               –


                     (42,107)     (941,252)



                           –         1,983
                           –       30,758
                      (6,816)        (1,702)
                     (72,328)             –
                        (672)           (74)
                         (85)          (156)
                     (13,531)      (11,862)
                        (171)          (150)


                     (93,603)      18,797


                        17,779     23,824


                    128,079       (353,137)

     1 1           2,899,470     4,150,396


     6 30          3,027,549     3,797,259




55
1.



                                              2017   8       25                  A
                 603127.SH               H    2021       2    26
                 6127.HK




2.



                                    34                                    2023       8   30




     2023                                                                                     2022
                                                     3


            34




                                                                   2022




                             2022   12   31




                                                                                     2023            56
 3.




                              17


                       8


                       12


                       12




 4.

      (a)



                       4(b)        15


                                                2023              2022
                                               6   30             6    30




                                               976,681            755,335
                                                31,332                19,839




                                                   4,064               1,707


                                              1,012,077           776,881


                                        10%


            2023   6   30                      3,870       2022       12    31
                   4,400




57
4.

     (b)




           

                                              (i)
                 (ii)         (iii)


           

                        (i)           (ii)          (iii)



           




           (i)




                                             2023           58
 4.

      (b)

            (i)


                             2023   6    30




                  976,681     21,740           4,064     1,002,485
                        –     9,592                –      9,592


                  976,681     31,332           4,064     1,012,077
                    1,091           –        81,273       82,364


                  977,772     31,332          85,337     1,094,441


                  432,375     10,021           2,922      445,318


                             2022 6 30




                  614,851      9,821            1,707      626,379
                  140,484     10,018                –     150,502


                  755,335     19,839            1,707      776,881
                      789           –        165,600      166,389


                  756,124     19,839          167,307      943,270


                  358,054      8,514            5,141      371,709




59
4.

     (b)

           (ii)


                     2023                2022
                    6   30              6   30




                    445,318             371,709
                        2,481               6,233


                    447,799             377,942


           (iii)




                     2023                2022
                    6   30              6   30




                    722,607             605,540
                    289,470             171,341


                   1,012,077            776,881




                     2023                2022
                    6   30             12   31




                   1,792,236           1,880,102
                    358,973             348,787


                   2,151,209           2,228,889


                                2023                60
 5.

            2023          2022
            6   30        6    30




            15,108             9,710
            60,861            68,683
            15,081            18,775
                (100)           (142)
                7,523          5,024
                1,099          3,792
                     –       14,366
                 197            204


            99,769        120,412


 6.




      (a)

            2023          2022
            6   30        6    30




                  85            156
                1,596          1,571


                1,681          1,727




61
6.

     (b)

                                    2023               2022
                                    6    30            6    30




                                264,758                220,318
                                    23,422                 15,270
                                        3,156               6,284


                                291,336                241,872




                            7.65%       2023
           160,200                             5%
                     100%




                                                2023                62
 6.

      (c)

            2023        2022
            6   30      6    30




                3,754        8,920




            37,373          28,789
            16,088          12,851


                4,084        1,406


 7.

            2023        2022
            6   30      6    30




            53,350          55,774


            53,350          55,774




            (25,922)         8,990


            27,428          64,764




63
8.

     (a)

                                                               90,627,000    2022   6    30
           371,120,000


                                                                                2023                       2022
                                                                                6   30                    6    30




            1 1                                                             535,678,676          381,246,492
                  2022                                                                   –      152,424,744
                                                                               (453,487)                  (189,532)
                                                                                         –                    4,900


            6 30                                                            535,225,189          533,486,604




     (b)

                                                               90,627,000    2022   6    30
           371,120,000


                                                                                2023                       2022
                                                                                6   30                    6    30




            6 30                                                            535,225,189          533,486,604
                                                                               414,507                1,696,145
                                                (i)                             68,500                              –
                                                                              1,230,998               2,793,039


            6 30                                                            536,939,194          537,975,788


            (i)   2022   11   17   2022     A                  2022                           2023    1    6
                                   68,500             2022 A                                  39.87




                                                                                              2023                       64
 9.

       95,048,000   2022   6   30             169,338,000



 10.




                                      2023              2022
                                     6   30           12 31




                                     671,743           787,405
                                              –            14


                                     671,743           787,419




                                     931,112         1,071,026
                                              –            150


                                     931,112         1,071,176


                                    1,602,855        1,858,595




65
10.

      (a)




                2022   1 1          74,102      160,208             234,310
                                   674,185    1,018,865           1,693,050
                       *                 –      15,321              15,321
                                         –    (415,573)           (415,573)
                                      (515)      (1,235)             (1,750)
                                    13,969      319,104             333,073
                                    25,664      (25,664)                  –


                2022   12    31   787,405     1,071,026           1,858,431
                                         –     17,420              17,420
                       *                 –     10,526              10,526
                                         –     (82,255)            (82,255)
                                      (421)      (2,076)             (2,497)
                                  (139,544)     (59,226)          (198,770)
                                   24,303       (24,303)                  –


                2023   6 30       671,743      931,112            1,602,855




            *




                                                           2023                66
 10.

       (b)




                                          2023   6   30




             2023   6    30       3   5                    130,000          5


                              5


                                                                     2023   6   30
                                                     10%             160,286,000
             2022   12   31               185,860,000




67
11.

                                                                                         2023                   2022
                                                                                        6     30               12    31




                                                                                       317,749                  317,749
                                  (i)                                                  193,483                  168,174


                                                                                       511,232                  485,923




                           (ii)                                                        214,442                  381,326
                                        (iii)                                                      –               27,145


                                                                                       214,442                  408,471


                                                                                       725,674                  894,394




      (i)       2022   3    30
                                                200,000,000        2022 4            130,000,000


                2022   3    30
                                                     50,000,000       2022   4              25,000,000          2023      5
                           25,000,000


      (ii)


      (iii)     2021   6    21                                                   A
              43,620,000          1,200,000         2023 6    30




                                                                                                        2023                  68
 12.

                                      2023                   2022
                                      6    30              12 31




                                       17,794                17,794
                                       46,749                28,240
                                          3,652               4,857


                                       68,195                50,891


 13.




                                      2023                   2022
                                      6    30              12 31




                                      307,292               350,182
                                                –                  –


                                      307,292               350,182


        2023   6   30                                339,397,000
       2022 6 30        221,146,000


 14.

                                      2023                   2022
                                      6    30              12 31




                                      898,506               782,179
                                          (9,169)             (8,931)


                                      889,337               773,248




69
15.

      (a)

              2023                2022
             6   30             12   31




             105,404             129,123


                 (527)               (646)


             104,877             128,477




      (b)

              2023                2022
             6   30             12   31




            1,394,820           1,294,707


              2023                2022
             6   30              6   30




             544,789             368,338




                         2023                70
 16.

                 2023         2022
                 6   30      12 31




                 175,157     207,998
                 (12,589)      (8,561)


                 162,568     199,437


                     7,267    12,186


                 169,835     211,623


       21   45




                 2023         2022
                 6   30      12 31




                 144,216     173,842
                  15,110      20,756
                     2,543     1,995
                      699      2,844


                 162,568     199,437




71
17.

        2023                  2022
       6   30               12    31




        69,795                   37,166
        10,569                   10,785
           7,682                  9,515
           8,148                  6,974
           6,353                  3,324
           1,190                  1,168


       103,737                   68,932


           (881)                   (551)


       102,856                   68,381




18.

        2023                  2022
       6   30               12    31




                –                     1
      3,040,541             2,916,847


      3,040,541             2,916,848


        (12,992)              (17,379)


      3,027,549             2,899,469




                     2023                  72
 19.

                     2023         2022
                     6   30      12 31




                     49,150      127,309


       2023 6   30


                     2023         2022
                     6   30      12 31




                     47,320      126,749
                         1,830      560


                     49,150      127,309


       2023 6   30




73
20.

                                                                                                           2023                         2022
                                                                                                           6    30                 12     31




                                                                                                           85,503                   125,638
                                                                                                           75,969                       70,903
                           23                                                                             214,258                              –
                                                                                                                6,432                   10,334
                                                                                                           17,548                       29,441
                                                                                                                       –               90,209
                                                                                                                4,661                    8,979


                                                                                                          404,371                   335,504




21.

       2019      8    15                 2019                                                                                      2019
           2019                                      2019    9     9                   2019               2019
                 1,124,000                 405,000                                                               2019       10     14
                                                                              48.11              1
            24.06


        2020      6   24                        2019                   2019                                            175,000
      63,000                                                              2020    8    11
                                    94.77                    1                                                 47.39



       2020      7    15                 2020                                                            2020                             2020
       7    17                      2020                         2,089,000                                                              2020        8
       31                                                                      94.77                 1


       2022      1    19                 2022                                                                        2021
                      2022      1   28                      2021                              366,300
                                    2022        3   29                                                           83.97




                                                                                                                            2023                    74
 21.

        2022 6          24         2022                   H                   2022 H               2022
        H                                                H              H                          2023
        6     30


        2022       11    17            2022                     2022     A             2023    1   6
                                 68,500       2022 A                                          39.87


       2022                     2022     H




       (a)




                    2020 6 24          2019         108,000
                                                                       (ii)
                    2020 7 17          2020         186,000
                                                                       (i)




                    2019 9 9       2019           1,124,000
                                                                       (i)
                    2020 6 24          2019            67,000
                                                                       (ii)
                    2020 7 17          2020       1,904,000
                                                                       (i)


                                                  3,389,000




75
21.

      (a)



            (i)
                                               50%   30%   20%


            (ii)
                                    50%        50%




                   2023 6 30                          2022 6 30




                   47.90        1,238,675             42.14           2,164,253
                           –             –          67.44             (29,400)
                           –             –          55.53            (139,825)


                   47.90        1,238,675             59.49           1,995,028


                           –    530,494                      –              –




                                                               2023                76
 21.

       (b)




                        2019 9 9    2019   120,000
                                                     (i)




                        2019 9 9    2019   285,000
                                                     (i)
                        2020 6 24   2019    63,000
                                                     (ii)
                        2022 1 28   2021   366,300
                                                     (iii)


                                           834,300




             (i)
                                                                         50%   30% 20%


             (ii)
                                                             50%   50%


             (      )
                                                                         40%   30% 30%




77
21.

      (b)




                                                                                        2023                   2022
                                                                                       6   30                 6     30




                                                                                       516,113                266,417
                                                                                                –            366,300
                                                                                      (187,880)                          –


                                                                                       328,233                632,717


                  2019   9   9   2020     6   24    2022   1   28
                                                                        38.44         47.22                 12.91


      (c)




                    2022 11 17     2022                        68,500
                   A                                                            (i)


                                                               68,500




            (i)


                                 50%    30%   20%




                                                                                                     2023                     78
 21.

       (c)




                                                   2023        2022
                                                   6   30      6   30




                                                   68,500               –


                                                   68,500               –


             2022    11   17               38.76



       (d)

              2023    6   30                       3,156,000   2022          6
             30                6,284,000




79
22.

      (a)

                         2023                   2022
                         6    30                6    30




            1 1          55,879                     21,587
                                   –                 (166)
                         53,350                     55,774
                                   –                 (135)
                         (90,527)               (44,255)


            6 30         18,702                     32,805




                   17        (6,353)                (3,442)
                         25,055                     36,247


                         18,702                     32,805


      (b)




                          2023                   2022
                         6 30                  12 31




                         33,179                     32,613
                        (163,246)              (188,243)


                        (130,067)              (155,630)




                                        2023                  80
 23.

       (a)

                                           2023   6     30                  2022 6      30



       (b)

                    2023   6    9         2022                   2022

                                        2022                                                      0.4



                                                 2022                                        10
                                    4

                           2022                         2023 7

 24.




             2022    1 1                                                 381,246,492          381,246
                                                                            366,300                 366
                                                                           1,516,647              1,517
                                                                         152,626,122          152,626
                                                                             (76,885)               (76)


             2022    12    31                                            535,678,676          535,679


             2023    6 30                                               535,678,676           535,679




81
25.

      (a)

                            13




      (b)




                                 2023           2022
                                 6   30        12    31




                                          –        27,145


                                 158,720        158,720
                                 317,749        317,749
                                 193,483        168,174
                                 214,442        381,326


            2023   6   30




                                                             2023   82
 25.

       (b)

             (i)

                                                                   2023   6   30



             (ii)



                                                                                   2023   6
                     30
                              2,027,000




                                                 2023     6   30
                                                 311,000




                                          2023   6   30


                    681,000




83
25.

      (b)

            (ii)




                   2022 1 1     105,661          –          605,534                  –
                                      –   317,425           596,500            155,000
                                      –         –           19,685                  –


                                      –       324              9,321            13,174
                                 53,059          –                 –                –
                                      –         –          (849,714)                –


                   2022 12 31   158,720    317,749           381,326            168,174


                                      –         –          120,000             25,000


                                      –         –            6,641               309
                                      –         –                 –                –
                                      –         –      (293,525)                    –


                   2023 6 30    158,720    317,749           214,442            193,483


      (c)

                                                  2023   6    30




                                                                         2023              84
 26.

        2023 6   30


                                     2023       2022
                                    6 30      12 31




                                    193,048    158,578


 27.

       (a)




             Biorichland LLC




             JOINN Biologics Inc.




85
27.

      (b)

                               2023                 2022
                               6   30               6   30




                                        –               415


                               31,665                   9,828


                                   249                       –


                                    93                       –


                                    81                       –


            2023


            5


                   2,339,000       50%




                                             2023                 86
 27.

       (c)




              2023      2022
             6 30     12 31




             15,098     12,259


              9,608      9,461




              1,115            –
                728       702




             17,679     30,975
                759       796
                573       686




87
27.

      (d)

               2023   6   30                                  6,527,000       2022    6    30
                            6,377,000


      (e)

                  2021




                                                       6,025,000                    41,858,000
                           2023   6     30                         652,000
                4,545,000


                  2023


                                                           7,723,000         2023   6 30
                                             696,000




                                                                             2023                88